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Volumn 13, Issue 14, 2002, Pages 1737-1750

New oncolytic adenoviruses with hypoxia- and estrogen receptor-regulated replication

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; ONCOLYTIC VIRUS; PROTEIN ADEHE2F; PROTEIN ADEHT2; TELOMERASE; TRANSCRIPTASE; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 0036399291     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/104303402760293574     Document Type: Article
Times cited : (106)

References (56)
  • 1
    • 0035503241 scopus 로고    scopus 로고
    • A Midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging
    • Adachi, Y., Reynolds, P.N., Yamamoto, M., Wang, M., Takayama, K., Matsubara, S., Muramatsu, T., and Curiel, D.T. (2001). A Midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging. Cancer Res. 61, 7882-7888.
    • (2001) Cancer Res. , vol.61 , pp. 7882-7888
    • Adachi, Y.1    Reynolds, P.N.2    Yamamoto, M.3    Wang, M.4    Takayama, K.5    Matsubara, S.6    Muramatsu, T.7    Curiel, D.T.8
  • 2
    • 0033926002 scopus 로고    scopus 로고
    • Replicative adenoviruses for cancer therapy
    • Alemany, R., Balague, C., and Curiel, C.T. (2000). Replicative adenoviruses for cancer therapy. Nat. Biotechnol. 18, 723-727.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 723-727
    • Alemany, R.1    Balague, C.2    Curiel, C.T.3
  • 3
    • 0036118404 scopus 로고    scopus 로고
    • Replication-selective viruses for cancer therapy
    • Biederer, C., Ries, S., Brandts, C.H., and McCormick, F. (2002). Replication-selective viruses for cancer therapy. J. Mol. Med. 80, 163-175.
    • (2002) J. Mol. Med. , vol.80 , pp. 163-175
    • Biederer, C.1    Ries, S.2    Brandts, C.H.3    McCormick, F.4
  • 6
    • 0035956240 scopus 로고    scopus 로고
    • The role of adenovirus E4orf4 protein in viral replication and cell killing
    • Branton, P.E., and Roopchand, D.E. (2001). The role of adenovirus E4orf4 protein in viral replication and cell killing. Oncogene 20, 7855-7865.
    • (2001) Oncogene , vol.20 , pp. 7855-7865
    • Branton, P.E.1    Roopchand, D.E.2
  • 9
    • 0035100867 scopus 로고    scopus 로고
    • Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy
    • Doronin, K., Kuppuswamy, M., Toth, K., Tollefson, A.E., Krajcsi, P., Krougliak, V., and Wold, W.S.M. (2001). Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy. J. Virol. 75, 3314-3324.
    • (2001) J. Virol. , vol.75 , pp. 3314-3324
    • Doronin, K.1    Kuppuswamy, M.2    Toth, K.3    Tollefson, A.E.4    Krajcsi, P.5    Krougliak, V.6    Wold, W.S.M.7
  • 10
    • 0031974628 scopus 로고    scopus 로고
    • Determinants of ligand specificity of estrogen receptor-α: Estrogen versus androgen discrimination
    • Ekena, K., Katzenellenbogen, J.A., and Katzenellenbogen, B.S. (1998). Determinants of ligand specificity of estrogen receptor-α: Estrogen versus androgen discrimination. J. Biol. Chem. 273, 693-699.
    • (1998) J. Biol. Chem. , vol.273 , pp. 693-699
    • Ekena, K.1    Katzenellenbogen, J.A.2    Katzenellenbogen, B.S.3
  • 11
    • 0023492063 scopus 로고
    • Adenovirus early region 4 is required for efficient virus particle assembly
    • Falgout, B., and Ketner, G. (1987). Adenovirus early region 4 is required for efficient virus particle assembly. J. Virol. 61, 3759-3768.
