-
1
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakacs G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM. Targeting multidrug resistance in cancer. Nat Rev Drug Discov 2006;5:219-234
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
2
-
-
43149118341
-
The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox)
-
Szakacs G, Varadi A, Ozvegy-Laczka C, Sarkadi B. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Drug Discov Today 2008;13:379-393
-
(2008)
Drug Discov Today
, vol.13
, pp. 379-393
-
-
Szakacs, G.1
Varadi, A.2
Ozvegy-Laczka, C.3
Sarkadi, B.4
-
3
-
-
62149113710
-
Relevance of multidrug resistance in the age of targeted therapy
-
Turk D, Szakacs G. Relevance of multidrug resistance in the age of targeted therapy. Curr Opin Drug Discov Devel 2009;12:246-252
-
(2009)
Curr Opin Drug Discov Devel
, vol.12
, pp. 246-252
-
-
Turk, D.1
Szakacs, G.2
-
4
-
-
0032836990
-
Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase
-
Nicholson KM, Quinn DM, Kellett GL, Warr JR. Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase. Br J Cancer 1999;81:423-430
-
(1999)
Br J Cancer
, vol.81
, pp. 423-430
-
-
Nicholson, K.M.1
Quinn, D.M.2
Kellett, G.L.3
Warr, J.R.4
-
5
-
-
0030898656
-
The human KB multidrug-resistant cell line KB-C1 is hypersensitive to inhibitors of glycosylation
-
DOI 10.1016/S0304-3835(97)04739-3, PII S0304383597047393
-
Bentley J, Quinn DM, Pitman RS, Warr JR, Kellett GL. The human KB multidrug-resistant cell line KB-C1 is hypersensitive to inhibitors of glycosylation. Cancer Lett 1997;115:221-227 (Pubitemid 27196609)
-
(1997)
Cancer Letters
, vol.115
, Issue.2
, pp. 221-227
-
-
Bentley, J.1
Quinn, D.M.2
Pitman, R.S.3
Warr, J.R.4
Kellett, G.L.5
-
6
-
-
0036045129
-
P-glycoprotein modulates ceramide- mediated sensitivity of human breast cancer cells to tubulin-binding anticancer drugs
-
Shabbits JA, Mayer LD. P-glycoprotein modulates ceramide- mediated sensitivity of human breast cancer cells to tubulin-binding anticancer drugs. Mol Cancer Ther 2002;1:205-213
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 205-213
-
-
Shabbits, J.A.1
Mayer, L.D.2
-
7
-
-
5144226566
-
Predicting drug sensitivity and resistance: Profiling ABC transporter genes in cancer cells
-
DOI 10.1016/j.ccr.2004.06.026, PII S1535610804002065
-
Szakacs G, Annereau JP, Lababidi S, et al. Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells. Cancer Cell 2004; 6:129-137 (Pubitemid 39485685)
-
(2004)
Cancer Cell
, vol.6
, Issue.2
, pp. 129-137
-
-
Szakacs, G.1
Annereau, J.-P.2
Lababidi, S.3
Shankavaram, U.4
Arciello, A.5
Bussey, K.J.6
Reinhold, W.7
Guo, Y.8
Kruh, G.D.9
Reimers, M.10
Weinstein, J.N.11
Gottesman, M.M.12
-
8
-
-
0028838239
-
Gain and loss of hypersensitivity to resistance modifiers in multidrug resistant Chinese hamster ovary cells
-
Warr JR, Quinn D, Elend M, Fenton JA. Gain and loss of hypersensitivity to resistance modifiers in multidrug resistant Chinese hamster ovary cells. Cancer Lett 1995; 98:115-120
-
(1995)
Cancer Lett
, vol.98
, pp. 115-120
-
-
Warr, J.R.1
Quinn, D.2
Elend, M.3
Fenton, J.A.4
-
9
-
-
0032980591
-
Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents
-
