-
3
-
-
0031590708
-
Changes in the ageing brain in health and disease
-
Anderton BH. Changes in the ageing brain in health and disease. Philos Trans R Soc Lond B Biol Sci 1997; 352: 1781-1792
-
(1997)
Philos Trans R Soc Lond B Biol Sci
, vol.352
, pp. 1781-1792
-
-
Anderton, B.H.1
-
4
-
-
0027164617
-
Regionally specific loss of neurones in the aging human hippocampus
-
West MJ. Regionally specific loss of neurones in the aging human hippocampus. Neurobiol Aging 1993; 14: 287-293
-
(1993)
Neurobiol Aging
, vol.14
, pp. 287-293
-
-
West, M.J.1
-
5
-
-
0025283380
-
Morphological adaptive response of the synaptic junctional zones in the human dentate gyrus during aging and Alzheimer's disease
-
Bertoni-Freddari C, Fattoretti P, Casoli T, Meier-Ruge W, Ulrich J. Morphological adaptive response of the synaptic junctional zones in the human dentate gyrus during aging and Alzheimer's disease. Brain Res 1990; 517: 69-75.
-
(1990)
Brain Res
, vol.517
, pp. 69-75
-
-
Bertoni-Freddari, C.1
Fattoretti, P.2
Casoli, T.3
Meier-Ruge, W.4
Ulrich, J.5
-
6
-
-
0027390458
-
Quantitative synaptic alterations in the human neocortex during normal aging
-
Masliah E, Mallory M, Hansen L, De Teresa R, Terry RD. Quantitative synaptic alterations in the human neocortex during normal aging. Neurology 1993; 43: 192-197
-
(1993)
Neurology
, vol.43
, pp. 192-197
-
-
Masliah, E.1
Mallory, M.2
Hansen, L.3
De Teresa, R.4
Terry, R.D.5
-
7
-
-
0028927265
-
Aging-related changes in rat striatal D2 receptor mRNA-containing neurons: A quantitative nonradioactive in situ hybridization study
-
Zhang L, Ravipati A, Joseph J, Roth GS. Aging-related changes in rat striatal D2 receptor mRNA-containing neurons: a quantitative nonradioactive in situ hybridization study. J Neurosci 1995; 15: 1735-1740
-
(1995)
J Neurosci
, vol.15
, pp. 1735-1740
-
-
Zhang, L.1
Ravipati, A.2
Joseph, J.3
Roth, G.S.4
-
8
-
-
77950258784
-
Monoamines
-
Squire LR, Ed. Oxford: Oxford Academic Press
-
Govoni S. Monoamines. In: Squire LR, Ed. Encyclopedia of Neuroscience. Oxford: Oxford Academic Press 2009; vol.5: pp. 931-937
-
(2009)
Encyclopedia of Neuroscience
, vol.5
, pp. 931-937
-
-
Govoni, S.1
-
9
-
-
35549001333
-
Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity
-
Sibille E, Su J, Leman S, Le Guisquet AM, Ibarguen-Vargas Y, Joeyen-Waldorf J, et al. Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity. Mol Psychiatry 2007; 12: 1042-1056
-
(2007)
Mol Psychiatry
, vol.12
, pp. 1042-1056
-
-
Sibille, E.1
Su, J.2
Leman, S.3
Le Guisquet, A.M.4
Ibarguen-Vargas, Y.5
Joeyen-Waldorf, J.6
-
10
-
-
0029240533
-
Changes in protein kinases in brain aging and Alzheimer's disease. Implications for drug therapy
-
Jin LW, Saitoh T. Changes in protein kinases in brain aging and Alzheimer's disease. Implications for drug therapy. Drugs Aging 1995; 6: 136-149
-
(1995)
Drugs Aging
, vol.6
, pp. 136-149
-
-
Jin, L.W.1
Saitoh, T.2
-
11
-
-
0026636023
-
Calcium as sculptor and destroyer of neural circuitry
-
Mattson MP. Calcium as sculptor and destroyer of neural circuitry. Exp Gerontol 1992; 27: 29-49.
-
(1992)
Exp Gerontol
, vol.27
, pp. 29-49
-
-
Mattson, M.P.1
-
12
-
-
33645450459
-
Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release
-
Gant JC, Sama MM, Landfield PW, Thibault O. Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release. J Neurosci 2006; 26: 3482-3490
-
(2006)
J Neurosci
, vol.26
, pp. 3482-3490
-
-
Gant, J.C.1
Sama, M.M.2
Landfield, P.W.3
Thibault, O.4
-
13
-
-
0000847978
-
Gene-expression profile of the ageing brain in mice
-
Lee CK, Weindruch R, Prolla TA. Gene-expression profile of the ageing brain in mice. Nat Genet 2000; 25: 294-297
-
(2000)
Nat Genet
, vol.25
, pp. 294-297
-
-
Lee, C.K.1
Weindruch, R.2
Prolla, T.A.3
-
14
-
-
3042631024
-
Gene regulation and DNA damage in the ageing human brain
-
Lu T, Pan Y, Kao SY, Li C, Kohane I, Chan J, et al. Gene regulation and DNA damage in the ageing human brain. Nature 2004; 429: 883-891
-
(2004)
Nature
, vol.429
, pp. 883-891
-
-
Lu, T.1
Pan, Y.2
Kao, S.Y.3
Li, C.4
Kohane, I.5
Chan, J.6
-
15
-
-
38949175007
-
A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging
-
Miller JA, Oldham MC, Geschwind DH. A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging. J Neurosci 2008; 28: 1410-1420
-
(2008)
J Neurosci
, vol.28
, pp. 1410-1420
-
-
Miller, J.A.1
Oldham, M.C.2
Geschwind, D.H.3
-
16
-
-
0038206578
-
Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment
-
Blalock EM, Chen KC, Sharrow K, Herman JP, Porter NM, Foster TC, et al. Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci 2003; 23: 3807-3819
-
(2003)
J Neurosci
, vol.23
, pp. 3807-3819
-
-
Blalock, E.M.1
Chen, K.C.2
Sharrow, K.3
Herman, J.P.4
Porter, N.M.5
Foster, T.C.6
-
17
-
-
33845293444
-
Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease
-
Brooks WM, Lynch PJ, Ingle CC, Hatton A, Emson PC, Faull RL, et al. Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease. Brain Res 2007; 1127: 127-135
-
(2007)
Brain Res
, vol.1127
, pp. 127-135
-
-
Brooks, W.M.1
Lynch, P.J.2
Ingle, C.C.3
Hatton, A.4
Emson, P.C.5
Faull, R.L.6
-
19
-
-
77956813083
-
Neurotrophic factor and cytokine signaling in the aging brain
-
Mattson MP, Geddes JW, Ed. Greenwich, CT: JAI
-
Mattson MP, Lindvall O. Neurotrophic factor and cytokine signaling in the aging brain. In: Mattson MP, Geddes JW, Ed. The Aging Brain. Greenwich, CT: JAI 1997; pp. 299-345.
-
(1997)
The Aging Brain
, pp. 299-345
-
-
Mattson, M.P.1
Lindvall, O.2
-
20
-
-
33747172771
-
Mechanisms of neurotrophin receptor signalling
-
Zampieri N, Chao MV. Mechanisms of neurotrophin receptor signalling. Biochem Soc Trans 2006; 34: 607-611
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 607-611
-
-
Zampieri, N.1
Chao, M.V.2
-
21
-
-
17644416779
-
Therapeutic potential of neurotrophic factors in neurodegenerative diseases
-
Levy YS, Gilgun-Sherki Y, Melamed E, Offen D. Therapeutic potential of neurotrophic factors in neurodegenerative diseases. Bio Drugs 2005; 19: 97-127.
-
(2005)
Bio Drugs
, vol.19
, pp. 97-127
-
-
Levy, Y.S.1
Gilgun-Sherki, Y.2
Melamed, E.3
Offen, D.4
-
22
-
-
41149180869
-
Synaptic plasticity-regulated gene expression: A key event in the long-lasting changes of neuronal function
-
Tabuchi A. Synaptic plasticity-regulated gene expression: a key event in the long-lasting changes of neuronal function. Biol Pharm Bull 2008; 31: 327-335
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 327-335
-
-
Tabuchi, A.1
-
23
-
-
0034086877
-
Neurotrophic factor strategies for the treatment of Alzheimer disease
-
Nabeshima T, Yamada K. Neurotrophic factor strategies for the treatment of Alzheimer disease. Alzheimer Dis Assoc Disord 2000; 14: S39-S46.
-
(2000)
Alzheimer Dis Assoc Disord
, vol.14
-
-
Nabeshima, T.1
Yamada, K.2
-
25
-
-
64549141182
-
Development of a non invasive NGF-based therapy for Alzheimer's disease
-
Covaceuszach S, Capsoni S, Ugolini G, Spirito F, Vignone D, Cattaneo A. Development of a non invasive NGF-based therapy for Alzheimer's disease. Curr Alzheimer Res 2009; 6:158-170
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 158-170
-
-
Covaceuszach, S.1
Capsoni, S.2
Ugolini, G.3
Spirito, F.4
Vignone, D.5
Cattaneo, A.6
-
26
-
-
33845577779
-
The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease
-
Cole GM, Frautschy SA. The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease. Exp Gerontol 2007; 42: 10-21.
-
(2007)
Exp Gerontol
, vol.42
, pp. 10-21
-
-
Cole, G.M.1
Frautschy, S.A.2
-
27
-
-
0142026832
-
Potential roles of insulin and IGF-1 in Alzheimer's disease
-
Gasparini L, Xu H. Potential roles of insulin and IGF-1 in Alzheimer's disease. Trends Neurosci 2003; 26: 404-406
-
(2003)
Trends Neurosci
, vol.26
, pp. 404-406
-
-
Gasparini, L.1
Xu, H.2
-
28
-
-
41149120252
-
Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease
-
Zuccato C, Marullo M, Conforti P, MacDonald ME, Tartari M, Cattaneo E. Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease. Brain Pathol 2008; 18: 225-238
-
(2008)
Brain Pathol
, vol.18
, pp. 225-238
-
-
Zuccato, C.1
Marullo, M.2
Conforti, P.3
MacDonald, M.E.4
Tartari, M.5
Cattaneo, E.6
-
29
-
-
56649124807
-
Glutamate and neurotrophic factors in neuronal plasticity and disease
-
Mattson MP. Glutamate and neurotrophic factors in neuronal plasticity and disease. Ann NY Acad Sci 2008; 1144: 97-112.
-
(2008)
Ann NY Acad Sci
, vol.1144
, pp. 97-112
-
-
Mattson, M.P.1
-
30
-
-
41149162712
-
Progress in neuroprotective strategies for preventing epilepsy
-
Acharya MM, Hattiangady B, Shetty AK. Progress in neuroprotective strategies for preventing epilepsy. Prog Neurobiol 2008; 84: 363-404.
-
(2008)
Prog Neurobiol
, vol.84
, pp. 363-404
-
-
Acharya, M.M.1
Hattiangady, B.2
Shetty, A.K.3
-
31
-
-
0029830402
-
Structural determinants of Trk receptor specificities using BDNF-based neurotrophin chimeras
-
Lai KO, Glass DJ, Geis D, Yancopoulos GD, Ip NY. Structural determinants of Trk receptor specificities using BDNF-based neurotrophin chimeras. J Neurosci Res 1996; 46: 618-629
-
(1996)
J Neurosci Res
, vol.46
, pp. 618-629
-
-
Lai, K.O.1
Glass, D.J.2
Geis, D.3
Yancopoulos, G.D.4
Ip, N.Y.5
-
32
-
-
0033635904
-
Neurotrophin signal transduction in the nervous system
-
Bibel M, Barde YA. Neurotrophin signal transduction in the nervous system. Genes Dev 2000; 14: 2919-2957
-
(2000)
Genes Dev
, vol.14
, pp. 2919-2957
-
-
Bibel, M.1
Barde, Y.A.2
-
33
-
-
0033081041
-
Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding
-
Munck Petersen C, Nielsen MS, Jacobsen C, Tauris J, Jacobsen L, Gliemann J, et al. Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding. EMBO J 1999; 18: 595-604.
-
(1999)
EMBO J
, vol.18
, pp. 595-604
-
-
Munck Petersen, C.1
Nielsen, M.S.2
Jacobsen, C.3
Tauris, J.4
Jacobsen, L.5
Gliemann, J.6
-
34
-
-
10744219632
-
Sortilin is essential for proNGF-induced neuronal cell death
-
Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, et al. Sortilin is essential for proNGF-induced neuronal cell death. Nature 2004; 427: 843-848
-
(2004)
Nature
, vol.427
, pp. 843-848
-
-
Nykjaer, A.1
Lee, R.2
Teng, K.K.3
Jansen, P.4
Madsen, P.5
Nielsen, M.S.6
-
35
-
-
20044370999
-
ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin
-
Teng HK, Teng KK, Lee R, Wright S, Tevar S, Almeida RD, et al. ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci 2005; 25: 5455-5463
-
(2005)
J Neurosci
, vol.25
, pp. 5455-5463
-
-
Teng, H.K.1
Teng, K.K.2
Lee, R.3
Wright, S.4
Tevar, S.5
Almeida, R.D.6
-
36
-
-
0033974624
-
Expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 in the somatosensory cortex of the mature rat: Coexpression with high-affinity neurotrophin receptors
-
Pitts AF, Miller MW. Expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 in the somatosensory cortex of the mature rat: coexpression with high-affinity neurotrophin receptors. J Comp Neurol 2000; 418: 241-254
-
(2000)
J Comp Neurol
, vol.418
, pp. 241-254
-
-
Pitts, A.F.1
Miller, M.W.2
-
37
-
-
36849045117
-
Cholinesterase in human brain: The effect of cholinesterase inhibitors on Alzheimer's disease and related disorder's
-
Giacobini E, Pepeu G, Ed. Informa Healthcare
-
Giacobini E. Cholinesterase in human brain: the effect of cholinesterase inhibitors on Alzheimer's disease and related disorder's. In: Giacobini E, Pepeu G, Ed. The Brain Cholinergic System in Health and Disease. Informa Healthcare 2006; pp. 235-264
-
(2006)
The Brain Cholinergic System in Health and Disease
, pp. 235-264
-
-
Giacobini, E.1
-
38
-
-
0037121659
-
Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75
-
Culmsee C, Gerling N, Lehmann M, Nikolova-Karakashian M, Prehn JH, Mattson MP, et al. Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75. Neuroscience 2002; 115: 1089-1108
-
(2002)
Neuroscience
, vol.115
, pp. 1089-1108
-
-
Culmsee, C.1
Gerling, N.2
Lehmann, M.3
Nikolova-Karakashian, M.4
Prehn, J.H.5
Mattson, M.P.6
-
39
-
-
0034941330
-
Nerve growth factor signaling, neuroprotection, and neural repair
-
Sofroniew MV, Howe CL, Mobley WC. Nerve growth factor signaling, neuroprotection, and neural repair. Annu Rev Neurosci 2001; 24: 1217-1281
-
(2001)
Annu Rev Neurosci
, vol.24
, pp. 1217-1281
-
-
Sofroniew, M.V.1
Howe, C.L.2
Mobley, W.C.3
-
40
-
-
0023643241
-
Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor
-
Fischer W, Wictorin K, Bjorklund A, Williams LR, Varon S, Gage FH. Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature 1987; 329: 65-68
-
(1987)
Nature
, vol.329
, pp. 65-68
-
-
Fischer, W.1
Wictorin, K.2
Bjorklund, A.3
Williams, L.R.4
Varon, S.5
Gage, F.H.6
-
41
-
-
0028307718
-
Nerve growth factor reverses spatial memory impairments in aged rats
-
Fischer W. Nerve growth factor reverses spatial memory impairments in aged rats. Neurochem Int 1994; 25: 47-52.