    • (1987) J. Virol. , vol.61 , pp. 3759-3768
    • Falgout, B.1    Ketner, G.2
  • 12
    • 0031451158 scopus 로고    scopus 로고
    • Viral transactivating proteins
    • Flint, J., and Shenk, T. (1997). Viral transactivating proteins. Annu. Rev. Genet. 31, 177-212.
    • (1997) Annu. Rev. Genet. , vol.31 , pp. 177-212
    • Flint, J.1    Shenk, T.2
  • 13
    • 0036200352 scopus 로고    scopus 로고
    • Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway
    • Fuerer, C., and Iggo, R. (2002). Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway. Gene Ther. 9, 270-281.
    • (2002) Gene Ther. , vol.9 , pp. 270-281
    • Fuerer, C.1    Iggo, R.2
  • 15
    • 0029763526 scopus 로고    scopus 로고
    • Regulation of dihydrofolate reductase gene expression and E2F components in human diploid fibroblasts during growth and senescence
    • Good, L., Dimri, G.P., Campisi, J., and Chen, K.Y. (1996). Regulation of dihydrofolate reductase gene expression and E2F components in human diploid fibroblasts during growth and senescence. J. Cell. Physiol. 168, 580-588.
    • (1996) J. Cell. Physiol. , vol.168 , pp. 580-588
    • Good, L.1    Dimri, G.P.2    Campisi, J.3    Chen, K.Y.4
  • 16
    • 0029894237 scopus 로고    scopus 로고
    • Telomere length regulation
    • Greider, C.W. (1996). Telomere length regulation. Annu Rev. Biochem. 65, 337-365.
    • (1996) Annu Rev. Biochem. , vol.65 , pp. 337-365
    • Greider, C.W.1
  • 17
    • 0022381043 scopus 로고
    • Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff
    • Halbert, D.N., Cutt, J.R., and Shenk, T. (1985). Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff. J. Virol. 56, 250-257.
    • (1985) J. Virol. , vol.56 , pp. 250-257
    • Halbert, D.N.1    Cutt, J.R.2    Shenk, T.3
  • 18
    • 0033166096 scopus 로고    scopus 로고
    • A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma
    • Hallenbeck, P.L., Chang, Y., Hay, C., Golightly, D., Stewart, D., Lin, J., Phipps, S., and Chiang, Y.L. (1999). A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma. Hum. Gene Ther. 10, 1721-1733.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1721-1733
    • Hallenbeck, P.L.1    Chang, Y.2    Hay, C.3    Golightly, D.4    Stewart, D.5    Lin, J.6    Phipps, S.7    Chiang, Y.L.8
  • 19
    • 0029901910 scopus 로고    scopus 로고
    • Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes
    • Harle-Bachor, C., and Boukamp, P. (1996). Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes. Proc. Natl. Acad. Sci. U.S.A. 93, 6476-6481.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 6476-6481
    • Harle-Bachor, C.1    Boukamp, P.2
  • 21
    • 0034692458 scopus 로고    scopus 로고
    • A novel, conditionally replicative adenovirus for the treatment of breast cancer that allows controlled replication of E1a-deleted adenoviral vectors
    • Hernandez-Alcoceba, R., Pihalja, M., Wicha, M.S., and Clarke, M.F. (2000). A novel, conditionally replicative adenovirus for the treatment of breast cancer that allows controlled replication of E1a-deleted adenoviral vectors. Hum. Gene Ther. 11, 2009-2024.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 2009-2024
    • Hernandez-Alcoceba, R.1    Pihalja, M.2    Wicha, M.S.3    Clarke, M.F.4
  • 22
    • 0035008659 scopus 로고    scopus 로고
    • Evaluation of a new dual-specificity promoter for selective induction of apoptosis in breast cancer cells
    • Hernandez-Alcoceba, R., Pihalja, M., Nunez, G., and Clarke, M.F. (2001). Evaluation of a new dual-specificity promoter for selective induction of apoptosis in breast cancer cells. Cancer Gene Ther. 8, 298-307.
