-
1
-
-
0037059330
-
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
-
Aguirre V., Werner E.D., Giraud J., Lee Y.H., Shoelson S.E., White M.F. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J. Biol. Chem. 277:2002;1531-1537.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1531-1537
-
-
Aguirre, V.1
Werner, E.D.2
Giraud, J.3
Lee, Y.H.4
Shoelson, S.E.5
White, M.F.6
-
2
-
-
0033010160
-
Insulin-like growth factor-I and cognitive function in healthy older men
-
Aleman A., Verhaar H.J., de Haan E.H., de Vries W.R., Samson M.M., Drent M.L., van der Veen E.A., Koppeschaar H.P. Insulin-like growth factor-I and cognitive function in healthy older men. J. Clin. Endocrinol. Metab. 84:1999;471-475.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 471-475
-
-
Aleman, A.1
Verhaar, H.J.2
De Haan, E.H.3
De Vries, W.R.4
Samson, M.M.5
Drent, M.L.6
Van Der Veen, E.A.7
Koppeschaar, H.P.8
-
3
-
-
0030772513
-
IGF-1 modulates N and L calcium channels in a PI 3-kinase-dependent manner
-
Blair L.A., Marshall J. IGF-1 modulates N and L calcium channels in a PI 3-kinase-dependent manner. Neuron. 19:1997;421-429.
-
(1997)
Neuron
, vol.19
, pp. 421-429
-
-
Blair, L.A.1
Marshall, J.2
-
4
-
-
0029414741
-
Altered regulation of brain glucose metabolism as a cause of neurodegenerative disorders?
-
Blum-Degen D., Frolich L., Hoyer S., Riederer P. Altered regulation of brain glucose metabolism as a cause of neurodegenerative disorders? J. Neural Transm. (Suppl. 46):1995;139-147.
-
(1995)
J. Neural Transm.
, vol.46
, Issue.SUPPL.
, pp. 139-147
-
-
Blum-Degen, D.1
Frolich, L.2
Hoyer, S.3
Riederer, P.4
-
5
-
-
0036370630
-
Insulin-like growth factor-1 promotes neuronal glucose utilization during brain development and repair processes
-
Bondy C.A., Cheng C.M. Insulin-like growth factor-1 promotes neuronal glucose utilization during brain development and repair processes. Int. Rev. Neurobiol. 51:2002;189-217.
-
(2002)
Int. Rev. Neurobiol.
, vol.51
, pp. 189-217
-
-
Bondy, C.A.1
Cheng, C.M.2
-
6
-
-
0025933857
-
Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1), IGF-1 gene expression, and IGF-1 binding proteins
-
Breese C.R., Ingram R.L., Sonntag W.E. Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1), IGF-1 gene expression, and IGF-1 binding proteins. J. Gerontol. 46:1991;B180-B187.
-
(1991)
J. Gerontol.
, vol.46
-
-
Breese, C.R.1
Ingram, R.L.2
Sonntag, W.E.3
-
7
-
-
0033163270
-
A high plasma concentration of TNF-alpha is associated with dementia in centenarians
-
Bruunsgaard H., Andersen-Ranberg K., Jeune B., Pedersen A.N., Skinhoj P., Pedersen B.K. A high plasma concentration of TNF-alpha is associated with dementia in centenarians. J. Gerontol., Ser. A, Biol. Sci. Med. Sci. 54:1999;M357-M364.
-
(1999)
J. Gerontol., Ser. A, Biol. Sci. Med. Sci.
, vol.54
-
-
Bruunsgaard, H.1
Andersen-Ranberg, K.2
Jeune, B.3
Pedersen, A.N.4
Skinhoj, P.5
Pedersen, B.K.6
-
8
-
-
0034520593
-
Neurodegeneration is associated to changes in serum insulin-like growth factors
-
Busiguina S., Fernandez A.M., Barrios V., Clark R., Tolbert D.L., Berciano J., Torres-Aleman I. Neurodegeneration is associated to changes in serum insulin-like growth factors. Neurobiol. Dis. 7:2000;657-665.
