Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death

Journal of Neuroscience

Volumn 26, Issue 20, 2006, Pages 5288-5300

  Massa, Stephen M ^a,b   Xie, Youmei ^c   Yang, Tao ^c   Harrington, Anthony W ^d   Mi, Lyang Kim ^d   Sung, Ok Yoon ^d   Kraemer, Rosemary ^e   Moore, Laura A ^c   Hempstead, Barbara L ^e   Longo, Frank M ^c,f  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f STANFORD UNIVERSITY   (United States)

Author keywords

Brain derived neurotrophic factor; Hippocampal neurons; Nerve growth factor; Neurotrophin receptor; Oligodendrocytes; p75; Small molecules

Indexed keywords

NEUROTROPHIN; NEUROTROPHIN RECEPTOR; PROTEIN P75; RECOMBINANT NERVE GROWTH FACTOR; LIGAND; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; NEUROPROTECTIVE AGENT; PRO NERVE GROWTH FACTOR, MOUSE; PRO-NERVE GROWTH FACTOR, MOUSE; PROTEIN PRECURSOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL DEATH; CELL SCREENING; CELL SURVIVAL; COMPUTER MODEL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOPRECIPITATION; IN VITRO STUDY; MOLECULAR LIBRARY; MOUSE; NONHUMAN; PHARMACOPHORE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; RAT; ANIMAL; CELL STRAIN; CELL STRAIN 3T3; CHEMICAL STRUCTURE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; DRUG SCREENING; HIPPOCAMPUS; METABOLISM; METHODOLOGY; MOLECULAR WEIGHT; NERVE CELL; NEWBORN; OLIGODENDROGLIA; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; SYNTHESIS;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL SURVIVAL; DRUG EVALUATION, PRECLINICAL; HIPPOCAMPUS; LIGANDS; MICE; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; NEURONS; NEUROPROTECTIVE AGENTS; NIH 3T3 CELLS; OLIGODENDROGLIA; PC12 CELLS; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTOR, NERVE GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 33744994565     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3547-05.2006     Document Type: Article

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