Lehne G, De Angelis P, den Boer M, Rugstad HE. Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents. Leukemia 1999;13: 768-778 (Pubitemid 29243629)
-
(1999)
Leukemia
, vol.13
, Issue.5
, pp. 768-778
-
-
Lehne, G.1
De Angelis, P.2
Den Boer, M.3
Rugstad, H.E.4
-
10
-
-
0036939821
-
The cyclosporin PSC 833 increases survival and delays engraftment of human multidrug-resistant leukemia cells in xenotransplanted NOD-SCID mice
-
DOI 10.1038/sj.leu.2402663
-
Lehne G, Sorensen DR, Tjonnfjord GE, et al. The cyclosporin PSC 833 increases survival and delays engraftment of human multidrug-resistant leukemia cells in xenotransplanted NOD-SCID mice. Leukemia 2002;16:2388-2394 (Pubitemid 36054372)
-
(2002)
Leukemia
, vol.16
, Issue.12
, pp. 2388-2394
-
-
Lehne, G.1
Sorensen, D.R.2
Tjonnfjord, G.E.3
Beiske, C.4
Hagve, T.-A.5
Rugstad, H.E.6
Clausen, O.P.F.7
-
11
-
-
0025774480
-
The multidrug resistance phenotype: 31P nuclear magnetic resonance characterization and 2-deoxyglucose toxicity
-
Kaplan O, Jaroszewski JW, Clarke R, et al. The multidrug resistance phenotype: 31P nuclear magnetic resonance characterization and 2-deoxyglucose toxicity. Cancer Res 1991;51:1638-1644
-
(1991)
Cancer Res
, vol.51
, pp. 1638-1644
-
-
Kaplan, O.1
Jaroszewski, J.W.2
Clarke, R.3
-
12
-
-
0031796023
-
2-Deoxy-D-glucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis
-
Bell SE, Quinn DM, Kellett GL, Warr JR. 2-Deoxy-D-glucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis. Br J Cancer 1998;78:1464-1470 (Pubitemid 28517543)
-
(1998)
British Journal of Cancer
, vol.78
, Issue.11
, pp. 1464-1470
-
-
Bell, S.E.1
Quinn, D.M.2
Kellett, G.L.3
Warr, J.R.4
-
13
-
-
0037049880
-
The preferential induction of apoptosis in multidrug-resistant KB cells by 5-fluorouracil
-
DOI 10.1016/S0304-3835(01)00721-2, PII S0304383501007212
-
Warr JR, Bamford A, Quinn DM. The preferential induction of apoptosis in multidrug-resistant KB cells by 5-fluorouracil. Cancer Lett 2002;175:39-44. (Pubitemid 33153042)
-
(2002)
Cancer Letters
, vol.175
, Issue.1
, pp. 39-44
-
-
Warr, J.R.1
Bamford, A.2
Quinn, D.M.3
-
14
-
-
0038235998
-
Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines
-
DOI 10.1038/sj.bjc.6601011
-
Bergman AM, Pinedo HM, Talianidis I, et al. Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines. Br J Cancer 2003;88: 1963-1970 (Pubitemid 36829675)
-
(2003)
British Journal of Cancer
, vol.88
, Issue.12
, pp. 1963-1970
-
-
Bergman, A.M.1
Pinedo, H.M.2
Talianidis, I.3
Veerman, G.4
Loves, W.J.P.5
Van Der Wilt, C.L.6
Peters, G.J.7
-
15
-
-
0031035181
-
An information-intensive approach to the molecular pharmacology of cancer
-
DOI 10.1126/science.275.5298.343
-
Weinstein JN, Myers TG, O'Connor PM, et al. An information-intensive approach to the molecular pharmacology of cancer. Science 1997;275:343-349 (Pubitemid 27051604)
-
(1997)
Science
, vol.275
, Issue.5298
, pp. 343-349
-
-
Weinstein, J.N.1
Myers, T.G.2
O'Connor, P.M.3
Friend, S.H.4
Fornace Jr., A.J.5
Kohn, K.W.6
Fojo, T.7
Bates, S.E.8
Rubinstein, L.V.9
Anderson, N.L.10
Buolamwini, J.K.11
Van Osdol, W.W.12
Monks, A.P.13
Scudiero, D.A.14
Sausville, E.A.15
Zaharevitz, D.W.16
Bunow, B.17
Viswanadhan, V.N.18
Johnson, G.S.19
Wittes, R.E.20
Paull, K.D.21
more..
