메뉴 건너뛰기




Volumn 24, Issue 4, 2006, Pages 444-456

New and emerging radiosensitizers and radioprotectors

Author keywords

Chemotherapy; Radiation; Radioprotection; Radiosensitization

Indexed keywords

AMIFOSTINE; BEVACIZUMAB; BORTEZOMIB; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; DOXORUBICIN; DRUG METABOLITE; ERLOTINIB; ERYTHROPOIETIN; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IRINOTECAN; NAVELBINE; OXALIPLATIN; PACLITAXEL; PROTEIN TYROSINE KINASE INHIBITOR; RADIOPROTECTIVE AGENT; RADIOSENSITIZING AGENT; TAXANE DERIVATIVE; TEMOZOLOMIDE; TIRAPAZAMINE; TRASTUZUMAB;

EID: 33745311283     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900600705706     Document Type: Review
Times cited : (43)

References (155)
  • 1
    • 2342592623 scopus 로고    scopus 로고
    • Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer
    • Bernier, J.; Domenge, C.; Ozsahin, M.; Matuszewska, K.; Lefebvre, J.L.; et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N. Engl. J. Med. 2004, 350, 1945-1952.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1945-1952
    • Bernier, J.1    Domenge, C.2    Ozsahin, M.3    Matuszewska, K.4    Lefebvre, J.L.5
  • 2
    • 2342517421 scopus 로고    scopus 로고
    • Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck
    • Cooper, J.S.; Pajak, T.F.; Forastiere, A.A.; Jacobs, J.; Campbell, B.H.; et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N. Engl. J. Med. 2004, 350, 1937-1944.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1937-1944
    • Cooper, J.S.1    Pajak, T.F.2    Forastiere, A.A.3    Jacobs, J.4    Campbell, B.H.5
  • 3
    • 0032543663 scopus 로고    scopus 로고
    • Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer
    • Brizel, D.M.; Albers, M.E.; Fisher, S.R.; Scher, R.L.; Richtsmeier, W.J.; et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N. Engl. J. Med. 1998, 338, 1798-1804.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1798-1804
    • Brizel, D.M.1    Albers, M.E.2    Fisher, S.R.3    Scher, R.L.4    Richtsmeier, W.J.5
  • 4
    • 0345714860 scopus 로고    scopus 로고
    • Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer
    • Forastiere, A.A.; Goepfert, H.; Maor, M.; Pajak, T.F.; Weber, R.; et al. Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N. Engl. J. Med. 2003, 349, 2091-2098.
    • (2003) N. Engl. J. Med. , vol.349 , pp. 2091-2098
    • Forastiere, A.A.1    Goepfert, H.2    Maor, M.3    Pajak, T.F.4    Weber, R.5
  • 5
    • 0037083482 scopus 로고    scopus 로고
    • Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix
    • Pearcey, R.; Brundage, M.; Drouin, P.; Jeffrey, J.; Johnston, D.; et al. Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix. J. Clin. Oncol. 2002, 20, 966-972.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 966-972
    • Pearcey, R.1    Brundage, M.2    Drouin, P.3    Jeffrey, J.4    Johnston, D.5
  • 6
    • 0033993937 scopus 로고    scopus 로고
    • Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix
    • Peters, W.A.; 3rd, Liu, P.Y.; Barrett, R.J.; 2nd, Stock, R.J.; Monk, B.J.; et al. Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J. Clin. Oncol. 2000, 18, 1606-1613.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1606-1613
    • Peters III, W.A.1    Liu, P.Y.2    Barrett II, R.J.3    Stock, R.J.4    Monk, B.J.5
  • 7
    • 0033561204 scopus 로고    scopus 로고
    • Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer
    • Morris, M.; Eifel, P.J.; Lu, J.; Grigsby, P.W.; Levenback, C.; et al. Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N. Engl. J. Med. 1999, 340, 1137-1143.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1137-1143
    • Morris, M.1    Eifel, P.J.2    Lu, J.3    Grigsby, P.W.4    Levenback, C.5
  • 8
    • 0033561259 scopus 로고    scopus 로고
    • Cisplatin radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma
    • Keys, H.M.; Bundy, B.N.; Stehman, F.B.; Muderspach, L.I.; Chafe, W.E.; et al. Cisplatin radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N. Engl. J. Med. 1999, 340, 1154-1161.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1154-1161
    • Keys, H.M.1    Bundy, B.N.2    Stehman, F.B.3    Muderspach, L.I.4    Chafe, W.E.5
  • 9
    • 0033561333 scopus 로고    scopus 로고
    • Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer
    • Rose, P.G.; Bundy, B.N.; Watkins, E.B.; Thigpen, J.T.; Deppe, G.; et al. Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N. Engl. J. Med. 1999, 340, 1144-1153.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1144-1153
    • Rose, P.G.1    Bundy, B.N.2    Watkins, E.B.3    Thigpen, J.T.4    Deppe, G.5
  • 10
    • 0032895783 scopus 로고    scopus 로고
    • Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: A Gynecologic Oncology Group and Southwest Oncology Group study
    • Whitney, C.W.; Sause, W.; Bundy, B.N.; Malfetano, J.H.; Hannigan, E.V.; et al. Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study. J. Clin. Oncol. 1999, 17, 1339-1348.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1339-1348
    • Whitney, C.W.1    Sause, W.2    Bundy, B.N.3    Malfetano, J.H.4    Hannigan, E.V.5
  • 11
    • 0033526355 scopus 로고    scopus 로고
    • Chemoradiotherapy of locally advanced esophageal cancer: Long-term follow-up of a prospective randomized trial (RTOG 85-01)
    • Radiation Therapy Oncology Group
    • Cooper, J.S.; Guo, M.D.; Herskovic, A.; Macdonald, J.S.; Martenson, J.A. Jr.; et al. Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group. Jama 1999, 281, 1623-1627.
    • (1999) Jama , vol.281 , pp. 1623-1627
    • Cooper, J.S.1    Guo, M.D.2    Herskovic, A.3    Macdonald, J.S.4    Martenson Jr., J.A.5
  • 12
    • 0035863382 scopus 로고    scopus 로고
    • Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma
    • Urba, S.G.; Orringer, M.B.; Turrisi, A.; Iannettoni, M.; Forastiere, A.; et al. Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma. J. Clin. Oncol. 2001, 19. 305-313.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 305-313
    • Urba, S.G.1    Orringer, M.B.2    Turrisi, A.3    Iannettoni, M.4    Forastiere, A.5
  • 13
    • 0035818048 scopus 로고    scopus 로고
    • Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction
    • Macdonald, J.S.; Smalley, S.R.; Benedetti, J.; Hundahl, S.A.; Estes, N.C.; et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N. Engl. J. Med. 2001, 345, 725-730.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 725-730
    • Macdonald, J.S.1    Smalley, S.R.2    Benedetti, J.3    Hundahl, S.A.4    Estes, N.C.5
  • 14
    • 0033993435 scopus 로고    scopus 로고
    • 3rd Final results of Phase III trial in regionally advanced unresectable non-small cell lung cancer: Radiation Therapy Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group
    • Sause, W.; Kolesar, P.; Taylor, S.I.; Johnson, D.; Livingston, R.; et al. 3rd Final results of Phase III trial in regionally advanced unresectable non-small cell lung cancer: Radiation Therapy Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group. Chest 2000, 117, 358-364.
    • (2000) Chest , vol.117 , pp. 358-364
    • Sause, W.1    Kolesar, P.2    Taylor, S.I.3    Johnson, D.4    Livingston, R.5
  • 15
    • 0029778934 scopus 로고    scopus 로고
    • Improved survival in stage III non-small-cell lung cancer: Seven-year follow-up of cancer and leukemia group B (CALGB) 8433 trial
    • Dillman, R.O.; Herndon, J.; Seagren, S.L.; Eaton, W. L. Jr.; Green, M.R. et al. Improved survival in stage III non-small-cell lung cancer: seven-year follow-up of cancer and leukemia group B (CALGB) 8433 trial. J. Natl. Cancer. Inst. 1996, 88, 1210-1215.
    • (1996) J. Natl. Cancer. Inst. , vol.88 , pp. 1210-1215
    • Dillman, R.O.1    Herndon, J.2    Seagren, S.L.3    Eaton Jr., W.L.4    Green, M.R.5
  • 17
    • 0021792174 scopus 로고
    • Prolongation of the disease-free interval in surgically treated rectal carcinoma
    • Gastrointestinal Tumor Study Group
    • Prolongation of the disease-free interval in surgically treated rectal carcinoma. Gastrointestinal Tumor Study Group. N. Engl. J. Med. 1985, 312, 1465-1472.
    • (1985) N. Engl. J. Med. , vol.312 , pp. 1465-1472
  • 18
    • 0000278788 scopus 로고    scopus 로고
    • Epidermoid anal cancer: Results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin
    • UKCCCR Anal Cancer Trial Working Party. UK Coordinating Committee on Cancer Research
    • Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Coordinating Committee on Cancer Research. Lancet 1996, 348, 1049-1054.
    • (1996) Lancet , vol.348 , pp. 1049-1054
  • 19
    • 0031004470 scopus 로고    scopus 로고
    • Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: Results of a Phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups
    • Bartelink, H.; Roelofsen, F.; Eschwege, F.; Rougier, P.; Bosset, J.F.; et al. Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a Phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. J. Clin. Oncol. 1997, 15, 2040-2049.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 2040-2049
    • Bartelink, H.1    Roelofsen, F.2    Eschwege, F.3    Rougier, P.4    Bosset, J.F.5
  • 20
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp, R.; Mason, W.P.; van den Bent, M.J.; Weller, M.; Fisher, B.; et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 2005, 352, 987-996.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3    Weller, M.4    Fisher, B.5
  • 22
    • 1342289781 scopus 로고    scopus 로고
    • Phase I trial using a time-to-event continual reassessment strategy for dose escalation of cisplatin combined with gemcitabine and radiation therapy in pancreatic cancer
    • Muler, J.H.; McGinn, C.J.; Normolle, D.; Lawrence, T.; Brown, D.; et al. Phase I trial using a time-to-event continual reassessment strategy for dose escalation of cisplatin combined with gemcitabine and radiation therapy in pancreatic cancer. J. Clin. Oncol. 2004, 22, 238-243.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 238-243
    • Muler, J.H.1    McGinn, C.J.2    Normolle, D.3    Lawrence, T.4    Brown, D.5
  • 23
    • 0023262033 scopus 로고
    • Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer
    • Gastrointestinal Tumor Study Group
    • Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Gastrointestinal Tumor Study Group. Cancer 1987, 59, 2006-2010.
