-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin 2008; 58: 71-96.
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
3
-
-
0000972520
-
Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture
-
Rowe WP, Huebner RJ, Gilmore LK, Parrott RH, Ward TG. Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture. Proc Soc Exp Biol Med 1953; 84: 570-3.
-
(1953)
Proc Soc Exp Biol Med
, vol.84
, pp. 570-573
-
-
Rowe, W.P.1
Huebner, R.J.2
Gilmore, L.K.3
Parrott, R.H.4
Ward, T.G.5
-
4
-
-
77049281450
-
Studies on the use of viruses in the treatment of carcinoma of the cervix
-
Huebner RJ, Rowe WP, Schatten WE, Smith RR, Thomas LB. Studies on the use of viruses in the treatment of carcinoma of the cervix. Cancer 1956; 9: 1211-8.
-
(1956)
Cancer
, vol.9
, pp. 1211-1218
-
-
Huebner, R.J.1
Rowe, W.P.2
Schatten, W.E.3
Smith, R.R.4
Thomas, L.B.5
-
5
-
-
0035342191
-
Cancer gene therapy by adenovirus-mediated gene transfer
-
Wu Q, Moyana T, Xiang J. Cancer gene therapy by adenovirus-mediated gene transfer. Curr Gene Ther 2001; 1: 101-22.
-
(2001)
Curr Gene Ther
, vol.1
, pp. 101-122
-
-
Wu, Q.1
Moyana, T.2
Xiang, J.3
-
6
-
-
34848904829
-
Adenoviral vectors for gene therapy
-
Douglas JT. Adenoviral vectors for gene therapy. Mol Biotechnol 2007; 36: 71-80.
-
(2007)
Mol Biotechnol
, vol.36
, pp. 71-80
-
-
Douglas, J.T.1
-
7
-
-
0031052263
-
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
-
Bergelson JM, Cunningham JA, Droguett G, et al. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 1997; 275: 1320-3.
-
(1997)
Science
, vol.275
, pp. 1320-1323
-
-
Bergelson, J.M.1
Cunningham, J.A.2
Droguett, G.3
-
8
-
-
0027166647
-
Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment
-
Wickham TJ, Mathias P, Cheresh DA, Nemerow GR. Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 1993; 73: 309-19.
-
(1993)
Cell
, vol.73
, pp. 309-319
-
-
Wickham, T.J.1
Mathias, P.2
Cheresh, D.A.3
Nemerow, G.R.4
-
9
-
-
35348977671
-
Cancer-targeting gene therapy using tropism-modified adenovirus
-
Tanaka T, Kuroki M, Hamada H, et al. Cancer-targeting gene therapy using tropism-modified adenovirus. Anticancer Res 2007; 27: 3679-84.
-
(2007)
Anticancer Res
, vol.27
, pp. 3679-3684
-
-
Tanaka, T.1
Kuroki, M.2
Hamada, H.3
-
10
-
-
0033756217
-
Update on adenovirus and its vectors
-
Russell WC. Update on adenovirus and its vectors. J Gen Virol 2000; 81: 2573-604.
-
(2000)
J Gen Virol
, vol.81
, pp. 2573-2604
-
-
Russell, W.C.1
-
11
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr CJ, McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002; 2: 103-12.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
12
-
-
30044439886
-
Adenovirus p53 gene therapy
-
Roth JA. Adenovirus p53 gene therapy. Expert Opin Biol Ther 2006; 6: 55-61.
-
(2006)
Expert Opin Biol Ther
, vol.6
, pp. 55-61
-
-
Roth, J.A.1
-
13
-
-
0028129836
-
Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells
-
Van Meir EG, Polverini PJ, Chazin VR, et al. Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells. Nat Genet 1994; 8: 171-6.
-
(1994)
Nat Genet
, vol.8
, pp. 171-176
-
-
Van Meir, E.G.1
Polverini, P.J.2
Chazin, V.R.3
-
14
-
-
0041662272
-
Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence
-
Takaoka A, Hayakawa S, Yanai H, et al. Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 2003; 424: 516-23.
-
(2003)
Nature
, vol.424
, pp. 516-523
-
-
Takaoka, A.1
Hayakawa, S.2
Yanai, H.3
-
16
-
-
0032101647
-
Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer
-
Bouvet M, Ellis LM, Nishizaki M, et al. Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer. Cancer Res 1998; 58: 2288-92.
-
(1998)
Cancer Res
, vol.58
, pp. 2288-2292
-
-
Bouvet, M.1
Ellis, L.M.2
Nishizaki, M.3
-
17
-
-
0345256634
-
The role of p53 in chemosensitivity and radiosensitivity
-
El-Deiry WS. The role of p53 in chemosensitivity and radiosensitivity. Oncogene 2003; 22: 7486-95.
-
(2003)
Oncogene
, vol.22
, pp. 7486-7495
-
-
El-Deiry, W.S.1
-
18
-
-
24944454988
-
Current status of gendicine in China: Recombinant human Ad-p53 agent for treatment of cancers
-
Peng Z. Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers. Hum Gene Ther 2005; 16: 1016-27.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 1016-1027
-
-
Peng, Z.1
-
19
-
-
34248231803
-
-
INGN 201: Ad-p53, Ad5CMV-p53, adenoviral p53, p53 gene therapy - introgen, RPR/INGN 201. Drugs RD 2007; 8: 176-87.
-
INGN 201: Ad-p53, Ad5CMV-p53, adenoviral p53, p53 gene therapy - introgen, RPR/INGN 201. Drugs RD 2007; 8: 176-87.
-
-
-
-
20
-
-
33744529601
-
Phase I/II adenoviral p53 gene therapy for chemoradiation resistant advanced esophageal squamous cell carcinoma
-
Shimada H, Matsubara H, Shiratori T, et al. Phase I/II adenoviral p53 gene therapy for chemoradiation resistant advanced esophageal squamous cell carcinoma. Cancer Sci 2006; 97: 554-61.
-
(2006)
Cancer Sci
, vol.97
, pp. 554-561
-
-
Shimada, H.1
Matsubara, H.2
Shiratori, T.3
-
21
-
-
0029802927
-
Adenovirus-mediated retinoblastoma gene therapy suppresses spontaneous pituitary melanotroph tumors in Rb+/- mice
-
Riley DJ, Nikitin AY, Lee WH. Adenovirus-mediated retinoblastoma gene therapy suppresses spontaneous pituitary melanotroph tumors in Rb+/- mice. Nat Med 1996; 2: 1316-21.
-
(1996)
Nat Med
, vol.2
, pp. 1316-1321
-
-
Riley, D.J.1
Nikitin, A.Y.2
Lee, W.H.3
-
22
-
-
0031813862
-
Suppression of human glioma growth by adenovirus-mediated Rb gene transfer
-
Fueyo J, Gomez-Manzano C, Yung WK, et al. Suppression of human glioma growth by adenovirus-mediated Rb gene transfer. Neurology 1998; 50: 1307-15.
-
(1998)
Neurology
, vol.50
, pp. 1307-1315
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Yung, W.K.3
-
23
-
-
0037442425
-
Adenoviral-mediated retinoblastoma 94 produces rapid telomere erosion, chromosomal crisis, and caspase-dependent apoptosis in bladder cancer and immortalized human urothelial cells but not in normal urothelial cells
-
Zhang X, Multani AS, Zhou JH, et al. Adenoviral-mediated retinoblastoma 94 produces rapid telomere erosion, chromosomal crisis, and caspase-dependent apoptosis in bladder cancer and immortalized human urothelial cells but not in normal urothelial cells. Cancer Res 2003; 63: 760-5.
-
(2003)
Cancer Res
, vol.63
, pp. 760-765
-
-
Zhang, X.1
Multani, A.S.2
Zhou, J.H.3
-
24
-
-
0035709610
-
Tissue-specific expression of an anti-proliferative hybrid transgene from the human smooth muscle alpha-actin promoter suppresses smooth muscle cell proliferation and neointima formation
-
Wills KN, Mano T, Avanzini JB, et al. Tissue-specific expression of an anti-proliferative hybrid transgene from the human smooth muscle alpha-actin promoter suppresses smooth muscle cell proliferation and neointima formation. Gene Ther 2001; 8: 1847-54.
-
(2001)
Gene Ther
, vol.8
, pp. 1847-1854
-
-
Wills, K.N.1
Mano, T.2
Avanzini, J.B.3
-
25
-
-
33847670886
-
Induction of apoptosis by tumor suppressor FHIT via death receptor signaling pathway in human lung cancer cells
-
Deng WG, Nishizaki M, Fang B, Roth JA, Ji L. Induction of apoptosis by tumor suppressor FHIT via death receptor signaling pathway in human lung cancer cells. Biochem Biophys Res Commun 2007; 355: 993-9.
-
(2007)
Biochem Biophys Res Commun
, vol.355
, pp. 993-999
-
-
Deng, W.G.1
Nishizaki, M.2
Fang, B.3
Roth, J.A.4
Ji, L.5
-
26
-
-
1842529509
-
Gene therapy progress and prospects: Cancer gene therapy using tumour suppressor genes
-
McNeish IA, Bell SJ, Lemoine NR. Gene therapy progress and prospects: cancer gene therapy using tumour suppressor genes. Gene Ther 2004; 11: 497-503.
-
(2004)
Gene Ther
, vol.11
, pp. 497-503
-
-
McNeish, I.A.1
Bell, S.J.2
Lemoine, N.R.3
-
27
-
-
38449089876
-
-
Qiu Z, Cui FL, Xu CL, Gu ZQ, Sun YH. et al.Suppression of invasion and angiogenesis in human prostate cancer PC-3 cells by adenovirus-mediated co-transfer of PTEN and P27]. Zhonghua Nan Ke Xue 2007; 13: 201-5.
-
Qiu Z, Cui FL, Xu CL, Gu ZQ, Sun YH. et al.Suppression of invasion and angiogenesis in human prostate cancer PC-3 cells by adenovirus-mediated co-transfer of PTEN and P27]. Zhonghua Nan Ke Xue 2007; 13: 201-5.
-
-
-
-
28
-
-
31144446196
-
Adenovirus-mediated Ink4a/ARF gene transfer significantly suppressed the growth of pancreatic carcinoma cells
-
Chen F, Li Y, Lu Z, Gao J, Chen J. Adenovirus-mediated Ink4a/ARF gene transfer significantly suppressed the growth of pancreatic carcinoma cells. Cancer Biol Ther 2005; 4: 1348-54.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 1348-1354
-
-
Chen, F.1
Li, Y.2
Lu, Z.3
Gao, J.4
Chen, J.5
-
29
-
-
44949264134
-
In vivo restoration of RhoB expression leads to ovarian tumor regression
-
Couderc B, Pradines A, Rafii A, et al. In vivo restoration of RhoB expression leads to ovarian tumor regression. Cancer Gene Ther 2008; 15: 456-64.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 456-464
-
-
Couderc, B.1
Pradines, A.2
Rafii, A.3
-
30
-
-
31444446694
-
The tumor suppressor activity induced by adenovirus-mediated BRCA1 overexpression is not restricted to breast cancers
-
Marot D, Opolon P, Brailly-Tabard S, et al. The tumor suppressor activity induced by adenovirus-mediated BRCA1 overexpression is not restricted to breast cancers. Gene Ther 2006; 13: 235-44.
-
(2006)
Gene Ther
, vol.13
, pp. 235-244
-
-
Marot, D.1
Opolon, P.2
Brailly-Tabard, S.3
-
31
-
-
0033975549
-
The growth inhibitory effect of p21 adenovirus on human bladder cancer cells
-
Hall MC, Li Y, Pong RC, et al. The growth inhibitory effect of p21 adenovirus on human bladder cancer cells. J Urol 2000; 163: 1033-8.
-
(2000)
J Urol
, vol.163
, pp. 1033-1038
-
-
Hall, M.C.1
Li, Y.2
Pong, R.C.3
-
32
-
-
36348986653
-
Ad-PUMA sensitizes drug-resistant choriocarcinoma cells to chemotherapeutic agents
-
Chen Y, Qian H, Wang H, et al. Ad-PUMA sensitizes drug-resistant choriocarcinoma cells to chemotherapeutic agents. Gynecol Oncol 2007; 107: 505-12.
-
(2007)
Gynecol Oncol
, vol.107
, pp. 505-512
-
-
Chen, Y.1
Qian, H.2
Wang, H.3
-
33
-
-
1542409979
-
Changes in the apoptotic and survival signaling in cancer cells and their potential therapeutic implications
-
Kabore AF, Johnston JB, Gibson SB. Changes in the apoptotic and survival signaling in cancer cells and their potential therapeutic implications. Curr Cancer Drug Targets 2004; 4: 147-63.
-
(2004)
Curr Cancer Drug Targets
, vol.4
, pp. 147-163
-
-
Kabore, A.F.1
Johnston, J.B.2
Gibson, S.B.3
-
34
-
-
37249067981
-
Apoptosis pathways and oncolytic adenoviral vectors: Promising targets and tools to overcome therapy resistance of malignant melanoma
-
Eberle J, Fecker LF, Hossini AM, Kurbanov BM, Fechner H. Apoptosis pathways and oncolytic adenoviral vectors: promising targets and tools to overcome therapy resistance of malignant melanoma. Exp Dermatol 2008; 17: 1-11.
-
(2008)
Exp Dermatol
, vol.17
, pp. 1-11
-
-
Eberle, J.1
Fecker, L.F.2
Hossini, A.M.3
Kurbanov, B.M.4
Fechner, H.5
-
35
-
-
0035266163
-
EphA2 overexpression causes tumorigenesis of mammary epithelial cells
-
Zelinski DP, Zantek ND, Stewart JC, Irizarry AR, Kinch MS. EphA2 overexpression causes tumorigenesis of mammary epithelial cells. Cancer Res 2001; 61: 2301-6.
-
(2001)
Cancer Res
, vol.61
, pp. 2301-2306
-
-
Zelinski, D.P.1
Zantek, N.D.2
Stewart, J.C.3
Irizarry, A.R.4
Kinch, M.S.5
-
36
-
-
0032708010
-
Overexpression of the EphA2 tyrosine kinase in prostate cancer
-
Walker-Daniels J, Coffman K, Azimi M, et al. Overexpression of the EphA2 tyrosine kinase in prostate cancer. Prostate 1999; 41: 275-80.
-
(1999)
Prostate
, vol.41
, pp. 275-280
-
-
Walker-Daniels, J.1
Coffman, K.2
Azimi, M.3
-
37
-
-
31544478574
-
Expression of EphA2 and Ephrin A-1 in carcinoma of the urinary bladder
-
Abraham S, Knapp DW, Cheng L, et al. Expression of EphA2 and Ephrin A-1 in carcinoma of the urinary bladder. Clin Cancer Res 2006; 12: 353-60.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 353-360
-
-
Abraham, S.1
Knapp, D.W.2
Cheng, L.3
-
38
-
-
0032834125
-
E-cadherin regulates the function of the EphA2 receptor tyrosine kinase
-
Zantek ND, Azimi M, Fedor-Chaiken M, et al. E-cadherin regulates the function of the EphA2 receptor tyrosine kinase. Cell Growth Differ 1999; 10: 629-38.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 629-638
-
-
Zantek, N.D.1
Azimi, M.2
Fedor-Chaiken, M.3
-
39
-
-
0037217912
-
Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer
-
Kinch MS, Carles-Kinch K. Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer. Clin Exp Metastasis 2003; 20: 59-68.
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 59-68
-
-
Kinch, M.S.1
Carles-Kinch, K.2
-
40
-
-
0037093097
-
Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior
-
Carles-Kinch K, Kilpatrick KE, Stewart JC, Kinch MS. Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior. Cancer Res 2002; 62: 2840-7.
