RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection

Journal of Virology

Volumn 73, Issue 6, 1999, Pages 5156-5161

  Vigne, Emmanuelle ^a   Mahfouz, Irene ^a,b   Dedieu, Jean Francois ^a,b   Brie, Anne ^a   Perricaudet, Michel ^a   Yeh, Patrice ^a  

^a CNRS   (France)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; EPITOPE; LIGAND; MONOCLONAL ANTIBODY; MONOMER; POLYPEPTIDE; VIRUS RECEPTOR; VIRUS VECTOR;

ADENOVIRUS 5; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; GENETIC ENGINEERING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PSEUDOMONAS PUTIDA; SMOOTH MUSCLE FIBER; TRANSGENE; VASCULAR SMOOTH MUSCLE; VIRUS CAPSID; VIRUS INFECTION;

EID: 0033061221     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.6.5156-5161.1999     Document Type: Article

References (28)

1. Athapilly, F. K., R. Murali, J. J. Rux, Z. Cai, and R. M. Burnett. 1994. The refined crystal structure of hexon, the major coat protein of adenovirus type 2, at 2.9 A resolution. J. Mol. Biol. 242:430-455.
2. Bergelson, J. M., J. A. Cunningham, G. Droguett, E. A. Kurt-Jones, A. Krithivas, J. S. Hong, M. S. Horwitz, R. L. Crowell, and R. W. Finberg. 1997. Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5. Science 275:1320-1323.
3. Blanche, F. Personal communication.
4. Clayman, G. L., A, K. el-Naggar, S. M. Lippman, Y. C. Henderson, M. Frederick, J. A. Merritt, L. A. Zumstein, T. M. Timmons, T. J. Liu, L. Ginsberg, J. A. Roth, W. K. Hong, P. Bruso, and H. Goepfert. 1998. Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma. J. Clin. Oncol. 16:2221-2232.
5. Crompton, J., C. I. A. Toogood, N. Wallis, and R. T. Hay. 1994. Expression of a foreign epitope on the surface of the adenovirus hexon. J. Gen. Virol. 75: 133-139.
6. Crouzet, J., L. Naudin, C. Orsini, E. Vigne, L. Ferrero, A. Le Roux, P. Benoit, M. Latta, C. Torrent, P. Denèfle, J.-F. Mayaux, M. Perricaudet, and P. Yeh. 1997. Recombinational construction in Escherichia coli of infectious adenoviral genomes. Proc. Natl. Acad. Sci. USA 94:1414-1419.
7. Dedieu, J.-F., and E. Vigne. Unpublished data.
8. Douglas, J. T., B. E. Rogers, M. E. Rosenfeld, S. I. Michael, M. Feng, and D. T. Curiel. 1996. Targeted gene delivery by tropism-modified adenoviral vectors. Nat. Biotechnol. 14:1574-1578.
9. Gahéry-Ségard, H., F. Farace, D. Godfrin, J. Gaston, R. Lengagne, T. Tursz, P. Boulanger, and J.-G. Guillet. 1998. Immune response to recombinant capsid proteins of adenovirus in human: antifiber and anti-penton base antibodies have a synergistic effect on neutralizing activity. J. Virol. 72:2388-2397.
10. Gall, J., A. Kass-Eisler, L. Leinwand, and E. Falck-Pedersen. 1996. Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J. Virol. 70:2116-2123.
11. Hong, J. S., and J. A. Engler. 1996. Domains required for assembly of adenovirus type 2 fiber trimers. J. Virol. 70:7071-7078.
12. Hong, S. S., L. Karayan, J. Tournier, D. T. Curiel, and P. A. Boulanger. 1997. Adenovirus type 5 fiber knob binds to MHC I α2 domain at the surface of human epithelial and B lymphoblastoid cells. EMBO J. 16:2294-2306.
13. Krasnykh, V., I. Dmilriev, G. Mikheeva, C. Ryan Miller, N. Belousova, and D. T. Curiel. 1998. Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob. J. Virol. 72: 1844-1852.
14. Krasnykh, V. N., G. V. Mikheeva, J. T. Douglas, and D. T. Curiel. 1996. Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism. J. Virol. 70:6839-6846.
15. Latta, M. Unpublished results.
16. Pasqualini, R., E. Koivunen, and E. Ruoslahti. 1998. alpha v integrins as receptors for tumor targeting by circulating ligands. Nat. Biotechnol. 15:542-546.
17. Roelvink, P. W., A. Lizonova, J. G. M. Lee, Y. Li, J. M. Bergelson, R. W. Finberg, D. E. Brough, I. Kovesdi, and T. J. Wickham. 1998. The coxsackie-virus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F. J. Virol. 72: 7909-7915.
18. Rogers, B. E., J. T. Douglas, B. A. Sosnowski, W. Ying, G. Pierce, D. J. Buchsbaum, D. Della Manna, A. Baird, and D. T. Curiel. 1998. Enhanced in vivo gene delivery to human ovarian cancer xenografts utilizing a tropismmodified adenovirus vector. Tumor Targeting 3:25-31.
19. Shenk, T. 1996. Adenoviridae: the viruses and their replication, p. 2111-2148. In B. N. Fields, D. M. Knipe, P. M. Howley, et al. (ed.), Virology, 3rd ed. Lippincott-Raven, Philadelphia, Pa.
20. Stevenson, S. C., M. Rollence, J. Marshall-Neff, and A. McLelland. 1997. Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein. J. Virol. 71:4782-4790.
21. Tomko, R. P., R. Xu, and L. Philipson. 1997. HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc. Natl. Acad. Sci. USA 94:3352-3356.
22. Toogood, C. I. A., J. Crompton, and R. T. Hay. 1992. Antipeptide antisera define neutralizing epitopes on the adenovirus hexon. J. Gen. Virol. 73:1429-1435.
23. Tursz, T., A. Le Cesne, P. Baldeyrou, E. Gautier, P. Opolon, C. Schatz, A. Pavirani, M. Courtney, D. Lamy, T. Ragot, P. Saulnier, A. Andremont, R. Monier, M. Perricaudet, and T. Le Chevalier. 1996. Phase I study of a recombinant adenovirus-mediated gene transfer in lung cancer patients. J. Natl. Cancer Inst. 88:1857-1863.
24. van der Werf, S., C. Wychowski, P. Bruneau, B. Blondel, R. Crainic, F. Horodniceanu, and M. Girard. 1983. Localization of a poliovirus type 1 neutralization epitope in viral capsid polypeptide VP1. Proc. Natl. Acad. Sci. USA 80:5080-5084.
25. Wickham, T. J., P. W. Roelvink, D. E. Brough, and I. Kovesdi. 1996. Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types. Nat. Biotechnol. 14:1570-1573.
26. Wickham, T. J., E. Tzeng, L. L. Shears II, P. W. Roelvink, Y. Li, G. M. Lee, D. E. Brough, A. Lizonova, and I. Kovesdi. 1997. Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins. J. Virol. 71:8221-8229.
27. Yeh, P., J. F. Dedieu, C. Orsini, E. Vigne, P. Denèfle, and M. Perricaudet. 1996. Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit. J. Virol. 70:559-565.
28. Zukowski, M. M., D. F. Gaffney, D. Speck, M. Kaufmann, A. Findell, A. Wisecup, and J. P. Lecocq. 1983. Chromogenic identification of genetic regulatory signals in Bacillus subtilis based or expression of a cloned pseudomonas gene. Proc. Natl. Acad. Sci. USA 80:1101-1105.