    • (1987) Cancer , vol.59 , pp. 2006-2010
  • 24
    • 0141757451 scopus 로고    scopus 로고
    • Radiation and ceramide-induced apoptosis
    • Kolesnick, R.; Fuks, Z. Radiation and ceramide-induced apoptosis. Oncogene 2003, 22, 5897-5906.
    • (2003) Oncogene , vol.22 , pp. 5897-5906
    • Kolesnick, R.1    Fuks, Z.2
  • 25
    • 23044502688 scopus 로고    scopus 로고
    • Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy
    • Cao, Y.; Tsien, C.I.; Shen, Z.; Tatro, D.S.; Ten Haken, R.; et al. Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy. J. Clin. Oncol. 2005, 23, 4127-4136.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 4127-4136
    • Cao, Y.1    Tsien, C.I.2    Shen, Z.3    Tatro, D.S.4    Ten Haken, R.5
  • 26
    • 0037270737 scopus 로고    scopus 로고
    • The mechanism of action of radiosensitization of conventional chemotherapeutic agents
    • Lawrence, T.S.; Blackstock, A.W.; McGinn, C. The mechanism of action of radiosensitization of conventional chemotherapeutic agents. Semin Radiat Oncol. 2003, 13, 13-21.
    • (2003) Semin Radiat Oncol. , vol.13 , pp. 13-21
    • Lawrence, T.S.1    Blackstock, A.W.2    McGinn, C.3
  • 27
    • 0030272199 scopus 로고    scopus 로고
    • Tumor retention of 5-fluorouracil following irradiation observed using 19F nuclear magnetic resonance spectroscopy
    • Blackstock, A.W.; Kwock, L.; Branch, C.; Zeman, E.M.; Tepper, J.E. Tumor retention of 5-fluorouracil following irradiation observed using 19F nuclear magnetic resonance spectroscopy. Int. J. Radiat. Oncol. Biol. Phys. 1996, 36, 641-648.
    • (1996) Int. J. Radiat. Oncol. Biol. Phys. , vol.36 , pp. 641-648
    • Blackstock, A.W.1    Kwock, L.2    Branch, C.3    Zeman, E.M.4    Tepper, J.E.5
  • 28
    • 11144354392 scopus 로고    scopus 로고
    • Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
    • Willett, C.G.; Boucher, Y.; di Tomaso, E.; Duda, D.G.; Munn, L.L.; et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat. Med. 2004, 10, 145-147.
    • (2004) Nat. Med. , vol.10 , pp. 145-147
    • Willett, C.G.1    Boucher, Y.2    Di Tomaso, E.3    Duda, D.G.4    Munn, L.L.5
  • 29
    • 11144284657 scopus 로고    scopus 로고
    • Concomitant chemotherapy and radiation therapy certainly improves local control
    • Cooper, J.S.; Ang, K.K. Concomitant chemotherapy and radiation therapy certainly improves local control. Int. J. Radiat. Oncol. Biol. Phys. 2005, 61, 7-9.
    • (2005) Int. J. Radiat. Oncol. Biol. Phys. , vol.61 , pp. 7-9
    • Cooper, J.S.1    Ang, K.K.2
  • 30
    • 0041707983 scopus 로고    scopus 로고
    • Intensive concurrent chemoradiotherapy for head and neck cancer with 5-Fluorouracil- and hydroxyurea-based regimens: Reversing a pattern of failure
    • Argiris, A.; Haraf, D.J.; Kies, M.S.; Vokes, E.E. Intensive concurrent chemoradiotherapy for head and neck cancer with 5-Fluorouracil- and hydroxyurea-based regimens: reversing a pattern of failure. Oncologist 2003, 8, 350-360.
    • (2003) Oncologist , vol.8 , pp. 350-360
    • Argiris, A.1    Haraf, D.J.2    Kies, M.S.3    Vokes, E.E.4
  • 31
    • 0034034509 scopus 로고    scopus 로고
    • Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: A prospective randomized trial
    • Jeremic, B.; Shibamoto, Y.; Milicic, B.; Nikolic, N.; Dagovic, A.; et al. Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial. J. Clin. Oncol. 2000, 18, 1458-1464.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1458-1464
    • Jeremic, B.1    Shibamoto, Y.2    Milicic, B.3    Nikolic, N.4    Dagovic, A.5
  • 32
    • 10744228674 scopus 로고    scopus 로고
    • Concomitant gemcitabine (Gemzar) and extended nodes irradiation in the treatment of pancreatic and biliary carcinoma: A Phase I study
    • Morganti, A.G.; Trodella, L.; Valentini, V.; Macchia, G.; Alfieri, S.; et al. Concomitant gemcitabine (Gemzar) and extended nodes irradiation in the treatment of pancreatic and biliary carcinoma: a Phase I study. Onkologie 2003, 26325-329.
    • (2003) Onkologie , vol.26 , pp. 325-329
    • Morganti, A.G.1    Trodella, L.2    Valentini, V.3    Macchia, G.4    Alfieri, S.5
  • 33
    • 0034825882 scopus 로고    scopus 로고
    • Toxicity and efficacy of concurrent gemcitabine and radiotherapy for locally advanced pancreatic cancer
    • Crane, C.H.; Janjan, N.A.; Evans, D.B.; Wolff, R.A.; Ballo, M.T.; et al. Toxicity and efficacy of concurrent gemcitabine and radiotherapy for locally advanced pancreatic cancer. Int. J. Pancreatol. 2001, 29, 9-18.
    • (2001) Int. J. Pancreatol. , vol.29 , pp. 9-18
    • Crane, C.H.1    Janjan, N.A.2    Evans, D.B.3    Wolff, R.A.4    Ballo, M.T.5
  • 34
    • 0034889197 scopus 로고    scopus 로고
    • Drug synergism: Its detection and applications
    • Tallarida, R.J. Drug synergism: its detection and applications. J. Pharmacol. Exp. Ther. 2001, 298, 865-872.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 865-872
    • Tallarida, R.J.1
  • 35
    • 0018425119 scopus 로고
    • Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity
    • Steel, G.G.; Peckham, M.J. Exploitable mechanisms in combined radiotherapy-chemotherapy: the concept of additivity. Int. J. Radiat. Oncol. Biol. Phys. 1979, 5, 85-91.
    • (1979) Int. J. Radiat. Oncol. Biol. Phys. , vol.5 , pp. 85-91
    • Steel, G.G.1    Peckham, M.J.2
  • 37
    • 15544371477 scopus 로고    scopus 로고
    • Targeting cytotoxic conjugates of somatostatin, luteinizing hormone-releasing hormone and bombesin to cancers expressing their receptors: A "smarter" chemotherapy
    • Nagy, A.; Schally, A.V. Targeting cytotoxic conjugates of somatostatin, luteinizing hormone-releasing hormone and bombesin to cancers expressing their receptors: a "smarter" chemotherapy. Curr. Pharm. Des. 2005, 11, 1167-1180.
    • (2005) Curr. Pharm. Des. , vol.11 , pp. 1167-1180
    • Nagy, A.1    Schally, A.V.2
  • 38
    • 18044379750 scopus 로고    scopus 로고
    • Growth factor signalling networks in breast cancer and resistance to endocrine agents: New therapeutic strategies
    • Nicholson, R.I.; Hutcheson, I.R.; Britton, D.; Knowlden, J.M.; Jones, H.E.; et al. Growth factor signalling networks in breast cancer and resistance to endocrine agents: new therapeutic strategies. J. Steroid. Biochem. Mol. Biol. 2005, 93, 257-262.
    • (2005) J. Steroid. Biochem. Mol. Biol. , vol.93 , pp. 257-262
    • Nicholson, R.I.1    Hutcheson, I.R.2    Britton, D.3    Knowlden, J.M.4    Jones, H.E.5
  • 39
    • 16344364326 scopus 로고    scopus 로고
    • Expression genomics and drug development: Towards predictive pharmacology
    • Liu, E.T. Expression genomics and drug development: towards predictive pharmacology. Brief Funct. Genomic Proteomic. 2005, 3, 303-321.
    • (2005) Brief Funct. Genomic Proteomic. , vol.3 , pp. 303-321
    • Liu, E.T.1
  • 40
    • 84984929093 scopus 로고    scopus 로고
    • Deep-sea creatures yield treasure trove of cancer drugs
    • O'Hanlon, L.H. Deep-sea creatures yield treasure trove of cancer drugs. Nat. Med. 2005, 11, 698.
    • (2005) Nat. Med. , vol.11 , pp. 698
    • O'Hanlon, L.H.1
  • 41
    • 0038387494 scopus 로고    scopus 로고
    • 5-fluorouracil: Mechanisms of action and clinical strategies
    • Longley, D.B.; Harkin, D.P.; Johnston, P.G. 5-fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer. 2003, 3, 330-338.
    • (2003) Nat. Rev. Cancer. , vol.3 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 42
    • 0031796275 scopus 로고    scopus 로고
    • 5-fluorouracil: A pharmacological paradigm in the use of cytotoxics
    • Thomas, D.M.; Zalcberg, J.R. 5-fluorouracil: a pharmacological paradigm in the use of cytotoxics. Clin. Exp. Pharmacol. Physiol. 1998, 25, 887-895.
