-
1
-
-
0019822988
-
Thresholds in cerebral ischaemia - The ischemic penumbra
-
Astrup J, Siesjö BK, Symon L: Thresholds in cerebral ischaemia - The ischemic penumbra. Stroke 1981;12:723-725.
-
(1981)
Stroke
, vol.12
, pp. 723-725
-
-
Astrup, J.1
Siesjö, B.K.2
Symon, L.3
-
2
-
-
0020567603
-
Blood flow and vascular reactivity in collaterally perfused brain tissue: Evidence of an ischemic penumbra in patients with acute stroke
-
Olsen TS, Larsen B, Herning M, Skriver EB, Lassen NA: Blood flow and vascular reactivity in collaterally perfused brain tissue: Evidence of an ischemic penumbra in patients with acute stroke. Stroke 1983;14:332-341.
-
(1983)
Stroke
, vol.14
, pp. 332-341
-
-
Olsen, T.S.1
Larsen, B.2
Herning, M.3
Skriver, E.B.4
Lassen, N.A.5
-
3
-
-
0025114628
-
Randomised, double-blind, placebo-controlled trial of nimodipine in acute stroke
-
Trust Study Group: Randomised, double-blind, placebo-controlled trial of nimodipine in acute stroke. Lancet 1990;336:1205-1209.
-
(1990)
Lancet
, vol.336
, pp. 1205-1209
-
-
-
4
-
-
0026544260
-
Clinical trial of nimodipine in acute ischemic stroke
-
The American Nimodipine Study Group: Clinical trial of nimodipine in acute ischemic stroke. Stroke 1992;23:3-8.
-
(1992)
Stroke
, vol.23
, pp. 3-8
-
-
-
6
-
-
0001694755
-
The Intravenous Nimodipine West European Trial (INWEST) of nimodipine in the treatment of acute ischemic stroke
-
Wahlgren NG, MacMahon DG, for the IN-WEST Study Group: The Intravenous Nimodipine West European Trial (INWEST) of nimodipine in the treatment of acute ischemic stroke. Cerebrovasc Dis 1994;4:204-210.
-
(1994)
Cerebrovasc Dis
, vol.4
, pp. 204-210
-
-
Wahlgren, N.G.1
MacMahon, D.G.2
-
7
-
-
0031803008
-
Effect of nimodipine on memory after cerebral infarction
-
Sze KH, Sim TC, Wong E, Cheng S, Woo J: Effect of nimodipine on memory after cerebral infarction. Acta Neurol Scand 1998;97:386-392.
-
(1998)
Acta Neurol Scand
, vol.97
, pp. 386-392
-
-
Sze, K.H.1
Sim, T.C.2
Wong, E.3
Cheng, S.4
Woo, J.5
-
8
-
-
20244370977
-
Nimodipine in acute ischemic stroke: A double-blind controlled study
-
Paci A, Ottaviano P, Trenta A, Iannone G, De Santis L, Lancia G, Moschini E, Carosi M, Amigoni S, Caresia L: Nimodipine in acute ischemic stroke: A double-blind controlled study. Acta Neurol Scand 1989;80:282-286.
-
(1989)
Acta Neurol Scand
, vol.80
, pp. 282-286
-
-
Paci, A.1
Ottaviano, P.2
Trenta, A.3
Iannone, G.4
De Santis, L.5
Lancia, G.6
Moschini, E.7
Carosi, M.8
Amigoni, S.9
Caresia, L.10
-
9
-
-
0000404698
-
The Canwin Study Group: Intravenous nimodipine in acute ischemic stroke
-
Norris JW, LeBrun LH, Anderson BA: The Canwin Study Group: Intravenous nimodipine in acute ischemic stroke. Cerebrovasc Dis 1994;4:194-196.
-
(1994)
Cerebrovasc Dis
, vol.4
, pp. 194-196
-
-
Norris, J.W.1
LeBrun, L.H.2
Anderson, B.A.3
-
10
-
-
0031794687
-
A randomized double-blind controlled study of nimodipine in acute cerebral ischemic stroke
-
Nag D, Garg RK, Varma M: A randomized double-blind controlled study of nimodipine in acute cerebral ischemic stroke. Indian J Physiol Pharmacol 1998;42:555-558.
-
(1998)
Indian J Physiol Pharmacol
, vol.42
, pp. 555-558
-
-
Nag, D.1
Garg, R.K.2
Varma, M.3
-
11
-
-
0348083499
-
Placebo-controlled trial of nimodipine in the treatment of acute ischemic cerebral infarction
-
Martinez-Vila E, Guillen F, Villanueva JA, Matias-Guiu J, Bigorra J, Gil P, Carbonell A, Martinez-Lage JM: Placebo-controlled trial of nimodipine in the treatment of acute ischemic cerebral infarction. Angiology 1990;41(11, pt 2):1010-1016.
-
(1990)
Angiology
, vol.41
, Issue.11 PART 2
, pp. 1010-1016
-
-
Martinez-Vila, E.1
Guillen, F.2
Villanueva, J.A.3
Matias-Guiu, J.4
Bigorra, J.5
Gil, P.6
Carbonell, A.7
Martinez-Lage, J.M.8
-
12
-
-
0028243698
-
A randomized, double-blind, placebo-controlled trial of nimodipine in acute ischemic hemispheric stroke
-
Kaste M, Fogelholm R, Erila T, Palomaki H, Murros K, Rissanen A, Sarna S: A randomized, double-blind, placebo-controlled trial of nimodipine in acute ischemic hemispheric stroke. Stroke 1994;25:1348-1353.
