Multiple flavonoid-binding sites within multidrug resistance protein MRP1

Cellular and Molecular Life Sciences

Volumn 60, Issue 10, 2003, Pages 2164-2177

  Trompier, D ^a   Baubichon Cortay, H ^a   Chang, X B ^b   Maitrejean, M ^a   Barron, D ^a   Riordan, J R ^b   Di Pietro, A ^a  

^a UNIVERSITÉ LYON 1   (France)

^b MAYO CLINIC   (United States)

Author keywords

ABC transporter; Chemosensitization; Drug binding site; Flavonoid; Multidrug resistance (MDR); Multidrug resistance protein 1 (MRP1); Nucleotide binding domain (NBD)

Indexed keywords

ABC TRANSPORTER; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; DEHYDROSILYBIN; FLAVONOID; GLUTATHIONE; LEUKOTRIENE C4; MULTIDRUG RESISTANCE PROTEIN 1; NUCLEOTIDE BINDING PROTEIN; SILIBININ; UNCLASSIFIED DRUG; VANADIC ACID; VINCRISTINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL GROWTH; CHEMOSENSITIVITY; CONTROLLED STUDY; CROSS RESISTANCE; CYTOSOL; ENZYME ACTIVITY; ISOPRENYLATION; MEMBRANE VESICLE; NONHUMAN; PROTEIN EXPRESSION;

ADENOSINE DIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BINDING SITES; CLONING, MOLECULAR; CRICETINAE; FLAVONOIDS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PROTEIN STRUCTURE, TERTIARY; VINCRISTINE;

ANIMALIA;

EID: 0242383477     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3177-6     Document Type: Article

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