-
(2002)
Cancer Res
, vol.62
, pp. 2840-2847
-
-
Carles-Kinch, K.1
Kilpatrick, K.E.2
Stewart, J.C.3
Kinch, M.S.4
-
41
-
-
4444257965
-
Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1
-
Noblitt LW, Bangari DS, Shukla S, et al. Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1. Cancer Gene Ther 2004; 11: 757-66.
-
(2004)
Cancer Gene Ther
, vol.11
, pp. 757-766
-
-
Noblitt, L.W.1
Bangari, D.S.2
Shukla, S.3
-
42
-
-
10844277420
-
Immunocompetent mouse model of breast cancer for preclinical testing of EphA2-targeted therapy
-
Noblitt LW, Bangari DS, Shukla S, Mohammed S, Mittal SK. Immunocompetent mouse model of breast cancer for preclinical testing of EphA2-targeted therapy. Cancer Gene Ther 2005; 12: 46-53.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 46-53
-
-
Noblitt, L.W.1
Bangari, D.S.2
Shukla, S.3
Mohammed, S.4
Mittal, S.K.5
-
43
-
-
33750736070
-
Gene therapy using adenovirus-mediated full-length anti-HER-2 antibody for HER-2 overexpression cancers
-
Jiang M, Shi W, Zhang Q, et al. Gene therapy using adenovirus-mediated full-length anti-HER-2 antibody for HER-2 overexpression cancers. Clin Cancer Res 2006; 12: 6179-85.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6179-6185
-
-
Jiang, M.1
Shi, W.2
Zhang, Q.3
-
44
-
-
0036196127
-
Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv
-
Arafat WO, Gomez-Navarro J, Buchsbaum DJ, et al. Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv. Gene Ther 2002; 9: 256-62.
-
(2002)
Gene Ther
, vol.9
, pp. 256-262
-
-
Arafat, W.O.1
Gomez-Navarro, J.2
Buchsbaum, D.J.3
-
45
-
-
0023914010
-
Association between an oncogene and an anti-oncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product
-
Whyte P, Buchkovich KJ, Horowitz JM, et al. Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 1988; 334: 124-9.
-
(1988)
Nature
, vol.334
, pp. 124-129
-
-
Whyte, P.1
Buchkovich, K.J.2
Horowitz, J.M.3
-
46
-
-
0031451158
-
Viral transactivating proteins
-
Flint J, Shenk T. Viral transactivating proteins. Annu Rev Genet 1997; 31: 177-212.
-
(1997)
Annu Rev Genet
, vol.31
, pp. 177-212
-
-
Flint, J.1
Shenk, T.2
-
47
-
-
0032504783
-
p14ARF links the tumour suppressors RB and p53
-
Bates S, Phillips AC, Clark PA, et al. p14ARF links the tumour suppressors RB and p53. Nature 1998; 395: 124-5.
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
Phillips, A.C.2
Clark, P.A.3
-
48
-
-
0026560315
-
Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein
-
Yew PR, Berk AJ. Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein. Nature 1992; 357: 82-5.
-
(1992)
Nature
, vol.357
, pp. 82-85
-
-
Yew, P.R.1
Berk, A.J.2
-
49
-
-
0030001373
-
Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor
-
Dobner T, Horikoshi N, Rubenwolf S, Shenk T. Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor. Science 1996; 272: 1470-3.
-
(1996)
Science
, vol.272
, pp. 1470-1473
-
-
Dobner, T.1
Horikoshi, N.2
Rubenwolf, S.3
Shenk, T.4
-
50
-
-
0028113218
-
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
-
Boyd JM, Malstrom S, Subramanian T, et al. Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 1994; 79: 341-51.
-
(1994)
Cell
, vol.79
, pp. 341-351
-
-
Boyd, J.M.1
Malstrom, S.2
Subramanian, T.3
-
51
-
-
0026639932
-
The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins
-
Rao L, Debbas M, Sabbatini P, et al. The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins. Proc Natl Acad Sci USA 1992; 89: 7742-6.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7742-7746
-
-
Rao, L.1
Debbas, M.2
Sabbatini, P.3
-
52
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff JR, Kirn DH, Williams A, et al. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 1996; 274: 373-6.
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
-
53
-
-
12944328660
-
A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer
-
Ganly I, Kirn D, Eckhardt G, et al. A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer. Clin Cancer Res 2000; 6: 798-806.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 798-806
-
-
Ganly, I.1
Kirn, D.2
Eckhardt, G.3
-
54
-
-
27944433469
-
Oncolytic viral therapies - the clinical experience
-
Aghi M, Martuza RL. Oncolytic viral therapies - the clinical experience. Oncogene 2005; 24: 7802-16.
-
(2005)
Oncogene
, vol.24
, pp. 7802-7816
-
-
Aghi, M.1
Martuza, R.L.2
-
55
-
-
0035134629
-
Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: What have we learned?
-
Kirn D. Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned? Gene Ther 2001; 8: 89-98.
-
(2001)
Gene Ther
, vol.8
, pp. 89-98
-
-
Kirn, D.1
-
56
-
-
0030917202
-
ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
-
Heise C, Sampson-Johannes A, Williams A, et al. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat Med 1997; 3: 639-45.
-
(1997)
Nat Med
, vol.3
, pp. 639-645
-
-
Heise, C.1
Sampson-Johannes, A.2
Williams, A.3
-
57
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri FR, Nemunaitis J, Ganly I, et al. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 2000; 6: 879-85.
-
(2000)
Nat Med
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
58
-
-
10244253939
-
Intra-tumor injection of H101, a recombinant adenovirus, in combination with chemotherapy in patients with advanced cancers: A pilot phase II clinical trial
-
Lu W, Zheng S, Li XF, et al. Intra-tumor injection of H101, a recombinant adenovirus, in combination with chemotherapy in patients with advanced cancers: a pilot phase II clinical trial. World J Gastroenterol 2004; 10: 3634-8.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 3634-3638
-
-
Lu, W.1
Zheng, S.2
Li, X.F.3
-
59
-
-
0033809680
-
Oncolytic potential of E1B 55 kDa-deleted YKL-1 recombinant adenovirus: Correlation with p53 functional status
-
Lee H, Kim J, Lee B, et al. Oncolytic potential of E1B 55 kDa-deleted YKL-1 recombinant adenovirus: correlation with p53 functional status. Int J Cancer 2000; 88: 454-63.
-
(2000)
Int J Cancer
, vol.88
, pp. 454-463
-
-
Lee, H.1
Kim, J.2
Lee, B.3
-
60
-
-
33847389767
-
Clinical trials with oncolytic adenovirus in China
-
Yu W, Fang H. Clinical trials with oncolytic adenovirus in China. Curr Cancer Drug Targets 2007; 7: 141-8.
-
(2007)
Curr Cancer Drug Targets
, vol.7
, pp. 141-148
-
-
Yu, W.1
Fang, H.2
-
61
-
-
28744437659
-
Phase III randomized clinical trial of intratumoral injection of E1B gene-deleted adenovirus (H101) combined with cisplatin-based chemotherapy in treating squamous cell cancer of head and neck or esophagus
-
Xia ZJ, Chang JH, Zhang L, et al. Phase III randomized clinical trial of intratumoral injection of E1B gene-deleted adenovirus (H101) combined with cisplatin-based chemotherapy in treating squamous cell cancer of head and neck or esophagus. Ai Zheng 2004; 23: 1666-70.
-
(2004)
Ai Zheng
, vol.23
, pp. 1666-1670
-
-
Xia, Z.J.1
Chang, J.H.2
Zhang, L.3
-
62
-
-
0031743945
-
Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells
-
Rothmann T, Hengstermann A, Whitaker NJ, Scheffner M, zur Hausen H. Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells. J Virol 1998; 72: 9470-8.
-
(1998)
J Virol
, vol.72
, pp. 9470-9478
-
-
Rothmann, T.1
Hengstermann, A.2
Whitaker, N.J.3
Scheffner, M.4
zur Hausen, H.5
-
63
-
-
0033105423
-
Targeting the replication of adenoviral gene therapy vectors to lung cancer cells: The importance of the adenoviral E1b-55kD gene
-
Hay JG, Shapiro N, Sauthoff H, et al. Targeting the replication of adenoviral gene therapy vectors to lung cancer cells: the importance of the adenoviral E1b-55kD gene. Hum Gene Ther 1999; 10: 579-90.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 579-590
-
-
Hay, J.G.1
Shapiro, N.2
Sauthoff, H.3
-
64
-
-
0036468548
-
Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts
-
Geoerger B, Grill J, Opolon P, et al. Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts. Cancer Res 2002; 62: 764-72.
-
(2002)
Cancer Res
, vol.62
, pp. 764-772
-
-
Geoerger, B.1
Grill, J.2
Opolon, P.3
-
65
-
-
0034658418
-
Efficient induction of cell death by adenoviruses requires binding of E1B55k and p53
-
Dix BR, O'Carroll SJ, Myers CJ, Edwards SJ, Braithwaite AW. Efficient induction of cell death by adenoviruses requires binding of E1B55k and p53. Cancer Res 2000; 60: 2666-72.
-
(2000)
Cancer Res
, vol.60
, pp. 2666-2672
-
-
Dix, B.R.1
O'Carroll, S.J.2
Myers, C.J.3
Edwards, S.J.4
Braithwaite, A.W.5
-
66
-
-
0031697770
-
p53-dependent cell death/ apoptosis is required for a productive adenovirus infection
-
Hall AR, Dix BR, O'Carroll SJ, Braithwaite AW. p53-dependent cell death/ apoptosis is required for a productive adenovirus infection. Nat Med 1998; 4: 1068-72.
-
(1998)
Nat Med
, vol.4
, pp. 1068-1072
-
-
Hall, A.R.1
Dix, B.R.2
O'Carroll, S.J.3
Braithwaite, A.W.4
-
67
-
-
0033539104
-
Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and DeltaE1B adenovirus replication in human cells
-
Steegenga WT, Riteco N, Bos JL. Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and DeltaE1B adenovirus replication in human cells. Oncogene 1999; 18: 5032-43.
-
(1999)
Oncogene
, vol.18
, pp. 5032-5043
-
-
Steegenga, W.T.1
Riteco, N.2
Bos, J.L.3
-
68
-
-
0033623250
-
Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015)
-
Ries SJ, Brandts CH, Chung AS, et al. Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015). Nat Med 2000; 6: 1128-33.
-
(2000)
Nat Med
, vol.6
, pp. 1128-1133
-
-
Ries, S.J.1
Brandts, C.H.2
Chung, A.S.3
-
69
-
-
0142092408
-
Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants
-
Hann B, Balmain A. Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants. J Virol 2003; 77: 11588-95.
-
(2003)
J Virol
, vol.77
, pp. 11588-11595
-
-
Hann, B.1
Balmain, A.2
-
70
-
-
19944363519
-
Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity
-
O'Shea CC, Johnson L, Bagus B, et al. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity. Cancer Cell 2004; 6: 611-23.
-
(2004)
Cancer Cell
, vol.6
, pp. 611-623
-
-
O'Shea, C.C.1
Johnson, L.2
Bagus, B.3
-
71
-
-
0035015925
-
Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?
-
Dix BR, Edwards SJ, Braithwaite AW. Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway? J Virol 2001; 75: 5443-7.
-
(2001)
J Virol
, vol.75
, pp. 5443-5447
-
-
Dix, B.R.1
Edwards, S.J.2
Braithwaite, A.W.3
-
72
-
-
0021363662
-
Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis
-
Babiss LE, Ginsberg HS. Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis. J Virol 1984; 50: 202-12.
-
(1984)
J Virol
, vol.50
, pp. 202-212
-
-
Babiss, L.E.1
Ginsberg, H.S.2
-
73
-
-
0035050154
-
Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein
-
Shen Y, Kitzes G, Nye JA, Fattaey A, Hermiston T. Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein. J Virol 2001; 75: 4297-307.
-
(2001)
J Virol
, vol.75
, pp. 4297-4307
-
-
Shen, Y.1
Kitzes, G.2
Nye, J.A.3
Fattaey, A.4
Hermiston, T.5
-
74
-
-
0033782862
-
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
-
Heise C, Hermiston T, Johnson L, et al. An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy. Nat Med 2000; 6: 1134-9.
-
(2000)
Nat Med
, vol.6
, pp. 1134-1139
-
-
Heise, C.1
Hermiston, T.2
Johnson, L.3
-
75
-
-
0034610723
-
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo
-
Fueyo J, Gomez-Manzano C, Alemany R, et al. A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene 2000; 19: 2-12.
-
(2000)
Oncogene
, vol.19
, pp. 2-12
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Alemany, R.3
-
76
-
-
33947702021
-
-
Page JG, Tian B, Schweikart K, et al. Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer. Am J Obstet Gynecol 2007; 196: 389.e1-389.e10.
-
Page JG, Tian B, Schweikart K, et al. Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer. Am J Obstet Gynecol 2007; 196: 389.e1-389.e10.
-
-
-
-
77
-
-
19044386714
-
Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents
-
Johnson L, Shen A, Boyle L, et al. Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents. Cancer Cell 2002; 1: 325-37.
-
(2002)
Cancer Cell
, vol.1
, pp. 325-337
-
-
Johnson, L.1
Shen, A.2
Boyle, L.3
-
78
-
-
0032526693
-
The molecular basis of viral oncolysis: Usurpation of the Ras signaling pathway by reovirus
-
Strong JE, Coffey MC, Tang D, Sabinin P, Lee PW. The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus. Embo J 1998; 17: 3351-62.
-
(1998)
Embo J
, vol.17
, pp. 3351-3362
-
-
Strong, J.E.1
Coffey, M.C.2
Tang, D.3
Sabinin, P.4
Lee, P.W.5
-
79
-
-
0035109180
-
Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis
-
Balachandran S, Porosnicu M, Barber GN. Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis. J Virol 2001; 75: 3474-9.
-
(2001)
J Virol
, vol.75
, pp. 3474-3479
-
-
Balachandran, S.1
Porosnicu, M.2
Barber, G.N.3
-
80
-
-
0029051672
-
Involvement of the double-stranded-RNA-dependent kinase PKR in interferon expression and interferon-mediated antiviral activity
-
Der SD, Lau AS. Involvement of the double-stranded-RNA-dependent kinase PKR in interferon expression and interferon-mediated antiviral activity. Proc Natl Acad Sci USA 1995; 92: 8841-5.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8841-8845
-
-
SD, D.1
Lau, A.S.2
-
81
-
-
34347225099
-
The dsRNA protein kinase PKR: Virus and cell control
-
Garcia MA, Meurs EF, Esteban M. The dsRNA protein kinase PKR: virus and cell control. Biochimie 2007; 89: 799-811.
-
(2007)
Biochimie
, vol.89
, pp. 799-811
-
-
Garcia, M.A.1
Meurs, E.F.2
Esteban, M.3
-
82
-
-
0022447264
-
Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase
-
Kitajewski J, Schneider RJ, Safer B, et al. Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase. Cell 1986; 45: 195-200.
-
(1986)
Cell
, vol.45
, pp. 195-200
-
-
Kitajewski, J.1
Schneider, R.J.2
Safer, B.3
-
83
-
-
0022416367
-
Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection
-
Schneider RJ, Safer B, Munemitsu SM, Samuel CE, Shenk T. Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection. Proc Natl Acad Sci USA 1985; 82: 4321-5.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 4321-4325
-
-
Schneider, R.J.1
Safer, B.2
Munemitsu, S.M.3
Samuel, C.E.4
Shenk, T.5
-
84
-
-
0141592775
-
Ras-dependent oncolysis with an adenovirus VAI mutant
-
Cascallo M, Capella G, Mazo A, Alemany R. Ras-dependent oncolysis with an adenovirus VAI mutant. Cancer Res 2003; 63: 5544-50.