-
(1994)
Stroke
, vol.25
, pp. 1348-1353
-
-
Kaste, M.1
Fogelholm, R.2
Erila, T.3
Palomaki, H.4
Murros, K.5
Rissanen, A.6
Sarna, S.7
-
13
-
-
0033025787
-
Nimodipine and perfusion changes after stroke
-
Infeld B, Davis SM, Donnan GA, Yasaka M, Lichtenstein M, Mitchell PJ, Fitt GJ: Nimodipine and perfusion changes after stroke. Stroke 1999;30:1417-1423.
-
(1999)
Stroke
, vol.30
, pp. 1417-1423
-
-
Infeld, B.1
Davis, S.M.2
Donnan, G.A.3
Yasaka, M.4
Lichtenstein, M.5
Mitchell, P.J.6
Fitt, G.J.7
-
14
-
-
0035134255
-
Very Early Nimodipine Use in Stroke (VENUS): A randomized, double-blind, placebo-controlled trial
-
Horn J, de Haan RJ, Vermeulen M, Limburg M: Very Early Nimodipine Use in Stroke (VENUS): A randomized, double-blind, placebo-controlled trial. Stroke 2001;32:461-465.
-
(2001)
Stroke
, vol.32
, pp. 461-465
-
-
Horn, J.1
De Haan, R.J.2
Vermeulen, M.3
Limburg, M.4
-
15
-
-
0025189748
-
Effect of nimodipine on regional cerebral glucose metabolism in patients with acute ischemic stroke as measured by positron emission tomography
-
Heiss WD, Holthoff V, Pawlik G, Neveling M: Effect of nimodipine on regional cerebral glucose metabolism in patients with acute ischemic stroke as measured by positron emission tomography. J Cereb Blood Flow Metab 1990;10:127-132.
-
(1990)
J Cereb Blood Flow Metab
, vol.10
, pp. 127-132
-
-
Heiss, W.D.1
Holthoff, V.2
Pawlik, G.3
Neveling, M.4
-
17
-
-
0021257790
-
The effects of nimodipine on the clinical course of patients with acute ischemic stroke
-
Gelmers HJ: The effects of nimodipine on the clinical course of patients with acute ischemic stroke. Acta Neurol Scand 1984;69:232-239.
-
(1984)
Acta Neurol Scand
, vol.69
, pp. 232-239
-
-
Gelmers, H.J.1
-
18
-
-
84939677173
-
Meta-analysis of oral nimodipine trials in acute ischemic stroke
-
Mohr JP, Orgogozo JM, Harrison MJG, Hennerici M, Wahlgren NG, Gelmers JH, Martinez-Vila E, Dycka J, Tettenborn D: Meta-analysis of oral nimodipine trials in acute ischemic stroke. Cerebrovasc Dis 1994;4:197-203.
-
(1994)
Cerebrovasc Dis
, vol.4
, pp. 197-203
-
-
Mohr, J.P.1
Orgogozo, J.M.2
Harrison, M.J.G.3
Hennerici, M.4
Wahlgren, N.G.5
Gelmers, J.H.6
Martinez-Vila, E.7
Dycka, J.8
Tettenborn, D.9
-
19
-
-
0343963044
-
Effect of intravenous nimodipine on blood pressure and outcome after acute stroke
-
Ahmed N, Nasman P, Wahlgren NG: Effect of intravenous nimodipine on blood pressure and outcome after acute stroke. Stroke 2000;31:1250-1255.
-
(2000)
Stroke
, vol.31
, pp. 1250-1255
-
-
Ahmed, N.1
Nasman, P.2
Wahlgren, N.G.3
-
20
-
-
0025736192
-
Early treatment of ischemic stroke with a calcium antagonist
-
Rosenbaum D, Zabramski J, Frey J, Yatsu F, Marler J, Spetzler R, Grotta J: Early treatment of ischemic stroke with a calcium antagonist. Stroke 1991;22:437-441.
-
(1991)
Stroke
, vol.22
, pp. 437-441
-
-
Rosenbaum, D.1
Zabramski, J.2
Frey, J.3
Yatsu, F.4
Marler, J.5
Spetzler, R.6
Grotta, J.7
-
21
-
-
0025342440
-
Flunarizine in acute ischemic stroke: A pilot study
-
Limburg M, Hijdra A: Flunarizine in acute ischemic stroke: A pilot study. Eur Neurol 1990;30:121-122.
-
(1990)
Eur Neurol
, vol.30
, pp. 121-122
-
-
Limburg, M.1
Hijdra, A.2
-
22
-
-
0030057032
-
Flunarizine in stroke treatment (FIST): A double-blind, placebo-controlled trial in Scandinavia and the Netherlands
-
Franke CL, Palm R, Dalby M, Schoonderwaldt HC, Hantson L, Eriksson B, Lang-Jenssen L, Smakman J: Flunarizine in stroke treatment (FIST): A double-blind, placebo-controlled trial in Scandinavia and the Netherlands. Acta Neurol Scand 1996;93:56-60.
