-
1
-
-
0024234852
-
Suppression of the neoplastic pnenotype by replacement of the RB gene in human cancer cells
-
Huang, H.-J.S. et al. Suppression of the neoplastic pnenotype by replacement of the RB gene in human cancer cells. Science 242, 1563-1566 (1988).
-
(1988)
Science
, vol.242
, pp. 1563-1566
-
-
Huang, H.-J.S.1
-
2
-
-
0028170806
-
The retinoblastoma protein: More than a tumor suppressor
-
Riley, D.J., Lee, E.Y.-H.P. & Lee, W.-H. The retinoblastoma protein: More than a tumor suppressor. Annu. Rev. Cell Biol. 10, 1-29 (1994).
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 1-29
-
-
Riley, D.J.1
Lee, E.Y.-H.P.2
Lee, W.-H.3
-
3
-
-
0025068887
-
Suppression of the tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene
-
Bookstein, R., Shew, J.-Y., Chen, P.-L., Scully, P. & Lee, W.-H. Suppression of the tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene. Science 247, 712-715 (1990).
-
(1990)
Science
, vol.247
, pp. 712-715
-
-
Bookstein, R.1
Shew, J.-Y.2
Chen, P.-L.3
Scully, P.4
Lee, W.-H.5
-
4
-
-
0026355171
-
Intraocular tumor suppression of retinoblastoma gene reconstituted retinoblastoma cells
-
Madreperla, S.A., Whittum-Hudson, J.A., Prendergast, R.A., Chen, P.-L. & Lee, W.-H. Intraocular tumor suppression of retinoblastoma gene reconstituted retinoblastoma cells. Cancer Res. 61, 6381-6384 (1990).
-
(1990)
Cancer Res.
, vol.61
, pp. 6381-6384
-
-
Madreperla, S.A.1
Whittum-Hudson, J.A.2
Prendergast, R.A.3
Chen, P.-L.4
Lee, W.-H.5
-
5
-
-
0027260523
-
Reconstitution of the retinoblastoma gene suppresses the growth of small cell lung carcinoma cells carrying multiple genetic alterations
-
Ookawa, K. et al. Reconstitution of the retinoblastoma gene suppresses the growth of small cell lung carcinoma cells carrying multiple genetic alterations. Oncogene 8, 2175-2181 (1991)
-
(1991)
Oncogene
, vol.8
, pp. 2175-2181
-
-
Ookawa, K.1
-
6
-
-
0026653706
-
Expression of the retinoblastoma gene product in bladder carcinoma cells associates with a low frequency of tumor formation
-
Goodrich, D.W., Chen, Y., Scully, P. & Lee W.-H. Expression of the retinoblastoma gene product in bladder carcinoma cells associates with a low frequency of tumor formation. Cancer Res. 52, 1968-1973 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 1968-1973
-
-
Goodrich, D.W.1
Chen, Y.2
Scully, P.3
Lee, W.-H.4
-
7
-
-
0027398585
-
Tumor suppressor activity of RB and p53 genes in human breast cancer cells
-
Wang, N.P., To, H., Lee, W.-H. & Lee, E.Y.-H.P. Tumor suppressor activity of RB and p53 genes in human breast cancer cells. Oncogene 8, 279-288 (1993).
-
(1993)
Oncogene
, vol.8
, pp. 279-288
-
-
Wang, N.P.1
To, H.2
Lee, W.-H.3
Lee, E.Y.-H.P.4
-
8
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
Lee, E.Y.-H.P. et al. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359, 288-294 (1992).
-
(1992)
Nature
, vol.359
, pp. 288-294
-
-
Lee, E.Y.-H.P.1
-
9
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks, T. et al. Effects of an Rb mutation in the mouse. Nature 359, 295-300 (1992).
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
-
10
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
Clarke, A.R. et al. Requirement for a functional Rb-1 gene in murine development. Nature 359, 328-330 (1992).
