-
1
-
-
0018727288
-
Terminology in the description of drug-radiation interactions
-
Steel G.G. Terminology in the description of drug-radiation interactions. Int J Radiat Oncol Biol Phys 5 (1979) 1145-1150
-
(1979)
Int J Radiat Oncol Biol Phys
, vol.5
, pp. 1145-1150
-
-
Steel, G.G.1
-
4
-
-
33846708225
-
The concurrent chemoradiation paradigm - general principles
-
Seiwert T.Y., Salama J.K., and Vokes E.E. The concurrent chemoradiation paradigm - general principles. Nat Clin Pract Oncol 4 (2007) 86-100
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 86-100
-
-
Seiwert, T.Y.1
Salama, J.K.2
Vokes, E.E.3
-
5
-
-
0029954120
-
Treatment of cancer with radiation and drugs
-
Tannock I.F. Treatment of cancer with radiation and drugs. J Clin Oncol 14 (1996) 3156-3174
-
(1996)
J Clin Oncol
, vol.14
, pp. 3156-3174
-
-
Tannock, I.F.1
-
6
-
-
0035669024
-
Sensitizers and protectors of radiation and chemotherapy
-
Poggi M.M., Coleman C.N., and Mitchell J.B. Sensitizers and protectors of radiation and chemotherapy. Curr Probl Cancer 25 (2001) 331-411
-
(2001)
Curr Probl Cancer
, vol.25
, pp. 331-411
-
-
Poggi, M.M.1
Coleman, C.N.2
Mitchell, J.B.3
-
7
-
-
33745311283
-
New and emerging radiosensitizers and protectors
-
Spalding A.C., and Lawrence T.S. New and emerging radiosensitizers and protectors. Cancer Invest 24 (2006) 444-456
-
(2006)
Cancer Invest
, vol.24
, pp. 444-456
-
-
Spalding, A.C.1
Lawrence, T.S.2
-
8
-
-
30544450340
-
Tumor radiosensitizers - current status of development of various approaches: report of an International Atomic Energy Agency meeting
-
Horsman M.R., Bohm L., Margison G.P., et al. Tumor radiosensitizers - current status of development of various approaches: report of an International Atomic Energy Agency meeting. Int J Radiat Oncol Biol Phys 64 (2006) 551-561
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.64
, pp. 551-561
-
-
Horsman, M.R.1
Bohm, L.2
Margison, G.P.3
-
9
-
-
0025110301
-
Radiation and chemotherapy sensitizers and protectors
-
Coleman C.N., and Turrisi A.T. Radiation and chemotherapy sensitizers and protectors. Crit Rev Oncol Hematol 10 (1990) 225-252
-
(1990)
Crit Rev Oncol Hematol
, vol.10
, pp. 225-252
-
-
Coleman, C.N.1
Turrisi, A.T.2
-
10
-
-
0036916372
-
Radioprotectants: current status and new directions
-
Grdina D.J., Murley J.S., and Kataoka Y. Radioprotectants: current status and new directions. Oncology 63 Suppl. 2 (2002) 2-10
-
(2002)
Oncology
, vol.63
, Issue.SUPPL. 2
, pp. 2-10
-
-
Grdina, D.J.1
Murley, J.S.2
Kataoka, Y.3
-
11
-
-
0034046590
-
Radioprotection by antioxidants
-
Weiss J.F., and Landauer M.R. Radioprotection by antioxidants. Ann NY Acad Sci 899 (2000) 44-60
-
(2000)
Ann NY Acad Sci
, vol.899
, pp. 44-60
-
-
Weiss, J.F.1
Landauer, M.R.2
-
13
-
-
0016704806
-
Time-resolved oxygen effects in irradiated bacteria and mammalian cells: a rapid-mix study
-
Shenoy M.A., Asquith J.C., Adams G.E., Michael B.D., and Watts M.E. Time-resolved oxygen effects in irradiated bacteria and mammalian cells: a rapid-mix study. Radiat Res 62 (1975) 498-512
-
(1975)
Radiat Res
, vol.62
, pp. 498-512
-
-
Shenoy, M.A.1
Asquith, J.C.2
Adams, G.E.3
Michael, B.D.4
Watts, M.E.5
-
14
-
-
84912802270
-
Fast response methods in the radiation chemistry of lethal damage in intact cells
-
Okada S., Imamura M., Terashima T., and Yamaguchi H. (Eds)
-
Michael B.D., Harrop H.A., and Maughan R.L. Fast response methods in the radiation chemistry of lethal damage in intact cells. In: Okada S., Imamura M., Terashima T., and Yamaguchi H. (Eds). Radiation research (Proceedings of the Sixth International Congress), Tokyo, Japanese Association of Radiation Research (1979) 288-296
-
(1979)
Radiation research (Proceedings of the Sixth International Congress), Tokyo, Japanese Association of Radiation Research
, pp. 288-296
-
-
Michael, B.D.1
Harrop, H.A.2
Maughan, R.L.3
-
15
-
-
0015552058
-
Chemical radiosensitization of hypoxic cells
-
Adams G.E. Chemical radiosensitization of hypoxic cells. Br Med Bull 29 (1973) 48-53
-
(1973)
Br Med Bull
, vol.29
, pp. 48-53
-
-
Adams, G.E.1
-
16
-
-
0017054430
-
Radiosensitization of hypoxic cells in solid tumours
-
Fowler J.F., Adams G.E., and Denekamp J. Radiosensitization of hypoxic cells in solid tumours. Cancer Treat Rev 3 (1976) 227-256
-
(1976)
Cancer Treat Rev
, vol.3
, pp. 227-256
-
-
Fowler, J.F.1
Adams, G.E.2
Denekamp, J.3
-
18
-
-
0029884764
-
Recent developments in the design of bioreductive drugs
-
Denny W.A., Wilson W.R., and Hay M.P. Recent developments in the design of bioreductive drugs. Br J Cancer 74 Suppl. XXVII (1996) S32-S38
-
(1996)
Br J Cancer
, vol.74
, Issue.SUPPL. XXVII
-
-
Denny, W.A.1
Wilson, W.R.2
Hay, M.P.3
-
19
-
-
0035352723
-
Recent advances in bioreductive drug targeting
-
Naylor M.A., and Thomson P. Recent advances in bioreductive drug targeting. Mini Rev Med Chem 1 (2001) 17-29
-
(2001)
Mini Rev Med Chem
, vol.1
, pp. 17-29
-
-
Naylor, M.A.1
Thomson, P.2
-
20
-
-
33645791677
-
Quinone bioreductive prodrugs as delivery agents
-
Jaffar M., Abou-Zeid N., Bai L., et al. Quinone bioreductive prodrugs as delivery agents. Curr Drug Deliv 1 (2004) 345-350
-
(2004)
Curr Drug Deliv
, vol.1
, pp. 345-350
-
-
Jaffar, M.1
Abou-Zeid, N.2
Bai, L.3
-
21
-
-
0035010504
-
Electron transfer and oxidative stress as key factors in the design of drugs selectively active in hypoxia
-
Wardman P. Electron transfer and oxidative stress as key factors in the design of drugs selectively active in hypoxia. Curr Med Chem 8 (2001) 739-761
-
(2001)
Curr Med Chem
, vol.8
, pp. 739-761
-
-
Wardman, P.1
-
22
-
-
33845189883
-
Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4
-
Thomson P., Naylor M.A., Everett S.A., et al. Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4. Mol Cancer Ther 5 (2006) 2886-2894
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2886-2894
-
-
Thomson, P.1
Naylor, M.A.2
Everett, S.A.3
-
24
-
-
2942590732
-
Exploiting tumour hypoxia in cancer treatment
-
Brown J.M., and Wilson W.R. Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 4 (2004) 437-447
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 437-447
-
-
Brown, J.M.1
Wilson, W.R.2
-
25
-
-
21844455567
-
Hypoxia in head and neck cancer: how much, how important?
-
Janssen H.L., Haustermans K.M., Balm A.J., and Begg A.C. Hypoxia in head and neck cancer: how much, how important?. Head Neck 27 (2005) 622-638
-
(2005)
Head Neck
, vol.27
, pp. 622-638
-
-
Janssen, H.L.1
Haustermans, K.M.2
Balm, A.J.3
Begg, A.C.4
-
26
-
-
33750108975
-
Hypoxia in head and neck cancer
-
Isa A.Y., Ward T.H., West C.M.L., Slevin N.J., and Homer J.J. Hypoxia in head and neck cancer. Br J Radiol 79 (2006) 791-798
-
(2006)
Br J Radiol
, vol.79
, pp. 791-798
-
-
Isa, A.Y.1
Ward, T.H.2
West, C.M.L.3
Slevin, N.J.4
Homer, J.J.5
-
27
-
-
33746174301
-
Hypoxia in biology and medicine - the legacy of L H Gray
-
Dendy P.P., and Wardman P. Hypoxia in biology and medicine - the legacy of L H Gray. Br J Radiol 79 (2006) 545-549
-
(2006)
Br J Radiol
, vol.79
, pp. 545-549
-
-
Dendy, P.P.1
Wardman, P.2
-
28
-
-
0018945269
-
An experimental and analytical study of oxygen depletion in stirred cell suspensions
-
Whillans D.W., and Rauth A.M. An experimental and analytical study of oxygen depletion in stirred cell suspensions. Radiat Res 84 (1980) 97-114
-
(1980)
Radiat Res
, vol.84
, pp. 97-114
-
-
Whillans, D.W.1
Rauth, A.M.2
-
29
-
-
0021382389
-
A thin-film culturing technique allowing rapid gas-liquid equilibration (6 sec) with no toxicity to mammalian cells
-
Koch C.J. A thin-film culturing technique allowing rapid gas-liquid equilibration (6 sec) with no toxicity to mammalian cells. Radiat Res 97 (1984) 434-442
-
(1984)
Radiat Res
, vol.97
, pp. 434-442
-
-
Koch, C.J.1
-
30
-
-
0035253334
-
Low-dose hypersensitivity: current status and possible mechanisms
-
Joiner M.C., Marples B., Lambin P., Short S.C., and Turesson I. Low-dose hypersensitivity: current status and possible mechanisms. Int J Radiat Oncol Biol Phys 49 (2001) 379-389
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 379-389
-
-
Joiner, M.C.1
Marples, B.2
Lambin, P.3
Short, S.C.4
Turesson, I.5
-
31
-
-
32044444127
-
Low-dose hyperradiosensitivity of human glioblastoma cell lines in vitro does not translate into improved outcome of ultrafractionated radiotherapy in vivo
-
Krause M., Wohlfarth J., Georgi B., et al. Low-dose hyperradiosensitivity of human glioblastoma cell lines in vitro does not translate into improved outcome of ultrafractionated radiotherapy in vivo. Int J Radiat Biol 81 (2005) 751-758
-
(2005)
Int J Radiat Biol
, vol.81
, pp. 751-758
-
-
Krause, M.1
Wohlfarth, J.2
Georgi, B.3
-
32
-
-
0020357761
-
Survival measurements at low doses: oxygen enhancement ratio
-
Palcic B., Brosing J.W., and Skarsgard L.D. Survival measurements at low doses: oxygen enhancement ratio. Br J Cancer 46 (1982) 980-984
-
(1982)
Br J Cancer
, vol.46
, pp. 980-984
-
-
Palcic, B.1
Brosing, J.W.2
Skarsgard, L.D.3
-
33
-
-
0023005956
-
Radiosensitization of Chinese hamster cells by oxygen and misonidazole at low X-ray doses
-
Watts M.E., Hodgkiss R.J., Jones N.R., and Fowler J.F. Radiosensitization of Chinese hamster cells by oxygen and misonidazole at low X-ray doses. Int J Radiat Biol 50 (1986) 1009-1021
-
(1986)
Int J Radiat Biol
, vol.50
, pp. 1009-1021
-
-
Watts, M.E.1
Hodgkiss, R.J.2
Jones, N.R.3
Fowler, J.F.4
-
34
-
-
0028230157
-
The effect of oxygen on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79-379A cells
-
Marples B., Joiner M.C., and Skov K.A. The effect of oxygen on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79-379A cells. Radiat Res 138 (1994) S17-S20
-
(1994)
Radiat Res
, vol.138
-
-
Marples, B.1
Joiner, M.C.2
Skov, K.A.3
-
35
-
-
34249676952
-
Radiosensitization by nitric oxide at low radiation doses
-
Wardman P., Rothkamm K., Folkes L.K., Woodcock M., and Johnston P.J. Radiosensitization by nitric oxide at low radiation doses. Radiat Res 167 (2007) 475-484
-
(2007)
Radiat Res
, vol.167
, pp. 475-484
-
-
Wardman, P.1
Rothkamm, K.2
Folkes, L.K.3
Woodcock, M.4
Johnston, P.J.5
-
36
-
-
0029976702
-
Clinical results of hypoxic cell radiosensitization from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide
-
Saunders M., and Dische S. Clinical results of hypoxic cell radiosensitization from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide. Br J Cancer 74 Suppl. XXVII (1996) S271-S278
-
(1996)
Br J Cancer
, vol.74
, Issue.SUPPL. XXVII
-
-
Saunders, M.1
Dische, S.2
-
37
-
-
0030069889
-
Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers
-
Overgaard J., and Horsman M.R. Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol 6 (1996) 10-21
-
(1996)
Semin Radiat Oncol
, vol.6
, pp. 10-21
-
-
Overgaard, J.1
Horsman, M.R.2
-
38
-
-
3242670911
-
Hyperbaric oxygen for delayed radiation injuries
-
Feldmeier J.J. Hyperbaric oxygen for delayed radiation injuries. Undersea Hyperb Med 31 (2004) 133-145
-
(2004)
Undersea Hyperb Med
, vol.31
, pp. 133-145
-
-
Feldmeier, J.J.1
-
39
-
-
0036645420
-
Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion
-
Koch C.J., Oprysko P.R., Shuman A.L., Jenkins W.T., Brandt G., and Evans S.M. Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion. Cancer Res 62 (2002) 3626-3629
-
(2002)
Cancer Res
, vol.62
, pp. 3626-3629
-
-
Koch, C.J.1
Oprysko, P.R.2
Shuman, A.L.3
Jenkins, W.T.4
Brandt, G.5
Evans, S.M.6
-
40
-
-
33750870089
-
Evolution of artificial cells using nanobiotechnology of hemoglobin based RBC blood substitute as an example
-
Chang T.M.S. Evolution of artificial cells using nanobiotechnology of hemoglobin based RBC blood substitute as an example. Artif Cells Blood Substit Immobil Biotechnol 34 (2006) 551-556
-
(2006)
Artif Cells Blood Substit Immobil Biotechnol
, vol.34
, pp. 551-556
-
-
Chang, T.M.S.1
-
41
-
-
10644283057
-
Hypoxia and anemia: factors in decreased sensitivity to radiation therapy and chemotherapy?