-
(1996)
Acta Neurol Scand
, vol.93
, pp. 56-60
-
-
Franke, C.L.1
Palm, R.2
Dalby, M.3
Schoonderwaldt, H.C.4
Hantson, L.5
Eriksson, B.6
Lang-Jenssen, L.7
Smakman, J.8
-
23
-
-
0025048712
-
Isradipine in patients with acute ischaemic cerebral infarction: An overview of the ASCLEPIOS programme
-
Azcona A, Lataste X: Isradipine in patients with acute ischaemic cerebral infarction: An overview of the ASCLEPIOS programme. Drugs 1990;40(suppl 2):52-57.
-
(1990)
Drugs
, vol.40
, Issue.2 SUPPL.
, pp. 52-57
-
-
Azcona, A.1
Lataste, X.2
-
24
-
-
0024320191
-
A double-blind, randomized trial of PY108-068 in acute ischemic cerebral infarction
-
Oczkowski WJ, Hachinski VC, Bogousslavsky J, Barnett HJ, Carruthers SG: A double-blind, randomized trial of PY108-068 in acute ischemic cerebral infarction. Stroke 1989;20:604-608.
-
(1989)
Stroke
, vol.20
, pp. 604-608
-
-
Oczkowski, W.J.1
Hachinski, V.C.2
Bogousslavsky, J.3
Barnett, H.J.4
Carruthers, S.G.5
-
25
-
-
84921431308
-
Calcium antagonists for acute ischaemic stroke
-
CD001928
-
Horn J, Limburg M: Calcium antagonists for acute ischaemic stroke. Cochrane Database Syst Rev 2000;2:CD001928.
-
(2000)
Cochrane Database Syst Rev
, vol.2
-
-
Horn, J.1
Limburg, M.2
-
26
-
-
0031963836
-
Ebselen in acute ischemic stroke: A placebo-controlled, double-blind clinical trial
-
Ebselen Study Group
-
Yamaguchi T, Sano K, Takakura K, Saito I, Shinohara Y, Asano T, Yasuhara H: Ebselen in acute ischemic stroke: A placebo-controlled, double-blind clinical trial. Ebselen Study Group. Stroke 1998;29:12-17.
-
(1998)
Stroke
, vol.29
, pp. 12-17
-
-
Yamaguchi, T.1
Sano, K.2
Takakura, K.3
Saito, I.4
Shinohara, Y.5
Asano, T.6
Yasuhara, H.7
-
27
-
-
0033042957
-
Ebselen in acute middle cerebral artery occlusion: A placebo-controlled, double-blind clinical trial
-
Ogawa A, Yoshimoto T, Kikuchi H, Sano K, Saito I, Yamaguchi T, Yasuhara H: Ebselen in acute middle cerebral artery occlusion: A placebo-controlled, double-blind clinical trial. Cerebrovasc Dis 1999;9:112-118.
-
(1999)
Cerebrovasc Dis
, vol.9
, pp. 112-118
-
-
Ogawa, A.1
Yoshimoto, T.2
Kikuchi, H.3
Sano, K.4
Saito, I.5
Yamaguchi, T.6
Yasuhara, H.7
-
28
-
-
85069118634
-
-
The Internet Stroke Center. Washington University School of Medicine
-
The Internet Stroke Center. Washington University School of Medicine. URL: http://www.strokecenter.org/, 2002.
-
(2002)
-
-
-
29
-
-
0043204506
-
A randomized trial of tirilazad mesylate in patients with acute stroke (RANTTAS)
-
The RANTTAS Investigators: A randomized trial of tirilazad mesylate in patients with acute stroke (RANTTAS). Stroke 1996;27:1453-1458.
-
(1996)
Stroke
, vol.27
, pp. 1453-1458
-
-
-
30
-
-
0031781078
-
High-dose tirilazad for acute stroke (RANTTAS II)
-
RANTTAS II Investigators
-
Haley EC Jr: High-dose tirilazad for acute stroke (RANTTAS II). RANTTAS II Investigators. Stroke 1998;29:1256-1257.
-
(1998)
Stroke
, vol.29
, pp. 1256-1257
-
-
Haley Jr., E.C.1
-
32
-
-
0034745231
-
Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke
-
Lees KR, Sharma AK, Barer D, Ford GA, Kostulas V, Cheng YF, Odergren T: Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke. Stroke 2001;32:675-680.
-
(2001)
Stroke
, vol.32
, pp. 675-680
-
-
Lees, K.R.1
Sharma, A.K.2
Barer, D.3
Ford, G.A.4
Kostulas, V.5
Cheng, Y.F.6
Odergren, T.7
-
33
-
-
0032953495
-
Clomethiazole acute stroke study (CLASS): Results of a randomized, controlled trial of clomethiazole versus placebo in 1,360 acute stroke patients
-
Wahlgren NG, Ranasinha KW, Rosolacci T, Franke CL, van Erven PM, Ashwood T, Claesson L: Clomethiazole acute stroke study (CLASS): Results of a randomized, controlled trial of clomethiazole versus placebo in 1,360 acute stroke patients. Stroke 1999;30:21-28.
-
(1999)
Stroke
, vol.30
, pp. 21-28
-
-
Wahlgren, N.G.1
Ranasinha, K.W.2
Rosolacci, T.3
Franke, C.L.4
Van Erven, P.M.5
Ashwood, T.6
Claesson, L.7
-
34
-
-
0034235666
-
The clomethiazole acute stroke study (CLASS): Safety results in 1,356 patients with hemispheric stroke
-
Wahlgren NG, Matias-Guiu J, Lainez JM, Veloso F, Ranasinha K, Grossman E, Ashwood T: The clomethiazole acute stroke study (CLASS): Safety results in 1,356 patients with hemispheric stroke. J Stroke Cerebrovasc Dis 2000;9:158-165.