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.R.1
-
11
-
-
0028174064
-
A20,+ mice are predisposed to tumors of the pituitary gland with nearly complete penetrance
-
A20,+ mice are predisposed to tumors of the pituitary gland with nearly complete penetrance. Oncogene 9, 1021-1029 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 1021-1029
-
-
Hu, N.1
-
12
-
-
0028136594
-
Cooperative tumorigenic effects of germline mutations in Rb and p53
-
Williams, B.O. et al. Cooperative tumorigenic effects of germline mutations in Rb and p53. Nature Genet. 7, 480-484 (1994).
-
(1994)
Nature Genet.
, vol.7
, pp. 480-484
-
-
Williams, B.O.1
-
13
-
-
0027968207
-
Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathologic consequences
-
Williams, B.O. et al. Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathologic consequences. EMBO J. 13, 4251-4259 (1994).
-
(1994)
EMBO J.
, vol.13
, pp. 4251-4259
-
-
Williams, B.O.1
-
16
-
-
0028902753
-
Cytostatic therapy for vascular proliferate disorders with a constitutively active form of the retinoblastoma gene product
-
Chang, M.W. et al. Cytostatic therapy for vascular proliferate disorders with a constitutively active form of the retinoblastoma gene product. Science 267, 518-522 (1995).
-
(1995)
Science
, vol.267
, pp. 518-522
-
-
Chang, M.W.1
-
17
-
-
0027182579
-
Expression of a retinoblastoma transgene results in dwarf mice
-
Bignon, Y.-J. et al. Expression of a retinoblastoma transgene results in dwarf mice. Genes Dev. 7, 1654-1662 (1993).
-
(1993)
Genes Dev.
, vol.7
, pp. 1654-1662
-
-
Bignon, Y.-J.1
-
18
-
-
0027755976
-
Quantitative effects of the retinoblastoma gene on mouse development and tissue-specific tumorigenesis
-
Chang, C.-Y., Riley, D.J., Lee, E.Y.-H.P. & Lee, W.-H. Quantitative effects of the retinoblastoma gene on mouse development and tissue-specific tumorigenesis. Cell Growth Differ. 4, 1057-1064 (1993).
-
(1993)
Cell Growth Differ.
, vol.4
, pp. 1057-1064
-
-
Chang, C.-Y.1
Riley, D.J.2
Lee, E.Y.-H.P.3
Lee, W.-H.4
-
19
-
-
0027595949
-
The basic science of gene therapy
-
Mulligan, R.C. The basic science of gene therapy. Science 260, 926-932 (1993).
-
(1993)
Science
, vol.260
, pp. 926-932
-
-
Mulligan, R.C.1
-
20
-
-
0026058874
-
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
-
Goodrich, D.W., Wang, N.P., Qian, Y.-W., Lee, E.Y.-H.P. & Lee, W.-H. The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell 67, 293-302 (1991).
-
(1991)
Cell
, vol.67
, pp. 293-302
-
-
Goodrich, D.W.1
Wang, N.P.2
Qian, Y.-W.3
Lee, E.Y.-H.P.4
Lee, W.-H.5
-
21
-
-
0026802989
-
Regulation of retinoblastoma functions by ectopic expression of human cyclins
-
Hinds, P.W. et al. Regulation of retinoblastoma functions by ectopic expression of human cyclins. Cell 70, 993-1006 (1992).
-
(1992)
Cell
, vol.70
, pp. 993-1006
-
-
Hinds, P.W.1
-
22
-
-
0028131540
-
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation
-
Lee, E.Y.-H.P. et al. Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 8, 2008-2021 (1994).
-
(1994)
Genes Dev.
, vol.8
, pp. 2008-2021
-
-
Lee, E.Y.-H.P.1
-
23
-
-
0029050533
-
Deficiency of retinoblastoma protein leads to inappropriate S phase entry, activation of E2F-responsive genes, and apoptosis
-
Almasan, A. et al. Deficiency of retinoblastoma protein leads to inappropriate S phase entry, activation of E2F-responsive genes, and apoptosis. Proc. Natl. Acad. Sci. USA 92, 5436-5440 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5436-5440
-
-
Almasan, A.1
-
24
-
-
0028861428
-
Inhibition of apoptosis by the retinoblastoma gene product
-
Hass-Kogan, D.A. et al. Inhibition of apoptosis by the retinoblastoma gene product. EMBO J. 14, 461-472 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 461-472
-
-
Hass-Kogan, D.A.1
-
25
-
-
0028914946
-
Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins
-
Slark, R.S. et al. Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins. J. Cell Biol. 129, 779-788 (1995).