-
(1994)
Neurochem Int
, vol.25
, pp. 47-52
-
-
Fischer, W.1
-
42
-
-
0002318588
-
Nerve growth factor increases choline acetyltransferase activity in developing basal forebrain neurons
-
Mobley WC, Rutkowski JL, Tennekoon GI, Gemski J, Buchanan K, Johnston MV. Nerve growth factor increases choline acetyltransferase activity in developing basal forebrain neurons. Brain Res 1986; 387: 53-62.
-
(1986)
Brain Res
, vol.387
, pp. 53-62
-
-
Mobley, W.C.1
Rutkowski, J.L.2
Tennekoon, G.I.3
Gemski, J.4
Buchanan, K.5
Johnston, M.V.6
-
43
-
-
0031738197
-
The time course of nerve growth factor content in different neuropsychiatric diseases - A unifying hypothesis
-
Hellweg R, von Richthofen S, Anders D, Baethge C, Röpke S, Hartung HD, et al. The time course of nerve growth factor content in different neuropsychiatric diseases - a unifying hypothesis. J Neural Transm 1998; 105: 871-903.
-
(1998)
J Neural Transm
, vol.105
, pp. 871-903
-
-
Hellweg, R.1
Von Richthofen, S.2
Anders, D.3
Baethge, C.4
Röpke, S.5
Hartung, H.D.6
-
45
-
-
0023186290
-
Nerve growth factor selectively increases cholinergic markers but not neuropeptides in rat basal forebrain culture
-
Martinez HJ, Dreyfus CF, Jonkait GM, Black IB. Nerve growth factor selectively increases cholinergic markers but not neuropeptides in rat basal forebrain culture. Brain Res 1987; 412: 295-301.
-
(1987)
Brain Res
, vol.412
, pp. 295-301
-
-
Martinez, H.J.1
Dreyfus, C.F.2
Jonkait, G.M.3
Black, I.B.4
-
46
-
-
0342941127
-
Chronic intraventricular infusion with NGF improves LTP in old cognitively-impaired rats
-
Bergado JA, Fernández CI, Gómez-Soria A, González O. Chronic intraventricular infusion with NGF improves LTP in old cognitively-impaired rats. Brain Res 1997; 770: 1-9.
-
(1997)
Brain Res
, vol.770
, pp. 1-9
-
-
Bergado, J.A.1
Fernández, C.I.2
Gómez-Soria, A.3
González, O.4
-
47
-
-
0026008812
-
Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain
-
Tuszynski MH, Sang H, Yoshida K, Gage FH. Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain. Ann Neurol 1991; 30: 625-636
-
(1991)
Ann Neurol
, vol.30
, pp. 625-636
-
-
Tuszynski, M.H.1
Sang, H.2
Yoshida, K.3
Gage, F.H.4
-
48
-
-
0030767243
-
The cholinergic system in Alzheimer's disease
-
Kasa P, Rakonczay Z, Gulya K. The cholinergic system in Alzheimer's disease. Prog Neurobiol 1997; 52: 511-535
-
(1997)
Prog Neurobiol
, vol.52
, pp. 511-535
-
-
Kasa, P.1
Rakonczay, Z.2
Gulya, K.3
-
49
-
-
0032103915
-
Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function
-
Gibbs RB. Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function. Exp Neurol 1998; 151: 289-302.
-
(1998)
Exp Neurol
, vol.151
, pp. 289-302
-
-
Gibbs, R.B.1
-
50
-
-
0028297308
-
Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons
-
Crowley C, Spencer SD, Nishimura MC, Chen KS, Pitts-Meek S, Armanini MP, et al. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 1994; 76: 1001-1011
-
(1994)
Cell
, vol.76
, pp. 1001-1011
-
-
Crowley, C.1
Spencer, S.D.2
Nishimura, M.C.3
Chen, K.S.4
Pitts-Meek, S.5
Armanini, M.P.6
-
51
-
-
0037016848
-
Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease
-
Mufson EJ, Ma SY, Dills J, Cochran EJ, Leurgans S, Wuu J, et al. Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease. J Comp Neurol 2002; 443: 136-153
-
(2002)
J Comp Neurol
, vol.443
, pp. 136-153
-
-
Mufson, E.J.1
Ma, S.Y.2
Dills, J.3
Cochran, E.J.4
Leurgans, S.5
Wuu, J.6
-
52
-
-
4644268336
-
Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease
-
Counts SE, Nadeem M, Wuu J, Ginsberg SD, Saragovi HU, Mufson EJ. Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease. Ann Neurol 2004; 56: 520-531
-
(2004)
Ann Neurol
, vol.56
, pp. 520-531
-
-
Counts, S.E.1
Nadeem, M.2
Wuu, J.3
Ginsberg, S.D.4
Saragovi, H.U.5
Mufson, E.J.6
-
53
-
-
0037125974
-
Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in antinerve growth factor mice
-
Capsoni S, Giannotta S, Cattaneo A. Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in antinerve growth factor mice. Proc Natl Acad Sci USA 2002; 99: 12432-12437
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12432-12437
-
-
Capsoni, S.1
Giannotta, S.2
Cattaneo, A.3
-
54
-
-
34548699096
-
NGF-cholinergic dependency in brain aging, MCI and Alzheimer's disease
-
Cuello AC, Bruno MA, Bell KF. NGF-cholinergic dependency in brain aging, MCI and Alzheimer's disease. Curr Alzheimer Res 2007; 4: 351-358
-
(2007)
Curr Alzheimer Res
, vol.4
, pp. 351-358
-
-
Cuello, A.C.1
Bruno, M.A.2
Bell, K.F.3
-
56
-
-
0033813571
-
Neurotrophic factors in Alzheimer's and Parkinson's disease brain
-
Siegel GJ, Chauhan NB. Neurotrophic factors in Alzheimer's and Parkinson's disease brain. Brain Res Brain Res Rev 2000; 33: 199-227.
-
(2000)
Brain Res Brain Res Rev
, vol.33
, pp. 199-227
-
-
Siegel, G.J.1
Chauhan, N.B.2
-
57
-
-
0034087784
-
Region-specific neurotrophin imbalances in Alzheimer disease: Decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas
-
Hock C, Heese K, Hulette C, Rosenberg C, Otten U. Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch Neurol 2000; 57: 846-851
-
(2000)
Arch Neurol
, vol.57
, pp. 846-851
-
-
Hock, C.1
Heese, K.2
Hulette, C.3
Rosenberg, C.4
Otten, U.5
-
58
-
-
0029022112
-
Nerve growth factor in Alzheimer's disease: Increased levels throughout the brain coupled with declines in nucleus basalis
-
Scott SA, Mufson EJ, Weingartner JA, Skau KA, Crutcher KA. Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis. J Neurosci 1995; 15: 6213-6221
-
(1995)
J Neurosci
, vol.15
, pp. 6213-6221
-
-
Scott, S.A.1
Mufson, E.J.2
Weingartner, J.A.3
Skau, K.A.4
Crutcher, K.A.5
-
59
-
-
0037303935
-
Traffic at the intersection of neurotrophic factor signaling and neurodegeneration
-
Salehi A, Delcroix JD, Mobley WC. Traffic at the intersection of neurotrophic factor signaling and neurodegeneration. Trends Neurosci 2003; 26: 73-80.
-
(2003)
Trends Neurosci
, vol.26
, pp. 73-80
-
-
Salehi, A.1
Delcroix, J.D.2
Mobley, W.C.3
-
60
-
-
0347479327
-
Nerve growth factor: From animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease
-
Tuszynski MH, Blesch A. Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease. Prog Brain Res 2004; 146: 441-449
-
(2004)
Prog Brain Res
, vol.146
, pp. 441-449
-
-
Tuszynski, M.H.1
Blesch, A.2
-
61
-
-
0036602976
-
Jekyll-Hyde neurotrophins: The story of proNGF
-
Ibanez CF. Jekyll-Hyde neurotrophins: the story of proNGF. Trends Neurosci 2002; 25: 284-286
-
(2002)
Trends Neurosci
, vol.25
, pp. 284-286
-
-
Ibanez, C.F.1
-
62
-
-
2042465006
-
The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor
-
Fahnestock M, Yu G, Michalski B, Mathew S, Colquhoun A, Ross GM, et al. The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor. J Neurochem 2004; 89: 581-592
-
(2004)
J Neurochem
, vol.89
, pp. 581-592
-
-
Fahnestock, M.1
Yu, G.2
Michalski, B.3
Mathew, S.4
Colquhoun, A.5
Ross, G.M.6
-
63
-
-
36549060136
-
ProNGF, sortilin, and age-related neurodegeneration
-
Al-Shawi R, Hafner A, Chun S, Raza S, Crutcher K, Thrasivoulou C, et al. ProNGF, sortilin, and age-related neurodegeneration. Ann NY Acad Sci 2007; 1119: 208-215
-
(2007)
Ann NY Acad Sci
, vol.1119
, pp. 208-215
-
-
Al-Shawi, R.1
Hafner, A.2
Chun, S.3
Raza, S.4
Crutcher, K.5
Thrasivoulou, C.6
-
65
-
-
0031706422
-
Tissue nerve growth factor concentrations in neuromuscular diseases
-
Stuerenburg HJ, Kunze K. Tissue nerve growth factor concentrations in neuromuscular diseases. Eur J Neurol 1998; 5: 487-490
-
(1998)
Eur J Neurol
, vol.5
, pp. 487-490
-
-
Stuerenburg, H.J.1
Kunze, K.2
-
66
-
-
0036434641
-
Elevated levels of neurotrophins in human biceps brachii tissue of amyotrophic lateral sclerosis
-
Kust BM, Copray JC, Brouwer N, Troost D, Boddeke HW. Elevated levels of neurotrophins in human biceps brachii tissue of amyotrophic lateral sclerosis. Exp Neurol 2002; 177: 419-427
-
(2002)
Exp Neurol
, vol.177
, pp. 419-427
-
-
Kust, B.M.1
Copray, J.C.2
Brouwer, N.3
Troost, D.4
Boddeke, H.W.5
-
67
-
-
0035211890
-
The role of cytokines and growth factors in seizures and their sequelae
-
Jankowsky JL, Patterson PH. The role of cytokines and growth factors in seizures and their sequelae. Prog Neurobiol 2001; 63: 125-149
-
(2001)
Prog Neurobiol
, vol.63
, pp. 125-149
-
-
Jankowsky, J.L.1
Patterson, P.H.2
-
68
-
-
21044458854
-
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
-
Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, et al. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med 2005; 11: 551-555
-
(2005)
Nat Med
, vol.11
, pp. 551-555
-
-
Tuszynski, M.H.1
Thal, L.2
Pay, M.3
Salmon, D.P.4
U, H.S.5
Bakay, R.6
-
69
-
-
0005868926
-
Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease
-
Eriksdotter Jonhagen M, Nordberg A, Amberla K, Backman L, Ebendal T, Meyerson B, et al. Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease. Dement Geriatr Cogn Disord 1998; 9: 246-257
-
(1998)
Dement Geriatr Cogn Disord
, vol.9
, pp. 246-257
-
-
Eriksdotter Jonhagen, M.1
Nordberg, A.2
Amberla, K.3
Backman, L.4
Ebendal, T.5
Meyerson, B.6
-
70
-
-
0030002982
-
Gene therapy in the adult primate brain: Intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration
-
Tuszynski MH, Roberts J, Senut MC, U HS, Gage FH. Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration. Gene Ther 1996; 3: 305-314
-
(1996)
Gene Ther
, vol.3
, pp. 305-314
-
-
Tuszynski, M.H.1
Roberts, J.2
Senut, M.C.3
U, H.S.4
Gage, F.H.5
-
71
-
-
34249941829
-
Nerve growth factor gene therapy in Alzheimer disease
-
Tuszynski MH. Nerve growth factor gene therapy in Alzheimer disease. Alzheimer Dis Assoc Disord 2007; 21: 179-189
-
(2007)
Alzheimer Dis Assoc Disord
, vol.21
, pp. 179-189
-
-
Tuszynski, M.H.1
-
72
-
-
13444301249
-
Neurotrophin-based strategies for neuroprotection
-
Longo FM, Massa SM. Neurotrophin-based strategies for neuroprotection. J Alzheimers Dis 2004; 6: S13-S7.
-
(2004)
J Alzheimers Dis
, vol.6
-
-
Longo, F.M.1
Massa, S.M.2
-
73
-
-
0642370866
-
Alzheimer's therapeutics: Neurotrophin domain small molecule mimetics
-
Massa SM, Xie Y, Longo FM. Alzheimer's therapeutics: neurotrophin domain small molecule mimetics. J Mol Neurosci 2003; 20: 323-326
-
(2003)
J Mol Neurosci
, vol.20
, pp. 323-326
-
-
Massa, S.M.1
Xie, Y.2
Longo, F.M.3
-
74
-
-
0034703031
-
Nerve growth factor (NGF) loop 4 dimeric mimetics activate ERK and AKT and promote NGF-like neurotrophic effects
-
Xie Y, Tisi MA, Yeo TT, Longo FM. Nerve growth factor (NGF) loop 4 dimeric mimetics activate ERK and AKT and promote NGF-like neurotrophic effects. J Biol Chem 2000; 275: 29868-29874
-
(2000)
J Biol Chem
, vol.275
, pp. 29868-29874
-
-
Xie, Y.1
Tisi, M.A.2
Yeo, T.T.3
Longo, F.M.4
-
75
-
-
40849083920
-
A new nerve growth factor-mimetic peptide active on neuropathic pain in rats
-
Colangelo AM, Bianco MR, Vitagliano L, Cavaliere C, Cirillo G, De Gioia L, et al. A new nerve growth factor-mimetic peptide active on neuropathic pain in rats. J Neurosci 2008; 28: 2698-2709
-
(2008)
J Neurosci
, vol.28
, pp. 2698-2709
-
-
Colangelo, A.M.1
Bianco, M.R.2
Vitagliano, L.3
Cavaliere, C.4
Cirillo, G.5
De Gioia, L.6
-
76
-
-
2342505738
-
Behavioral and histological effects of endoneurial administration of nerve growth factor: Possible implications in neuropathic pain
-
Ruiz G, Ceballos D, Banos JE. Behavioral and histological effects of endoneurial administration of nerve growth factor: possible implications in neuropathic pain. Brain Res 2004; 1011: 1-6.
