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Volumn 69, Issue 21, 2009, Pages 8293-8301

Identification of compounds selectively killing multidrug-resistant cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPEREZONE; ANILINEPEREZONE; ANTINEOPLASTIC AGENT; ISOAMINOPEREZONE; NSC 10580; NSC 168468; NSC 292408; NSC 356777; NSC 403148; NSC 43320; NSC 641208; NSC 649816; NSC 651859; NSC 653864; NSC 672036; NSC 673999; NSC 681125; NSC 688942; NSC 693871; NSC 697120; NSC 697128; NSC 697135; NSC 697137; NSC 710857; NSC 713048; NSC 716765; NSC 716766; NSC 73306; NSC 86715; PEREZONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 70350537031     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-2422     Document Type: Article
Times cited : (94)

References (46)
  • 2
    • 43149118341 scopus 로고    scopus 로고
    • The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox)
    • Szakacs G, Varadi A, Ozvegy-Laczka C, Sarkadi B. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Drug Discov Today 2008;13:379-393
    • (2008) Drug Discov Today , vol.13 , pp. 379-393
    • Szakacs, G.1    Varadi, A.2    Ozvegy-Laczka, C.3    Sarkadi, B.4
  • 3
    • 62149113710 scopus 로고    scopus 로고
    • Relevance of multidrug resistance in the age of targeted therapy
    • Turk D, Szakacs G. Relevance of multidrug resistance in the age of targeted therapy. Curr Opin Drug Discov Devel 2009;12:246-252
    • (2009) Curr Opin Drug Discov Devel , vol.12 , pp. 246-252
    • Turk, D.1    Szakacs, G.2
  • 4
    • 0032836990 scopus 로고    scopus 로고
    • Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase
    • Nicholson KM, Quinn DM, Kellett GL, Warr JR. Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase. Br J Cancer 1999;81:423-430
    • (1999) Br J Cancer , vol.81 , pp. 423-430
    • Nicholson, K.M.1    Quinn, D.M.2    Kellett, G.L.3    Warr, J.R.4
  • 5
    • 0030898656 scopus 로고    scopus 로고
    • The human KB multidrug-resistant cell line KB-C1 is hypersensitive to inhibitors of glycosylation
    • DOI 10.1016/S0304-3835(97)04739-3, PII S0304383597047393
    • Bentley J, Quinn DM, Pitman RS, Warr JR, Kellett GL. The human KB multidrug-resistant cell line KB-C1 is hypersensitive to inhibitors of glycosylation. Cancer Lett 1997;115:221-227 (Pubitemid 27196609)
    • (1997) Cancer Letters , vol.115 , Issue.2 , pp. 221-227
    • Bentley, J.1    Quinn, D.M.2    Pitman, R.S.3    Warr, J.R.4    Kellett, G.L.5
  • 6
    • 0036045129 scopus 로고    scopus 로고
    • P-glycoprotein modulates ceramide- mediated sensitivity of human breast cancer cells to tubulin-binding anticancer drugs
    • Shabbits JA, Mayer LD. P-glycoprotein modulates ceramide- mediated sensitivity of human breast cancer cells to tubulin-binding anticancer drugs. Mol Cancer Ther 2002;1:205-213
    • (2002) Mol Cancer Ther , vol.1 , pp. 205-213
    • Shabbits, J.A.1    Mayer, L.D.2
  • 8
    • 0028838239 scopus 로고
    • Gain and loss of hypersensitivity to resistance modifiers in multidrug resistant Chinese hamster ovary cells
    • Warr JR, Quinn D, Elend M, Fenton JA. Gain and loss of hypersensitivity to resistance modifiers in multidrug resistant Chinese hamster ovary cells. Cancer Lett 1995; 98:115-120
    • (1995) Cancer Lett , vol.98 , pp. 115-120
    • Warr, J.R.1    Quinn, D.2    Elend, M.3    Fenton, J.A.4
  • 9
    • 0032980591 scopus 로고    scopus 로고
    • Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents
    • Lehne G, De Angelis P, den Boer M, Rugstad HE. Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents. Leukemia 1999;13: 768-778 (Pubitemid 29243629)
    • (1999) Leukemia , vol.13 , Issue.5 , pp. 768-778
    • Lehne, G.1    De Angelis, P.2    Den Boer, M.3    Rugstad, H.E.4
  • 10
    • 0036939821 scopus 로고    scopus 로고
    • The cyclosporin PSC 833 increases survival and delays engraftment of human multidrug-resistant leukemia cells in xenotransplanted NOD-SCID mice
    • DOI 10.1038/sj.leu.2402663
    • Lehne G, Sorensen DR, Tjonnfjord GE, et al. The cyclosporin PSC 833 increases survival and delays engraftment of human multidrug-resistant leukemia cells in xenotransplanted NOD-SCID mice. Leukemia 2002;16:2388-2394 (Pubitemid 36054372)
    • (2002) Leukemia , vol.16 , Issue.12 , pp. 2388-2394
    • Lehne, G.1    Sorensen, D.R.2    Tjonnfjord, G.E.3    Beiske, C.4    Hagve, T.-A.5    Rugstad, H.E.6    Clausen, O.P.F.7
  • 11
    • 0025774480 scopus 로고
    • The multidrug resistance phenotype: 31P nuclear magnetic resonance characterization and 2-deoxyglucose toxicity
    • Kaplan O, Jaroszewski JW, Clarke R, et al. The multidrug resistance phenotype: 31P nuclear magnetic resonance characterization and 2-deoxyglucose toxicity. Cancer Res 1991;51:1638-1644
    • (1991) Cancer Res , vol.51 , pp. 1638-1644
    • Kaplan, O.1    Jaroszewski, J.W.2    Clarke, R.3
  • 12
    • 0031796023 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis
    • Bell SE, Quinn DM, Kellett GL, Warr JR. 2-Deoxy-D-glucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis. Br J Cancer 1998;78:1464-1470 (Pubitemid 28517543)
    • (1998) British Journal of Cancer , vol.78 , Issue.11 , pp. 1464-1470
    • Bell, S.E.1    Quinn, D.M.2    Kellett, G.L.3    Warr, J.R.4
  • 13
    • 0037049880 scopus 로고    scopus 로고
    • The preferential induction of apoptosis in multidrug-resistant KB cells by 5-fluorouracil
    • DOI 10.1016/S0304-3835(01)00721-2, PII S0304383501007212
    • Warr JR, Bamford A, Quinn DM. The preferential induction of apoptosis in multidrug-resistant KB cells by 5-fluorouracil. Cancer Lett 2002;175:39-44. (Pubitemid 33153042)
    • (2002) Cancer Letters , vol.175 , Issue.1 , pp. 39-44
    • Warr, J.R.1    Bamford, A.2    Quinn, D.M.3
  • 16
    • 0025775062 scopus 로고
    • Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
    • Monks A, Scudiero D, Skehan P, et al. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J Natl Cancer Inst 1991;83:757-766
    • (1991) J Natl Cancer Inst , vol.83 , pp. 757-766
    • Monks, A.1    Scudiero, D.2    Skehan, P.3
  • 17
    • 66249134216 scopus 로고    scopus 로고
    • Synthesis, Activity, and pharmacophore development for isatin- β-thiosemicarbazones with selective activity toward multidrug-resistant cells
    • Hall MD, Salam NK, Hellawell JL, et al. Synthesis, Activity, and pharmacophore development for isatin- β-thiosemicarbazones with selective activity toward multidrug-resistant cells. J Med Chem 2009;52: 3191-3204
    • (2009) J Med Chem , vol.52 , pp. 3191-3204
    • Hall, M.D.1    Salam, N.K.2    Hellawell, J.L.3
  • 18
    • 33646424730 scopus 로고    scopus 로고
    • Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer
    • Ludwig JA, Szakacs G, Martin SE, et al. Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer. Cancer Res 2006;66:4808-4815
    • (2006) Cancer Res , vol.66 , pp. 4808-4815
    • Ludwig, J.A.1    Szakacs, G.2    Martin, S.E.3
  • 19
    • 0023251054 scopus 로고
