A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism

Virology

Volumn 309, Issue 2, 2003, Pages 282-293

  Takayama, Koichi ^a   Reynolds, Paul N ^a,b   Short, Joshua J ^a   Kawakami, Yosuke ^a   Adachi, Yasuo ^a   Glasgow, Joel N ^a   Rots, Marianne G ^a,c   Krasnykh, Victor ^a,d   Douglas, Joanne T ^a,d   Curiel, David T ^a,d  

^a University of Alabama at Birmingham   (United States)

^b ROYAL ADELAIDE HOSPITAL   (Australia)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Ad3; Ad5; Adenovirus; CAR; Chimeric vector

Indexed keywords

ADENOVIRUS VECTOR;

ARTICLE; CELL LINE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MOSAIC VIRUS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SEROTYPE; VIRAL GENE THERAPY; VIRION; VIRUS ADSORPTION; VIRUS INFECTION; WESTERN BLOTTING;

ADENOVIRIDAE;

EID: 0037903340     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6822(03)00067-9     Document Type: Article

References (42)

1. Adachi Y., Reynolds P.N., Yamamoto M., Wang M., Takayama K., Matsubara S., Muramatsu T., Curiel D.T. A midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging. Cancer Res. 61:2001;7882-7888.
2. Bergelson J.M., Cunningham J.A., Droguett G., Kurt-Jones E.A., Krithivas A., Hong J.S., Horwitz M.S., Crowell R.L., Finberg R.W. Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5. Science. 275:1997;1320-1323.
3. Cohen C.J., Gaetz J., Ohman T., Bergelson J.M. Multiple regions within the coxsackieviurs and adenovirus receptor cytoplasmic domain are required for basolateral sorting. J. Biol. Chem. 276:2001;25392-25398.
4. Cripe T.P., Dunphy E.J., Holub A., Vasi N.H., Mahller Y.Y., Collins M.H., Snyder J.D., Krasnykh V., Curiel D.T., Wickham T., DeGregori J., Bergelson J.M., Currier M.A. Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells. Cancer Res. 61:2001;2951-2960.
5. Davidoff A.M., Stevenson S.C., McClelland A., Shochat S.J., Vanin E.F. Enhanced neuroblastoma transduction for an improved antitumor vaccine. J. Surg. Res. 83:1999;95-99.
6. Defer C., Belin M.-T., Cailet-boudin M.-L., Boulanger P. Human adenovirus-host cell interactions comparative study with members of subgroups B and C . J. Virol. 64:1990;3661-3673.
7. Dmitriev I., Kashentseva E., Rogers B.E., Krasnykh V., Curiel D.T. Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells. J. Virol. 74:2000;6875-6884.
8. Dmitriev I., Krasnykh V., Miller C.R., Wang M., Kashentseva E., Mikheeva G., Belousova N., Curiel D.T. An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism. J. Virol. 72:1998;9706-9713.
9. Douglas J.T., Rogers B.E., Rosenfeld M.E., Michael S.I., Feng M., Curiel D.T. Targeted gene delivery by tropism-modified adenoviral vectors. Nat. Biotechnol. 14:1996;1574-1578.
10. Fechner H., Wang X., Wang H., Jansen A., Pauschinger M., Scherubl H., Bergelson J.M., Schultheiss H.P., Poller W. Trans-complementation of vector replication versus Coxsackie-adenovirus-receptor overexpression to improve transgene expression in poorly permissive cancer cells. Gene Ther. 7:2000;1954-1968.
11. Freimuth P., Springer K., Berard C., Hainfeld J., Bewley M., Flanagan J. Coxsackievirus and adenovirus receptor amino-terminal immunoglobulin V-related domain binds adenovirus type 2 and fiber knob from adenovirus type 12. J. Virol. 73:1999;1392-1398.
12. Gall J., Kass-Eisler A., Leinwand L., Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes . J. Virol. 70:1996;2116-2123.
13. Gomez-Navarro J., Curiel D.T., Douglas J.T. Gene therapy for cancer. Eur. J. Cancer. 35:1999;867-885.
14. Havenga M.J., Lemckert A.A., Grimbergen J.M., Vogels R., Huisman L.G., Valerio D., Bout A., Quax P.H. Improved adenovirus vectors for infection of cardiovascular tissues. J. Virol. 75:2001;3335-3342.
15. Hemmi S., Geertsen R., Mezzacasa A., Peter I., Dummer R. The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures. Hum. Gene Ther. 9:1998;2363-2373.
16. Henry L.J., Xia D., Wilke M.E., Deisenhofer J., Gerald R.D. Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli. J. Virol. 68:1994;5239-5246.
17. Kaner R.J., Worgall S., Leopold P.L., Stolze E., Milano E., Hidaka C., Ramalingam R., Hackett N.R., Singh R., Bergelson J., Finberg R., Falck-Pedersen E., Crystal R.G. Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor. Am. J. Respir. Cell Mol. Biol. 20:1999;361-370.
18. Kanerva A., Mikheeva G.V., Krasnykh V., Coolidge C.J., Lam J.T., Mahasreshti P.J., Baker S.D., Straughn M., Barnes M.N., Alvarez R.D., Hemminki A., Curiel D.T. Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells. Clin. Cancer Res. 8:2002;275-280.