-
16
-
-
0025775062
-
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
-
Monks A, Scudiero D, Skehan P, et al. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J Natl Cancer Inst 1991;83:757-766
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 757-766
-
-
Monks, A.1
Scudiero, D.2
Skehan, P.3
-
17
-
-
66249134216
-
Synthesis, Activity, and pharmacophore development for isatin- β-thiosemicarbazones with selective activity toward multidrug-resistant cells
-
Hall MD, Salam NK, Hellawell JL, et al. Synthesis, Activity, and pharmacophore development for isatin- β-thiosemicarbazones with selective activity toward multidrug-resistant cells. J Med Chem 2009;52: 3191-3204
-
(2009)
J Med Chem
, vol.52
, pp. 3191-3204
-
-
Hall, M.D.1
Salam, N.K.2
Hellawell, J.L.3
-
18
-
-
33646424730
-
Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer
-
Ludwig JA, Szakacs G, Martin SE, et al. Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer. Cancer Res 2006;66:4808-4815
-
(2006)
Cancer Res
, vol.66
, pp. 4808-4815
-
-
Ludwig, J.A.1
Szakacs, G.2
Martin, S.E.3
-
19
-
-
0023251054
-
Potential antitumor agents. 50. in vivo solid-tumor activity of derivatives of N-[2-(dimethylamino)ethyl] acridine-4-carboxamide
-
Atwell GJ, Rewcastle GW, Baguley BC, Denny WA. Potential antitumor agents. 50. In vivo solid-tumor activity of derivatives of N-[2-(dimethylamino) ethyl] acridine-4-carboxamide. J Med Chem 1987;30:664-669
-
(1987)
J Med Chem
, vol.30
, pp. 664-669
-
-
Atwell, G.J.1
Rewcastle, G.W.2
Baguley, B.C.3
Denny, W.A.4
-
20
-
-
37249035098
-
Chemical data mining of the NCI human tumor cell line database
-
DOI 10.1021/ci700141x
-
Wang H, Klinginsmith J, Dong X, et al. Chemical data mining of the NCI human tumor cell line database. J Chem Inf Model 2007;47:2063-2076 (Pubitemid 350275073)
-
(2007)
Journal of Chemical Information and Modeling
, vol.47
, Issue.6
, pp. 2063-2076
-
-
Wang, H.1
Klinginsmith, J.2
Dong, X.3
Lee, A.C.4
Guha, R.5
Wu, Y.6
Crippen, G.M.7
Wild, D.J.8
-
21
-
-
0023030685
-
Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins
-
Shen DW, Cardarelli C, Hwang J, et al. Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins. J Biol Chem 1986;261:7762-7770 (Pubitemid 17208699)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.17
, pp. 7762-7770
-
-
Ding-wu, S.1
Cardarelli, C.2
Hwang, J.3
-
22
-
-
0028964955
-
Differential effects of P-glycoprotein inhibitors on NIH3T3 cells transfected with wild-type (G185) or mutant (V185) multidrug transporters
-
Cardarelli CO, Aksentijevich I, Pastan I, Gottesman MM. Differential effects of P-glycoprotein inhibitors on NIH3T3 cells transfected with wild-type (G185) or mutant (V185) multidrug transporters. Cancer Res 1995;55:1086-1091
-
(1995)
Cancer Res
, vol.55
, pp. 1086-1091
-
-
Cardarelli, C.O.1
Aksentijevich, I.2
Pastan, I.3
Gottesman, M.M.4
-
23
-
-
0033921304
-
Lysosomal accumulation of drugs in drug-sensitive MES-SA but not multidrug-resistant MES-SA/Dx5 uterine sarcoma cells
-
DOI 10.1002/1097-4652(200008)184:2<263::AID-JCP15>3.0.CO;2-F
-
Wang E, Lee MD, Dunn KW. Lysosomal accumulation of drugs in drug-sensitive MES-SA but not multidrug- resistant MES-SA/Dx5 uterine sarcoma cells. J Cell Physiol 2000;184:263-274 (Pubitemid 30432319)