    • Potential antitumor agents. 50. in vivo solid-tumor activity of derivatives of N-[2-(dimethylamino)ethyl] acridine-4-carboxamide
    • Atwell GJ, Rewcastle GW, Baguley BC, Denny WA. Potential antitumor agents. 50. In vivo solid-tumor activity of derivatives of N-[2-(dimethylamino) ethyl] acridine-4-carboxamide. J Med Chem 1987;30:664-669
    • (1987) J Med Chem , vol.30 , pp. 664-669
    • Atwell, G.J.1    Rewcastle, G.W.2    Baguley, B.C.3    Denny, W.A.4
  • 21
    • 0023030685 scopus 로고
    • Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins
    • Shen DW, Cardarelli C, Hwang J, et al. Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins. J Biol Chem 1986;261:7762-7770 (Pubitemid 17208699)
    • (1986) Journal of Biological Chemistry , vol.261 , Issue.17 , pp. 7762-7770
    • Ding-wu, S.1    Cardarelli, C.2    Hwang, J.3
  • 22
    • 0028964955 scopus 로고
    • Differential effects of P-glycoprotein inhibitors on NIH3T3 cells transfected with wild-type (G185) or mutant (V185) multidrug transporters
    • Cardarelli CO, Aksentijevich I, Pastan I, Gottesman MM. Differential effects of P-glycoprotein inhibitors on NIH3T3 cells transfected with wild-type (G185) or mutant (V185) multidrug transporters. Cancer Res 1995;55:1086-1091
    • (1995) Cancer Res , vol.55 , pp. 1086-1091
    • Cardarelli, C.O.1    Aksentijevich, I.2    Pastan, I.3    Gottesman, M.M.4
  • 23
    • 0033921304 scopus 로고    scopus 로고
    • Lysosomal accumulation of drugs in drug-sensitive MES-SA but not multidrug-resistant MES-SA/Dx5 uterine sarcoma cells
    • DOI 10.1002/1097-4652(200008)184:2<263::AID-JCP15>3.0.CO;2-F
    • Wang E, Lee MD, Dunn KW. Lysosomal accumulation of drugs in drug-sensitive MES-SA but not multidrug- resistant MES-SA/Dx5 uterine sarcoma cells. J Cell Physiol 2000;184:263-274 (Pubitemid 30432319)
    • (2000) Journal of Cellular Physiology , vol.184 , Issue.2 , pp. 263-274
    • Wang, E.1    Lee, M.D.2    Dunn, K.W.3
  • 25
    • 0017357778 scopus 로고
    • Studies on the reaction of 2 formylpyridine thiosemicarbazone and its iron and copper complexes with biological systems
    • Antholine W, Knight J, Whelan H, Petering DH. Studies of the reaction of 2-formylpyridine thiosemicarbazone and its iron and copper complexes with biological systems. Mol Pharmacol 1977;13:89-98. (Pubitemid 8027143)
    • (1977) Molecular Pharmacology , vol.13 , Issue.1 , pp. 89-98
    • Antholine, W.1    Knight, J.2    Whelan, H.3    Petering, D.H.4
  • 26
    • 0032832996 scopus 로고    scopus 로고
    • Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-ap): An inhibitor of ribonucleotide reductase with antineoplastic activity
    • PII S006525719800017X
    • Finch RA, Liu MC, Cory AH, Cory JG, Sartorelli AC. Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity. Adv Enzyme Regul 1999;39:3-12. (Pubitemid 129682485)
    • (1999) Advances in Enzyme Regulation , vol.39 , Issue.1 , pp. 3-12
    • Finch, R.A.1    Liu, M.-C.2    Cory, A.H.3    Cory, J.G.4    Sartorelli, A.C.5
  • 27
    • 0034537787 scopus 로고    scopus 로고
    • Cytotoxicity of copper and cobalt complexes of furfural semicarbazone and thiosemicarbazone derivatives in murine and human tumor cell lines
    • Hall IH, Lackey CB, Kistler TD, et al. Cytotoxicity of copper and cobalt complexes of furfural semicarbazone and thiosemicarbazone derivatives in murine and human tumor cell lines. Pharmazie 2000;55: 937-941
    • (2000) Pharmazie , vol.55 , pp. 937-941