19. Karayan L., Gay B., Gerfaux J., Boulanger P.A. Oligomerization of recombinant penton base of adenovirus type 2 and its assembly with fiber in baculovirus-infected cells. Virology. 202:1994;782-795.
20. Kelly F.J., Miller C.R., Buchsbaum D.J., Gomez-Navarro J., Barnes M.N., Alvarez R.D., Curiel D.T. Selectivity of TAG-72-targeted adenovirus gene transfer to primary ovarian carcinoma cells versus autologous mesothelial cells in vitro. Clin. Cancer Res. 6:2000;4323-4333.
21. Krasnykh V., Belousova N., Korokhov N., Mikheeva G., Curiel D.T. Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin. J. Virol. 75:2001;4176-4183.
22. Krasnykh V., Dmitriev I., Navarro J.G., Belousova N., Kashentseva E., Xiang J., Douglas J.T., Curiel D.T. Advanced generation adenoviral vectors possess augmented gene transfer efficiency based upon coxsackie adenovirus receptor-independent cellular entry capacity. Cancer Res. 60:2000;6784-6787.
23. Krasnykh V.N., Mikheeva G.V., Douglas J.T., Curiel D.T. Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism. J. Virol. 70:1996;6839-6846.
24. Li Y., Pong R.C., Bergelson J.M., Hall M.C., Sagalowsky A.I., Tseng C.P., Wang Z., Hsieh J.T. Loss of adenoviral receptor expression in human bladder cancer cells a potential impact on the efficacy of gene therapy . Cancer Res. 59:1999;325-330.
25. Louis N., Fender P., Barge A., Kitts P., Chroboczek J. Cell-binding domain of adenovirus serotype 2 fiber. J. Virol. 68:1994;4104-4106.
26. Maizel J.V.J., White O., Scharff M.D. The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. Virology. 36:1968;115-125.
27. Miller C.R., Buchsbaum D.J., Reynolds P.N., Douglas J.T., Gillespie G.Y., Mayo M.S., Raben D., Curiel D.T. Differential susceptibility of primary and established human glioma cells to adenovirus infection targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer . Cancer Res. 58:1998;5738-5748.
28. Mittereder N., March K.L., Trapnell B.C. Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J. Virol. 70:1996;7498-7509.
29. Miyazawa N., Leopold P.L., Hackett N.R., Ferris B., Worgall S., Falck-Pedersen E., Crystal R.G. Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors. J. Virol. 73:1999;6056-6065.
30. Nalbantoglu J., Larochelle N., Wolf E., Karpati G., Lochmuller H., Holland P.C. Muscle-specific overexpression of the adenovirus primary receptor car overcomes low efficiency of gene transfer to mature skeletal muscle. J. Virol. 75:2001;4276-4282.
31. Okegawa T., Li Y., Pong R.C., Bergelson J.M., Zhou J., Hsieh J.T. The dual impact of coxsackie and adenovirus receptor expression on human prostate cancer gene therapy. Cancer Res. 60:2000;5031-5036.
32. Pereboev A., Pereboeva L., Curiel D.T. Phage display of adenovirus type 5 fiber knob as a tool for specific selection and validation. J. Virol. 75:2001;7107-7113.
33. Pickles R.J., McCarty D., Matsui H., Hart P.J., Randell S.H., Boucher R.C. Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer. J. Virol. 72:1998;6014-6023.
34. Roelvink P.W., Lizonova A., Lee J.G., Li Y., Bergelson J.M., Finberg R.W., Brough D.E., Kovesdi I., Wickham T.J. The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F. J. Virol. 72:1998;7909-7915.
35. Seki T., Dmitriev I., Kashentseva E., Takayama K., Rots M.G., Suzuki K., Curiel D.T. Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines. J. Virol. 76:2002;1100-1108.
36. Stevenson S.C., Rollence M., Marshall-Neff J., McClelland A. Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein. J. Virol. 71:1997;4782-4790.
37. Stevenson S.C., Rollence M., White B., Weaver L., McClelland A. Human adenovirus serotypes 3 and 5 bind to two different cellular receptors via the fiber head domain. J. Virol. 69:1995;2850-2857.
38. Tomko R.P., Xu R., Philipson L. HCAR and MCAR, the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc. Natl. Acad. Sci. USA. 94:1997;3352-3356.
39. Van't Hof W., Crystal R.G. Manipulation of the cytoplasmic and transmembrane domains alters cell surface levels of the coxsackie-adenovirus receptor and changes the efficiency of adenovirus infection. Hum. Gene Ther. 12:2001;25-34.
40. Von Seggern D.J., Huang S., Fleck S.K., Stevenson S.C., Nemerow G.R. Adenovirus vector pseudotyping in fiber-expressing cell lines, improved transduction of Epstein-Barr virus-transformed B cells. J. Virol. 74:2000;354-362.
41. Zabner J., Chillon M., Grunst T., Moninger T.O., Davidson B.L., Gregory R., Armentano D. A chimeric type 2 adenovirus vector with a type 17 fiber enhances gene transfer to human airway epithelia. J. Virol. 73:1999;8689-8695.
42. Zabner J., Freimuth P., Puga A., Fabrega A., Welsh M.J. Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection. J. Clin. Invest. 100:1997;1144-1149.