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Volumn 68, Issue 3, 2006, Pages 213-228

Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis

Author keywords

Blood brain barrier; Drug resistance; Epilepsy; Hippocampal sclerosis; Multidrug resistance associated proteins; P glycoprotein

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; ETIRACETAM; GABAPENTIN; GLYCOPROTEIN P; LAMOTRIGINE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; MULTIDRUG RESISTANCE PROTEIN 6; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; TOPIRAMATE; VALPROIC ACID;

EID: 33644503533     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2005.11.011     Document Type: Article
Times cited : (118)

References (51)
  • 3
    • 18244396084 scopus 로고    scopus 로고
    • Entorhinal cortex involvement in human mesial temporal lobe epilepsy: An electrophysiologic and volumetric study
    • F. Bartolomei, M. Khalil, F. Wendling, A. Sontheimer, J. Régis, J.P. Ranjeva, M. Guye, and P. Chauvel Entorhinal cortex involvement in human mesial temporal lobe epilepsy: an electrophysiologic and volumetric study Epilepsia 46 2005 677 687
    • (2005) Epilepsia , vol.46 , pp. 677-687
    • Bartolomei, F.1    Khalil, M.2    Wendling, F.3    Sontheimer, A.4    Régis, J.5    Ranjeva, J.P.6    Guye, M.7    Chauvel, P.8
  • 5
    • 3242682550 scopus 로고    scopus 로고
    • Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier
    • V. Berezowski, C. Landy, M.-P. Dehouck, R. Cecchelli, and L. Fenart Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier Brain Res. 1018 2004 1 9
    • (2004) Brain Res. , vol.1018 , pp. 1-9
    • Berezowski, V.1    Landy, C.2    Dehouck, M.-P.3    Cecchelli, R.4    Fenart, L.5
  • 6
    • 0037314761 scopus 로고    scopus 로고
    • Mesial temporal damage in temporal lobe epilepsy: A volumetric MRI study of hippocampus, amygdala and parahippocampal region
    • N. Bernasconi, A. Bernasconi, S.B. Caramanos, Antel, F. Andermann, and D.L. Arnold Mesial temporal damage in temporal lobe epilepsy: a volumetric MRI study of hippocampus, amygdala and parahippocampal region Brain 126 2003 462 469
    • (2003) Brain , vol.126 , pp. 462-469
    • Bernasconi, N.1    Bernasconi, A.2    Caramanos, S.B.3    Antel4    Andermann, F.5    Arnold, D.L.6
  • 7
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • P. Borst, R. Evers, M. Kool, and J. Wijnholds A family of drug transporters: the multidrug resistance-associated proteins J. Natl. Cancer Inst. 92 2000 1295 1302
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3    Wijnholds, J.4
  • 11
    • 0034214069 scopus 로고    scopus 로고
    • Functional expression of P-glycoprotein and multidrug resistance-associated protein (Mrp1) in primary cultures of rat astrocytes
    • X. Declèves, A. Regina, J.L. Laplanche, F. Roux, B. Boval, J.M. Launay, and J.M. Scherrmann Functional expression of P-glycoprotein and multidrug resistance-associated protein (Mrp1) in primary cultures of rat astrocytes J. Neurosci. Res. 60 2000 594 601
    • (2000) J. Neurosci. Res. , vol.60 , pp. 594-601
    • Declèves, X.1    Regina, A.2    Laplanche, J.L.3    Roux, F.4    Boval, B.5    Launay, J.M.6    Scherrmann, J.M.7
  • 15
    • 0036199457 scopus 로고    scopus 로고
    • Permeability of porcine blood brain barrier to somatostatin analogues
    • G. Fricker, S. Nobmann, and D.S. Miller Permeability of porcine blood brain barrier to somatostatin analogues Br. J. Pharmacol. 135 2002 1308 1314