-
Harrison L., and Blackwell K. Hypoxia and anemia: factors in decreased sensitivity to radiation therapy and chemotherapy?. Oncologist 9 Suppl. 5 (2004) 31-40
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 5
, pp. 31-40
-
-
Harrison, L.1
Blackwell, K.2
-
43
-
-
0036918282
-
Impact of tumor hypoxia and anemia on radiation therapy outcomes
-
Harrison L.B., Chadha M., Hill R.J., Hu K., and Shasha D. Impact of tumor hypoxia and anemia on radiation therapy outcomes. Oncologist 7 (2007) 492-508
-
(2007)
Oncologist
, vol.7
, pp. 492-508
-
-
Harrison, L.B.1
Chadha, M.2
Hill, R.J.3
Hu, K.4
Shasha, D.5
-
44
-
-
0025967266
-
What is the importance of anaemia in radiotherapy? The value of animal studies
-
Hirst D.G. What is the importance of anaemia in radiotherapy? The value of animal studies. Radiother Oncol 20 Suppl. 1 (1991) 29-33
-
(1991)
Radiother Oncol
, vol.20
, Issue.SUPPL. 1
, pp. 29-33
-
-
Hirst, D.G.1
-
45
-
-
0036906874
-
Raising hemoglobin: an opportunity for increasing survival?
-
Thomas G.M. Raising hemoglobin: an opportunity for increasing survival?. Oncology 63 Suppl. 2 (2002) 19-28
-
(2002)
Oncology
, vol.63
, Issue.SUPPL. 2
, pp. 19-28
-
-
Thomas, G.M.1
-
46
-
-
0033212142
-
Novel radiation sensitizers targeting tissue hypoxia
-
Rowinsky E.K. Novel radiation sensitizers targeting tissue hypoxia. Oncology 13 Suppl. 5 (1999) 61-70
-
(1999)
Oncology
, vol.13
, Issue.SUPPL. 5
, pp. 61-70
-
-
Rowinsky, E.K.1
-
48
-
-
33845995467
-
Erythropoietin: effects on life expectancy in patients with cancer-related anaemia
-
Aapro M., and Vaupel P. Erythropoietin: effects on life expectancy in patients with cancer-related anaemia. Curr Med Res Opin 22 Suppl. 4 (2006) 5-13
-
(2006)
Curr Med Res Opin
, vol.22
, Issue.SUPPL. 4
, pp. 5-13
-
-
Aapro, M.1
Vaupel, P.2
-
49
-
-
0026050143
-
In situ tumour radiosensitization induced by clofibrate administration: single dose and fractionated studies
-
Calais G., and Hirst D.G. In situ tumour radiosensitization induced by clofibrate administration: single dose and fractionated studies. Radiother Oncol 22 (1991) 99-103
-
(1991)
Radiother Oncol
, vol.22
, pp. 99-103
-
-
Calais, G.1
Hirst, D.G.2
-
50
-
-
0026785750
-
Allosteric modifiers of hemoglobin: 2-[4-[[(3,5-disubstituted anilino)carbonyl]methyl]phenoxy]-2-methylpropionic acid derivatives that lower the oxygen affinity of hemoglobin in red cell suspensions, in whole blood, and in vivo in rats
-
Abraham D.J., Wireko F.C., Randad R.S., et al. Allosteric modifiers of hemoglobin: 2-[4-[[(3,5-disubstituted anilino)carbonyl]methyl]phenoxy]-2-methylpropionic acid derivatives that lower the oxygen affinity of hemoglobin in red cell suspensions, in whole blood, and in vivo in rats. Biochemistry 31 (1992) 9141-9149
-
(1992)
Biochemistry
, vol.31
, pp. 9141-9149
-
-
Abraham, D.J.1
Wireko, F.C.2
Randad, R.S.3
-
51
-
-
0005855687
-
RSR13, an allosteric effector of haemoglobin, and carbogen radiosensitize FSAII and SCCVII tumours in C3H mice
-
Khandelwal S.R., Kavanagh B.D., Lin P.-S., et al. RSR13, an allosteric effector of haemoglobin, and carbogen radiosensitize FSAII and SCCVII tumours in C3H mice. Br J Cancer 79 (1999) 814-820
-
(1999)
Br J Cancer
, vol.79
, pp. 814-820
-
-
Khandelwal, S.R.1
Kavanagh, B.D.2
Lin, P.-S.3
-
52
-
-
0035120517
-
Allosteric modification of oxygen delivery by hemoglobin
-
Wahr J.A., Gerber M., Venitz J., and Baliga N. Allosteric modification of oxygen delivery by hemoglobin. Anesth Analg 92 (2001) 615-620
-
(2001)
Anesth Analg
, vol.92
, pp. 615-620
-
-
Wahr, J.A.1
Gerber, M.2
Venitz, J.3
Baliga, N.4
-
53
-
-
11344253956
-
Novel radiosensitizers for tumors of the central nervous system
-
Mehta M.P., and Suh J.H. Novel radiosensitizers for tumors of the central nervous system. Curr Opin Investig Drugs 5 (2004) 1284-1291
-
(2004)
Curr Opin Investig Drugs
, vol.5
, pp. 1284-1291
-
-
Mehta, M.P.1
Suh, J.H.2
-
54
-
-
30544446570
-
Radiation sensitization with redox modulators: a promising approach
-
Rosenberg A., and Knox S. Radiation sensitization with redox modulators: a promising approach. Int J Radiat Oncol Biol Phys 64 (2006) 343-354
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.64
, pp. 343-354
-
-
Rosenberg, A.1
Knox, S.2
-
55
-
-
33644520906
-
Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: determinants of response and its prognostic value for subsequent survival
-
Stea B., Suh J.H., Boyd A.P., Cagnoni P.J., Shaw E., and Group R.S. Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: determinants of response and its prognostic value for subsequent survival. Int J Radiat Oncol Biol Phys 64 (2006) 1023-1030
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.64
, pp. 1023-1030
-
-
Stea, B.1
Suh, J.H.2
Boyd, A.P.3
Cagnoni, P.J.4
Shaw, E.5
Group, R.S.6
-
56
-
-
0033764934
-
Pentoxifylline improves the oxygenation and radiation response of BA1112 rat rhabdomyosarcomas and EMT6 mouse mammary carcinomas
-
Collingridge D.R., and Rockwell S. Pentoxifylline improves the oxygenation and radiation response of BA1112 rat rhabdomyosarcomas and EMT6 mouse mammary carcinomas. Int J Cancer 90 (2000) 256-264
-
(2000)
Int J Cancer
, vol.90
, pp. 256-264
-
-
Collingridge, D.R.1
Rockwell, S.2
-
57
-
-
27544461145
-
The role of pentoxifylline as a modifier of radiation therapy
-
Nieder C., Zimmermann F.B., Adam M., and Molls M. The role of pentoxifylline as a modifier of radiation therapy. Cancer Treat Rev 31 (2005) 448-455
-
(2005)
Cancer Treat Rev
, vol.31
, pp. 448-455
-
-
Nieder, C.1
Zimmermann, F.B.2
Adam, M.3
Molls, M.4
-
58
-
-
0025939872
-
A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments
-
Kjellen E., Joiner M.C., Collier J.M., Johns H., and Rojas A. A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments. Radiother Oncol 22 (1991) 81-91
-
(1991)
Radiother Oncol
, vol.22
, pp. 81-91
-
-
Kjellen, E.1
Joiner, M.C.2
Collier, J.M.3
Johns, H.4
Rojas, A.5
-
59
-
-
0025942404
-
Nicotinamide and the hypoxia problem
-
Horsman M.R. Nicotinamide and the hypoxia problem. Radiother Oncol 22 (1991) 79-80
-
(1991)
Radiother Oncol
, vol.22
, pp. 79-80
-
-
Horsman, M.R.1
-
60
-
-
0029932043
-
Nicotinamide as a repair inhibitor in vivo: studies using single and fractionated X-ray doses in mouse skin and kidneys
-
Rojas A., Denekamp J., Johns H., et al. Nicotinamide as a repair inhibitor in vivo: studies using single and fractionated X-ray doses in mouse skin and kidneys. Radiat Res 145 (1996) 419-431
-
(1996)
Radiat Res
, vol.145
, pp. 419-431
-
-
Rojas, A.1
Denekamp, J.2
Johns, H.3
-
61
-
-
0029991291
-
Radiosensitization in normal tissues with oxygen, carbogen or nicotinamide: therapeutic gain comparisons for fractionated X-ray schedules
-
Rojas A., Vojnovic B., Johns H., et al. Radiosensitization in normal tissues with oxygen, carbogen or nicotinamide: therapeutic gain comparisons for fractionated X-ray schedules. Radiother Oncol 39 (1996) 53-64
-
(1996)
Radiother Oncol
, vol.39
, pp. 53-64
-
-
Rojas, A.1
Vojnovic, B.2
Johns, H.3
-
63
-
-
0031282041
-
Accelerated radiotherapy, carbogen and nicotinamide (ARCON) in locally advanced head and neck cancer: a feasibility study
-
Saunders M.I., Hoskin P.J., Pigott K., et al. Accelerated radiotherapy, carbogen and nicotinamide (ARCON) in locally advanced head and neck cancer: a feasibility study. Radiother Oncol 45 (1997) 159-166
-
(1997)
Radiother Oncol
, vol.45
, pp. 159-166
-
-
Saunders, M.I.1
Hoskin, P.J.2
Pigott, K.3
-
64
-
-
0030914416
-
Carbogen and nicotinamide in the treatment of bladder cancer with radical radiotherapy
-
Hoskin P.J., Saunders M.I., Phillips H., et al. Carbogen and nicotinamide in the treatment of bladder cancer with radical radiotherapy. Br J Cancer 76 (1997) 260-263
-
(1997)
Br J Cancer
, vol.76
, pp. 260-263
-
-
Hoskin, P.J.1
Saunders, M.I.2
Phillips, H.3
-
65
-
-
0030890096
-
Administration of nicotinamide during a five to seven week course of radiotherapy: pharmcokinetics, tolerance, and compliance
-
Kaanders J.H.A.M., Stratford M.R.L., Liefers J., et al. Administration of nicotinamide during a five to seven week course of radiotherapy: pharmcokinetics, tolerance, and compliance. Radiother Oncol 43 (1997) 67-73
-
(1997)
Radiother Oncol
, vol.43
, pp. 67-73
-
-
Kaanders, J.H.A.M.1
Stratford, M.R.L.2
Liefers, J.3
-
66
-
-
18844420781
-
Acute and late morbidity in the treatment of advanced bladder carcinoma with accelerated radiotherapy, carbogen, and nicotinamide
-
Hoskin P.J., Rojas A.M., Phillips H., and Saunders M.I. Acute and late morbidity in the treatment of advanced bladder carcinoma with accelerated radiotherapy, carbogen, and nicotinamide. Cancer 103 (2005) 2287-2297
-
(2005)
Cancer
, vol.103
, pp. 2287-2297
-
-
Hoskin, P.J.1
Rojas, A.M.2
Phillips, H.3
Saunders, M.I.4
-
68
-
-
0034194225
-
ARCON: accelerated radiotherapy with carbogen and nicotinamide in head and neck squamous cell carcinomas. The experience of the Cooperative Group of Radiotherapy of the European Organization for Research and Treatment of Cancer (EORTC)
-
Bernier J., Denekamp J., Rojas A., et al. ARCON: accelerated radiotherapy with carbogen and nicotinamide in head and neck squamous cell carcinomas. The experience of the Cooperative Group of Radiotherapy of the European Organization for Research and Treatment of Cancer (EORTC). Radiother Oncol 55 (2000) 111-119
-
(2000)
Radiother Oncol
, vol.55
, pp. 111-119
-
-
Bernier, J.1
Denekamp, J.2
Rojas, A.3
-
69
-
-
29244472455
-
Oxygen-modifying treatment with ARCON reduces the prognostic significance of hemoglobin in squamous cell carcinoma of the head and neck
-
Hoogsteen I.J., Pop L.A.M., Marres H.A.M., et al. Oxygen-modifying treatment with ARCON reduces the prognostic significance of hemoglobin in squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 64 (2006) 83-89
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.64
, pp. 83-89
-
-
Hoogsteen, I.J.1
Pop, L.A.M.2
Marres, H.A.M.3
-
70
-
-
0014541115
-
Electron-affinic sensitization. I. A structural basis for chemical radiosensitizers in bacteria
-
Adams G.E., and Cooke M.S. Electron-affinic sensitization. I. A structural basis for chemical radiosensitizers in bacteria. Int J Radiat Biol 15 (1969) 457-471
-
(1969)
Int J Radiat Biol
, vol.15
, pp. 457-471
-
-
Adams, G.E.1
Cooke, M.S.2
-
71
-
-
0014990685
-
Electron affinic sensitization. Part II: para-nitroacetophenone: a radiosensitizer for anoxic bacterial and mammalian cells
-
