-
1
-
-
0030004763
-
Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein
-
Ayesh, S., Shao, Y.-M. & Stein, W. D. (1996) Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein, Biochim. Biophys, Acta 1316, 8 - 18.
-
(1996)
Biochim. Biophys, Acta
, vol.1316
, pp. 8-18
-
-
Ayesh, S.1
Shao, Y.-M.2
Stein, W.D.3
-
2
-
-
0026669363
-
Characterization of the azidopine and vinblastine binding site of P-glycoprotein
-
Bruggemann, E. P., Currier, S. J., Gottesman, M, M. & Pastan, I. (1992) Characterization of the azidopine and vinblastine binding site of P-glycoprotein, J. Biol. Chem. 267, 21 020 - 21 026.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 21020-21026
-
-
Bruggemann, E.P.1
Currier, S.J.2
Gottesman, M.M.3
Pastan, I.4
-
3
-
-
0027411980
-
A new mammalian DNA topoisomerase I poison Hoechst 33342: Cytotoxicity and drug resistance in human cell cultures
-
Chen, A. Y., Yu. C., Bodley, A., Peng, L. F. & Liu, L. F. (1993) A new mammalian DNA topoisomerase I poison Hoechst 33342: cytotoxicity and drug resistance in human cell cultures, Cancer Res. 53, 1332 - 1337.
-
(1993)
Cancer Res.
, vol.53
, pp. 1332-1337
-
-
Chen, A.Y.1
Yu, C.2
Bodley, A.3
Peng, L.F.4
Liu, L.F.5
-
4
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Cole, S. P. C., Bhardwaj, G., Gerlach, J. H., Mackie, J. E., Grant, C. E., Almquist, K. C., Stewart, A. J., Kurz, E. U., Dunean, A. M. V. & Deeley, R. G. (1992) Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line, Science 258, 1650 - 1654.
-
(1992)
Science
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.C.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Dunean, A.M.V.9
Deeley, R.G.10
-
5
-
-
0028172728
-
Modulation of Adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells; activation of P-glycoprotein as a possible mechanism
-
Critchfield, J. W., Welsh, C. J., Phang, J. M. & Yeh, G. C. (1994) Modulation of Adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells; activation of P-glycoprotein as a possible mechanism, Biochem. Pharmacol. 48, 1437 - 1445.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1437-1445
-
-
Critchfield, J.W.1
Welsh, C.J.2
Phang, J.M.3
Yeh, G.C.4
-
6
-
-
0030597326
-
Competitive inhibition of photoaffinity labeling of P-glycoprotein by anticancer drugs and modulators including S9788
-
Demmer, A., Dunn, T., Hoof, T., Kubesch, P. & Tümmler, B. (1996) Competitive inhibition of photoaffinity labeling of P-glycoprotein by anticancer drugs and modulators including S9788, Eur. J. Pharmacol. 315, 338 - 343.
-
(1996)
Eur. J. Pharmacol.
, vol.315
, pp. 338-343
-
-
Demmer, A.1
Dunn, T.2
Hoof, T.3
Kubesch, P.4
Tümmler, B.5
-
8
-
-
0031039693
-
Competitive and non-competitive inhibition of the multidrug-resistance-associated P-glycoprotein ATPase: Further experimental evidence for a multisite model
-
Garrigos, M., Mir, L. M. & Orlowski, S. (1997) Competitive and non-competitive inhibition of the multidrug-resistance-associated P-glycoprotein ATPase: further experimental evidence for a multisite model, Eur. J. Biochem. 244, 664 - 673.
-
(1997)
Eur. J. Biochem.
, vol.244
, pp. 664-673
-
-
Garrigos, M.1
Mir, L.M.2
Orlowski, S.3
-
9
-
-
0029954843
-
P-glycoprotein - A mediator of multidrug resistance in tumour cells
-
Germann, U. A. (1996) P-glycoprotein - a mediator of multidrug resistance in tumour cells, Eur. J. Cancer 32A, 927 - 944.