-
(2004)
Brain Res
, vol.1011
, pp. 1-6
-
-
Ruiz, G.1
Ceballos, D.2
Banos, J.E.3
-
77
-
-
0038631907
-
A multicenter, randomized, placebo controlled, multipledose, safety and pharmacokinetic study of AIT-082 (Neotrofin) in mild Alzheimer's disease patients
-
Grundman M, Capparelli E, Kim HT, Morris JC, Farlow M, Rubin EH, et al. A multicenter, randomized, placebo controlled, multipledose, safety and pharmacokinetic study of AIT-082 (Neotrofin) in mild Alzheimer's disease patients. Life Sci 2003; 73: 539-553
-
(2003)
Life Sci
, vol.73
, pp. 539-553
-
-
Grundman, M.1
Capparelli, E.2
Kim, H.T.3
Morris, J.C.4
Farlow, M.5
Rubin, E.H.6
-
78
-
-
23144453122
-
Clinical application of adenosine and ATP for pain control
-
Hayashida M, Fukuda K, Fukunaga A. Clinical application of adenosine and ATP for pain control. J Anesth 2005; 19: 225-235
-
(2005)
J Anesth
, vol.19
, pp. 225-235
-
-
Hayashida, M.1
Fukuda, K.2
Fukunaga, A.3
-
79
-
-
0035853065
-
Activation of Trk neurotrophin receptors in the absence of neurotrophins
-
Lee FS, Chao MV. Activation of Trk neurotrophin receptors in the absence of neurotrophins. Proc Natl Acad Sci USA 2001; 98: 3555-3560
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3555-3560
-
-
Lee, F.S.1
Chao, M.V.2
-
80
-
-
14844363562
-
Effects of N-PEP-12 on memory among older adults
-
Crook TH, Ferris SH, Alvarez XA, Laredo M, Moessler H. Effects of N-PEP-12 on memory among older adults. Int Clin Psychopharmacol 2005; 20: 97-100.
-
(2005)
Int Clin Psychopharmacol
, vol.20
, pp. 97-100
-
-
Crook, T.H.1
Ferris, S.H.2
Alvarez, X.A.3
Laredo, M.4
Moessler, H.5
-
81
-
-
0034874172
-
Analysis of brain biocompatibility of drug-releasing biodegradable microspheres by scanning and transmission electron microscopy
-
Veziers J, Lesourd M, Jollivet C, Montero-Menei C, Benoit JP, Menei P. Analysis of brain biocompatibility of drug-releasing biodegradable microspheres by scanning and transmission electron microscopy. J Neurosurg 2001; 95: 489-494
-
(2001)
J Neurosurg
, vol.95
, pp. 489-494
-
-
Veziers, J.1
Lesourd, M.2
Jollivet, C.3
Montero-Menei, C.4
Benoit, J.P.5
Menei, P.6
-
82
-
-
33744517635
-
Effects of huperzine a on memory deficits and neurotrophic factors production after transient cerebral ischemia and reperfusion in mice
-
Wang ZF, Tang LL, Yan H, Wang YJ, Tang XC. Effects of huperzine A on memory deficits and neurotrophic factors production after transient cerebral ischemia and reperfusion in mice. Pharmacol Biochem Behav 2006; 83: 603-611
-
(2006)
Pharmacol Biochem Behav
, vol.83
, pp. 603-611
-
-
Wang, Z.F.1
Tang, L.L.2
Yan, H.3
Wang, Y.J.4
Tang, X.C.5
-
83
-
-
0242521526
-
Xaliproden: SR 57746, SR 57746A, xaliproden hydrochloride, xaliprodene
-
Xaliproden: SR 57746, SR 57746A, xaliproden hydrochloride, xaliprodene. Drugs R D 2003; 4: 386-388
-
(2003)
Drugs R D
, vol.4
, pp. 386-388
-
-
-
84
-
-
0030574241
-
Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage
-
Semkova I, Wolz P, Schilling M, Krieglstein J. Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage. Eur J Pharmacol 1996; 315: 19-30.
-
(1996)
Eur J Pharmacol
, vol.315
, pp. 19-30
-
-
Semkova, I.1
Wolz, P.2
Schilling, M.3
Krieglstein, J.4
-
85
-
-
17844406615
-
Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives
-
Mandel S, Weinreb O, Amit T, Youdim MB. Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives. Brain Res Brain Res Rev 2005; 48: 379-387
-
(2005)
Brain Res Brain Res Rev
, vol.48
, pp. 379-387
-
-
Mandel, S.1
Weinreb, O.2
Amit, T.3
Youdim, M.B.4
-
86
-
-
0033984344
-
GABA(B) receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats
-
Heese K, Otten U, Mathivet P, Raiteri M, Marescaux C, Bernasconi R. GABA(B) receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats. Neuropharmacology 2000; 39: 449-462
-
(2000)
Neuropharmacology
, vol.39
, pp. 449-462
-
-
Heese, K.1
Otten, U.2
Mathivet, P.3
Raiteri, M.4
Marescaux, C.5
Bernasconi, R.6
-
87
-
-
17444373978
-
Production of NGF, BDNF and GDNF in mouse astrocyte cultures is strongly enhanced by a cerebral vasodilator, ifenprodil
-
Toyomotoa M, Inouea S, Ohtab K, Kunoc S, Ohtad M, Hayashia K, et al. Production of NGF, BDNF and GDNF in mouse astrocyte cultures is strongly enhanced by a cerebral vasodilator, ifenprodil. Neurosci Lett 2005; 379; 185-189
-
(2005)
Neurosci Lett
, vol.379
, pp. 185-189
-
-
Toyomotoa, M.1
Inouea, S.2
Ohtab, K.3
Kunoc, S.4
Ohtad, M.5
Hayashia, K.6
-
88
-
-
33748916428
-
Functional roles of the NTS2 and NTS3 receptors
-
Mazella J, Vincent JP. Functional roles of the NTS2 and NTS3 receptors. Peptides 2006; 27: 2469-2475
-
(2006)
Peptides
, vol.27
, pp. 2469-2475
-
-
Mazella, J.1
Vincent, J.P.2
-
89
-
-
0026058675
-
Primary structure and biological activity of human brain-derived neurotrophic factor
-
Rosenthal A, Goeddel DV, Nguyen T, Martin E, Burton LE, Shih A, et al. Primary structure and biological activity of human brain-derived neurotrophic factor. Endocrinology 1991; 129: 1289-1294
-
(1991)
Endocrinology
, vol.129
, pp. 1289-1294
-
-
Rosenthal, A.1
Goeddel, D.V.2
Nguyen, T.3
Martin, E.4
Burton, L.E.5
Shih, A.6
-
90
-
-
0025279814
-
Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
-
Hofer M, Pagliusi SR, Hohn A, Leibrock J, Barde Y-A. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J 1990; 9: 2459-2464
-
(1990)
EMBO J
, vol.9
, pp. 2459-2464
-
-
Hofer, M.1
Pagliusi, S.R.2
Hohn, A.3
Leibrock, J.4
Barde, Y.-A.5
-
91
-
-
0032904490
-
Distribution and retrograde transport of trophic factors in the central nervous system: Functional implications for the treatment of neurodegenerative diseases
-
Mufson EJ, Kroin JS, Sendera TJ, Sobreviela T. Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases. Prog Neurobiol 1999; 57: 451-484
-
(1999)
Prog Neurobiol
, vol.57
, pp. 451-484
-
-
Mufson, E.J.1
Kroin, J.S.2
Sendera, T.J.3
Sobreviela, T.4
-
92
-
-
0026787533
-
Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
-
Schecterson LC, Bothwell M. Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons. Neuron 1992; 9: 449-463
-
(1992)
Neuron
, vol.9
, pp. 449-463
-
-
Schecterson, L.C.1
Bothwell, M.2
-
93
-
-
0030955975
-
Distribution of brain-derived neurotrophic factor in rats and its changes with development in the brain
-
Katoh-Semba R, Takeguchi IK, Semba R, Kato K. Distribution of brain-derived neurotrophic factor in rats and its changes with development in the brain. J Neurochem 1997; 69: 34-42.
-
(1997)
J Neurochem
, vol.69
, pp. 34-42
-
-
Katoh-Semba, R.1
Takeguchi, I.K.2
Semba, R.3
Kato, K.4
-
94
-
-
0036734833
-
Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
-
Lee J, Duan W, Mattson MP. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem 2002; 82: 1367-1375
-
(2002)
J Neurochem
, vol.82
, pp. 1367-1375
-
-
Lee, J.1
Duan, W.2
Mattson, M.P.3
-
95
-
-
0032582853
-
Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus
-
Oliff HS, Berchtold NC, Isackson P, Cotman CW. Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus. Mol Brain Res 1998; 61: 147-153
-
(1998)
Mol Brain Res
, vol.61
, pp. 147-153
-
-
Oliff, H.S.1
Berchtold, N.C.2
Isackson, P.3
Cotman, C.W.4
-
96
-
-
0032957382
-
Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
-
Young D, Lawlor PA, Leone P, Dragunow M, During MJ. Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nat Med 1999; 5: 448-453
-
(1999)
Nat Med
, vol.5
, pp. 448-453
-
-
Young, D.1
Lawlor, P.A.2
Leone, P.3
Dragunow, M.4
During, M.J.5
-
97
-
-
5644251587
-
Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity
-
Pang PT, Teng HK, Zaitsev E, Woo NT, Sakata K, Zhen S, et al. Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 2004; 306: 487-491
-
(2004)
Science
, vol.306
, pp. 487-491
-
-
Pang, P.T.1
Teng, H.K.2
Zaitsev, E.3
Woo, N.T.4
Sakata, K.5
Zhen, S.6
-
98
-
-
33846101430
-
Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus
-
Bekinschtein P, Cammarota M, Igaz LM, Bevilaqua LR, Izquierdo I, Medina JH. Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus. Neuron 2007; 53: 261-277
-
(2007)
Neuron
, vol.53
, pp. 261-277
-
-
Bekinschtein, P.1
Cammarota, M.2
Igaz, L.M.3
Bevilaqua, L.R.4
Izquierdo, I.5
Medina, J.H.6
-
99
-
-
4644351697
-
BDNF-induced LTP in dentate gyrus is impaired with age: Analysis of changes in cell signaling events
-
Gooney M, Messaoudi E, Maher FO, Bramham CR, Lynch MA. BDNF-induced LTP in dentate gyrus is impaired with age: analysis of changes in cell signaling events. Neurobiol Aging 2004; 25: 1323-1331
-
(2004)
Neurobiol Aging
, vol.25
, pp. 1323-1331
-
-
Gooney, M.1
Messaoudi, E.2
Maher, F.O.3
Bramham, C.R.4
Lynch, M.A.5
-
100
-
-
0032561737
-
Expression of BDNF and trkB as a function of age and cognitive performance
-
Croll SD, Ip NY, Lindsay RM, Wiegand SJ. Expression of BDNF and trkB as a function of age and cognitive performance. Brain Res 1998; 812: 200-208
-
(1998)
Brain Res
, vol.812
, pp. 200-208
-
-
Croll, S.D.1
Ip, N.Y.2
Lindsay, R.M.3
Wiegand, S.J.4
-
101
-
-
0030475453
-
The effects of intrahippocampal BDNF and NGF on spatial learning in aged Long Evans rats
-
Pelleymounter MA, Cullen MJ, Baker MB, Gollub M, Wellman C. The effects of intrahippocampal BDNF and NGF on spatial learning in aged Long Evans rats. Mol Chem Neuropathol 1996; 29: 211-226
-
(1996)
Mol Chem Neuropathol
, vol.29
, pp. 211-226
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Gollub, M.4
Wellman, C.5
-
102
-
-
17144469657
-
Neurotrophic factors: Basis for their clinical application
-
Morís G, Vega JA. Neurotrophic factors: basis for their clinical application. Neurologia 2003; 18: 18-28.
