Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats

Molecular Therapy

Volumn 10, Issue 2, 2004, Pages 344-354

  Nicol, Campbell G ^a   Graham, Delyth ^a   Miller, William H ^a   White, Stephen J ^b   Smith, Theodore A G ^c   Nicklin, Stuart A ^a   Stevenson, Susan C ^c   Baker, Andrew H ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Adenovirus; CAR; Fiber; Hemagglutination; Integrins; Liver detargeting; Rat

Indexed keywords

ADENOVIRUS VECTOR; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; INTEGRIN; PROTEOHEPARAN SULFATE; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; GENE MUTATION; GENE TARGETING; GENETIC TRANSDUCTION; HEMAGGLUTINATION; IN VITRO STUDY; IN VIVO STUDY; LIVER; MALE; MOUSE STRAIN; NONHUMAN; PREDICTION; PROTEIN BINDING; RAT; RAT STRAIN; SEROTYPE; STRAIN DIFFERENCE; VIROGENESIS; VIRUS CAPSID; VIRUS INFECTIVITY; VIRUS MUTATION;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; CAPSID PROTEINS; CELL LINE; DNA, VIRAL; ENDOTHELIAL CELLS; GENETIC VECTORS; HEMAGGLUTINATION; HEPARAN SULFATE PROTEOGLYCANS; HEPATOCYTES; LIVER; MUTATION; RATS; RATS, INBRED WKY; RECEPTORS, VIRUS; TRANSDUCTION, GENETIC;

ADENOVIRIDAE;

EID: 4344654146     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.05.020     Document Type: Article

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