    • (2001) Cancer Gene Ther. , vol.8 , pp. 298-307
    • Hernandez-Alcoceba, R.1    Pihalja, M.2    Nunez, G.3    Clarke, M.F.4
  • 23
    • 0033558281 scopus 로고    scopus 로고
    • Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene
    • Horikawa, I., Cable, P.L., Afshari, C., and Barrett, J.C. (1999). Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene. Cancer Res. 59, 826-830.
    • (1999) Cancer Res. , vol.59 , pp. 826-830
    • Horikawa, I.1    Cable, P.L.2    Afshari, C.3    Barrett, J.C.4
  • 24
    • 0028276864 scopus 로고
    • Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter
    • Hsiao, K., Mcmahon, S.L., and Farnham, P.J. (1994). Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev. 8, 1526-1537.
    • (1994) Genes Dev. , vol.8 , pp. 1526-1537
    • Hsiao, K.1    Mcmahon, S.L.2    Farnham, P.J.3
  • 26
    • 0028364529 scopus 로고
    • Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression
    • Johnson, D.G., Ohtani, K., and Nevins, J.R. (1994). Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev. 8, 1514-1525.
    • (1994) Genes Dev. , vol.8 , pp. 1514-1525
    • Johnson, D.G.1    Ohtani, K.2    Nevins, J.R.3
  • 28
    • 0035134629 scopus 로고    scopus 로고
    • Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: What have we learned?
    • Kirn, D. (2001). Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: What have we learned? Gene Ther. 8, 89-98.
    • (2001) Gene Ther. , vol.8 , pp. 89-98
    • Kirn, D.1
  • 30
    • 0036210741 scopus 로고    scopus 로고
    • Toward a new generation of conditionally replicating adenoviruses: Pairing tumor selectivity with maximal oncolysis
    • Kruyt, F., and Curiel, D.T. (2002). Toward a new generation of conditionally replicating adenoviruses: Pairing tumor selectivity with maximal oncolysis. Hum. Gene Ther. 13, 485-495.
    • (2002) Hum. Gene Ther. , vol.13 , pp. 485-495
    • Kruyt, F.1    Curiel, D.T.2
  • 31
    • 0033805534 scopus 로고    scopus 로고
    • Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC-1 antigen
    • Kurihara, T., Brough, D.E., Kovesdi, I., and Kufe, D.W. (2000). Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC-1 antigen. J. Clin. Invest. 106, 763-771.
    • (2000) J. Clin. Invest. , vol.106 , pp. 763-771
    • Kurihara, T.1    Brough, D.E.2    Kovesdi, I.3    Kufe, D.W.4
  • 32
    • 0035012605 scopus 로고    scopus 로고
    • Her2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner, E., Taghavi, P., Chiles, K., Mahon, P.C., and Semenza, G.L. (2001). Her2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol. Cell. Biol. 21, 3995-4004.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 33
    • 0035030329 scopus 로고    scopus 로고
    • The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters
    • Majumdar, A.S., Hughes, D.E., Lichtsteiner, S.P., Wang, Z., Lebkowski, J.S., and Vasserot, A.P. (2001). The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters. Gene Ther. 8, 568-578.
    • (2001) Gene Ther. , vol.8 , pp. 568-578
    • Majumdar, A.S.1    Hughes, D.E.2    Lichtsteiner, S.P.3    Wang, Z.4    Lebkowski, J.S.5    Vasserot, A.P.6
  • 34
    • 0035881263 scopus 로고    scopus 로고
    • A conditional replication-competent adenoviral vector, Ad-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis
    • Matsubara, S., Wada, Y., Gardner, T.A., Egawa, M., Park, M., Hsieh, C., Zhau, H.E., Kao, C., Kamidono, S., Gillenwater, J.Y., and Chung, K.W.K. (2001). A conditional replication-competent adenoviral vector, Ad-OC-E1a, to cotarget prostate cancer and bone stroma in an experimental model of androgen-independent prostate cancer bone metastasis. Cancer Res. 61, 6012-6019.