-
(2003)
Neurologia
, vol.18
, pp. 18-28
-
-
Morís, G.1
Vega, J.A.2
-
103
-
-
0029436825
-
Neurotrophic factors and amyotrophic lateral sclerosis
-
Askanas V. Neurotrophic factors and amyotrophic lateral sclerosis. Adv Neurol 1995; 68: 241-244
-
(1995)
Adv Neurol
, vol.68
, pp. 241-244
-
-
Askanas, V.1
-
104
-
-
0035863081
-
Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor are required simultaneously for survival of dopaminergic primary sensory neurons in vivo
-
Erickson JT, Brosenitsch TA, Katz DM. Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor are required simultaneously for survival of dopaminergic primary sensory neurons in vivo. J Neurosci 2001; 21: 581-589
-
(2001)
J Neurosci
, vol.21
, pp. 581-589
-
-
Erickson, J.T.1
Brosenitsch, T.A.2
Katz, D.M.3
-
106
-
-
0028266334
-
Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus
-
Knipper M, da Penha Berzaghi M, Blöchl A, Breer H, Thoenen H, Lindholm D. Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci 1994; 6: 668-671
-
(1994)
Eur J Neurosci
, vol.6
, pp. 668-671
-
-
Knipper, M.1
Da Penha Berzaghi, M.2
Blöchl, A.3
Breer, H.4
Thoenen, H.5
Lindholm, D.6
-
107
-
-
0035076610
-
Neurotrophins differentially enhance acetylcholine release, acetylcholine content and choline acetyltransferase activity in basal forebrain neurons
-
Auld DS, Mennicken F, Day JC, Quirion R. Neurotrophins differentially enhance acetylcholine release, acetylcholine content and choline acetyltransferase activity in basal forebrain neurons. J Neurochem 2001; 77: 253-262
-
(2001)
J Neurochem
, vol.77
, pp. 253-262
-
-
Auld, D.S.1
Mennicken, F.2
Day, J.C.3
Quirion, R.4
-
108
-
-
0033517723
-
Profound and selective loss of catalytic TrkB immunoreactivity in Alzheimer's disease
-
Allen SJ, Wilcock GK, Dawbarn D. Profound and selective loss of catalytic TrkB immunoreactivity in Alzheimer's disease. Biochem Biophys Res Commun 1999; 264: 648-651
-
(1999)
Biochem Biophys Res Commun
, vol.264
, pp. 648-651
-
-
Allen, S.J.1
Wilcock, G.K.2
Dawbarn, D.3
-
109
-
-
0032890036
-
An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease
-
Murer MG, Boissiere F, Yan Q, Hunot S, Villares J, Faucheux B, et al. An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease. Neuroscience 1999; 88: 1015-1032
-
(1999)
Neuroscience
, vol.88
, pp. 1015-1032
-
-
Murer, M.G.1
Boissiere, F.2
Yan, Q.3
Hunot, S.4
Villares, J.5
Faucheux, B.6
-
110
-
-
0033762265
-
Reduced BDNF mRNA expression in the Parkinson's disease substantia nigra
-
Howells DW, Porritt MJ, Wong JY, Batchelor PE, Kalnins R, Hughes AJ, et al. Reduced BDNF mRNA expression in the Parkinson's disease substantia nigra. Exp Neurol 2000; 166: 127-135
-
(2000)
Exp Neurol
, vol.166
, pp. 127-135
-
-
Howells, D.W.1
Porritt, M.J.2
Wong, J.Y.3
Batchelor, P.E.4
Kalnins, R.5
Hughes, A.J.6
-
111
-
-
26444562924
-
Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra
-
von Bohlen und Halbach O, Minichiello L, Unsicker K. Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra. FASEB J 2005; 19: 1740-1742
-
(2005)
FASEB J
, vol.19
, pp. 1740-1742
-
-
Von Bohlen1
Halbach, O.2
Minichiello, L.3
Unsicker, K.4
-
112
-
-
0034040626
-
Decreased phosphorylation levels of TrkB neurotrophin receptor in the spinal cords from patients with amyotrophic lateral sclerosis
-
Mutoh T, Sobue G, Hamano T, Kuriyama M, Hirayama M, Yamamoto M, et al. Decreased phosphorylation levels of TrkB neurotrophin receptor in the spinal cords from patients with amyotrophic lateral sclerosis. Neurochem Res 2000; 25: 239-245
-
(2000)
Neurochem Res
, vol.25
, pp. 239-245
-
-
Mutoh, T.1
Sobue, G.2
Hamano, T.3
Kuriyama, M.4
Hirayama, M.5
Yamamoto, M.6
-
113
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, et al. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 2001; 293: 493-498
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
-
114
-
-
0028815653
-
Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
-
Nibuya M, Morinobu S, Duman RS. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 1995; 15: 7539-7547
-
(1995)
J Neurosci
, vol.15
, pp. 7539-7547
-
-
Nibuya, M.1
Morinobu, S.2
Duman, R.S.3
-
115
-
-
0035881828
-
Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
-
Chen B, Dowlatshahi D, MacQueen GM, Wang JF, Young LT. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 2001; 50: 260-265
-
(2001)
Biol Psychiatry
, vol.50
, pp. 260-265
-
-
Chen, B.1
Dowlatshahi, D.2
MacQueen, G.M.3
Wang, J.F.4
Young, L.T.5
-
116
-
-
0041880262
-
Untreated depression and hippocampal volume loss
-
Sheline YI, Gado MH, Kraemer HC. Untreated depression and hippocampal volume loss. Am J Psychiatry 2003; 160: 1516-1518
-
(2003)
Am J Psychiatry
, vol.160
, pp. 1516-1518
-
-
Sheline, Y.I.1
Gado, M.H.2
Kraemer, H.C.3
-
117
-
-
53049106468
-
An animal model of a behavioral intervention for depression
-
Pollak DD, Monje FJ, Zuckerman L, Denny CA, Drew MR, Kandel ER. An animal model of a behavioral intervention for depression. Neuron 2008; 60: 149-161
-
(2008)
Neuron
, vol.60
, pp. 149-161
-
-
Pollak, D.D.1
Monje, F.J.2
Zuckerman, L.3
Denny, C.A.4
Drew, M.R.5
Kandel, E.R.6
-
119
-
-
18744409324
-
Decreased BDNF signalling in transgenic mice reduces epileptogenesis
-
Lähteinen S, Pitkänen A, Saarelainen T, Nissinen J, Koponen E, Castrén E. Decreased BDNF signalling in transgenic mice reduces epileptogenesis. Eur J Neurosci 2002; 15: 721-734
-
(2002)
Eur J Neurosci
, vol.15
, pp. 721-734
-
-
Lähteinen, S.1
Pitkänen, A.2
Saarelainen, T.3
Nissinen, J.4
Koponen, E.5
Castrén, E.6
-
120
-
-
0032765275
-
Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex
-
Croll SD, Suri C, Compton DL, Simmons MV, Yancopoulos GD, Lindsay RM, et al. Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience 1999; 93: 1491-1506
-
(1999)
Neuroscience
, vol.93
, pp. 1491-1506
-
-
Croll, S.D.1
Suri, C.2
Compton, D.L.3
Simmons, M.V.4
Yancopoulos, G.D.5
Lindsay, R.M.6
-
121
-
-
0036221508
-
Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor
-
Scharfman HE, Goodman JH, Sollas AL, Croll SD. Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor. Exp Neurol 2002; 174: 201-214
-
(2002)
Exp Neurol
, vol.174
, pp. 201-214
-
-
Scharfman, H.E.1
Goodman, J.H.2
Sollas, A.L.3
Croll, S.D.4
-
122
-
-
0037334208
-
A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors
-
Malcangio M, Lessmann V. A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. Trends Pharmacol Sci 2003; 24: 11621.
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 11621
-
-
Malcangio, M.1
Lessmann, V.2
-
123
-
-
0035400009
-
Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model
-
Fukuoka T, Kondo E, Dai Y, Hashimoto N, Noguchi K. Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model. J Neurosci 2001; 21: 4891-4900
-
(2001)
J Neurosci
, vol.21
, pp. 4891-4900
-
-
Fukuoka, T.1
Kondo, E.2
Dai, Y.3
Hashimoto, N.4
Noguchi, K.5
-
124
-
-
0036938785
-
Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn
-
Pezet S, Malcangio M, Lever IJ, Perkinton MS, Thompson SW, Williams RJ, et al. Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn. Mol Cell Neurosci 2002; 21: 684-695
-
(2002)
Mol Cell Neurosci
, vol.21
, pp. 684-695
-
-
Pezet, S.1
Malcangio, M.2
Lever, I.J.3
Perkinton, M.S.4
Thompson, S.W.5
Williams, R.J.6
-
125
-
-
0041701529
-
Gene therapy for neurological disease
-
Tuszynski MH. Gene therapy for neurological disease. Expert Opin Biol Ther 2003; 3: 815-828
-
(2003)
Expert Opin Biol Ther
, vol.3
, pp. 815-828
-
-
Tuszynski, M.H.1
-
126
-
-
0034948287
-
The regrowth of axons within tissue defects in the CNS is promoted by implanted hydrogel matrices that contain BDNF and CNTF producing fibroblasts
-
Loh NK, Woerly S, Bunt SM, Wilton SD, Harvey AR. The regrowth of axons within tissue defects in the CNS is promoted by implanted hydrogel matrices that contain BDNF and CNTF producing fibroblasts. Exp Neurol 2001; 170: 72-84.
-
(2001)
Exp Neurol
, vol.170
, pp. 72-84
-
-
Loh, N.K.1
Woerly, S.2
Bunt, S.M.3
Wilton, S.D.4
Harvey, A.R.5
-
127
-
-
0344076149
-
A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)
-
A controlled trial of recombinant methionyl human BDNF in ALS: the BDNF Study Group (Phase III). Neurology 1999; 52: 1427-1433
-
(1999)
Neurology
, vol.52
, pp. 1427-1433
-
-
-
128
-
-
0034208461
-
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis
-
Ochs G, Penn RD, York M, Giess R, Beck M, Tonn J, et al. A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000; 1: 201-206
-
(2000)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.1
, pp. 201-206
-
-
Ochs, G.1
Penn, R.D.2
York, M.3
Giess, R.4
Beck, M.5
Tonn, J.6
-
130
-
-
0037477393
-
Design of potent peptide mimetics of brain-derived neurotrophic factor
-
O'Leary PD, Hughes RA. Design of potent peptide mimetics of brain-derived neurotrophic factor. J Biol Chem 2003; 278: 25738-25744
-
(2003)
J Biol Chem
, vol.278
, pp. 25738-25744
-
-
O'Leary, P.D.1
Hughes, R.A.2
-
131
-
-
57749120457
-
Design of a conformationally defined and proteolytically stable circular mimetic of Brain-derived Neurotrophic Factor
-
Fletcher JM, Morton CJ, Zwar RA, Murray SS, O'Leary PD, Hughes RA. Design of a conformationally defined and proteolytically stable circular mimetic of Brain-derived Neurotrophic Factor. J Biol Chem 2008; 283: 33375-33383
-
(2008)
J Biol Chem
, vol.283
, pp. 33375-33383
-
-
Fletcher, J.M.1
Morton, C.J.2
Zwar, R.A.3
Murray, S.S.4
O'Leary, P.D.5
Hughes, R.A.6
-
133
-
-
0034764208
-
The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain
-
Marvanová M, Lakso M, Pirhonen J, Nawa H, Wong G, Castrén E. The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain. Mol Cell Neurosci 2001; 18: 247-258
-
(2001)
Mol Cell Neurosci
, vol.18
, pp. 247-258
-
-
Marvanová, M.1
Lakso, M.2
Pirhonen, J.3
Nawa, H.4
Wong, G.5
Castrén, E.6
-
134
-
-
0035799569
-
BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization
-
Guillin O, Diaz J, Carroll P, Griffon N, Schwartz JC, Sokoloff P. BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization. Nature 2001; 411: 86-89
-
(2001)
Nature
, vol.411
, pp. 86-89
-
-
Guillin, O.1
Diaz, J.2
Carroll, P.3
Griffon, N.4
Schwartz, J.C.5
Sokoloff, P.6
-
135
-
-
33750858897
-
Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases
-
Ebadi M, Brown-Borg H, Ren J, Sharma S, Shavali S, El ReFaey H, et al. Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases. Curr Drug Targets 2006; 7: 1513-1529
-
(2006)
Curr Drug Targets
, vol.7
, pp. 1513-1529
-
-
Ebadi, M.1
Brown-Borg, H.2
Ren, J.3
Sharma, S.4
Shavali, S.5
El ReFaey, H.6
-
136
-
-
28744439018
-
Dopamine D3 receptor-preferring agonists induce neurotrophic effects on mesencephalic dopamine neurons
-
Du F, Li R, Huang Y, Li X, Le W. Dopamine D3 receptor-preferring agonists induce neurotrophic effects on mesencephalic dopamine neurons. Eur J Neurosci 2005; 22: 2422-2430
-
(2005)
Eur J Neurosci
, vol.22
, pp. 2422-2430
-
-
Du, F.1
Li, R.2
Huang, Y.3
Li, X.4
Le, W.5
-
137
-
-
0036835002
-
Apomorphine induces trophic factors that support fetal rat mesencephalic dopaminergic neurons in cultures
-
Guo H, Tang Z, Yu Y, Xu L, Jin G, Zhou J. Apomorphine induces trophic factors that support fetal rat mesencephalic dopaminergic neurons in cultures. Eur J Neurosci 2002; 16: 1861-1870
-
(2002)
Eur J Neurosci
, vol.16
, pp. 1861-1870
-
-
Guo, H.1
Tang, Z.2
Yu, Y.3
Xu, L.4
Jin, G.5
Zhou, J.6
-
138
-
-
40349084103
-
Transdermal selegiline: New opportunity for managing depression
-
Tobe EH. Transdermal selegiline: new opportunity for managing depression. J Am Osteopath Assoc 2008; 108: 85-86
-
(2008)
J Am Osteopath Assoc
, vol.108
, pp. 85-86
-
-
Tobe, E.H.1
-
139
-
-
4644312295
-
SGS742: The first GABA(B) receptor antagonist in clinical trials
-
Froestl W, Gallagher M, Jenkins H, Madrid A, Melcher T, Teichman S, et al. SGS742: the first GABA(B) receptor antagonist in clinical trials. Biochem Pharmacol 2004; 68: 1479-1487
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1479-1487
-
-
Froestl, W.1
Gallagher, M.2
Jenkins, H.3
Madrid, A.4
Melcher, T.5
Teichman, S.6
-
140
-
-
57749108326
-
Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs
-
Weinreb O, Mandel S, Bar-Am O, Yogev-Falach M, Avramovich-Tirosh Y, Amit T, et al. Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs. Neurotherapeutics 2009; 6: 163-174
-
(2009)
Neurotherapeutics
, vol.6
, pp. 163-174
-
-
Weinreb, O.1
Mandel, S.2
Bar-Am, O.3
Yogev-Falach, M.4
Avramovich-Tirosh, Y.5
Amit, T.6
-
141
-
-
37049015753
-
Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: New insights and implications for therapy
-
Weinreb O, Amit T, Bar-Am O, Youdim MB. Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy. Ann NY Acad Sci 2007; 1122: 155-168
-
(2007)
Ann NY Acad Sci
, vol.1122
, pp. 155-168
-
-
Weinreb, O.1
Amit, T.2
Bar-Am, O.3
Youdim, M.B.4
-
142
-
-
34249098796
-
AMPA receptor potentiators: Application for depression and Parkinson's disease
-
O'Neill MJ, Witkin JM. AMPA receptor potentiators: application for depression and Parkinson's disease. Curr Drug Targets 2007; 8: 603-620
-
(2007)
Curr Drug Targets
, vol.8
, pp. 603-620
-
-
O'Neill, M.J.1
Witkin, J.M.2
-
143
-
-
0035118639
-
Cognitive deficits in depression: Possible implications for functional neuropathology
-
Austin MP, Mitchell P, Goodwin GM. Cognitive deficits in depression: possible implications for functional neuropathology. Br J Psychiatry 2001; 178: 200-206
-
(2001)
Br J Psychiatry
, vol.178
, pp. 200-206
-
-
Austin, M.P.1
Mitchell, P.2
Goodwin, G.M.3
-
144
-
-
0141595912
-
Neuroimmunophilin ligands: The development of novel neuroregenerative/ neuroprotective compounds
-
Gold BG, Villafranca JE. Neuroimmunophilin ligands: the development of novel neuroregenerative/neuroprotective compounds. Curr Top Med Chem 2003; 3: 1368-1375
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 1368-1375
-
-
Gold, B.G.1
Villafranca, J.E.2
-
145
-
-
0037466474
-
Immunosuppressive (FK506) and non-immunosuppressive (GPI1046) immunophilin ligands activate neurotrophic factors in the mouse brain
-
Tanaka K, Fujita N, Ogawa N. Immunosuppressive (FK506) and non-immunosuppressive (GPI1046) immunophilin ligands activate neurotrophic factors in the mouse brain. Brain Res 2003; 970: 250-253
-
(2003)
Brain Res
, vol.970
, pp. 250-253
-
-
Tanaka, K.1
Fujita, N.2
Ogawa, N.3
-
146
-
-
34548699099
-
Tripchlorolide protects against MPTP-induced neurotoxicity in C57BL/6 mice
-
Hong Z, Wang G, Gu J, Pan J, Bai L, Zhang S, et al. Tripchlorolide protects against MPTP-induced neurotoxicity in C57BL/6 mice. Eur J Neurosci 2007; 26: 1500-1508
-
(2007)
Eur J Neurosci
, vol.26
, pp. 1500-1508
-
-
Hong, Z.1
Wang, G.2
Gu, J.3
Pan, J.4
Bai, L.5
Zhang, S.6
-
147
-
-
0029804160
-
Pharmacological characterization of glial cell line-derived neurotrophic factor (GDNF): Implications for GDNF as a therapeutic molecule for treating neurodegenerative diseases
-
Lapchak PA, Jiao S, Miller PJ, Williams LR, Cummins V, Inouye G, et al. Pharmacological characterization of glial cell line-derived neurotrophic factor (GDNF): implications for GDNF as a therapeutic molecule for treating neurodegenerative diseases. Cell Tissue Res 1996; 286: 179-189
-
(1996)
Cell Tissue Res
, vol.286
, pp. 179-189
-
-
Lapchak, P.A.1
Jiao, S.2
Miller, P.J.3
Williams, L.R.4
Cummins, V.5
Inouye, G.6
-
148
-
-
0032939002
-
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle
-
Rosenblad C, Kirik D, Devaux B, Moffat B, Phillips HS, Björklund A. Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle. Eur J Neurosci 1999; 11: 1554-1566
-
(1999)
Eur J Neurosci
, vol.11
, pp. 1554-1566
-
-
Rosenblad, C.1
Kirik, D.2
Devaux, B.3
Moffat, B.4
Phillips, H.S.5
Björklund, A.6
-
149
-
-
0032005510
-
Persephin, a novel neurotrophic factor related to GDNF and neurturin
-
Milbrandt J, de Sauvage FJ, Fahrner TJ, Baloh RH, Leitner ML, Tansey MG, et al. Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron 1998; 20: 245-253
-
(1998)
Neuron
, vol.20
, pp. 245-253
-
-
Milbrandt, J.1
De Sauvage, F.J.2
Fahrner, T.J.3
Baloh, R.H.4
Leitner, M.L.5
Tansey, M.G.6
-
150
-
-
0032408664
-
Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex
-
Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, et al. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron 1998; 21: 1291-1302
-
(1998)
Neuron
, vol.21
, pp. 1291-1302
-
-
Baloh, R.H.1
Tansey, M.G.2
Lampe, P.A.3
Fahrner, T.J.4
Enomoto, H.5
Simburger, K.S.6
-
151
-
-
33747130712
-
Evolution of the GDNF family ligands and receptors
-
Airaksinen MS, Holm L, Hatinen T. Evolution of the GDNF family ligands and receptors. Brain Behav Evol 2006; 68: 181-190
-
(2006)
Brain Behav Evol
, vol.68
, pp. 181-190
-
-
Airaksinen, M.S.1
Holm, L.2
Hatinen, T.3
-
152
-
-
33846501598
-
GDNF family receptor complexes are emerging drug targets
-
Bespalov MM, Saarma M. GDNF family receptor complexes are emerging drug targets. Trends Pharmacol Sci 2007; 28: 68-74.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 68-74
-
-
Bespalov, M.M.1
Saarma, M.2
-
153
-
-
14644433821
-
Anatomical basis of glial cell line-derived neurotrophic factor expression in the striatum and related basal ganglia during postnatal development of the rat
-
Oo TF, Ries V, Cho J, Kholodilov N, Burke RE. Anatomical basis of glial cell line-derived neurotrophic factor expression in the striatum and related basal ganglia during postnatal development of the rat. J Comp Neurol 2005; 484: 57-67.
