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Volumn 12, Issue 11, 2005, Pages 911-917

Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression

Author keywords

Adenovirus; Hypoxia; Translation

Indexed keywords

ADENOVIRUS VECTOR; CELL PROTEIN; E1A PROTEIN; MESSENGER RNA; VIRUS PROTEIN;

EID: 20744460916     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302459     Document Type: Article
Times cited : (79)

References (32)
  • 1
    • 0034077666 scopus 로고    scopus 로고
    • Replication-selective adenoviruses as oncolytic agents
    • Heise C, Kirn DH. Replication-selective adenoviruses as oncolytic agents. J Clin Invest 2000; 105: 847-851.
    • (2000) J. Clin. Invest. , vol.105 , pp. 847-851
    • Heise, C.1    Kirn, D.H.2
  • 2
    • 0036161443 scopus 로고    scopus 로고
    • Oncolytic biotherapy: A novel therapeutic platform
    • Hawkins LK, Lemoine NR, Kirn D. Oncolytic biotherapy: a novel therapeutic platform. Lancet Oncol 2002; 3: 17-26.
    • (2002) Lancet Oncol. , vol.3 , pp. 17-26
    • Hawkins, L.K.1    Lemoine, N.R.2    Kirn, D.3
  • 3
    • 0036147402 scopus 로고    scopus 로고
    • Assessment of adenoviral vector safety and toxicity: Report of the National Institutes of Health Recombinant DNA Advisory Committee
    • Assessment of adenoviral vector safety and toxicity: report of the National Institutes of Health Recombinant DNA Advisory Committee. Hum Gene Ther 2002; 13: 3-13.
    • (2002) Hum. Gene Ther. , vol.13 , pp. 3-13
  • 4
    • 0034917855 scopus 로고    scopus 로고
    • Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved - Deletion of the viral E1b-19-kD gene increases the viral oncolytic effect
    • Harrison D et al. Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved - deletion of the viral E1b-19-kD gene increases the viral oncolytic effect. Hum Gene Ther 2001; 12: 1323-1332.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 1323-1332
    • Harrison, D.1
  • 5
    • 0034086730 scopus 로고    scopus 로고
    • Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein
    • Doronin K et al. Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein. J Virol 2000; 74: 6147-6155.
    • (2000) J. Virol. , vol.74 , pp. 6147-6155
    • Doronin, K.1
  • 6
    • 0037457032 scopus 로고    scopus 로고
    • Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: Virus persists and spreads systemically at late time points
    • Sauthoff H et al. Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: virus persists and spreads systemically at late time points. Hum Gene Ther 2003; 14: 425-433.
    • (2003) Hum. Gene Ther. , vol.14 , pp. 425-433
    • Sauthoff, H.1
  • 7
    • 0031666742 scopus 로고    scopus 로고
    • The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F
    • Roelvink PW et al. The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F. J Virol 1998; 72: 7909-7915.
    • (1998) J. Virol. , vol.72 , pp. 7909-7915
    • Roelvink, P.W.1
  • 8
    • 0036710714 scopus 로고    scopus 로고
    • The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells
    • Kim M et al. The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells. Eur J Cancer 2002; 38: 1917-1926.
    • (2002) Eur. J. Cancer , vol.38 , pp. 1917-1926
    • Kim, M.1
  • 9
    • 0036644845 scopus 로고    scopus 로고
    • Expression of the coxsackie adenovirus receptor in normal prostate and in primary and metastatic prostate carcinoma: Potential relevance to gene therapy
    • Rauen KA et al. Expression of the coxsackie adenovirus receptor in normal prostate and in primary and metastatic prostate carcinoma: potential relevance to gene therapy. Cancer Res 2002; 62: 3812-3818.
    • (2002) Cancer Res. , vol.62 , pp. 3812-3818
    • Rauen, K.A.1
  • 10
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
    • Hockel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001; 93: 266-276.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 266-276
    • Hockel, M.1    Vaupel, P.2
  • 12
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown JM, Wilson WR. Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 2004; 4: 437-447.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 13
    • 0036173591 scopus 로고    scopus 로고
    • Hypoxia as a target for combined modality treatments
    • Wouters BG et al. Hypoxia as a target for combined modality treatments. Eur J Cancer 2002; 38: 240-257.
    • (2002) Eur. J. Cancer , vol.38 , pp. 240-257
    • Wouters, B.G.1
  • 14
    • 2542450917 scopus 로고    scopus 로고
    • HIF hydroxylation and cellular oxygen sensing
    • Metzen E, Ratcliffe PJ. HIF hydroxylation and cellular oxygen sensing. Biol Chem 2004; 385: 223-230.
    • (2004) Biol. Chem. , vol.385 , pp. 223-230
    • Metzen, E.1    Ratcliffe, P.J.2
  • 15
    • 0003354726 scopus 로고    scopus 로고
    • Adenoviridae and their replication
    • Fields BN, Knipe DM (eds). Lippincott Williams & Wilkins: New York
    • Horwitz MS. Adenoviridae and their replication. In: Fields BN, Knipe DM (eds). Virology. Lippincott Williams & Wilkins: New York, 2001, pp 2301-2326.
    • (2001) Virology , pp. 2301-2326
    • Horwitz, M.S.1
  • 16
    • 0037214282 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia
    • Goda N et al. Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia. Mol Cell Biol 2003; 23: 359-369.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 359-369