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 1308-1314
    • Fricker, G.1    Nobmann, S.2    Miller, D.S.3
  • 16
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • M.M. Gottesman, T. Fojo, and S.E. Bates Multidrug resistance in cancer: role of ATP-dependent transporters Nat. Rev. Cancer 2 2002 48 58
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 17
    • 0027092617 scopus 로고
    • Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells
    • E.J. Hegmann, H.C. Bauer, and R.S. Kerbel Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells Cancer Res. 52 1992 6969 6975
    • (1992) Cancer Res. , vol.52 , pp. 6969-6975
    • Hegmann, E.J.1    Bauer, H.C.2    Kerbel, R.S.3
  • 18
    • 0036325998 scopus 로고    scopus 로고
    • Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurons
    • J. Hirrlinger, J. Koenig, and R. Dringen Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurons J. Neurochem. 82 2002 716 719
    • (2002) J. Neurochem. , vol.82 , pp. 716-719
    • Hirrlinger, J.1    Koenig, J.2    Dringen, R.3
  • 20
    • 0030841332 scopus 로고    scopus 로고
    • Analysis of expression of cMOAT (MRP2), MRP2, MRP3, MRP4 and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
    • M. Kool, M. De Hass, G.L. Scheffer, R.L. Scheper, van Eijk, J.T. Michel, J.A. Juijn, F. Baas, and P. Borst Analysis of expression of cMOAT (MRP2), MRP2, MRP3, MRP4 and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines Cancer Res. 57 1997 3537 3547
    • (1997) Cancer Res. , vol.57 , pp. 3537-3547
    • Kool, M.1    De Hass, M.2    Scheffer, G.L.3    Scheper, R.L.4    Eijk, V.5    Michel, J.T.6    Juijn, J.A.7    Baas, F.8    Borst, P.9
  • 21
    • 0035254189 scopus 로고    scopus 로고
    • Efflux transport systems for drugs at the blood-brain barrier and blood-cerebrospinal fluid barrier (Part 2)
    • H. Kusuhara, and Y. Sugiyama Efflux transport systems for drugs at the blood-brain barrier and blood-cerebrospinal fluid barrier (Part 2) Drug Discov. Today 6 2001 206 212
    • (2001) Drug Discov. Today , vol.6 , pp. 206-212
    • Kusuhara, H.1    Sugiyama, Y.2
  • 22
    • 13244298981 scopus 로고    scopus 로고
    • Potential role of drug transporters in the pathogenesis of medically intractable epilepsy
    • P. Kwan, and M.J. Brodie Potential role of drug transporters in the pathogenesis of medically intractable epilepsy Epilepsia 46 2005 224 235
    • (2005) Epilepsia , vol.46 , pp. 224-235
    • Kwan, P.1    Brodie, M.J.2
  • 23
    • 0037305372 scopus 로고    scopus 로고
    • Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues
    • T. Langmann, R. Mauerer, A. Zahn, C. Moehle, M. Probst, W. Stremmel, and G. Schmitz Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues Clin. Chem. 49 2003 230 238
    • (2003) Clin. Chem. , vol.49 , pp. 230-238
    • Langmann, T.1    Mauerer, R.2    Zahn, A.3    Moehle, C.4    Probst, M.5    Stremmel, W.6    Schmitz, G.7
  • 24
    • 0036128985 scopus 로고    scopus 로고
    • Role of multidrug transporters in pharmacoresistance to antiepileptic drugs
    • W. Loscher, and H. Potschka Role of multidrug transporters in pharmacoresistance to antiepileptic drugs J. Pharmacol. Exp. Ther. 301 2002 7 14
    • (2002) J. Pharmacol. Exp. Ther. , vol.301 , pp. 7-14
    • Loscher, W.1    Potschka, H.2
  • 25
    • 22744440362 scopus 로고    scopus 로고
    • Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases
    • W. Loscher, and H. Potschka Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases Prog. Neurobiol. 76 2005 22 76
    • (2005) Prog. Neurobiol. , vol.76 , pp. 22-76
    • Loscher, W.1    Potschka, H.2
  • 26
    • 0042468096 scopus 로고    scopus 로고
    • Impact of drug transporter studies on drug discovery and development
    • N. Mizuno, T. Niwa, Y. Yotsumoto, and Y. Sugiyama Impact of drug transporter studies on drug discovery and development Pharmacol. Rev. 55 2003 425 461
    • (2003) Pharmacol. Rev. , vol.55 , pp. 425-461
    • Mizuno, N.1    Niwa, T.2    Yotsumoto, Y.3    Sugiyama, Y.4
  • 27
  • 28
    • 0031026780 scopus 로고    scopus 로고
    • Brain microvascular and astrocyte localization of P-glycoprotein
    • W.M. Pardridge, P.L. Golden, Y.S. Kang, and U. Bickel Brain microvascular and astrocyte localization of P-glycoprotein J. Neurochem. 68 1997 1278 1285
    • (1997) J. Neurochem. , vol.68 , pp. 1278-1285
    • Pardridge, W.M.1    Golden, P.L.2    Kang, Y.S.3    Bickel, U.4
  • 29
    • 0037665280 scopus 로고    scopus 로고
    • Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity
    • H. Potschka, M. Fedrowitz, and W. Loscher Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity J. Pharmacol. Exp. Ther. 306 2003 124 131
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 124-131
    • Potschka, H.1    Fedrowitz, M.2    Loscher, W.3
  • 30
    • 0031724003 scopus 로고    scopus 로고
    • Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells
    • A. Regina, A. Koman, M. Piciotti, B. El Hafny, M.S. Center, R. Bergmann, P.O. Couraud, and F. Roux Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells J. Neurochem. 71 1998 705 715
    • (1998) J. Neurochem. , vol.71 , pp. 705-715
    • Regina, A.1    Koman, A.2    Piciotti, M.3    El Hafny, B.4    Center, M.S.5    Bergmann, R.6    Couraud, P.O.7    Roux, F.8
  • 31
    • 0344980089 scopus 로고    scopus 로고
    • Dexamethasone regulation of P-glycoprotein activity in an immortalized rat brain endothelial cell line, GPNT
    • A. Regina, I.A. Romeo, J. Greenwood, P. Adamson, J.M. Bourre, P.O. Couraud, and F. Roux Dexamethasone regulation of P-glycoprotein activity in an immortalized rat brain endothelial cell line, GPNT J. Neurochem. 73 1999 1954 1963
    • (1999) J. Neurochem. , vol.73 , pp. 1954-1963
    • Regina, A.1    Romeo, I.A.2    Greenwood, J.3    Adamson, P.4    Bourre, J.M.5    Couraud, P.O.6    Roux, F.7
  • 32
    • 0034031326 scopus 로고    scopus 로고
    • Evidence for a constitutive, verapamil-sensitive, non-P-glycoprotein multidrug resistance phenotype in malignant glioma that is unaltered by radiochemotherapy in vivo
    • L. Rieger, J. Rieger, S. Winter, J. Streffer, P. Esser, J. Dichgans, R. Meyermann, and M. Weller Evidence for a constitutive, verapamil-sensitive, non-P-glycoprotein multidrug resistance phenotype in malignant glioma that is unaltered by radiochemotherapy in vivo Acta Neuropathol. 99 2000 555 562
    • (2000) Acta Neuropathol. , vol.99 , pp. 555-562
    • Rieger, L.1    Rieger, J.2    Winter, S.3    Streffer, J.4    Esser, P.5    Dichgans, J.6    Meyermann, R.7    Weller, M.8
  • 34
    • 0029892497 scopus 로고    scopus 로고
    • P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
    • A.H. Schinkel, E. Wagenaar, Caria A.A.M. Mol, and L. van Deemter P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs J. Clin. Invest. 97 1996 2517 2524