-
(2005)
J Comp Neurol
, vol.484
, pp. 57-67
-
-
Oo, T.F.1
Ries, V.2
Cho, J.3
Kholodilov, N.4
Burke, R.E.5
-
155
-
-
0032484596
-
GDNF and its receptor component Ret in injured human nerves and dorsal root ganglia
-
Bär KJ, Saldanha GJ, Kennedy AJ, Facer P, Birch R, Carlstedt T, et al. GDNF and its receptor component Ret in injured human nerves and dorsal root ganglia. Neuroreport 1998; 9: 43-47
-
(1998)
Neuroreport
, vol.9
, pp. 43-47
-
-
Bär, K.J.1
Saldanha, G.J.2
Kennedy, A.J.3
Facer, P.4
Birch, R.5
Carlstedt, T.6
-
156
-
-
5644261276
-
Retrograde propagation of GDNF-mediated signals in sympathetic neurons
-
Coulpier M, Ibáñez CF. Retrograde propagation of GDNF-mediated signals in sympathetic neurons. Mol Cell Neurosci 2004; 27: 132-139
-
(2004)
Mol Cell Neurosci
, vol.27
, pp. 132-139
-
-
Coulpier, M.1
Ibáñez, C.F.2
-
157
-
-
0034671913
-
Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase
-
Besset V, Scott RP, Ibáñez CF. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase. J Biol Chem 2000; 275: 39159-39166
-
(2000)
J Biol Chem
, vol.275
, pp. 39159-39166
-
-
Besset, V.1
Scott, R.P.2
Ibáñez, C.F.3
-
158
-
-
0033962594
-
Neuroprotective mechanism of glial cell line-derived neurotrophic factor in mesencephalic neurons
-
Sawada H, Ibi M, Kihara T, Urushitani M, Nakanishi M, Akaike A, et al. Neuroprotective mechanism of glial cell line-derived neurotrophic factor in mesencephalic neurons. J Neurochem 2000; 74: 1175-1184
-
(2000)
J Neurochem
, vol.74
, pp. 1175-1184
-
-
Sawada, H.1
Ibi, M.2
Kihara, T.3
Urushitani, M.4
Nakanishi, M.5
Akaike, A.6
-
159
-
-
34247862375
-
Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra
-
Mijatovic J, Airavaara M, Planken A, Auvinen P, Raasmaja A, Piepponen TP, et al. Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra. J Neurosci 2007; 27: 4799-4809
-
(2007)
J Neurosci
, vol.27
, pp. 4799-4809
-
-
Mijatovic, J.1
Airavaara, M.2
Planken, A.3
Auvinen, P.4
Raasmaja, A.5
Piepponen, T.P.6
-
160
-
-
0038488948
-
The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands
-
Paratcha G, Ledda F, Ibáñez CF. The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands. Cell 2003; 113: 867-879
-
(2003)
Cell
, vol.113
, pp. 867-879
-
-
Paratcha, G.1
Ledda, F.2
Ibáñez, C.F.3
-
161
-
-
0345352666
-
GDNF promotes tubulogenesis of GFR alpha 1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase
-
Popsueva A, Poteryaev D, Arighi E, Meng XJ, Angers-Loustau A, Kaplan D, et al. GDNF promotes tubulogenesis of GFR alpha 1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase. J Cell Biol 2003; 161: 119-129
-
(2003)
J Cell Biol
, vol.161
, pp. 119-129
-
-
Popsueva, A.1
Poteryaev, D.2
Arighi, E.3
Meng, X.J.4
Angers-Loustau, A.5
Kaplan, D.6
-
162
-
-
0033802514
-
GDNF enhances the synaptic efficacy of dopaminergic neurons in culture
-
Bourque MJ, Trudeau LE. GDNF enhances the synaptic efficacy of dopaminergic neurons in culture. Eur J Neurosci 2000; 12; 3172-3180
-
(2000)
Eur J Neurosci
, vol.12
, pp. 3172-3180
-
-
Bourque, M.J.1
Trudeau, L.E.2
-
163
-
-
33847226897
-
GDNF and GFRα1 promote formation of neuronal synapses by ligand-induced cell adhesion
-
Ledda F, Paratcha G, Sandoval-Guzman T, Ibáñez CF. GDNF and GFRα1 promote formation of neuronal synapses by ligand-induced cell adhesion. Nat Neurosci 2007; 10: 293-300.
-
(2007)
Nat Neurosci
, vol.10
, pp. 293-300
-
-
Ledda, F.1
Paratcha, G.2
Sandoval-Guzman, T.3
Ibáñez, C.F.4
-
164
-
-
0037911432
-
Intraputamenal infusion of GDNF in aged rhesus monkeys: Distribution and dopaminergic effects
-
Ai Y, Markesbery W, Zhang Z, Grondin R, Elseberry D, Gerhardt GA, et al. Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects. J Comp Neurol 2003; 461: 250-261
-
(2003)
J Comp Neurol
, vol.461
, pp. 250-261
-
-
Ai, Y.1
Markesbery, W.2
Zhang, Z.3
Grondin, R.4
Elseberry, D.5
Gerhardt, G.A.6
-
165
-
-
0037336930
-
Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys
-
Grondin R, Cass WA, Zhang Z, Stanford JA, Gash DM, Gerhardt GA. Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys. J Neurosci 2003; 23: 1974-1980
-
(2003)
J Neurosci
, vol.23
, pp. 1974-1980
-
-
Grondin, R.1
Cass, W.A.2
Zhang, Z.3
Stanford, J.A.4
Gash, D.M.5
Gerhardt, G.A.6
-
166
-
-
0036787532
-
Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys
-
Grondin R, Zhang Z, Yi A, Cass WA, Maswood N, Andersen AH, et al. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain 2002; 125: 2191-2201
-
(2002)
Brain
, vol.125
, pp. 2191-2201
-
-
Grondin, R.1
Zhang, Z.2
Yi, A.3
Cass, W.A.4
Maswood, N.5
Andersen, A.H.6
-
167
-
-
0345732569
-
The potential of GDNF as a treatment for Parkinson's disease
-
Hurelbrink CB, Barker RA. The potential of GDNF as a treatment for Parkinson's disease. Exp Neurol 2004; 185: 1-6.
-
(2004)
Exp Neurol
, vol.185
, pp. 1-6
-
-
Hurelbrink, C.B.1
Barker, R.A.2
-
168
-
-
0028109717
-
GDNF: A potent survival factor for motoneurons present in peripheral nerve and muscle
-
Henderson CE, Phillips HS, Pollock RA, Davies AM, Lemeulle C, Armanini M, et al. GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science 1994; 266: 1062-1064
-
(1994)
Science
, vol.266
, pp. 1062-1064
-
-
Henderson, C.E.1
Phillips, H.S.2
Pollock, R.A.3
Davies, A.M.4
Lemeulle, C.5
Armanini, M.6
-
169
-
-
0038249170
-
Direct brain infusion of glial cell linederived neurotrophic factor in Parkinson disease
-
Gill SS, Patel NK, Hotton GR, O'Sullivan K, McCarter R, Bunnage M, et al. Direct brain infusion of glial cell linederived neurotrophic factor in Parkinson disease. Nat Med 2003; 9: 589-595
-
(2003)
Nat Med
, vol.9
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Hotton, G.R.3
O'Sullivan, K.4
McCarter, R.5
Bunnage, M.6
-
170
-
-
14844311296
-
Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
-
Slevin JT, Gerhardt GA, Smith CD, Gash DM, Kryscio R, Young B. Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J Neurosurg 2005; 102: 216-222
-
(2005)
J Neurosurg
, vol.102
, pp. 216-222
-
-
Slevin, J.T.1
Gerhardt, G.A.2
Smith, C.D.3
Gash, D.M.4
Kryscio, R.5
Young, B.6
-
171
-
-
58349096894
-
Future of cell and gene therapies for Parkinson's disease
-
Isacson O, Kordower JH. Future of cell and gene therapies for Parkinson's disease. Ann Neurol 2008; 2: S122-38.
-
(2008)
Ann Neurol
, vol.2
-
-
Isacson, O.1
Kordower, J.H.2
-
173
-
-
33645140627
-
Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates
-
Behrstock S, Ebert A, McHugh J, Vosberg S, Moore J, Schneider B, et al. Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates. Gene Ther 2006; 13: 379-388
-
(2006)
Gene Ther
, vol.13
, pp. 379-388
-
-
Behrstock, S.1
Ebert, A.2
McHugh, J.3
Vosberg, S.4
Moore, J.5
Schneider, B.6
-
174
-
-
0037210204
-
XIB4035, a novel nonpeptidyl small molecule agonist for GFRα-1
-
Tokugawa K, Yamamoto K, Nishiguchi M, Sekine T, Sakai M, Ueki T, et al. XIB4035, a novel nonpeptidyl small molecule agonist for GFRα-1. Neurochem Int 2003; 42: 81-86
-
(2003)
Neurochem Int
, vol.42
, pp. 81-86
-
-
Tokugawa, K.1
Yamamoto, K.2
Nishiguchi, M.3
Sekine, T.4
Sakai, M.5
Ueki, T.6
-
175
-
-
46749109164
-
PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease
-
Visanji NP, Orsi A, Johnston TH, Howson PA, Dixon K, Callizot N, et al. PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. FASEB J 2008; 22: 2488-2497
-
(2008)
FASEB J
, vol.22
, pp. 2488-2497
-
-
Visanji, N.P.1
Orsi, A.2
Johnston, T.H.3
Howson, P.A.4
Dixon, K.5
Callizot, N.6
-
176
-
-
55049090172
-
Driving GDNF expression: The green and the red traffic lights
-
Saavedra A, Baltazar G, Duarte EP. Driving GDNF expression: the green and the red traffic lights. Prog Neurobiol 2008; 86: 186-215.