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 657-665
-
-
Busiguina, S.1
Fernandez, A.M.2
Barrios, V.3
Clark, R.4
Tolbert, D.L.5
Berciano, J.6
Torres-Aleman, I.7
-
9
-
-
0345862282
-
Insulin-like growth factor I and Alzheimer's disease: Therapeutic prospects?
-
Carro E.M.et al. Insulin-like growth factor I and Alzheimer's disease: therapeutic prospects? Exp. Rev. Neurother. 4:2003;79-86.
-
(2003)
Exp. Rev. Neurother.
, vol.4
, pp. 79-86
-
-
Carro, E.M.1
-
10
-
-
18144446836
-
Circulating insulin-like growth factor I mediates effects of exercise on the brain
-
Carro E., Nunez A., Busiguina S., Torres-Aleman I. Circulating insulin-like growth factor I mediates effects of exercise on the brain. J. Neurosci. 20:2000;2926-2933.
-
(2000)
J. Neurosci.
, vol.20
, pp. 2926-2933
-
-
Carro, E.1
Nunez, A.2
Busiguina, S.3
Torres-Aleman, I.4
-
11
-
-
0036917631
-
Serum insulin-like growth factor I regulates brain amyloid-beta levels
-
Carro E., Trejo J.L., Gomez-Isla T., LeRoith D., Torres-Aleman I. Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat. Med. 8:2002;1390-1397.
-
(2002)
Nat. Med.
, vol.8
, pp. 1390-1397
-
-
Carro, E.1
Trejo, J.L.2
Gomez-Isla, T.3
Leroith, D.4
Torres-Aleman, I.5
-
12
-
-
0027297106
-
Long-term depression of glutamate-induced gamma-aminobutyric acid release in cerebellum by insulin-like growth factor I
-
Castro-Alamancos M.A., Torres-Aleman I. Long-term depression of glutamate-induced gamma-aminobutyric acid release in cerebellum by insulin-like growth factor I. Proc. Natl. Acad. Sci. U. S. A. 90:1993;7386-7390.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 7386-7390
-
-
Castro-Alamancos, M.A.1
Torres-Aleman, I.2
-
13
-
-
0037418570
-
Alzheimer disease: Current concepts and emerging diagnostic and therapeutic strategies
-
Clark C.M., Karlawish J.H. Alzheimer disease: current concepts and emerging diagnostic and therapeutic strategies. Ann. Intern. Med. 138:2003;400-410.
-
(2003)
Ann. Intern. Med.
, vol.138
, pp. 400-410
-
-
Clark, C.M.1
Karlawish, J.H.2
-
14
-
-
0031907459
-
Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein e genotype
-
Craft S., Peskind E., Schwartz M.W., Schellenberg G.D., Raskind M., Porte D. Jr. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology. 50:1998;164-168.
-
(1998)
Neurology
, vol.50
, pp. 164-168
-
-
Craft, S.1
Peskind, E.2
Schwartz, M.W.3
Schellenberg, G.D.4
Raskind, M.5
Porte Jr., D.6
-
15
-
-
0032841571
-
Insulin metabolism in Alzheimer's disease differs according to apolipoprotein e genotype and gender
-
Craft S., Asthana S., Schellenberg G., Cherrier M., Baker L.D., Newcomer J., Plymate S., LaTendresse S., Petrova A., Raskind M., Peskind E., Lofgreen C., Grimwood K. Insulin metabolism in Alzheimer's disease differs according to apolipoprotein E genotype and gender. Neuroendocrinology. 70:1999;146-152.