-
(2003)
Cancer Res
, vol.63
, pp. 5544-5550
-
-
Cascallo, M.1
Capella, G.2
Mazo, A.3
Alemany, R.4
-
85
-
-
13944270613
-
Virus-associated RNA I-deleted adenovirus, a potential oncolytic agent targeting EBV-associated tumors
-
Wang Y, Xue SA, Hallden G, et al. Virus-associated RNA I-deleted adenovirus, a potential oncolytic agent targeting EBV-associated tumors. Cancer Res 2005; 65: 1523-31.
-
(2005)
Cancer Res
, vol.65
, pp. 1523-1531
-
-
Wang, Y.1
Xue, S.A.2
Hallden, G.3
-
86
-
-
0034628552
-
Deletion of the adenoviral E1b-19kD gene enhances tumor cell killing of a replicating adenoviral vector
-
Sauthoff H, Heitner S, Rom WN, Hay JG. Deletion of the adenoviral E1b-19kD gene enhances tumor cell killing of a replicating adenoviral vector. Hum Gene Ther 2000; 11: 379-88.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 379-388
-
-
Sauthoff, H.1
Heitner, S.2
Rom, W.N.3
Hay, J.G.4
-
87
-
-
0034917855
-
Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved - deletion of the viral E1b-19-kD gene increases the viral oncolytic effect
-
Harrison D, Sauthoff H, Heitner S, et al. Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved - deletion of the viral E1b-19-kD gene increases the viral oncolytic effect. Hum Gene Ther 2001; 12: 1323-32.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1323-1332
-
-
Harrison, D.1
Sauthoff, H.2
Heitner, S.3
-
88
-
-
0036708228
-
Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy
-
Kim J, Cho JY, Kim JH, Jung KC, Yun CO. Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy. Cancer Gene Ther 2002; 9: 725-36.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 725-736
-
-
Kim, J.1
Cho, J.Y.2
Kim, J.H.3
Jung, K.C.4
Yun, C.O.5
-
89
-
-
3042751185
-
Pathways used by adenovirus E1B 19K to inhibit apoptosis
-
Degenhardt K, Perez D, White E. Pathways used by adenovirus E1B 19K to inhibit apoptosis. Symp Soc Exp Biol 2000; 52: 241-51.
-
(2000)
Symp Soc Exp Biol
, vol.52
, pp. 241-251
-
-
Degenhardt, K.1
Perez, D.2
White, E.3
-
90
-
-
3042735443
-
An E1B-19 kDa gene deletion mutant adenovirus demonstrates tumor necrosis factor-enhanced cancer selectivity and enhanced oncolytic potency
-
Liu TC, Hallden G, Wang Y, et al. An E1B-19 kDa gene deletion mutant adenovirus demonstrates tumor necrosis factor-enhanced cancer selectivity and enhanced oncolytic potency. Mol Ther 2004; 9: 786-803.
-
(2004)
Mol Ther
, vol.9
, pp. 786-803
-
-
Liu, T.C.1
Hallden, G.2
Wang, Y.3
-
91
-
-
28844448965
-
Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus
-
Liu TC, Wang Y, Hallden G, et al. Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus. Gene Ther 2005; 12: 1333-46.
-
(2005)
Gene Ther
, vol.12
, pp. 1333-1346
-
-
Liu, T.C.1
Wang, Y.2
Hallden, G.3
-
92
-
-
1642430625
-
Functions and mechanisms of action of the adenovirus E3 proteins
-
Lichtenstein DL, Toth K, Doronin K, Tollefson AE, Wold WS. Functions and mechanisms of action of the adenovirus E3 proteins. Int Rev Immunol 2004; 23: 75-111.
-
(2004)
Int Rev Immunol
, vol.23
, pp. 75-111
-
-
Lichtenstein, D.L.1
Toth, K.2
Doronin, K.3
Tollefson, A.E.4
Wold, W.S.5
-
93
-
-
0242290921
-
E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models
-
Wang Y, Hallden G, Hill R, et al. E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models. Nat Biotechnol 2003; 21: 1328-35.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 1328-1335
-
-
Wang, Y.1
Hallden, G.2
Hill, R.3
-
94
-
-
17944371743
-
Gene delivery from the E3 region of replicating human adenovirus: Evaluation of the 6.7 K/gp19 K region
-
Hawkins LK, Johnson L, Bauzon M, et al. Gene delivery from the E3 region of replicating human adenovirus: evaluation of the 6.7 K/gp19 K region. Gene Ther 2001; 8: 1123-31.
-
(2001)
Gene Ther
, vol.8
, pp. 1123-1131
-
-
Hawkins, L.K.1
Johnson, L.2
Bauzon, M.3
-
95
-
-
0029872241
-
The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells
-
Tollefson AE, Scaria A, Hermiston TW, et al. The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells. J Virol 1996; 70: 2296-306.
-
(1996)
J Virol
, vol.70
, pp. 2296-2306
-
-
Tollefson, A.E.1
Scaria, A.2
Hermiston, T.W.3
-
96
-
-
0034086730
-
Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein
-
Doronin K, Toth K, Kuppuswamy M, et al. Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein. J Virol 2000; 74: 6147-55.
-
(2000)
J Virol
, vol.74
, pp. 6147-6155
-
-
Doronin, K.1
Toth, K.2
Kuppuswamy, M.3
-
97
-
-
0037455562
-
Overexpression of the ADP (E3-11.6K) protein increases cell lysis and spread of adenovirus
-
Doronin K, Toth K, Kuppuswamy M, et al. Overexpression of the ADP (E3-11.6K) protein increases cell lysis and spread of adenovirus. Virology 2003; 305: 378-87.
-
(2003)
Virology
, vol.305
, pp. 378-387
-
-
Doronin, K.1
Toth, K.2
Kuppuswamy, M.3
-
98
-
-
0034893340
-
Gene delivery from the E3 region of replicating human adenovirus: Evaluation of the E3B region
-
Hawkins LK, Hermiston T. Gene delivery from the E3 region of replicating human adenovirus: evaluation of the E3B region. Gene Ther 2001; 8: 1142-8.
-
(2001)
Gene Ther
, vol.8
, pp. 1142-1148
-
-
Hawkins, L.K.1
Hermiston, T.2
-
99
-
-
0034893340
-
Gene delivery from the E3 region of replicating human adenovirus: Evaluation of the ADP region
-
Hawkins LK, Hermiston TW. Gene delivery from the E3 region of replicating human adenovirus: evaluation of the ADP region. Gene Ther 2001; 8: 1132-41.
-
(2001)
Gene Ther
, vol.8
, pp. 1132-1141
-
-
Hawkins, L.K.1
Hermiston, T.W.2
-
100
-
-
0036413885
-
Late expression of p53 from a replicating adenovirus improves tumor cell killing and is more tumor cell specific than expression of the adenoviral death protein
-
Sauthoff H, Pipiya T, Heitner S, et al. Late expression of p53 from a replicating adenovirus improves tumor cell killing and is more tumor cell specific than expression of the adenoviral death protein. Hum Gene Ther 2002; 13: 1859-71.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1859-1871
-
-
Sauthoff, H.1
Pipiya, T.2
Heitner, S.3
-
101
-
-
0035956240
-
The role of adenovirus E4orf4 protein in viral replication and cell killing
-
Branton PE, Roopchand DE. The role of adenovirus E4orf4 protein in viral replication and cell killing. Oncogene 2001; 20: 7855-65.
-
(2001)
Oncogene
, vol.20
, pp. 7855-7865
-
-
Branton, P.E.1
Roopchand, D.E.2
-
102
-
-
32444433144
-
Genetic identification of adenovirus type 5 genes that influence viral spread
-
Subramanian T, Vijayalingam S, Chinnadurai G. Genetic identification of adenovirus type 5 genes that influence viral spread. J Virol 2006; 80: 2000-12.
-
(2006)
J Virol
, vol.80
, pp. 2000-2012
-
-
Subramanian, T.1
Vijayalingam, S.2
Chinnadurai, G.3
-
103
-
-
0041589480
-
E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer
-
Fukuda K, Abei M, Ugai H, et al. E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer. Cancer Res 2003; 63: 4434-40.
-
(2003)
Cancer Res
, vol.63
, pp. 4434-4440
-
-
Fukuda, K.1
Abei, M.2
Ugai, H.3
-
104
-
-
37349092322
-
Oncolytic virotherapy for prostate cancer by E1A, E1B mutant adenovirus
-
Satoh M, Wang H, Ishidoya S, et al. Oncolytic virotherapy for prostate cancer by E1A, E1B mutant adenovirus. Urology 2007; 70: 1243-8.
-
(2007)
Urology
, vol.70
, pp. 1243-1248
-
-
Satoh, M.1
Wang, H.2
Ishidoya, S.3
-
105
-
-
34249812369
-
E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers
-
Wakayama M, Abei M, Kawashima R, et al. E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers. Clin Cancer Res 2007; 13: 3043-50.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3043-3050
-
-
Wakayama, M.1
Abei, M.2
Kawashima, R.3
-
106
-
-
33748942284
-
Oncolytic viral therapy by bladder instillation using an E1A, E1B double-restricted adenovirus in an orthotopic bladder cancer model
-
Wang H, Satoh M, Abe H, et al. Oncolytic viral therapy by bladder instillation using an E1A, E1B double-restricted adenovirus in an orthotopic bladder cancer model. Urology 2006; 68: 674-81.
-
(2006)
Urology
, vol.68
, pp. 674-681
-
-
Wang, H.1
Satoh, M.2
Abe, H.3
-
107
-
-
34848856424
-
E1A- and E1B-Double mutant replicating adenovirus elicits enhanced oncolytic and antitumor effects
-
Kim J, Kim JH, Choi KJ, Kim PH, Yun CO. E1A- and E1B-Double mutant replicating adenovirus elicits enhanced oncolytic and antitumor effects. Hum Gene Ther 2007; 18: 773-86.
-
(2007)
Hum Gene Ther
, vol.18
, pp. 773-786
-
-
Kim, J.1
Kim, J.H.2
Choi, K.J.3
Kim, P.H.4
Yun, C.O.5
-
108
-
-
27944471015
-
Development of transcriptionally regulated oncolytic adenoviruses
-
Ko D, Hawkins L, Yu DC. Development of transcriptionally regulated oncolytic adenoviruses. Oncogene 2005; 24: 7763-74.
-
(2005)
Oncogene
, vol.24
, pp. 7763-7774
-
-
Ko, D.1
Hawkins, L.2
Yu, D.C.3
-
109
-
-
0030790684
-
Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
-
Rodriguez R, Schuur ER, Lim HY, et al. Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res 1997; 57: 2559-63.
-
(1997)
Cancer Res
, vol.57
, pp. 2559-2563
-
-
Rodriguez, R.1
Schuur, E.R.2
Lim, H.Y.3
-
110
-
-
27944486111
-
Oncolytic adenovirus that overproduces ADP and replicates selectively in tumors due to hTERT promoter-regulated E4 gene expression
-
Kuppuswamy M, Spencer JF, Doronin K, et al. Oncolytic adenovirus that overproduces ADP and replicates selectively in tumors due to hTERT promoter-regulated E4 gene expression. Gene Ther 2005; 12: 1608-17.
-
(2005)
Gene Ther
, vol.12
, pp. 1608-1617
-
-
Kuppuswamy, M.1
Spencer, J.F.2
Doronin, K.3
-
111
-
-
1642576131
-
Telomerase-specific replication-selective virotherapy for human cancer
-
Kawashima T, Kagawa S, Kobayashi N, et al. Telomerase-specific replication-selective virotherapy for human cancer. Clin Cancer Res 2004; 10: 285-92.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 285-292
-
-
Kawashima, T.1
Kagawa, S.2
Kobayashi, N.3
-
112
-
-
0035120593
-
Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway
-
Brunori M, Malerba M, Kashiwazaki H, Iggo R. Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway. J Virol 2001; 75: 2857-65.
-
(2001)
J Virol
, vol.75
, pp. 2857-2865
-
-
Brunori, M.1
Malerba, M.2
Kashiwazaki, H.3
Iggo, R.4
-
113
-
-
0035100867
-
Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy
-
Doronin K, Kuppuswamy M, Toth K, et al. Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy. J Virol 2001; 75: 3314-24.
-
(2001)
J Virol
, vol.75
, pp. 3314-3324
-
-
Doronin, K.1
Kuppuswamy, M.2
Toth, K.3
-
114
-
-
20144387357
-
Gene therapy for prostate cancer by controlling adenovirus E1a and E4 gene expression with PSES enhancer
-
Li X, Zhang YP, Kim HS, et al. Gene therapy for prostate cancer by controlling adenovirus E1a and E4 gene expression with PSES enhancer. Cancer Res 2005; 65: 1941-51.
-
(2005)
Cancer Res
, vol.65
, pp. 1941-1951
-
-
Li, X.1
Zhang, Y.P.2
Kim, H.S.3
-
115
-
-
33847390325
-
Telomerase-specific oncolytic virotherapy for human cancer with the hTERT promoter
-
Fujiwara T, Urata Y, Tanaka N. Telomerase-specific oncolytic virotherapy for human cancer with the hTERT promoter. Curr Cancer Drug Targets 2007; 7: 191-201.
-
(2007)
Curr Cancer Drug Targets
, vol.7
, pp. 191-201
-
-
Fujiwara, T.1
Urata, Y.2
Tanaka, N.3
-
116
-
-
4043135736
-
Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer
-
Ryan PC, Jakubczak JL, Stewart DA, et al. Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer. Cancer Gene Ther 2004; 11: 555-69.
-
(2004)
Cancer Gene Ther
, vol.11
, pp. 555-569
-
-
Ryan, P.C.1
Jakubczak, J.L.2
Stewart, D.A.3
-
117
-
-
0042674013
-
Telomerase-dependent oncolytic adenovirus for cancer treatment
-
Huang TG, Savontaus MJ, Shinozaki K, Sauter BV, Woo SL. Telomerase-dependent oncolytic adenovirus for cancer treatment. Gene Ther 2003; 10: 1241-7.
-
(2003)
Gene Ther
, vol.10
, pp. 1241-1247
-
-
Huang, T.G.1
Savontaus, M.J.2
Shinozaki, K.3
Sauter, B.V.4
Woo, S.L.5
-
118
-
-
20444470124
-
Survivin-responsive conditionally replicating adenovirus exhibits cancer-specific and efficient viral replication
-
Kamizono J, Nagano S, Murofushi Y, et al. Survivin-responsive conditionally replicating adenovirus exhibits cancer-specific and efficient viral replication. Cancer Res 2005; 65: 5284-91.
-
(2005)
Cancer Res
, vol.65
, pp. 5284-5291
-
-
Kamizono, J.1
Nagano, S.2
Murofushi, Y.3
-
119
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14: 1837-51.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
120
-
-
0036200352
-
Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway
-
Fuerer C, Iggo R. Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway. Gene Ther 2002; 9: 270-81.
-
(2002)
Gene Ther
, vol.9
, pp. 270-281
-
-
Fuerer, C.1
Iggo, R.2
-
121
-
-
0037509944
-
A novel hypoxia-inducible factor (HIF) activated oncolytic adenovirus for cancer therapy
-
Post DE, Van Meir EG. A novel hypoxia-inducible factor (HIF) activated oncolytic adenovirus for cancer therapy. Oncogene 2003; 22: 2065-72.
-
(2003)
Oncogene
, vol.22
, pp. 2065-2072
-
-
Post, D.E.1
Van Meir, E.G.2
-
122
-
-
7044233630
-
Oncolytic effects of adenovirus mutant capable of replicating in hypoxic and normoxic regions of solid tumor
-
Cho WK, Seong YR, Lee YH, et al. Oncolytic effects of adenovirus mutant capable of replicating in hypoxic and normoxic regions of solid tumor. Mol Ther 2004; 10: 938-49.