-
(2008)
Prog Neurobiol
, vol.86
, pp. 186-215
-
-
Saavedra, A.1
Baltazar, G.2
Duarte, E.P.3
-
177
-
-
0037617551
-
Effects of dopamine agonists bromocriptine, pergolide, cabergoline, and SKF-38393 on GDNF, NGF, and BDNF synthesis in cultured mouse astrocytes
-
Ohta K, Kuno S, Mizuta I, Fujinami A, Matsui H, Ohta M. Effects of
-
(2003)
Life Sci
, vol.73
, pp. 617-626
-
-
Ohta, K.1
Kuno, S.2
Mizuta, I.3
Fujinami, A.4
Matsui, H.5
Ohta, M.6
-
178
-
-
33747186125
-
Selective injury to dopaminergic neurons up-regulates GDNF in substantia nigra postnatal cell cultures: Role of neuron-glia crosstalk
-
Saavedra A, Baltazar G, Santos P, Carvalho CM, Duarte EP. Selective injury to dopaminergic neurons up-regulates GDNF in substantia nigra postnatal cell cultures: role of neuron-glia crosstalk. Neurobiol Dis 2006; 23: 533-542
-
(2006)
Neurobiol Dis
, vol.23
, pp. 533-542
-
-
Saavedra, A.1
Baltazar, G.2
Santos, P.3
Carvalho, C.M.4
Duarte, E.P.5
-
179
-
-
31344457324
-
Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells
-
Caumont AS, Octave JN, Hermans E. Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells. Neurosci Lett 2006; 394: 196-201.
-
(2006)
Neurosci Lett
, vol.394
, pp. 196-201
-
-
Caumont, A.S.1
Octave, J.N.2
Hermans, E.3
-
180
-
-
0035860435
-
Riluzole stimulates nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis in cultured mouse astrocytes
-
Mizuta I, Ohta M, Ohta K, Nishimura M, Mizuta E, Kuno S. Riluzole stimulates nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis in cultured mouse astrocytes. Neurosci Lett 2001; 310: 117-120
-
(2001)
Neurosci Lett
, vol.310
, pp. 117-120
-
-
Mizuta, I.1
Ohta, M.2
Ohta, K.3
Nishimura, M.4
Mizuta, E.5
Kuno, S.6
-
181
-
-
33947357645
-
Antidepressants increase glial cell line-derived neurotrophic factor production through monoamine independent activation of protein tyrosine kinase and extracellular signal-regulated kinase in glial cells
-
Hisaoka K, Takebayashi M, Tsuchioka M, Maeda N, Nakata Y, Yamawaki S. Antidepressants increase glial cell line-derived neurotrophic factor production through monoamine independent activation of protein tyrosine kinase and extracellular signal-regulated kinase in glial cells. J Pharmacol Exp Ther 2007; 321: 148-157
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 148-157
-
-
Hisaoka, K.1
Takebayashi, M.2
Tsuchioka, M.3
Maeda, N.4
Nakata, Y.5
Yamawaki, S.6
-
182
-
-
0029827559
-
Neurturin, a relative of glial-cell-line-derived neurotrophic factor
-
Kotzbauer PT, Lampe PA, Heuckeroth RO, Golden JP, Creedon DJ, Johnson EM, Jr, et al. Neurturin, a relative of glial-cell-line-derived neurotrophic factor. Nature 1996; 384: 467-470
-
(1996)
Nature
, vol.384
, pp. 467-470
-
-
Kotzbauer, P.T.1
Lampe, P.A.2
Heuckeroth, R.O.3
Golden, J.P.4
Creedon, D.J.5
Johnson Jr., E.M.6
-
183
-
-
0037397517
-
Protective action of recombinant neurturin on dopaminergic neurons in substantia nigra in a rhesus monkey model of Parkinson's disease
-
Li H, He Z, Su T, Ma Y, Lu S, Dai C, et al. Protective action of recombinant neurturin on dopaminergic neurons in substantia nigra in a rhesus monkey model of Parkinson's disease. Neurol Res 2003; 25: 263-267
-
(2003)
Neurol Res
, vol.25
, pp. 263-267
-
-
Li, H.1
He, Z.2
Su, T.3
Ma, Y.4
Lu, S.5
Dai, C.6
-
184
-
-
0037199818
-
Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease
-
Oiwa Y, Yoshimura R, Nakai K, Itakura T. Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease. Brain Res 2002; 947: 271-283
-
(2002)
Brain Res
, vol.947
, pp. 271-283
-
-
Oiwa, Y.1
Yoshimura, R.2
Nakai, K.3
Itakura, T.4
-
185
-
-
33845993229
-
Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP treated monkeys
-
Kordower JH, Herzog CD, Dass B, Bakay RA, Stansell J, 3rd, Gasmi M, et al. Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP treated monkeys. Ann Neurol 2006; 60: 706-715
-
(2006)
Ann Neurol
, vol.60
, pp. 706-715
-
-
Kordower, J.H.1
Herzog, C.D.2
Dass, B.3
Bakay, R.A.4
Stansell III, J.5
Gasmi, M.6
-
186
-
-
34447572589
-
Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys
-
Herzog CD, Dass B, Holden JE, Stansell J, 3rd, Gasmi M, Tuszynski MH, et al. Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys. Mov Disord 2007; 22: 1124-1132
-
(2007)
Mov Disord
, vol.22
, pp. 1124-1132
-
-
Herzog, C.D.1
Dass, B.2
Holden, J.E.3
Stansell III, J.4
Gasmi, M.5
Tuszynski, M.H.6
-
187
-
-
22944465758
-
New approaches for the treatment of pain: The GDNF family of neurotrophic growth factors
-
Sah DW, Ossipov MH, Rossomando A, Silvian L, Porreca F. New approaches for the treatment of pain: the GDNF family of neurotrophic growth factors. Curr Top Med Chem 2005; 5: 577-583
-
(2005)
Curr Top Med Chem
, vol.5
, pp. 577-583
-
-
Sah, D.W.1
Ossipov, M.H.2
Rossomando, A.3
Silvian, L.4
Porreca, F.5
-
188
-
-
0030962825
-
Cytokines which signal through the LIF receptor and their actions in the nervous system
-
Murphy M, Dutton R, Koblar S, Cheema S, Bartlett P. Cytokines which signal through the LIF receptor and their actions in the nervous system. Prog Neurobiol 1997; 52: 355-378
-
(1997)
Prog Neurobiol
, vol.52
, pp. 355-378
-
-
Murphy, M.1
Dutton, R.2
Koblar, S.3
Cheema, S.4
Bartlett, P.5
-
189
-
-
0033168687
-
Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation
-
Nakashima K, Wiese S, Yanagisawa M, Arakawa H, Kimura N, Hisatsune T, et al. Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation. J Neurosci 1999; 19: 5429-5434
-
(1999)
J Neurosci
, vol.19
, pp. 5429-5434
-
-
Nakashima, K.1
Wiese, S.2
Yanagisawa, M.3
Arakawa, H.4
Kimura, N.5
Hisatsune, T.6
-
190
-
-
0031866792
-
Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages
-
Horton AR, Barlett PF, Pennica D, Davies AM. Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages. Eur J Neurosci 1998; 10: 673-679
-
(1998)
Eur J Neurosci
, vol.10
, pp. 673-679
-
-
Horton, A.R.1
Barlett, P.F.2
Pennica, D.3
Davies, A.M.4
-
191
-
-
0021686832
-
Purification of the chick eye ciliary neuronotrophic factor
-
Barbin G, Manthorpe M, Varon S. Purification of the chick eye ciliary neuronotrophic factor. J Neurochem 1984; 43: 1468-1478
-
(1984)
J Neurochem
, vol.43
, pp. 1468-1478
-
-
Barbin, G.1
Manthorpe, M.2
Varon, S.3
-
192
-
-
0027264557
-
Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury
-
Curtis R, Adryan KM, Zhu Y, Harkness PJ, Lindsay RM, Di Stefano PS. Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury. Nature 1993; 365: 253-255
-
(1993)
Nature
, vol.365
, pp. 253-255
-
-
Curtis, R.1
Adryan, K.M.2
Zhu, Y.3
Harkness, P.J.4
Lindsay, R.M.5
Di Stefano, P.S.6
-
193
-
-
0027989754
-
Actions of CNTF and neurotrophins on degenerating motoneurons: Preclinical studies and clinical implications
-
Sendtner M, Dittrich F, Hughes RA, Thoenen H. Actions of CNTF and neurotrophins on degenerating motoneurons: preclinical studies and clinical implications. J Neurol Sci 1994; 124: S77-S83.
-
(1994)
J Neurol Sci
, vol.124
-
-
Sendtner, M.1
Dittrich, F.2
Hughes, R.A.3
Thoenen, H.4
-
194
-
-
0028262267
-
Neurotrophic growth factors and neurodegenerative diseases: Therapeutic potential of the neurotrophins and ciliary neurotrophic factor
-
Lindsay RM. Neurotrophic growth factors and neurodegenerative diseases: therapeutic potential of the neurotrophins and ciliary neurotrophic factor. Neurobiol Aging 1994; 15: 249-251
-
(1994)
Neurobiol Aging
, vol.15
, pp. 249-251
-
-
Lindsay, R.M.1
-
195
-
-
0034080807
-
The ciliary neurotrophic factor and its receptor, CNTFR alpha
-
Sleeman MW, Anderson KD, Lambert PD, Yancopoulos GD, Wiegand SJ. The ciliary neurotrophic factor and its receptor, CNTFR alpha. Pharma Acta Helv 2000; 74: 265-272
-
(2000)
Pharma Acta Helv
, vol.74
, pp. 265-272
-
-
Sleeman, M.W.1
Anderson, K.D.2
Lambert, P.D.3
Yancopoulos, G.D.4
Wiegand, S.J.5
-
196
-
-
0029940555
-
The neurotrophins and CNTF: Two families of collaborative neurotrophic factors
-
Ip NY, Yancopoulos GD. The neurotrophins and CNTF: two families of collaborative neurotrophic factors. Annu Rev Neurosci 1996; 19: 491-515.
-
(1996)
Annu Rev Neurosci
, vol.19
, pp. 491-515
-
-
Ip, N.Y.1
Yancopoulos, G.D.2
-
197
-
-
0034212562
-
Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia
-
Peterson WM, Wang Q, Tzekova R, Wiegand SJ. Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia. J Neurosci 2000; 20: 4081-4090
-
(2000)
J Neurosci
, vol.20
, pp. 4081-4090
-
-
Peterson, W.M.1
Wang, Q.2
Tzekova, R.3
Wiegand, S.J.4
-
198
-
-
0033536017
-
Synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor on cultured basal forebrain cholinergic neurons from postnatal 2-week-old rats
-
Hashimoto Y, Abiru Y, Nishio C, Hatanaka H. Synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor on cultured basal forebrain cholinergic neurons from postnatal 2-week-old rats. Brain Res Dev Brain Res 1999; 115: 25-32.
-
(1999)
Brain Res Dev Brain Res
, vol.115
, pp. 25-32
-
-
Hashimoto, Y.1
Abiru, Y.2
Nishio, C.3
Hatanaka, H.4
-
199
-
-
44949223642
-
CNTF: A putative link between dopamine D2 receptors and neurogenesis
-
Mori M, Jefferson JJ, Garbe DS. CNTF: A putative link between dopamine D2 receptors and neurogenesis. J Neurosci 2008; 28: 5867-5869
-
(2008)
J Neurosci
, vol.28
, pp. 5867-5869
-
-
Mori, M.1
Jefferson, J.J.2
Garbe, D.S.3
-
200
-
-
39849100457
-
Ciliary neurotrophic factor mediates dopamineD2 receptor-induced CNS neurogenesis in adult mice
-
Yang P, Arnold SA, Habas A, Hetman M, Hagg T. Ciliary neurotrophic factor mediates dopamineD2 receptor-induced CNS neurogenesis in adult mice. J Neurosci 2008; 28: 2231-2241
-
(2008)
J Neurosci
, vol.28
, pp. 2231-2241
-
-
Yang, P.1
Arnold, S.A.2
Habas, A.3
Hetman, M.4
Hagg, T.5
-
201
-
-
5644295321
-
Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: Results of a phase I study
-
Bloch J, Bachoud-Lévi AC, Déglon N, Lefaucheur JP, Winkel L, Palfi S, et al. Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study. Hum Gene Ther 2004; 15: 968-975
-
(2004)
Hum Gene Ther
, vol.15
, pp. 968-975
-
-
Bloch, J.1
Bachoud-Lévi, A.C.2
Déglon, N.3
Lefaucheur, J.P.4
Winkel, L.5
Palfi, S.6
-
202
-
-
33644872951
-
Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase I trial of CNTF delivered by encapsulated cell intraocular implants
-
Sieving PA, Caruso RC, Tao W, Coleman HR, Thompson DJ, Fullmer KR, et al. Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants. Proc Natl Acad Sci USA 2006; 103: 3896-3901
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3896-3901
-
-
Sieving, P.A.1
Caruso, R.C.2
Tao, W.3
Coleman, H.R.4
Thompson, D.J.5
Fullmer, K.R.6
-
203
-
-
33645735447
-
Intracompartmental delivery of CNTF as therapy for Huntinton's disease and retinitis pigmentosa
-
Emerich DF, Thanos CG. Intracompartmental delivery of CNTF as therapy for Huntinton's disease and retinitis pigmentosa. Curr Gene Ther 2006; 6: 147-159
-
(2006)
Curr Gene Ther
, vol.6
, pp. 147-159
-
-
Emerich, D.F.1
Thanos, C.G.2
-
204
-
-
38949156897
-
On the role of CNTF as a potential therapy for retinal degeneration: Dr. Jekyll or Mr. Hyde?
-
Beltran WA. On the role of CNTF as a potential therapy for retinal degeneration: Dr. Jekyll or Mr. Hyde? Adv Exp Med Biol 2008; 613: 45-51.
-
(2008)
Adv Exp Med Biol
, vol.613
, pp. 45-51
-
-
Beltran, W.A.1
-
205
-
-
64549131739
-
The insulin-like growth factor family: Molecular mechanisms, redox regulation and clinical implications
-
Vardatsikos G, Sahu A, Srivastava A. The insulin-like growth factor family: Molecular mechanisms, redox regulation and clinical implications. Antioxid Redox Signal 2009; 5: 1165-1190
-
(2009)
Antioxid Redox Signal
, vol.5
, pp. 1165-1190
-
-
Vardatsikos, G.1
Sahu, A.2
Srivastava, A.3
-
206
-
-
0028282528
-
Insulin-like growth factor-I receptors in human brain and pituitary gland: An autoradiographic study
-
De Keyser J, Wilczak N, De Backer JP, Herroelen L, Vauquelin G. Insulin-like growth factor-I receptors in human brain and pituitary gland: an autoradiographic study. Synapse 1994; 17: 196-202.
-
(1994)
Synapse
, vol.17
, pp. 196-202
-
-
De Keyser, J.1
Wilczak, N.2
De Backer, J.P.3
Herroelen, L.4
Vauquelin, G.5
-
207
-
-
34347377175
-
Distribution and localization patterns of estrogen receptor-β and insulin-like growth factor-1 receptors in neurons and glial cells of the female rat substantia nigra: Localization of ERβ and IGF-1R in substantia nigra
-
Quesada A, Romeo HE, Micevych P. Distribution and localization patterns of estrogen receptor-β and insulin-like growth factor-1 receptors in neurons and glial cells of the female rat substantia nigra: localization of ERβ and IGF-1R in substantia nigra. J Comp Neurol 2007; 503: 198-208.
