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Volumn 64, Issue 2, 2006, Pages 551-561

Tumor radiosensitizers - Current status of development of various approaches: Report of an International Atomic Energy Agency meeting

Author keywords

IAEA; Meeting report; Radiosensitizers; Tumors

Indexed keywords

CELL SIGNALING PATHWAYS; IAEA; MEETING REPORT; RADIOSENSITIZERS;

EID: 30544450340     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2005.09.032     Document Type: Conference Paper
Times cited : (34)

References (102)
  • 1
    • 0037270737 scopus 로고    scopus 로고
    • The mechanism of action of radiosensitization of conventional chemotherapeutic agents
    • T.S. Lawrence, A.W. Blackstock, C. McGinn The mechanism of action of radiosensitization of conventional chemotherapeutic agents Semin Radiat Oncol 13 2003 13 21
    • (2003) Semin Radiat Oncol , vol.13 , pp. 13-21
    • Lawrence, T.S.1    Blackstock, A.W.2    McGinn, C.3
  • 2
    • 0033194695 scopus 로고    scopus 로고
    • Chemo-radiotherapy: Radiosensitizing nucleoside analogues
    • V. Gregoire, W.N. Hittelman, J.F. Rosier Chemo-radiotherapy Radiosensitizing nucleoside analogues Oncol Reps 6 1999 949 957
    • (1999) Oncol Reps , vol.6 , pp. 949-957
    • Gregoire, V.1    Hittelman, W.N.2    Rosier, J.F.3
  • 3
    • 0033028180 scopus 로고    scopus 로고
    • The effect of 2′-2′ difluoro-deoxycytidine on radiation-induced cell lethality in two human head and neck squamous carcinoma cell lines differing in intrinsic radiosensitivity
    • J.F. Rosier, M. Beauduin, M. Bruniaux The effect of 2′-2′ difluoro-deoxycytidine on radiation-induced cell lethality in two human head and neck squamous carcinoma cell lines differing in intrinsic radiosensitivity Int J Radiat Biol 75 1999 245 251
    • (1999) Int J Radiat Biol , vol.75 , pp. 245-251
    • Rosier, J.F.1    Beauduin, M.2    Bruniaux, M.3
  • 5
    • 0038023073 scopus 로고    scopus 로고
    • The radioenhancement of two human head and neck squamous carcinoma cell lines by 2′-2′ difluoro-deoxycytidine is mediated by an increase in radiation-induced residual chromosome aberrations but not residual DNA DSBs
    • J.F. Rosier, L. Michaux, G. Ameye The radioenhancement of two human head and neck squamous carcinoma cell lines by 2′-2′ difluoro- deoxycytidine is mediated by an increase in radiation-induced residual chromosome aberrations but not residual DNA DSBs Mut Res Fund Mol Mech Mutag 527 2003 15 26
    • (2003) Mut Res Fund Mol Mech Mutag , vol.527 , pp. 15-26
    • Rosier, J.F.1    Michaux, L.2    Ameye, G.3
  • 6
    • 0842281708 scopus 로고    scopus 로고
    • Role of 2′-2′ difluoro-deoxycytidine (gemcitabine)-induced cell cycle dysregulation in radio-enhancement of human head and neck squamous cell carcinomas
    • J.F. Rosier, M. Bruniaux, B. Husson Role of 2′-2′ difluoro-deoxycytidine (gemcitabine)-induced cell cycle dysregulation in radio-enhancement of human head and neck squamous cell carcinomas Radiother Oncol 70 2004 55 61
    • (2004) Radiother Oncol , vol.70 , pp. 55-61
    • Rosier, J.F.1    Bruniaux, M.2    Husson, B.3
  • 8
    • 0030751501 scopus 로고    scopus 로고
    • Enhancement of radiation-induced regrowth delay by gemcitabine in a human tumour xenograft model
    • M.A. Joschko, L.K. Webster, J. Grover Enhancement of radiation-induced regrowth delay by gemcitabine in a human tumour xenograft model Radiat Oncol Invest 5 1997 62 71
    • (1997) Radiat Oncol Invest , vol.5 , pp. 62-71
    • Joschko, M.A.1    Webster, L.K.2    Grover, J.3
  • 9
    • 0034214240 scopus 로고    scopus 로고
    • Radiosensitization produced in vivo by once vs. twice-weekly 2′-2′ difluoro-deoxycytidine (gemcitabine)