    • (1998) Clin. Exp. Pharmacol. Physiol. , vol.25 , pp. 887-895
    • Thomas, D.M.1    Zalcberg, J.R.2
  • 43
    • 0036499053 scopus 로고    scopus 로고
    • Radiation dose escalation in combined-modality therapy for esophageal cancer
    • Willett, C.G. Radiation dose escalation in combined-modality therapy for esophageal cancer. J. Clin. Oncol. 2002, 20, 1151-1153.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 1151-1153
    • Willett, C.G.1
  • 44
    • 0036096970 scopus 로고    scopus 로고
    • Results of radiation therapy in gastric cancer
    • Willett, C.G. Results of radiation therapy in gastric cancer. Semin. Radiat. Oncol. 2002, 12, 170-175.
    • (2002) Semin. Radiat. Oncol. , vol.12 , pp. 170-175
    • Willett, C.G.1
  • 45
    • 4544269347 scopus 로고    scopus 로고
    • The evolution of adjuvant and neoadjuvant chemotherapy and radiation for advanced pancreatic cancer: From 5-fluorouracil to GTX
    • Fogelman, D.R.; Chen, J.; Chabot, J.A.; Allendorf, J.D.; Schrope, B.A.; et al. The evolution of adjuvant and neoadjuvant chemotherapy and radiation for advanced pancreatic cancer: from 5-fluorouracil to GTX. Surg. Oncol. Clin. N. Am. 2004, 13, 711-735.
    • (2004) Surg. Oncol. Clin. N. Am. , vol.13 , pp. 711-735
    • Fogelman, D.R.1    Chen, J.2    Chabot, J.A.3    Allendorf, J.D.4    Schrope, B.A.5
  • 46
    • 13844292690 scopus 로고    scopus 로고
    • Combined modality treatment for rectal cancer
    • Zhu, A.X.; Willett, C.G. Combined modality treatment for rectal cancer. Semin. Oncol. 2005, 32, 103-112.
    • (2005) Semin. Oncol. , vol.32 , pp. 103-112
    • Zhu, A.X.1    Willett, C.G.2
  • 47
    • 0033818445 scopus 로고    scopus 로고
    • Chemoradiation for carcinoma of the cervix: Advances and opportunities
    • Eifel, P.J. Chemoradiation for carcinoma of the cervix: advances and opportunities. Radiat. Res. 2000, 154, 229-236.
    • (2000) Radiat. Res. , vol.154 , pp. 229-236
    • Eifel, P.J.1
  • 48
    • 0023628351 scopus 로고
    • The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes
    • Eastman, A. The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes. Pharmacol. Ther. 1987, 34, 155-166.
    • (1987) Pharmacol. Ther. , vol.34 , pp. 155-166
    • Eastman, A.1
  • 49
    • 9244240966 scopus 로고    scopus 로고
    • A meta-analysis of the timing of chest irradiation in the combined modality treatment of limited-stage small cell lung cancer
    • Huncharek, M.; McGarry, R. A meta-analysis of the timing of chest irradiation in the combined modality treatment of limited-stage small cell lung cancer. Oncologist 2004, 9, 665-672.
    • (2004) Oncologist , vol.9 , pp. 665-672
    • Huncharek, M.1    McGarry, R.2
  • 50
    • 12344266516 scopus 로고    scopus 로고
    • Organ preservation by combined modality treatment in bladder cancer: The European perspective
    • Rodel, C.; Weiss, C.; Sauer, R. Organ preservation by combined modality treatment in bladder cancer: the European perspective. Semin. Radiat. Oncol. 2005, 15, 28-35.
    • (2005) Semin. Radiat. Oncol. , vol.15 , pp. 28-35
    • Rodel, C.1    Weiss, C.2    Sauer, R.3
  • 51
    • 0345074111 scopus 로고    scopus 로고
    • Docetaxel, cisplatin, 5-fluorouracil (TPF)-based induction chemotherapy for head and neck cancer and the case for sequential, combined-modality treatment
    • Haddad, R.; Tishler, R.B.; Norris, C.M.; Mahadevan, A.; Busse, P.; et al. Docetaxel, cisplatin, 5-fluorouracil (TPF)-based induction chemotherapy for head and neck cancer and the case for sequential, combined-modality treatment. Oncologist 2003, 8, 35-44.
    • (2003) Oncologist , vol.8 , pp. 35-44
    • Haddad, R.1    Tishler, R.B.2    Norris, C.M.3    Mahadevan, A.4    Busse, P.5
  • 52
    • 10044289589 scopus 로고    scopus 로고
    • Chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck
    • Fanucchi, M.; Khuri, F.R. Chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck. Semin. Oncol. 2004, 31, 809-815.
    • (2004) Semin. Oncol. , vol.31 , pp. 809-815
    • Fanucchi, M.1    Khuri, F.R.2
  • 53
    • 2942648695 scopus 로고    scopus 로고
    • Four decades of continuing innovation with fluorouracil: Current and future approaches to fluorouracil chemoradiation therapy
    • Rich, T.A.; Shepard, R.C.; Mosley, S.T. Four decades of continuing innovation with fluorouracil: current and future approaches to fluorouracil chemoradiation therapy. J. Clin. Oncol. 2004, 22, 2214-2232.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 2214-2232
    • Rich, T.A.1    Shepard, R.C.2    Mosley, S.T.3
  • 54
    • 0035292514 scopus 로고    scopus 로고
    • Cisplatin and irinotecan in upper gastrointestinal malignancies
    • Huntingt
    • O'Reilly, E.M.; Ilson, D.H. Cisplatin and irinotecan in upper gastrointestinal malignancies. Oncology (Huntingt) 2001, 15, 42-45.
    • (2001) Oncology , vol.15 , pp. 42-45
    • O'Reilly, E.M.1    Ilson, D.H.2
  • 55
    • 0000460127 scopus 로고    scopus 로고
    • Oxaliplatin, tetraplatin, cisplatin, and carboplatin: Spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel
    • Rixe, O.; Ortuzar, W.; Alvarez, M.; Parker, R.; Reed, E.; et al. Oxaliplatin, tetraplatin, cisplatin, and carboplatin: spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel. Biochem. Pharmacol. 1996, 52, 1855-1865.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1855-1865
    • Rixe, O.1    Ortuzar, W.2    Alvarez, M.3    Parker, R.4    Reed, E.5
  • 56
    • 0028828382 scopus 로고
    • Cytotoxicity, cellular accumulation and DNA binding of oxaliplatin isomers
    • Pendyala, L.; Kidani, Y.; Perez, R.; Wilkes, J.; Bernacki, R.J.; et al. Cytotoxicity, cellular accumulation and DNA binding of oxaliplatin isomers. Cancer Lett. 1995, 97, 177-184.
    • (1995) Cancer Lett. , vol.97 , pp. 177-184
    • Pendyala, L.1    Kidani, Y.2    Perez, R.3    Wilkes, J.4    Bernacki, R.J.5
  • 57
    • 0028304413 scopus 로고
    • Enhanced replicative bypass of platinum-DNA adducts in cisplatin-resistant human ovarian carcinoma cell lines
    • Mamenta, E.L.; Poma, E.E.; Kaufmann, W.K.; Delmastro, D.A.; Grady, H.L.; et al. Enhanced replicative bypass of platinum-DNA adducts in cisplatin-resistant human ovarian carcinoma cell lines. Cancer Res. 1994, 54, 3500-3505.
    • (1994) Cancer Res. , vol.54 , pp. 3500-3505
    • Mamenta, E.L.1    Poma, E.E.2    Kaufmann, W.K.3    Delmastro, D.A.4    Grady, H.L.5
  • 58
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont, A.; Figer, A.; Seymour, M.; Homerin, M.; Hmissi, A.; et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J. Clin. Oncol. 2000, 18, 2938-2947.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 2938-2947
    • De Gramont, A.1    Figer, A.2    Seymour, M.3    Homerin, M.4    Hmissi, A.5
  • 59
    • 0035340318 scopus 로고    scopus 로고
    • Addition of oxaliplatin to continuous fluorouracil, I-folinic acid, and concomitant radiotherapy in rectal cancer: The Lyon R 97-03 Phase I trial
    • Freyer, G.; Bossard, N.; Romestaing, P.; Mornex, F.; Chapet, O.; et al. Addition of oxaliplatin to continuous fluorouracil, I-folinic acid, and concomitant radiotherapy in rectal cancer: the Lyon R 97-03 Phase I trial. J. Clin. Oncol. 2001, 19, 2433-2438.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 2433-2438
    • Freyer, G.1    Bossard, N.2    Romestaing, P.3    Mornex, F.4    Chapet, O.5
  • 60
    • 25444503968 scopus 로고    scopus 로고
    • A Phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer
    • Aschele, C.; Friso, M.L.; Pucciarelli, S.; Lonardi, S.; Sartor, L.; et al. A Phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer. Ann. Oncol. 2005, 16, 1140-1146.
    • (2005) Ann. Oncol. , vol.16 , pp. 1140-1146
    • Aschele, C.1    Friso, M.L.2    Pucciarelli, S.3    Lonardi, S.4    Sartor, L.5
  • 61
    • 0036803131 scopus 로고    scopus 로고
    • Radiochemotherapy with short daily infusion of low-dose oxaliplatin, leucovorin, and 5-FU in T3-T4 unresectable rectal cancer: A Phase II IATTGI study
    • Carraro, S.; Roca, E.L.; Cartelli, C.; Rafailovici, L.; Castillo Odena, S.; et al. Radiochemotherapy with short daily infusion of low-dose oxaliplatin, leucovorin, and 5-FU in T3-T4 unresectable rectal cancer: a Phase II IATTGI study. Int. J. Radiat. Oncol. Biol. Phys. 2002, 54, 397-402.
    • (2002) Int. J. Radiat. Oncol. Biol. Phys. , vol.54 , pp. 397-402
    • Carraro, S.1    Roca, E.L.2    Cartelli, C.3    Rafailovici, L.4    Castillo Odena, S.5
  • 62
    • 11344265484 scopus 로고    scopus 로고
    • A Phase I/II study of preoperative oxaliplatin (O), 5-fluorouracil (5-FU), and external beam radiation therapy (XRT) in locally advanced rectal cancer: CALGB 89901
    • Ryan, D.N.; D. Hollis, D.R.; Miedema, B.W.; Wadler, S.; Tepper, J.E.; et al. A Phase I/II study of preoperative oxaliplatin (O), 5-fluorouracil (5-FU), and external beam radiation therapy (XRT) in locally advanced rectal cancer: CALGB 89901. In: Proc ASCO 2004.