    • Hall, I.H.1    Lackey, C.B.2    Kistler, T.D.3
  • 28
    • 0026510904 scopus 로고
    • Interactions of 1,10-phenanthroline and its copper complex with Ehrlich cells
    • Byrnes RW, Antholine WE, Petering DH. Interactions of 1,10-phenanthroline and its copper complex with Ehrlich cells. Free Radic Biol Med 1992;12:457-469
    • (1992) Free Radic Biol Med , vol.12 , pp. 457-469
    • Byrnes, R.W.1    Antholine, W.E.2    Petering, D.H.3
  • 29
    • 0033032774 scopus 로고    scopus 로고
    • Synthesis and cytotoxicity evaluation of some 8-hydroxyquinoline derivatives
    • DOI 10.1211/0022357991772826
    • Shen AY, Wu SN, Chiu CT. Synthesis and cytotoxicity evaluation of some 8-hydroxyquinoline derivatives. J Pharm Pharmacol 1999;51:543-548 (Pubitemid 29319779)
    • (1999) Journal of Pharmacy and Pharmacology , vol.51 , Issue.5 , pp. 543-548
    • Shen, A.-Y.1    Wu, S.-N.2    Chiu, C.-T.3
  • 31
    • 14844293088 scopus 로고    scopus 로고
    • Anticancer metal compounds in NCI's tumor-screening database: Putative mode of action
    • DOI 10.1016/j.bcp.2005.01.001
    • Huang R, Wallqvist A, Covell DG. Anticancer metal compounds in NCI's tumor-screening database: putative mode of action. Biochem Pharmacol 2005;69:1009-1039 (Pubitemid 40349015)
    • (2005) Biochemical Pharmacology , vol.69 , Issue.7 , pp. 1009-1039
    • Huang, R.1    Wallqvist, A.2    Covell, D.G.3
  • 32
    • 0039392162 scopus 로고    scopus 로고
    • The crystal and molecular structures of isoperezone, aminoperezone, and isoaminoperezone: A comparative study of their crystal packing
    • Enriquez RG, Fernandez G. JM, Gnecco D, Penicaud A, Reynolds WF. The crystal and molecular structures of isoperezone, aminoperezone and isoaminoperezone: a comparative study of their crystal packing. J Chem Crystallogr 1998;28:529-537 (Pubitemid 128365359)
    • (1998) Journal of Chemical Crystallography , vol.28 , Issue.7 , pp. 529-537
    • Enriquez, R.G.1    Fernandez-G, J.M.2    Gnecco, D.3    Penicaud, A.4    Reynolds, W.F.5
  • 33
    • 0023525876 scopus 로고
    • 2+ releasing effect of perezone on adrenal cortex mitochondria
    • DOI 10.1016/0024-3205(87)90479-6
    • Cuellar A, Carabez A, Chavez E. Ca2+ releasing effect of perezone on adrenal cortex mitochondria. Life Sci 1987;41:2047-2054 (Pubitemid 18006134)
    • (1987) Life Sciences , vol.41 , Issue.17 , pp. 2047-2054
    • Cuellar, A.1    Carabez, A.2    Chavez, E.3
  • 34
    • 34447272264 scopus 로고    scopus 로고
    • Unifying mechanism for anticancer agents involving electron transfer and oxidative stress: Clinical implications
    • DOI 10.1016/j.mehy.2006.08.046, PII S0306987707001235
    • Kovacic P. Unifying mechanism for anticancer agents involving electron transfer and oxidative stress: clinical implications. Med Hypotheses 2007;69:510-516 (Pubitemid 47043281)
    • (2007) Medical Hypotheses , vol.69 , Issue.3 , pp. 510-516
    • Kovacic, P.1
  • 36
    • 33749011163 scopus 로고    scopus 로고
    • The NCI60 human tumour cell line anticancer drug screen
    • Shoemaker RH. The NCI60 human tumour cell line anticancer drug screen. Nat Rev Cancer 2006;6:813-823
    • (2006) Nat Rev Cancer , vol.6 , pp. 813-823
    • Shoemaker, R.H.1
  • 37
    • 0037075063 scopus 로고    scopus 로고
    • Mining the National Cancer Institute's tumor-screening database: Identification of compounds with similar cellular activities