-
(2004)
Mol Ther
, vol.10
, pp. 938-949
-
-
Cho, W.K.1
Seong, Y.R.2
Lee, Y.H.3
-
123
-
-
20744442757
-
Effect of hypoxia on Ad5 infection, transgene expression and replication
-
Shen BH, Hermiston TW. Effect of hypoxia on Ad5 infection, transgene expression and replication. Gene Ther 2005; 12: 902-10.
-
(2005)
Gene Ther
, vol.12
, pp. 902-910
-
-
Shen, B.H.1
Hermiston, T.W.2
-
124
-
-
20744460916
-
Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression
-
Pipiya T, Sauthoff H, Huang YQ, et al. Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression. Gene Ther 2005; 12: 911-7.
-
(2005)
Gene Ther
, vol.12
, pp. 911-917
-
-
Pipiya, T.1
Sauthoff, H.2
Huang, Y.Q.3
-
125
-
-
0041911485
-
A novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replication
-
Fechner H, Wang X, Srour M, et al. A novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replication. Gene Ther 2003; 10: 1680-90.
-
(2003)
Gene Ther
, vol.10
, pp. 1680-1690
-
-
Fechner, H.1
Wang, X.2
Srour, M.3
-
126
-
-
0036129366
-
New tools for the construction of replication-competent adenoviral vectors with altered E1A regulation
-
Avvakumov N, Mymryk JS. New tools for the construction of replication-competent adenoviral vectors with altered E1A regulation. J Virol Methods 2002; 103: 41-9.
-
(2002)
J Virol Methods
, vol.103
, pp. 41-49
-
-
Avvakumov, N.1
Mymryk, J.S.2
-
127
-
-
0036169663
-
A system for small-molecule control of conditionally replication-competent adenoviral vectors
-
Chong H, Ruchatz A, Clackson T, Rivera VM, Vile RG. A system for small-molecule control of conditionally replication-competent adenoviral vectors. Mol Ther 2002; 5: 195-203.
-
(2002)
Mol Ther
, vol.5
, pp. 195-203
-
-
Chong, H.1
Ruchatz, A.2
Clackson, T.3
Rivera, V.M.4
Vile, R.G.5
-
128
-
-
0034692458
-
A novel, conditionally replicative adenovirus for the treatment of breast cancer that allows controlled replication of E1a-deleted adenoviral vectors
-
Hernandez-Alcoceba R, Pihalja M, Wicha MS, Clarke MF. A novel, conditionally replicative adenovirus for the treatment of breast cancer that allows controlled replication of E1a-deleted adenoviral vectors. Hum Gene Ther 2000; 11: 2009-24.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 2009-2024
-
-
Hernandez-Alcoceba, R.1
Pihalja, M.2
Wicha, M.S.3
Clarke, M.F.4
-
129
-
-
0036606008
-
A novel targeting modality to enhance adenoviral replication by vitamin D(3) in androgen-independent human prostate cancer cells and tumors
-
Hsieh CL, Yang L, Miao L, et al. A novel targeting modality to enhance adenoviral replication by vitamin D(3) in androgen-independent human prostate cancer cells and tumors. Cancer Res 2002; 62: 3084-92.
-
(2002)
Cancer Res
, vol.62
, pp. 3084-3092
-
-
Hsieh, C.L.1
Yang, L.2
Miao, L.3
-
130
-
-
0034881627
-
Replicating adenoviral vector-mediated transfer of a heat-inducible double suicide gene for gene therapy
-
Lee YJ, Galoforo SS, Battle P, et al. Replicating adenoviral vector-mediated transfer of a heat-inducible double suicide gene for gene therapy. Cancer Gene Ther 2001; 8: 397-404.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 397-404
-
-
Lee, Y.J.1
Galoforo, S.S.2
Battle, P.3
-
131
-
-
0036841845
-
TNFerade Biologic: Preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene
-
Rasmussen H, Rasmussen C, Lempicki M, et al. TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene. Cancer Gene Ther 2002; 9: 951-7.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 951-957
-
-
Rasmussen, H.1
Rasmussen, C.2
Lempicki, M.3
-
132
-
-
0034175969
-
Gene therapy: Designer promoters for tumour targeting
-
Nettelbeck DM, Jerome V, Muller R. Gene therapy: designer promoters for tumour targeting. Trends Genet 2000; 16: 174-81.
-
(2000)
Trends Genet
, vol.16
, pp. 174-181
-
-
Nettelbeck, D.M.1
Jerome, V.2
Muller, R.3
-
133
-
-
42449112872
-
Cellular genetic tools to control oncolytic adenoviruses for virotherapy of cancer
-
Nettelbeck DM. Cellular genetic tools to control oncolytic adenoviruses for virotherapy of cancer. J Mol Med 2008; 86: 363-77.
-
(2008)
J Mol Med
, vol.86
, pp. 363-377
-
-
Nettelbeck, D.M.1
-
134
-
-
0036399291
-
New oncolytic adenoviruses with hypoxia- and estrogen receptor-regulated replication
-
Hernandez-Alcoceba R, Pihalja M, Qian D, Clarke MF. New oncolytic adenoviruses with hypoxia- and estrogen receptor-regulated replication. Hum Gene Ther 2002; 13: 1737-50.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1737-1750
-
-
Hernandez-Alcoceba, R.1
Pihalja, M.2
Qian, D.3
Clarke, M.F.4
-
135
-
-
0037229427
-
Transcription initiation activity of adenovirus left-end sequence in adenovirus vectors with e1 deleted
-
Yamamoto M, Davydova J, Takayama K, Alemany R, Curiel DT. Transcription initiation activity of adenovirus left-end sequence in adenovirus vectors with e1 deleted. J Virol 2003; 77: 1633-7.
-
(2003)
J Virol
, vol.77
, pp. 1633-1637
-
-
Yamamoto, M.1
Davydova, J.2
Takayama, K.3
Alemany, R.4
Curiel, D.T.5
-
136
-
-
0038496739
-
A conditionally replicating adenovirus targeted to tumor cells through activated RAS/ PMAPK-selective mRNA stabilization
-
Ahmed A, Thompson J, Emiliusen L, et al. A conditionally replicating adenovirus targeted to tumor cells through activated RAS/ PMAPK-selective mRNA stabilization. Nat Biotechnol 2003; 21: 771-7.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 771-777
-
-
Ahmed, A.1
Thompson, J.2
Emiliusen, L.3
-
137
-
-
43049140850
-
Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control
-
Stoff-Khalili MA, Rivera AA, Nedeljkovic-Kurepa A, et al. Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control. Breast Cancer Res Treat 2008; 108: 43-55.
-
(2008)
Breast Cancer Res Treat
, vol.108
, pp. 43-55
-
-
Stoff-Khalili, M.A.1
Rivera, A.A.2
Nedeljkovic-Kurepa, A.3
-
138
-
-
0032481577
-
Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/ cytosine deaminase gene therapies
-
Aghi M, Kramm CM, Chou TC, Breakefield XO, Chiocca EA. Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/ cytosine deaminase gene therapies. J Natl Cancer Inst 1998; 90: 370-80.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 370-380
-
-
Aghi, M.1
Kramm, C.M.2
Chou, T.C.3
Breakefield, X.O.4
Chiocca, E.A.5
-
139
-
-
33746881714
-
Cancer gene therapy: Combination with radiation therapy and the role of bystander cell killing in the anti-tumor effect
-
Lumniczky K, Safrany G. Cancer gene therapy: combination with radiation therapy and the role of bystander cell killing in the anti-tumor effect. Pathol Oncol Res 2006; 12: 118-24.
-
(2006)
Pathol Oncol Res
, vol.12
, pp. 118-124
-
-
Lumniczky, K.1
Safrany, G.2
-
140
-
-
33845409424
-
Viral vectors for gene-directed enzyme prodrug therapy
-
Schepelmann S, Springer CJ. Viral vectors for gene-directed enzyme prodrug therapy. Curr Gene Ther 2006; 6: 647-70.
-
(2006)
Curr Gene Ther
, vol.6
, pp. 647-670
-
-
Schepelmann, S.1
Springer, C.J.2
-
141
-
-
20344370056
-
Antitumor effects and radiosensitization of cytosine deaminase and thymidine kinase fusion suicide gene on colorectal carcinoma cells
-
Wu DH, Liu L, Chen LH. Antitumor effects and radiosensitization of cytosine deaminase and thymidine kinase fusion suicide gene on colorectal carcinoma cells. World J Gastroenterol 2005; 11: 3051-5.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3051-3055
-
-
Wu, D.H.1
Liu, L.2
Chen, L.H.3
-
142
-
-
0030666029
-
Pronounced antitumor effects and tumor radiosensitization of double suicide gene therapy
-
Rogulski KR, Zhang K, Kolozsvary A, Kim JH, Freytag SO. Pronounced antitumor effects and tumor radiosensitization of double suicide gene therapy. Clin Cancer Res 1997; 3: 2081-8.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2081-2088
-
-
Rogulski, K.R.1
Zhang, K.2
Kolozsvary, A.3
Kim, J.H.4
Freytag, S.O.5
-
143
-
-
10744227813
-
Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer
-
Freytag SO, Stricker H, Pegg J, et al. Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer. Cancer Res 2003; 63: 7497-506.
-
(2003)
Cancer Res
, vol.63
, pp. 7497-7506
-
-
Freytag, S.O.1
Stricker, H.2
Pegg, J.3
-
144
-
-
10844256740
-
Tumor-specific intravenous gene delivery using oncolytic adenoviruses
-
Zhan J, Gao Y, Wang W, et al. Tumor-specific intravenous gene delivery using oncolytic adenoviruses. Cancer Gene Ther 2005; 12: 19-25.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 19-25
-
-
Zhan, J.1
Gao, Y.2
Wang, W.3
-
145
-
-
33645509483
-
A novel mechanism of synergistic cytotoxicity with 5-fluorocytosine and ganciclovir in double suicide gene therapy
-
Boucher PD, Im MM, Freytag SO, Shewach DS. A novel mechanism of synergistic cytotoxicity with 5-fluorocytosine and ganciclovir in double suicide gene therapy. Cancer Res 2006; 66: 3230-7.
-
(2006)
Cancer Res
, vol.66
, pp. 3230-3237
-
-
Boucher, P.D.1
Im, M.M.2
Freytag, S.O.3
Shewach, D.S.4
-
146
-
-
0037062951
-
RNA interference
-
Hannon GJ. RNA interference. Nature 2002; 418: 244-51.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
150
-
-
10744221455
-
Adenoviral vectors expressing siRNAs for discovery and validation of gene function
-
Arts GJ, Langemeijer E, Tissingh R, et al. Adenoviral vectors expressing siRNAs for discovery and validation of gene function. Genome Res 2003; 13: 2325-32.
-
(2003)
Genome Res
, vol.13
, pp. 2325-2332
-
-
Arts, G.J.1
Langemeijer, E.2
Tissingh, R.3
-
151
-
-
0141991324
-
Specific gene inhibition by adenovirus-mediated expression of small interfering RNA
-
Zhao LJ, Jian H, Zhu H. Specific gene inhibition by adenovirus-mediated expression of small interfering RNA. Gene 2003; 316: 137-41.
-
(2003)
Gene
, vol.316
, pp. 137-141
-
-
Zhao, L.J.1
Jian, H.2
Zhu, H.3
-
152
-
-
0037468660
-
Gene silencing by adenovirus-delivered siRNA
-
Shen C, Buck AK, Liu X, Winkler M, Reske SN. Gene silencing by adenovirus-delivered siRNA. FEBS Lett 2003; 539: 111-4.
-
(2003)
FEBS Lett
, vol.539
, pp. 111-114
-
-
Shen, C.1
Buck, A.K.2
Liu, X.3
Winkler, M.4
Reske, S.N.5
-
153
-
-
42149120089
-
Short hairpin RNA-expressing oncolytic adenovirus-mediated inhibition of IL-8: Effects on antiangio-genesis and tumor growth inhibition
-
Yoo JY, Kim JH, Kim J, et al. Short hairpin RNA-expressing oncolytic adenovirus-mediated inhibition of IL-8: effects on antiangio-genesis and tumor growth inhibition. Gene Ther 2008; 15: 635-51.
-
(2008)
Gene Ther
, vol.15
, pp. 635-651
-
-
Yoo, J.Y.1
Kim, J.H.2
Kim, J.3
-
154
-
-
35148820704
-
Overcoming the classical multidrug resistance phenotype by adenoviral delivery of anti-MDR1 short hairpin RNAs and ribozymes
-
Kaszubiak A, Holm PS, Lage H. Overcoming the classical multidrug resistance phenotype by adenoviral delivery of anti-MDR1 short hairpin RNAs and ribozymes. Int J Oncol 2007; 31: 419-30.
-
(2007)
Int J Oncol
, vol.31
, pp. 419-430
-
-
Kaszubiak, A.1
Holm, P.S.2
Lage, H.3
-
155
-
-
34548083069
-
Adenovirus-mediated small hairpin RNA targeting Bcl-XL as therapy for colon cancer
-
Zhu H, Zhu Y, Hu J, et al. Adenovirus-mediated small hairpin RNA targeting Bcl-XL as therapy for colon cancer. Int J Cancer 2007; 121: 1366-72.
-
(2007)
Int J Cancer
, vol.121
, pp. 1366-1372
-
-
Zhu, H.1
Zhu, Y.2
Hu, J.3
-
156
-
-
33749569829
-
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice
-
Chetty C, Bhoopathi P, Joseph P, et al. Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice. Mol Cancer Ther 2006; 5: 2289-99.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2289-2299
-
-
Chetty, C.1
Bhoopathi, P.2
Joseph, P.3
-
157
-
-
4644293454
-
Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells
-
Carette JE, Overmeer RM, Schagen FH, et al. Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells. Cancer Res 2004; 64: 2663-7.
-
(2004)
Cancer Res
, vol.64
, pp. 2663-2667
-
-
Carette, J.E.1
Overmeer, R.M.2
Schagen, F.H.3
-
158
-
-
33750321708
-
Antitumor activity of an oncolytic adenovirus-delivered oncogene small interfering RNA
-
Zhang YA, Nemunaitis J, Samuel SK, et al. Antitumor activity of an oncolytic adenovirus-delivered oncogene small interfering RNA. Cancer Res 2006; 66: 9736-43.
-
(2006)
Cancer Res
, vol.66
, pp. 9736-9743
-
-
Zhang, Y.A.1
Nemunaitis, J.2
Samuel, S.K.3
-
159
-
-
33846334835
-
VEGF-specific short hairpin RNA-expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth
-
Yoo JY, Kim JH, Kwon YG, et al. VEGF-specific short hairpin RNA-expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth. Mol Ther 2007; 15: 295-302.
-
(2007)
Mol Ther
, vol.15
, pp. 295-302
-
-
Yoo, J.Y.1
Kim, J.H.2
Kwon, Y.G.3
-
160
-
-
40949151900
-
Oncolytic adenovirus-mediated shRNA against Apollon inhibits tumor cell growth and enhances antitumor effect of 5-fluorouracil
-
Chu L, Gu J, Sun L, et al. Oncolytic adenovirus-mediated shRNA against Apollon inhibits tumor cell growth and enhances antitumor effect of 5-fluorouracil. Gene Ther 2008; 15: 484-94.
-
(2008)
Gene Ther
, vol.15
, pp. 484-494
-
-
Chu, L.1
Gu, J.2
Sun, L.3
-
161
-
-
22544463666
-
Suppression of RNA interference by adenovirus virus-associated RNA
-
Andersson MG, Haasnoot PC, Xu N, et al. Suppression of RNA interference by adenovirus virus-associated RNA. J Virol 2005; 79: 9556-65.