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 927-944
-
-
Germann, U.A.1
-
10
-
-
0029944634
-
Reversal of multidrug resistance by valinomycin is overcome by CCCP
-
Goda, K., Krasznai, Z., Gáspár, R., Lankelma, J., Westerhoff, H. V., Damjanovich, S. & Szabó, G. Jr (1996) Reversal of multidrug resistance by valinomycin is overcome by CCCP, Biochem. Biophys. Res. Commun. 219, 306 - 310.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.219
, pp. 306-310
-
-
Goda, K.1
Krasznai, Z.2
Gáspár, R.3
Lankelma, J.4
Westerhoff, H.V.5
Damjanovich, S.6
Szabó Jr., G.7
-
11
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman, M. M. & Pastan, I. (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter, Annu. Rev. Biochem. 62, 385 - 427.
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
12
-
-
0025872032
-
Domain mapping of the photoaffinity drug-binding sites in P-glycoprotein encoded by mouse mdr 1b
-
Greenberger, L. M., Lisanti, C. J., Silva, J. T. & Horwitz, S. B. (1991) Domain mapping of the photoaffinity drug-binding sites in P-glycoprotein encoded by mouse mdr 1b, J. Biol. Chem. 266, 20 744 - 20 751.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 20744-20751
-
-
Greenberger, L.M.1
Lisanti, C.J.2
Silva, J.T.3
Horwitz, S.B.4
-
13
-
-
0027216104
-
Major photoaffinity drug labeling sites for iodoarylazidoprazosin in P-glycoprotein are within, or immediately C-termmat to, transmembrane domains 6 and 12
-
Greenberger, L. M. (1993) Major photoaffinity drug labeling sites for iodoarylazidoprazosin in P-glycoprotein are within, or immediately C-termmat to, transmembrane domains 6 and 12, J. Biol. Chem. 268, 11 417 - 11 425.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11417-11425
-
-
Greenberger, L.M.1
-
14
-
-
0028178689
-
Cooperative P-glycoprotein-mediated daunorubicin transport into DNA-loaded plasma membrane vesicles
-
Guiral, M., Viratelle, O., Westerhoff, H. V. & Lankelma, J. (1994) Cooperative P-glycoprotein-mediated daunorubicin transport into DNA-loaded plasma membrane vesicles, FEBS Lett. 346, 141 - 145.
-
(1994)
FEBS Lett.
, vol.346
, pp. 141-145
-
-
Guiral, M.1
Viratelle, O.2
Westerhoff, H.V.3
Lankelma, J.4
-
15
-
-
0027181852
-
Functional expression of P-glycoprotein in apical membranes of human Caco-2 cells: Kinetics of vinblastine secretion and interaction with modulators
-
Hunter, J., Jepson, M. A., Tsuruo, T., Simmons, N. L. & Hirst, B. H. (1993) Functional expression of P-glycoprotein in apical membranes of human Caco-2 cells: kinetics of vinblastine secretion and interaction with modulators, J. Biol. Chem. 268, 14 991 - 14 997.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14991-14997
-
-
Hunter, J.1
Jepson, M.A.2
Tsuruo, T.3
Simmons, N.L.4
Hirst, B.H.5
-
16
-
-
0029905732
-
Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p
-
Kolaczkowski, M., van der Rest, M., Cybularz-Kolaczkowska, A., Soumillion, J.-P., Konings, W. N. & Goffeau, A. (1996) Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p, J. Biol. Chen. 271, 31 543 - 31 548.
-
(1996)
J. Biol. Chen.
, vol.271
, pp. 31543-31548
-
-
Kolaczkowski, M.1
Van Der Rest, M.2
Cybularz-Kolaczkowska, A.3
Soumillion, J.-P.4
Konings, W.N.5
Goffeau, A.6
-
18
-
-
0028589070
-
3H]vinblastine binding to P-glycoprotein of CCRF ADR5000 cells
-
3H]vinblastine binding to P-glycoprotein of CCRF ADR5000 cells, Eur. J. Pharmacol. 288, 105 - 114.