    • M.T. Fields, A. Eisbrush, D. Normolle Radiosensitization produced in vivo by once vs. twice-weekly 2′-2′ difluoro-deoxycytidine (gemcitabine) Int J Radiat Oncol Biol Phys 47 2000 785 791
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 785-791
    • Fields, M.T.1    Eisbrush, A.2    Normolle, D.3
  • 10
    • 0034880544 scopus 로고    scopus 로고
    • Combining gemcitabine with radiation in pancreatic cancer: Understanding important variables influencing the therapeutic index
    • C.H. Crane, R.A. Wolf, J.L. Abbruzzese Combining gemcitabine with radiation in pancreatic cancer Understanding important variables influencing the therapeutic index Semin Oncol 28 Suppl. 10 2001 25 33
    • (2001) Semin Oncol , vol.28 , Issue.10 SUPPL. , pp. 25-33
    • Crane, C.H.1    Wolf, R.A.2    Abbruzzese, J.L.3
  • 11
    • 0036570253 scopus 로고    scopus 로고
    • Effect of gemcitabine on acute and late radiation toxicity of skin and underlying soft tissues to single-dose irradiation in a nude mice model
    • J. Classen, F. Paulsen, T. Hehr Effect of gemcitabine on acute and late radiation toxicity of skin and underlying soft tissues to single-dose irradiation in a nude mice model Int J Radiat Oncol Biol Phys 53 2002 197 205
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 197-205
    • Classen, J.1    Paulsen, F.2    Hehr, T.3
  • 12
    • 0345104352 scopus 로고    scopus 로고
    • Effect of gemcitabine on the tolerance of the lung to single-dose irradiation in CH3 mice
    • V. Gregoire, S. Svilic, M. Beauduin Effect of gemcitabine on the tolerance of the lung to single-dose irradiation in CH3 mice Radiat Res 151 1999 747 749
    • (1999) Radiat Res , vol.151 , pp. 747-749
    • Gregoire, V.1    Svilic, S.2    Beauduin, M.3
  • 13
    • 0042566185 scopus 로고    scopus 로고
    • Concurrent chemoradiotherapy treatment of locally advanced pancreatic cancer: Gemcitabine vs. 5-fluorouracil, a randomized controlled study
    • C.P. Li, Y. Chao, K.H. Chi Concurrent chemoradiotherapy treatment of locally advanced pancreatic cancer Gemcitabine vs. 5-fluorouracil, a randomized controlled study Int J Radiat Oncol Biol Phys 57 2003 98 104
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , pp. 98-104
    • Li, C.P.1    Chao, Y.2    Chi, K.H.3
  • 14
    • 0033022613 scopus 로고    scopus 로고
    • Phase I trial of twice-weekly gemcitabine and concurrent radiation in patients with advanced pancreatic cancer
    • A.W. Blackstock, S.A. Bernard, F. Richards Phase I trial of twice-weekly gemcitabine and concurrent radiation in patients with advanced pancreatic cancer J Clin Oncol 17 1999 2208 2212
    • (1999) J Clin Oncol , vol.17 , pp. 2208-2212
    • Blackstock, A.W.1    Bernard, S.A.2    Richards, F.3
  • 15
    • 0038155152 scopus 로고    scopus 로고
    • A phase I study of gemcitabine with concurrent radiotherapy in stage III locally advanced non-small cell lung cancer
    • J.W.G. van Putten, A. Price, A.H.D. van der Leest A phase I study of gemcitabine with concurrent radiotherapy in stage III locally advanced non-small cell lung cancer Clin Cancer Res 9 2003 2472 2477
    • (2003) Clin Cancer Res , vol.9 , pp. 2472-2477
    • Van Putten, J.W.G.1    Price, A.2    Van Der Leest, A.H.D.3
  • 16
    • 0034980415 scopus 로고    scopus 로고
    • Phase II study of concurrent gemcitabine and radiotherapy in locally advanced stage IIIB cervical carcinoma
    • P. Pattaranutaporn, C. Thirapakawong, Y. Chansilpa Phase II study of concurrent gemcitabine and radiotherapy in locally advanced stage IIIB cervical carcinoma Gynecol Oncol 81 2001 404 407
    • (2001) Gynecol Oncol , vol.81 , pp. 404-407
    • Pattaranutaporn, P.1    Thirapakawong, C.2    Chansilpa, Y.3