-
(2000)
Journal of Cellular Physiology
, vol.184
, Issue.2
, pp. 263-274
-
-
Wang, E.1
Lee, M.D.2
Dunn, K.W.3
-
24
-
-
0037335189
-
Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer to progenitor cells
-
DOI 10.1089/104303403321209005
-
Ujhelly O, Ozvegy C, Varady G, et al. Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer to progenitor cells. Hum Gene Ther 2003;14:403-412 (Pubitemid 36308359)
-
(2003)
Human Gene Therapy
, vol.14
, Issue.4
, pp. 403-412
-
-
Ujhelly, O.1
Ozvegy, C.2
Varady, G.3
Cervenak, J.4
Homolya, L.5
Grez, M.6
Scheffer, G.7
Roos, D.8
Bates, S.E.9
Varadi, A.10
Sarkadi, B.11
Nemet, K.12
-
25
-
-
0017357778
-
Studies on the reaction of 2 formylpyridine thiosemicarbazone and its iron and copper complexes with biological systems
-
Antholine W, Knight J, Whelan H, Petering DH. Studies of the reaction of 2-formylpyridine thiosemicarbazone and its iron and copper complexes with biological systems. Mol Pharmacol 1977;13:89-98. (Pubitemid 8027143)
-
(1977)
Molecular Pharmacology
, vol.13
, Issue.1
, pp. 89-98
-
-
Antholine, W.1
Knight, J.2
Whelan, H.3
Petering, D.H.4
-
26
-
-
0032832996
-
Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-ap): An inhibitor of ribonucleotide reductase with antineoplastic activity
-
PII S006525719800017X
-
Finch RA, Liu MC, Cory AH, Cory JG, Sartorelli AC. Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity. Adv Enzyme Regul 1999;39:3-12. (Pubitemid 129682485)
-
(1999)
Advances in Enzyme Regulation
, vol.39
, Issue.1
, pp. 3-12
-
-
Finch, R.A.1
Liu, M.-C.2
Cory, A.H.3
Cory, J.G.4
Sartorelli, A.C.5
-
27
-
-
0034537787
-
Cytotoxicity of copper and cobalt complexes of furfural semicarbazone and thiosemicarbazone derivatives in murine and human tumor cell lines
-
Hall IH, Lackey CB, Kistler TD, et al. Cytotoxicity of copper and cobalt complexes of furfural semicarbazone and thiosemicarbazone derivatives in murine and human tumor cell lines. Pharmazie 2000;55: 937-941
-
(2000)
Pharmazie
, vol.55
, pp. 937-941
-
-
Hall, I.H.1
Lackey, C.B.2
Kistler, T.D.3
-
28
-
-
0026510904
-
Interactions of 1,10-phenanthroline and its copper complex with Ehrlich cells
-
Byrnes RW, Antholine WE, Petering DH. Interactions of 1,10-phenanthroline and its copper complex with Ehrlich cells. Free Radic Biol Med 1992;12:457-469
-
(1992)
Free Radic Biol Med
, vol.12
, pp. 457-469
-
-
Byrnes, R.W.1
Antholine, W.E.2
Petering, D.H.3
-
29
-
-
0033032774
-
Synthesis and cytotoxicity evaluation of some 8-hydroxyquinoline derivatives
-
DOI 10.1211/0022357991772826
-
Shen AY, Wu SN, Chiu CT. Synthesis and cytotoxicity evaluation of some 8-hydroxyquinoline derivatives. J Pharm Pharmacol 1999;51:543-548 (Pubitemid 29319779)
-
(1999)
Journal of Pharmacy and Pharmacology
, vol.51
, Issue.5
, pp. 543-548
-
-
Shen, A.-Y.1
Wu, S.-N.2
Chiu, C.-T.3
-
31
-
-
14844293088
-
Anticancer metal compounds in NCI's tumor-screening database: Putative mode of action
-
DOI 10.1016/j.bcp.2005.01.001
-
Huang R, Wallqvist A, Covell DG. Anticancer metal compounds in NCI's tumor-screening database: putative mode of action. Biochem Pharmacol 2005;69:1009-1039 (Pubitemid 40349015)
-
(2005)
Biochemical Pharmacology
