Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs

PLoS ONE

Volumn 3, Issue 11, 2008, Pages

  Broughton, Susan ^a   Alic, Nazif ^a   Slack, Cathy ^a   Bass, Timothy ^a   Ikeya, Tomoatsu ^a   Vinti, Giovanna ^a   Tommasi, Anna Maria ^a,c   Driege, Yasmine ^a,d   Hafen, Ernst ^b   Partridge, Linda ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA PROTEIN; MESSENGER RNA; SOMATOMEDIN B; TREHALOSE; DIAP2 PROTEIN, DROSOPHILA; GLYCOGEN; INHIBITOR OF APOPTOSIS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; DROSOPHILA; FEMALE; FERTILITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC VARIABILITY; HEMOLYMPH; LIFE CYCLE; LIFESPAN; LIPID METABOLISM; LIPID STORAGE; NEUROSECRETORY CELL; NONHUMAN; OXIDATIVE STRESS; PHENOTYPIC VARIATION; RNA INTERFERENCE; STARVATION; UPREGULATION; ANIMAL; BLOOD; GENETICS; LONGEVITY; METABOLISM; PHENOTYPE; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GLYCOGEN; INHIBITOR OF APOPTOSIS PROTEINS; LIPID METABOLISM; LONGEVITY; MUTAGENESIS, INSERTIONAL; OXIDATIVE STRESS; PHENOTYPE; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TREHALOSE;

EID: 56649121807     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003721     Document Type: Article

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