Adams G.E., Asquith J.C., Dewey D.L., Foster J.L., Michael B.D., and Willson R.L. Electron affinic sensitization. Part II: para-nitroacetophenone: a radiosensitizer for anoxic bacterial and mammalian cells. Int J Radiat Biol 19 (1971) 575-585
-
(1971)
Int J Radiat Biol
, vol.19
, pp. 575-585
-
-
Adams, G.E.1
Asquith, J.C.2
Dewey, D.L.3
Foster, J.L.4
Michael, B.D.5
Willson, R.L.6
-
72
-
-
0014988943
-
Radiosensitization of mammalian cells by p-nitroacetophenone. I. Characterization in asynchronous and synchronous populations
-
Chapman J.D., Webb R.G., and Borsa J. Radiosensitization of mammalian cells by p-nitroacetophenone. I. Characterization in asynchronous and synchronous populations. Int J Radiat Biol 19 (1971) 561-573
-
(1971)
Int J Radiat Biol
, vol.19
, pp. 561-573
-
-
Chapman, J.D.1
Webb, R.G.2
Borsa, J.3
-
73
-
-
0016243748
-
Metronidazole ('Flagyl'). A radiosensitizer of hypoxic cells
-
Asquith J.C., Foster J.L., Willson R.L., Ings R., and McFadzean J.A. Metronidazole ('Flagyl'). A radiosensitizer of hypoxic cells. Br J Radiol 47 (1974) 474-481
-
(1974)
Br J Radiol
, vol.47
, pp. 474-481
-
-
Asquith, J.C.1
Foster, J.L.2
Willson, R.L.3
Ings, R.4
McFadzean, J.A.5
-
74
-
-
0019864315
-
Hypoxia-mediated drugs for radiation and chemotherapy
-
Adams G.E. Hypoxia-mediated drugs for radiation and chemotherapy. Cancer 48 (1981) 696-707
-
(1981)
Cancer
, vol.48
, pp. 696-707
-
-
Adams, G.E.1
-
75
-
-
0019993528
-
Skin sensitization by misonidazole: a demonstration of uniform mild hypoxia
-
Stewart F.A., Denekamp J., and Randhawa V.S. Skin sensitization by misonidazole: a demonstration of uniform mild hypoxia. Br J Cancer 45 (1982) 869-877
-
(1982)
Br J Cancer
, vol.45
, pp. 869-877
-
-
Stewart, F.A.1
Denekamp, J.2
Randhawa, V.S.3
-
76
-
-
0017882303
-
Sensitization of hypoxic normal tissue
-
Hendry J.H. Sensitization of hypoxic normal tissue. Br J Cancer 37 Suppl. III (1978) 232-234
-
(1978)
Br J Cancer
, vol.37
, Issue.SUPPL. III
, pp. 232-234
-
-
Hendry, J.H.1
-
77
-
-
0021884440
-
Chemical modifiers of radiosensitivity - theory and reality: a review
-
Fowler J.F. Chemical modifiers of radiosensitivity - theory and reality: a review. Int J Radiat Oncol Biol Phys 11 (1985) 665-674
-
(1985)
Int J Radiat Oncol Biol Phys
, vol.11
, pp. 665-674
-
-
Fowler, J.F.1
-
78
-
-
0030926491
-
Cells at intermediate oxygen levels can be more important than the "hypoxic fraction" in determining tumor response to fractionated radiotherapy
-
Wouters B.G., and Brown J.M. Cells at intermediate oxygen levels can be more important than the "hypoxic fraction" in determining tumor response to fractionated radiotherapy. Radiat Res 147 (1997) 541-550
-
(1997)
Radiat Res
, vol.147
, pp. 541-550
-
-
Wouters, B.G.1
Brown, J.M.2
-
79
-
-
0028632781
-
Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors
-
Overgaard J. Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors. Oncol Res 6 (1994) 509-518
-
(1994)
Oncol Res
, vol.6
, pp. 509-518
-
-
Overgaard, J.1
-
80
-
-
0018373569
-
Structure-activity relationships in the development of hypoxic cell radiosensitizers: I. Sensitization efficiency
-
Adams G.E., Clarke E.D., Flockhart I.R., et al. Structure-activity relationships in the development of hypoxic cell radiosensitizers: I. Sensitization efficiency. Int J Radiat Biol 35 (1979) 133-150
-
(1979)
Int J Radiat Biol
, vol.35
, pp. 133-150
-
-
Adams, G.E.1
Clarke, E.D.2
Flockhart, I.R.3
-
81
-
-
0018403488
-
Structure-activity relationships in the development of hypoxic cell radiosensitizers: II. Cytotoxicity and therapeutic ratio
-
Adams G.E., Clarke E.D., Gray P., et al. Structure-activity relationships in the development of hypoxic cell radiosensitizers: II. Cytotoxicity and therapeutic ratio. Int J Radiat Biol 35 (1979) 151-160
-
(1979)
Int J Radiat Biol
, vol.35
, pp. 151-160
-
-
Adams, G.E.1
Clarke, E.D.2
Gray, P.3
-
82
-
-
0025236813
-
Final report of the phase I trial of the hypoxic cell radiosensitizer SR 2508 (etanidazole) Radiation Therapy Oncology Group 83-03
-
Coleman C.N., Wasserman T.H., Urtasun R.C., et al. Final report of the phase I trial of the hypoxic cell radiosensitizer SR 2508 (etanidazole) Radiation Therapy Oncology Group 83-03. Int J Radiat Oncol Biol Phys 18 (1990) 389-393
-
(1990)
Int J Radiat Oncol Biol Phys
, vol.18
, pp. 389-393
-
-
Coleman, C.N.1
Wasserman, T.H.2
Urtasun, R.C.3
-
83
-
-
4243615512
-
Novel (nitro-1-imidazolyl) alkanolamines as potential radiosensitizers with improved therapeutic properties
-
Brady L.W. (Ed), Masson, New York
-
Smithen C.E., Clarke E.D., Dale J.A., et al. Novel (nitro-1-imidazolyl) alkanolamines as potential radiosensitizers with improved therapeutic properties. In: Brady L.W. (Ed). Radiation sensitizers: their use in the clinical management of cancer (1980), Masson, New York 22-32
-
(1980)
Radiation sensitizers: their use in the clinical management of cancer
, pp. 22-32
-
-
Smithen, C.E.1
Clarke, E.D.2
Dale, J.A.3
-
84
-
-
0021860841
-
Cellular uptake of misonidazole and analogues with acidic or basic functions
-
Dennis M.F., Stratford M.R.L., Wardman P., and Watts M.E. Cellular uptake of misonidazole and analogues with acidic or basic functions. Int J Radiat Biol 47 (1985) 629-643
-
(1985)
Int J Radiat Biol
, vol.47
, pp. 629-643
-
-
Dennis, M.F.1
Stratford, M.R.L.2
Wardman, P.3
Watts, M.E.4
-
85
-
-
0025332045
-
Radiosensitization by misonidazole, pimonidazole and azomycin and intracellular uptake in human tumour cell lines
-
Watts M.E., Dennis M.F., and Roberts I.J. Radiosensitization by misonidazole, pimonidazole and azomycin and intracellular uptake in human tumour cell lines. Int J Radiat Biol 57 (1990) 361-372
-
(1990)
Int J Radiat Biol
, vol.57
, pp. 361-372
-
-
Watts, M.E.1
Dennis, M.F.2
Roberts, I.J.3
-
86
-
-
0024324992
-
The uptake of the radiosensitizing compound Ro 03-8799 (pimonidazole) in human tumors
-
Dische S., Bennett M.H., Orchard R., Stratford M.R.L., and Wardman P. The uptake of the radiosensitizing compound Ro 03-8799 (pimonidazole) in human tumors. Int J Radiat Oncol Biol Phys 16 (1989) 1089-1092
-
(1989)
Int J Radiat Oncol Biol Phys
, vol.16
, pp. 1089-1092
-
-
Dische, S.1
Bennett, M.H.2
Orchard, R.3
Stratford, M.R.L.4
Wardman, P.5
-
88
-
-
26444467146
-
Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial
-
Overgaard J., Eriksen J.G., Nordsmark M., Alsner J., Horsman M.R., and Group DHaNCS. Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial. Lancet Oncol 6 (2005) 757-764
-
(2005)
Lancet Oncol
, vol.6
, pp. 757-764
-
-
Overgaard, J.1
Eriksen, J.G.2
Nordsmark, M.3
Alsner, J.4
Horsman, M.R.5
Group DHaNCS6
-
89
-
-
33845351323
-
Design of hypoxia-targeting drugs as new cancer chemotherapeutics
-
Nagasawa H., Uto Y., Kirk K.L., and Hori H. Design of hypoxia-targeting drugs as new cancer chemotherapeutics. Biol Pharm Bull 29 (2006) 2335-2342
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 2335-2342
-
-
Nagasawa, H.1
Uto, Y.2
Kirk, K.L.3
Hori, H.4
-
90
-
-
33144465516
-
Reevaluation of the radiosensitizing effects of sanazole and nimorazole in vitro and in vivo
-
Sugie C., Shibamoto Y., Ito M., et al. Reevaluation of the radiosensitizing effects of sanazole and nimorazole in vitro and in vivo. J Radiat Res (Tokyo) 46 (2005) 453
-
(2005)
J Radiat Res (Tokyo)
, vol.46
, pp. 453
-
-
Sugie, C.1
Shibamoto, Y.2
Ito, M.3
-
91
-
-
33846224376
-
AK-2123 (Sanazol) as a radiation sensitizer in the treatment of stage III cervical cancer: results of an IAEA multicentre randomised trial
-
Dobrowsky W., Huigol N.G., Jayatilake R.S., et al. AK-2123 (Sanazol) as a radiation sensitizer in the treatment of stage III cervical cancer: results of an IAEA multicentre randomised trial. Radiother Oncol 82 (2007) 24-29
-
(2007)
Radiother Oncol
, vol.82
, pp. 24-29
-
-
Dobrowsky, W.1
Huigol, N.G.2
Jayatilake, R.S.3
-
92
-
-
7444255953
-
177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia
-
177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia. Bioorg Med Chem 12 (2004) 6077-6084
-
(2004)
Bioorg Med Chem
, vol.12
, pp. 6077-6084
-
-
Das, T.1
Chakraborty, S.2
Banerjee, S.3
-
93
-
-
33746265277
-
The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON
-
Jonathan R.A., Wijffels K.I.E.M., Peeters W., et al. The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON. Radiother Oncol 79 (2006) 288-297
-
(2006)
Radiother Oncol
, vol.79
, pp. 288-297
-
-
Jonathan, R.A.1
Wijffels, K.I.E.M.2
Peeters, W.3
-
94
-
-
0028839715
-
Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]: analysis of drug adducts by fluorescent antibodies vs. bound radioactivity
-
Koch C.J., Evans S.M., and Lord E.M. Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]: analysis of drug adducts by fluorescent antibodies vs. bound radioactivity. Br J Cancer 72 (1995) 869-874
-
(1995)
Br J Cancer
, vol.72
, pp. 869-874
-
-
Koch, C.J.1
Evans, S.M.2
Lord, E.M.3
-
95
-
-
0035177313
-
Single-photon emission computed tomography and positron-emission tomography assays for tissue oxygenation
-
Chapman J.D., Schneider R.F., Urbain J.L., and Hanks G.E. Single-photon emission computed tomography and positron-emission tomography assays for tissue oxygenation. Semin Radiat Oncol 11 (2001) 47-57
-
(2001)
Semin Radiat Oncol
, vol.11
, pp. 47-57
-
-
Chapman, J.D.1
Schneider, R.F.2
Urbain, J.L.3
Hanks, G.E.4
-
96
-
-
1842587450
-
Phase III trial of radiosensitizer PR-350 combined with intraoperative radiotherapy for the treatment of locally advanced pancreatic cancer
-
Sunamura M., Karasawa K., Okamoto A., et al. Phase III trial of radiosensitizer PR-350 combined with intraoperative radiotherapy for the treatment of locally advanced pancreatic cancer. Pancreas 28 (2004) 330-334
-
(2004)
Pancreas
, vol.28
, pp. 330-334
-
-
Sunamura, M.1
Karasawa, K.2
Okamoto, A.3
-
99
-
-
0040392040
-
Sensitization and protection of oxidative damage caused by high energy radiation
-
Scott G. (Ed), Elsevier, Amsterdam
-
Wardman P. Sensitization and protection of oxidative damage caused by high energy radiation. In: Scott G. (Ed). Atmospheric oxidation and antioxidants Vol. III (1993), Elsevier, Amsterdam 101-127
-
(1993)
Atmospheric oxidation and antioxidants
, vol.III
, pp. 101-127
-
-
Wardman, P.1
-
100
-
-
0032567174
-
Redox dependence of the rate of interaction of hydroxyl radical adducts of DNA nucleobases with oxidants: consequences for DNA strand breakage
-
Bamatraf M.M.M., O'Neill P., and Rao B.S.M. Redox dependence of the rate of interaction of hydroxyl radical adducts of DNA nucleobases with oxidants: consequences for DNA strand breakage. J Am Chem Soc 120 (1998) 11852-11857