    • Proc ASCO 2004
    • Ryan, D.N.1    D. Hollis, D.R.2    Miedema, B.W.3    Wadler, S.4    Tepper, J.E.5
  • 63
    • 0043177758 scopus 로고    scopus 로고
    • A Phase I Study of Preoperative Radiation Therapy (RT) with Concurrent Protracted Continous Infusion 5-FU and Dose Escalating Oxaliplatin Followed by Surgery, Adjuvant 5-FU, and Leucovorin for Locally Advanced (T3/4) Rectal Adenocarcinoma
    • Rosenthal, D.I.; Catalano, P.; Haller, D.G.; Landry, J.C.; Sigurdson, E.R.; et al. A Phase I Study of Preoperative Radiation Therapy (RT) with Concurrent Protracted Continous Infusion 5-FU and Dose Escalating Oxaliplatin Followed by Surgery, Adjuvant 5-FU, and Leucovorin for Locally Advanced (T3/4) Rectal Adenocarcinoma [abstract]. In: Proc ASCO 2003.
    • Proc ASCO 2003
    • Rosenthal, D.I.1    Catalano, P.2    Haller, D.G.3    Landry, J.C.4    Sigurdson, E.R.5
  • 64
    • 0028839329 scopus 로고
    • Radiosensitization of human tumor cells by gemcitabine in vitro
    • Shewach, D.S.; Lawrence, T.S. Radiosensitization of human tumor cells by gemcitabine in vitro. Semin. Oncol. 1995, 22, 68-71.
    • (1995) Semin. Oncol. , vol.22 , pp. 68-71
    • Shewach, D.S.1    Lawrence, T.S.2
  • 65
    • 0030922494 scopus 로고    scopus 로고
    • Delayed radiosensitization of human colon carcinoma cells after a brief exposure to 2′,2′-difluoro-2′-deoxycytidine (Gemcitabine)
    • Lawrence, T.S.; Chang, E.Y.; Hahn, T.M.; Shewach, D.S. Delayed radiosensitization of human colon carcinoma cells after a brief exposure to 2′,2′-difluoro-2′-deoxycytidine (Gemcitabine). Clin. Cancer Res. 1997, 3, 777-782.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 777-782
    • Lawrence, T.S.1    Chang, E.Y.2    Hahn, T.M.3    Shewach, D.S.4
  • 66
    • 0031804603 scopus 로고    scopus 로고
    • Radiosensitizing potential of gemcitabine (2′,2′-difluoro- 2′-deoxycytidine) within the cell cycle in vitro
    • Latz, D.; Fleckenstein, K.; Eble, M.; Blatter, J.; Wannenmacher, M.; et al. Radiosensitizing potential of gemcitabine (2′,2′-difluoro- 2′-deoxycytidine) within the cell cycle in vitro. Int. J. Radiat. Oncol. Biol. Phys. 1998, 41, 875-882.
    • (1998) Int. J. Radiat. Oncol. Biol. Phys. , vol.41 , pp. 875-882
    • Latz, D.1    Fleckenstein, K.2    Eble, M.3    Blatter, J.4    Wannenmacher, M.5
  • 68
    • 0142219871 scopus 로고    scopus 로고
    • Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells
    • Robinson, B.W.; Im, M.M.; Ljungman, M.; Praz, F.; Shewach, D.S. Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells. Cancer Res. 2003, 63, 6935-6941.
    • (2003) Cancer Res. , vol.63 , pp. 6935-6941
    • Robinson, B.W.1    Im, M.M.2    Ljungman, M.3    Praz, F.4    Shewach, D.S.5
  • 69
    • 0035253713 scopus 로고    scopus 로고
    • Radiation concurrent with gemcitabine for locally advanced head and neck cancer: A Phase I trial and intracellular drug incorporation study
    • Eisbruch, A.; Shewach, D.S.; Bradford, C.R.; Littles, J.F.; Teknos, T.N.; et al. Radiation concurrent with gemcitabine for locally advanced head and neck cancer: a Phase I trial and intracellular drug incorporation study. J. Clin. Oncol. 2001, 19, 792-799.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 792-799
    • Eisbruch, A.1    Shewach, D.S.2    Bradford, C.R.3    Littles, J.F.4    Teknos, T.N.5
  • 70
    • 0033022613 scopus 로고    scopus 로고
    • Phase I trial of twice-weekly gemcitabine and concurrent radiation in patients with advanced pancreatic cancer
    • Blackstock, A.W.; Bernard, S.A.; Richards, F.; Eagle, K.S.; Case, L.D.; et al. Phase I trial of twice-weekly gemcitabine and concurrent radiation in patients with advanced pancreatic cancer. J. Clin. Oncol. 1999, 17, 2208-2212.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2208-2212
    • Blackstock, A.W.1    Bernard, S.A.2    Richards, F.3    Eagle, K.S.4    Case, L.D.5
  • 71
    • 0035786873 scopus 로고    scopus 로고
    • Phase I study of concomitant gemcitabine and IMRT for patients with unresectable adenocarcinoma of the pancreatic head
    • Crane, C.H.; Antolak, J.A.; Rosen, II, Forster, K.M.; Evans, D.B.; Janjan, N.A.; et al. Phase I study of concomitant gemcitabine and IMRT for patients with unresectable adenocarcinoma of the pancreatic head. Int. J. Gastrointest Cancer 2001, 30, 123-132.
    • (2001) Int. J. Gastrointest Cancer , vol.30 , pp. 123-132
    • Crane, C.H.1    Antolak, J.A.2    Rosen, I.I.3    Forster, K.M.4    Evans, D.B.5    Janjan, N.A.6
  • 73
    • 0035890443 scopus 로고    scopus 로고
    • Phase I trial of radiation dose escalation with concurrent weekly full-dose gemcitabine in patients with advanced pancreatic cancer
    • McGinn, C.J.; Zalupski, M.M.; Shureiqi, I.; Robertson, J.M.; Eckhauser, F.E.; et al. Phase I trial of radiation dose escalation with concurrent weekly full-dose gemcitabine in patients with advanced pancreatic cancer. J. Clin. Oncol. 2001, 19, 4202-4208.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 4202-4208
    • McGinn, C.J.1    Zalupski, M.M.2    Shureiqi, I.3    Robertson, J.M.4    Eckhauser, F.E.5
  • 74
    • 4344633285 scopus 로고    scopus 로고
    • Combined-modality therapy with gemcitabine and radiotherapy as a bladder preservation strategy: Results of a Phase I trial
    • Kent, E.; Sandler, H.; Montie, J.; Lee, C.; Herman, J.; et al. Combined-modality therapy with gemcitabine and radiotherapy as a bladder preservation strategy: results of a Phase I trial. J. Clin. Oncol. 2004, 22, 2540-2545.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 2540-2545
    • Kent, E.1    Sandler, H.2    Montie, J.3    Lee, C.4    Herman, J.5
  • 75
    • 2642519543 scopus 로고    scopus 로고
    • A Phase I dose escalation trial of gemcitabine with radiotherapy for breast cancer in the treatment of unresectable chest wall recurrences
    • Suh, W.W.; Schott, A.F.; Hayman, J.A.; Schipper, M. J.; Shewach, D.S.; et al. A Phase I dose escalation trial of gemcitabine with radiotherapy for breast cancer in the treatment of unresectable chest wall recurrences. Breast. J. 2004, 10, 204-210.
    • (2004) Breast. J. , vol.10 , pp. 204-210
    • Suh, W.W.1    Schott, A.F.2    Hayman, J.A.3    Schipper, M.J.4    Shewach, D.S.5
  • 76
    • 0037108701 scopus 로고    scopus 로고
    • Randomized Phase II study of cisplatin with gemcitabine or paclitaxel or vinorelbine as induction chemotherapy followed by concomitant chemoradiotherapy for stage INB non-small-cell lung cancer: Cancer and leukemia group B study 9431
    • Vokes, E.E.; Herndon, J.E.; 2nd, Crawford, J.; Leopold, K.A.; Perry, M.C.; et al. Randomized Phase II study of cisplatin with gemcitabine or paclitaxel or vinorelbine as induction chemotherapy followed by concomitant chemoradiotherapy for stage INB non-small-cell lung cancer: cancer and leukemia group B study 9431. J. Clin. Oncol. 2002, 20, 4191-4198.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 4191-4198
    • Vokes, E.E.1    Herndon II, J.E.2    Crawford, J.3    Leopold, K.A.4    Perry, M.C.5
  • 77
    • 0036159856 scopus 로고    scopus 로고
    • Radiation enhancement by the combined use of topoisomerase I inhibitors, RFS-2000 or CPT-11, and topoisomerase II inhibitor etoposide in human lung cancer cells
    • Kim, J.S.; Amorino, G.P.; Pyo, H.; Cao, Q.; Choy, H. Radiation enhancement by the combined use of topoisomerase I inhibitors, RFS-2000 or CPT-11, and topoisomerase II inhibitor etoposide in human lung cancer cells. Radiother. Oncol. 2002, 62, 61-67.
    • (2002) Radiother. Oncol. , vol.62 , pp. 61-67
    • Kim, J.S.1    Amorino, G.P.2    Pyo, H.3    Cao, Q.4    Choy, H.5
  • 78
    • 0004723937 scopus 로고    scopus 로고
    • A Phase I trial of outpatient weekly irinotecan/carboplatin and concurrent radiation for stage III unresectable non small-cell lung cancer: A Vanderbilt-Ingram Cancer Center Affiliate Network Trial
    • Chakravarthy, A.; Choy, H. A Phase I trial of outpatient weekly irinotecan/carboplatin and concurrent radiation for stage III unresectable non small-cell lung cancer: a Vanderbilt-Ingram Cancer Center Affiliate Network Trial. Clin. Lung Cancer 2000, 1, 310-311.
