메뉴 건너뛰기




Volumn 380, Issue 1, 2009, Pages 111-114

IGF-1 promotes β-amyloid production by a secretase-independent mechanism

Author keywords

Amyloid; Alzheimer's disease; IGF 1; Neuroblastoma; Phosphorylation

Indexed keywords

ALANINE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE INHIBITOR; SECRETASE; SOMATOMEDIN C;

EID: 59649083403     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.01.044     Document Type: Article
Times cited : (26)

References (34)
  • 1
    • 0036855661 scopus 로고    scopus 로고
    • Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease
    • Selkoe D.J. Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease. J. Clin. Invest. 110 (2002) 1375-1381
    • (2002) J. Clin. Invest. , vol.110 , pp. 1375-1381
    • Selkoe, D.J.1
  • 2
    • 1442264828 scopus 로고    scopus 로고
    • Take five-BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation
    • Haass C. Take five-BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation. EMBO J. 23 (2004) 483-488
    • (2004) EMBO J. , vol.23 , pp. 483-488
    • Haass, C.1
  • 5
    • 0034518163 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway
    • Zheng W.H., Kar S., Doré S., and Quirion R. Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway. J. Neural Transm. Suppl. 60 (2000) 261-272
    • (2000) J. Neural Transm. Suppl. , vol.60 , pp. 261-272
    • Zheng, W.H.1    Kar, S.2    Doré, S.3    Quirion, R.4
  • 6
    • 0142026832 scopus 로고    scopus 로고
    • Potential roles of insulin and IGF-1 in Alzheimer's disease
    • Gasparini L., and Xu H. Potential roles of insulin and IGF-1 in Alzheimer's disease. Ternds Neurosci. 26 (2003) 404-406
    • (2003) Ternds Neurosci. , vol.26 , pp. 404-406
    • Gasparini, L.1    Xu, H.2
  • 7
    • 1842633868 scopus 로고    scopus 로고
    • The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease
    • Carro E., and Torres-Aleman I. The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease. Eur. J. Pharmacol. 490 (2004) 127-133
    • (2004) Eur. J. Pharmacol. , vol.490 , pp. 127-133
    • Carro, E.1    Torres-Aleman, I.2
  • 8
    • 0035871641 scopus 로고    scopus 로고
    • Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling
    • Gasparini L., Gouras G.K., Wang R., Gross R.S., Beal M.F., Greengard P., and Xu H. Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J. Neurosci. 21 (2001) 2561-2570
    • (2001) J. Neurosci. , vol.21 , pp. 2561-2570
    • Gasparini, L.1    Gouras, G.K.2    Wang, R.3    Gross, R.S.4    Beal, M.F.5    Greengard, P.6    Xu, H.7
  • 9
    • 33644591150 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine
    • Rivera E.J., Goldin A., Fulmer N., Tavares R., Wands J.R., and de la Monte S.M. Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J. Alzheimer's Dis. 8 (2005) 247-268
    • (2005) J. Alzheimer's Dis. , vol.8 , pp. 247-268
    • Rivera, E.J.1    Goldin, A.2    Fulmer, N.3    Tavares, R.4    Wands, J.R.5    de la Monte, S.M.6
  • 10
    • 33847140273 scopus 로고    scopus 로고
    • Serum TNF-alpha levels are increased and correlate negatively with free IGF-I in Alzheimer disease
    • Alvarez A., Cacabelos R., Sanpedro C., García-Fantini M., and Aleixandre M. Serum TNF-alpha levels are increased and correlate negatively with free IGF-I in Alzheimer disease. Neurobiol. Aging 28 (2007) 533-536
    • (2007) Neurobiol. Aging , vol.28 , pp. 533-536
    • Alvarez, A.1    Cacabelos, R.2    Sanpedro, C.3    García-Fantini, M.4    Aleixandre, M.5
  • 11
    • 39049165846 scopus 로고    scopus 로고
    • Use of serum insulin-like growth factor-I levels to predict psychiatric non-response to donepezil in patients with Alzheimer's disease
    • Tei E., Yamamoto H., Watanabe T., Miyazaki A., Nakadate T., Kato N., and Mimura M. Use of serum insulin-like growth factor-I levels to predict psychiatric non-response to donepezil in patients with Alzheimer's disease. Growth Horm. IGF Res. 18 (2008) 47-54
    • (2008) Growth Horm. IGF Res. , vol.18 , pp. 47-54