  • 17
    • 0035253713 scopus 로고    scopus 로고
    • Radiation concurrent with gemcitabine for locally advanced head and neck cancer: A phase I trial and intracellular drug incorporation study
    • A. Eisbruch, D.S. Shewach, C.R. Bradford Radiation concurrent with gemcitabine for locally advanced head and neck cancer A phase I trial and intracellular drug incorporation study J Clin Oncol 19 2001 792 799
    • (2001) J Clin Oncol , vol.19 , pp. 792-799
    • Eisbruch, A.1    Shewach, D.S.2    Bradford, C.R.3
  • 18
    • 0242299702 scopus 로고    scopus 로고
    • Inhibition of DNA repair by pentoxifylline and related methylxanthine derivatives
    • L. Bohm, W.P. Roos, A.M. Serafin Inhibition of DNA repair by pentoxifylline and related methylxanthine derivatives Toxicology 193 2003 153 160
    • (2003) Toxicology , vol.193 , pp. 153-160
    • Bohm, L.1    Roos, W.P.2    Serafin, A.M.3
  • 19
    • 0028203515 scopus 로고
    • Is pentoxifylline the drug of the decade?
    • H. Ely Is pentoxifylline the drug of the decade? J Am Acad Dermatol 30 1994 603 621
    • (1994) J Am Acad Dermatol , vol.30 , pp. 603-621
    • Ely, H.1
  • 20
    • 0027442028 scopus 로고
    • Pentoxifylline: Its pharmacokinetics and ability to improve tumour perfusion and radiosensitivity in mice
    • D.J. Honess, I.F. Dennis, N.M. Bleehen Pentoxifylline Its pharmacokinetics and ability to improve tumour perfusion and radiosensitivity in mice Radiother Oncol 28 1993 208 218
    • (1993) Radiother Oncol , vol.28 , pp. 208-218
    • Honess, D.J.1    Dennis, I.F.2    Bleehen, N.M.3
  • 21
    • 0033764934 scopus 로고    scopus 로고
    • Pentoxifylline improves the oxygenation and radiation response of BA1112 rat rhabdomyosarcomas and EMT6 mouse mammary carcinomas
    • D.R. Collingridge, S. Rockwell Pentoxifylline improves the oxygenation and radiation response of BA1112 rat rhabdomyosarcomas and EMT6 mouse mammary carcinomas Int J Cancer 90 2000 256 264
    • (2000) Int J Cancer , vol.90 , pp. 256-264
    • Collingridge, D.R.1    Rockwell, S.2
  • 22
    • 2442681660 scopus 로고    scopus 로고
    • Pentoxifylline enhances tumour oxygenation and radiosensitivity in a rhabdomyosarcoma during continuous hyperfractionated irradiation
    • F. Zywietz, L. Bohm, C. Sagowski, W. Kehrl Pentoxifylline enhances tumour oxygenation and radiosensitivity in a rhabdomyosarcoma during continuous hyperfractionated irradiation Strahlenther Onkol 180 2004 306 314
    • (2004) Strahlenther Onkol , vol.180 , pp. 306-314
    • Zywietz, F.1    Bohm, L.2    Sagowski, C.3    Kehrl, W.4
  • 25
    • 0033653311 scopus 로고    scopus 로고
    • 2/M phase block enhances the cytotoxicity of daunorubicin, melphalan and cisplatin to p53 mutant human tumour cells
    • 2/M phase block enhances the cytotoxicity of daunorubicin, melphalan and cisplatin to p53 mutant human tumour cells Radiat Res 154 2000 640 649
    • (2000) Radiat Res , vol.154 , pp. 640-649
    • Binder, A.1    Serafin, A.M.2    Bohm, L.3
  • 26
    • 0030458483 scopus 로고    scopus 로고
    • Preferential radiosensitization of G1 checkpoint deficient cells by methylxanthanines
    • K.J. Russel, L.W. Wiens, G.W. Demers Preferential radiosensitization of G1 checkpoint deficient cells by methylxanthanines Int J Radiat Oncol Biol Phys 36 1996 1099 1106
    • (1996) Int J Radiat Oncol Biol Phys , vol.36 , pp. 1099-1106
    • Russel, K.J.1    Wiens, L.W.2    Demers, G.W.3
  • 27
    • 0034706917 scopus 로고    scopus 로고
    • Homologous recombination is a potential target for caffeine radiosensitization in mammalian cells reduced caffeine radiosensitization in XRSS2 and XRSS3 mutants