-
(1994)
Eur. J. Pharmacol.
, vol.288
, pp. 105-114
-
-
Malkhandi, J.1
Ferry, D.R.2
Boer, R.3
Gekeler, V.4
Ise, W.5
Kerr, D.J.6
-
19
-
-
0028128286
-
Localization of the forskolin labeling sites to both halves of P-glycoprotein: Similarity of the sites labeled by forskolin and prazosin
-
Morris, D. I., Greenberger, L. M., Bruggemann, E. P., Cardarelli, C., Gottesman, M. M., Pastan, I. & Seamon, K. B. (1994) Localization of the forskolin labeling sites to both halves of P-glycoprotein: similarity of the sites labeled by forskolin and prazosin, Mol. Pharmacol. 46, 329 - 337.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 329-337
-
-
Morris, D.I.1
Greenberger, L.M.2
Bruggemann, E.P.3
Cardarelli, C.4
Gottesman, M.M.5
Pastan, I.6
Seamon, K.B.7
-
20
-
-
0030035535
-
Effects of steroids and verapamil on P-glycoprotein ATPase activity: Progesterone, desoxycorticosterone, and verapamil are mutually non-exclusive modulators
-
Orlowski, S., Mir, L. M., Belehradek, J. Jr & Garrigos, M. (1996) Effects of steroids and verapamil on P-glycoprotein ATPase activity: progesterone, desoxycorticosterone, and verapamil are mutually non-exclusive modulators, Biochem. J. 317, 515 - 522.
-
(1996)
Biochem. J.
, vol.317
, pp. 515-522
-
-
Orlowski, S.1
Mir, L.M.2
Belehradek Jr., J.3
Garrigos, M.4
-
21
-
-
0028097634
-
Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity
-
Pawagi, A. B., Wang, J., Silverman, M., Reithmeier, R. A. F. & Deber, C. M. (1994) Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity, J. Mol. Biol. 235, 554 - 564.
-
(1994)
J. Mol. Biol.
, vol.235
, pp. 554-564
-
-
Pawagi, A.B.1
Wang, J.2
Silverman, M.3
Reithmeier, R.A.F.4
Deber, C.M.5
-
22
-
-
0027952904
-
Non-competitive inhibition of P-glycoprotein-associated efflux of THP-adriamycin by verapamil in living K562 leukemia cells
-
Pereira, E., Borrel, M. N., Fiallo, M. & Garnier-Suillerot, A. (1994) Non-competitive inhibition of P-glycoprotein-associated efflux of THP-adriamycin by verapamil in living K562 leukemia cells, Biochim. Biophys. Acta 1225, 209 - 216.
-
(1994)
Biochim. Biophys. Acta
, vol.1225
, pp. 209-216
-
-
Pereira, E.1
Borrel, M.N.2
Fiallo, M.3
Garnier-Suillerot, A.4
-
23
-
-
0027132062
-
Flavonol-stimulated efflux of 7,12 dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells
-
Phang, J. M., Poore, C. M., Lopaczynska, J. & Yeh, G. C. (1993) Flavonol-stimulated efflux of 7,12 dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells, Cancer Res. 53, 5977 - 5981.
-
(1993)
Cancer Res.
, vol.53
, pp. 5977-5981
-
-
Phang, J.M.1
Poore, C.M.2
Lopaczynska, J.3
Yeh, G.C.4
-
24
-
-
0028307550
-
Phosphatidylcholine translocase: A physiological role for the mdr2 gene
-
Ruetz, S. & Gros, P. (1994) Phosphatidylcholine translocase: a physiological role for the mdr2 gene, Cell 77, 1071 - 1081.