    • (2001) Cancer Res. , vol.61 , pp. 6012-6019
    • Matsubara, S.1    Wada, Y.2    Gardner, T.A.3    Egawa, M.4    Park, M.5    Hsieh, C.6    Zhau, H.E.7    Kao, C.8    Kamidono, S.9    Gillenwater, J.Y.10    Chung, K.W.K.11
  • 36
    • 0032553652 scopus 로고    scopus 로고
    • Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method
    • Mizuguchi, H., and Kay, M.A. (1998). Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method. Hum. Gene Ther. 20, 2577-2583.
    • (1998) Hum. Gene Ther. , vol.20 , pp. 2577-2583
    • Mizuguchi, H.1    Kay, M.A.2
  • 37
    • 0035893560 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo
    • Moulder, S.L., Yakes, F.M., Muthuswamy, S.K., Bianco, R., Simpson, J.F., and Arteaga, C.L. (2001). Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Cancer Res. 61, 8887-8895.
    • (2001) Cancer Res. , vol.61 , pp. 8887-8895
    • Moulder, S.L.1    Yakes, F.M.2    Muthuswamy, S.K.3    Bianco, R.4    Simpson, J.F.5    Arteaga, C.L.6
  • 38
    • 0028136903 scopus 로고
    • Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter
    • Neuman, E., Flemington, E.K, Sellers, W.R., and Kaelin, W.G. (1994). Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter. Mol. Cell. Biol. 14, 6607-6615.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6607-6615
    • Neuman, E.1    Flemington, E.K.2    Sellers, W.R.3    Kaelin, W.G.4
  • 39
    • 0030860227 scopus 로고    scopus 로고
    • Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector
    • Parr, M.J., Manome, Y., Tanaka, T., Wen, P., Kufe, D.W., Kaelin, W.G., and Fine, H.A. (1997). Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector. Nat. Med. 3, 1145-1149.
    • (1997) Nat. Med. , vol.3 , pp. 1145-1149
    • Parr, M.J.1    Manome, Y.2    Tanaka, T.3    Wen, P.4    Kufe, D.W.5    Kaelin, W.G.6    Fine, H.A.7
  • 40
    • 85047699837 scopus 로고    scopus 로고
    • E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis
    • Polager, S., Kalma, Y., Berkovich, E., and Ginsberg, D. (2002). E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis. Oncogene 21, 437-446.
    • (2002) Oncogene , vol.21 , pp. 437-446
    • Polager, S.1    Kalma, Y.2    Berkovich, E.3    Ginsberg, D.4
  • 43
    • 0029612231 scopus 로고
    • A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites
    • Sellers, W.R., Rodgers, J.W., and Kaelin, W.G. (1995). A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc. Natl. Acad. Sci. U.S.A. 92, 11544-11548.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 11544-11548
    • Sellers, W.R.1    Rodgers, J.W.2    Kaelin, W.G.3
  • 44
    • 0000557447 scopus 로고    scopus 로고
    • Adenoviridae: The viruses and their replication
    • B.N. Fields, D.M. Knipe, and P.M. Howley, eds. Lippincott-Raven, Philadelphia, PA
    • Shenk, T. (1996). Adenoviridae: The viruses and their replication. In Fields Virology. B.N. Fields, D.M. Knipe, and P.M. Howley, eds. (Lippincott-Raven, Philadelphia, PA) pp. 2111-2147.
    • (1996) Fields Virology , pp. 2111-2147
    • Shenk, T.1
  • 45
    • 0033082526 scopus 로고    scopus 로고
    • Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
    • Takakura, M., Kyo, S., Kanaya, T., Hirano, H., Takeda, J., Yutsudo, M., and Inoue, M. (1999). Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res. 59, 551-557.
