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Clinical Pharmacokinetics
Volumn 40, Issue 3, 2001, Pages 159-168
The gut as a barrier to drug absorption: Combined role of cytochrome P450 3A and P-glycoprotein
Author keywords

[No Author keywords available]
Indexed keywords

AMIODARONE; ANTIARRHYTHMIC AGENT; ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; ATORVASTATIN; CALCIUM CHANNEL BLOCKING AGENT; CYCLOSPORIN; CYTOCHROME P450 3A; DIGOXIN; ETOPOSIDE; GLYCOPROTEIN P; IMMUNOSUPPRESSIVE AGENT; INDINAVIR; ITRACONAZOLE; KETOCONAZOLE; LIDOCAINE; MIDAZOLAM; NELFINAVIR; PACLITAXEL; QUINIDINE; RAPAMYCIN; RIFAMPICIN; RITONAVIR; SAQUINAVIR; TACROLIMUS; TALINOLOL; UNINDEXED DRUG; VINBLASTINE; VINCRISTINE;
EID: 0035054725     PISSN: 03125963     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003088-200140030-00002     Document Type: Review
Times cited : (512)
References (5)
  • 1
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    • Benet LZ, Wu CY, Hebert MF, et al. Intestinal drug metabolism and antitransport processes: a potential paradigm shift in oral drug delivery. J Controlled Release 1996; 39: 139-43
    • (1996) J Controlled Release , vol.39 , pp. 139-143
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  • 2
    • 0029028792 scopus 로고
    • Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
    • Wacher VJ, Wu CY, Benet LZ. Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol Carcinog 1995; 13: 129-34
    • (1995) Mol Carcinog , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.Y.2    Benet, L.Z.3
  • 3
    • 0030059953 scopus 로고    scopus 로고
    • Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells
    • Schuetz EG, Beck WT, Schuetz JD. Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol Pharmacol 1996; 49: 311-8
    • (1996) Mol Pharmacol , vol.49 , pp. 311-318
    • Schuetz, E.G.1    Beck, W.T.2    Schuetz, J.D.3
  • 4
    • 0025719746 scopus 로고
    • First-pass metabolism of cyclosporine by the gut
    • Kolars JC, Awni WM, Merion RM, et al. First-pass metabolism of cyclosporine by the gut. Lancet 1991; 338: 1488-90
    • (1991) Lancet , vol.338 , pp. 1488-1490
    • Kolars, J.C.1    Awni, W.M.2    Merion, R.M.3
  • 5
    • 0029738490 scopus 로고    scopus 로고
    • First-pass metabolism of midazolam by the human intestine
    • Paine MF, Shen DD, Kunze KL, et al. First-pass metabolism of midazolam by the human intestine. Clin Pharmacol Ther 1996; 60: 14-24
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 14-24
    • Paine, M.F.1    Shen, D.D.2    Kunze, K.L.3

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.