-
(1998)
J Am Chem Soc
, vol.120
, pp. 11852-11857
-
-
Bamatraf, M.M.M.1
O'Neill, P.2
Rao, B.S.M.3
-
101
-
-
0344965217
-
Workshop report. DNA targeted hypoxic cytotoxins and radiosensitizers
-
Skov K.A. Workshop report. DNA targeted hypoxic cytotoxins and radiosensitizers. Int J Radiat Biol 56 (1989) 387-393
-
(1989)
Int J Radiat Biol
, vol.56
, pp. 387-393
-
-
Skov, K.A.1
-
103
-
-
0028606213
-
Radiosensitizing and cytotoxic properties of DNA-targeted phenanthridine-linked nitroheterocycles of varying electron affinities
-
Cowan D.S.M., Matejovic J.F., Wardman P., McClelland R.A., and Rauth A.M. Radiosensitizing and cytotoxic properties of DNA-targeted phenanthridine-linked nitroheterocycles of varying electron affinities. Int J Radiat Biol 66 (1994) 729-738
-
(1994)
Int J Radiat Biol
, vol.66
, pp. 729-738
-
-
Cowan, D.S.M.1
Matejovic, J.F.2
Wardman, P.3
McClelland, R.A.4
Rauth, A.M.5
-
104
-
-
0026775234
-
5-Nitro-4-(N,N-dimethylaminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent: comparison with nitracrine
-
Wilson W.R., Siim B.G., Denny W.A., et al. 5-Nitro-4-(N,N-dimethylaminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent: comparison with nitracrine. Radiat Res 131 (1992) 257-265
-
(1992)
Radiat Res
, vol.131
, pp. 257-265
-
-
Wilson, W.R.1
Siim, B.G.2
Denny, W.A.3
-
105
-
-
0027249278
-
Targeting radiosensitizers to DNA by minor groove binding: nitroarenes based on netropsin and distamycin
-
Parrick J., Porssa M., Davies L.K., et al. Targeting radiosensitizers to DNA by minor groove binding: nitroarenes based on netropsin and distamycin. Bioorg Med Chem Lett 3 (1993) 1697-1702
-
(1993)
Bioorg Med Chem Lett
, vol.3
, pp. 1697-1702
-
-
Parrick, J.1
Porssa, M.2
Davies, L.K.3
-
106
-
-
0026596554
-
Uptake and cytotoxicity of novel nitroimidazole-polyamine conjugates in Ehrlich ascites tumour cells
-
Holley J., Mather A., Cullis P., et al. Uptake and cytotoxicity of novel nitroimidazole-polyamine conjugates in Ehrlich ascites tumour cells. Biochem Pharmacol 43 (1992) 763-769
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 763-769
-
-
Holley, J.1
Mather, A.2
Cullis, P.3
-
107
-
-
0024346914
-
A probe for intracellular concentrations of drugs: delayed fluorescence from acridine orange
-
Wardman P., Dennis M.F., and White J. A probe for intracellular concentrations of drugs: delayed fluorescence from acridine orange. Int J Radiat Oncol Biol Phys 16 (1989) 935-938
-
(1989)
Int J Radiat Oncol Biol Phys
, vol.16
, pp. 935-938
-
-
Wardman, P.1
Dennis, M.F.2
White, J.3
-
108
-
-
0024342819
-
Radiosensitizer-DNA interactions in relation to intracellular uptake
-
Stratford M.R.L., Dennis M.F., Watts M.E., Watfa R.R., and Woodcock M. Radiosensitizer-DNA interactions in relation to intracellular uptake. Int J Radiat Oncol Biol Phys 16 (1989) 1007-1010
-
(1989)
Int J Radiat Oncol Biol Phys
, vol.16
, pp. 1007-1010
-
-
Stratford, M.R.L.1
Dennis, M.F.2
Watts, M.E.3
Watfa, R.R.4
Woodcock, M.5
-
109
-
-
0033052663
-
Measurement of extravascular drug diffusion in muticellular layers
-
Wilson W.R., and Hicks K.O. Measurement of extravascular drug diffusion in muticellular layers. Br J Cancer 79 (1999) 1620-1628
-
(1999)
Br J Cancer
, vol.79
, pp. 1620-1628
-
-
Wilson, W.R.1
Hicks, K.O.2
-
110
-
-
0032917763
-
Measurement of delivery and metabolism of tirapazamine to tumour tissue using the mutilayered cell culture model
-
Kyle A.H., and Minchinton A.I. Measurement of delivery and metabolism of tirapazamine to tumour tissue using the mutilayered cell culture model. Cancer Chemother Pharmacol 43 (1999) 213-220
-
(1999)
Cancer Chemother Pharmacol
, vol.43
, pp. 213-220
-
-
Kyle, A.H.1
Minchinton, A.I.2
-
111
-
-
33747443851
-
Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs
-
Hicks K.O., Pruijn F.B., Secomb T.W., et al. Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs. J Natl Cancer Inst 98 (2006) 1118-1128
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1118-1128
-
-
Hicks, K.O.1
Pruijn, F.B.2
Secomb, T.W.3
-
113
-
-
0035254642
-
Therapeutic targets in radiotherapy
-
Brown J.M. Therapeutic targets in radiotherapy. Int J Radiat Oncol Biol Phys 49 (2001) 319-326
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 319-326
-
-
Brown, J.M.1
-
114
-
-
0037105653
-
Tirapazamine: a hypoxia-activated topoisomerase II poison
-
Peters K.B., and Brown J.M. Tirapazamine: a hypoxia-activated topoisomerase II poison. Cancer Res 62 (2002) 5248-5253
-
(2002)
Cancer Res
, vol.62
, pp. 5248-5253
-
-
Peters, K.B.1
Brown, J.M.2
-
115
-
-
0017082617
-
Metronidazole (Flagyl): characterization as a cytotoxic drug specific for hypoxic tumour cells
-
Foster J.L., Conroy P.J., Searle A.J., and Willson R.L. Metronidazole (Flagyl): characterization as a cytotoxic drug specific for hypoxic tumour cells. Br J Cancer 33 (1976) 485-490
-
(1976)
Br J Cancer
, vol.33
, pp. 485-490
-
-
Foster, J.L.1
Conroy, P.J.2
Searle, A.J.3
Willson, R.L.4
-
116
-
-
0017069834
-
Oxygen inhibition of nitroreductase: electron transfer from nitro radical-anions to oxygen
-
Wardman P., and Clarke E.D. Oxygen inhibition of nitroreductase: electron transfer from nitro radical-anions to oxygen. Biochem Biophys Res Commun 69 (1976) 942-949
-
(1976)
Biochem Biophys Res Commun
, vol.69
, pp. 942-949
-
-
Wardman, P.1
Clarke, E.D.2
-
117
-
-
0023929181
-
Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzo-triazine-1,4-dioxide (SR 4233)
-
Laderoute K., Wardman P., and Rauth A.M. Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzo-triazine-1,4-dioxide (SR 4233). Biochem Pharmacol 37 (1988) 1487-1495
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 1487-1495
-
-
Laderoute, K.1
Wardman, P.2
Rauth, A.M.3
-
118
-
-
0025646401
-
Potentiation of the hypoxic cytotoxin SR 4233 of cell killing produced by fractionated irradiation of mouse tumors
-
Brown J.M., and Lemmon M.J. Potentiation of the hypoxic cytotoxin SR 4233 of cell killing produced by fractionated irradiation of mouse tumors. Cancer Res 50 (1990) 7745-7749
-
(1990)
Cancer Res
, vol.50
, pp. 7745-7749
-
-
Brown, J.M.1
Lemmon, M.J.2
-
119
-
-
0029959194
-
The one-electron reduction potential of 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine): a hypoxia-selective bioreductive drug
-
Priyadarsini K.I., Tracy M., and Wardman P. The one-electron reduction potential of 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine): a hypoxia-selective bioreductive drug. Free Radic Res 25 (1996) 393-399
-
(1996)
Free Radic Res
, vol.25
, pp. 393-399
-
-
Priyadarsini, K.I.1
Tracy, M.2
Wardman, P.3
-
120
-
-
0001611802
-
Chemistry of nitroarene and aromatic N-oxide radicals
-
Alfassi Z.B. (Ed), Wiley, New York
-
Wardman P. Chemistry of nitroarene and aromatic N-oxide radicals. In: Alfassi Z.B. (Ed). The chemistry of N-centered radicals (1998), Wiley, New York 615-661
-
(1998)
The chemistry of N-centered radicals
, pp. 615-661
-
-
Wardman, P.1
-
121
-
-
0024363523
-
Pre- and post-irradiation radiosensitization by SR 4233
-
Zeman E.M., and Brown J.M. Pre- and post-irradiation radiosensitization by SR 4233. Int J Radiat Oncol Biol Phys 16 (1989) 967-971
-
(1989)
Int J Radiat Oncol Biol Phys
, vol.16
, pp. 967-971
-
-
Zeman, E.M.1
Brown, J.M.2
-
123
-
-
34248388023
-
Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells
-
Itani W., Geara F., Haykal J., Haddadin M., and Gali-Muhtasib H. Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells. Radiat Oncol 2 (2007) 1-13
-
(2007)
Radiat Oncol
, vol.2
, pp. 1-13
-
-
Itani, W.1
Geara, F.2
Haykal, J.3
Haddadin, M.4
Gali-Muhtasib, H.5
-
124
-
-
0025023154
-
Synthesis and evaluation of a-[[(2-haloethyl)amino]methyl]-2-nitro-1H-imidazole-1-ethanols as prodrugs of a-[(1-aziridinyl)methyl]2-nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogues which are radiosensitizers and bioreductively activated cytotoxins
-
Jenkins T.C., Naylor M.A., O'Neill P., et al. Synthesis and evaluation of a-[[(2-haloethyl)amino]methyl]-2-nitro-1H-imidazole-1-ethanols as prodrugs of a-[(1-aziridinyl)methyl]2-nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogues which are radiosensitizers and bioreductively activated cytotoxins. J Med Chem 33 (1990) 2603-2610
-
(1990)
J Med Chem
, vol.33
, pp. 2603-2610
-
-
Jenkins, T.C.1
Naylor, M.A.2
O'Neill, P.3
-
125
-
-
0026077752
-
A new class of analogues of the bifunctional radiosensitizer a-(1-aziridinylmethyl)2-nitro-1H-imidazole-1-ethanol (RSU 1069): the cycloalkylaziridines
-
Suto M.J., Stier M.A., Werbel L.M., et al. A new class of analogues of the bifunctional radiosensitizer a-(1-aziridinylmethyl)2-nitro-1H-imidazole-1-ethanol (RSU 1069): the cycloalkylaziridines. J Med Chem 34 (1991) 2484-2488
-
(1991)
J Med Chem
, vol.34
, pp. 2484-2488
-
-
Suto, M.J.1
Stier, M.A.2
Werbel, L.M.3
-
126
-
-
0027290844
-
Assessing the bioreductive effectiveness of the nitroimidazole RSU1069 and its prodrug RB6145: with particular reference to in vivo methods of evaluation
-
Bremner J.C.M. Assessing the bioreductive effectiveness of the nitroimidazole RSU1069 and its prodrug RB6145: with particular reference to in vivo methods of evaluation. Cancer Metastasis Rev 12 (1993) 177-193
-
(1993)
Cancer Metastasis Rev
, vol.12
, pp. 177-193
-
-
Bremner, J.C.M.1
-
127
-
-
0030498093
-
A comparison of the physiological effects of RSU1069 and RB6145 in the SCCVII murine tumour
-
Wood P.J., Horsman M.R., Khalil A.A., et al. A comparison of the physiological effects of RSU1069 and RB6145 in the SCCVII murine tumour. Acta Oncol 35 (1996) 989-994
-
(1996)
Acta Oncol
, vol.35
, pp. 989-994
-
-
Wood, P.J.1
Horsman, M.R.2
Khalil, A.A.3
-
128
-
-
20344382293
-
Tirapazamine administered as a neoadjuvant to radiotherapy reduces metastatic dissemination
-
Lunt S.J., Telfer B.A., Fitzmaurice R.J., Stratford I.J., and Williams K.J. Tirapazamine administered as a neoadjuvant to radiotherapy reduces metastatic dissemination. Clin Cancer Res 11 (2005) 4212-4216
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4212-4216
-
-
Lunt, S.J.1
Telfer, B.A.2
Fitzmaurice, R.J.3
Stratford, I.J.4
Williams, K.J.5
-
129
-
-
34347245769
-
-
Ross AB, Mallard WG, Helman WP, Buxton GV, Huie RE, Neta P. NDRL-NIST Solution Kinetics Database: Version 3. Notre Dame, Indiana and Gaithersburg, Maryland: Notre Dame Radiation Laboratory and National Institute of Standards and Technology, 1998.