    • Rabow AA, Shoemaker RH, Sausville EA, Covell DG. Mining the National Cancer Institute's tumor-screening database: identification of compounds with similar cellular activities. J Med Chem 2002;45:818-840
    • (2002) J Med Chem , vol.45 , pp. 818-840
    • Rabow, A.A.1    Shoemaker, R.H.2    Sausville, E.A.3    Covell, D.G.4
  • 38
    • 33845753448 scopus 로고    scopus 로고
    • Chelators at the cancer coalface: Desferrioxamine to triapine and beyond
    • DOI 10.1158/1078-0432.CCR-06-1954
    • Yu Y, Wong J, Lovejoy DB, Kalinowski DS, Richardson DR. Chelators at the cancer coalface: desferrioxamine to Triapine and beyond. Clin Cancer Res 2006; 12:6876-6883 (Pubitemid 44974479)
    • (2006) Clinical Cancer Research , vol.12 , Issue.23 , pp. 6876-6883
    • Yu, Y.1    Wong, J.2    Lovejoy, D.B.3    Kalinowski, D.S.4    Richardson, D.R.5
  • 39
    • 34247616802 scopus 로고    scopus 로고
    • Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24)
    • Heffeter P, Jakupec MA, Korner W, et al. Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24). Biochem Pharmacol 2007;73:1873-1886.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1873-1886
    • Heffeter, P.1    Jakupec, M.A.2    Korner, W.3
  • 40
    • 0031053478 scopus 로고    scopus 로고
    • Indomethacin mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein
    • Draper MP, Martell RL, Levy SB. Indomethacin-mediated reversal of multidrug resistance and drug efflux in human and murine cell lines overexpressing MRP, but not P-glycoprotein. Br J Cancer 1997;75: 810-815 (Pubitemid 27110695)
    • (1997) British Journal of Cancer , vol.75 , Issue.6 , pp. 810-815
    • Draper, M.P.1    Martell, R.L.2    Levy, S.B.3
  • 43
    • 0026778383 scopus 로고
    • Mechanism of action of hydroxyurea
    • Yarbro JW. Mechanism of action of hydroxyurea. Semin Oncol 1992;19:1-10.
    • (1992) Semin Oncol , vol.19 , pp. 1-10
    • Yarbro, J.W.1
  • 44
    • 34548541286 scopus 로고    scopus 로고
    • Bioreductive activation and drug chaperoning in cobalt pharmaceuticals
    • DOI 10.1039/b707121c
    • Hall MD, Failes TW, Yamamoto N, Hambley TW. Bioreductive activation and drug chaperoning in cobalt pharmaceuticals. Dalton Trans 2007:3983-3990 (Pubitemid 47384620)
    • (2007) Dalton Transactions , Issue.36 , pp. 3983-3990
    • Hall, M.D.1    Failes, T.W.2    Yamamoto, N.3    Hambley, T.W.4
  • 45
    • 0030869671 scopus 로고    scopus 로고
    • Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase
    • DOI 10.1016/S0006-2952(97)00210-4, PII S0006295297002104
    • Rappa G, Lorico A, Liu MC, et al. Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase. Biochem Pharmacol 1997;54:649-655 (Pubitemid 27404624)
    • (1997) Biochemical Pharmacology , vol.54 , Issue.6 , pp. 649-655
    • Rappa, G.1    Lorico, A.2    Liu, M.-C.3    Kruh, G.D.4    Cory, A.H.5    Cory, J.G.6    Sartorelli, A.C.7
  • 46
    • 60549103590 scopus 로고    scopus 로고
    • Iron chelators of the dipyr-idylketone thiosemicarbazone class: Precomplexation and transmetalation effects on anticancer activity
    • Bernhardt PV, Sharpe PC, Islam M, Lovejoy DB, Kalinowski DS, Richardson DR. Iron chelators of the dipyr-idylketone thiosemicarbazone class: precomplexation and transmetalation effects on anticancer activity. J Med Chem 2009;52:407-415
    • (2009) J Med Chem , vol.52 , pp. 407-415
    • Bernhardt, P.V.1    Sharpe, P.C.2    Islam, M.3    Lovejoy, D.B.4    Kalinowski, D.S.5    Richardson, D.R.6


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