-
(2007)
J Comp Neurol
, vol.503
, pp. 198-208
-
-
Quesada, A.1
Romeo, H.E.2
Micevych, P.3
-
208
-
-
47349112424
-
Similarities and differences between insulin and IGF-I: Structures, receptors, and signalling pathways
-
Werner H, Weinstein D, Bentov I. Similarities and differences between insulin and IGF-I: Structures, receptors, and signalling pathways. Arch Physiol Biochem 2008; 114: 17-22.
-
(2008)
Arch Physiol Biochem
, vol.114
, pp. 17-22
-
-
Werner, H.1
Weinstein, D.2
Bentov, I.3
-
209
-
-
0021873617
-
Insulin-like growth factors and insulin: Comparative aspects
-
Froesch ER, Zapf J. Insulin-like growth factors and insulin: comparative aspects. Diabetologia 1985; 28: 485-493
-
(1985)
Diabetologia
, vol.28
, pp. 485-493
-
-
Froesch, E.R.1
Zapf, J.2
-
210
-
-
65549099294
-
Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis
-
Li Y, Wu H, Khardori R, Song YH, Lu YW, Geng YJ. Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis. Biochem Biophys Res Commun 2009; 384: 259-264
-
(2009)
Biochem Biophys Res Commun
, vol.384
, pp. 259-264
-
-
Li, Y.1
Wu, H.2
Khardori, R.3
Song, Y.H.4
Lu, Y.W.5
Geng, Y.J.6
-
211
-
-
38449115019
-
Insulin-like growth factor-1 in plasma and brain: Regulation in health and disease
-
Sievers C, Schneider HJ, Stalla GK. Insulin-like growth factor-1 in plasma and brain: regulation in health and disease. Front Biosci 2008; 13: 85-99.
-
(2008)
Front Biosci
, vol.13
, pp. 85-99
-
-
Sievers, C.1
Schneider, H.J.2
Stalla, G.K.3
-
213
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001; 414: 799-806.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
214
-
-
33747121607
-
Insulin/IGF signalling in neurogenesis
-
Bateman JM, McNeill H. Insulin/IGF signalling in neurogenesis. Cell Mol Life Sci 2006; 63: 1701-1705
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 1701-1705
-
-
Bateman, J.M.1
McNeill, H.2
-
215
-
-
56649121807
-
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs
-
Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, et al. Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PLoS One 2008; 3: e3721.
-
(2008)
PLoS One
, vol.3
-
-
Broughton, S.1
Alic, N.2
Slack, C.3
Bass, T.4
Ikeya, T.5
Vinti, G.6
-
216
-
-
1842633868
-
The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease
-
Carro E, Torres-Aleman I. The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease. Eur J Pharmacol 2004; 490: 127-133
-
(2004)
Eur J Pharmacol
, vol.490
, pp. 127-133
-
-
Carro, E.1
Torres-Aleman, I.2
-
217
-
-
0034012017
-
Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway
-
Solano DC, Sironi M, Bonfini C, Solerte SB, Govoni S, Racchi M. Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway. FASEB J 2000; 14:1015-1022
-
(2000)
FASEB J
, vol.14
, pp. 1015-1022
-
-
Solano, D.C.1
Sironi, M.2
Bonfini, C.3
Solerte, S.B.4
Govoni, S.5
Racchi, M.6
-
218
-
-
0035871641
-
Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
-
Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, et al. Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci 2001; 21: 2561-2570
-
(2001)
J Neurosci
, vol.21
, pp. 2561-2570
-
-
Gasparini, L.1
Gouras, G.K.2
Wang, R.3
Gross, R.S.4
Beal, M.F.5
Greengard, P.6
-
219
-
-
0036917631
-
Serum insulin-like growth factor I regulates brain amyloid-β levels
-
Carro E, Trejo JL, Gomez-Isla T, LeRoith D, Torres-Aleman I. Serum insulin-like growth factor I regulates brain amyloid-β levels. Nat Med 2002; 8: 1390-1397
-
(2002)
Nat Med
, vol.8
, pp. 1390-1397
-
-
Carro, E.1
Trejo, J.L.2
Gomez-Isla, T.3
LeRoith, D.4
Torres-Aleman, I.5
-
220
-
-
0034638270
-
Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons
-
Lesort M, Johnson GVW. Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons. Neuroscience 2000; 99: 305-316
-
(2000)
Neuroscience
, vol.99
, pp. 305-316
-
-
Lesort, M.1
Johnson, G.V.W.2
-
221
-
-
59649083403
-
IGF-1 promotes β-amyloid production by a secretase-independent mechanism
-
Araki W, Kume H, Oda A, Tamaoka A, Kametani F. IGF-1 promotes β-amyloid production by a secretase-independent mechanism. Biochem Biophys Res Commun 2009; 380: 111-114
-
(2009)
Biochem Biophys Res Commun
, vol.380
, pp. 111-114
-
-
Araki, W.1
Kume, H.2
Oda, A.3
Tamaoka, A.4
Kametani, F.5
-
222
-
-
30344448866
-
Involvement of α1β1 integrin in insulin-like growth factor-1-mediated protection of PC12 neuronal processes from tumor necrosis factor-α-induced injury
-
Wang JY, Grabacka M, Marcinkiewicz C, Staniszewska I, Peruzzi F, Khalili K, et al. Involvement of α1β1 integrin in insulin-like growth factor-1-mediated protection of PC12 neuronal processes from tumor necrosis factor-α-induced injury. J Neurosci Res 2006; 83: 7-18.
-
(2006)
J Neurosci Res
, vol.83
, pp. 7-18
-
-
Wang, J.Y.1
Grabacka, M.2
Marcinkiewicz, C.3
Staniszewska, I.4
Peruzzi, F.5
Khalili, K.6
-
223
-
-
0034656167
-
Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus
-
Aberg MA, Aberg ND, Hedbäcker H, Oscarsson J, Eriksson PS. Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus. J Neurosci 2000; 20: 2896-2903
-
(2000)
J Neurosci
, vol.20
, pp. 2896-2903
-
-
Aberg, M.A.1
Aberg, N.D.2
Hedbäcker, H.3
Oscarsson, J.4
Eriksson, P.S.5
-
224
-
-
84924249462
-
-
http://clinicaltrials.gov
-
-
-
-
225
-
-
0035071725
-
Relationships between cortisol, dehydroepiandrosterone sulphate and insulin-like growth factor-I system in dementia
-
Murialdo G, Barreca A, Nobili F, Rollero A, Timossi G, Gianelli MV, et al. Relationships between cortisol, dehydroepiandrosterone sulphate and insulin-like growth factor-I system in dementia. J Endocrinol Invest 2001; 24: 139-146
-
(2001)
J Endocrinol Invest
, vol.24
, pp. 139-146
-
-
Murialdo, G.1
Barreca, A.2
Nobili, F.3
Rollero, A.4
Timossi, G.5
Gianelli, M.V.6
-
226
-
-
0037249113
-
Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs). Discovery of capromorelin
-
Carpino PA, Lefker BA, Toler SM, Pan LC, Hadcock JR, Cook ER, et al. Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs). Discovery of capromorelin. Bioorg Med Chem 2003; 11: 581-590
-
(2003)
Bioorg Med Chem
, vol.11
, pp. 581-590
-
-
Carpino, P.A.1
Lefker, B.A.2
Toler, S.M.3
Pan, L.C.4
Hadcock, J.R.5
Cook, E.R.6
-
227
-
-
0035079820
-
Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine growth hormone secretagogue
-
Pan LC, Carpino PA, Lefker BA, Ragan JA, Toler SM, Pettersen JC, et al. Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine growth hormone secretagogue. Endocrine 2001; 14: 121-132
-
(2001)
Endocrine
, vol.14
, pp. 121-132
-
-
Pan, L.C.1
Carpino, P.A.2
Lefker, B.A.3
Ragan, J.A.4
Toler, S.M.5
Pettersen, J.C.6
-
229
-
-
13144279277
-
Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke
-
Loddick SA, Liu XJ, Lu ZX, Liu C, Behan DP, Chalmers DC, et al. Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke. Proc Natl Acad Sci USA 1998; 95: 1894-1898
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1894-1898
-
-
Loddick, S.A.1
Liu, X.J.2
Lu, Z.X.3
Liu, C.4
Behan, D.P.5
Chalmers, D.C.6
-
230
-
-
73449091835
-
Mecasermin (recombinant human insulin-like growth factor I)
-
Rosenbloom AL. Mecasermin (recombinant human insulin-like growth factor I). Adv Ther 2009; 26: 40-54.
-
(2009)
Adv Ther
, vol.26
, pp. 40-54
-
-
Rosenbloom, A.L.1
-
231
-
-
58149242839
-
Subcutaneous IGF-1 is not beneficial in 2-year ALS trial
-
Sorenson EJ, Windbank AJ, Mandrekar JN, Bamlet WR, Appel SH, Armon C, et al. Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology 2008; 71: 1770-1775
-
(2008)
Neurology
, vol.71
, pp. 1770-1775
-
-
Sorenson, E.J.1
Windbank, A.J.2
Mandrekar, J.N.3
Bamlet, W.R.4
Appel, S.H.5
Armon, C.6
-
232
-
-
0042528664
-
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
-
Kaspar BK, Llado J, Sherkat N, Rothstein JD, Gage FH. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 2003; 301: 839-842
-
(2003)
Science
, vol.301
, pp. 839-842
-
-
Kaspar, B.K.1
Llado, J.2
Sherkat, N.3
Rothstein, J.D.4
Gage, F.H.5
-
233
-
-
33746849034
-
Neuroprotective agents for clinical trials in ALS: A systematic assessment
-
Traynor BJ, Bruijn L, Conwit R, Beal F, O'Neill G, Fagan SC, et al. Neuroprotective agents for clinical trials in ALS: a systematic assessment. Neurology 2006; 67; 20-27
-
(2006)
Neurology
, vol.67
, pp. 20-27
-
-
Traynor, B.J.1
Bruijn, L.2
Conwit, R.3
Beal, F.4
O'Neill, G.5
Fagan, S.C.6
-
234
-
-
0024805128
-
Nerve growth factor induces growth and differentiation of human B lymphocytes
-
Otten U, Ehrhard P, Peck R. Nerve growth factor induces growth and differentiation of human B lymphocytes. Proc Natl Acad Sci USA 1989; 86: 10059-10063
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 10059-10063
-
-
Otten, U.1
Ehrhard, P.2
Peck, R.3
-
235
-
-
40849146898
-
Nerve growth factor stimulates proliferation, adhesion and thymopoietic cytokine expression in mouse thymic epithelial cells in vitro
-
Lee HW, Na YJ, Jung PK, Kim MN, Kim SM, Chung JS, et al. Nerve growth factor stimulates proliferation, adhesion and thymopoietic cytokine expression in mouse thymic epithelial cells in vitro. Regul Pept 2008; 147: 72-81.
-
(2008)
Regul Pept
, vol.147
, pp. 72-81
-
-
Lee, H.W.1
Na, Y.J.2
Jung, P.K.3
Kim, M.N.4
Kim, S.M.5
Chung, J.S.6
-
236
-
-
38549128179
-
Neurotrophins modulate monocyte chemotaxis without affecting macrophage function
-
Samah B, Porcheray F, Gras G. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Clin Exp Immunol 2008; 151: 476-486
-
(2008)
Clin Exp Immunol
, vol.151
, pp. 476-486
-
-
Samah, B.1
Porcheray, F.2
Gras, G.3
-
237
-
-
0033103608
-
Activated human T cells, B cells, and monocytes produce brainderived neurotrophic factor in vitro and in inflammatory brain lesions: A neuroprotective role of inflammation?