-
(1999)
Neuroendocrinology
, vol.70
, pp. 146-152
-
-
Craft, S.1
Asthana, S.2
Schellenberg, G.3
Cherrier, M.4
Baker, L.D.5
Newcomer, J.6
Plymate, S.7
Latendresse, S.8
Petrova, A.9
Raskind, M.10
Peskind, E.11
Lofgreen, C.12
Grimwood, K.13
-
16
-
-
0034016848
-
Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype
-
Craft S., Asthana S., Schellenberg G., Baker L., Cherrier M., Boyt A.A., Martins R.N., Raskind M., Peskind E., Plymate S. Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype. Ann. N. Y. Acad. Sci. 903:2000;222-228.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.903
, pp. 222-228
-
-
Craft, S.1
Asthana, S.2
Schellenberg, G.3
Baker, L.4
Cherrier, M.5
Boyt, A.A.6
Martins, R.N.7
Raskind, M.8
Peskind, E.9
Plymate, S.10
-
17
-
-
0028814675
-
The developing CNS: A scenario for the action of proinsulin, insulin and insulin-like growth factors
-
de Pablo F., de la Rosa E.J. The developing CNS: a scenario for the action of proinsulin, insulin and insulin-like growth factors. Trends Neurosci. 18:1995;143-150.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 143-150
-
-
De Pablo, F.1
De La Rosa, E.J.2
-
18
-
-
0035153262
-
Involvement of the choroid plexus in central nervous system inflammation
-
Engelhardt B., Wolburg-Buchholz K., Wolburg H. Involvement of the choroid plexus in central nervous system inflammation. Microsc. Res. Tech. 52:2001;112-129.
-
(2001)
Microsc. Res. Tech.
, vol.52
, pp. 112-129
-
-
Engelhardt, B.1
Wolburg-Buchholz, K.2
Wolburg, H.3
-
19
-
-
0034093140
-
Brain insulin receptor causes activity-dependent current suppression in the olfactory bulb through multiple phosphorylation of Kv1.3
-
Fadool D.A., Tucker K., Phillips J.J., Simmen J.A. Brain insulin receptor causes activity-dependent current suppression in the olfactory bulb through multiple phosphorylation of Kv1.3. J. Neurophysiol. 83:2000;2332-2348.
-
(2000)
J. Neurophysiol.
, vol.83
, pp. 2332-2348
-
-
Fadool, D.A.1
Tucker, K.2
Phillips, J.J.3
Simmen, J.A.4
-
20
-
-
0037390039
-
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo
-
Farris W., Mansourian S., Chang Y., Lindsley L., Eckman E.A., Frosch M.P., Eckman C.B., Tanzi R.E., Selkoe D.J., Guenette S. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc. Natl. Acad. Sci. U. S. A. 100:2003;4162-4167.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 4162-4167
-
-
Farris, W.1
Mansourian, S.2
Chang, Y.3
Lindsley, L.4
Eckman, E.A.5
Frosch, M.P.6
Eckman, C.B.7
Tanzi, R.E.8
Selkoe, D.J.9
Guenette, S.10
-
21
-
-
18244413454
-
Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly
-
Federici M., Giaccari A., Hribal M.L., Giovannone B., Lauro D., Morviducci L., Pastore L., Tamburrano G., Lauro R., Sesti G. Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly. Diabetes. 48:1999;2277-2285.
-
(1999)
Diabetes
, vol.48
, pp. 2277-2285
-
-
Federici, M.1
Giaccari, A.2
Hribal, M.L.3
Giovannone, B.4
Lauro, D.5
Morviducci, L.6
Pastore, L.7
Tamburrano, G.8
Lauro, R.9
Sesti, G.10
-
22
-
-
0035425234
-
Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes
-
Fernandez A.M., Kim J.K., Yakar S., Dupont J., Hernandez-Sanchez C., Castle A.L., Filmore J., Shulman G.I., Le Roith D. Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes. Genes Dev. 15:2001;1926-1934.
-
(2001)
Genes Dev.
, vol.15
, pp. 1926-1934
-
-
Fernandez, A.M.1
Kim, J.K.2
Yakar, S.3
Dupont, J.4
Hernandez-Sanchez, C.5
Castle, A.L.6
Filmore, J.7
Shulman, G.I.8
Le Roith, D.9
-
23
-
-
0142026832
-
Potential roles of insulin and IGF-1 in Alzheimer's disease
-
Gasparini L., Xu H. Potential roles of insulin and IGF-1 in Alzheimer's disease. Trends Neurosci. 26:2003;404-406.
-
(2003)
Trends Neurosci.
, vol.26
, pp. 404-406
-
-
Gasparini, L.1
Xu, H.2
-
24
-
-
0035871641
-
Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling
-
Gasparini L., Gouras G.K., Wang R., Gross R.S., Beal M.F., Greengard P., Xu H. Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J. Neurosci. 21:2001;2561-2570.