    • (1996) J. Clin. Invest. , vol.97 , pp. 2517-2524
    • Schinkel, A.H.1    Wagenaar, E.2    Mol Caria, A.A.M.3    Van Deemter, L.4
  • 35
    • 0033526176 scopus 로고    scopus 로고
    • P-glycoprotein, a gatekeeper in the blood-brain barrier
    • A.H. Schinkel P-glycoprotein, a gatekeeper in the blood-brain barrier Adv. Drug Deliv. Rev. 36 1999 179 194
    • (1999) Adv. Drug Deliv. Rev. , vol.36 , pp. 179-194
    • Schinkel, A.H.1
  • 36
    • 0036064611 scopus 로고    scopus 로고
    • Expression of the multidrug transporter P-glycoprotein in barin capillary endothelial cells and brain parenchyma of Amygdala-kindled rats
    • U. Seegers, H. Potschka, and W. Loscher Expression of the multidrug transporter P-glycoprotein in barin capillary endothelial cells and brain parenchyma of Amygdala-kindled rats Epilepsia 43 2002 675 684
    • (2002) Epilepsia , vol.43 , pp. 675-684
    • Seegers, U.1    Potschka, H.2    Loscher, W.3
  • 37
    • 0031891475 scopus 로고    scopus 로고
    • Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates
    • S. Seetharaman, M.A. Barrand, L. Maskell, and R.J. Scheper Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates J. Neurochem. 70 1998 1151 1159
    • (1998) J. Neurochem. , vol.70 , pp. 1151-1159
    • Seetharaman, S.1    Barrand, M.A.2    Maskell, L.3    Scheper, R.J.4
  • 38
    • 0036156280 scopus 로고    scopus 로고
    • Drug resistance in epilepsy: Expression of drug resistance proteins in common causes of refractory epilepsy
    • S.M. Sisodiya, W.R. Lin, B.N. Harding, M.V. Squier, and M. Thom Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy Brain 125 2002 22 31
    • (2002) Brain , vol.125 , pp. 22-31
    • Sisodiya, S.M.1    Lin, W.R.2    Harding, B.N.3    Squier, M.V.4    Thom, M.5
  • 39
    • 4644269603 scopus 로고    scopus 로고
    • Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy
    • M.A. Summers, J.L. Moore, and J.W. McAuley Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy Ann. Pharmacother. 10 2004 1631 1634
    • (2004) Ann. Pharmacother. , vol.10 , pp. 1631-1634
    • Summers, M.A.1    Moore, J.L.2    McAuley, J.W.3
  • 41
    • 0026669192 scopus 로고
    • Functional involvement of P-glycoprotein in blood-brain barrier
    • T. Tatsuta, M. Naito, T. Ohhara, I. Sugawara, and T. Tsurno Functional involvement of P-glycoprotein in blood-brain barrier J. Biol. Chem. 267 1992 20383 20391
    • (1992) J. Biol. Chem. , vol.267 , pp. 20383-20391
    • Tatsuta, T.1    Naito, M.2    Ohhara, T.3    Sugawara, I.4    Tsurno, T.5
  • 43
    • 0028179167 scopus 로고
    • New immunohistochemical "sandwich" staining method for mdr1 p-glycoprotein detection with JSB-1 monoclonal antibody in formalin-fixed, paraffin-embedded human tissues
    • K. Tóth, M.M. Vaughan, H.K. Slocum, M.A. Arredondo, H. Takita, R.M. Baker, and Y.M. Rustum New immunohistochemical "Sandwich" staining method for mdr1 p-glycoprotein detection with JSB-1 monoclonal antibody in formalin-fixed, paraffin-embedded human tissues Am. J. Pathol. 144 1994 227 236
    • (1994) Am. J. Pathol. , vol.144 , pp. 227-236
    • Tóth, K.1    Vaughan, M.M.2    Slocum, H.K.3    Arredondo, M.A.4    Takita, H.5    Baker, R.M.6    Rustum, Y.M.7
  • 44
    • 16344394610 scopus 로고    scopus 로고
    • Limbic system abnormalities associated with Ammon's horn sclerosis do not alter seizure outcome after amygdalohippocampectomy
