The role of p53 in chemosensitivity and radiosensitivity

Oncogene

Volumn 22, Issue 47 REV. ISS. 6, 2003, Pages 7486-7495

  El Deiry, Wafik S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Apoptosis; ASPP1; BRCA1; Cancer; Chemotherapy; CP 31398; HAUSP; MDM2; ONYX 015; p300; p53; P73; PAC1; Pare; Pirh2; Primal; Stability; Tissue specificity; Toxicity; Transcription

Indexed keywords

4 (3 DIMETHYLAMINOPROPYLAMINO) 2 (4 METHOXYSTYRYL)QUINAZOLINE; ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; ATM PROTEIN; BRCA1 PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; ELLIPTICINE; HISTONE ACETYLTRANSFERASE PCAF; MUTANT PROTEIN; NUCLEAR PROTEIN; ONYX 015; PACLITAXEL; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOPROTEIN; PIFITHRIN; PRIMA 1; PROTEIN; PROTEIN HAUSP; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN MDMX; PROTEIN P300; PROTEIN P53; PROTEIN P73; PROTEIN PIRH2; PROTEIN SIR3; SERINE; SILENT INFORMATION REGULATOR PROTEIN 2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UBIQUITIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; AUTOPHOSPHORYLATION; BIOLUMINESCENCE; CANCER INHIBITION; CELL KILLING; CHEMOSENSITIVITY; CLINICAL TRIAL; DNA DAMAGE; DNA REPAIR; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVITY; GENE ACTIVATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE REPLACEMENT THERAPY; GENE REPRESSION; GENE TARGETING; GENE THERAPY; GENETIC TRANSCRIPTION; HUMAN; IONIZING RADIATION; MITOSIS INHIBITION; MOLECULAR DYNAMICS; NONHUMAN; OXIDATIVE STRESS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RADIATION DOSE; RADIATION EXPOSURE; RADIOSENSITIVITY; REVIEW; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; TRANSCRIPTION INITIATION; TUMOR CELL; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION; WILD TYPE;

DNA DAMAGE; DRUG RESISTANCE, NEOPLASM; HUMANS; ORGAN SPECIFICITY; RADIATION TOLERANCE; TUMOR SUPPRESSOR PROTEIN P53;

ADENOVIRIDAE; ANIMALIA;

EID: 0345256634     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206949     Document Type: Review

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