-
(2001)
J. Neurosci.
, vol.21
, pp. 2561-2570
-
-
Gasparini, L.1
Gouras, G.K.2
Wang, R.3
Gross, R.S.4
Beal, M.F.5
Greengard, P.6
Xu, H.7
-
26
-
-
0031017561
-
Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels
-
Golden P.L., Maccagnan T.J., Pardridge W.M. Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels. J. Clin. Invest. 99:1997;14-18.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 14-18
-
-
Golden, P.L.1
MacCagnan, T.J.2
Pardridge, W.M.3
-
27
-
-
0035826833
-
Insulin-like growth factor I potentiates kainate receptors through a phosphatidylinositol 3-kinase dependent pathway
-
Gonzalez D.L.V., Buno W., Pons S., Garcia-Calderat M.S., Garcia-Galloway E., Torres-Aleman I. Insulin-like growth factor I potentiates kainate receptors through a phosphatidylinositol 3-kinase dependent pathway. NeuroReport. 12:2001;1293-1296.
-
(2001)
NeuroReport
, vol.12
, pp. 1293-1296
-
-
Gonzalez, D.L.V.1
Buno, W.2
Pons, S.3
Garcia-Calderat, M.S.4
Garcia-Galloway, E.5
Torres-Aleman, I.6
-
28
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I., Iqbal K., Tung Y.C., Quinlan M., Wisniewski H.M., Binder L.I. Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. U. S. A. 83:1986;4913-4917.
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
29
-
-
0030845325
-
Increased neural activity in transgenic mice with brain IGF-I overexpression: A [3H]2DG study
-
Gutierrez-Ospina G., Saum L., Calikoglu A.S., Diaz-Cintra S., Barrios F.A., D'Ercole A.J. Increased neural activity in transgenic mice with brain IGF-I overexpression: a [3H]2DG study. NeuroReport. 8:1997;2907-2911.
-
(1997)
NeuroReport
, vol.8
, pp. 2907-2911
-
-
Gutierrez-Ospina, G.1
Saum, L.2
Calikoglu, A.S.3
Diaz-Cintra, S.4
Barrios, F.A.5
D'Ercole, A.J.6
-
30
-
-
0026487365
-
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
-
Hanger D.P., Hughes K., Woodgett J.R., Brion J.P., Anderton B.H. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci. Lett. 147:1992;58-62.
-
(1992)
Neurosci. Lett.
, vol.147
, pp. 58-62
-
-
Hanger, D.P.1
Hughes, K.2
Woodgett, J.R.3
Brion, J.P.4
Anderton, B.H.5
-
32
-
-
0344672942
-
APP processing and synaptic function
-
Kamenetz F., Tomita T., Hsieh H., Seabrook G., Borchelt D., Iwatsubo T., Sisodia S., Malinow R. APP processing and synaptic function. Neuron. 37:2003;925-937.
-
(2003)
Neuron
, vol.37
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Hsieh, H.3
Seabrook, G.4
Borchelt, D.5
Iwatsubo, T.6
Sisodia, S.7
Malinow, R.8
-
33
-
-
0033162068
-
Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I
-
Kanzaki M., Zhang Y.Q., Mashima H., Li L., Shibata H., Kojima I. Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I. Nat. Cell Biol. 1:1999;165-170.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 165-170
-
-
Kanzaki, M.1
Zhang, Y.Q.2
Mashima, H.3
Li, L.4
Shibata, H.5
Kojima, I.6
-
34
-
-
0041419377
-
Acute in vivo elevation of insulin-like growth factor (IGF) binding protein-1 decreases plasma free IGF-I and muscle protein synthesis
-
Lang C.H., Vary T.C., Frost R.A. Acute in vivo elevation of insulin-like growth factor (IGF) binding protein-1 decreases plasma free IGF-I and muscle protein synthesis. Endocrinology. 144:2003;3922-3933.
-
(2003)
Endocrinology
, vol.144
, pp. 3922-3933
-
-
Lang, C.H.1
Vary, T.C.2
Frost, R.A.3
-
35
-
-
0027400362
-
Localization of insulin-like growth factor binding protein-2 messenger RNA during postnatal brain development: Correlation with insulin-like growth factors I and II
-
Lee W.H., Michels K.M., Bondy C.A. Localization of insulin-like growth factor binding protein-2 messenger RNA during postnatal brain development: correlation with insulin-like growth factors I and II. Neuroscience. 53:1993;251-265.