-
-
-
-
130
-
-
0037188503
-
Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide
-
Shafirovich V., and Lymar S.V. Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide. Proc Natl Acad Sci USA 99 (2002) 7340-7345
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7340-7345
-
-
Shafirovich, V.1
Lymar, S.V.2
-
131
-
-
0026541168
-
Oxygen effect for DNA double-strand break induction determined by pulsed-field gel electrophoresis
-
Whitaker S.J., and McMillan T.J. Oxygen effect for DNA double-strand break induction determined by pulsed-field gel electrophoresis. Int J Radiat Biol 61 (1992) 29-41
-
(1992)
Int J Radiat Biol
, vol.61
, pp. 29-41
-
-
Whitaker, S.J.1
McMillan, T.J.2
-
132
-
-
0028048029
-
Lack of correlation between radiosensitivity and DNA double-strand breaks: induction or rejoining in six human tumor cell lines
-
Olive P.L., Bánath J.P., and MacPhail H.S. Lack of correlation between radiosensitivity and DNA double-strand breaks: induction or rejoining in six human tumor cell lines. Cancer Res 54 (1994) 3939-3946
-
(1994)
Cancer Res
, vol.54
, pp. 3939-3946
-
-
Olive, P.L.1
Bánath, J.P.2
MacPhail, H.S.3
-
133
-
-
0001665005
-
Effect of nitric oxide on the radiosensitivity of bacteria
-
Howard-Flanders P. Effect of nitric oxide on the radiosensitivity of bacteria. Nature 180 (1957) 1191-1192
-
(1957)
Nature
, vol.180
, pp. 1191-1192
-
-
Howard-Flanders, P.1
-
134
-
-
0942264753
-
Effect of nitric oxide on the radiosensitivity of tumour cells
-
Gray L.H., Green F.O., and Hawes C.A. Effect of nitric oxide on the radiosensitivity of tumour cells. Nature 182 (1958) 952-953
-
(1958)
Nature
, vol.182
, pp. 952-953
-
-
Gray, L.H.1
Green, F.O.2
Hawes, C.A.3
-
135
-
-
0027145634
-
Hypoxic mammalian cell radiosensitization by nitric oxide
-
Mitchell J.B., Wink D.A., DeGraff W., Gamson J., Keefer L.K., and Krishna M.C. Hypoxic mammalian cell radiosensitization by nitric oxide. Cancer Res 53 (1993) 5845-5848
-
(1993)
Cancer Res
, vol.53
, pp. 5845-5848
-
-
Mitchell, J.B.1
Wink, D.A.2
DeGraff, W.3
Gamson, J.4
Keefer, L.K.5
Krishna, M.C.6
-
136
-
-
0029990646
-
Radiation sensitization by nitric oxide releasing agents
-
Mitchell J.B., Cook J.A., Krishna M.C., et al. Radiation sensitization by nitric oxide releasing agents. Br J Cancer 74 Suppl. XXVII (1996) S181-S184
-
(1996)
Br J Cancer
, vol.74
, Issue.SUPPL. XXVII
-
-
Mitchell, J.B.1
Cook, J.A.2
Krishna, M.C.3
-
137
-
-
0031742539
-
Redox generation of nitric oxide to radiosensitize hypoxic cells
-
Mitchell J.B., DeGraff W., Kim S., et al. Redox generation of nitric oxide to radiosensitize hypoxic cells. Int J Radiat Oncol Biol Phys 42 (1998) 795-798
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.42
, pp. 795-798
-
-
Mitchell, J.B.1
DeGraff, W.2
Kim, S.3
-
138
-
-
0003764608
-
-
Ignarro L.J. (Ed), Academic Press, San Diego
-
In: Ignarro L.J. (Ed). Nitric oxide. Biology and pathobiology (2000), Academic Press, San Diego
-
(2000)
Nitric oxide. Biology and pathobiology
-
-
-
139
-
-
3242798679
-
Use of the radiation-inducible WAF1 promoter to drive iNOS gene therapy as a novel anti-cancer treatment
-
Worthington J., McCarthy H.O., Barrett E., Adams C., Robson T., and Hirst D.G. Use of the radiation-inducible WAF1 promoter to drive iNOS gene therapy as a novel anti-cancer treatment. J Gene Med 6 (2004) 673-680
-
(2004)
J Gene Med
, vol.6
, pp. 673-680
-
-
Worthington, J.1
McCarthy, H.O.2
Barrett, E.3
Adams, C.4
Robson, T.5
Hirst, D.G.6
-
140
-
-
1242338769
-
Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity
-
Wang Z., Cook T., Alber S., et al. Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity. Cancer Res 64 (2004) 1386-1395
-
(2004)
Cancer Res
, vol.64
, pp. 1386-1395
-
-
Wang, Z.1
Cook, T.2
Alber, S.3
-
141
-
-
7444243914
-
Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53
-
Cook T., Wang Z., Alber S., et al. Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53. Cancer Res 64 (2004) 8015-8021
-
(2004)
Cancer Res
, vol.64
, pp. 8015-8021
-
-
Cook, T.1
Wang, Z.2
Alber, S.3
-
142
-
-
27144458794
-
Evaluation of a synthetic CArG promoter for nitric oxide synthase gene therapy of cancer
-
Worthington J., Robson T., Scott S., and Hirst D. Evaluation of a synthetic CArG promoter for nitric oxide synthase gene therapy of cancer. Gene Ther 12 (2005) 1417-1423
-
(2005)
Gene Ther
, vol.12
, pp. 1417-1423
-
-
Worthington, J.1
Robson, T.2
Scott, S.3
Hirst, D.4
-
143
-
-
33846493140
-
(WAF1)-mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy
-
(WAF1)-mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy. Gene Ther 14 (2007) 246-255
-
(2007)
Gene Ther
, vol.14
, pp. 246-255
-
-
McCarthy, H.O.1
Worthington, J.2
Barrett, E.3
-
144
-
-
0037208614
-
Potentiation of radiation-induced regrowth delay by isosorbide dinitrate in FSAII murine tumors
-
Jordan B.F., Beghein N., Aubry M., Grégoire V., and Gallez B. Potentiation of radiation-induced regrowth delay by isosorbide dinitrate in FSAII murine tumors. Int J Cancer 103 (2003) 138-141
-
(2003)
Int J Cancer
, vol.103
, pp. 138-141
-
-
Jordan, B.F.1
Beghein, N.2
Aubry, M.3
Grégoire, V.4
Gallez, B.5
-
145
-
-
0242586076
-
Nitric oxide-mediated increase in tumor blood flow and oxygenation of tumors implanted in muscles stimulated by electric pulses
-
Jordan B.F., Sonveaux P., Feron O., Grégoire V., Beghein N., and Gallez B. Nitric oxide-mediated increase in tumor blood flow and oxygenation of tumors implanted in muscles stimulated by electric pulses. Int J Radiat Oncol Biol Phys 55 (2003) 1066-1073
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.55
, pp. 1066-1073
-
-
Jordan, B.F.1
Sonveaux, P.2
Feron, O.3
Grégoire, V.4
Beghein, N.5
Gallez, B.6
-
146
-
-
22144456034
-
NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels
-
Kashiwagi S., Izumi Y., Gohongi T., et al. NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels. J Clin Invest 115 (2005) 1816-1827
-
(2005)
J Clin Invest
, vol.115
, pp. 1816-1827
-
-
Kashiwagi, S.1
Izumi, Y.2
Gohongi, T.3
-
147
-
-
0030811240
-
Effects of diethylamine/nitric oxide on blood perfusion and oxygenation in the R3230Ac mammary carcinoma
-
Shan S.Q., Rosner G.L., Braun R.D., Hahn J., Pearce C., and Dewhirst M.W. Effects of diethylamine/nitric oxide on blood perfusion and oxygenation in the R3230Ac mammary carcinoma. Br J Cancer 76 (1997) 429-437
-
(1997)
Br J Cancer
, vol.76
, pp. 429-437
-
-
Shan, S.Q.1
Rosner, G.L.2
Braun, R.D.3
Hahn, J.4
Pearce, C.5
Dewhirst, M.W.6
-
148
-
-
40249092194
-
Nitric oxide and tumor biology
-
Lamas S., and Cadenas E. (Eds), CRC Press, Boca Raton
-
Sonveaux P., and Feron O. Nitric oxide and tumor biology. In: Lamas S., and Cadenas E. (Eds). Nitric oxide, cell signaling, and gene expression (2006), CRC Press, Boca Raton 395-420
-
(2006)
Nitric oxide, cell signaling, and gene expression
, pp. 395-420
-
-
Sonveaux, P.1
Feron, O.2
-
149
-
-
5644294776
-
Inhaled nitric oxide. A selective pulmonary vasodilator. Current uses and therapeutic potential
-
Ichinose F., Roberts Jr. J.D., and Zapol W.M. Inhaled nitric oxide. A selective pulmonary vasodilator. Current uses and therapeutic potential. Circulation 109 (2004) 3106-3111
-
(2004)
Circulation
, vol.109
, pp. 3106-3111
-
-
Ichinose, F.1
Roberts Jr., J.D.2
Zapol, W.M.3
-
151
-
-
33846546058
-
Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study
-
Ng Q.-S., Goh V., Milner J., et al. Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study. Lancet Oncol 8 (2007) 111-118
-
(2007)
Lancet Oncol
, vol.8
, pp. 111-118
-
-
Ng, Q.-S.1
Goh, V.2
Milner, J.3
-
152
-
-
2642571660
-
Vascular-targeting therapies for treatment of malignant disease
-
Siemann D.W., Chaplin D.J., and Horsman M.R. Vascular-targeting therapies for treatment of malignant disease. Cancer 100 (2004) 2491-2499
-
(2004)
Cancer
, vol.100
, pp. 2491-2499
-
-
Siemann, D.W.1
Chaplin, D.J.2
Horsman, M.R.3
-
154
-
-
0027175535
-
Limited role of vasculature-mediated injury in tumor response to radiotherapy
-
Denekamp J. Limited role of vasculature-mediated injury in tumor response to radiotherapy. J Natl Cancer Inst 85 (1994) 935-937
-
(1994)
J Natl Cancer Inst
, vol.85
, pp. 935-937
-
-
Denekamp, J.1
-
155
-
-
0031307208
-
Nitric oxide in tumour biology and cancer therapy. Part 2: therapeutic implications
-
Tozer G.M., and Everett S.A. Nitric oxide in tumour biology and cancer therapy. Part 2: therapeutic implications. Clin Oncol (R Coll Radiol) 9 (1997) 357-364
-
(1997)
Clin Oncol (R Coll Radiol)
, vol.9
, pp. 357-364
-
-
Tozer, G.M.1
Everett, S.A.2
-
156
-
-
0030665017
-
Nitric oxide in tumour biology and cancer therapy. Part 1: physiological aspects
-
Tozer G.M., and Everett S.A. Nitric oxide in tumour biology and cancer therapy. Part 1: physiological aspects. Clin Oncol (R Coll Radiol) 9 (1997) 282-293
-
(1997)
Clin Oncol (R Coll Radiol)
, vol.9
, pp. 282-293
-
-
Tozer, G.M.1
Everett, S.A.2
-
157
-
-
0037096740
-
Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption
-
Jordan B.F., Grégoire V., Demeure R.J., et al. Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption. Cancer Res 62 (2002) 3555-3561
-
(2002)
Cancer Res
, vol.62
, pp. 3555-3561
-
-
Jordan, B.F.1
Grégoire, V.2
Demeure, R.J.3
-
158
-
-
33751184377
-
The radiosensitizing effect of immunoadjuvant OM-174 requires cooperation between immune and tumor cells through interferon-gamma and inducible nitric oxide synthase
-
De Ridder M., Verovski V.N., Chiavaroli C., et al. The radiosensitizing effect of immunoadjuvant OM-174 requires cooperation between immune and tumor cells through interferon-gamma and inducible nitric oxide synthase. Int J Radiat Oncol Biol Phys 66 (2006) 1473-1480
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.66
, pp. 1473-1480
-
-
De Ridder, M.1
Verovski, V.N.2
Chiavaroli, C.3
-
159
-
-
33845556689
-
Intramolecular electron transfer and dehalogenation of anion radicals. 2. Halonitroaromatic compounds
-
Behar D., and Neta P. Intramolecular electron transfer and dehalogenation of anion radicals. 2. Halonitroaromatic compounds. J Phys Chem 85 (1981) 690-693
-
(1981)
J Phys Chem
, vol.85
, pp. 690-693
-
-
Behar, D.1
Neta, P.2
-
160
-
-
0031938856
-
Reduction of nitroarylmethyl quaternary ammonium prodrugs of mechloramine by radiation
-
Wilson W.R., Ferry D.M., Tercel M., Anderson R.F., and Denny W.A. Reduction of nitroarylmethyl quaternary ammonium prodrugs of mechloramine by radiation. Radiat Res 149 (1998) 237-245
-
(1998)
Radiat Res
, vol.149
, pp. 237-245
-
-
Wilson, W.R.1
Ferry, D.M.2
Tercel, M.3
Anderson, R.F.4
Denny, W.A.5
-
161
-
-
0036895522
-
Pathways of reductive fragmentation of heterocyclic nitroarylmethyl quaternary ammonium prodrugs of mechlorethamine
-
Kriste A.G., Tercel M., Anderson R.F., Ferry D.M., and Wilson W.R. Pathways of reductive fragmentation of heterocyclic nitroarylmethyl quaternary ammonium prodrugs of mechlorethamine. Radiat Res 158 (2002) 753-762
-
(2002)
Radiat Res
, vol.158
, pp. 753-762
-
-
Kriste, A.G.1
Tercel, M.2
Anderson, R.F.3
Ferry, D.M.4
Wilson, W.R.5
-
162
-
-
4644296027
-
Optimization of the auxiliary ligand shell of cobalt(III)(8-hydroxyquinoline) complexes as model hypoxia-selective radiation-activated prodrugs
-
Ahn G.-O., Ware D.C., Denny W.A., and Wilson W.R. Optimization of the auxiliary ligand shell of cobalt(III)(8-hydroxyquinoline) complexes as model hypoxia-selective radiation-activated prodrugs. Radiat Res 162 (2004) 315-325
-
(2004)
Radiat Res
, vol.162
, pp. 315-325
-
-
Ahn, G.-O.1
Ware, D.C.2
Denny, W.A.3
Wilson, W.R.4
-
163
-
-
33646497001
-
Radiolytic and cellular reduction of a novel hypoxia-activated cobalt(III) prodrug of a chloromethylbenzindoline DNA minor groove alkylator
-
Ahn G.-O., Botting K.J., Patterson A.V., Ware D.C., Tercel M., and Wilson W.R. Radiolytic and cellular reduction of a novel hypoxia-activated cobalt(III) prodrug of a chloromethylbenzindoline DNA minor groove alkylator. Biochem Pharmacol 71 (2006) 1683-1694
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1683-1694
-
-
Ahn, G.-O.1
Botting, K.J.2
Patterson, A.V.3
Ware, D.C.4
Tercel, M.5
Wilson, W.R.6
-
164
-
-
17144361816
-
Hypoxia-selective activation of 5-fluorodeoxyuridine prodrug possessing indolequinone structure: radiolytic reduction and cytotoxicity characteristics
-
Tanabe K., Makimura Y., Tachi Y., Imagawa-Sato A., and Nishimoto S. Hypoxia-selective activation of 5-fluorodeoxyuridine prodrug possessing indolequinone structure: radiolytic reduction and cytotoxicity characteristics. Bioorg Med Chem Lett 15 (2005) 2321-2324
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 2321-2324
-
-
Tanabe, K.1
Makimura, Y.2
Tachi, Y.3
Imagawa-Sato, A.4
Nishimoto, S.5
-
165
-
-
0942289880
-
In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2-deoxyuridine activated by hypoxic irradiation
-
Shibamoto Y., Tachi T., Tanabe K., Hatta H., and Nishimoto S.-I. In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2-deoxyuridine activated by hypoxic irradiation. Int J Radiat Oncol Biol Phys 58 (2004) 397-402
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 397-402
-
-
Shibamoto, Y.1
Tachi, T.2
Tanabe, K.3
Hatta, H.4
Nishimoto, S.-I.5
-
166
-
-
0003092834
-
Radiosensitization by copper ions, and consequent reversal of the oxygen effect
-
Cramp W.A. Radiosensitization by copper ions, and consequent reversal of the oxygen effect. Nature 206 (1965) 636-637
-
(1965)
Nature
, vol.206
, pp. 636-637
-
-
Cramp, W.A.1
-
167
-
-
0017819658
-
Copper as a hypoxic cell sensitizer of mammalian cells
-
Hesslewood I.P., Cramp W.A., McBrien D.C.H., Williamson P., and Lott K.A.K. Copper as a hypoxic cell sensitizer of mammalian cells. Br J Cancer 37 Suppl. III (1978) 95-97
-
(1978)
Br J Cancer
, vol.37
, Issue.SUPPL. III
, pp. 95-97
-
-
Hesslewood, I.P.1
Cramp, W.A.2
McBrien, D.C.H.3
Williamson, P.4
Lott, K.A.K.5
-
168
-
-
34347243362
-
-
Selvaraj S, Chabita (Saha) K, Chakraborty A, Bhattacharyya SN, Saha A. Influence of copper (II) ions and its derivatives on radiosensitivity of Escherichia coli. Radiat Phys Chem (in press).