-
(2000)
J Stroke Cerebrovasc Dis
, vol.9
, pp. 158-165
-
-
Wahlgren, N.G.1
Matias-Guiu, J.2
Lainez, J.M.3
Veloso, F.4
Ranasinha, K.5
Grossman, E.6
Ashwood, T.7
-
35
-
-
0000251781
-
The Clomethiazole Acute Stroke Study (CLASS): Efficacy results in 545 patients classified as total anterior circulation syndrome (TACS)
-
Wahlgren NG, Bornhov S, Bornhov S, Sharma A, Cederin B, Rosolacci T, Ashwood T, Claesson L, for the CLASS study group: The Clomethiazole Acute Stroke Study (CLASS): Efficacy results in 545 patients classified as total anterior circulation syndrome (TACS). J Stroke Cerebrovasc Dis 1999;8:231-239.
-
(1999)
J Stroke Cerebrovasc Dis
, vol.8
, pp. 231-239
-
-
Wahlgren, N.G.1
Bornhov, S.2
Bornhov, S.3
Sharma, A.4
Cederin, B.5
Rosolacci, T.6
Ashwood, T.7
Claesson, L.8
-
36
-
-
0033971797
-
Results in 95 hemorrhagic stroke patients included in CLASS, a controlled trial of clomethiazole versus placebo in acute stroke patients
-
Wahlgren NG, Diez-Tejedor E, Teitelbaum J, Arboix A, Leys D, Ashwood T, Grossman E: Results in 95 hemorrhagic stroke patients included in CLASS, a controlled trial of clomethiazole versus placebo in acute stroke patients. Stroke 2000;31:82-85.
-
(2000)
Stroke
, vol.31
, pp. 82-85
-
-
Wahlgren, N.G.1
Diez-Tejedor, E.2
Teitelbaum, J.3
Arboix, A.4
Leys, D.5
Ashwood, T.6
Grossman, E.7
-
37
-
-
18244392468
-
Clomethiazole Acute Stroke Study in ischemic stroke (CLASS-I): Final results
-
Lyden P, Shuaib A, Ng K, Levin K, Atkinson RP, Rajput A, Wechsler L, Ashwood T, Claesson L, Odergren T, Salazar-Grueso E: Clomethiazole Acute Stroke Study in ischemic stroke (CLASS-I): Final results. Stroke 2002;33:122-128.
-
(2002)
Stroke
, vol.33
, pp. 122-128
-
-
Lyden, P.1
Shuaib, A.2
Ng, K.3
Levin, K.4
Atkinson, R.P.5
Rajput, A.6
Wechsler, L.7
Ashwood, T.8
Claesson, L.9
Odergren, T.10
Salazar-Grueso, E.11
-
38
-
-
85069108635
-
Early GABA-ergic Activation Study in Stroke (EGASIS)
-
Early GABA-ergic Activation Study in Stroke (EGASIS). Stroke 2002;33:646-655.
-
(2002)
Stroke
, vol.33
, pp. 646-655
-
-
-
39
-
-
85069108371
-
AMPA Receptor Antagonist Treatment in Ischemic Stroke Trial, YM872 + Alteplase
-
ARTIST +: AMPA Receptor Antagonist Treatment in Ischemic Stroke Trial, YM872 + Alteplase. Ongoing Clinical Trials Session, 27th Int Stroke Conf, URL: http://stroke.ahajournals.org/, 2002.
-
(2002)
Ongoing Clinical Trials Session, 27th Int Stroke Conf
-
-
-
40
-
-
85069098192
-
AMPA Receptor Antagonist Treatment in Ischemic Stroke Trial-MRI
-
ARTIST MRI: AMPA Receptor Antagonist Treatment in Ischemic Stroke Trial-MRI. Ongoing Clinical Trials Session, 27th Int Stroke Conf, URL: http://stroke.ahajournals.org/, 2002.
-
(2002)
Ongoing Clinical Trials Session, 27th Int Stroke Conf
-
-
-
41
-
-
0028921447
-
Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke: Results of a phase IIa randomized trial
-
Grotta J, Clark W, Coull B, Pettigrew LC, Mackay B, Goldstein LB, Meissner I, Murphy D, LaRue L: Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke: Results of a phase IIa randomized trial. Stroke 1995;26:602-605.
-
(1995)
Stroke
, vol.26
, pp. 602-605
-
-
Grotta, J.1
Clark, W.2
Coull, B.3
Pettigrew, L.C.4
Mackay, B.5
Goldstein, L.B.6
Meissner, I.7
Murphy, D.8
LaRue, L.9
-
42
-
-
0033951941
-
Selfotel in acute ischemic stroke: Possible neurotoxic effects of an NMDA antagonist
-
Davis SM, Lees KR, Albers GW, Diener HC, Markabi S, Karlsson G, Norris J: Selfotel in acute ischemic stroke: Possible neurotoxic effects of an NMDA antagonist. Stroke 2000;31:347-354.