    • Goda, N.1
  • 17
    • 0035896558 scopus 로고    scopus 로고
    • Hypoxia inhibits G1/S transition through regulation of p27 expression
    • Gardner LB et al. Hypoxia inhibits G1/S transition through regulation of p27 expression. J Biol Chem 2001; 276: 7919-7926.
    • (2001) J. Biol. Chem. , vol.276 , pp. 7919-7926
    • Gardner, L.B.1
  • 18
    • 0344197968 scopus 로고    scopus 로고
    • Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a
    • Gardner LB, Li F, Yang X, Dang CV. Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a. Mol Cell Biol 2003; 23: 9032-9045.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 9032-9045
    • Gardner, L.B.1    Li, F.2    Yang, X.3    Dang, C.V.4
  • 19
    • 0032838679 scopus 로고    scopus 로고
    • Roles for the E4 orf6, orf3, and E1B 55-kiloDalton proteins in cell cycle-independent adenovirus replication
    • Goodrum ED, Ornelles DA. Roles for the E4 orf6, orf3, and E1B 55-kiloDalton proteins in cell cycle-independent adenovirus replication. J Virol 1999; 73: 7474-7488.
    • (1999) J. Virol. , vol.73 , pp. 7474-7488
    • Goodrum, E.D.1    Ornelles, D.A.2
  • 20
    • 0031060333 scopus 로고    scopus 로고
    • The early region 1B 55-kiloDalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle
    • Goodrum FD, Ornelles DA. The early region 1B 55-kiloDalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle. J Virol 1997; 71: 548-561.
    • (1997) J. Virol. , vol.71 , pp. 548-561
    • Goodrum, F.D.1    Ornelles, D.A.2
  • 21
    • 0029074864 scopus 로고
    • Regulation of protein synthesis in human cells exposed to extreme hypoxia
    • Kraggerud SM, Sandvik JA, Pettersen EO. Regulation of protein synthesis in human cells exposed to extreme hypoxia. Anticancer Res 1995; 15: 683-686.
    • (1995) Anticancer Res. , vol.15 , pp. 683-686
    • Kraggerud, S.M.1    Sandvik, J.A.2    Pettersen, E.O.3
  • 22
    • 0036837864 scopus 로고    scopus 로고
    • Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
    • Koumenis C et al. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. Mol Cell Biol 2002; 22: 7405-7416.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 7405-7416
    • Koumenis, C.1
  • 23
    • 0042031047 scopus 로고    scopus 로고
    • A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets
    • Arsham AM, Howell JJ, Simon MC. A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets. J Biol Chem 2003; 278: 29655-29660.
    • (2003) J. Biol. Chem. , vol.278 , pp. 29655-29660
    • Arsham, A.M.1    Howell, J.J.2    Simon, M.C.3
  • 24
    • 0034722892 scopus 로고    scopus 로고
    • Replication-selective oncolytic adenoviruses: Virotherapy aimed at genetic targets in cancer
    • Kirn D. Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer. Oncogene 2000; 19: 6660-6669.
    • (2000) Oncogene , vol.19 , pp. 6660-6669
    • Kirn, D.1
  • 26
    • 0025370654 scopus 로고
    • Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis
    • Howe JA et al. Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis. Proc Natl Acad Sci USA 1990; 87: 5883-5887.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5883-5887
    • Howe, J.A.1
  • 27
    • 0037333760 scopus 로고    scopus 로고
    • Translation initiation and viral tricks
    • Schneider RJ, Mohr I. Translation initiation and viral tricks. Trends Biochem Sci 2003; 28: 130-136.
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 130-136
    • Schneider, R.J.1    Mohr, I.2
  • 28
    • 3142724909 scopus 로고    scopus 로고
    • Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kiloDalton protein
    • Cuesta R, Xi Q, Schneider RJ. Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kiloDalton protein. J Virol 2004; 78: 7707-7716.
    • (2004) J. Virol. , vol.78 , pp. 7707-7716
    • Cuesta, R.1    Xi, Q.2    Schneider, R.J.3
  • 29
    • 0028879804 scopus 로고
    • DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309
    • Bett AJ, Krougliak V, Graham FL. DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309. Virus Res 1995; 39: 75-82.
    • (1995) Virus Res. , vol.39 , pp. 75-82
    • Bett, A.J.1    Krougliak, V.2    Graham, F.L.3
  • 30
    • 0029315806 scopus 로고
    • Methods for construction of adenovirus vectors
    • Graham FL, Prevec L. Methods for construction of adenovirus vectors. Mol Biotechnol 1995; 3: 207-220.
    • (1995) Mol. Biotechnol. , vol.3 , pp. 207-220
    • Graham, F.L.1    Prevec, L.2
  • 31
    • 0029836780 scopus 로고    scopus 로고
    • Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy
    • Mittereder N, March KL, Trapnell BC. Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J Virol 1996; 70: 7498-7509.
    • (1996) J. Virol. , vol.70 , pp. 7498-7509
    • Mittereder, N.1    March, K.L.2    Trapnell, B.C.3
  • 32
    • 0034628552 scopus 로고    scopus 로고
    • Deletion of the adenoviral E1b-19 kD gene enhances tumor cell killing of a replicating adenoviral vector
    • Sauthoff H, Heitner S, Rom WN, Hay JG. Deletion of the adenoviral E1b-19 kD gene enhances tumor cell killing of a replicating adenoviral vector. Hum Gene Ther 2000; 11: 379-388.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 379-388
    • Sauthoff, H.1    Heitner, S.2    Rom, W.N.3    Hay, J.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.