, vol.69
, Issue.7
, pp. 1009-1039
-
-
Huang, R.1
Wallqvist, A.2
Covell, D.G.3
-
32
-
-
0039392162
-
The crystal and molecular structures of isoperezone, aminoperezone, and isoaminoperezone: A comparative study of their crystal packing
-
Enriquez RG, Fernandez G. JM, Gnecco D, Penicaud A, Reynolds WF. The crystal and molecular structures of isoperezone, aminoperezone and isoaminoperezone: a comparative study of their crystal packing. J Chem Crystallogr 1998;28:529-537 (Pubitemid 128365359)
-
(1998)
Journal of Chemical Crystallography
, vol.28
, Issue.7
, pp. 529-537
-
-
Enriquez, R.G.1
Fernandez-G, J.M.2
Gnecco, D.3
Penicaud, A.4
Reynolds, W.F.5
-
33
-
-
0023525876
-
2+ releasing effect of perezone on adrenal cortex mitochondria
-
DOI 10.1016/0024-3205(87)90479-6
-
Cuellar A, Carabez A, Chavez E. Ca2+ releasing effect of perezone on adrenal cortex mitochondria. Life Sci 1987;41:2047-2054 (Pubitemid 18006134)
-
(1987)
Life Sciences
, vol.41
, Issue.17
, pp. 2047-2054
-
-
Cuellar, A.1
Carabez, A.2
Chavez, E.3
-
34
-
-
34447272264
-
Unifying mechanism for anticancer agents involving electron transfer and oxidative stress: Clinical implications
-
DOI 10.1016/j.mehy.2006.08.046, PII S0306987707001235
-
Kovacic P. Unifying mechanism for anticancer agents involving electron transfer and oxidative stress: clinical implications. Med Hypotheses 2007;69:510-516 (Pubitemid 47043281)
-
(2007)
Medical Hypotheses
, vol.69
, Issue.3
, pp. 510-516
-
-
Kovacic, P.1
-
35
-
-
16344377909
-
Correlating gene expression with chemical scaffolds of cytotoxic agents: Ellipticines as substrates and inhibitors of MDR1
-
DOI 10.1038/sj.tpj.6500297
-
Huang Y, Blower PE, Yang C, et al. Correlating gene expression with chemical scaffolds of cytotoxic agents: ellipticines as substrates and inhibitors of MDR1. Pharmacogenomics J 2005;5:112-125 (Pubitemid 40468118)
-
(2005)
Pharmacogenomics Journal
, vol.5
, Issue.2
, pp. 112-125
-
-
Huang, Y.1
Blower, P.E.2
Yang, C.3
Barbacioru, C.4
Dai, Z.5
Zhang, Y.6
Xiao, J.J.7
Chan, K.K.8
Sadee, W.9
-
36
-
-
33749011163
-
The NCI60 human tumour cell line anticancer drug screen
-
Shoemaker RH. The NCI60 human tumour cell line anticancer drug screen. Nat Rev Cancer 2006;6:813-823
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 813-823
-
-
Shoemaker, R.H.1
-
37
-
-
0037075063
-
Mining the National Cancer Institute's tumor-screening database: Identification of compounds with similar cellular activities
-
Rabow AA, Shoemaker RH, Sausville EA, Covell DG. Mining the National Cancer Institute's tumor-screening database: identification of compounds with similar cellular activities. J Med Chem 2002;45:818-840
-
(2002)
J Med Chem
, vol.45
, pp. 818-840
-
-
Rabow, A.A.1
Shoemaker, R.H.2
Sausville, E.A.3
Covell, D.G.4
-
38
-
-
33845753448
-
Chelators at the cancer coalface: Desferrioxamine to triapine and beyond
-
DOI 10.1158/1078-0432.CCR-06-1954
-
Yu Y, Wong J, Lovejoy DB, Kalinowski DS, Richardson DR. Chelators at the cancer coalface: desferrioxamine to Triapine and beyond. Clin Cancer Res 2006; 12:6876-6883 (Pubitemid 44974479)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.23
, pp. 6876-6883
-
-
Yu, Y.1
Wong, J.2
Lovejoy, D.B.3
Kalinowski, D.S.4