-
(1995)
J. Cell Biol.
, vol.129
, pp. 779-788
-
-
Slark, R.S.1
-
26
-
-
0029915968
-
Retinoblastoma protein inhibits IFN-γ induced apoptosis
-
Berry, D.E. et al. Retinoblastoma protein inhibits IFN-γ induced apoptosis. Oncogene 12, 1809-1819 (1996).
-
(1996)
Oncogene
, vol.12
, pp. 1809-1819
-
-
Berry, D.E.1
-
27
-
-
0000008685
-
Transauricular hypophysectomy in rats and mice
-
Falconi, G. & Rossi, G.L. Transauricular hypophysectomy in rats and mice. Endocrinology 74, 301-304 (1964).
-
(1964)
Endocrinology
, vol.74
, pp. 301-304
-
-
Falconi, G.1
Rossi, G.L.2
-
28
-
-
9044252959
-
Tyrosine hydroxylase: The initial step in norepinehrine biosynthesis
-
Nagatsu, T., Levitt, M. & Udenfriend, S. Tyrosine hydroxylase: The initial step in norepinehrine biosynthesis. J. Biol. Chem. 239, 2910-2916 (1964).
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2910-2916
-
-
Nagatsu, T.1
Levitt, M.2
Udenfriend, S.3
-
29
-
-
0022391791
-
r 38,000 characteristic of presynaptic vesicles
-
r 38,000 characteristic of presynaptic vesicles. Cell 41, 1017-1028 (1985).
-
(1985)
Cell
, vol.41
, pp. 1017-1028
-
-
Weidenmann, B.1
Francke, W.W.2
-
30
-
-
0023032310
-
Protein p38: An integral membrane protein specific for small vesicles of neurons and neuroendocrine cells
-
Navone, F. et al. Protein p38: An integral membrane protein specific for small vesicles of neurons and neuroendocrine cells. J. Cell Biol. 103, 2511-2527 (1986).
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2511-2527
-
-
Navone, F.1
-
31
-
-
0025355694
-
Two new monoclonal antibodies provide immunohistochemical evidence for the unique biochemical similarity of the mouse globus pallidus, entopeduncular nucleus, and substantia nigra pars reticulata
-
Sousa, R., Hrinya Tannery, N. & Lafer, E.M. Two new monoclonal antibodies provide immunohistochemical evidence for the unique biochemical similarity of the mouse globus pallidus, entopeduncular nucleus, and substantia nigra pars reticulata. Neuroscience 34, 403-410 (1990).
-
(1990)
Neuroscience
, vol.34
, pp. 403-410
-
-
Sousa, R.1
Hrinya Tannery, N.2
Lafer, E.M.3
-
32
-
-
0026637449
-
Characterization of a novel synapse protein. I. Developmental expression and cellular localization of the F1-20 protein and mRNA
-
Sousa R., Hrinya Tannery, N., Zhou, S. & Lafer, E.M. Characterization of a novel synapse protein. I. Developmental expression and cellular localization of the F1-20 protein and mRNA. J. Neurosci. 12, 2130-2143 (1992).
-
(1992)
J. Neurosci.
, vol.12
, pp. 2130-2143
-
-
Sousa, R.1
Hrinya Tannery, N.2
Zhou, S.3
Lafer, E.M.4
-
33
-
-
0002598664
-
Life span and aging patterns
-
(ed. Green, E.L.) McGraw-Hill, New York
-
Russell, E.S. Life span and aging patterns, in Biology of the Laboratory Mouse, 2nd edn. (ed. Green, E.L.) 511-519 (McGraw-Hill, New York, 1966).
-
(1966)
Biology of the Laboratory Mouse, 2nd Edn.
, pp. 511-519
-
-
Russell, E.S.1
-
34
-
-
13344286312
-
Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis
-
Zabner, J. et al. Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis. J. Clin. Invest. 97, 1504-1511 (1996).
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1504-1511
-
-
Zabner, J.1
-
35
-
-
9544244796
-
Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer
-
Roth, J.A. et al. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nature Med. 2, 985-991 (1996).