-
-
-
-
169
-
-
0029939394
-
Catalytic metals, ascorbate and free radicals: combinations to avoid
-
Buettner G.R., and Jurkiewicz B.A. Catalytic metals, ascorbate and free radicals: combinations to avoid. Radiat Res 145 (1996) 532-541
-
(1996)
Radiat Res
, vol.145
, pp. 532-541
-
-
Buettner, G.R.1
Jurkiewicz, B.A.2
-
170
-
-
0035477031
-
A critical overview of the chemistry of copper-dependent low density lipoprotein oxidation: roles of lipid hydroperoxides, alpha-tocopherol, thiols, and ceruloplasmin
-
Burkitt M.J. A critical overview of the chemistry of copper-dependent low density lipoprotein oxidation: roles of lipid hydroperoxides, alpha-tocopherol, thiols, and ceruloplasmin. Arch Biochem Biophys 394 (2001) 117-135
-
(2001)
Arch Biochem Biophys
, vol.394
, pp. 117-135
-
-
Burkitt, M.J.1
-
171
-
-
0041050783
-
Copper complexes as drugs
-
Berthon G. (Ed), Marcel Dekker, New York
-
Antholine W.E., Byrnes R., and Petering D.H. Copper complexes as drugs. In: Berthon G. (Ed). Handbook of metal-ligand interactions in biological fluids Vol. 2 (1995), Marcel Dekker, New York 1024-1038
-
(1995)
Handbook of metal-ligand interactions in biological fluids
, vol.2
, pp. 1024-1038
-
-
Antholine, W.E.1
Byrnes, R.2
Petering, D.H.3
-
172
-
-
0020054584
-
The kinetics of the reaction of 'anomalous' 4-nitroimidazole radiosensitizers with thiols
-
Wardman P. The kinetics of the reaction of 'anomalous' 4-nitroimidazole radiosensitizers with thiols. Int J Radiat Biol 41 (1982) 231-235
-
(1982)
Int J Radiat Biol
, vol.41
, pp. 231-235
-
-
Wardman, P.1
-
173
-
-
0023252086
-
Redox properties and rate constants in free-radical mediated damage
-
Wardman P., and Clarke E.D. Redox properties and rate constants in free-radical mediated damage. Br J Cancer 55 Suppl. VIII (1987) 172-177
-
(1987)
Br J Cancer
, vol.55
, Issue.SUPPL. VIII
, pp. 172-177
-
-
Wardman, P.1
Clarke, E.D.2
-
174
-
-
0030013113
-
Gadolinium(III) texaphyrin: a tumor selective radiation sensitizer that is detectable by MRI
-
Young S.W., Qing F., Harriman A., et al. Gadolinium(III) texaphyrin: a tumor selective radiation sensitizer that is detectable by MRI. Proc Natl Acad Sci USA 93 (1996) 6610-6615
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6610-6615
-
-
Young, S.W.1
Qing, F.2
Harriman, A.3
-
175
-
-
0033958684
-
Re-evaluating gadolinium(III) texaphyrin as a radiosensitizing agent
-
Bernhard E.J., Mitchell J.B., Deen D., Cardell M., Rosenthal D.I., and Brown J.M. Re-evaluating gadolinium(III) texaphyrin as a radiosensitizing agent. Cancer Res 60 (2000) 86-91
-
(2000)
Cancer Res
, vol.60
, pp. 86-91
-
-
Bernhard, E.J.1
Mitchell, J.B.2
Deen, D.3
Cardell, M.4
Rosenthal, D.I.5
Brown, J.M.6
-
176
-
-
0000051161
-
One-electron reduction and oxidation studies of the radiation sensitizer gadolinium(III) texaphyrin (PCI-0120) and other water soluble metallotexaphyrins
-
Sessler J.L., Tvermoes N.A., Guldi D.M., Mody T.D., and Allen W.E. One-electron reduction and oxidation studies of the radiation sensitizer gadolinium(III) texaphyrin (PCI-0120) and other water soluble metallotexaphyrins. J Phys Chem A 103 (1999) 787-794
-
(1999)
J Phys Chem A
, vol.103
, pp. 787-794
-
-
Sessler, J.L.1
Tvermoes, N.A.2
Guldi, D.M.3
Mody, T.D.4
Allen, W.E.5
-
177
-
-
0035889348
-
Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species
-
Magda D., Lepp C., Gerasimchuk N., et al. Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species. Int J Radiat Oncol Biol Phys 51 (2001) 1025-1036
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 1025-1036
-
-
Magda, D.1
Lepp, C.2
Gerasimchuk, N.3
-
178
-
-
0016290905
-
The redox potential of the system oxygen-superoxide
-
Wood P.M. The redox potential of the system oxygen-superoxide. FEBS Lett 44 (1974) 21-24
-
(1974)
FEBS Lett
, vol.44
, pp. 21-24
-
-
Wood, P.M.1
-
179
-
-
0026016558
-
The reduction potential of benzyl viologen: an important reference compound for oxidant/radical redox couples
-
Wardman P. The reduction potential of benzyl viologen: an important reference compound for oxidant/radical redox couples. Free Radic Res Commun 14 (1991) 57-67
-
(1991)
Free Radic Res Commun
, vol.14
, pp. 57-67
-
-
Wardman, P.1
-
180
-
-
4143066896
-
The emerging role of reactive oxygen species in cancer therapy
-
Renschler M.F. The emerging role of reactive oxygen species in cancer therapy. Eur J Cancer 40 (2004) 1934-1940
-
(2004)
Eur J Cancer
, vol.40
, pp. 1934-1940
-
-
Renschler, M.F.1
-
181
-
-
0141673128
-
Biological chemistry of reactive oxygen and nitrogen and ionizing radiation-induced signal transduction mechanisms
-
Mikkelsen R.B., and Wardman P. Biological chemistry of reactive oxygen and nitrogen and ionizing radiation-induced signal transduction mechanisms. Oncogene 22 (2003) 5734-5754
-
(2003)
Oncogene
, vol.22
, pp. 5734-5754
-
-
Mikkelsen, R.B.1
Wardman, P.2
-
182
-
-
0036804365
-
Preliminary studies of the effects of gadolinium texaphyrin on the growth and radiosensitivity of EMT6 cells in vitro
-
Rockwell S., Donnelly E.T., Liu Y., and Tang L.Q. Preliminary studies of the effects of gadolinium texaphyrin on the growth and radiosensitivity of EMT6 cells in vitro. Int J Radiat Oncol Biol Phys 54 (2002) 536-541
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 536-541
-
-
Rockwell, S.1
Donnelly, E.T.2
Liu, Y.3
Tang, L.Q.4
-
183
-
-
21244436279
-
Effects of motexafin gadolinium on DNA damage and X-ray-induced DNA damage repair, as assessed by the Comet assay
-
Donnelly E.T., Liu Y., Paul T.K., and Rockwell S. Effects of motexafin gadolinium on DNA damage and X-ray-induced DNA damage repair, as assessed by the Comet assay. Int J Radiat Oncol Biol Phys 62 (2004) 1176-1186
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.62
, pp. 1176-1186
-
-
Donnelly, E.T.1
Liu, Y.2
Paul, T.K.3
Rockwell, S.4
-
184
-
-
0035312794
-
Effects of motexafin gadolinium on tumor metabolism and radiation sensitivity
-
Xu S., Zakian K., Thaler H., et al. Effects of motexafin gadolinium on tumor metabolism and radiation sensitivity. Int J Radiat Oncol Biol Phys 49 (2001) 1381
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 1381
-
-
Xu, S.1
Zakian, K.2
Thaler, H.3
-
185
-
-
1842424239
-
Effects of texaphyrins on the oxygenation of EMT6 mouse mammary tumors
-
Donnelly E.T., Liu Y., Fatunmbi Y.O., Lee I., Magda D., and Rockwell S. Effects of texaphyrins on the oxygenation of EMT6 mouse mammary tumors. Int J Radiat Oncol Biol Phys 58 (2004) 1570-1576
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 1570-1576
-
-
Donnelly, E.T.1
Liu, Y.2
Fatunmbi, Y.O.3
Lee, I.4
Magda, D.5
Rockwell, S.6
-
186
-
-
33751181914
-
Motexafin gadolinium: a novel redox active drug for cancer therapy
-
Magda D., and Miller R.A. Motexafin gadolinium: a novel redox active drug for cancer therapy. Semin Cancer Biol 16 (2006) 466-476
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 466-476
-
-
Magda, D.1
Miller, R.A.2
-
187
-
-
10644246037
-
Motexafin gadolinium: a clinical review of a novel radioenhancer for brain tumors
-
Khuntia D., and Mehta M. Motexafin gadolinium: a clinical review of a novel radioenhancer for brain tumors. Expert Rev Anticancer Ther 4 (2004) 981-989
-
(2004)
Expert Rev Anticancer Ther
, vol.4
, pp. 981-989
-
-
Khuntia, D.1
Mehta, M.2
-
188
-
-
33847054651
-
Motexafin gadolinium in the treatment of brain metastases
-
Richards G.M., and Mehta M.P. Motexafin gadolinium in the treatment of brain metastases. Expert Opin Pharmacother 8 (2007) 351-359
-
(2007)
Expert Opin Pharmacother
, vol.8
, pp. 351-359
-
-
Richards, G.M.1
Mehta, M.P.2
-
189
-
-
0024343230
-
Properties and applications of photodynamic therapy
-
Gomer C.J., Rucker N., Ferrario A., and Wong S. Properties and applications of photodynamic therapy. Radiat Res 120 (1989) 1-18
-
(1989)
Radiat Res
, vol.120
, pp. 1-18
-
-
Gomer, C.J.1
Rucker, N.2
Ferrario, A.3
Wong, S.4
-
190
-
-
0042911931
-
On the double role of Photofrin as a photo- and a radio-sensitising agent: a possible new combination therapy for tumours
-
Schaffer M., Schaffer P.M., Hofstetter A., Dühmke E., and Jori G. On the double role of Photofrin as a photo- and a radio-sensitising agent: a possible new combination therapy for tumours. Photochem Photobiol 1 (2002) 438-439
-
(2002)
Photochem Photobiol
, vol.1
, pp. 438-439
-
-
Schaffer, M.1
Schaffer, P.M.2
Hofstetter, A.3
Dühmke, E.4
Jori, G.5
-
191
-
-
18444395885
-
The application of Photofrin II as a sensitizing agent for ionizing radiation - a new approach in tumor therapy?