    • (1999) Cancer Res. , vol.59 , pp. 551-557
    • Takakura, M.1    Kyo, S.2    Kanaya, T.3    Hirano, H.4    Takeda, J.5    Yutsudo, M.6    Inoue, M.7
  • 46
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
    • Talks, K.L., Turley, H., Gatter, K.C., Maxwell, P.H., Pugh, C.W., Ratcliffe, P.J., and Harris, A.L. (2000). The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am. J. Pathol. 157, 411-421.
    • (2000) Am. J. Pathol. , vol.157 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6    Harris, A.L.7
  • 47
    • 0035956214 scopus 로고    scopus 로고
    • Adenovirus early E4 genes in viral oncogenesis
    • Tauber, B., and Dobner, T. (2001). Adenovirus early E4 genes in viral oncogenesis. Oncogene 20, 7847-7854.
    • (2001) Oncogene , vol.20 , pp. 7847-7854
    • Tauber, B.1    Dobner, T.2
  • 48
    • 0037096881 scopus 로고    scopus 로고
    • An E2f-responsive replication-selective adenovirus targeted to the defective cell cycle in cancer cells: Potent antitumoral efficacy but no toxicity to normal cell
    • Tsukuda, K., Wiewrodt, R., Molnar-Kimber, K., Jovanovic, V.P., and Amin, K.M. (2002). An E2f-responsive replication-selective adenovirus targeted to the defective cell cycle in cancer cells: Potent antitumoral efficacy but no toxicity to normal cell. Cancer Res. 62, 3438-3447.
    • (2002) Cancer Res. , vol.62 , pp. 3438-3447
    • Tsukuda, K.1    Wiewrodt, R.2    Molnar-Kimber, K.3    Jovanovic, V.P.4    Amin, K.M.5
  • 49
    • 0032530136 scopus 로고    scopus 로고
    • Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts
    • Ulaner, G.A., Hu, J.F., Vu, T.H., Guidice, L.C., and Hoffman, A.R. (1998). Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts. Cancer Res. 58, 4168-4172.
    • (1998) Cancer Res. , vol.58 , pp. 4168-4172
    • Ulaner, G.A.1    Hu, J.F.2    Vu, T.H.3    Guidice, L.C.4    Hoffman, A.R.5
  • 50
    • 0030950881 scopus 로고    scopus 로고
    • Reliability of estrogen receptors in predicting response to antiestrogens
    • Valavaara, R. (1997). Reliability of estrogen receptors in predicting response to antiestrogens. Oncology 11, 14-18.
    • (1997) Oncology , vol.11 , pp. 14-18
    • Valavaara, R.1
  • 51
    • 0033054325 scopus 로고    scopus 로고
    • Insulation of a conditionally expressed transgene in an adenoviral vector
    • Vassaux, G., Hurst, H.C., and Lemoine, N.R. (1999). Insulation of a conditionally expressed transgene in an adenoviral vector. Gene Ther. 6, 1192-1197.
    • (1999) Gene Ther. , vol.6 , pp. 1192-1197
    • Vassaux, G.1    Hurst, H.C.2    Lemoine, N.R.3
  • 52
    • 0033577876 scopus 로고    scopus 로고
    • Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT)
    • Wick, M., Zubov, D., and Hagen, G. (1999). Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT). Gene 232, 97-106.
    • (1999) Gene , vol.232 , pp. 97-106
    • Wick, M.1    Zubov, D.2    Hagen, G.3
  • 54
    • 0033119603 scopus 로고    scopus 로고
    • Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy
    • Yu, D., Sakamoto, G.T., and Henderson, D.R. (1999). Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy. Cancer Res. 59, 1498-1504.
    • (1999) Cancer Res. , vol.59 , pp. 1498-1504
    • Yu, D.1    Sakamoto, G.T.2    Henderson, D.R.3


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