-
(2000)
Stroke
, vol.31
, pp. 347-354
-
-
Davis, S.M.1
Lees, K.R.2
Albers, G.W.3
Diener, H.C.4
Markabi, S.5
Karlsson, G.6
Norris, J.7
-
43
-
-
0035814418
-
Aptiganel hydrochloride in acute ischemic stroke: A randomized controlled trial
-
Albers GW, Goldstein LB, Hall D, Lesko LM: Aptiganel hydrochloride in acute ischemic stroke: A randomized controlled trial. JAMA 2001;286:2673-2682.
-
(2001)
JAMA
, vol.286
, pp. 2673-2682
-
-
Albers, G.W.1
Goldstein, L.B.2
Hall, D.3
Lesko, L.M.4
-
44
-
-
0033387727
-
An open-label study of CP-101,606 in subjects with a severe traumatic head injury or spontaneous intracerebral haemorrhage
-
Bullock MR, Merchant RE, Carmack CA, Doppenberg E, Shah AK, Wilner KD, Ko G, Williams SA: An open-label study of CP-101,606 in subjects with a severe traumatic head injury or spontaneous intracerebral haemorrhage. Ann NY Acad Sci 1999;890:51-58.
-
(1999)
Ann NY Acad Sci
, vol.890
, pp. 51-58
-
-
Bullock, M.R.1
Merchant, R.E.2
Carmack, C.A.3
Doppenberg, E.4
Shah, A.K.5
Wilner, K.D.6
Ko, G.7
Williams, S.A.8
-
45
-
-
0028870990
-
Safety, tolerability, and pharmacokinetics of the N-methyl-D-aspartate antagonist dextrorphan in patients with acute stroke
-
Dextrorphan Study Group
-
Albers GW, Atkinson RP, Kelley RE, Rosenbaum DM: Safety, tolerability, and pharmacokinetics of the N-methyl-D-aspartate antagonist dextrorphan in patients with acute stroke. Dextrorphan Study Group. Stroke 1995;26:254-258.
-
(1995)
Stroke
, vol.26
, pp. 254-258
-
-
Albers, G.W.1
Atkinson, R.P.2
Kelley, R.E.3
Rosenbaum, D.M.4
-
46
-
-
0029067191
-
A randomized, double-blind, placebo-controlled pilot trial of intravenous magnesium sulfate in acute stroke
-
Muir KW, Lees KR: A randomized, double-blind, placebo-controlled pilot trial of intravenous magnesium sulfate in acute stroke. Stroke 1995;26:1183-1188.
-
(1995)
Stroke
, vol.26
, pp. 1183-1188
-
-
Muir, K.W.1
Lees, K.R.2
-
47
-
-
0037070516
-
News about neuroprotectants for the treatment of stroke
-
Mitka M: News about neuroprotectants for the treatment of stroke. JAMA 2002;287:1253-1254.
-
(2002)
JAMA
, vol.287
, pp. 1253-1254
-
-
Mitka, M.1
-
48
-
-
85069116393
-
Intravenous Magnesium Efficacy in Stroke Trial (IMAGES)
-
Intravenous Magnesium Efficacy in Stroke Trial (IMAGES). Stroke 2002;33:646-655.
-
(2002)
Stroke
, vol.33
, pp. 646-655
-
-
-
49
-
-
0032875690
-
Remacemide hydrochloride: A double-blind, placebo-controlled, safety and tolerability study in patients with acute ischemic stroke
-
Dyker AG, Lees KR: Remacemide hydrochloride: A double-blind, placebo-controlled, safety and tolerability study in patients with acute ischemic stroke. Stroke 1999;30:1796-1801.
-
(1999)
Stroke
, vol.30
, pp. 1796-1801
-
-
Dyker, A.G.1
Lees, K.R.2
-
50
-
-
0032967750
-
Dose escalation study of the NMDA glycine-site antagonist licostinel in acute ischemic stroke
-
Albers GW, Clark WM, Atkinson RP, Madden K, Data JL, Whitehouse MJ: Dose escalation study of the NMDA glycine-site antagonist licostinel in acute ischemic stroke. Stroke 1999;30:508-513.
-
(1999)
Stroke
, vol.30
, pp. 508-513
-
-
Albers, G.W.1
Clark, W.M.2
Atkinson, R.P.3
Madden, K.4
Data, J.L.5
Whitehouse, M.J.6
-
51
-
-
0035804844
-
Glycine antagonist in neuroprotection for patients with acute stroke - GAIN Americas: A randomized controlled trial
-
Sacco RL, DeRosa JT, Haley EC Jr, Levin B, Ordronneau P, Phillips SJ, Rundek T, Snipes RG, Thompson JL: Glycine antagonist in neuroprotection for patients with acute stroke - GAIN Americas: A randomized controlled trial. JAMA 2001;285:1719-1728.
-
(2001)
JAMA
, vol.285
, pp. 1719-1728
-
-
Sacco, R.L.1
DeRosa, J.T.2
Haley Jr., E.C.3
Levin, B.4
Ordronneau, P.5
Phillips, S.J.6
Rundek, T.7
Snipes, R.G.8
Thompson, J.L.9
-
52
-
-
0034600485
-
Glycine antagonist (gavestinel) in neuroprotection (GAIN International) in patients with acute stroke: A randomised controlled trial
-
GAIN International Investigators
-
Lees KR, Asplund K, Carolei A, Davis SM, Diener HC, Kaste M, Orgogozo JM, Whitehead J: Glycine antagonist (gavestinel) in neuroprotection (GAIN International) in patients with acute stroke: A randomised controlled trial. GAIN International Investigators. Lancet 2000;355:1949-1954.