-
(1994)
Cell
, vol.77
, pp. 1071-1081
-
-
Ruetz, S.1
Gros, P.2
-
25
-
-
0023226943
-
Identification of the multidrug resistance-related membrane glycoprotein as an acceptor of calcium channel blockers
-
Safa, A. R., Glover, C. J., Sewell, J. L., Meyers, M. B., Biedler, J. L. & Felsted, R. L. (1987) Identification of the multidrug resistance-related membrane glycoprotein as an acceptor of calcium channel blockers, J. Biol. Chem. 262, 7884 - 7888.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 7884-7888
-
-
Safa, A.R.1
Glover, C.J.2
Sewell, J.L.3
Meyers, M.B.4
Biedler, J.L.5
Felsted, R.L.6
-
26
-
-
0028177317
-
125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein. spiperophilin, in human neuroblastoma cells
-
125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein. spiperophilin, in human neuroblastoma cells, Biochemistry 33, 256 - 265.
-
(1994)
Biochemistry
, vol.33
, pp. 256-265
-
-
Safa, A.R.1
Agresti, M.2
Bryk, D.3
Tamai, I.4
-
27
-
-
0030566751
-
The multidrug transporters - Proteins of an ancient immune system
-
Sarkadi, B., Müller, M. & Holló. Z. (1996) The multidrug transporters - proteins of an ancient immune system, Immunol. Lett. 54, 215 - 219.
-
(1996)
Immunol. Lett.
, vol.54
, pp. 215-219
-
-
Sarkadi, B.1
Müller, M.2
Holló, Z.3
-
28
-
-
0027981909
-
Quercetin potentiates the effect of Adriamycin in a multidrug-resistant MCF-7 human breast cancer cell line: P-glycoprotein as a possible target
-
Scambia, G., Ranelletti, F. O., Panici, P. B., DeVincenzo, R., Bonanno, G., Ferrandina, G., Piantelli, M., Bussa, S., Rumi, C., Cianfriglia, M. & Mancuso, S. (1994) Quercetin potentiates the effect of Adriamycin in a multidrug-resistant MCF-7 human breast cancer cell line: P-glycoprotein as a possible target, Cancer Chemother. Pharmacol. 34, 459 - 464.
-
(1994)
Cancer Chemother. Pharmacol.
, vol.34
, pp. 459-464
-
-
Scambia, G.1
Ranelletti, F.O.2
Panici, P.B.3
DeVincenzo, R.4
Bonanno, G.5
Ferrandina, G.6
Piantelli, M.7
Bussa, S.8
Rumi, C.9
Cianfriglia, M.10
Mancuso, S.11
-
29
-
-
0031049609
-
Mutually co-operative interactions between modulators of P-glycoprotein
-
Shao, Y., Ayesh, S. & Stein, W. D. (1997) Mutually co-operative interactions between modulators of P-glycoprotein, Biochim. Biophys. Acta 1360, 30 - 38.
-
(1997)
Biochim. Biophys. Acta
, vol.1360
, pp. 30-38
-
-
Shao, Y.1
Ayesh, S.2
Stein, W.D.3
-
30
-
-
0027937143
-
ATPase activity of purified and reconstituted P-glycoprotein from Chinese hamster ovary cells
-
Shapiro, A. B. & Ling, V. (1994) ATPase activity of purified and reconstituted P-glycoprotein from Chinese hamster ovary cells, J. Biol. Chem. 269, 3745 - 3754.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 3745-3754
-
-
Shapiro, A.B.1
Ling, V.2
-
31
-
-
0029061103
-
Reconstitution of drug transport by purified P-glycoprotein
-
Shapiro, A. B. & Ling, V. (1995) Reconstitution of drug transport by purified P-glycoprotein, J. Biol. Chem. 270, 16 167 - 16 175.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16167-16175
-
-
Shapiro, A.B.1
Ling, V.2
-
32
-
-
0031581819
-
Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein
-
Shapiro, A. B. & Ling, V. (1997) Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein, Biochem. Pharmacol. 53, 587 - 596.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 587-596
-
-
Shapiro, A.B.1
Ling, V.2
-
33
-
-
0030822996
-
P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer
-
Shapiro, A. B., Corder, A. B. & Ling, V. (1997) P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer, Eur. J. Biochem. 250, 115 - 121.