-
Kerschensteiner M, Gallmeier E, Behrens L, Leal VV, Misgeld T, Klinkert WEF, et al. Activated human T cells, B cells, and monocytes produce brainderived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med 1999; 189: 865-870
-
(1999)
J Exp Med
, vol.189
, pp. 865-870
-
-
Kerschensteiner, M.1
Gallmeier, E.2
Behrens, L.3
Leal, V.V.4
Misgeld, T.5
Klinkert, W.E.F.6
-
238
-
-
0031950445
-
Expression of mRNA encoding neurotrophins and neurotrophin receptors in human granulocytes and bone marrow cells - Enhanced neurotrophin-4 expression induced by LTB4
-
Laurenzi MA, Beccari T, Stenke L, Sjolinder M, Stinchi S, Lindgren JA. Expression of mRNA encoding neurotrophins and neurotrophin receptors in human granulocytes and bone marrow cells - enhanced neurotrophin-4 expression induced by LTB4. J Leukoc Biol 1998; 64: 228-234
-
(1998)
J Leukoc Biol
, vol.64
, pp. 228-234
-
-
Laurenzi, M.A.1
Beccari, T.2
Stenke, L.3
Sjolinder, M.4
Stinchi, S.5
Lindgren, J.A.6
-
239
-
-
0030883308
-
Expression of functional TrkA receptor tyrosine kinase in the HMC-1 human mast cell line and in human mast cells
-
Tam SY, Tsai M, Yamaguchi M, Yano K, Butterfield JH, Galli SJ. Expression of functional TrkA receptor tyrosine kinase in the HMC-1 human mast cell line and in human mast cells. Blood 1997; 90: 1807-1820
-
(1997)
Blood
, vol.90
, pp. 1807-1820
-
-
Tam, S.Y.1
Tsai, M.2
Yamaguchi, M.3
Yano, K.4
Butterfield, J.H.5
Galli, S.J.6
-
240
-
-
50249144620
-
Differential upregulation of neurotrophin receptors and functional activity of neurotrophins on peripheral blood eosinophils of patients with allergic rhinitis, atopic dermatitis and nonatopic subjects
-
Raap U, Deneka N, Bruder M, Kapp A, Wedi B. Differential upregulation of neurotrophin receptors and functional activity of neurotrophins on peripheral blood eosinophils of patients with allergic rhinitis, atopic dermatitis and nonatopic subjects. Clin Exp Allergy 2008; 38: 1493-1498
-
(2008)
Clin Exp Allergy
, vol.38
, pp. 1493-1498
-
-
Raap, U.1
Deneka, N.2
Bruder, M.3
Kapp, A.4
Wedi, B.5
-
241
-
-
0041622813
-
The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma
-
Nassenstein C, Braun A, Erpenbeck VJ, Lommatzsch M, Schmidt S, Krug N, et al. The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma. J Exp Med 2003; 198: 455-467
-
(2003)
J Exp Med
, vol.198
, pp. 455-467
-
-
Nassenstein, C.1
Braun, A.2
Erpenbeck, V.J.3
Lommatzsch, M.4
Schmidt, S.5
Krug, N.6
-
242
-
-
0028137577
-
Ciliary neurotrophic factor: Pharmacokinetics and acute-phase response in rat
-
Dittrich F, Thoenen H, Sendtner M. Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat. Ann Neurol 1994; 35: 151-163
-
(1994)
Ann Neurol
, vol.35
, pp. 151-163
-
-
Dittrich, F.1
Thoenen, H.2
Sendtner, M.3
-
243
-
-
33746602640
-
Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis
-
Kuhlmann T, Remington L, Cognet I, Bourbonniere L, Zehntner S, Guilhot F, et al. Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis. Am J Pathol 2006; 169: 584-598
-
(2006)
Am J Pathol
, vol.169
, pp. 584-598
-
-
Kuhlmann, T.1
Remington, L.2
Cognet, I.3
Bourbonniere, L.4
Zehntner, S.5
Guilhot, F.6
-
244
-
-
0036281689
-
CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation
-
Linker RA, Mäurer M, Gaupp S, Martini R, Holtmann B, Giess R, et al. CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation. Nat Med 2002; 8: 620-624
-
(2002)
Nat Med
, vol.8
, pp. 620-624
-
-
Linker, R.A.1
Mäurer, M.2
Gaupp, S.3
Martini, R.4
Holtmann, B.5
Giess, R.6
-
245
-
-
0032211298
-
Changes of NGF presence in non-neuronal cells in response to experimental allergic encephalomyelitis in Lewis rats
-
Micera A, Vigneti E, Aloe L. Changes of NGF presence in non-neuronal cells in response to experimental allergic encephalomyelitis in Lewis rats. Exp Neurol 1998; 154: 41-46
-
(1998)
Exp Neurol
, vol.154
, pp. 41-46
-
-
Micera, A.1
Vigneti, E.2
Aloe, L.3
-
246
-
-
0034657843
-
Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system
-
Villoslada P, Hauser SL, Bartke I, Unger J, Heald N, Rosenberg D, et al. Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system. J Exp Med 2000; 191: 1799-1806
-
(2000)
J Exp Med
, vol.191
, pp. 1799-1806
-
-
Villoslada, P.1
Hauser, S.L.2
Bartke, I.3
Unger, J.4
Heald, N.5
Rosenberg, D.6
-
247
-
-
41949124799
-
Low and dysregulated BDNF secretion from immune cells of MS patients is related to reduced neuroprotection
-
Azoulay D, Urshansky N, Karni A. Low and dysregulated BDNF secretion from immune cells of MS patients is related to reduced neuroprotection. J Neuroimmunol 2008; 195: 186-193
-
(2008)
J Neuroimmunol
, vol.195
, pp. 186-193
-
-
Azoulay, D.1
Urshansky, N.2
Karni, A.3
-
248
-
-
59849118012
-
A longitudinal observation of brain-derived neurotrophic factor mRNA levels in patients with relapsing-remitting multiple sclerosis
-
Liguori M, Fera F, Patitucci A, Manna I, Condino F, Valentino P, et al. A longitudinal observation of brain-derived neurotrophic factor mRNA levels in patients with relapsing-remitting multiple sclerosis. Brain Res 2009; 1256: 123-128
-
(2009)
Brain Res
, vol.1256
, pp. 123-128
-
-
Liguori, M.1
Fera, F.2
Patitucci, A.3
Manna, I.4
Condino, F.5
Valentino, P.6
-
249
-
-
44649199252
-
Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis
-
Makar TK, Trisler D, Sura KT, Sultana S, Patel N, Bever CT. Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis. J Neurol Sci 2008; 270: 70-76
-
(2008)
J Neurol Sci
, vol.270
, pp. 70-76
-
-
Makar, T.K.1
Trisler, D.2
Sura, K.T.3
Sultana, S.4
Patel, N.5
Bever, C.T.6
-
250
-
-
41149125146
-
Neurodegeneration and inflammation
-
DeLegge MH, Smoke A. Neurodegeneration and inflammation. Nutr Clin Pract 2008; 23: 35-41.
-
(2008)
Nutr Clin Pract
, vol.23
, pp. 35-41
-
-
DeLegge, M.H.1
Smoke, A.2
-
251
-
-
54249124166
-
Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system
-
Dilger RN, Johnson RW. Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system. J Leukoc Biol 2008; 84: 932-939
-
(2008)
J Leukoc Biol
, vol.84
, pp. 932-939
-
-
Dilger, R.N.1
Johnson, R.W.2
-
252
-
-
23444443814
-
Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system
-
Godbout JP, Chen J, Abraham J, Richwine AF, Berg BM, Kelley KW, et al. Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system. FASEB J 2005; 19: 1329-1331
-
(2005)
FASEB J
, vol.19
, pp. 1329-1331
-
-
Godbout, J.P.1
Chen, J.2
Abraham, J.3
Richwine, A.F.4
Berg, B.M.5
Kelley, K.W.6
-
253
-
-
26244466228
-
The role of neurotrophins in brain aging: A perspective in honor of Regino Perez-Polo
-
Cotman CW. The role of neurotrophins in brain aging: a perspective in honor of Regino Perez-Polo. Neurochem Res 2005; 30: 877-881
-
(2005)
Neurochem Res
, vol.30
, pp. 877-881
-
-
Cotman, C.W.1
-
254
-
-
34547252566
-
Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: Function based and target-based discovery approaches
-
Van Eldik LJ, Thompson WL, Ralay Ranaivo H, Behanna HA, Martin Watterson D. Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: function based and target-based discovery approaches. Int Rev Neurobiol 2007; 82: 277-296
-
(2007)
Int Rev Neurobiol
, vol.82
, pp. 277-296
-
-
Van Eldik, L.J.1
Thompson, W.L.2
Ralay Ranaivo, H.3
Behanna, H.A.4
Martin Watterson, D.5
-
255
-
-
33646201107
-
TNF-α modulation for treatment of Alzheimer's disease: A 6-month pilot study
-
Tobinick E, Gross H, Weinberger A, Cohen H. TNF-α modulation for treatment of Alzheimer's disease: a 6-month pilot study. Med Gen Med 2006; 8: 25.
-
(2006)
Med Gen Med
, vol.8
, pp. 25
-
-
Tobinick, E.1
Gross, H.2
Weinberger, A.3
Cohen, H.4
-
256
-
-
38549178015
-
Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration
-
Tobinick EL, Gross H. Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration. J Neuroinflam 2008; 5: 2.
-
(2008)
J Neuroinflam
, vol.5
, pp. 2
-
-
Tobinick, E.L.1
Gross, H.2
-
257
-
-
49949104408
-
Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer's disease
-
Tobinick EL, Gross H. Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer's disease. BMC Neurol 2008; 8: 27.
-
(2008)
BMC Neurol
, vol.8
, pp. 27
-
-
Tobinick, E.L.1
Gross, H.2
-
258
-
-
39349087157
-
Perispinal etanercept: Potential as an Alzheimer therapeutic
-
Griffin WS. Perispinal etanercept: potential as an Alzheimer therapeutic. J Neuroinflam 2008; 5: 3.
-
(2008)
J Neuroinflam
, vol.5
, pp. 3
-
-
Griffin, W.S.1
-
259
-
-
0026729733
-
Restoration of ascending noradrenergic projections by residual locus coeruleus neurons: Compensatory response to neurotoxin-induced cell death in the adult rat brain
-
Fritschy JM, Grzanna R. Restoration of ascending noradrenergic projections by residual locus coeruleus neurons: compensatory response to neurotoxin-induced cell death in the adult rat brain. J Comp Neurol 1992; 321: 421-441
-
(1992)
J Comp Neurol
, vol.321
, pp. 421-441
-
-
Fritschy, J.M.1
Grzanna, R.2
-
260
-
-
0028953736
-
Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury - II. Reactive expression of the nerve growth factor gene in astrocytes
-
Arendt T, Brückner MK, Krell T, Pagliusi S, Kruska L, Heumann R. Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury - II. Reactive expression of the nerve growth factor gene in astrocytes. Neuroscience 1995; 65: 647-659
-
(1995)
Neuroscience
, vol.65
, pp. 647-659
-
-
Arendt, T.1
Brückner, M.K.2
Krell, T.3
Pagliusi, S.4
Kruska, L.5
Heumann, R.6
-
261
-
-
0023514236
-
Alzheimer's disease as a presumptive threshold phenomenon
-
Arendt T, Bigl V. Alzheimer's disease as a presumptive threshold phenomenon. Neurobiol Aging 1987; 8: 552-554
-
(1987)
Neurobiol Aging
, vol.8
, pp. 552-554
-
-
Arendt, T.1
Bigl, V.2
-
262
-
-
0029639824
-
Dendritic reorganisation in the basal forebrain under degenerative conditions and its defects in Alzheimer's disease. I. Dendritic organisation of the normal human basal forebrain
-
Arendt T, Marcova L, Bigl V, Brückner MK. Dendritic reorganisation in the basal forebrain under degenerative conditions and its defects in Alzheimer's disease. I. Dendritic organisation of the normal human basal forebrain. J Comp Neurol 1995; 351: 169-188
-
(1995)
J Comp Neurol
, vol.351
, pp. 169-188
-
-
Arendt, T.1
Marcova, L.2
Bigl, V.3
Brückner, M.K.4
-
263
-
-
0028945009
-
Dendritic reorganisation in the basal forebrain under degenerative conditions and its defects in Alzheimer's disease. II. Ageing, Korsakoff's disease, Parkinson's disease, and Alzheimer's disease
-
Arendt T, Brückner MK, Bigl V, Marcova L. Dendritic reorganisation in the basal forebrain under degenerative conditions and its defects in Alzheimer's disease. II. Ageing, Korsakoff's disease, Parkinson's disease, and Alzheimer's disease. J Comp Neurol 1995; 351: 189-222.
-
(1995)
J Comp Neurol
, vol.351
, pp. 189-222
-
-
Arendt, T.1
Brückner, M.K.2
Bigl, V.3
Marcova, L.4
-
264
-
-
40849138306
-
Rapid synaptic scaling induced by changes in postsynaptic firing
-
Ibata K, Sun Q, Turrigiano GG. Rapid synaptic scaling induced by changes in postsynaptic firing. Neuron 2008; 57: 819-826
-
(2008)
Neuron
, vol.57
, pp. 819-826
-
-
Ibata, K.1
Sun, Q.2
Turrigiano, G.G.3
-
265
-
-
0028080782
-
Activity-dependent current distributions in model neurons
-
Siegel M, Marder E, Abbott LF. Activity-dependent current distributions in model neurons. Proc Natl Acad Sci USA 1994; 91: 11308-11312
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11308-11312
-
-
Siegel, M.1
Marder, E.2
Abbott, L.F.3
-
266
-
-
0024535331
-
Excitatory and inhibitory neurotransmitters in the generation and degeneration of hippocampal neuroarchitecture
-
Mattson MP, Kater SB. Excitatory and inhibitory neurotransmitters in the generation and degeneration of hippocampal neuroarchitecture. Brain Res 1989; 478: 337-348
-
(1989)
Brain Res
, vol.478
, pp. 337-348
-
-
Mattson, M.P.1
Kater, S.B.2
-
268
-
-
0346787871
-
Neuroprotection in cerebral ischaemia: Facts and fancies - The need for new approaches
-
Wahlgren NG, Ahmed N. Neuroprotection in cerebral ischaemia: facts and fancies - the need for new approaches. Cerebrovasc Dis 2004; 17: 153-166
-
(2004)
Cerebrovasc Dis
, vol.17
, pp. 153-166
-
-
Wahlgren, N.G.1
Ahmed, N.2
-
269
-
-
0034625581
-
Intracerebroventricular infusion of nerve growth factor induces pain like response in rats
-
Hao J, Ebendal T, Xu X, Wiesenfeld-Hallin Z, Eriksdotter Jonhagen M. Intracerebroventricular infusion of nerve growth factor induces pain like response in rats. Neurosci Lett 2000; 286: 208-212
-
(2000)
Neurosci Lett
, vol.286
, pp. 208-212
-
-
Hao, J.1
Ebendal, T.2
Xu, X.3
Wiesenfeld-Hallin, Z.4
Eriksdotter Jonhagen, M.5
-
270
-
-
0036444020
-
Modulation of sensory inputs and ectopic presence of Schwann cells depend upon the route and duration of nerve growth factor administration
-
Pizzo DP, Winkler J, Sidiqi I, Waite JJ, Thal LJ. Modulation of sensory inputs and ectopic presence of Schwann cells depend upon the route and duration of nerve growth factor administration. Exp Neurol 2002; 178: 91-103.
-
(2002)
Exp Neurol
, vol.178
, pp. 91-103
-
-
Pizzo, D.P.1
Winkler, J.2
Sidiqi, I.3
Waite, J.J.4
Thal, L.J.5
-
271
-
-
0032528159
-
Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord
-
McTigue DM, Horner PJ, Stokes BT, Gage FH. Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. J Neurosci 1998; 18: 5354-5365
-
(1998)
J Neurosci
, vol.18
, pp. 5354-5365
-
-
McTigue, D.M.1
Horner, P.J.2
Stokes, B.T.3
Gage, F.H.4
-
272
-
-
33744994565
-
Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death
-
Massa SM, Xie Y, Yang T, Harrington AW, Kim ML, Yoon SO, et al. Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death. J Neurosci 2006; 26: 5288-5300
-
(2006)
J Neurosci
, vol.26
, pp. 5288-5300
-
-
Massa, S.M.1
Xie, Y.2
Yang, T.3
Harrington, A.W.4
Kim, M.L.5
Yoon, S.O.6
-
273
-
-
3142752927
-
Neurotrophins: Novel mediators of angiogenesis
-
Kraemer R, Hempstead BL. Neurotrophins: novel mediators of angiogenesis. Front Biosci 2003; 8: S1181-S6.
-
(2003)
Front Biosci
, vol.8
-
-
Kraemer, R.1
Hempstead, B.L.2
-
274
-
-
0035496986
-
NGF, BDNF, leptin, and mast cells in human coronary atherosclerosis and metabolic syndrome
-
Chaldakov GN, Fiore M, Stankulov IS, Hristova M, Antonelli A, Manni L, et al. NGF, BDNF, leptin, and mast cells in human coronary atherosclerosis and metabolic syndrome. Arch Physiol Biochem 2001; 109: 357-360
-
(2001)
Arch Physiol Biochem
, vol.109
, pp. 357-360
-
-
Chaldakov, G.N.1
Fiore, M.2
Stankulov, I.S.3
Hristova, M.4
Antonelli, A.5
Manni, L.6
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