-
(2005)
J Virol
, vol.79
, pp. 9556-9565
-
-
Andersson, M.G.1
Haasnoot, P.C.2
Xu, N.3
-
162
-
-
31144451840
-
Adenovirus virus-associated RNA is processed to functional interfering RNAs involved in virus production
-
Aparicio O, Razquin N, Zaratiegui M, Narvaiza I, Fortes P. Adenovirus virus-associated RNA is processed to functional interfering RNAs involved in virus production. J Virol 2006; 80: 1376-84.
-
(2006)
J Virol
, vol.80
, pp. 1376-1384
-
-
Aparicio, O.1
Razquin, N.2
Zaratiegui, M.3
Narvaiza, I.4
Fortes, P.5
-
163
-
-
0025141337
-
What is the evidence that tumors are angiogenesis dependent?
-
Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990; 82: 4-6.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 4-6
-
-
Folkman, J.1
-
164
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407: 249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
165
-
-
0030937456
-
Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth
-
Tanaka T, Manome Y, Wen P, Kufe DW, Fine HA. Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth. Nat Med 1997; 3: 437-42.
-
(1997)
Nat Med
, vol.3
, pp. 437-442
-
-
Tanaka, T.1
Manome, Y.2
Wen, P.3
Kufe, D.W.4
Fine, H.A.5
-
166
-
-
13144254247
-
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
-
Lin P, Buxton JA, Acheson A, et al. Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. Proc Natl Acad Sci USA 1998; 95: 8829-34.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8829-8834
-
-
Lin, P.1
Buxton, J.A.2
Acheson, A.3
-
167
-
-
34248582785
-
Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth
-
Cao Y, Sonveaux P, Liu S, et al. Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth. Cancer Res 2007; 67: 3835-44.
-
(2007)
Cancer Res
, vol.67
, pp. 3835-3844
-
-
Cao, Y.1
Sonveaux, P.2
Liu, S.3
-
168
-
-
7344262560
-
Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice
-
Li H, Lu H, Griscelli F, et al. Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice. Gene Ther 1998; 5: 1105-13.
-
(1998)
Gene Ther
, vol.5
, pp. 1105-1113
-
-
Li, H.1
Lu, H.2
Griscelli, F.3
-
169
-
-
0034654555
-
Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice
-
Feldman AL, Restifo NP, Alexander HR, et al. Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice. Cancer Res 2000; 60: 1503-6.
-
(2000)
Cancer Res
, vol.60
, pp. 1503-1506
-
-
Feldman, A.L.1
Restifo, N.P.2
Alexander, H.R.3
-
170
-
-
0036839310
-
Kallistatin is a new inhibitor of angiogenesis and tumor growth
-
Miao RQ, Agata J, Chao L, Chao J. Kallistatin is a new inhibitor of angiogenesis and tumor growth. Blood 2002; 100: 3245-52.
-
(2002)
Blood
, vol.100
, pp. 3245-3252
-
-
Miao, R.Q.1
Agata, J.2
Chao, L.3
Chao, J.4
-
171
-
-
2442685367
-
Viral vector-mediated transduction of a modified thrombospondin-2 cDNA inhibits tumor growth and angiogenesis
-
Hahn W, Ho SH, Jeong JG, et al. Viral vector-mediated transduction of a modified thrombospondin-2 cDNA inhibits tumor growth and angiogenesis. Gene Ther 2004; 11: 739-45.
-
(2004)
Gene Ther
, vol.11
, pp. 739-745
-
-
Hahn, W.1
Ho, S.H.2
Jeong, J.G.3
-
172
-
-
33847276456
-
Adenovirus-mediated interferon-beta gene transfer inhibits angiogenesis in and progression of orthotopic tumors of human prostate cancer cells in nude mice
-
Lee J, Wang A, Hu Q, Lu S, Dong Z. Adenovirus-mediated interferon-beta gene transfer inhibits angiogenesis in and progression of orthotopic tumors of human prostate cancer cells in nude mice. Int J Oncol 2006; 29: 1405-12.
-
(2006)
Int J Oncol
, vol.29
, pp. 1405-1412
-
-
Lee, J.1
Wang, A.2
Hu, Q.3
Lu, S.4
Dong, Z.5
-
173
-
-
0036171069
-
Targeting angiogenesis and HGF function using an adenoviral vector expressing the HGF antagonist NK4 for cancer therapy
-
Maemondo M, Narumi K, Saijo Y, et al. Targeting angiogenesis and HGF function using an adenoviral vector expressing the HGF antagonist NK4 for cancer therapy. Mol Ther 2002; 5: 177-85.
-
(2002)
Mol Ther
, vol.5
, pp. 177-185
-
-
Maemondo, M.1
Narumi, K.2
Saijo, Y.3
-
174
-
-
0033855629
-
Failure of cancer vaccines: The significant limitations of this approach to immunotherapy
-
Bodey B, Bodey B, Jr, Siegel SE, Kaiser HE. Failure of cancer vaccines: the significant limitations of this approach to immunotherapy. Anticancer Res 2000; 20: 2665-76.
-
(2000)
Anticancer Res
, vol.20
, pp. 2665-2676
-
-
Bodey, B.1
Bodey Jr, B.2
Siegel, S.E.3
Kaiser, H.E.4
-
175
-
-
7444252305
-
On the road to a tumor cell vaccine: 20 years of cellular immunotherapy
-
Yannelli JR, Wroblewski JM. On the road to a tumor cell vaccine: 20 years of cellular immunotherapy. Vaccine 2004; 23: 97-113.
-
(2004)
Vaccine
, vol.23
, pp. 97-113
-
-
Yannelli, J.R.1
Wroblewski, J.M.2
-
176
-
-
0041411313
-
The Fas/Fas ligand system and cancer: Immune privilege and apoptosis
-
Abrahams VM, Kamsteeg M, Mor G. The Fas/Fas ligand system and cancer: immune privilege and apoptosis. Mol Biotechnol 2003; 25: 19-30.
-
(2003)
Mol Biotechnol
, vol.25
, pp. 19-30
-
-
Abrahams, V.M.1
Kamsteeg, M.2
Mor, G.3
-
177
-
-
3042844293
-
Cancer immunotherapy: A treatment for the masses
-
Blattman JN, Greenberg PD. Cancer immunotherapy: a treatment for the masses. Science 2004; 305: 200-5.
-
(2004)
Science
, vol.305
, pp. 200-205
-
-
Blattman, J.N.1
Greenberg, P.D.2
-
178
-
-
32944474058
-
Effective cancer therapy through immunomodulation
-
Waldmann TA. Effective cancer therapy through immunomodulation. Annu Rev Med 2006; 57: 65-81.
-
(2006)
Annu Rev Med
, vol.57
, pp. 65-81
-
-
Waldmann, T.A.1
-
179
-
-
0034010642
-
Interferon-gamma in the first-line therapy of ovarian cancer: A randomized phase III trial
-
Windbichler GH, Hausmaninger H, Stummvoll W, et al. Interferon-gamma in the first-line therapy of ovarian cancer: a randomized phase III trial. Br J Cancer 2000; 82: 1138-44.
-
(2000)
Br J Cancer
, vol.82
, pp. 1138-1144
-
-
Windbichler, G.H.1
Hausmaninger, H.2
Stummvoll, W.3
-
180
-
-
34548052428
-
Cytokine-based immunotherapy for advanced kidney cancer: Past results and future perspectives in the era of molecularly targeted agents
-
Porta C, Paglino C, Imarisio I, Bonomi L. Cytokine-based immunotherapy for advanced kidney cancer: past results and future perspectives in the era of molecularly targeted agents. Sci World J 2007; 7: 837-49.
-
(2007)
Sci World J
, vol.7
, pp. 837-849
-
-
Porta, C.1
Paglino, C.2
Imarisio, I.3
Bonomi, L.4
-
181
-
-
0025981003
-
The role of interleukin-2 in cancer immunotherapy
-
Eberlein TJ, Schoof DD. The role of interleukin-2 in cancer immunotherapy. Compr Ther 1991; 17: 49-56.
-
(1991)
Compr Ther
, vol.17
, pp. 49-56
-
-
Eberlein, T.J.1
Schoof, D.D.2
-
182
-
-
0029086344
-
Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model
-
Addison CL, Braciak T, Ralston R, et al. Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model. Proc Natl Acad Sci USA 1995; 92: 8522-6.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8522-8526
-
-
Addison, C.L.1
Braciak, T.2
Ralston, R.3
-
183
-
-
0002325617
-
Interleukin 12: Basic biology and potential applications in cancer treatment
-
Robertson MJ, Ritz J. Interleukin 12: basic biology and potential applications in cancer treatment. Oncologist 1996; 1: 88-97.
-
(1996)
Oncologist
, vol.1
, pp. 88-97
-
-
Robertson, M.J.1
Ritz, J.2
-
184
-
-
0029848051
-
Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12
-
Bramson JL, Hitt M, Addison CL, et al. Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12. Hum Gene Ther 1996; 7: 1995-2002.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1995-2002
-
-
Bramson, J.L.1
Hitt, M.2
Addison, C.L.3
-
185
-
-
0032609944
-
Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12
-
Gambotto A, Tuting T, McVey DL, et al. Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12. Cancer Gene Ther 1999; 6: 45-53.
-
(1999)
Cancer Gene Ther
, vol.6
, pp. 45-53
-
-
Gambotto, A.1
Tuting, T.2
McVey, D.L.3
-
186
-
-
2942590859
-
Adenovirus-mediated interleukin-18 mutant in vivo gene transfer inhibits tumor growth through the induction of T cell immunity and activation of natural killer cell cytotoxicity
-
Hwang KS, Cho WK, Yoo J, et al. Adenovirus-mediated interleukin-18 mutant in vivo gene transfer inhibits tumor growth through the induction of T cell immunity and activation of natural killer cell cytotoxicity. Cancer Gene Ther 2004; 11: 397-407.
-
(2004)
Cancer Gene Ther
, vol.11
, pp. 397-407
-
-
Hwang, K.S.1
Cho, W.K.2
Yoo, J.3
-
187
-
-
0030940081
-
The anti-human tumor effect and generation of human cytotoxic T cells in SCID mice given human peripheral blood lymphocytes by the in vivo transfer of the Interleukin-6 gene using adenovirus vector
-
Tanaka F, Abe M, Akiyoshi T, et al. The anti-human tumor effect and generation of human cytotoxic T cells in SCID mice given human peripheral blood lymphocytes by the in vivo transfer of the Interleukin-6 gene using adenovirus vector. Cancer Res 1997; 57: 1335-43.
-
(1997)
Cancer Res
, vol.57
, pp. 1335-1343
-
-
Tanaka, F.1
Abe, M.2
Akiyoshi, T.3
-
188
-
-
0035125085
-
Antitumor activity of recombinant adenoviral vectors expressing murine IFN-alpha in mice injected with metastatic IFN-resistant tumor cells
-
Santodonato L, Ferrantini M, Palombo F, et al. Antitumor activity of recombinant adenoviral vectors expressing murine IFN-alpha in mice injected with metastatic IFN-resistant tumor cells. Cancer Gene Ther 2001; 8: 63-72.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 63-72
-
-
Santodonato, L.1
Ferrantini, M.2
Palombo, F.3
-
189
-
-
0036664630
-
Analysis of the immunologic response generated by Ad.IFN-beta during successful intraperitoneal tumor gene therapy
-
Odaka M, Wiewrodt R, DeLong P, et al. Analysis of the immunologic response generated by Ad.IFN-beta during successful intraperitoneal tumor gene therapy. Mol Ther 2002; 6: 210-8.
-
(2002)
Mol Ther
, vol.6
, pp. 210-218
-
-
Odaka, M.1
Wiewrodt, R.2
DeLong, P.3
-
190
-
-
0037385454
-
A phase I trial of immunotherapy with intratumoral adenovirus-interferongamma (TG1041) in patients with malignant melanoma
-
Khorana AA, Rosenblatt JD, Sahasrabudhe DM, et al. A phase I trial of immunotherapy with intratumoral adenovirus-interferongamma (TG1041) in patients with malignant melanoma. Cancer Gene Ther 2003; 10: 251-9.
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 251-259
-
-
Khorana, A.A.1
Rosenblatt, J.D.2
Sahasrabudhe, D.M.3
-
191
-
-
0032955729
-
Adenovirus-mediated TNF-alpha gene transfer induces significant tumor regression in mice
-
Wright P, Braun R, Babiuk L, et al. Adenovirus-mediated TNF-alpha gene transfer induces significant tumor regression in mice. Cancer Biother Radiopharm 1999; 14: 49-57.
-
(1999)
Cancer Biother Radiopharm
, vol.14
, pp. 49-57
-
-
Wright, P.1
Braun, R.2
Babiuk, L.3
-
192
-
-
0031759989
-
Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors
-
Addison CL, Bramson JL, Hitt MM, et al. Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors. Gene Ther 1998; 5: 1400-9.
-
(1998)
Gene Ther
, vol.5
, pp. 1400-1409
-
-
Addison, C.L.1
Bramson, J.L.2
Hitt, M.M.3
-
193
-
-
0033586324
-
Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models
-
Emtage PC, Wan Y, Hitt M, et al. Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models. Hum Gene Ther 1999; 10: 697-709.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 697-709
-
-
Emtage, P.C.1
Wan, Y.2
Hitt, M.3
-
194
-
-
0036271492
-
Intratumoral coinjection of two adenoviral vectors expressing functional interleukin-18 and inducible protein-10, respectively, synergizes to facilitate regression of established tumors
-
Liu Y, Huang H, Saxena A, Xiang J. Intratumoral coinjection of two adenoviral vectors expressing functional interleukin-18 and inducible protein-10, respectively, synergizes to facilitate regression of established tumors. Cancer Gene Ther 2002; 9: 533-42.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 533-542
-
-
Liu, Y.1
Huang, H.2
Saxena, A.3
Xiang, J.4
-
195
-
-
0034653833
-
Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-gamma-inducible protein-10 and another encoding IL-12, results in marked antitumoral synergy
-
Narvaiza I, Mazzolini G, Barajas M, et al. Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-gamma-inducible protein-10 and another encoding IL-12, results in marked antitumoral synergy. J Immunol 2000; 164: 3112-22.
-
(2000)
J Immunol
, vol.164
, pp. 3112-3122
-
-
Narvaiza, I.1
Mazzolini, G.2
Barajas, M.3
-
197
-
-
0034923709
-
Replication-deficient adenovirus-mediated transfer of B7-1 (CD80) cDNA induces anti-tumour immunity in isolated human lung cancer
-
Iwakami SI, Setoguchi Y, Saijo Y, Azuma M, Fukuchi Y. Replication-deficient adenovirus-mediated transfer of B7-1 (CD80) cDNA induces anti-tumour immunity in isolated human lung cancer. Respirology 2001; 6: 135-44.
-
(2001)
Respirology
, vol.6
, pp. 135-144
-
-
Iwakami, S.I.1
Setoguchi, Y.2
Saijo, Y.3
Azuma, M.4
Fukuchi, Y.5
-
198
-
-
0031828150
-
Adenoviral delivery of B7-1 (CD80) increases the immunogenicity of human ovarian and cervical carcinoma cells
-
Gilligan MG, Knox P, Weedon S, et al. Adenoviral delivery of B7-1 (CD80) increases the immunogenicity of human ovarian and cervical carcinoma cells. Gene Ther 1998; 5: 965-74.
-
(1998)
Gene Ther
, vol.5
, pp. 965-974
-
-
Gilligan, M.G.1
Knox, P.2
Weedon, S.3
-
199
-
-
0030931602
-
Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression
-
Putzer BM, Hitt M, Muller WJ, et al. Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. Proc Natl Acad Sci USA 1997; 94: 10889-94.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10889-10894
-
-
Putzer, B.M.1
Hitt, M.2
Muller, W.J.3
-
200
-
-
33745191473
-
Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect
-
Choi KJ, Kim JH, Lee YS, et al. Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect. Gene Ther 2006; 13: 1010-20.
