Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial

Cancer Research

Volumn 60, Issue 22, 2000, Pages 6359-6366

  Nemunaitis, John ^a,b   Ganly, Ian ^c   Khuri, Fadlo ^d   Arseneau, James ^e   Kuhn, Joseph ^b   McCarty, Todd ^b   Landers, Stephen ^b   Maples, Phillip ^a   Romel, Larry ^f   Randlev, Britta ^f   Reid, Tony ^f   Kaye, Sam ^c   Kirn, David ^f  

^a Developmental Therapeutics Committee and Co Chair of the Genitourinary Committee   (United States)

^b BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^c BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e Albany Regional Cancer Center   (United States)

^f ONYX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADENOVIRUS; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CYTOPATHOGENIC EFFECT; FEMALE; GENE DELETION; HEAD AND NECK CANCER; HUMAN; HUMORAL IMMUNITY; IN SITU HYBRIDIZATION; MALE; PRIORITY JOURNAL; TISSUE INJURY; TUMOR REGRESSION; VIRUS REPLICATION;

ADENOVIRUS E1B PROTEINS; ADENOVIRUSES, HUMAN; AGED; ANTIBODIES, NEOPLASM; BIOPSY; CARCINOMA, SQUAMOUS CELL; FEMALE; GENES, P53; HEAD AND NECK NEOPLASMS; HUMANS; INJECTIONS, INTRALESIONAL; MALE; MIDDLE AGED; MUTATION; NEOPLASM RECURRENCE, LOCAL; VIRUS REPLICATION;

EID: 0033693231     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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