-
Schaffer M., Ertl-Wagner B., Schaffer P.M., et al. The application of Photofrin II as a sensitizing agent for ionizing radiation - a new approach in tumor therapy?. Curr Med Chem 12 (2005) 1209-1215
-
(2005)
Curr Med Chem
, vol.12
, pp. 1209-1215
-
-
Schaffer, M.1
Ertl-Wagner, B.2
Schaffer, P.M.3
-
192
-
-
33750354860
-
Feasibility of photofrin II as a radiosensitizing agent in solid tumors - preliminary results
-
Schaffer M., Ertl-Wagner B., Schaffer P.M., et al. Feasibility of photofrin II as a radiosensitizing agent in solid tumors - preliminary results. Onkologie 29 (2006) 514-519
-
(2006)
Onkologie
, vol.29
, pp. 514-519
-
-
Schaffer, M.1
Ertl-Wagner, B.2
Schaffer, P.M.3
-
194
-
-
9344235474
-
Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2-deoxyribose
-
Seo Y., Yan T., Schupp J.E., Colussi V., Taylor K.L., and Kinsella T.J. Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2-deoxyribose. Clin Cancer Res 10 (2004) 7520-7528
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7520-7528
-
-
Seo, Y.1
Yan, T.2
Schupp, J.E.3
Colussi, V.4
Taylor, K.L.5
Kinsella, T.J.6
-
195
-
-
0034798687
-
Targeting DNA mismatch repair for radiosensitization
-
Berry S.E., and Kinsella T.J. Targeting DNA mismatch repair for radiosensitization. Semin Radiat Oncol 11 (2001) 300-315
-
(2001)
Semin Radiat Oncol
, vol.11
, pp. 300-315
-
-
Berry, S.E.1
Kinsella, T.J.2
-
197
-
-
0034788543
-
Recent advances in the use of radiosensitizing nucleosides
-
McGinn C.J., and Lawrence T.S. Recent advances in the use of radiosensitizing nucleosides. Semin Radiat Oncol 11 (2001) 270-280
-
(2001)
Semin Radiat Oncol
, vol.11
, pp. 270-280
-
-
McGinn, C.J.1
Lawrence, T.S.2
-
198
-
-
0034797783
-
Improving chemoradiotherapy in rectal cancer
-
Glynne-Jones R., and Debus J. Improving chemoradiotherapy in rectal cancer. Oncologist 6 Suppl. 4 (2001) 29-34
-
(2001)
Oncologist
, vol.6
, Issue.SUPPL. 4
, pp. 29-34
-
-
Glynne-Jones, R.1
Debus, J.2
-
199
-
-
0242578674
-
Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer
-
Zhu A.X., and Willett C.G. Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer. Semin Radiat Oncol 13 (2003) 454-468
-
(2003)
Semin Radiat Oncol
, vol.13
, pp. 454-468
-
-
Zhu, A.X.1
Willett, C.G.2
-
200
-
-
26944442433
-
New radiosensitizing regimens, drugs, prodrugs, and candidates
-
Vallerga A.K., Zarling D.A., and Kinsella T.J. New radiosensitizing regimens, drugs, prodrugs, and candidates. Clin Adv Hematol Oncol 2 (2004) 793-805
-
(2004)
Clin Adv Hematol Oncol
, vol.2
, pp. 793-805
-
-
Vallerga, A.K.1
Zarling, D.A.2
Kinsella, T.J.3
-
202
-
-
0022339758
-
Carboplatin as a potentiator of radiation therapy
-
Douple E.B., Richmond R.C., O'Hara J.A., and Coughlin C.T. Carboplatin as a potentiator of radiation therapy. Cancer Treat Rev 12 Suppl. A (1985) 111-124
-
(1985)
Cancer Treat Rev
, vol.12
, Issue.SUPPL. A
, pp. 111-124
-
-
Douple, E.B.1
Richmond, R.C.2
O'Hara, J.A.3
Coughlin, C.T.4
-
203
-
-
0028820421
-
Enhanced radiation-induced cell killing by carboplatin in cells of repair-proficient and repair-deficient cell lines
-
Yang L., Douple E.B., O'Hara J.A., Crabtree R.A., and Eastman A. Enhanced radiation-induced cell killing by carboplatin in cells of repair-proficient and repair-deficient cell lines. Radiat Res 144 (1995) 230-236
-
(1995)
Radiat Res
, vol.144
, pp. 230-236
-
-
Yang, L.1
Douple, E.B.2
O'Hara, J.A.3
Crabtree, R.A.4
Eastman, A.5
-
204
-
-
0029088808
-
Production of DNA double-strand breaks by interactions between carboplatin and radiation: a potential mechanism for radiopotentiation
-
Yang L.X., Douple E.B., O'Hara J.A., and Wang H.J. Production of DNA double-strand breaks by interactions between carboplatin and radiation: a potential mechanism for radiopotentiation. Radiat Res 143 (1995) 309-315
-
(1995)
Radiat Res
, vol.143
, pp. 309-315
-
-
Yang, L.X.1
Douple, E.B.2
O'Hara, J.A.3
Wang, H.J.4
-
205
-
-
0023543409
-
3)(Sensitizer)]: radiosensitization and toxicity studies in vitro
-
3)(Sensitizer)]: radiosensitization and toxicity studies in vitro. Radiat Res 112 (1987) 273-282
-
(1987)
Radiat Res
, vol.112
, pp. 273-282
-
-
Skov, K.A.1
Farrell, N.P.2
Adomat, H.3
-
206
-
-
0023608491
-
Modification of radiation response by metal complexes: a review with emphasis on nonplatinum studies
-
Skov K.A. Modification of radiation response by metal complexes: a review with emphasis on nonplatinum studies. Radiat Res 112 (1987) 217-242
-
(1987)
Radiat Res
, vol.112
, pp. 217-242
-
-
Skov, K.A.1
-
207
-
-
0023187091
-
Further studies on toxic and radiosensitizing properties of ruthenium complexes of 4-nitroimidazoles
-
Chan P.K.L., Skov K.A., and James B.R. Further studies on toxic and radiosensitizing properties of ruthenium complexes of 4-nitroimidazoles. Int J Radiat Biol 52 (1987) 49-55
-
(1987)
Int J Radiat Biol
, vol.52
, pp. 49-55
-
-
Chan, P.K.L.1
Skov, K.A.2
James, B.R.3
-
208
-
-
33645726878
-
Chemoradiation paradigm for the treatment of lung cancer
-
Eberhardt W., Pöttgen C., and Stuschke M. Chemoradiation paradigm for the treatment of lung cancer. Nat Clin Pract Oncol 3 (2006) 188-199
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 188-199
-
-
Eberhardt, W.1
Pöttgen, C.2
Stuschke, M.3
-
209
-
-
29244448687
-
Platinum-based concurrent chemoradiotherapy for tumors of the head and neck and the esophagus
-
Hao D., Ritter M.A., Oliver T., and Browman G.P. Platinum-based concurrent chemoradiotherapy for tumors of the head and neck and the esophagus. Semin Radiat Oncol 18 (2006) 10-19
-
(2006)
Semin Radiat Oncol
, vol.18
, pp. 10-19
-
-
Hao, D.1
Ritter, M.A.2
Oliver, T.3
Browman, G.P.4
-
210
-
-
0034517127
-
Cellular and molecular responses to topoisomerase I poisons. Exploiting synergy for improved radiotherapy
-
Miyamoto S., Huang T.T., Würzberger-Davis S., et al. Cellular and molecular responses to topoisomerase I poisons. Exploiting synergy for improved radiotherapy. Ann N Y Acad Sci 922 (2000) 274-292
-
(2000)
Ann N Y Acad Sci
, vol.922
, pp. 274-292
-
-
Miyamoto, S.1
Huang, T.T.2
Würzberger-Davis, S.3
-
211
-
-
2442537264
-
Enhancement of radiotherapy with DNA topoisomerase I-targeted drugs
-
Chen A.Y., Chou R., Shih S.-J., Laub D., and Gandara D. Enhancement of radiotherapy with DNA topoisomerase I-targeted drugs. Crit Rev Oncol Hematol 50 (2004) 111-119
-
(2004)
Crit Rev Oncol Hematol
, vol.50
, pp. 111-119
-
-
Chen, A.Y.1
Chou, R.2
Shih, S.-J.3
Laub, D.4
Gandara, D.5
-
212
-
-
27144450533
-
Ku86 modulates DNA topoisomerase I-mediated radiosensitization, but not cytotoxicity, in mammalian cells
-
Shih S.J., Erbele T., and Chen A.Y. Ku86 modulates DNA topoisomerase I-mediated radiosensitization, but not cytotoxicity, in mammalian cells. Cancer Res 65 (2005) 9194-9199
-
(2005)
Cancer Res
, vol.65
, pp. 9194-9199
-
-
Shih, S.J.1
Erbele, T.2
Chen, A.Y.3
-
213
-
-
1642579676
-
The role of topotecan in the treatment of brain metastases
-
Wong E.T., and Berkenblit A. The role of topotecan in the treatment of brain metastases. Oncologist 9 (2004) 68-79
-
(2004)
Oncologist
, vol.9
, pp. 68-79
-
-
Wong, E.T.1
Berkenblit, A.2
-
214
-
-
0034029002
-
Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent
-
Patterson L.H., McKeown S.R., Ruparelia K., et al. Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent. Br J Cancer 82 (2000) 1984-1990
-
(2000)
Br J Cancer
, vol.82
, pp. 1984-1990
-
-
Patterson, L.H.1
McKeown, S.R.2
Ruparelia, K.3
-
215
-
-
20444413993
-
A cytochrome P450 2B6 meditated gene therapy strategy to enhance the effects of radiation or cyclophosphamide when combined with the bioreductive drug AQ4N
-
McErlane V., Yakkundi A., McCarthy H.O., et al. A cytochrome P450 2B6 meditated gene therapy strategy to enhance the effects of radiation or cyclophosphamide when combined with the bioreductive drug AQ4N. J Gene Med 7 (2005) 851-859
-
(2005)
J Gene Med
, vol.7
, pp. 851-859
-
-
McErlane, V.1
Yakkundi, A.2
McCarthy, H.O.3
-
216
-
-
29344470775
-
Novel radiation-enhancing agents in malignant gliomas
-
Zhang M., and Chakravarti A. Novel radiation-enhancing agents in malignant gliomas. Semin Radiat Oncol 16 (2006) 29-37
-
(2006)
Semin Radiat Oncol
, vol.16
, pp. 29-37
-
-
Zhang, M.1
Chakravarti, A.2
-
217
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virág L., and Szabó C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54 (2002) 375-429
-
(2002)
Pharmacol Rev
, vol.54
, pp. 375-429
-
-
Virág, L.1
Szabó, C.2
-
218
-
-
10744226451
-
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361
-
Calabrese C.R., Almassy R., Barton S., et al. Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. J Natl Cancer Inst 96 (2004) 56-67
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 56-67
-
-
Calabrese, C.R.1
Almassy, R.2
Barton, S.3
-
219
-
-
0034793238
-
ATM as a target for novel radiosensitizers
-
Sarkaria J.N., and Eshleman J.S. ATM as a target for novel radiosensitizers. Semin Radiat Oncol 11 (2001) 316-327
-
(2001)
Semin Radiat Oncol
, vol.11
, pp. 316-327
-
-
Sarkaria, J.N.1
Eshleman, J.S.2
-
220
-
-
0030441833
-
Lisofylline as a modifier of radiation therapy
-
Wong J.S., Ara G., Keyes S.R., Herbst R., Coleman C.N., and Teicher B.A. Lisofylline as a modifier of radiation therapy. Oncol Res 8 (1996) 513-518
-
(1996)
Oncol Res
, vol.8
, pp. 513-518
-
-
Wong, J.S.1
Ara, G.2
Keyes, S.R.3
Herbst, R.4
Coleman, C.N.5
Teicher, B.A.6
-
221
-
-
29244484430
-
Radiation and new molecular agents. Part I: Targeting ATM-ATR checkpoints, DNA repair, and the proteasome
-
Choudhury A., Cuddihy A., and Bristow R.G. Radiation and new molecular agents. Part I: Targeting ATM-ATR checkpoints, DNA repair, and the proteasome. Semin Radiat Oncol 16 (2006) 51-58
-
(2006)
Semin Radiat Oncol
, vol.16
, pp. 51-58
-
-
Choudhury, A.1
Cuddihy, A.2
Bristow, R.G.3
-
222
-
-
29244492286
-
Radiation and new molecular agents. Part II: Targeting HDAC, HSP90, IGF-1R, PI3K, and Ras
-
Chinnaiyan P., Allen G.W., and Harari P.M. Radiation and new molecular agents. Part II: Targeting HDAC, HSP90, IGF-1R, PI3K, and Ras. Semin Radiat Oncol 16 (2006) 59-64
-
(2006)
Semin Radiat Oncol
, vol.16
, pp. 59-64
-
-
Chinnaiyan, P.1
Allen, G.W.2
Harari, P.M.3
-
223
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3 (2003) 11-22
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
225
-
-
22144492563
-
Molecular targets for altering radiosensitivity: lessons from Ras as a pre-clinical and clinical model
-
Cengel K.A., and McKenna W.G. Molecular targets for altering radiosensitivity: lessons from Ras as a pre-clinical and clinical model. Crit Rev Oncol Hematol 55 (2005) 103-116
-
(2005)
Crit Rev Oncol Hematol
, vol.55
, pp. 103-116
-
-
Cengel, K.A.1
McKenna, W.G.2
-
226
-
-
20444492764
-
Mechanisms of disease: radiosensitization by epidermal growth factor receptor inhibitors
-
Sartor C.I. Mechanisms of disease: radiosensitization by epidermal growth factor receptor inhibitors. Nat Clin Pract Oncol 1 (2004) 80-87
-
(2004)
Nat Clin Pract Oncol
, vol.1
, pp. 80-87
-
-
Sartor, C.I.1
-
227
-
-
11144223542
-
ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: schedule-dependent enhancement of antitumor activity
-
Williams K.J., Telfer B.A., Brave S., et al. ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: schedule-dependent enhancement of antitumor activity. Clin Cancer Res 10 (2004) 8587-8593
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8587-8593
-
-
Williams, K.J.1
Telfer, B.A.2
Brave, S.3
-
228
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner J.A., Harari P.M., Giralt J., et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354 (2006) 567-578
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
229
-
-
32144463481
-
Cetuximab and radiotherapy for head and neck cancer
-
Posner M.R., and Wirth L.J. Cetuximab and radiotherapy for head and neck cancer. N Engl J Med 354 (2006) 634-636
-