-
(2000)
Lancet
, vol.355
, pp. 1949-1954
-
-
Lees, K.R.1
Asplund, K.2
Carolei, A.3
Davis, S.M.4
Diener, H.C.5
Kaste, M.6
Orgogozo, J.M.7
Whitehead, J.8
-
53
-
-
0030666876
-
Cerestat and other NMDA antagonists in ischemic stroke
-
Lees KR: Cerestat and other NMDA antagonists in ischemic stroke. Neurology 1997;49(suppl 4):S66-S69.
-
(1997)
Neurology
, vol.49
, Issue.4 SUPPL.
-
-
Lees, K.R.1
-
54
-
-
0032892598
-
Potential usefulness of basic fibroblast growth factor as a treatment for stroke
-
Ay H, Ay I, Koroshetz WJ, Finklestein SP: Potential usefulness of basic fibroblast growth factor as a treatment for stroke. Cerebrovasc Dis 1999;9:131-135.
-
(1999)
Cerebrovasc Dis
, vol.9
, pp. 131-135
-
-
Ay, H.1
Ay, I.2
Koroshetz, W.J.3
Finklestein, S.P.4
-
55
-
-
0035940577
-
Use of anti-ICAM-1 therapy in ischemic stroke: Results of the Enlimomab Acute Stroke Trial
-
Use of anti-ICAM-1 therapy in ischemic stroke: Results of the Enlimomab Acute Stroke Trial. Neurology 2001;57:1428-1434.
-
(2001)
Neurology
, vol.57
, pp. 1428-1434
-
-
-
56
-
-
0031438509
-
Lubeluzole treatment of acute ischemic stroke: The US and Canadian Lubeluzole Ischemic Stroke Study Group
-
Grotta J: Lubeluzole treatment of acute ischemic stroke: The US and Canadian Lubeluzole Ischemic Stroke Study Group. Stroke 1997;28:2338-2346.
-
(1997)
Stroke
, vol.28
, pp. 2338-2346
-
-
Grotta, J.1
-
57
-
-
0033766740
-
Lubeluzole in acute ischemic stroke treatment: A double-blind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubeluzole with placebo
-
Diener HC, Cortens M, Ford G, Grotta J, Hacke W, Kaste M, Koudstaal PJ, Wessel T: Lubeluzole in acute ischemic stroke treatment: A double-blind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubeluzole with placebo. Stroke 2000;31:2543-2551.
-
(2000)
Stroke
, vol.31
, pp. 2543-2551
-
-
Diener, H.C.1
Cortens, M.2
Ford, G.3
Grotta, J.4
Hacke, W.5
Kaste, M.6
Koudstaal, P.J.7
Wessel, T.8
-
58
-
-
0001223098
-
Cervene in acute ischemic stroke: Results of a double-blind, placebo-controlled, dose-comparison study
-
Wayne C, William E, Edward O, Eric R: Cervene in acute ischemic stroke: Results of a double-blind, placebo-controlled, dose-comparison study. J Stroke Cerebrovasc Dis 1999;8:224-230.
-
(1999)
J Stroke Cerebrovasc Dis
, vol.8
, pp. 224-230
-
-
Wayne, C.1
William, E.2
Edward, O.3
Eric, R.4
-
59
-
-
0034034434
-
Cervene (Nalmefene) in acute ischemic stroke: Final results of a phase III efficacy study
-
The Cervene Stroke Study Investigators
-
Clark WM, Raps EC, Tong DC, Kelly RE: Cervene (Nalmefene) in acute ischemic stroke: Final results of a phase III efficacy study. The Cervene Stroke Study Investigators. Stroke 2000;31:1234-1239.
-
(2000)
Stroke
, vol.31
, pp. 1234-1239
-
-
Clark, W.M.1
Raps, E.C.2
Tong, D.C.3
Kelly, R.E.4
-
60
-
-
0033757829
-
Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging
-
Citicoline 010 Investigators
-
Warach S, Pettigrew LC, Dashe JF, Pullicino P, Lefkowitz DM, Sabounjian L, Harnett K, Schwiderski U, Gammans R: Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 010 Investigators. Ann Neurol 2000;48:713-722.
-
(2000)
Ann Neurol
, vol.48
, pp. 713-722
-
-
Warach, S.1
Pettigrew, L.C.2
Dashe, J.F.3
Pullicino, P.4
Lefkowitz, D.M.5
Sabounjian, L.6
Harnett, K.7
Schwiderski, U.8
Gammans, R.9
-
61
-
-
0030760430
-
A randomized dose-response trial of citicoline in acute ischemic stroke patients
-
Citicoline Stroke Study Group
-
Clark WM, Warach SJ, Pettigrew LC, Gammans RE, Sabounjian LA: A randomized dose-response trial of citicoline in acute ischemic stroke patients. Citicoline Stroke Study Group. Neurology 1997;49:671-678.
-
(1997)
Neurology
, vol.49
, pp. 671-678
-
-
Clark, W.M.1
Warach, S.J.2
Pettigrew, L.C.3
Gammans, R.E.4
Sabounjian, L.A.5
-
62
-
-
0032709479
-
A randomized efficacy trial of citicoline in patients with acute ischemic stroke
-
Clark WM, Williams BJ, Selzer KA, Zweifler RM, Sabounjian LA, Gammans RE: A randomized efficacy trial of citicoline in patients with acute ischemic stroke. Stroke 1999;30:2592-2597.