-
(1997)
Eur. J. Biochem.
, vol.250
, pp. 115-121
-
-
Shapiro, A.B.1
Corder, A.B.2
Ling, V.3
-
34
-
-
0027482461
-
Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein
-
Sharom, F. J., Yu, X. & Doige, C. A. (1993) Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein, J. Biol. Chem. 268, 24 197 - 24 202.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24197-24202
-
-
Sharom, F.J.1
Yu, X.2
Doige, C.A.3
-
35
-
-
0029987548
-
Synthetic hydrophobic peptides are substrates for P-glycoprotein and stimulate drug transport
-
Sharom, F. J., Yu, X., DiDiodato,. G. & Chu, J. W. K. (1996) Synthetic hydrophobic peptides are substrates for P-glycoprotein and stimulate drug transport, Biochem. J. 320, 421 - 428.
-
(1996)
Biochem. J.
, vol.320
, pp. 421-428
-
-
Sharom, F.J.1
Yu, X.2
DiDiodato, G.3
Chu, J.W.K.4
-
36
-
-
0027363563
-
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from the bile and to liver disease
-
Smit, J. J. M., Schinkel, A. H., Oude Elferink, R. P. J., Groen, A. K., Wagenaar, E., van Deemter, L., Moi, C. A. A. M., Ottenhofer, R., van der Lugt, N. M. T., van Roon, M. A., Offerhaus, G. J. A., Berns, A. J. M. & Borst, P. (1993) Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from the bile and to liver disease, Cell 75, 451 - 462.
-
(1993)
Cell
, vol.75
, pp. 451-462
-
-
Smit, J.J.M.1
Schinkel, A.H.2
Oude Elferink, R.P.J.3
Groen, A.K.4
Wagenaar, E.5
Van Deemter, L.6
Moi, C.A.A.M.7
Ottenhofer, R.8
Van Der Lugt, N.M.T.9
Van Roon, M.A.10
Offerhaus, G.J.A.11
Berns, A.J.M.12
Borst, P.13
-
37
-
-
0028264893
-
The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate
-
Spoelstra, E. C., Westerhoff, H. V., Pinedo, H. M., Dekker, H. & Lankelma, J. (1994) The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate, Eur. J. Biochem. 221, 363 - 373.
-
(1994)
Eur. J. Biochem.
, vol.221
, pp. 363-373
-
-
Spoelstra, E.C.1
Westerhoff, H.V.2
Pinedo, H.M.3
Dekker, H.4
Lankelma, J.5
-
38
-
-
0025991731
-
Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug-resistant cells
-
Tamai, I. & Safa, A. R. (1991) Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug-resistant cells, J. Biol. Chem. 266, 16 796 - 16 800.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 16796-16800
-
-
Tamai, I.1
Safa, A.R.2
-
39
-
-
0028362501
-
Characterization of the ATPase activity of purified Chinese hamster P-glycoprotein
-
Urbatsch, I. L., Al-Shawi, M. K. & Senior, A. E. (1994) Characterization of the ATPase activity of purified Chinese hamster P-glycoprotein, Biochemistry 33, 7069 - 7076.
-
(1994)
Biochemistry
, vol.33
, pp. 7069-7076
-
-
Urbatsch, I.L.1
Al-Shawi, M.K.2
Senior, A.E.3
-
40
-
-
0029744881
-
Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1
-
van Veen, H. W., Venema, K., Bolhuis, H., Oussenko, I., Kok, J., Poolman, B., Driessen, A. J. M. & Konings, W. (1996) Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1, Proc. Natl Acad. Sci. USA 93, 10668 - 10672.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 10668-10672
-
-
Van Veen, H.W.1
Venema, K.2
Bolhuis, H.3
Oussenko, I.4
Kok, J.5
Poolman, B.6
Driessen, A.J.M.7
Konings, W.8
|