-
(1993)
Neuroscience
, vol.53
, pp. 251-265
-
-
Lee, W.H.1
Michels, K.M.2
Bondy, C.A.3
-
36
-
-
0036813726
-
Amyloid beta antagonizes insulin promoted secretion of the amyloid beta protein precursor
-
Ling X., Martins R.N., Racchi M., Craft S., Helmerhorst E. Amyloid beta antagonizes insulin promoted secretion of the amyloid beta protein precursor. J. Alzheimer's Dis. 4:2002;369-374.
-
(2002)
J. Alzheimer's Dis.
, vol.4
, pp. 369-374
-
-
Ling, X.1
Martins, R.N.2
Racchi, M.3
Craft, S.4
Helmerhorst, E.5
-
37
-
-
0345767139
-
Potentiation of quantal secretion by insulin-like growth factor-1 at developing motoneurons in Xenopus cell culture
-
Liou J.C., Tsai F.Z., Ho S.Y. Potentiation of quantal secretion by insulin-like growth factor-1 at developing motoneurons in Xenopus cell culture. J. Physiol. 553:2003;719-728.
-
(2003)
J. Physiol.
, vol.553
, pp. 719-728
-
-
Liou, J.C.1
Tsai, F.Z.2
Ho, S.Y.3
-
38
-
-
0033681557
-
Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
-
Man Y.H., Lin J.W., Ju W.H., Ahmadian G., Liu L., Becker L.E., Sheng M., Wang Y.T. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron. 25:2000;649-662.
-
(2000)
Neuron
, vol.25
, pp. 649-662
-
-
Man, Y.H.1
Lin, J.W.2
Ju, W.H.3
Ahmadian, G.4
Liu, L.5
Becker, L.E.6
Sheng, M.7
Wang, Y.T.8
-
39
-
-
0037198042
-
Brain evolution and lifespan regulation: Conservation of signal transduction pathways that regulate energy metabolism
-
Mattson M.P. Brain evolution and lifespan regulation: conservation of signal transduction pathways that regulate energy metabolism. Mech. Ageing Dev. 123:2002;947-953.
-
(2002)
Mech. Ageing Dev.
, vol.123
, pp. 947-953
-
-
Mattson, M.P.1
-
40
-
-
0031797783
-
Curly fiber and tangle-like inclusions in the ependyma and choroid plexus - A pathogenetic relationship with the cortical Alzheimer-type changes?
-
Miklossy J., Kraftsik R., Pillevuit O., Lepori D., Genton C., Bosman F.T. Curly fiber and tangle-like inclusions in the ependyma and choroid plexus - a pathogenetic relationship with the cortical Alzheimer-type changes? J. Neuropathol. Exp. Neurol. 57:1998;1202-1212.
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 1202-1212
-
-
Miklossy, J.1
Kraftsik, R.2
Pillevuit, O.3
Lepori, D.4
Genton, C.5
Bosman, F.T.6
-
41
-
-
0036776251
-
Association between the insulin resistance of puberty and the insulin-like growth factor-I/growth hormone axis
-
Moran A., Jacobs D.R. Jr., Steinberger J., Cohen P., Hong C.P., Prineas R., Sinaiko A.R. Association between the insulin resistance of puberty and the insulin-like growth factor-I/growth hormone axis. J. Clin. Endocrinol. Metab. 87:2002;4817-4820.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 4817-4820
-
-
Moran, A.1
Jacobs Jr., D.R.2
Steinberger, J.3
Cohen, P.4
Hong, C.P.5
Prineas, R.6
Sinaiko, A.R.7
-
42
-
-
0032712557
-
Decreased plasma insulin-like growth factor-I level in familial Alzheimer's disease patients carrying the Swedish APP 670/671 mutation
-
Mustafa A., Lannfelt L., Lilius L., Islam A., Winblad B., Adem A. Decreased plasma insulin-like growth factor-I level in familial Alzheimer's disease patients carrying the Swedish APP 670/671 mutation. Dement. Geriatr. Cogn. Disord. 10:1999;446-451.