    • Tei, E.1    Yamamoto, H.2    Watanabe, T.3    Miyazaki, A.4    Nakadate, T.5    Kato, N.6    Mimura, M.7
  • 12
    • 1542543460 scopus 로고    scopus 로고
    • Gamma-secretase can cleave amyloid precursor protein fragments independent of alpha- and beta-secretase pre-cutting
    • Kume H., Maruyama K., and Kametani F. Gamma-secretase can cleave amyloid precursor protein fragments independent of alpha- and beta-secretase pre-cutting. Int. J. Mol. Med. 13 (2004) 121-125
    • (2004) Int. J. Mol. Med. , vol.13 , pp. 121-125
    • Kume, H.1    Maruyama, K.2    Kametani, F.3
  • 13
    • 33748755837 scopus 로고    scopus 로고
    • Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein
    • Murayama K.S., Kametani F., Saito S., Kume H., Akiyama H., and Araki W. Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein. Eur. J. Neurosci. 24 (2006) 1237-1244
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 1237-1244
    • Murayama, K.S.1    Kametani, F.2    Saito, S.3    Kume, H.4    Akiyama, H.5    Araki, W.6
  • 14
    • 0842287198 scopus 로고    scopus 로고
    • Enhanced generation of intracellular Abeta42 amyloid peptide by mutation of presenilins PS1 and PS2
    • Takeda K., Araki W., and Tabira T. Enhanced generation of intracellular Abeta42 amyloid peptide by mutation of presenilins PS1 and PS2. Eur. J. Neurosci. 19 (2004) 258-264
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 258-264
    • Takeda, K.1    Araki, W.2    Tabira, T.3
  • 15
    • 0027202676 scopus 로고
    • Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks beta/A4 amyloid immunoreactivity
    • Kametani F., Tanaka K., Ishii T., Ikeda S., Kennedy H.E., and Allsop D. Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks beta/A4 amyloid immunoreactivity. Biochem. Biophys. Res. Commun. 191 (1993) 392-398
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 392-398
    • Kametani, F.1    Tanaka, K.2    Ishii, T.3    Ikeda, S.4    Kennedy, H.E.5    Allsop, D.6
  • 18
    • 0035659414 scopus 로고    scopus 로고
    • Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons
    • Araki W., Yuasa K., Takeda S., Takeda K., Shirotani K., Takahashi K., and Tabira T. Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons. J. Neurochem. 79 (2001) 1161-1168
    • (2001) J. Neurochem. , vol.79 , pp. 1161-1168
    • Araki, W.1    Yuasa, K.2    Takeda, S.3    Takeda, K.4    Shirotani, K.5    Takahashi, K.6    Tabira, T.7
  • 19
    • 0942290417 scopus 로고    scopus 로고
    • Insulin-like growth factor-I signaling in human neuroblastoma cells
    • Kim B., van Golen C.M., and Feldman E.L. Insulin-like growth factor-I signaling in human neuroblastoma cells. Oncogene 23 (2004) 130-141
    • (2004) Oncogene , vol.23 , pp. 130-141
    • Kim, B.1    van Golen, C.M.2    Feldman, E.L.3
  • 20
    • 9444236758 scopus 로고    scopus 로고
    • Amino-truncated amyloid beta-peptide (Abeta5-40/42) produced from caspase-cleaved amyloid precursor protein is deposited in Alzheimer's disease brain
    • Takeda K., Araki W., Akiyama H., and Tabira T. Amino-truncated amyloid beta-peptide (Abeta5-40/42) produced from caspase-cleaved amyloid precursor protein is deposited in Alzheimer's disease brain. FASEB J. 18 (2004) 1755-1757
    • (2004) FASEB J. , vol.18 , pp. 1755-1757
    • Takeda, K.1    Araki, W.2    Akiyama, H.3    Tabira, T.4
  • 21
    • 12844282223 scopus 로고    scopus 로고
    • Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site
    • Flood F., Murphy S., Cowburn R.F., Lannfelt L., Walker B., and Johnston J.A. Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site. Biochem. J. 385 (2005) 545-550
    • (2005) Biochem. J. , vol.385 , pp. 545-550
    • Flood, F.1    Murphy, S.2    Cowburn, R.F.3    Lannfelt, L.4    Walker, B.5    Johnston, J.A.6
  • 23
    • 33646591261 scopus 로고    scopus 로고
    • An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation
    • Costantini C., Scrable H., and Puglielli L. An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation. EMBO J. 35 (2006) 1997-2006
    • (2006) EMBO J. , vol.35 , pp. 1997-2006