    • N.A. Asaad, Z. Zeng, J. Guan Homologous recombination is a potential target for caffeine radiosensitization in mammalian cells reduced caffeine radiosensitization in XRSS2 and XRSS3 mutants Oncogene 129 2000 5788 5800
    • (2000) Oncogene , vol.129 , pp. 5788-5800
    • Asaad, N.A.1    Zeng, Z.2    Guan, J.3
  • 28
    • 0033851791 scopus 로고    scopus 로고
    • 2 block abrogation, DNA double strand break repair and apoptosis in the radiosensitization of melanoma and squamous cell carcinoma cell lines
    • 2 block abrogation, DNA double strand break repair and apoptosis in the radiosensitization of melanoma and squamous cell carcinoma cell lines Int J Radiat Biol 76 2000 1197 1208
    • (2000) Int J Radiat Biol , vol.76 , pp. 1197-1208
    • Theron, T.1    Binder, A.2    Verheye-Dua, F.3
  • 29
    • 0242311016 scopus 로고    scopus 로고
    • RNA-polymerase II stalled on a DNA template during transcription elongation is ubiquitinated and the ubiquitination facilitates displacement of the elongation complex
    • L.Y. Yang, H. Jiang, K.M. Rangel RNA-polymerase II stalled on a DNA template during transcription elongation is ubiquitinated and the ubiquitination facilitates displacement of the elongation complex Int J Oncol 22 2003 683 689
    • (2003) Int J Oncol , vol.22 , pp. 683-689
    • Yang, L.Y.1    Jiang, H.2    Rangel, K.M.3
  • 30
  • 31
    • 14644407525 scopus 로고    scopus 로고
    • The role of apoptosis in cancer development and treatment response
    • J.M. Brown, L.D. Attardi The role of apoptosis in cancer development and treatment response Nat Rev Cancer 3 2005 231 237
    • (2005) Nat Rev Cancer , vol.3 , pp. 231-237
    • Brown, J.M.1    Attardi, L.D.2
  • 32
    • 0942300643 scopus 로고    scopus 로고
    • Apoptosis modulating drugs in combination with radiotherapy - Current status and outlook
    • C. Belka, V. Jendrossek, M. Pruschy Apoptosis modulating drugs in combination with radiotherapy - current status and outlook Int J Radiat Oncol Biol Phys 58 2004 542 544
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 542-544
    • Belka, C.1    Jendrossek, V.2    Pruschy, M.3
  • 33
    • 0037131168 scopus 로고    scopus 로고
    • Alkyl-lysophospholipids induce apoptosis via raft-mediated endocytosis and inhibition of phosphatidylcholine synthesis
    • A.H. van der Luit, M. Budde, P. Ruurs Alkyl-lysophospholipids induce apoptosis via raft-mediated endocytosis and inhibition of phosphatidylcholine synthesis J Biol Chem 277 2002 39541 39547
    • (2002) J Biol Chem , vol.277 , pp. 39541-39547
    • Van Der Luit, A.H.1    Budde, M.2    Ruurs, P.3
  • 34
    • 0347537940 scopus 로고    scopus 로고
    • Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis
    • M. Verheij, R. Bose, X.H. Lin Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis Nature 380 1996 75 79
    • (1996) Nature , vol.380 , pp. 75-79
    • Verheij, M.1    Bose, R.2    Lin, X.H.3
  • 35
    • 0033563010 scopus 로고    scopus 로고
    • Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis
    • G.A. Ruiter, S.F. Zerp, H. Bartelink Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis Cancer Res 59 1999 2457 2463
    • (1999) Cancer Res , vol.59 , pp. 2457-2463
    • Ruiter, G.A.1    Zerp, S.F.2    Bartelink, H.3
  • 36
    • 0037331989 scopus 로고    scopus 로고
    • Anticancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway
    • G.A. Ruiter, S.F. Zerp, H. Bartelink Anticancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway Anticancer Drugs 14 2003 167 173
    • (2003) Anticancer Drugs , vol.14 , pp. 167-173
    • Ruiter, G.A.1    Zerp, S.F.2    Bartelink, H.3
  • 37
    • 30544451557 scopus 로고    scopus 로고
    • The oral alkyl-phosphocholine perifosine potentiates the antitumor effect of radiation in vitro and in vivo