-
(1999)
Dement. Geriatr. Cogn. Disord.
, vol.10
, pp. 446-451
-
-
Mustafa, A.1
Lannfelt, L.2
Lilius, L.3
Islam, A.4
Winblad, B.5
Adem, A.6
-
43
-
-
18344401228
-
Insulin-like growth factor I modifies electrophysiological properties of brainstem neurons
-
Nunez A., Carro E., Torres-Aleman I. Insulin-like growth factor I modifies electrophysiological properties of brainstem neurons. J. Neurophysiol. 89:2003;3008-3017.
-
(2003)
J. Neurophysiol.
, vol.89
, pp. 3008-3017
-
-
Nunez, A.1
Carro, E.2
Torres-Aleman, I.3
-
44
-
-
0036738463
-
IGF-I/IGF-binding protein-3 combination improves insulin resistance by GH-dependent and independent mechanisms
-
O'Connell T., Clemmons D.R. IGF-I/IGF-binding protein-3 combination improves insulin resistance by GH-dependent and independent mechanisms. J. Clin. Endocrinol. Metab. 87:2002;4356-4360.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 4356-4360
-
-
O'Connell, T.1
Clemmons, D.R.2
-
45
-
-
0036935830
-
Junctional complexes of the blood-brain barrier: Permeability changes in neuroinflammation
-
Petty M.A., Lo E.H. Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation. Prog. Neurobiol. 68:2002;311-323.
-
(2002)
Prog. Neurobiol.
, vol.68
, pp. 311-323
-
-
Petty, M.A.1
Lo, E.H.2
-
46
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
Phiel C.J., Wilson C.A., Lee V.M., Klein P.S. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature. 423:2003;435-439.
-
(2003)
Nature
, vol.423
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
Klein, P.S.4
-
47
-
-
0035201651
-
Patients with Alzheimer's disease display a pro-inflammatory phenotype
-
Remarque E.J., Bollen E.L., Weverling-Rijnsburger A.W., Laterveer J.C., Blauw G.J., Westendorp R.G. Patients with Alzheimer's disease display a pro-inflammatory phenotype. Prog. Neurobiol. 36:2001;171-176.
-
(2001)
Prog. Neurobiol.
, vol.36
, pp. 171-176
-
-
Remarque, E.J.1
Bollen, E.L.2
Weverling-Rijnsburger, A.W.3
Laterveer, J.C.4
Blauw, G.J.5
Westendorp, R.G.6
-
49
-
-
0035144307
-
Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways
-
Rui L., Aguirre V., Kim J.K., Shulman G.I., Lee A., Corbould A., Dunaif A., White M.F. Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways. J. Clin. Invest. 107:2001;181-189.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 181-189
-
-
Rui, L.1
Aguirre, V.2
Kim, J.K.3
Shulman, G.I.4
Lee, A.5
Corbould, A.6
Dunaif, A.7
White, M.F.8
-
50
-
-
0037134529
-
Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture
-
Sakai K., Lowman H.B., Clemmons D.R. Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture. J. Biol. Chem. 277:2002;13620-13627.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13620-13627
-
-
Sakai, K.1
Lowman, H.B.2
Clemmons, D.R.3
-
51
-
-
0037129721
-
Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: A prospective observational study
-
Sandhu M.S., Heald A.H., Gibson J.M., Cruickshank J.K., Dunger D.B., Wareham N.J. Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study. Lancet. 359:2002;1740-1745.
-
(2002)
Lancet
, vol.359
, pp. 1740-1745
-
-
Sandhu, M.S.1
Heald, A.H.2
Gibson, J.M.3
Cruickshank, J.K.4
Dunger, D.B.5
Wareham, N.J.6
-
52
-
-
0043127453
-
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
-
Schubert M., Brazil D.P., Burks D.J., Kushner J.A., Ye J., Flint C.L., Farhang-Fallah J., Dikkes P., Warot X.M., Rio C., Corfas G., White M.F. Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation. J. Neurosci. 23:2003;7084-7092.
