A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis

Volumn 1, Issue 3, 2000, Pages 201-206

  Ochs, Günter ^a   Penn, Richard D ^b   York, Michelle ^b   Giess, Ralf ^a   Beck, Marcus ^a   Tonn, Jörg ^a   Haigh, Jeremy ^c   Malta, E ^c   Traub, Michael ^c   Sendtner, Michael ^a   Toyka, Klaus V ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c AMGEN LTD   (United Kingdom)

Author keywords

Amyotrophic Lateral Sclerosis Brain DERIVED Neurotrophic Factor Intrathecal Delivery

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; R METHUBDNF PROTEIN, RECOMBINANT; R-METHUBDNF PROTEIN, RECOMBINANT; RECOMBINANT PROTEIN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HUMAN; INTRASPINAL DRUG ADMINISTRATION; MIDDLE AGED; ODOR; PARESTHESIA; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; SLEEP DISORDER; TASTE;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DOUBLE-BLIND METHOD; HUMANS; INJECTIONS, SPINAL; MIDDLE AGED; PARESTHESIA; RECOMBINANT PROTEINS; SLEEP DISORDERS; SMELL; TASTE;

EID: 0034208461     PISSN: 17482968     EISSN: 1471180X     Source Type: Journal    
DOI: 10.1080/14660820050515197     Document Type: Article

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