(2006)
N Engl J Med
, vol.354
, pp. 634-636
-
-
Posner, M.R.1
Wirth, L.J.2
-
230
-
-
29244448296
-
Radiation combined with EGFR signal inhibitors: head and neck cancer focus
-
Harari P.M., and Huang S. Radiation combined with EGFR signal inhibitors: head and neck cancer focus. Semin Radiat Oncol 16 (2006) 38-44
-
(2006)
Semin Radiat Oncol
, vol.16
, pp. 38-44
-
-
Harari, P.M.1
Huang, S.2
-
231
-
-
20944447527
-
A phase I clinical trial of thoracic radiotherapy and concurrent celecoxib for patients with unfavorable performance status inoperable/unresectable non-small cell lung cancer
-
Liao Z., Komaki R., Milas L., et al. A phase I clinical trial of thoracic radiotherapy and concurrent celecoxib for patients with unfavorable performance status inoperable/unresectable non-small cell lung cancer. Clin Cancer Res 11 (2005) 3342-3348
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3342-3348
-
-
Liao, Z.1
Komaki, R.2
Milas, L.3
-
232
-
-
24944579985
-
Inhibition of DNA repair as a mechanism of enhanced radioresponse of head and neck carcinoma cells by a selective cyclooxygenase-2 inhibitor, celecoxib
-
Raju U., Ariga H., Dittmann K., Nakata E., Ang K.K., and Milas L. Inhibition of DNA repair as a mechanism of enhanced radioresponse of head and neck carcinoma cells by a selective cyclooxygenase-2 inhibitor, celecoxib. Int J Radiat Oncol Biol Phys 63 (2005) 520-528
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.63
, pp. 520-528
-
-
Raju, U.1
Ariga, H.2
Dittmann, K.3
Nakata, E.4
Ang, K.K.5
Milas, L.6
-
233
-
-
33745976468
-
Current status of angiogenesis inhibitors combined with radiation therapy
-
Nieder C., Wiedenmann N., Andratschke N., and Molls M. Current status of angiogenesis inhibitors combined with radiation therapy. Cancer Treat Rev 32 (2006) 348-364
-
(2006)
Cancer Treat Rev
, vol.32
, pp. 348-364
-
-
Nieder, C.1
Wiedenmann, N.2
Andratschke, N.3
Molls, M.4
-
234
-
-
33845608378
-
Sulfoglycolipids as candidate antiangiogenic radiosensitizers
-
Miura M., Sakimoto I., Ohta K., Sugawara F., and Sakaguchi K. Sulfoglycolipids as candidate antiangiogenic radiosensitizers. Anti-Cancer Drugs 18 (2007) 1-5
-
(2007)
Anti-Cancer Drugs
, vol.18
, pp. 1-5
-
-
Miura, M.1
Sakimoto, I.2
Ohta, K.3
Sugawara, F.4
Sakaguchi, K.5
-
235
-
-
0041384191
-
Membrane targeted anticancer drugs: potent inducers of apoptosis and putative radiosensitizers
-
Jendrossek V., and Handrick R. Membrane targeted anticancer drugs: potent inducers of apoptosis and putative radiosensitizers. Curr Med Chem Anti-Cancer Agents 3 (2003) 343-353
-
(2003)
Curr Med Chem Anti-Cancer Agents
, vol.3
, pp. 343-353
-
-
Jendrossek, V.1
Handrick, R.2
-
236
-
-
0001298881
-
Sensitization of Escherichia coli to gamma-radiation by N-ethylmaleimide
-
Bridges B.A. Sensitization of Escherichia coli to gamma-radiation by N-ethylmaleimide. Nature 4748 (1960) 415
-
(1960)
Nature
, vol.4748
, pp. 415
-
-
Bridges, B.A.1
-
237
-
-
34347272087
-
Sensitization of organisms to radiation by sulfhydryl-binding agents
-
Bridges B.A. Sensitization of organisms to radiation by sulfhydryl-binding agents. Adv Radiat Biol 3 (1969) 123-176
-
(1969)
Adv Radiat Biol
, vol.3
, pp. 123-176
-
-
Bridges, B.A.1
-
238
-
-
0016812351
-
Studies of the mechanisms of radiosensitization of bacterial and mammalian cells by diamide
-
Watts M.E., Whillans D.W., and Adams G.E. Studies of the mechanisms of radiosensitization of bacterial and mammalian cells by diamide. Int J Radiat Biol 27 (1975) 259-270
-
(1975)
Int J Radiat Biol
, vol.27
, pp. 259-270
-
-
Watts, M.E.1
Whillans, D.W.2
Adams, G.E.3
-
239
-
-
0018578116
-
Mammalian cell studies with diamide
-
Harris J.W. Mammalian cell studies with diamide. Pharmacol Ther 7 (1979) 375-391
-
(1979)
Pharmacol Ther
, vol.7
, pp. 375-391
-
-
Harris, J.W.1
-
240
-
-
0001437470
-
Thiol reactivity towards drugs and radicals: some implications in the radiotherapy and chemotherapy of cancer
-
Chatgilialoglu C., and Asmus K.-D. (Eds), Plenum Press, New York
-
Wardman P. Thiol reactivity towards drugs and radicals: some implications in the radiotherapy and chemotherapy of cancer. In: Chatgilialoglu C., and Asmus K.-D. (Eds). Sulfur-centered reactive intermediates in chemistry and biology (1990), Plenum Press, New York 415-427
-
(1990)
Sulfur-centered reactive intermediates in chemistry and biology
, pp. 415-427
-
-
Wardman, P.1
-
241
-
-
0018666729
-
Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
-
Griffith O.W., and Meister A. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J Biol Chem 254 (1979) 7558-7560
-
(1979)
J Biol Chem
, vol.254
, pp. 7558-7560
-
-
Griffith, O.W.1
Meister, A.2
-
242
-
-
0020686664
-
Enhancement of misonidazole radiosensitization by an inhibitor of glutathione biosynthesis
-
Hodgkiss R.J., and Middleton R.W. Enhancement of misonidazole radiosensitization by an inhibitor of glutathione biosynthesis. Int J Radiat Biol 43 (1983) 179-183
-
(1983)
Int J Radiat Biol
, vol.43
, pp. 179-183
-
-
Hodgkiss, R.J.1
Middleton, R.W.2
-
243
-
-
0021184331
-
Glutathione depletion in tissues after administration of buthionine sulphoximine
-
Minchinton A.I., Rojas A., Smith K.A., et al. Glutathione depletion in tissues after administration of buthionine sulphoximine. Int J Radiat Oncol Biol Phys 10 (1984) 1261-1264
-
(1984)
Int J Radiat Oncol Biol Phys
, vol.10
, pp. 1261-1264
-
-
Minchinton, A.I.1
Rojas, A.2
Smith, K.A.3
-
244
-
-
0021741393
-
Enhancement of misonidazole radiosensitization by buthionine sulphoximine
-
Rojas A., Smith K.A., Soranson J.A., Minchinton A.I., Middleton R.W., and Denekamp J. Enhancement of misonidazole radiosensitization by buthionine sulphoximine. Radiother Oncol 2 (1984) 325-332
-
(1984)
Radiother Oncol
, vol.2
, pp. 325-332
-
-
Rojas, A.1
Smith, K.A.2
Soranson, J.A.3
Minchinton, A.I.4
Middleton, R.W.5
Denekamp, J.6
-
245
-
-
0023181928
-
SR-2508 plus buthionine sulfoximine or SR-2508 alone: effect on the radiation response and the glutathione content of a human tumor xenograft
-
Lespinasse F., Biscay P., Malaise E.P., and Guichard M. SR-2508 plus buthionine sulfoximine or SR-2508 alone: effect on the radiation response and the glutathione content of a human tumor xenograft. Radiat Res 110 (1987) 149-154
-
(1987)
Radiat Res
, vol.110
, pp. 149-154
-
-
Lespinasse, F.1
Biscay, P.2
Malaise, E.P.3
Guichard, M.4
-
246
-
-
0023018874
-
Radiosensitizing effect of misonidazole in combination with an inhibitor of glutathione synthesis in murine tumors
-
Ono K., Komuro C., Nishidai T., et al. Radiosensitizing effect of misonidazole in combination with an inhibitor of glutathione synthesis in murine tumors. Int J Radiat Oncol Biol Phys 12 (1986) 1661-1666
-
(1986)
Int J Radiat Oncol Biol Phys
, vol.12
, pp. 1661-1666
-
-
Ono, K.1
Komuro, C.2
Nishidai, T.3
-
247
-
-
0025923092
-
Spatial characterization of glutathione depletion in the KHT sarcoma using flow cytometry
-
Minchinton A.I., and Chaplin D.J. Spatial characterization of glutathione depletion in the KHT sarcoma using flow cytometry. Int J Radiat Biol 59 (1991) 1425-1433
-
(1991)
Int J Radiat Biol
, vol.59
, pp. 1425-1433
-
-
Minchinton, A.I.1
Chaplin, D.J.2
-
248
-
-
0034075992
-
Microregional heterogeneity of non-protein thiols in cervical carcinomas assessed by combined use of HPLC and fluorescence image analysis
-
Vukovic V., Nicklee T., and Hedley D.W. Microregional heterogeneity of non-protein thiols in cervical carcinomas assessed by combined use of HPLC and fluorescence image analysis. Clin Cancer Res 6 (2000) 1826-1832
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1826-1832
-
-
Vukovic, V.1
Nicklee, T.2
Hedley, D.W.3
-
249
-
-
0035400504
-
Differential effects of buthionine sulphoximine in hypoxic and non-hypoxic regions of human cervical carcinoma xenografts
-
Vukovic V., Nicklee T., and Hedley D.W. Differential effects of buthionine sulphoximine in hypoxic and non-hypoxic regions of human cervical carcinoma xenografts. Radiother Oncol 60 (2001) 69-73
-
(2001)
Radiother Oncol
, vol.60
, pp. 69-73
-
-
Vukovic, V.1
Nicklee, T.2
Hedley, D.W.3
-
250
-
-
0030658870
-
Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan
-
Bailey H.H., Ripple G., Tutsch K.D., et al. Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan. J Natl Cancer Inst 89 (1997) 1789-1796
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1789-1796
-
-
Bailey, H.H.1
Ripple, G.2
Tutsch, K.D.3
-
251
-
-
4243987802
-
L-S,R-buthionine sulfoximine: historical development and clinical issues
-
Bailey H.H. L-S,R-buthionine sulfoximine: historical development and clinical issues. Chem Biol Interact 111-112 (1998) 239-254
-
(1998)
Chem Biol Interact
, vol.111-112
, pp. 239-254
-
-
Bailey, H.H.1
-
252
-
-
33947409143
-
Structure-based identification of novel classes of human γ-glutamylcysteine synthetase inhibitors
-
Hamilton D., Wu J., and Batist G. Structure-based identification of novel classes of human γ-glutamylcysteine synthetase inhibitors. Mol Pharmacol 71 (2007) 1140-1147
-
(2007)
Mol Pharmacol
, vol.71
, pp. 1140-1147
-
-
Hamilton, D.1
Wu, J.2
Batist, G.3
-
253
-
-
0029739455
-
Cysteine concentrations in rodent tumors: unexpectedly high values may cause therapy resistance
-
Koch C.J., and Evans S.M. Cysteine concentrations in rodent tumors: unexpectedly high values may cause therapy resistance. Br J Cancer 67 (1996) 661-667
-
(1996)
Br J Cancer
, vol.67
, pp. 661-667
-
-
Koch, C.J.1
Evans, S.M.2
-
254
-
-
2642538300
-
Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage
-
Kinnaert E., Duez P., Morandini R., Dubois J., Van Houtte P., and Ghanem G. Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage. Pigment Cell Res 17 (2004) 275-280
-
(2004)
Pigment Cell Res
, vol.17
, pp. 275-280
-
-
Kinnaert, E.1
Duez, P.2
Morandini, R.3
Dubois, J.4
Van Houtte, P.5
Ghanem, G.6
-
255
-
-
0037384491
-
Radiation response of cells during altered protein thiol redox
-
Biaglow J.E., Ayene I.S., Koch C.J., et al. Radiation response of cells during altered protein thiol redox. Radiat Res 159 (2003) 484-494
-
(2003)
Radiat Res
, vol.159
, pp. 484-494
-
-
Biaglow, J.E.1
Ayene, I.S.2
Koch, C.J.3
-
256
-
-
0021024099
-
Pulse radiolytic study of the interaction of thiols and ascorbate with OH adducts of dGMP and dG: implications for DNA repair processes
-
O'Neill P. Pulse radiolytic study of the interaction of thiols and ascorbate with OH adducts of dGMP and dG: implications for DNA repair processes. Radiat Res 96 (1983) 198-210
-
(1983)
Radiat Res
, vol.96
, pp. 198-210
-
-
O'Neill, P.1
-
257
-
-
0023758360
-
Competitive dose-modification between ascorbate and misonidazole in human and hamster cells: effects of glutathione depletion
-
Hodgkiss R.J., and Stratford M.R.L. Competitive dose-modification between ascorbate and misonidazole in human and hamster cells: effects of glutathione depletion. Int J Radiat Biol 54 (1988) 601-610
-
(1988)
Int J Radiat Biol
, vol.54
, pp. 601-610
-
-
Hodgkiss, R.J.1
Stratford, M.R.L.2
-
258
-
-
0032944891
-
Clinical radiosensitization: why it does and does not work
-
Coleman C.N., and Mitchell J.B. Clinical radiosensitization: why it does and does not work. J Clin Oncol 17 (1999) 1-3
-
(1999)
J Clin Oncol
, vol.17
, pp. 1-3
-
-
Coleman, C.N.1
Mitchell, J.B.2
-
259
-
-
0016586659
-
Distribution of ascorbic acid, metabolites and analogues in man and animals
-
Hornig D. Distribution of ascorbic acid, metabolites and analogues in man and animals. Ann NY Acad Sci 258 (1975) 103-117
-
(1975)
Ann NY Acad Sci
, vol.258
, pp. 103-117
-
-
Hornig, D.1
-
260
-
-
0031878182
-
Evaluation of the 'radical sink' hypothesis from a chemical-kinetic viewpoint
-
Wardman P. Evaluation of the 'radical sink' hypothesis from a chemical-kinetic viewpoint. J Radioanal Nucl Chem 232 (1998) 23-27
-
(1998)
J Radioanal Nucl Chem
, vol.232
, pp. 23-27
-
-
Wardman, P.1
|