    • (2000) Clin. Lung Cancer , vol.1 , pp. 310-311
    • Chakravarthy, A.1    Choy, H.2
  • 79
    • 18544388957 scopus 로고    scopus 로고
    • Dose-escalation study of weekly irinotecan and daily carboplatin with concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer
    • Yamada, M.; Kudoh, S.; Fukuda, H.; Nakagawa, K.; Yamamoto, N.; et al. Dose-escalation study of weekly irinotecan and daily carboplatin with concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer. Br. J. Cancer 2002, 87, 258-263.
    • (2002) Br. J. Cancer , vol.87 , pp. 258-263
    • Yamada, M.1    Kudoh, S.2    Fukuda, H.3    Nakagawa, K.4    Yamamoto, N.5
  • 80
    • 4043057156 scopus 로고    scopus 로고
    • Phase I trial of combined-modality therapy for localized esophageal cancer: Escalating doses of continuous-infusion paclitaxel with cisplatin and concurrent radiation therapy
    • Brenner, B.; Ilson, D.H.; Minsky, B.D.; Bains, M.S.; Yong, W.; et al. Phase I trial of combined-modality therapy for localized esophageal cancer: escalating doses of continuous-infusion paclitaxel with cisplatin and concurrent radiation therapy. J. Clin. Oncol. 2004, 22, 45-52.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 45-52
    • Brenner, B.1    Ilson, D.H.2    Minsky, B.D.3    Bains, M.S.4    Yong, W.5
  • 81
    • 0347298702 scopus 로고    scopus 로고
    • Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer
    • Mehta, V.K.; Cho, C.; Ford, J.M.; Jambalos, C.; Poen, J.; et al. Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 2003, 55, 132-137.
    • (2003) Int. J. Radiat. Oncol. Biol. Phys. , vol.55 , pp. 132-137
    • Mehta, V.K.1    Cho, C.2    Ford, J.M.3    Jambalos, C.4    Poen, J.5
  • 82
    • 0030965077 scopus 로고    scopus 로고
    • Potentiation of murine MCa-4 carcinoma radioresponse by 9-amino-20(S)-camptothecin
    • Kirichenko, A.V.; Rich, T.A.; Newman, R.A.; Travis, E.L. Potentiation of murine MCa-4 carcinoma radioresponse by 9-amino-20(S)-camptothecin. Cancer Res. 1997, 57, 1929-1933.
    • (1997) Cancer Res. , vol.57 , pp. 1929-1933
    • Kirichenko, A.V.1    Rich, T.A.2    Newman, R.A.3    Travis, E.L.4
  • 83
    • 0028133013 scopus 로고
    • NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA
    • Denny, B.J.; Wheelhouse, R.T.; Stevens, M.F.; Tsang, L.L.; Slack, J.A. NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA. Biochemistry 1994, 33, 9045-9051.
    • (1994) Biochemistry , vol.33 , pp. 9045-9051
    • Denny, B.J.1    Wheelhouse, R.T.2    Stevens, M.F.3    Tsang, L.L.4    Slack, J.A.5
  • 84
    • 0034883452 scopus 로고    scopus 로고
    • Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: Studies with different O(6)-alkylating agents and retroviral backbones
    • Jansen, M.; Bardenheuer, W.; Sorg, U.R.; Seeber, S.; Flasshove, M.; et al. Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones. Eur. J. Haematol 2001, 67, 2-13.
    • (2001) Eur. J. Haematol. , vol.67 , pp. 2-13
    • Jansen, M.1    Bardenheuer, W.2    Sorg, U.R.3    Seeber, S.4    Flasshove, M.5
  • 85
    • 17444402489 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in the treatment of high grade gliomas
    • Lonardi, S.; Tosoni, A.; Brandes, A.A. Adjuvant chemotherapy in the treatment of high grade gliomas. Cancer Treat. Rev. 2005, 31, 79-89.
    • (2005) Cancer Treat. Rev. , vol.31 , pp. 79-89
    • Lonardi, S.1    Tosoni, A.2    Brandes, A.A.3
  • 86
    • 0035863293 scopus 로고    scopus 로고
    • Randomized trial of procarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma: A Medical Research Council trial
    • Randomized trial of procarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma: a Medical Research Council trial. J. Clin. Oncol. 2001, 19, 509-518.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 509-518
  • 88
    • 0033952360 scopus 로고    scopus 로고
    • Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy
    • Koukourakis, M.I.; Giatromanolaki, A.; Fountzilas, G.; Sivridis, E.; Gatter, K.C.; et al. Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy. Clin. Cancer Res. 2000, 6, 381-389.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 381-389
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Fountzilas, G.3    Sivridis, E.4    Gatter, K.C.5
  • 89
    • 0036787579 scopus 로고    scopus 로고
    • Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer
    • Dunst, J.; Reese, T.; Sutter, T.; Zuhlke, H.; Hinke, A.; et al. Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer. J. Clin. Oncol. 2002, 20, 3983-3991.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3983-3991
    • Dunst, J.1    Reese, T.2    Sutter, T.3    Zuhlke, H.4    Hinke, A.5
  • 90
    • 4143143285 scopus 로고    scopus 로고
    • Substitution of oral fluoropyrimidines for infusional fluorouracil with radiotherapy: How much data do we need?
    • Crane, C.H.; Sargent, D.J. Substitution of oral fluoropyrimidines for infusional fluorouracil with radiotherapy: how much data do we need? J. Clin. Oncol. 2004, 22, 2978-2981.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 2978-2981
    • Crane, C.H.1    Sargent, D.J.2
  • 91
    • 24944465683 scopus 로고    scopus 로고
    • Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer
    • Kim, J.C.; Kim, T.W.; Kim, J.H.; Yu, C.S.; Kim, H.C.; et al. Preoperative concurrent radiotherapy with capecitabine before total mesorectal excision in locally advanced rectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 2005.
    • (2005) Int. J. Radiat. Oncol. Biol. Phys.
    • Kim, J.C.1    Kim, T.W.2    Kim, J.H.3    Yu, C.S.4    Kim, H.C.5
  • 92
    • 20144375332 scopus 로고    scopus 로고
    • Phase I trial of capecitabine and weekly irinotecan in combination with radiotherapy for neoadjuvant therapy of rectal cancer
    • Hofheinz, R.D.; von Gerstenberg-Helldorf, B.; Wenz, F.; Gnad, U.; Kraus-Tiefenbacher, U.; et al. Phase I trial of capecitabine and weekly irinotecan in combination with radiotherapy for neoadjuvant therapy of rectal cancer. J. Clin. Oncol. 2005, 23, 1350-1357.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 1350-1357
    • Hofheinz, R.D.1    Von Gerstenberg-Helldorf, B.2    Wenz, F.3    Gnad, U.4    Kraus-Tiefenbacher, U.5
  • 93
    • 0142041932 scopus 로고    scopus 로고
    • Radiotherapy and oral capecitabine in the preoperative treatment of patients with rectal cancer: Rationale, preliminary results and perspectives
    • Corvo, R.; Pastrone, I.; Scolaro, T.; Marcenaro, M.; Berretta, L.; et al. Radiotherapy and oral capecitabine in the preoperative treatment of patients with rectal cancer: rationale, preliminary results and perspectives. Tumori 2003, 89, 361-367.
    • (2003) Tumori , vol.89 , pp. 361-367
    • Corvo, R.1    Pastrone, I.2    Scolaro, T.3    Marcenaro, M.4    Berretta, L.5
  • 94
    • 4444377696 scopus 로고    scopus 로고
    • Capecitabine (X) vs bolus 5-FU/leucovorin (LV) as adjuvant therapy for colon cancer (the X-ACT study): Efficacy results of a Phase III trial
    • Cassidy, J.S.; W. McKendrick, J.; Kröning, H.; Nowacki, M.P.; Seitz, J.F.; et al. Capecitabine (X) vs bolus 5-FU/leucovorin (LV) as adjuvant therapy for colon cancer (the X-ACT study): efficacy results of a Phase III trial. In: Proc ASCO 2004.
    • Proc ASCO 2004
    • Cassidy, J.S.1    W. McKendrick, J.2    Kröning, H.3    Nowacki, M.P.4    Seitz, J.F.5
  • 95
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown, J.M.; Wilson, W.R. Exploiting tumour hypoxia in cancer treatment. Nat. Rev. Cancer 2004, 4, 437-447.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 97
    • 0035863303 scopus 로고    scopus 로고
    • Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer
    • Rischin, D.; Peters, L.; Hicks, R.; Hughes, P.; Fisher, R.; et al. Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer. J. Clin. Oncol. 2001, 19, 535-542.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 535-542
    • Rischin, D.1    Peters, L.2    Hicks, R.3    Hughes, P.4    Fisher, R.5
  • 98
    • 16644377045 scopus 로고    scopus 로고
    • Tirapazamine, Cisplatin, and Radiation versus Fluorouracil, Cisplatin, and Radiation in patients with locally advanced head and neck cancer: A randomized Phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02)
    • Rischin, D.; Peters, L.; Fisher, R.; Macann, A.; Denham, J.; et al. Tirapazamine, Cisplatin, and Radiation versus Fluorouracil, Cisplatin, and Radiation in patients with locally advanced head and neck cancer: a randomized Phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02). J. Clin. Oncol. 2005, 23, 79-87.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 79-87
    • Rischin, D.1    Peters, L.2    Fisher, R.3    Macann, A.4    Denham, J.5
  • 99
    • 24644500678 scopus 로고    scopus 로고
    • Molecular mechanism of antitumor activity of taxanes in lung cancer
    • Zhao, J.; Kim, J.E.; Reed, E.; Li, Q.Q. Molecular mechanism of antitumor activity of taxanes in lung cancer (Review). Int. J. Oncol. 2005, 27, 247-256.
    • (2005) Int. J. Oncol. , vol.27 , pp. 247-256
    • Zhao, J.1    Kim, J.E.2    Reed, E.3    Li, Q.Q.4
  • 100
    • 0026684820 scopus 로고
    • Taxol sensitizes human astrocytoma cells to radiation
    • Tishler, R.B.; Geard, C.R.; Hall, E.J.; Schiff, P.B. Taxol sensitizes human astrocytoma cells to radiation. Cancer Res. 1992, 52, 3495-3497.