    • Costantini, C.1    Scrable, H.2    Puglielli, L.3
  • 24
    • 0036669037 scopus 로고    scopus 로고
    • Control of cell survival by IGF signaling pathways
    • Vincent A.M., and Feldman E.L. Control of cell survival by IGF signaling pathways. Growth Horm. IGF Res. 12 (2002) 193-197
    • (2002) Growth Horm. IGF Res. , vol.12 , pp. 193-197
    • Vincent, A.M.1    Feldman, E.L.2
  • 25
    • 34249851328 scopus 로고    scopus 로고
    • IGF-1-induced processing of the amyloid precursor protein family is mediated by different signaling pathways
    • Adlerz L., Holback S., Multhaup G., and Iverfeldt K. IGF-1-induced processing of the amyloid precursor protein family is mediated by different signaling pathways. J. Biol. Chem. 282 (2007) 10203-10209
    • (2007) J. Biol. Chem. , vol.282 , pp. 10203-10209
    • Adlerz, L.1    Holback, S.2    Multhaup, G.3    Iverfeldt, K.4
  • 28
    • 0037966577 scopus 로고    scopus 로고
    • Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/Cdk5 and p25/Cdk5
    • Liu F., Su Y., Li B., Zhou Y., Ryder J., Gonzalez-DeWhitt P., May P.C., and Ni B. Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/Cdk5 and p25/Cdk5. FEBS Lett. 547 (2003) 193-196
    • (2003) FEBS Lett. , vol.547 , pp. 193-196
    • Liu, F.1    Su, Y.2    Li, B.3    Zhou, Y.4    Ryder, J.5    Gonzalez-DeWhitt, P.6    May, P.C.7    Ni, B.8
  • 29
    • 0035166824 scopus 로고    scopus 로고
    • Phosphorylation of thr(668) in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress-activated protein kinase 1b (Jun N-terminal kinase-3)
    • Standen C.L., Brownlees J., Grierson A.J., Kesavapany S., Lau K.F., McLoughlin D.M., and Miller C.C. Phosphorylation of thr(668) in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress-activated protein kinase 1b (Jun N-terminal kinase-3). J. Neurochem. 76 (2001) 316-320
    • (2001) J. Neurochem. , vol.76 , pp. 316-320
    • Standen, C.L.1    Brownlees, J.2    Grierson, A.J.3    Kesavapany, S.4    Lau, K.F.5    McLoughlin, D.M.6    Miller, C.C.7
  • 30
    • 17644427740 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase-interacting protein-3 facilitates phosphorylation and controls localization of amyloid-beta precursor protein
    • Muresan Z., and Muresan V. c-Jun NH2-terminal kinase-interacting protein-3 facilitates phosphorylation and controls localization of amyloid-beta precursor protein. J. Neurosci. 25 (2005) 3741-3751
    • (2005) J. Neurosci. , vol.25 , pp. 3741-3751
    • Muresan, Z.1    Muresan, V.2
  • 31
    • 39749196069 scopus 로고    scopus 로고
    • Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease
    • Ryoo S.R., Cho H.J., Lee H.W., Jeong H.K., Radnaabazar C., Kim Y.S., Kim M.J., Son M.Y., Seo H., Chung S.H., and Song W.J. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease. J. Neurochem. 104 (2008) 1333-1344
    • (2008) J. Neurochem. , vol.104 , pp. 1333-1344
    • Ryoo, S.R.1    Cho, H.J.2    Lee, H.W.3    Jeong, H.K.4    Radnaabazar, C.5    Kim, Y.S.6    Kim, M.J.7    Son, M.Y.8    Seo, H.9    Chung, S.H.10    Song, W.J.11
  • 32
    • 0036917631 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I regulates brain amyloid-beta levels
    • Carro E., Trejo J.L., Gomez-Isla T., LeRoith D., and Torres-Aleman I. Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat. Med. 8 (2002) 1390-1397
    • (2002) Nat. Med. , vol.8 , pp. 1390-1397
    • Carro, E.1    Trejo, J.L.2    Gomez-Isla, T.3    LeRoith, D.4    Torres-Aleman, I.5
  • 34
    • 58149260966 scopus 로고    scopus 로고
    • MK-677 protocol 30 study group, growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial
    • Sevigny J.J., Ryan J.M., van Dyck C.H., Peng Y., Lines C.R., and Nessly M.L. MK-677 protocol 30 study group, growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial. Neurology 71 (2008) 1702-1708
    • (2008) Neurology , vol.71 , pp. 1702-1708
    • Sevigny, J.J.1    Ryan, J.M.2    van Dyck, C.H.3    Peng, Y.4    Lines, C.R.5    Nessly, M.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.