-
(2006)
Gene Ther
, vol.13
, pp. 1010-1020
-
-
Choi, K.J.1
Kim, J.H.2
Lee, Y.S.3
-
201
-
-
33750332951
-
Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model
-
Lee YS, Kim JH, Choi KJ, et al. Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model. Clin Cancer Res 2006; 12: 5859-68.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5859-5868
-
-
Lee, Y.S.1
Kim, J.H.2
Choi, K.J.3
-
202
-
-
0033587141
-
Anti-tumor immunity induced by in vivo adenovirus vector-mediated expression of CD40 ligand in tumor cells
-
Kikuchi T, Crystal RG. Anti-tumor immunity induced by in vivo adenovirus vector-mediated expression of CD40 ligand in tumor cells. Hum Gene Ther 1999; 10: 1375-87.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 1375-1387
-
-
Kikuchi, T.1
Crystal, R.G.2
-
203
-
-
2442667692
-
Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor Microenvironment
-
Loskog A, Dzojic H, Vikman S, et al. Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor Microenvironment. J Immunol 2004; 172: 7200-5.
-
(2004)
J Immunol
, vol.172
, pp. 7200-7205
-
-
Loskog, A.1
Dzojic, H.2
Vikman, S.3
-
204
-
-
36248951128
-
Co-stimulation with 4-1BB ligand allows extended T-cell proliferation, synergizes with CD80/CD86 and can reactivate anergic T cells
-
Habib-Agahi M, Phan TT, Searle PF. Co-stimulation with 4-1BB ligand allows extended T-cell proliferation, synergizes with CD80/CD86 and can reactivate anergic T cells. Int Immunol 2007; 19: 1383-94.
-
(2007)
Int Immunol
, vol.19
, pp. 1383-1394
-
-
Habib-Agahi, M.1
Phan, T.T.2
Searle, P.F.3
-
205
-
-
27144497304
-
The systemic administration of Ig-4-1BB ligand in combination with IL-12 gene transfer eradicates hepatic colon carcinoma
-
Xu DP, Sauter BV, Huang TG, et al. The systemic administration of Ig-4-1BB ligand in combination with IL-12 gene transfer eradicates hepatic colon carcinoma. Gene Ther 2005; 12: 1526-33.
-
(2005)
Gene Ther
, vol.12
, pp. 1526-1533
-
-
Xu, D.P.1
Sauter, B.V.2
Huang, T.G.3
-
206
-
-
0034616629
-
Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand: Long- term remission of liver metastases in a mouse model
-
Martinet O, Ermekova V, Qiao JQ, et al. Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand: long- term remission of liver metastases in a mouse model. J Natl Cancer Inst 2000; 92: 931-6.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 931-936
-
-
Martinet, O.1
Ermekova, V.2
Qiao, J.Q.3
-
207
-
-
0037295579
-
A novel adenovirus expressing human 4-1BB ligand enhances antitumor immunity
-
Yoshida H, Katayose Y, Unno M, et al. A novel adenovirus expressing human 4-1BB ligand enhances antitumor immunity. Cancer Immunol Immunother 2003; 52: 97-106.
-
(2003)
Cancer Immunol Immunother
, vol.52
, pp. 97-106
-
-
Yoshida, H.1
Katayose, Y.2
Unno, M.3
-
208
-
-
33645086129
-
Combinational adenovirus-mediated gene therapy and dendritic cell vaccine in combating well-established tumors
-
Xia D, Moyana T, Xiang J. Combinational adenovirus-mediated gene therapy and dendritic cell vaccine in combating well-established tumors. Cell Res 2006; 16: 241-59.
-
(2006)
Cell Res
, vol.16
, pp. 241-259
-
-
Xia, D.1
Moyana, T.2
Xiang, J.3
-
209
-
-
42649132048
-
Factors involved in the maturation of murine dendritic cells transduced with adenoviral vector variants
-
Kanagawa N, Koretomo R, Murakami S, et al. Factors involved in the maturation of murine dendritic cells transduced with adenoviral vector variants. Virology 2008; 374: 411-20.
-
(2008)
Virology
, vol.374
, pp. 411-420
-
-
Kanagawa, N.1
Koretomo, R.2
Murakami, S.3
-
210
-
-
0033843263
-
Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cells
-
Geutskens SB, van der Eb MM, Plomp AC, et al. Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cells. Gene Ther 2000; 7: 1410-6.
-
(2000)
Gene Ther
, vol.7
, pp. 1410-1416
-
-
Geutskens, S.B.1
van der Eb, M.M.2
Plomp, A.C.3
-
211
-
-
0033113957
-
Murine dendritic cells transduced with an adenoviral vector expressing a defined tumor antigen can overcome anti-adenovirus neutralizing immunity and induce effective tumor regression
-
Wan Y, Emtage P, Foley R, Carter R, Gauldie J. Murine dendritic cells transduced with an adenoviral vector expressing a defined tumor antigen can overcome anti-adenovirus neutralizing immunity and induce effective tumor regression. Int J Oncol 1999; 14: 771-6.
-
(1999)
Int J Oncol
, vol.14
, pp. 771-776
-
-
Wan, Y.1
Emtage, P.2
Foley, R.3
Carter, R.4
Gauldie, J.5
-
212
-
-
7444247986
-
Vaccination by genetically modified dendritic cells expressing a truncated neu oncogene prevents development of breast cancer in transgenic mice
-
Sakai Y, Morrison BJ, Burke JD, et al. Vaccination by genetically modified dendritic cells expressing a truncated neu oncogene prevents development of breast cancer in transgenic mice. Cancer Res 2004; 64: 8022-8.
-
(2004)
Cancer Res
, vol.64
, pp. 8022-8028
-
-
Sakai, Y.1
Morrison, B.J.2
Burke, J.D.3
-
213
-
-
33750837242
-
In vitro anti-tumor immune response induced by dendritic cells transfected with hTERT recombinant adenovirus
-
Chen L, Liang GP, Tang XD, et al. In vitro anti-tumor immune response induced by dendritic cells transfected with hTERT recombinant adenovirus. Biochem Biophys Res Commun 2006; 351: 927-34.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 927-934
-
-
Chen, L.1
Liang, G.P.2
Tang, X.D.3
-
214
-
-
27544510429
-
Adenovirus as vehicle for anticancer genetic immunotherapy
-
Gallo P, Dharmapuri S, Cipriani B, Monaci P. Adenovirus as vehicle for anticancer genetic immunotherapy. Gene Ther 2005; 12 Suppl 1: S84-91.
-
(2005)
Gene Ther
, vol.12
, Issue.SUPPL. 1
-
-
Gallo, P.1
Dharmapuri, S.2
Cipriani, B.3
Monaci, P.4
-
215
-
-
0032844949
-
Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas
-
Melero I, Duarte M, Ruiz J, et al. Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas. Gene Ther 1999; 6: 1779-84.
-
(1999)
Gene Ther
, vol.6
, pp. 1779-1784
-
-
Melero, I.1
Duarte, M.2
Ruiz, J.3
-
216
-
-
0036170543
-
Adenovirus-mediated CD40 ligand gene-engineered dendritic cells elicit enhanced CD8(+) cytotoxic T-cell activation and antitumor immunity
-
Liu Y, Zhang X, Zhang W, et al. Adenovirus-mediated CD40 ligand gene-engineered dendritic cells elicit enhanced CD8(+) cytotoxic T-cell activation and antitumor immunity. Cancer Gene Ther 2002; 9: 202-8.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 202-208
-
-
Liu, Y.1
Zhang, X.2
Zhang, W.3
-
217
-
-
38549143194
-
Gene transfer of CD40-ligand to dendritic cells stimulates interferon-gamma production to induce growth arrest and apoptosis of tumor cells
-
Tomihara K, Kato K, Masuta Y, et al. Gene transfer of CD40-ligand to dendritic cells stimulates interferon-gamma production to induce growth arrest and apoptosis of tumor cells. Gene Ther 2008; 15: 203-13.
-
(2008)
Gene Ther
, vol.15
, pp. 203-213
-
-
Tomihara, K.1
Kato, K.2
Masuta, Y.3
-
218
-
-
35848940280
-
Benefits of gene transduction of granulocyte macrophage colony-stimulating factor in cancer vaccine using genetically modified dendritic cells
-
Ojima T, Iwahashi M, Nakamura M, et al. Benefits of gene transduction of granulocyte macrophage colony-stimulating factor in cancer vaccine using genetically modified dendritic cells. Int J Oncol 2007; 31: 931-9.
-
(2007)
Int J Oncol
, vol.31
, pp. 931-939
-
-
Ojima, T.1
Iwahashi, M.2
Nakamura, M.3
-
219
-
-
34247178955
-
Alpha-fetoprotein and interleukin-18 gene-modified dendritic cells effectively stimulate specific type-1 CD4- and CD8-mediated T-Cell response from hepatocellular carcinoma patients in vitro
-
Cao DY, Yang JY, Dou KF, Ma LY, Teng ZH. Alpha-fetoprotein and interleukin-18 gene-modified dendritic cells effectively stimulate specific type-1 CD4- and CD8-mediated T-Cell response from hepatocellular carcinoma patients in vitro. Hum Immunol 2007; 68: 334-41.
-
(2007)
Hum Immunol
, vol.68
, pp. 334-341
-
-
Cao, D.Y.1
Yang, J.Y.2
Dou, K.F.3
Ma, L.Y.4
Teng, Z.H.5
-
220
-
-
0034816695
-
Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors
-
Okada N, Tsukada Y, Nakagawa S, et al. Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors. Biochem Biophys Res Commun 2001; 282: 173-9.
-
(2001)
Biochem Biophys Res Commun
, vol.282
, pp. 173-179
-
-
Okada, N.1
Tsukada, Y.2
Nakagawa, S.3
-
221
-
-
12444262198
-
Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors
-
Okada N, Masunaga Y, Okada Y, et al. Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors. Cancer Gene Ther 2003; 10: 421-31.
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 421-431
-
-
Okada, N.1
Masunaga, Y.2
Okada, Y.3
-
222
-
-
0036710714
-
The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells
-
Kim M, Zinn KR, Barnett BG, et al. The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells. Eur J Cancer 2002; 38: 1917-26.
-
(2002)
Eur J Cancer
, vol.38
, pp. 1917-1926
-
-
Kim, M.1
Zinn, K.R.2
Barnett, B.G.3
-
223
-
-
0035077806
-
Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies
-
Fisher KD, Stallwood Y, Green NK, et al. Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies. Gene Ther 2001; 8: 341-8.
-
(2001)
Gene Ther
, vol.8
, pp. 341-348
-
-
Fisher, K.D.1
Stallwood, Y.2
Green, N.K.3
-
224
-
-
0034691085
-
Circumvention of vector-specific neutralizing antibody response by alternating use of human and non-human adenoviruses: Implications in gene therapy
-
Moffatt S, Hays J, HogenEsch H, Mittal SK. Circumvention of vector-specific neutralizing antibody response by alternating use of human and non-human adenoviruses: implications in gene therapy. Virology 2000; 272: 159-67.
-
(2000)
Virology
, vol.272
, pp. 159-167
-
-
Moffatt, S.1
Hays, J.2
HogenEsch, H.3
Mittal, S.K.4
-
225
-
-
0036956812
-
Encapsulation of recombinant adenovirus into alginate microspheres circumvents vector-specific immune response
-
Sailaja G, HogenEsch H, North A, Hays J, Mittal SK. Encapsulation of recombinant adenovirus into alginate microspheres circumvents vector-specific immune response. Gene Ther 2002; 9: 1722-9.
-
(2002)
Gene Ther
, vol.9
, pp. 1722-1729
-
-
Sailaja, G.1
HogenEsch, H.2
North, A.3
Hays, J.4
Mittal, S.K.5
-
226
-
-
38649135439
-
Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor
-
Morrison J, Briggs SS, Green N, et al. Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor. Mol Ther 2008; 16: 244-51.
-
(2008)
Mol Ther
, vol.16
, pp. 244-251
-
-
Morrison, J.1
Briggs, S.S.2
Green, N.3
-
227
-
-
33947242506
-
Incorporation of a lamininderived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins
-
Stevenson M, Hale AB, Hale SJ, et al. Incorporation of a lamininderived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins. Cancer Gene Ther 2007; 14: 335-45.
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 335-345
-
-
Stevenson, M.1
Hale, A.B.2
Hale, S.J.3
-
228
-
-
0034632396
-
Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions
-
Croyle MA, Yu QC, Wilson JM. Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions. Hum Gene Ther 2000; 11: 1713-22.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 1713-1722
-
-
Croyle, M.A.1
Yu, Q.C.2
Wilson, J.M.3
-
229
-
-
40849095967
-
Development of PEGylated adenovirus vector with targeting ligand
-
Eto Y, Yoshioka Y, Mukai Y, Okada N, Nakagawa S. Development of PEGylated adenovirus vector with targeting ligand. Int J Pharm 2008; 354: 3-8.
-
(2008)
Int J Pharm
, vol.354
, pp. 3-8
-
-
Eto, Y.1
Yoshioka, Y.2
Mukai, Y.3
Okada, N.4
Nakagawa, S.5
-
230
-
-
0033946856
-
Targeting of adenoviral vectors through a bispecific single-chain antibody
-
Haisma HJ, Grill J, Curiel DT, et al. Targeting of adenoviral vectors through a bispecific single-chain antibody. Cancer Gene Ther 2000; 7: 901-4.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 901-904
-
-
Haisma, H.J.1
Grill, J.2
Curiel, D.T.3
-
231
-
-
0032858151
-
Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM
-
Haisma HJ, Pinedo HM, Rijswijk A, et al. Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM. Gene Ther 1999; 6: 1469-74.
-
(1999)
Gene Ther
, vol.6
, pp. 1469-1474
-
-
Haisma, H.J.1
Pinedo, H.M.2
Rijswijk, A.3
-
232
-
-
0034917310
-
Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors
-
Heideman DA, Snijders PJ, Craanen ME, et al. Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors. Cancer Gene Ther 2001; 8: 342-51.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 342-351
-
-
Heideman, D.A.1
Snijders, P.J.2
Craanen, M.E.3
-
233
-
-
0034963191
-
Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105)
-
Nettelbeck DM, Miller DW, Jerome V, et al. Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105). Mol Ther 2001; 3: 882-91.
-
(2001)
Mol Ther
, vol.3
, pp. 882-891
-
-
Nettelbeck, D.M.1
Miller, D.W.2
Jerome, V.3
-
234
-
-
10244230493
-
Recombinant bispecific antibodies for the targeting of adenoviruses to CEA-expressing tumour cells: A comparative analysis of bacterially expressed single-chain diabody and tandem scFv
-
Korn T, Nettelbeck DM, Volkel T, Muller R, Kontermann RE. Recombinant bispecific antibodies for the targeting of adenoviruses to CEA-expressing tumour cells: a comparative analysis of bacterially expressed single-chain diabody and tandem scFv. J Gene Med 2004; 6: 642-51.
-
(2004)
J Gene Med
, vol.6
, pp. 642-651
-
-
Korn, T.1
Nettelbeck, D.M.2
Volkel, T.3
Muller, R.4
Kontermann, R.E.5
-
235
-
-
0345687967
-
Retargeting of adenoviral infection to melanoma: Combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA
-
Nettelbeck DM, Rivera AA, Kupsch J, et al. Retargeting of adenoviral infection to melanoma: combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA. Int J Cancer 2004; 108: 136-45.