    • (1992) Cancer Res. , vol.52 , pp. 3495-3497
    • Tishler, R.B.1    Geard, C.R.2    Hall, E.J.3    Schiff, P.B.4
  • 102
    • 0034793702 scopus 로고    scopus 로고
    • Schedule-dependent pulsed paclitaxel radiosensitization for thoracic malignancy
    • Chen, Y.; Pandya, K.; Keng, P.P.; Feins, R.; Raubertas, R.; et al. Schedule-dependent pulsed paclitaxel radiosensitization for thoracic malignancy. Am J. Clin. Oncol. 2001, 24, 432-437.
    • (2001) Am J. Clin. Oncol. , vol.24 , pp. 432-437
    • Chen, Y.1    Pandya, K.2    Keng, P.P.3    Feins, R.4    Raubertas, R.5
  • 103
    • 0031917868 scopus 로고    scopus 로고
    • Phase I study of paclitaxel as a radiation sensitizer in the treatment of mesothelioma and non-small-cell lung cancer
    • Herscher, L.L.; Hahn, S.M.; Kroog, G.; Pass, H.; Temeck, B.; et al. Phase I study of paclitaxel as a radiation sensitizer in the treatment of mesothelioma and non-small-cell lung cancer. J. Clin. Oncol. 1998, 16, 635-641.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 635-641
    • Herscher, L.L.1    Hahn, S.M.2    Kroog, G.3    Pass, H.4    Temeck, B.5
  • 104
    • 0035863292 scopus 로고    scopus 로고
    • Twice-weekly paclitaxel and weekly carboplatin with concurrent thoracic radiation followed by carboplatin/paclitaxel consolidation for stage III non-small-cell lung cancer: A California Cancer Consortium Phase II trial
    • Lau, D.; Leigh, B.; Gandara, D.; Edelman, M.; Morgan, R.; et al. Twice-weekly paclitaxel and weekly carboplatin with concurrent thoracic radiation followed by carboplatin/paclitaxel consolidation for stage III non-small-cell lung cancer: a California Cancer Consortium Phase II trial. J. Clin. Oncol. 2001, 19, 442-447.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 442-447
    • Lau, D.1    Leigh, B.2    Gandara, D.3    Edelman, M.4    Morgan, R.5
  • 105
    • 0031726121 scopus 로고    scopus 로고
    • Multiinstitutional Phase II trial of paclitaxel, carboplatin, and concurrent radiation therapy for locally advanced non-small-cell lung cancer
    • Choy, H.; Akerley, W.; Safran, H.; Graziano, S.; Chung, C.; et al. Multiinstitutional Phase II trial of paclitaxel, carboplatin, and concurrent radiation therapy for locally advanced non-small-cell lung cancer. J. Clin. Oncol. 1998, 16, 3316-3322.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 3316-3322
    • Choy, H.1    Akerley, W.2    Safran, H.3    Graziano, S.4    Chung, C.5
  • 106
    • 0031848532 scopus 로고    scopus 로고
    • Phase II trial of weekly paclitaxel and concurrent radiation therapy for locally advanced non-small cell lung cancer
    • Choy, H.; Safran, H.; Akerley, W.; Graziano, S.L.; Bogart, J.A.; et al. Phase II trial of weekly paclitaxel and concurrent radiation therapy for locally advanced non-small cell lung cancer. Clin. Cancer Res. 1998, 4, 1931-1936.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1931-1936
    • Choy, H.1    Safran, H.2    Akerley, W.3    Graziano, S.L.4    Bogart, J.A.5
  • 107
    • 0031201598 scopus 로고    scopus 로고
    • Seven-week continuous-infusion paclitaxel plus concurrent radiation therapy for locally advanced non-small cell lung cancer: A Phase I study
    • Rosenthal, D.I.; Okani, O.; Corak, J.; Kavanaugh, D.; Kamen, B.; et al. Seven-week continuous-infusion paclitaxel plus concurrent radiation therapy for locally advanced non-small cell lung cancer: a Phase I study. Semin. Oncol. 1997, 24, S12-96-S12-100.
    • (1997) Semin. Oncol. , vol.24
    • Rosenthal, D.I.1    Okani, O.2    Corak, J.3    Kavanaugh, D.4    Kamen, B.5
  • 108
    • 0037342884 scopus 로고    scopus 로고
    • Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: A therapeutic approach on the basis of preclinical research of human cancer cell lines
    • Chen, Y.; Pandya, K.; Keng, P.C.; Johnstone, D.; Li, J.; et al. Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: a therapeutic approach on the basis of preclinical research of human cancer cell lines. Clin. Cancer Res. 2003, 9, 969-975.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 969-975
    • Chen, Y.1    Pandya, K.2    Keng, P.C.3    Johnstone, D.4    Li, J.5
  • 109
    • 0034176128 scopus 로고    scopus 로고
    • The use of carboplatin and paclitaxel with daily radiotherapy in patients with locally advanced squamous cell carcinomas of the head and neck
    • Suntharalingam, M.; Haas, M.L.; Conley, B.A.; Egorin, M.J.; Levy, S.; et al. The use of carboplatin and paclitaxel with daily radiotherapy in patients with locally advanced squamous cell carcinomas of the head and neck. Int. J. Radiat. Oncol. Biol. Phys. 2000, 47 49-56.
    • (2000) Int. J. Radiat. Oncol. Biol. Phys. , vol.47 , pp. 49-56
    • Suntharalingam, M.1    Haas, M.L.2    Conley, B.A.3    Egorin, M.J.4    Levy, S.5
  • 110
    • 0036785451 scopus 로고    scopus 로고
    • A Phase I/II trial of concurrent docetaxel and radiation after induction chemotherapy in patients with poor prognosis squamous cell carcinoma of the head and neck
    • Tishler, R.B.; Norris, C.M.; Jr.; Colevas, A.D.; Lamb, C.C.; Karp, D.; et al. A Phase I/II trial of concurrent docetaxel and radiation after induction chemotherapy in patients with poor prognosis squamous cell carcinoma of the head and neck. Cancer 2002, 95, 1472-1481.
    • (2002) Cancer , vol.95 , pp. 1472-1481
    • Tishler, R.B.1    Norris Jr., C.M.2    Colevas, A.D.3    Lamb, C.C.4    Karp, D.5
  • 111
    • 0842330212 scopus 로고    scopus 로고
    • Combining EGFR inhibitors with radiation or chemotherapy: Will preclinical studies predict clinical results?
    • Harari, P.M.; Huang, S.M. Combining EGFR inhibitors with radiation or chemotherapy: will preclinical studies predict clinical results? Int. J. Radiat. Oncol. Biol. Phys. 2004, 58, 976-983.
    • (2004) Int. J. Radiat. Oncol. Biol. Phys. , vol.58 , pp. 976-983
    • Harari, P.M.1    Huang, S.M.2
  • 112
    • 0023196582 scopus 로고
    • erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells
    • Di Fiore, P.P.; Pierce, J.H.; Kraus, M.H.; Segatto, O.; King, C.R.; et al. erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science 1987, 237, 178-182.
    • (1987) Science , vol.237 , pp. 178-182
    • Di Fiore, P.P.1    Pierce, J.H.2    Kraus, M.H.3    Segatto, O.4    King, C.R.5
  • 113
    • 0033651234 scopus 로고    scopus 로고
    • The molecular and cellular biology of HER2/neu gene amplification/ overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer
    • Pegram, M.D.; Konecny, G.; Slamon, D.J. The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer. Cancer Treat. Res. 2000, 103, 57-75.
    • (2000) Cancer Treat. Res. , vol.103 , pp. 57-75
    • Pegram, M.D.1    Konecny, G.2    Slamon, D.J.3
  • 114
    • 10744229156 scopus 로고    scopus 로고
    • Expression of ErbB2 enhances radiation-induced NF-kappaB activation
    • Guo, G.; Wang, T.; Gao, Q.; Tamae, D.; Wong, P.; et al. Expression of ErbB2 enhances radiation-induced NF-kappaB activation. Oncogene 2004, 23, 535-545.
    • (2004) Oncogene , vol.23 , pp. 535-545
    • Guo, G.1    Wang, T.2    Gao, Q.3    Tamae, D.4    Wong, P.5
  • 115
    • 33745302101 scopus 로고    scopus 로고
    • Radiosensitization of locally advanced breast cancer with herceptin - Initial toxicity results of a phase II trial
    • Sartor, C.G.; M. Carey, L.; Dees, E.C.; Ollila, D.; Sherron, R.; et al. RADIOSENSITIZATION OF LOCALLY ADVANCED BREAST CANCER WITH HERCEPTIN - INITIAL TOXICITY RESULTS OF A PHASE II TRIAL. In: San Antonio Breast Cancer Meeting 2003.
    • (2003) San Antonio Breast Cancer Meeting
    • Sartor, C.G.1    M. Carey, L.2    Dees, E.C.3    Ollila, D.4    Sherron, R.5
  • 116
    • 19944427370 scopus 로고    scopus 로고
    • Trastuzumab, paclitaxel, cisplatin, and radiation for adenocarcinoma of the esophagus: A Phase I study
    • Safran, H.; DiPetrillo, T.; Nadeem, A.; Steinhoff, M.; Tantravahi, U.; et al. Trastuzumab, paclitaxel, cisplatin, and radiation for adenocarcinoma of the esophagus: a Phase I study. Cancer Invest. 2004, 22, 670-677.
