Intraputamenal infusion of GDNF in aged rhesus monkeys: Distribution and dopaminergic effects

Journal of Comparative Neurology

Volumn 461, Issue 2, 2003, Pages 250-261

  Ai, Yi ^a   Markesbery, William ^a   Zhang, Zhiming ^a   Grondin, Richard ^a   Elseberry, Dennis ^b   Gerhardt, Greg A ^a   Gash, Don M ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b MEDTRONIC INC   (United States)

Author keywords

Basal ganglia; Dopamine neurons; Substantia nigra; Trophic factors

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; TYROSINE 3 MONOOXYGENASE;

AGED; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANISOTROPY; ARTICLE; BRAIN REGION; BRAIN TISSUE; CATHETER; CAUDATE NUCLEUS; CELL COUNT; CELL DENSITY; CELL LABELING; CELL SIZE; CONTINUOUS INFUSION; CONTROLLED STUDY; CORPUS CALLOSUM; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG EFFECT; DRUG INFUSION; DRUG TRANSPORT; ENZYME ASSAY; FEMALE; FRONTAL CORTEX; GLOBUS PALLIDUS; HEMISPHERIC DOMINANCE; LOCUS CERULEUS; NERVE CELL STIMULATION; NERVE FIBER; NEUROANATOMY; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PUTAMEN; PYRAMIDAL TRACT; QUANTITATIVE ANALYSIS; RHESUS MONKEY; SPINAL CORD; SUBSTANTIA NIGRA; THALAMUS ANTERIOR NUCLEUS; TISSUE INJURY;

AGING; ANIMALS; AXONAL TRANSPORT; CELL COUNT; CELL SIZE; DIFFUSION; DOPAMINE; DRUG ADMINISTRATION ROUTES; DRUG ADMINISTRATION SCHEDULE; FEMALE; FUNCTIONAL LATERALITY; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOHISTOCHEMISTRY; MACACA MULATTA; MICROINJECTIONS; NERVE GROWTH FACTORS; NEURAL PATHWAYS; NEURONS; PARKINSON DISEASE; PUTAMEN; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 0037911432     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.10689     Document Type: Article

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