-
(2004)
Int J Cancer
, vol.108
, pp. 136-145
-
-
Nettelbeck, D.M.1
Rivera, A.A.2
Kupsch, J.3
-
236
-
-
0033740724
-
Selectivity of TAG-72-targeted adenovirus gene transfer to primary ovarian carcinoma cells versus autologous mesothelial cells in vitro
-
Kelly FJ, Miller CR, Buchsbaum DJ, et al. Selectivity of TAG-72-targeted adenovirus gene transfer to primary ovarian carcinoma cells versus autologous mesothelial cells in vitro. Clin Cancer Res 2000; 6: 4323-33.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4323-4333
-
-
Kelly, F.J.1
Miller, C.R.2
Buchsbaum, D.J.3
-
237
-
-
0029907239
-
Targeted gene delivery by tropism-modified adenoviral vectors
-
Douglas JT, Rogers BE, Rosenfeld ME, et al. Targeted gene delivery by tropism-modified adenoviral vectors. Nat Biotechnol 1996; 14: 1574-8.
-
(1996)
Nat Biotechnol
, vol.14
, pp. 1574-1578
-
-
Douglas, J.T.1
Rogers, B.E.2
Rosenfeld, M.E.3
-
238
-
-
0033925797
-
Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells
-
Dmitriev I, Kashentseva E, Rogers BE, Krasnykh V, Curiel DT. Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells. J Virol 2000; 74: 6875-84.
-
(2000)
J Virol
, vol.74
, pp. 6875-6884
-
-
Dmitriev, I.1
Kashentseva, E.2
Rogers, B.E.3
Krasnykh, V.4
Curiel, D.T.5
-
239
-
-
0041649396
-
Metabolically biotinylated adenovirus for cell targeting, ligand screening, and vector purification
-
Parrott MB, Adams KE, Mercier GT, et al. Metabolically biotinylated adenovirus for cell targeting, ligand screening, and vector purification. Mol Ther 2003; 8: 688-700.
-
(2003)
Mol Ther
, vol.8
, pp. 688-700
-
-
Parrott, M.B.1
Adams, K.E.2
Mercier, G.T.3
-
240
-
-
0031775399
-
An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptorindependent cell entry mechanism
-
Dmitriev I, Krasnykh V, Miller CR, et al. An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptorindependent cell entry mechanism. J Virol 1998; 72: 9706-13.
-
(1998)
J Virol
, vol.72
, pp. 9706-9713
-
-
Dmitriev, I.1
Krasnykh, V.2
Miller, C.R.3
-
241
-
-
0031913203
-
Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob
-
Krasnykh V, Dmitriev I, Mikheeva G, et al. Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob. J Virol 1998; 72: 1844-52.
-
(1998)
J Virol
, vol.72
, pp. 1844-1852
-
-
Krasnykh, V.1
Dmitriev, I.2
Mikheeva, G.3
-
242
-
-
0028790770
-
Addition of a short peptide ligand to the adenovirus fiber protein
-
Michael SI, Hong JS, Curiel DT, Engler JA. Addition of a short peptide ligand to the adenovirus fiber protein. Gene Ther 1995; 2: 660-8.
-
(1995)
Gene Ther
, vol.2
, pp. 660-668
-
-
Michael, S.I.1
Hong, J.S.2
Curiel, D.T.3
Engler, J.A.4
-
243
-
-
0030768124
-
Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins
-
Wickham TJ, Tzeng E, Shears LL, 2nd, et al. Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins. J Virol 1997; 71: 8221-9.
-
(1997)
J Virol
, vol.71
, pp. 8221-8229
-
-
Wickham, T.J.1
Tzeng, E.2
Shears 2nd, L.L.3
-
244
-
-
0029858682
-
Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types
-
Wickham TJ, Roelvink PW, Brough DE, Kovesdi I. Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types. Nat Biotechnol 1996; 14: 1570-3.
-
(1996)
Nat Biotechnol
, vol.14
, pp. 1570-1573
-
-
Wickham, T.J.1
Roelvink, P.W.2
Brough, D.E.3
Kovesdi, I.4
-
245
-
-
0036377931
-
Double modification of adenovirus fiber with RGD and polylysine motifs improves coxsackievirusadenovirus receptor-independent gene transfer efficiency
-
Wu H, Seki T, Dmitriev I, et al. Double modification of adenovirus fiber with RGD and polylysine motifs improves coxsackievirusadenovirus receptor-independent gene transfer efficiency. Hum Gene Ther 2002; 13: 1647-53.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1647-1653
-
-
Wu, H.1
Seki, T.2
Dmitriev, I.3
-
246
-
-
0344661722
-
Generation of fiber-modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob
-
Koizumi N, Mizuguchi H, Utoguchi N, Watanabe Y, Hayakawa T. Generation of fiber-modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob. J Gene Med 2003; 5: 267-76.
-
(2003)
J Gene Med
, vol.5
, pp. 267-276
-
-
Koizumi, N.1
Mizuguchi, H.2
Utoguchi, N.3
Watanabe, Y.4
Hayakawa, T.5
-
247
-
-
33947389680
-
Tropism modification of adenovirus vectors by peptide ligand insertion into various positions of the adenovirus serotype 41 short-fiber knob domain
-
Hesse A, Kosmides D, Kontermann RE, Nettelbeck DM. Tropism modification of adenovirus vectors by peptide ligand insertion into various positions of the adenovirus serotype 41 short-fiber knob domain. J Virol 2007; 81: 2688-99.
-
(2007)
J Virol
, vol.81
, pp. 2688-2699
-
-
Hesse, A.1
Kosmides, D.2
Kontermann, R.E.3
Nettelbeck, D.M.4
-
248
-
-
0033061221
-
RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection
-
Vigne E, Mahfouz I, Dedieu JF, et al. RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection. J Virol 1999; 73: 5156-61.
-
(1999)
J Virol
, vol.73
, pp. 5156-5161
-
-
Vigne, E.1
Mahfouz, I.2
Dedieu, J.F.3
-
249
-
-
14744267832
-
Identification of sites in adenovirus hexon for foreign peptide incorporation
-
Wu H, Han T, Belousova N, et al. Identification of sites in adenovirus hexon for foreign peptide incorporation. J Virol 2005; 79: 3382-90.
-
(2005)
J Virol
, vol.79
, pp. 3382-3390
-
-
Wu, H.1
Han, T.2
Belousova, N.3
-
250
-
-
0032851439
-
Construction of a pseudoreceptor that mediates transduction by adenoviruses expressing a ligand in fiber or penton base
-
Einfeld DA, Brough DE, Roelvink PW, Kovesdi I, Wickham TJ. Construction of a pseudoreceptor that mediates transduction by adenoviruses expressing a ligand in fiber or penton base. J Virol 1999; 73: 9130-6.
-
(1999)
J Virol
, vol.73
, pp. 9130-9136
-
-
Einfeld, D.A.1
Brough, D.E.2
Roelvink, P.W.3
Kovesdi, I.4
Wickham, T.J.5
-
251
-
-
0036632175
-
Engineering of adenovirus vectors containing heterologous peptide sequences in the C terminus of capsid protein IX
-
Dmitriev IP, Kashentseva EA, Curiel DT. Engineering of adenovirus vectors containing heterologous peptide sequences in the C terminus of capsid protein IX. J Virol 2002; 76: 6893-9.
-
(2002)
J Virol
, vol.76
, pp. 6893-6899
-
-
Dmitriev, I.P.1
Kashentseva, E.A.2
Curiel, D.T.3
-
252
-
-
1842457786
-
Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX
-
Vellinga J, Rabelink MJ, Cramer SJ, et al. Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX. J Virol 2004; 78: 3470-9.
-
(2004)
J Virol
, vol.78
, pp. 3470-3479
-
-
Vellinga, J.1
Rabelink, M.J.2
Cramer, S.J.3
-
253
-
-
2342459114
-
Use of adenovirus protein IX (pIX) to display large polypeptides on the virion--generation of fluorescent virus through the incorporation of pIX-GFP
-
Meulenbroek RA, Sargent KL, Lunde J, Jasmin BJ, Parks RJ. Use of adenovirus protein IX (pIX) to display large polypeptides on the virion--generation of fluorescent virus through the incorporation of pIX-GFP. Mol Ther 2004; 9: 617-24.
-
(2004)
Mol Ther
, vol.9
, pp. 617-624
-
-
Meulenbroek, R.A.1
Sargent, K.L.2
Lunde, J.3
Jasmin, B.J.4
Parks, R.J.5
-
254
-
-
33747259575
-
Transductional targeting of adenovirus vectors for gene therapy
-
Glasgow JN, Everts M, Curiel DT. Transductional targeting of adenovirus vectors for gene therapy. Cancer Gene Ther 2006; 13: 830-44.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 830-844
-
-
Glasgow, J.N.1
Everts, M.2
Curiel, D.T.3
-
255
-
-
37849014587
-
Modification of adenovirus capsid with a designed protein ligand yields a gene vector targeted to a major molecular marker of cancer
-
Belousova N, Mikheeva G, Gelovani J, Krasnykh V. Modification of adenovirus capsid with a designed protein ligand yields a gene vector targeted to a major molecular marker of cancer. J Virol 2008; 82: 630-7.
-
(2008)
J Virol
, vol.82
, pp. 630-637
-
-
Belousova, N.1
Mikheeva, G.2
Gelovani, J.3
Krasnykh, V.4
-
256
-
-
0036381953
-
Genetic modification of adenovirus 5 tropism by a novel class of ligands based on a three-helix bundle scaffold derived from staphylococcal protein A
-
Henning P, Magnusson MK, Gunneriusson E, et al. Genetic modification of adenovirus 5 tropism by a novel class of ligands based on a three-helix bundle scaffold derived from staphylococcal protein A. Hum Gene Ther 2002; 13: 1427-39.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1427-1439
-
-
Henning, P.1
Magnusson, M.K.2
Gunneriusson, E.3
-
257
-
-
0030835822
-
Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain
-
Nord K, Gunneriusson E, Ringdahl J, et al. Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain. Nat Biotechnol 1997; 15: 772-7.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 772-777
-
-
Nord, K.1
Gunneriusson, E.2
Ringdahl, J.3
-
258
-
-
0037903340
-
A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism
-
Takayama K, Reynolds PN, Short JJ, et al. A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism. Virology 2003; 309: 282-93.
-
(2003)
Virology
, vol.309
, pp. 282-293
-
-
Takayama, K.1
Reynolds, P.N.2
Short, J.J.3
-
259
-
-
0035871784
-
Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgeneencoded antigen presentation to cytotoxic T cells
-
Rea D, Havenga MJ, van Den Assem M, et al. Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgeneencoded antigen presentation to cytotoxic T cells. J Immunol 2001; 166: 5236-44.
-
(2001)
J Immunol
, vol.166
, pp. 5236-5244
-
-
Rea, D.1
Havenga, M.J.2
van Den Assem, M.3
-
260
-
-
4344654146
-
Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats
-
Nicol CG, Graham D, Miller WH, et al. Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats. Mol Ther 2004; 10: 344-54.
-
(2004)
Mol Ther
, vol.10
, pp. 344-354
-
-
Nicol, C.G.1
Graham, D.2
Miller, W.H.3
-
261
-
-
27944453541
-
A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy
-
Stoff-Khalili MA, Rivera AA, Glasgow JN, et al. A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy. Gene Ther 2005; 12: 1696-706.
-
(2005)
Gene Ther
, vol.12
, pp. 1696-1706
-
-
Stoff-Khalili, M.A.1
Rivera, A.A.2
Glasgow, J.N.3
-
262
-
-
2942528908
-
An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism
-
Glasgow JN, Kremer EJ, Hemminki A, et al. An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism. Virology 2004; 324: 103-16.
-
(2004)
Virology
, vol.324
, pp. 103-116
-
-
Glasgow, J.N.1
Kremer, E.J.2
Hemminki, A.3
-
263
-
-
33745028819
-
An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice
-
Nakayama M, Both GW, Banizs B, et al. An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice. Virology 2006; 350: 103-15.
-
(2006)
Virology
, vol.350
, pp. 103-115
-
-
Nakayama, M.1
Both, G.W.2
Banizs, B.3
-
264
-
-
2442544553
-
Genetic replacement of the adenovirus shaft fiber reduces liver tropism in ovarian cancer gene therapy
-
Breidenbach M, Rein DT, Wang M, et al. Genetic replacement of the adenovirus shaft fiber reduces liver tropism in ovarian cancer gene therapy. Hum Gene Ther 2004; 15: 509-18.
-
(2004)
Hum Gene Ther
, vol.15
, pp. 509-518
-
-
Breidenbach, M.1
Rein, D.T.2
Wang, M.3
-
265
-
-
0036154758
-
Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells
-
Kanerva A, Mikheeva GV, Krasnykh V, et al. Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells. Clin Cancer Res 2002; 8: 275-80.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 275-280
-
-
Kanerva, A.1
Mikheeva, G.V.2
Krasnykh, V.3
-
266
-
-
33646910484
-
CD46 represents a target for adenoviral gene therapy of malignant glioma
-
Ulasov IV, Tyler MA, Zheng S, Han Y, Lesniak MS. CD46 represents a target for adenoviral gene therapy of malignant glioma. Hum Gene Ther 2006; 17: 556-64.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 556-564
-
-
Ulasov, I.V.1
Tyler, M.A.2
Zheng, S.3
Han, Y.4
Lesniak, M.S.5
-
267
-
-
34047115830
-
Fiber-knob modifications enhance adenoviral tropism and gene transfer in malignant glioma
-
Zheng S, Ulasov IV, Han Y, et al. Fiber-knob modifications enhance adenoviral tropism and gene transfer in malignant glioma. J Gene Med 2007; 9: 151-60.
-
(2007)
J Gene Med
, vol.9
, pp. 151-160
-
-
Zheng, S.1
Ulasov, I.V.2
Han, Y.3
-
268
-
-
33751063989
-
Evaluation of adenovirus vectors containing serotype 35 fibers for tumor targeting
-
Ni S, Gaggar A, Di Paolo N, et al. Evaluation of adenovirus vectors containing serotype 35 fibers for tumor targeting. Cancer Gene Ther 2006; 13: 1072-81.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 1072-1081
-
-
Ni, S.1
Gaggar, A.2
Di Paolo, N.3
-
269
-
-
33750505898
-
Head and neck cancer cells are efficiently infected by Ad5/35 hybrid virus
-
Suominen E, Toivonen R, Grenman R, Savontaus M. Head and neck cancer cells are efficiently infected by Ad5/35 hybrid virus. J Gene Med 2006; 8: 1223-31.
-
(2006)
J Gene Med
, vol.8
, pp. 1223-1231
-
-
Suominen, E.1
Toivonen, R.2
Grenman, R.3
Savontaus, M.4
-
270
-
-
34249016412
-
A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway
-
Tsuruta Y, Pereboeva L, Glasgow JN, et al. A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway. Clin Cancer Res 2007; 13: 2777-83.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2777-2783
-
-
Tsuruta, Y.1
Pereboeva, L.2
Glasgow, J.N.3
-
271
-
-
24644451047
-
Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation
-
Schoggins JW, Nociari M, Philpott N, Falck-Pedersen E. Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation. J Virol 2005; 79: 11627-37.
-
(2005)
J Virol
, vol.79
, pp. 11627-11637
-
-
Schoggins, J.W.1
Nociari, M.2
Philpott, N.3
Falck-Pedersen, E.4
-
272
-
-
0141844624
-
The maturation of murine dendritic cells induced by human adenovirus is mediated by the fiber knob domain
-
Molinier-Frenkel V, Prevost-Blondel A, Hong SS, et al. The maturation of murine dendritic cells induced by human adenovirus is mediated by the fiber knob domain. J Biol Chem 2003; 278: 37175-82.
-
(2003)
J Biol Chem
, vol.278
, pp. 37175-37182
-
-
Molinier-Frenkel, V.1
Prevost-Blondel, A.2
Hong, S.S.3
-
273
-
-
44349193581
-
Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo
-
Kalyuzhniy O, Di Paolo NC, Silvestry M, et al. Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo. Proc Natl Acad Sci USA 2008; 105: 5483-8.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5483-5488
-
-
Kalyuzhniy, O.1
Di Paolo, N.C.2
Silvestry, M.3
-
274
-
-
38849134279
-
Adenovirus serotype 5 hexon mediates liver gene transfer
-
Waddington SN, McVey JH, Bhella D, et al. Adenovirus serotype 5 hexon mediates liver gene transfer. Cell 2008; 132: 397-409.
