Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway

Gene Therapy

Volumn 9, Issue 4, 2002, Pages 270-281

  Fuerer, C ^a   Iggo, R ^a  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

APC; Beta catenin; Colon cancer; E1A; Oncolytic adenovirus; Tcf

Indexed keywords

ADENOVIRUS VECTOR; BETA CATENIN; PROTEIN P300; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN; WNT PROTEIN;

ARTICLE; BINDING SITE; CELL SELECTION; COLON CANCER; COLON POLYPOSIS; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; GENE CONSTRUCT; GENE MUTATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; TARGET ORGAN; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TUMOR CELL; VIRAL GENE DELIVERY SYSTEM; VIRUS REPLICATION;

ADENOVIRIDAE; DNA VIRUSES;

EID: 0036200352     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301651     Document Type: Article

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