    • (2004) Cancer Invest. , vol.22 , pp. 670-677
    • Safran, H.1    DiPetrillo, T.2    Nadeem, A.3    Steinhoff, M.4    Tantravahi, U.5
  • 117
    • 0034084314 scopus 로고    scopus 로고
    • Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
    • Huang, S.M.; Harari, P.M. Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin. Cancer Res. 2000, 6, 2166-2174.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2166-2174
    • Huang, S.M.1    Harari, P.M.2
  • 118
    • 19944427144 scopus 로고    scopus 로고
    • The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer
    • Raben, D.; Helfrich, B.; Chan, D.C.; Ciardiello, F.; Zhao, L.; et al. The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer. Clin. Cancer Res. 2005, 11, 795-805.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 795-805
    • Raben, D.1    Helfrich, B.2    Chan, D.C.3    Ciardiello, F.4    Zhao, L.5
  • 119
    • 1242270605 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and tumor response to radiation: In vivo preclinical studies
    • Milas, L.; Fan, Z.; Andratschke, N.H.; Ang, K.K. Epidermal growth factor receptor and tumor response to radiation: in vivo preclinical studies. Int. J. Radiat. Oncol. Biol. Phys. 2004, 58, 966-971.
    • (2004) Int. J. Radiat. Oncol. Biol. Phys. , vol.58 , pp. 966-971
    • Milas, L.1    Fan, Z.2    Andratschke, N.H.3    Ang, K.K.4
  • 120
    • 0037111274 scopus 로고    scopus 로고
    • Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation
    • Buchsbaum, D.J.; Bonner, J.A.; Grizzle, W.E.; Stackhouse, M.A.; Carpenter, M.; et al. Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation. Int. J. Radiat. Oncol. Biol. Phys. 2002, 54, 1180-1193.
    • (2002) Int. J. Radiat. Oncol. Biol. Phys. , vol.54 , pp. 1180-1193
    • Buchsbaum, D.J.1    Bonner, J.A.2    Grizzle, W.E.3    Stackhouse, M.A.4    Carpenter, M.5
  • 121
    • 10244243722 scopus 로고    scopus 로고
    • Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma
    • Maurizi, M.; Almadori, G.; Ferrandina, G.; Distefano, M.; Romanini, M.E.; et al. Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma. Br. J. Cancer 1996, 74, 1253-1257.
    • (1996) Br. J. Cancer , vol.74 , pp. 1253-1257
    • Maurizi, M.1    Almadori, G.2    Ferrandina, G.3    Distefano, M.4    Romanini, M.E.5
  • 122
    • 24944479590 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial
    • Bentzen, S.M.; Atasoy, B.M.; Daley, F.M.; Dische, S.; Richman, P.I.; et al. Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial. J. Clin. Oncol. 2005, 23, 5560-5567.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 5560-5567
    • Bentzen, S.M.1    Atasoy, B.M.2    Daley, F.M.3    Dische, S.4    Richman, P.I.5
  • 123
    • 0035398021 scopus 로고    scopus 로고
    • Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer
    • Robert, F.; Ezekiel, M.P.; Spencer, S.A.; Meredith, R.F.; Bonner, J.A.; et al. Phase I study of anti-epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer. J. Clin. Oncol. 2001, 19, 3234-3243.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3234-3243
    • Robert, F.1    Ezekiel, M.P.2    Spencer, S.A.3    Meredith, R.F.4    Bonner, J.A.5
  • 124
    • 0034895886 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer
    • Shin, D.M.; Donato, N.J.; Perez-Soler, R.; Shin, H.J.; Wu, J.Y.; et al. Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer. Clin. Cancer Res. 2001, 7, 1204-1213.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1204-1213
    • Shin, D.M.1    Donato, N.J.2    Perez-Soler, R.3    Shin, H.J.4    Wu, J.Y.5
  • 125
    • 10444220480 scopus 로고    scopus 로고
    • Cetuximab prolongs survival in patients with locally advanced squamous cell carcinoma of head and neck: A Phase III study of high dose radiation therapy with or without cetuximab
    • Bonner, J.G.; J. Harari, P.; et al. Cetuximab prolongs survival in patients with locally advanced squamous cell carcinoma of head and neck: a Phase III study of high dose radiation therapy with or without cetuximab. In: ASCO Annual Meeting Proceedings (Post-Meeting Edition) 2004.
    • (2004) ASCO Annual Meeting Proceedings (Post-Meeting Edition)
    • Bonner, J.G.1    J. Harari, P.2
  • 126
    • 33745296956 scopus 로고    scopus 로고
    • Personal Communication
    • Safran, H. Personal Communication, 2005.
    • (2005)
    • Safran, H.1
  • 127
    • 0141568003 scopus 로고    scopus 로고
    • The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 selectively potentiates radiation response of human tumors in nude mice, with a marked improvement in therapeutic index
    • She, Y.; Lee, F.; Chen, J.; Haimovitz-Friedman, A.; Miller, V.A.; et al. The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 selectively potentiates radiation response of human tumors in nude mice, with a marked improvement in therapeutic index. Clin. Cancer Res. 2003, 9, 3773-3778.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 3773-3778
    • She, Y.1    Lee, F.2    Chen, J.3    Haimovitz-Friedman, A.4    Miller, V.A.5
  • 128
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • Kobayashi, S.; Boggon, T.J.; Dayaram, T.; Janne, P.A.; Kocher, O.; et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 2005, 352, 786-792.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 786-792
    • Kobayashi, S.1    Boggon, T.J.2    Dayaram, T.3    Janne, P.A.4    Kocher, O.5
  • 129
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao, W.; Miller, V.; Zakowski, M.; Doherty, J.; Politi, K.; et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 13306-13311.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3    Doherty, J.4    Politi, K.5
  • 130
    • 4143066760 scopus 로고    scopus 로고
    • Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
    • Sordella, R.; Bell, D.W.; Haber, D.A.; Settleman, J. Gefitinib- sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 2004, 305, 1163-1167.
    • (2004) Science , vol.305 , pp. 1163-1167
    • Sordella, R.1    Bell, D.W.2    Haber, D.A.3    Settleman, J.4
  • 131
    • 17144371349 scopus 로고    scopus 로고
    • Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva)
    • Chinnaiyan, P.; Huang, S.; Vallabhaneni, G.; Armstrong, E.; Varambally, S.; et al. Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva). Cancer Res. 2005, 65, 3328-3335.
    • (2005) Cancer Res. , vol.65 , pp. 3328-3335
    • Chinnaiyan, P.1    Huang, S.2    Vallabhaneni, G.3    Armstrong, E.4    Varambally, S.5
  • 132
    • 0030774045 scopus 로고    scopus 로고
    • Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
    • Moyer, J.D.; Barbacci, E.G.; Iwata, K.K.; Arnold, L.; Boman, B.; et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997, 57, 4838-4848.
    • (1997) Cancer Res. , vol.57 , pp. 4838-4848
    • Moyer, J.D.1    Barbacci, E.G.2    Iwata, K.K.3    Arnold, L.4    Boman, B.5
  • 133
    • 0037667417 scopus 로고    scopus 로고
    • Preclinical studies with Erlotinib (Tarceva)
    • Akita, R.W.; Sliwkowski, M.X. Preclinical studies with Erlotinib (Tarceva). Semin. Oncol. 2003, 30, 15-24.
    • (2003) Semin. Oncol. , vol.30 , pp. 15-24
    • Akita, R.W.1    Sliwkowski, M.X.2
  • 134
    • 2942511506 scopus 로고    scopus 로고
    • Antitumor activity of erlotinib (OSI-774, Tarceva) alone or in combination in human non-small cell lung cancer tumor xenograft models
    • Higgins, B.; Kolinsky, K.; Smith, M.; Beck, G.; Rashed, M.; et al. Antitumor activity of erlotinib (OSI-774, Tarceva) alone or in combination in human non-small cell lung cancer tumor xenograft models. Anticancer Drugs 2004, 15, 503-512.
    • (2004) Anticancer Drugs , vol.15 , pp. 503-512
    • Higgins, B.1    Kolinsky, K.2    Smith, M.3    Beck, G.4    Rashed, M.5
  • 135
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz, H.; Fehrenbacher, L.; Novotny, W.; Cartwright, T.; Hainsworth, J.; et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 2004, 350, 2335-2342.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3    Cartwright, T.4    Hainsworth, J.5
  • 136
    • 33644974427 scopus 로고    scopus 로고
    • Phase I Trial of Bevacizumab (BV) with Concurrent Radiotherapy (RT) and Capecitabine (CAP) in Locally Advanced Pancreatic Adenccarcinoma (PA)
    • Crane, C.E.; Abbruzzese, L.M.; Douglas, J.L.; Henry, E.B.; Ho, X.; et al. Phase I Trial of Bevacizumab (BV) with Concurrent Radiotherapy (RT) and Capecitabine (CAP) in Locally Advanced Pancreatic Adenccarcinoma (PA). In: Proc ASCO 2005.
    • (2005) Proc ASCO
    • Crane, C.E.1    Abbruzzese, L.M.2    Douglas, J.L.3    Henry, E.B.4    Ho, X.5
  • 137
    • 0035341494 scopus 로고    scopus 로고
    • Enhancement of radiosensitivity by proteasome inhibition: Implications for a role of NF-kappaB
    • Russo, S.M.; Tepper, J.E.; Baldwin, A.S.; Jr.; Liu, R.; Adams, J.; et al. Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB. Int. J. Radiat. Oncol. Biol. Phys. 2001, 50, 183-193.
    • (2001) Int. J. Radiat. Oncol. Biol. Phys. , vol.50 , pp. 183-193
    • Russo, S.M.1    Tepper, J.E.2    Baldwin Jr., A.S.3    Liu, R.4    Adams, J.5
  • 138
    • 27744515028 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-kappaB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma
    • Van Waes, C.; Chang, A.A.; Lebowitz, P.F.; Druzgal, C.H.; Chen, Z.; et al. Inhibition of nuclear factor-kappaB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 2005.
    • (2005) Int. J. Radiat. Oncol. Biol. Phys.
    • Van Waes, C.1    Chang, A.A.2    Lebowitz, P.F.3    Druzgal, C.H.4    Chen, Z.5
  • 139
    • 0035370755 scopus 로고    scopus 로고
    • Selective radioprotection of hepatocytes by systemic and portal vein infusions of amifostine in a rat liver tumor model
    • Symon, Z.; Levi, M.; Ensminger, W.D.; Smith, D.E.; Lawrence, T.S. Selective radioprotection of hepatocytes by systemic and portal vein infusions of amifostine in a rat liver tumor model. Int. J. Radiat. Oncol. Biol. Phys. 2001, 50, 473-478.