Richardson, D.R.5
-
39
-
-
34247616802
-
Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24)
-
Heffeter P, Jakupec MA, Korner W, et al. Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24). Biochem Pharmacol 2007;73:1873-1886.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 1873-1886
-
-
Heffeter, P.1
Jakupec, M.A.2
Korner, W.3
-
40
-
-
0031053478
-
Indomethacin mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein
-
Draper MP, Martell RL, Levy SB. Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein. Br J Cancer 1997;75: 810-815 (Pubitemid 27110695)
-
(1997)
British Journal of Cancer
, vol.75
, Issue.6
, pp. 810-815
-
-
Draper, M.P.1
Martell, R.L.2
Levy, S.B.3
-
41
-
-
0036050211
-
Pharmacogenomic analysis: Correlating molecular substructure classes with microarray gene expression data
-
DOI 10.1038/sj.tpj.6500116
-
Blower PE, Yang C, Fligner MA, et al. Pharmacogenomic analysis: correlatingmolecular substructure classes with microarray gene expression data. Pharmacogenomics J 2002;2:259-271 (Pubitemid 35023584)
-
(2002)
Pharmacogenomics Journal
, vol.2
, Issue.4
, pp. 259-271
-
-
Blower, P.E.1
Yang, C.2
Fligner, M.A.3
Verducci, J.S.4
Yu, L.5
Richman, S.6
Weinstein, J.N.7
-
42
-
-
33749515083
-
A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics
-
DOI 10.1073/pnas.0604979103
-
Whitnall M, Howard J, Ponka P, Richardson DR. A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics. Proc Natl Acad Sci U S A 2006;103: 14901-14906 (Pubitemid 44527826)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.40
, pp. 14901-14906
-
-
Whitnall, M.1
Howard, J.2
Ponka, P.3
Richardson, D.R.4
-
43
-
-
0026778383
-
Mechanism of action of hydroxyurea
-
Yarbro JW. Mechanism of action of hydroxyurea. Semin Oncol 1992;19:1-10.
-
(1992)
Semin Oncol
, vol.19
, pp. 1-10
-
-
Yarbro, J.W.1
-
44
-
-
34548541286
-
Bioreductive activation and drug chaperoning in cobalt pharmaceuticals
-
DOI 10.1039/b707121c
-
Hall MD, Failes TW, Yamamoto N, Hambley TW. Bioreductive activation and drug chaperoning in cobalt pharmaceuticals. Dalton Trans 2007:3983-3990 (Pubitemid 47384620)
-
(2007)
Dalton Transactions
, Issue.36
, pp. 3983-3990
-
-
Hall, M.D.1
Failes, T.W.2
Yamamoto, N.3
Hambley, T.W.4
-
45
-
-
0030869671
-
Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase
-
DOI 10.1016/S0006-2952(97)00210-4, PII S0006295297002104
-
Rappa G, Lorico A, Liu MC, et al. Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase. Biochem Pharmacol 1997;54:649-655 (Pubitemid 27404624)
-
(1997)
Biochemical Pharmacology
, vol.54
, Issue.6
, pp. 649-655
-
-
Rappa, G.1
Lorico, A.2
Liu, M.-C.3
Kruh, G.D.4
Cory, A.H.5
Cory, J.G.6
Sartorelli, A.C.7
-
46
-
-
60549103590
-
Iron chelators of the dipyr-idylketone thiosemicarbazone class: Precomplexation and transmetalation effects on anticancer activity
-
Bernhardt PV, Sharpe PC, Islam M, Lovejoy DB, Kalinowski DS, Richardson DR. Iron chelators of the dipyr-idylketone thiosemicarbazone class: precomplexation and transmetalation effects on anticancer activity. J Med Chem 2009;52:407-415
-
(2009)
J Med Chem
, vol.52
, pp. 407-415
-
-
Bernhardt, P.V.1
Sharpe, P.C.2
Islam, M.3
Lovejoy, D.B.4
Kalinowski, D.S.5
Richardson, D.R.6
|