-
(1999)
Stroke
, vol.30
, pp. 2592-2597
-
-
Clark, W.M.1
Williams, B.J.2
Selzer, K.A.3
Zweifler, R.M.4
Sabounjian, L.A.5
Gammans, R.E.6
-
63
-
-
0035856456
-
A phase III randomized efficacy trial of 2,000 mg citicoline in acute ischemic stroke patients
-
Clark WM, Wechsler LR, Sabounjian LA, Schwiderski UE: A phase III randomized efficacy trial of 2,000 mg citicoline in acute ischemic stroke patients. Neurology 2001;57:1595-1602.
-
(2001)
Neurology
, vol.57
, pp. 1595-1602
-
-
Clark, W.M.1
Wechsler, L.R.2
Sabounjian, L.A.3
Schwiderski, U.E.4
-
64
-
-
85069118326
-
Role of Intravenous Citicoline for Supratentorial Haemorrhage (RICH Study)
-
Role of Intravenous Citicoline for Supratentorial Haemorrhage (RICH Study). Ongoing Clinical Trials Session, 27th Int Stroke Conf, URL: http://stroke.ahajournals.org/, 2002.
-
(2002)
Ongoing Clinical Trials Session, 27th Int Stroke Conf
-
-
-
65
-
-
0346822699
-
BRAINS (Bayer Randomised Acute Ischaemia Neuroprotectant Study)
-
BRAINS (Bayer Randomised Acute Ischaemia Neuroprotectant Study). Stroke 2000;31:2768-2871.
-
(2000)
Stroke
, vol.31
, pp. 2768-2871
-
-
-
67
-
-
0031963673
-
Safety and tolerability of 619C89 after acute stroke
-
Muir KW, Hamilton SJ, Lunnon MW, Hobbiger S, Lees KR: Safety and tolerability of 619C89 after acute stroke. Cerebrovasc Dis 1998;8:31-37.
-
(1998)
Cerebrovasc Dis
, vol.8
, pp. 31-37
-
-
Muir, K.W.1
Hamilton, S.J.2
Lunnon, M.W.3
Hobbiger, S.4
Lees, K.R.5
-
68
-
-
0033777534
-
Phase II clinical trial of sipatrigine (619C89) by continuous infusion in acute stroke
-
Muir KW, Holzapfel L, Lees KR: Phase II clinical trial of sipatrigine (619C89) by continuous infusion in acute stroke. Cerebrovasc Dis 2000;10:431-436.
-
(2000)
Cerebrovasc Dis
, vol.10
, pp. 431-436
-
-
Muir, K.W.1
Holzapfel, L.2
Lees, K.R.3
-
69
-
-
85069110867
-
Double-blind, placebo controlled, safety and efficacy trials of intravenous BMS-204352 in patients with acute stroke
-
Internet Stroke Center
-
POST: Double-blind, placebo controlled, safety and efficacy trials of intravenous BMS-204352 in patients with acute stroke. Ongoing Clinical Trials Session, 25th Int Stroke Conf, Internet Stroke Center. URL: http://www.stro- kecenter.org/, 2002.
-
(2002)
Ongoing Clinical Trials Session, 25th Int Stroke Conf
-
-
-
70
-
-
0031439419
-
Treatment of acute ischemic stroke with piracetam
-
Members of the Piracetam in Acute Stroke Study (PASS) Group
-
De Deyn PP, Reuck JD, Deberdt W, Vlietinck R, Orgogozo JM: Treatment of acute ischemic stroke with piracetam. Members of the Piracetam in Acute Stroke Study (PASS) Group. Stroke 1997;28:2347-2352.
-
(1997)
Stroke
, vol.28
, pp. 2347-2352
-
-
De Deyn, P.P.1
Reuck, J.D.2
Deberdt, W.3
Vlietinck, R.4
Orgogozo, J.M.5
-
71
-
-
0034293293
-
Major Ongoing Stroke Trials: PASS II (Piracetam Acute Stroke Study II)
-
Major Ongoing Stroke Trials: PASS II (Piracetam Acute Stroke Study II). Stroke 2000;31:2536-2542.
-
(2000)
Stroke
, vol.31
, pp. 2536-2542
-
-
-
72
-
-
0027276314
-
Effect of propentofylline on regional cerebral glucose metabolism in acute ischemic stroke
-
Huber M, Kittner B, Hojer C, Fink GR, Neveling M, Heiss WD: Effect of propentofylline on regional cerebral glucose metabolism in acute ischemic stroke. J Cereb Blood Flow Metab 1993;13:526-530.
-
(1993)
J Cereb Blood Flow Metab
, vol.13
, pp. 526-530
-
-
Huber, M.1
Kittner, B.2
Hojer, C.3
Fink, G.R.4
Neveling, M.5
Heiss, W.D.6
-
73
-
-
0021228990
-
Double-blind evaluation of monosialoganglioside (GM1) therapy in stroke
-
Bassi S, Albizzati MG, Sbacchi M, Frattola L, Massarotti M: Double-blind evaluation of monosialoganglioside (GM1) therapy in stroke. J Neurosci Res 1984;12:493-498.