-
(1996)
Nature Med.
, vol.2
, pp. 985-991
-
-
Roth, J.A.1
-
36
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukaemia cells that is inhibited by interleukin-6
-
Yonish-Rouach, E. et al. Wild-type p53 induces apoptosis of myeloid leukaemia cells that is inhibited by interleukin-6. Nature 352, 345-347 (1991).
-
(1991)
Nature
, vol.352
, pp. 345-347
-
-
Yonish-Rouach, E.1
-
37
-
-
0027109075
-
p53, guardian of the genome
-
Lane, D.P. p53, guardian of the genome. Nature 358, 15-16 (1992).
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
38
-
-
0025934488
-
Molecular genetics of the retinoblastoma suppressor gene
-
Bookstein, R. & Lee, W.-H. Molecular genetics of the retinoblastoma suppressor gene. Crit. Rev. Oncogen. 2, 211-227 (1991).
-
(1991)
Crit. Rev. Oncogen.
, vol.2
, pp. 211-227
-
-
Bookstein, R.1
Lee, W.-H.2
-
39
-
-
0023686773
-
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC
-
Harbour, J.W. et al. Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 241, 353-357 (1988).
-
(1988)
Science
, vol.241
, pp. 353-357
-
-
Harbour, J.W.1
-
40
-
-
0025311341
-
Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer
-
Hensel, C.H. et al. Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer. Cancer Res. 50, 3067-3072 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 3067-3072
-
-
Hensel, C.H.1
-
41
-
-
0028070540
-
RB protein status and clinical correlation for 171 cell lines representing lung cancer, extrapulmonary small cell carcinoma, and mesothelioma
-
Shizmu, E. et al. RB protein status and clinical correlation for 171 cell lines representing lung cancer, extrapulmonary small cell carcinoma, and mesothelioma. Oncogene 9, 2441-2448 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 2441-2448
-
-
Shizmu, E.1
-
43
-
-
0027737463
-
Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis
-
Rich, D.P. et al. Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis. Hum. Gene Ther. 4, 461-476 (1993).
-
(1993)
Hum. Gene Ther.
, vol.4
, pp. 461-476
-
-
Rich, D.P.1
-
44
-
-
0018581742
-
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells
-
Jones, N. & Shenck, T. Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell 17, 683-689 (1979).
-
(1979)
Cell
, vol.17
, pp. 683-689
-
-
Jones, N.1
Shenck, T.2
-
45
-
-
0344487371
-
Structure of the human retinoblastoma gene
-
Hong, F.D. et al. Structure of the human retinoblastoma gene. Proc. Natl. Acad. Sci. USA 86, 5502-5506 (1989).
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5502-5506
-
-
Hong, F.D.1
-
46
-
-
0027251721
-
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit
-
Durfee, T. et al. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7, 555-569 (1993).
-
(1993)
Genes Dev.
, vol.7
, pp. 555-569
-
-
Durfee, T.1
-
47
-
-
0027377867
-
Application of LacZ fusions to post implantation development
-
Bonnerot, C. & Nicolas, J.-F. Application of LacZ fusions to post implantation development. Methods Enzymol. 225, 451-469 (1993).
-
(1993)
Methods Enzymol.
, vol.225
, pp. 451-469
-
-
Bonnerot, C.1
Nicolas, J.-F.2
-
48
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli, Y., Sherman, Y. & Ben-Sasson, S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-507 (1992).
-
(1992)
J. Cell Biol.
, vol.119
, pp. 493-507
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
49
-
-
0025340056
-
Two distinct and frequently mutated regions of the retinoblastoma protein are required for binding to SV40 T antigen
-
Huang, S., Wang, N.P., Tseng, B.Y., Lee, W.-H. & Lee, E.Y.-H.P. Two distinct and frequently mutated regions of the retinoblastoma protein are required for binding to SV40 T antigen. EMBO J. 9, 1815-1822 (1990).
-
(1990)
EMBO J.
, vol.9
, pp. 1815-1822
-
-
Huang, S.1
Wang, N.P.2
Tseng, B.Y.3
Lee, W.-H.4
Lee, E.Y.-H.P.5
|