Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes

Biochemical Pharmacology

Volumn 70, Issue 4, 2005, Pages 500-510

  Wu, Chung Pu ^a,b   Klokouzas, Antonios ^a,b   Hladky, Stephen B ^a   Ambudkar, Suresh V ^b   Barrand, Margery A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

ATP hydrolysis; Erythrocyte membranes; Mefloquine; MK 571; Multidrug resistance associated proteins 1 and 4

Indexed keywords

2,4 DINITROPHENOL; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; AMODIAQUINE; ANTIMALARIAL AGENT; CALCEIN; CHLOROQUINE; CYCLIC GMP; GLUTATHIONE DERIVATIVE; GLUTATHIONE DISULFIDE; MEFLOQUINE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; PRIMAQUINE; PROSTAGLANDIN E1; QUERCETIN; QUINIDINE; QUININE; QUINOLINE DERIVATIVE; VERLUKAST;

ARTICLE; BINDING SITE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVITY; ERYTHROCYTE MEMBRANE; HUMAN; HUMAN CELL; IC 50; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; TRANSPORT KINETICS;

ANTIMALARIALS; CELL LINE, TUMOR; ERYTHROCYTE MEMBRANE; FLUOROMETRY; HUMANS; MEFLOQUINE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS;

EID: 22144455747     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.05.022     Document Type: Article

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