-
(1984)
J Neurosci Res
, vol.12
, pp. 493-498
-
-
Bassi, S.1
Albizzati, M.G.2
Sbacchi, M.3
Frattola, L.4
Massarotti, M.5
-
74
-
-
0024462207
-
GM1 ganglioside therapy in acute ischemic stroke. Italian Acute Stroke Study - Hemodilution + Drug
-
Argentino C, Sacchetti ML, Toni D, Savoini G, D'Arcangelo E, Erminio F, Federico F, Milone FF, Gallai V, Gambi D, et al: GM1 ganglioside therapy in acute ischemic stroke. Italian Acute Stroke Study - Hemodilution + Drug. Stroke 1989;20:1143-1149.
-
(1989)
Stroke
, vol.20
, pp. 1143-1149
-
-
Argentino, C.1
Sacchetti, M.L.2
Toni, D.3
Savoini, G.4
D'Arcangelo, E.5
Erminio, F.6
Federico, F.7
Milone, F.F.8
Gallai, V.9
Gambi, D.10
-
75
-
-
0028450967
-
Ganglioside GM1 in acute ischemic stroke. The SASS Trial
-
Ganglioside GM1 in acute ischemic stroke. The SASS Trial. Stroke 1994;25:1141-1148.
-
(1994)
Stroke
, vol.25
, pp. 1141-1148
-
-
-
76
-
-
0027936299
-
Early treatment of stroke with monosialoganglioside GM-1: Efficacy and safety results of the Early Stroke Trial
-
Lenzi GL, Grigoletto F, Gent M, Roberts RS, Walker MD, Easton JD, Carolei A, Dorsey FC, Rocca WA, Bruno R, et al: Early treatment of stroke with monosialoganglioside GM-1: Efficacy and safety results of the Early Stroke Trial. Stroke 1994;25:1552-1558.
-
(1994)
Stroke
, vol.25
, pp. 1552-1558
-
-
Lenzi, G.L.1
Grigoletto, F.2
Gent, M.3
Roberts, R.S.4
Walker, M.D.5
Easton, J.D.6
Carolei, A.7
Dorsey, F.C.8
Rocca, W.A.9
Bruno, R.10
-
78
-
-
0033782416
-
Apoptosis after experimental stroke: Fact or fashion?
-
MacManus JP, Buchan AM: Apoptosis after experimental stroke: Fact or fashion? J Neurotrauma 2000;17:899-914.
-
(2000)
J Neurotrauma
, vol.17
, pp. 899-914
-
-
MacManus, J.P.1
Buchan, A.M.2
-
79
-
-
85046519028
-
Apoptosis and stroke pathogenesis
-
Rosenblum WI: Apoptosis and stroke pathogenesis. Stroke 1999;30:1154-1155, discussion 1156.
-
(1999)
Stroke
, vol.30
, pp. 1154-1155
-
-
Rosenblum, W.I.1
-
81
-
-
26744478852
-
Neuroprotection in acute ischaemic stroke
-
abstracts of the International Stroke Conference 2001
-
Ladurner G: Neuroprotection in acute ischaemic stroke (abstracts of the International Stroke Conference 2001). Stroke 2001;32:323-c.
-
(2001)
Stroke
, vol.32
-
-
Ladurner, G.1
-
82
-
-
0035833953
-
The Clomethiazole Acute Stroke Study in tissue-type plasminogen activator-treated stroke (CLASS-T): Final results
-
Lyden P, Jacoby M, Schim J, Albers G, Mazzeo P, Ashwood T, Nordlund A, Odergren T: The Clomethiazole Acute Stroke Study in tissue-type plasminogen activator-treated stroke (CLASS-T): Final results. Neurology 2001;57:1199-1205.
-
(2001)
Neurology
, vol.57
, pp. 1199-1205
-
-
Lyden, P.1
Jacoby, M.2
Schim, J.3
Albers, G.4
Mazzeo, P.5
Ashwood, T.6
Nordlund, A.7
Odergren, T.8
-
83
-
-
0001307738
-
Combination Therapy Stroke Trial: rt-PA ± lubeluzole
-
Grotta J: Combination Therapy Stroke Trial: rt-PA ± Lubeluzole. Stroke 2000;31:278.
-
(2000)
Stroke
, vol.31
, pp. 278
-
-
Grotta, J.1
-
84
-
-
0036141160
-
Neuroprotection is unlikely to be effective in humans using current trial designs
-
Grotta J: Neuroprotection is unlikely to be effective in humans using current trial designs. Stroke 2002;33:306-307.
-
(2002)
Stroke
, vol.33
, pp. 306-307
-
-
Grotta, J.1
-
85
-
-
0036142768
-
Neuroprotection is unlikely to be effective in humans using current trial designs: An opposing view
-
Lees KR: Neuroprotection is unlikely to be effective in humans using current trial designs: An opposing view. Stroke 2002;33:308-309.
-
(2002)
Stroke
, vol.33
, pp. 308-309
-
-
Lees, K.R.1
-
86
-
-
0036141161
-
Neuroprotection: Establishing proof of concept in human stroke
-
Davis SM, Donnan GA: Neuroprotection: Establishing proof of concept in human stroke. Stroke 2002;33:309-310.
-
(2002)
Stroke
, vol.33
, pp. 309-310
-
-
Davis, S.M.1
Donnan, G.A.2
|