-
(2008)
Cell
, vol.132
, pp. 397-409
-
-
Waddington, S.N.1
McVey, J.H.2
Bhella, D.3
-
275
-
-
0029869840
-
Adenovirus type 5 and 7 capsid chimera: Fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes
-
Gall J, Kass-Eisler A, Leinwand L, Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J Virol 1996; 70: 2116-23.
-
(1996)
J Virol
, vol.70
, pp. 2116-2123
-
-
Gall, J.1
Kass-Eisler, A.2
Leinwand, L.3
Falck-Pedersen, E.4
-
276
-
-
0023908115
-
Neutralization of adenoviruses: Kinetics, stoichiometry, and mechanisms
-
Wohlfart C. Neutralization of adenoviruses: kinetics, stoichiometry, and mechanisms. J Virol 1988; 62: 2321-8.
-
(1988)
J Virol
, vol.62
, pp. 2321-2328
-
-
Wohlfart, C.1
-
277
-
-
31844448804
-
Development of nonhuman adenoviruses as vaccine vectors
-
Bangari DS, Mittal SK. Development of nonhuman adenoviruses as vaccine vectors. Vaccine 2006; 24: 849-62.
-
(2006)
Vaccine
, vol.24
, pp. 849-862
-
-
Bangari, D.S.1
Mittal, S.K.2
-
278
-
-
33749999808
-
New serotypes of adenoviral vectors
-
Stone D, Lieber A. New serotypes of adenoviral vectors. Curr Opin Mol Ther 2006; 8: 423-31.
-
(2006)
Curr Opin Mol Ther
, vol.8
, pp. 423-431
-
-
Stone, D.1
Lieber, A.2
-
279
-
-
4444383341
-
Porcine adenoviral vectors evade preexisting humoral immunity to adenoviruses and efficiently infect both human and murine cells in culture
-
Bangari DS, Mittal SK. Porcine adenoviral vectors evade preexisting humoral immunity to adenoviruses and efficiently infect both human and murine cells in culture. Virus Res 2004; 105: 127-36.
-
(2004)
Virus Res
, vol.105
, pp. 127-136
-
-
Bangari, D.S.1
Mittal, S.K.2
-
280
-
-
0032718710
-
Porcine adenovirus-3 as a helper-dependent expression vector
-
Reddy PS, Idamakanti N, Babiuk LA, Mehtali M, Tikoo SK. Porcine adenovirus-3 as a helper-dependent expression vector. J Gen Virol 1999; 80: 2909-16.
-
(1999)
J Gen Virol
, vol.80
, pp. 2909-2916
-
-
Reddy, P.S.1
Idamakanti, N.2
Babiuk, L.A.3
Mehtali, M.4
Tikoo, S.K.5
-
281
-
-
0028896224
-
Development of a bovine adenovirus type 3-based expression vector
-
Mittal SK, Prevec L, Graham FL, Babiuk LA. Development of a bovine adenovirus type 3-based expression vector. J Gen Virol 1995; 76: 93-102.
-
(1995)
J Gen Virol
, vol.76
, pp. 93-102
-
-
Mittal, S.K.1
Prevec, L.2
Graham, F.L.3
Babiuk, L.A.4
-
282
-
-
0032853359
-
Replication-defective bovine adenovirus type 3 as an expression vector
-
Reddy PS, Idamakanti N, Chen Y, et al. Replication-defective bovine adenovirus type 3 as an expression vector. J Virol 1999; 73: 9137-44.
-
(1999)
J Virol
, vol.73
, pp. 9137-9144
-
-
Reddy, P.S.1
Idamakanti, N.2
Chen, Y.3
-
283
-
-
11844264045
-
Comparative transduction efficiencies of human and nonhuman adenoviral vectors in human, murine, bovine, and porcine cells in culture
-
Bangari DS, Shukla S, Mittal SK. Comparative transduction efficiencies of human and nonhuman adenoviral vectors in human, murine, bovine, and porcine cells in culture. Biochem Biophys Res Commun 2005; 327: 960-6.
-
(2005)
Biochem Biophys Res Commun
, vol.327
, pp. 960-966
-
-
Bangari, D.S.1
Shukla, S.2
Mittal, S.K.3
-
284
-
-
18844371145
-
Bovine adenovirus type 3 internalization is independent of primary receptors of human adenovirus type 5 and porcine adenovirus type 3
-
Bangari DS, Sharma A, Mittal SK. Bovine adenovirus type 3 internalization is independent of primary receptors of human adenovirus type 5 and porcine adenovirus type 3. Biochem Biophys Res Commun 2005; 331: 1478-84.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 1478-1484
-
-
Bangari, D.S.1
Sharma, A.2
Mittal, S.K.3
-
285
-
-
11844275041
-
Porcine adenovirus serotype 3 internalization is independent of CAR and alphavbeta3 or alphavbeta5 integrin
-
Bangari DS, Mittal SK. Porcine adenovirus serotype 3 internalization is independent of CAR and alphavbeta3 or alphavbeta5 integrin. Virology 2005; 332: 157-66.
-
(2005)
Virology
, vol.332
, pp. 157-166
-
-
Bangari, D.S.1
Mittal, S.K.2
-
286
-
-
0037301795
-
A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model
-
Hemminki A, Kanerva A, Kremer EJ, et al. A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model. Mol Ther 2003; 7: 163-73.
-
(2003)
Mol Ther
, vol.7
, pp. 163-173
-
-
Hemminki, A.1
Kanerva, A.2
Kremer, E.J.3
-
287
-
-
22944434253
-
Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity
-
Dilley J, Reddy S, Ko D, et al. Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity. Cancer Gene Ther 2005; 12: 715-22.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 715-722
-
-
Dilley, J.1
Reddy, S.2
Ko, D.3
-
288
-
-
0010349948
-
Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model
-
Freytag SO, Paielli D, Wing M, et al. Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model. Int J Radiat Oncol Biol Phys 2002; 54: 873-85.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 873-885
-
-
Freytag, S.O.1
Paielli, D.2
Wing, M.3
-
289
-
-
33847212832
-
Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer
-
Freytag SO, Stricker H, Peabody J, et al. Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer. Mol Ther 2007; 15: 636-42.
-
(2007)
Mol Ther
, vol.15
, pp. 636-642
-
-
Freytag, S.O.1
Stricker, H.2
Peabody, J.3
-
290
-
-
36749027167
-
Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells
-
Emdad L, Lebedeva IV, Su ZZ, et al. Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells. Mol Cancer Ther 2007; 6: 2985-94.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2985-2994
-
-
Emdad, L.1
Lebedeva, I.V.2
Su, Z.Z.3
-
291
-
-
34249027011
-
Adenoviral-mediated PTEN expression radiosensitizes non-small cell lung cancer cells by suppressing DNA repair capacity
-
Pappas G, Zumstein LA, Munshi A, Hobbs M, Meyn RE. Adenoviral-mediated PTEN expression radiosensitizes non-small cell lung cancer cells by suppressing DNA repair capacity. Cancer Gene Ther 2007; 14: 543-9.
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 543-549
-
-
Pappas, G.1
Zumstein, L.A.2
Munshi, A.3
Hobbs, M.4
Meyn, R.E.5
-
292
-
-
35048895704
-
Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs
-
Folmer Y, Schneider M, Blum HE, Hafkemeyer P. Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs. Cancer Gene Ther 2007; 14: 875-84.
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 875-884
-
-
Folmer, Y.1
Schneider, M.2
Blum, H.E.3
Hafkemeyer, P.4
-
293
-
-
40749104734
-
Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis
-
Gregory-Bass RC, Olatinwo M, Xu W, et al. Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis. Int J Cancer 2008; 122: 1923-30.
-
(2008)
Int J Cancer
, vol.122
, pp. 1923-1930
-
-
Gregory-Bass, R.C.1
Olatinwo, M.2
Xu, W.3
-
294
-
-
0035879042
-
CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity
-
Chen Y, DeWeese T, Dilley J, et al. CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity. Cancer Res 2001; 61: 5453-60.
-
(2001)
Cancer Res
, vol.61
, pp. 5453-5460
-
-
Chen, Y.1
DeWeese, T.2
Dilley, J.3
-
295
-
-
0037442441
-
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression
-
Hemminki A, Kanerva A, Liu B, et al. Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression. Cancer Res 2003; 63: 847-53.
-
(2003)
Cancer Res
, vol.63
, pp. 847-853
-
-
Hemminki, A.1
Kanerva, A.2
Liu, B.3
-
296
-
-
38449110161
-
Novel approaches for chemosensitization of breast cancer cells: The E1A story
-
Liao Y, Yu D, Hung MC. Novel approaches for chemosensitization of breast cancer cells: the E1A story. Adv Exp Med Biol 2007; 608: 144-69.
-
(2007)
Adv Exp Med Biol
, vol.608
, pp. 144-169
-
-
Liao, Y.1
Yu, D.2
Hung, M.C.3
-
297
-
-
0033426763
-
In vivo radio-sensitizing effect of the adenovirus E1A gene in murine and human malignant tumors
-
Martin-Duque P, Sanchez-Prieto R, Romero J, et al. In vivo radio-sensitizing effect of the adenovirus E1A gene in murine and human malignant tumors. Int J Oncol 1999; 15: 1163-8.
-
(1999)
Int J Oncol
, vol.15
, pp. 1163-1168
-
-
Martin-Duque, P.1
Sanchez-Prieto, R.2
Romero, J.3
-
298
-
-
0035863499
-
Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel
-
Yu DC, Chen Y, Dilley J, et al. Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel. Cancer Res 2001; 61: 517-25.
-
(2001)
Cancer Res
, vol.61
, pp. 517-525
-
-
Yu, D.C.1
Chen, Y.2
Dilley, J.3
-
299
-
-
0042326321
-
Technology evaluation: TNFerade, GenVec
-
Kircheis R, Wagner E. Technology evaluation: TNFerade, GenVec. Curr Opin Mol Ther 2003; 5: 437-47.
-
(2003)
Curr Opin Mol Ther
, vol.5
, pp. 437-447
-
-
Kircheis, R.1
Wagner, E.2
-
300
-
-
4644222753
-
Chemoinducible gene therapy: A strategy to enhance doxorubicin antitumor activity
-
Lopez CA, Kimchi ET, Mauceri HJ, et al. Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity. Mol Cancer Ther 2004; 3: 1167-75.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1167-1175
-
-
Lopez, C.A.1
Kimchi, E.T.2
Mauceri, H.J.3
-
301
-
-
1442332187
-
TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: A phase I study in patients with solid tumors
-
Senzer N, Mani S, Rosemurgy A, et al. TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors. J Clin Oncol 2004; 22: 592-601.
-
(2004)
J Clin Oncol
, vol.22
, pp. 592-601
-
-
Senzer, N.1
Mani, S.2
Rosemurgy, A.3
-
302
-
-
4444295881
-
A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities
-
Mundt AJ, Vijayakumar S, Nemunaitis J, et al. A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities. Clin Cancer Res 2004; 10: 5747-53.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5747-5753
-
-
Mundt, A.J.1
Vijayakumar, S.2
Nemunaitis, J.3
-
303
-
-
33845994768
-
Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity
-
Power AT, Wang J, Falls TJ, et al. Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity. Mol Ther 2007; 15: 123-30.
-
(2007)
Mol Ther
, vol.15
, pp. 123-130
-
-
Power, A.T.1
Wang, J.2
Falls, T.J.3
-
304
-
-
33847791626
-
Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model
-
Tang Y, Han T, Everts M, et al. Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model. Gene Ther 2007; 14: 523-32.
-
(2007)
Gene Ther
, vol.14
, pp. 523-532
-
-
Tang, Y.1
Han, T.2
Everts, M.3
-
305
-
-
3042606344
-
Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis
-
Zhu ZB, Makhija SK, Lu B, et al. Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis. Virology 2004; 325: 116-28.
-
(2004)
Virology
, vol.325
, pp. 116-128
-
-
Zhu, Z.B.1
Makhija, S.K.2
Lu, B.3
-
306
-
-
0033693231
-
Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
-
Nemunaitis J, Ganly I, Khuri F, et al. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. Cancer Res 2000; 60: 6359-66.
-
(2000)
Cancer Res
, vol.60
, pp. 6359-6366
-
-
Nemunaitis, J.1
Ganly, I.2
Khuri, F.3
-
307
-
-
35048816872
-
A phase I trial of intravenous infusion of ONYX-015 and enbrel in solid tumor patients
-
Nemunaitis J, Senzer N, Sarmiento S, et al. A phase I trial of intravenous infusion of ONYX-015 and enbrel in solid tumor patients. Cancer Gene Ther 2007; 14: 885-93.
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 885-893
-
-
Nemunaitis, J.1
Senzer, N.2
Sarmiento, S.3
-
308
-
-
29344455240
-
Dual promoter-controlled oncolytic adenovirus CG5757 has strong tumor selectivity and significant antitumor efficacy in preclinical models
-
Li Y, Idamakanti N, Arroyo T, et al. Dual promoter-controlled oncolytic adenovirus CG5757 has strong tumor selectivity and significant antitumor efficacy in preclinical models. Clin Cancer Res 2005; 11: 8845-55.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8845-8855
-
-
Li, Y.1
Idamakanti, N.2
Arroyo, T.3
-
309
-
-
33947256232
-
A conditionally replicative, Wnt/ beta-catenin pathway-based adenovirus therapy for anaplastic thyroid cancer
-
Abbosh PH, Li X, Li L, et al. A conditionally replicative, Wnt/ beta-catenin pathway-based adenovirus therapy for anaplastic thyroid cancer. Cancer Gene Ther 2007; 14: 399-408.
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 399-408
-
-
Abbosh, P.H.1
Li, X.2
Li, L.3
-
310
-
-
19944384118
-
Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): Biologic outcome in advanced cancer patients
-
Tong AW, Nemunaitis J, Su D, et al. Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients. Mol Ther 2005; 11: 160-72.
-
(2005)
Mol Ther
, vol.11
, pp. 160-172
-
-
Tong, A.W.1
Nemunaitis, J.2
Su, D.3
-
311
-
-
34548277477
-
A phase I clinical trial of an adenovirus-mediated endostatin gene (E10A) in patients with solid tumors
-
Lin X, Huang H, Li S, et al. A phase I clinical trial of an adenovirus-mediated endostatin gene (E10A) in patients with solid tumors. Cancer Biol Ther 2007; 6: 648-53.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 648-653
-
-
Lin, X.1
Huang, H.2
Li, S.3
-
312
-
-
33845651381
-
A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Delta24, for the treatment of advanced breast cancer
-
Ranki T, Kanerva A, Ristimaki A, et al. A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Delta24, for the treatment of advanced breast cancer. Gene Ther 2007; 14: 58-67.
-
(2007)
Gene Ther
, vol.14
, pp. 58-67
-
-
Ranki, T.1
Kanerva, A.2
Ristimaki, A.3
-
313
-
-
33749556424
-
Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus
-
Tyler MA, Ulasov IV, Borovjagin A, et al. Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus. Mol Cancer Ther 2006; 5: 2408-16.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2408-2416
-
-
Tyler, M.A.1
Ulasov, I.V.2
Borovjagin, A.3
-
314
-
-
34547692979
-
A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: High rate of antitumor immune responses
-
Sterman DH, Recio A, Carroll RG, et al. A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses. Clin Cancer Res 2007; 13: 4456-66.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4456-4466
-
-
Sterman, D.H.1
Recio, A.2
Carroll, R.G.3
|