ATP-dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P

Molecular Pharmacology

Volumn 55, Issue 5, 1999, Pages 921-928

  Chen, Zhe Sheng ^a   Furukawa, Tatsuhiko ^a   Sumizawa, Tomoyuki ^a   Ono, Kenji ^b   Ueda, Kazumitsu ^c   Seto, Kiyotomo ^d   Akiyama, Shin Ichi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ADENOSINE TRIPHOSPHATE; DNA TOPOISOMERASE; IRINOTECAN; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; CANCER CELL; CYTOTOXICITY; EFFUSION; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ADENOSINE TRIPHOSPHATE; ANION TRANSPORT PROTEINS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; BUTHIONINE SULFOXIMINE; CAMPTOTHECIN; CARRIER PROTEINS; CELL LINE; CELL SURVIVAL; CULTURE MEDIA; CYCLIC P-OXIDES; DNA TOPOISOMERASES, TYPE I; DRUG RESISTANCE, MULTIPLE; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; KB CELLS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NICOTINIC ACIDS; PROPIONATES; QUINOLINES;

EID: 0032946239     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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