    • H. Urbach, G. Siebenhaar, R. Koenig, J. von Oertzen, J. Scorzin, M. Kurthen, and H.H. Schild Limbic system abnormalities associated with Ammon's horn sclerosis do not alter seizure outcome after amygdalohippocampectomy Epilepsia 46 2005 549 555
    • (2005) Epilepsia , vol.46 , pp. 549-555
    • Urbach, H.1    Siebenhaar, G.2    Koenig, R.3    Von Oertzen, J.4    Scorzin, J.5    Kurthen, M.6    Schild, H.H.7
  • 45
    • 8444250735 scopus 로고    scopus 로고
    • Selective and persistent upregulation of mdr1b mRNA and P-glycoprotein in parahippocampal cortex of chronic epileptic rats
    • E. van Vilet, E. Aronica, S. Redeker, N. Marchi, M. Rizzi, A. Vezzani, and J. Gorter Selective and persistent upregulation of mdr1b mRNA and P-glycoprotein in parahippocampal cortex of chronic epileptic rats Epilepsy Res. 60 2004 203 213
    • (2004) Epilepsy Res. , vol.60 , pp. 203-213
    • Van Vilet, E.1    Aronica, E.2    Redeker, S.3    Marchi, N.4    Rizzi, M.5    Vezzani, A.6    Gorter, J.7
  • 46
    • 16244367423 scopus 로고    scopus 로고
    • Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables
    • H. Volk, H. Potschka, and W. Loscher Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables J. Histochem. Cytochem. 53 2005 517 531
    • (2005) J. Histochem. Cytochem. , vol.53 , pp. 517-531
    • Volk, H.1    Potschka, H.2    Loscher, W.3
  • 47
    • 0034937803 scopus 로고    scopus 로고
    • Downregulation of occludin expression in astrocytes by TNF is mediated via TNF type 1 receptor and nuclear factor-kB activation
    • M. Wachtel, M.F. Bolliger, H. Ishihara, K. Frei, H. Bluethmann, and S.M. Gloor Downregulation of occludin expression in astrocytes by TNF is mediated via TNF type 1 receptor and nuclear factor-kB activation J. Neurochem. 78 2001 155 162
    • (2001) J. Neurochem. , vol.78 , pp. 155-162
    • Wachtel, M.1    Bolliger, M.F.2    Ishihara, H.3    Frei, K.4    Bluethmann, H.5    Gloor, S.M.6
  • 48
    • 0037382694 scopus 로고    scopus 로고
    • Long-term seizure outcomes following amygdalohippocampectomy
    • H.G. Wieser, M. Ortega, A. Friedman, and Y. Yonekawa Long-term seizure outcomes following amygdalohippocampectomy J. Neurosurg. 98 2003 751 763
    • (2003) J. Neurosurg. , vol.98 , pp. 751-763
    • Wieser, H.G.1    Ortega, M.2    Friedman, A.3    Yonekawa, Y.4
  • 49
    • 0026442588 scopus 로고
    • A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy
    • A.R. Wyler, F.C. Dohan, J.B. Schweitzer, and A.D. Berry A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy J. Epilepsy 5 1992 220 225
    • (1992) J. Epilepsy , vol.5 , pp. 220-225
    • Wyler, A.R.1    Dohan, F.C.2    Schweitzer, J.B.3    Berry, A.D.4
  • 50
    • 0034623293 scopus 로고    scopus 로고
    • Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells
    • Y. Zhang, H. Han, W.F. Elmquist, and D.W. Miller Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells Brain Res. 876 2000 148 153
    • (2000) Brain Res. , vol.876 , pp. 148-153
    • Zhang, Y.1    Han, H.2    Elmquist, W.F.3    Miller, D.W.4
  • 51
    • 6344240461 scopus 로고    scopus 로고
    • Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells
    • Y. Zhang, J.D. Schuetz, W.F. Elmquist, and D.W. Miller Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells J. Pharmacol. Exp. Ther. 311 2004 449 455
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 449-455
    • Zhang, Y.1    Schuetz, J.D.2    Elmquist, W.F.3    Miller, D.W.4


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