-
(2003)
J. Neurosci.
, vol.23
, pp. 7084-7092
-
-
Schubert, M.1
Brazil, D.P.2
Burks, D.J.3
Kushner, J.A.4
Ye, J.5
Flint, C.L.6
Farhang-Fallah, J.7
Dikkes, P.8
Warot, X.M.9
Rio, C.10
Corfas, G.11
White, M.F.12
-
53
-
-
0026670206
-
Insulin in the brain: A hormonal regulator of energy balance
-
Schwartz M.W., Figlewicz D.P., Baskin D.G., Woods S.C., Porte D. Jr. Insulin in the brain: a hormonal regulator of energy balance. Endocr. Rev. 13:1992;387-414.
-
(1992)
Endocr. Rev.
, vol.13
, pp. 387-414
-
-
Schwartz, M.W.1
Figlewicz, D.P.2
Baskin, D.G.3
Woods, S.C.4
Porte Jr., D.5
-
54
-
-
0035950225
-
Clearing the brain's amyloid cobwebs
-
Selkoe D.J. Clearing the brain's amyloid cobwebs. Neuron. 32:2001;177-180.
-
(2001)
Neuron
, vol.32
, pp. 177-180
-
-
Selkoe, D.J.1
-
56
-
-
0033664955
-
Overproduction of IFN-gamma and TNF-alpha from natural killer (NK) cells is associated with abnormal NK reactivity and cognitive derangement in Alzheimer's disease
-
Solerte S.B., Cravello L., Ferrari E., Fioravanti M. Overproduction of IFN-gamma and TNF-alpha from natural killer (NK) cells is associated with abnormal NK reactivity and cognitive derangement in Alzheimer's disease. Ann. N. Y. Acad. Sci. 917:2000;331-340.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.917
, pp. 331-340
-
-
Solerte, S.B.1
Cravello, L.2
Ferrari, E.3
Fioravanti, M.4
-
57
-
-
0033948974
-
Choroid plexus in the central nervous system: Biology and physiopathology
-
Strazielle N., Ghersi-Egea J.F. Choroid plexus in the central nervous system: biology and physiopathology. J. Neuropathol. Exp. Neurol. 59:2000;561-574.
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 561-574
-
-
Strazielle, N.1
Ghersi-Egea, J.F.2
-
58
-
-
0027170501
-
Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type
-
Tham A., Nordberg A., Grissom F.E., Carlsson-Skwirut C., Viitanen M., Sara V.R. Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type. J. Neural Transm., Parkinson's Dis. Dement. Sect. 5:1993;165-176.
-
(1993)
J. Neural Transm., Parkinson's Dis. Dement. Sect.
, vol.5
, pp. 165-176
-
-
Tham, A.1
Nordberg, A.2
Grissom, F.E.3
Carlsson-Skwirut, C.4
Viitanen, M.5
Sara, V.R.6
-
59
-
-
1642379156
-
Role of insulin-like growth factor I signaling in neurodegenerative diseases
-
Trejo J.L., Carro E., Garcia-Galloway E., Torres-Aleman I. Role of insulin-like growth factor I signaling in neurodegenerative diseases. J. Mol. Med. 82:2003;156-162.
-
(2003)
J. Mol. Med.
, vol.82
, pp. 156-162
-
-
Trejo, J.L.1
Carro, E.2
Garcia-Galloway, E.3
Torres-Aleman, I.4
-
60
-
-
18244416706
-
Apolipoprotein E4 promotes the early deposition of Abeta42 and then Abeta40 in the elderly
-
Walker L.C., Pahnke J., Madauss M., Vogelgesang S., Pahnke A., Herbst E.W., Stausske D., Walther R., Kessler C., Warzok R.W. Apolipoprotein E4 promotes the early deposition of Abeta42 and then Abeta40 in the elderly. Acta Neuropathol. (Berl.). 100:2000;36-42.
-
(2000)
Acta Neuropathol. (Berl.)
, vol.100
, pp. 36-42
-
-
Walker, L.C.1
Pahnke, J.2
Madauss, M.3
Vogelgesang, S.4
Pahnke, A.5
Herbst, E.W.6
Stausske, D.7
Walther, R.8
Kessler, C.9
Warzok, R.W.10
-
61
-
-
0030800192
-
Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin
-
Wan Q., Xiong Z.G., Man H.Y., Ackerley C.A., Braunton J., Lu W.Y., Becker L.E., MacDonald J.F., Wang Y.T. Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin. Nature. 388:1997;686-690.
