Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105)

Molecular Therapy

Volumn 3, Issue 6, 2001, Pages 882-891

  Nettelbeck, Dirk M ^a   Miller, Daniel W ^a   Jérôme, Valérie ^a   Zuzarte, Marylou ^a   Watkins, Sarah J ^b   Hawkins, Robert E ^b   Müller, Rolf ^a   Kontermann, Roland E ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

Adenovirus; Bispecific antibodies; Endothelial cells; Gene therapy; Phage display; Single chain diabody; Vascular targeting

Indexed keywords

BISPECIFIC ANTIBODY; CELL RECEPTOR; CELL SURFACE PROTEIN; ENDOGLIN; IMMUNOGLOBULIN FRAGMENT; INTEGRIN; RECOMBINANT ANTIBODY; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; VIRUS RECEPTOR;

ADENOVIRUS; ANGIOGENESIS; ANTIBODY LIBRARY; ARTICLE; BACTERIUM; CANCER; CANCER THERAPY; CELL LINE; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; COXSACKIE VIRUS; DRUG DELIVERY SYSTEM; ENDOTHELIUM CELL; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; PROTEIN DOMAIN; RECEPTOR BINDING; SIGNAL TRANSDUCTION; VASCULAR DISEASE; VIRUS CAPSID; VIRUS INFECTION; VIRUS RECOMBINANT;

ADENOVIRIDAE; BACTERIA (MICROORGANISMS); COXSACKIEVIRUS; MIRIDAE;

EID: 0034963191     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0342     Document Type: Article

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