    • (2001) Int. J. Radiat. Oncol. Biol. Phys. , vol.50 , pp. 473-478
    • Symon, Z.1    Levi, M.2    Ensminger, W.D.3    Smith, D.E.4    Lawrence, T.S.5
  • 140
    • 12144286602 scopus 로고    scopus 로고
    • Effects of amifostine on acute toxicity from concurrent chemotherapy and radiotherapy for inoperable non-small-cell lung cancer: Report of a randomized comparative trial
    • Komaki, R.; Lee, J.S.; Milas, L.; Lee, H.K.; Fossella, F.V.; et al. Effects of amifostine on acute toxicity from concurrent chemotherapy and radiotherapy for inoperable non-small-cell lung cancer: report of a randomized comparative trial. Int. J. Radiat. Oncol. Biol. Phys. 2004, 55, 1369-1377.
    • (2004) Int. J. Radiat. Oncol. Biol. Phys. , vol.55 , pp. 1369-1377
    • Komaki, R.1    Lee, J.S.2    Milas, L.3    Lee, H.K.4    Fossella, F.V.5
  • 141
    • 20244383481 scopus 로고    scopus 로고
    • Randomized trial of amifostine in locally advanced non-small-cell lung cancer patients receiving chemotherapy and hyperfractionated radiation: Radiation therapy oncology group trial 98-01
    • Movsas, B.; Scott, C.; Langer, C.; Werner-Wasik, M.; Nicolaou, N.; et al. Randomized trial of amifostine in locally advanced non-small-cell lung cancer patients receiving chemotherapy and hyperfractionated radiation: radiation therapy oncology group trial 98-01. J. Clin. Oncol. 2005, 23, 2145-2154.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 2145-2154
    • Movsas, B.1    Scott, C.2    Langer, C.3    Werner-Wasik, M.4    Nicolaou, N.5
  • 142
    • 13844275190 scopus 로고    scopus 로고
    • The role of amifostine in the treatment of carcinoma of the uterine cervix: An update of RTOG-0116 and review of future directions
    • De Los Santos, J.F.; Small, W. The role of amifostine in the treatment of carcinoma of the uterine cervix: an update of RTOG-0116 and review of future directions. Semin. Oncol. 2004, 31, 37-41.
    • (2004) Semin. Oncol. , vol.31 , pp. 37-41
    • De Los Santos, J.F.1    Small, W.2
  • 143
    • 0036126435 scopus 로고    scopus 로고
    • Intrarectal application of amifostine for the prevention of radiation-induced rectal injury
    • Ben-Josef, E.; Han, S.; Tobi, M.; Vargas, B.J.; Stamos, B.; et al. Intrarectal application of amifostine for the prevention of radiation-induced rectal injury. Semin Radiat. Oncol. 2002, 12, 81-85.
    • (2002) Semin Radiat. Oncol. , vol.12 , pp. 81-85
    • Ben-Josef, E.1    Han, S.2    Tobi, M.3    Vargas, B.J.4    Stamos, B.5
  • 144
    • 1642517270 scopus 로고    scopus 로고
    • Clinical trial of endorectal amifostine for radioprotection in patients with prostate cancer: Rationale and early results
    • Menard, C.; Camphausen, K.; Muanza, T.; Sears-Crouse, N.; Smith, S.; et al. Clinical trial of endorectal amifostine for radioprotection in patients with prostate cancer: rationale and early results. Semin. Oncol. 2003, 30, 63-67.
    • (2003) Semin. Oncol. , vol.30 , pp. 63-67
    • Menard, C.1    Camphausen, K.2    Muanza, T.3    Sears-Crouse, N.4    Smith, S.5
  • 145
    • 14844292125 scopus 로고    scopus 로고
    • Pretreatment anemia is correlated with the reduced effectiveness of radiation and concurrent chemotherapy in advanced head and neck cancer
    • Prosnitz, R.G.; Yao, B.; Farrell, C.L.; Clough, R.; Brizel, D.M. Pretreatment anemia is correlated with the reduced effectiveness of radiation and concurrent chemotherapy in advanced head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys. 2005, 61, 1087-1095.
    • (2005) Int. J. Radiat. Oncol. Biol. Phys. , vol.61 , pp. 1087-1095
    • Prosnitz, R.G.1    Yao, B.2    Farrell, C.L.3    Clough, R.4    Brizel, D.M.5
  • 146
    • 0024802411 scopus 로고
    • The role of hemoglobin concentration in the outcome of misonidazole-sensitized radiotherapy of head and neck cancers: Based on RTOG trial #79-15
    • Fazekas, J.T.; Scott, C.; Marcial, V.; Davis, L.W.; Wasserman, T.; et al. The role of hemoglobin concentration in the outcome of misonidazole-sensitized radiotherapy of head and neck cancers: based on RTOG trial #79-15. Int. J. Radiat. Oncol. Biol. Phys. 1989, 17, 1177-1181.
    • (1989) Int. J. Radiat. Oncol. Biol. Phys. , vol.17 , pp. 1177-1181
    • Fazekas, J.T.1    Scott, C.2    Marcial, V.3    Davis, L.W.4    Wasserman, T.5
  • 147
    • 0026608117 scopus 로고
    • The prognostic value of hemoglobin and a decrease in hemoglobin during radiotherapy in laryngeal carcinoma
    • van Acht, M.J.; Hermans, J.; Boks, D.E.; Leer, J.W. The prognostic value of hemoglobin and a decrease in hemoglobin during radiotherapy in laryngeal
    • (1992) Radiother Oncol. , vol.23 , pp. 229-235
    • Van Acht, M.J.1    Hermans, J.2    Boks, D.E.3    Leer, J.W.4
  • 148
    • 0034819345 scopus 로고    scopus 로고
    • Predictive value of the tumor oxygenation by means of pO2 histography in patients with advanced head and neck cancer
    • Rudat, V.; Stadler, P.; Becker, A.; Vanselow, B.; Dietz, A.; et al. Predictive value of the tumor oxygenation by means of pO2 histography in patients with advanced head and neck cancer. Strahlenther Onkol. 2001, 177, 462-468.
    • (2001) Strahlenther Onkol. , vol.177 , pp. 462-468
    • Rudat, V.1    Stadler, P.2    Becker, A.3    Vanselow, B.4    Dietz, A.5
  • 149
    • 0032708195 scopus 로고    scopus 로고
    • Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
    • Brizel, D.M.; Dodge, R.K.; Clough, R.W.; Dewhirst, M.W. Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome. Radiother Oncol. 1999, 53, 113-117.
    • (1999) Radiother Oncol. , vol.53 , pp. 113-117
    • Brizel, D.M.1    Dodge, R.K.2    Clough, R.W.3    Dewhirst, M.W.4
  • 150
    • 0034307045 scopus 로고    scopus 로고
    • Anemia, hypoxia and transfusion in patients with cervix cancer: A review
    • Fyles, A.W.; Milosevic, M.; Pintilie, M.; Syed, A.; Hill, R.P. Anemia, hypoxia and transfusion in patients with cervix cancer: a review. Radiother Oncol. 2000, 57, 13-19.
    • (2000) Radiother Oncol. , vol.57 , pp. 13-19
    • Fyles, A.W.1    Milosevic, M.2    Pintilie, M.3    Syed, A.4    Hill, R.P.5
  • 151
    • 0142186283 scopus 로고    scopus 로고
    • Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomised, double-blind, placebo-controlled trial
    • Henke, M.; Laszig, R.; Rube, C.; Schafer, U.; Haase, K.D.; et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet. 2003, 362, 1255-1260.
    • (2003) Lancet , vol.362 , pp. 1255-1260
    • Henke, M.1    Laszig, R.2    Rube, C.3    Schafer, U.4    Haase, K.D.5
  • 152
    • 21744451644 scopus 로고    scopus 로고
    • Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma
    • Lai, S.Y.; Childs, E.E.; Xi, S.; Coppelli, F.M.; Gooding, W.E.; et al. Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma. Oncogene 2005, 24, 4442-4449.
    • (2005) Oncogene , vol.24 , pp. 4442-4449
    • Lai, S.Y.1    Childs, E.E.2    Xi, S.3    Coppelli, F.M.4    Gooding, W.E.5
  • 153
    • 12344335676 scopus 로고    scopus 로고
    • Erythropoietin induces cancer cell resistance to ionizing radiation and to cisplatin
    • Belenkov, A.I.; Shenouda, G.; Rizhevskaya, E.; Cournoyer, D.; Belzile, J.P.; et al. Erythropoietin induces cancer cell resistance to ionizing radiation and to cisplatin. Mol. Cancer Ther. 2004, 3, 1525-1532.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 1525-1532
    • Belenkov, A.I.1    Shenouda, G.2    Rizhevskaya, E.3    Cournoyer, D.4    Belzile, J.P.5
  • 154
    • 0025043987 scopus 로고
    • Human tumor fluorouracil trapping: Clinical correlations of in vivo 19F nuclear magnetic resonance spectroscopy pharmacokinetics
    • Presant, C.A.; Wolf, W.; Albright, M.J.; Servis, K. L.; Ring, R.; 3rd, et al. Human tumor fluorouracil trapping: clinical correlations of in vivo 19F nuclear magnetic resonance spectroscopy pharmacokinetics. J. Clin. Oncol. 1990, 8, 1868-1873.
    • (1990) J. Clin. Oncol. , vol.8 , pp. 1868-1873
    • Presant, C.A.1    Wolf, W.2    Albright, M.J.3    Servis, K.L.4    Ring III, R.5
  • 155
    • 8744228288 scopus 로고    scopus 로고
    • Active and inactive conformations of the epidermal growth factor receptor
    • Ferguson, K.M. Active and inactive conformations of the epidermal growth factor receptor. Biochem. Soc. Trans. 2004, 32, 742-745.
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 742-745
    • Ferguson, K.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.