-
(1997)
Nature
, vol.388
, pp. 686-690
-
-
Wan, Q.1
Xiong, Z.G.2
Man, H.Y.3
Ackerley, C.A.4
Braunton, J.5
Lu, W.Y.6
Becker, L.E.7
MacDonald, J.F.8
Wang, Y.T.9
-
62
-
-
0037221379
-
The role of insulin resistance in the pathogenesis of Alzheimer's disease: Implications for treatment
-
Watson G.S., Craft S. The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment. CNS Drugs. 17:2003;27-45.
-
(2003)
CNS Drugs
, vol.17
, pp. 27-45
-
-
Watson, G.S.1
Craft, S.2
-
63
-
-
0038038865
-
Insulin increases CSF Abeta42 levels in normal older adults
-
Watson G.S., Peskind E.R., Asthana S., Purganan K., Wait C., Chapman D., Schwartz M.W., Plymate S., Craft S. Insulin increases CSF Abeta42 levels in normal older adults. Neurology. 60:2003;1899-1903.
-
(2003)
Neurology
, vol.60
, pp. 1899-1903
-
-
Watson, G.S.1
Peskind, E.R.2
Asthana, S.3
Purganan, K.4
Wait, C.5
Chapman, D.6
Schwartz, M.W.7
Plymate, S.8
Craft, S.9
-
64
-
-
0036450037
-
Cerebrovascular disease is a major factor in the failure of elimination of Abeta from the aging human brain: Implications for therapy of Alzheimer's disease
-
Weller R.O., Yow H.Y., Preston S.D., Mazanti I., Nicoll J.A. Cerebrovascular disease is a major factor in the failure of elimination of Abeta from the aging human brain: implications for therapy of Alzheimer's disease. Ann. N. Y. Acad. Sci. 977:2002;162-168.
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.977
, pp. 162-168
-
-
Weller, R.O.1
Yow, H.Y.2
Preston, S.D.3
Mazanti, I.4
Nicoll, J.A.5
-
65
-
-
0037460835
-
Free insulin-like growth factor (IGF)-I and IGF binding proteins 2, 5, and 6 in spinal motor neurons in amyotrophic lateral sclerosis
-
Wilczak N., de Vos R.A., De Keyser J. Free insulin-like growth factor (IGF)-I and IGF binding proteins 2, 5, and 6 in spinal motor neurons in amyotrophic lateral sclerosis. Lancet. 361:2003;1007-1011.
-
(2003)
Lancet
, vol.361
, pp. 1007-1011
-
-
Wilczak, N.1
De Vos, R.A.2
De Keyser, J.3
-
66
-
-
0030940710
-
Acute exercise attenuates age-associated resistance to insulin-like growth factor I
-
Willis P.E., Chadan S., Baracos V., Parkhouse W.S. Acute exercise attenuates age-associated resistance to insulin-like growth factor I. Am. J. Physiol. 272:1997;E397-E404.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Willis, P.E.1
Chadan, S.2
Baracos, V.3
Parkhouse, W.S.4
-
67
-
-
18744438248
-
Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor
-
Xie L., Helmerhorst E., Taddei K., Plewright B., Van Bronswijk W., Martins R. Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor. J. Neurosci. 22:2002;RC221.
-
(2002)
J. Neurosci.
, vol.22
, pp. 221
-
-
Xie, L.1
Helmerhorst, E.2
Taddei, K.3
Plewright, B.4
Van Bronswijk, W.5
Martins, R.6
-
68
-
-
0035033682
-
Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity
-
Yakar S., Liu J.L., Fernandez A.M., Wu Y., Schally A.V., Frystyk J., Chernausek S.D., Mejia W., Le Roith D. Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity. Diabetes. 50:2001;1110-1118.
-
(2001)
Diabetes
, vol.50
, pp. 1110-1118
-
-
Yakar, S.1
Liu, J.L.2
Fernandez, A.M.3
Wu, Y.4
Schally, A.V.5
Frystyk, J.6
Chernausek, S.D.7
Mejia, W.8
Le Roith, D.9
|