    • S.R. Vink, J.H.M. Schellens, J. Engel The oral alkyl-phosphocholine perifosine potentiates the antitumor effect of radiation in vitro and in vivo Radiother Oncol 73 Suppl. 1 2004 S426
    • (2004) Radiother Oncol , vol.73 , Issue.1 SUPPL. , pp. 426
    • Vink, S.R.1    Schellens, J.H.M.2    Engel, J.3
  • 38
    • 0035254650 scopus 로고    scopus 로고
    • Alkyl-lysophospholipids as anti-cancer agents and enhancers of radiation-induced apoptosis
    • G.A. Ruiter, M. Verheij, S.F. Zerp Alkyl-lysophospholipids as anti-cancer agents and enhancers of radiation-induced apoptosis Int J Radiat Oncol Biol Phys 49 2001 415 419
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 415-419
    • Ruiter, G.A.1    Verheij, M.2    Zerp, S.F.3
  • 39
    • 4043128412 scopus 로고    scopus 로고
    • Phase I study of combined treatment with the oral alkyl-lysophospholipid (APL) perifosine and radiation in patients with advanced solid tumors
    • M. Verheij, S.R. Vink, J.H.M. Schellens Phase I study of combined treatment with the oral alkyl-lysophospholipid (APL) perifosine and radiation in patients with advanced solid tumors Proc Am Soc Clin Oncol 23 2004 3064
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 3064
    • Verheij, M.1    Vink, S.R.2    Schellens, J.H.M.3
  • 40
    • 0031054990 scopus 로고    scopus 로고
    • Epidermal growth factor receptor family and chemosensitization
    • J. Mendelsohn, Z. Fan Epidermal growth factor receptor family and chemosensitization J Natl Cancer Inst 89 1997 341 343
    • (1997) J Natl Cancer Inst , vol.89 , pp. 341-343
    • Mendelsohn, J.1    Fan, Z.2
  • 41
    • 0034104525 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily: Role as anticancer agents
    • S.B. Noonberg, C.C. Benz Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily Role as anticancer agents Drugs 59 2000 753 767
    • (2000) Drugs , vol.59 , pp. 753-767
    • Noonberg, S.B.1    Benz, C.C.2
  • 42
    • 0034793855 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) enzyme inhibitors as potential enhancers of tumor radioresponse
    • L. Milas Cyclooxygenase-2 (COX-2) enzyme inhibitors as potential enhancers of tumor radioresponse Semin Radiat Oncol 11 2001 290 299
    • (2001) Semin Radiat Oncol , vol.11 , pp. 290-299
    • Milas, L.1
  • 44
    • 0032478998 scopus 로고    scopus 로고
    • Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
    • J. Grandis, M. Melhem, W. Gooding Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival J Natl Cancer Inst 90 1998 824 832
    • (1998) J Natl Cancer Inst , vol.90 , pp. 824-832
    • Grandis, J.1    Melhem, M.2    Gooding, W.3
  • 45
    • 0037115674 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
    • K.K. Ang, B.A. Berkey, X. Tu Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma Cancer Res 62 2002 7350 7356
    • (2002) Cancer Res , vol.62 , pp. 7350-7356
    • Ang, K.K.1    Berkey, B.A.2    Tu, X.3
  • 46
    • 0033966576 scopus 로고    scopus 로고
    • In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody
    • L. Milas, K. Mason, N. Hunter In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody Clin Cancer Res 6 2000 701 708
    • (2000) Clin Cancer Res , vol.6 , pp. 701-708
    • Milas, L.1    Mason, K.2    Hunter, N.3
  • 47
    • 2342465600 scopus 로고    scopus 로고
    • Targeted therapies and radiation for the treatment of head and neck cancer: Are we making progress?
    • D. Raben, C. Bianco, L. Milas Targeted therapies and radiation for the treatment of head and neck cancer Are we making progress? Semin Radiat Oncol 14 2004 139 152
    • (2004) Semin Radiat Oncol , vol.14 , pp. 139-152
    • Raben, D.1    Bianco, C.2    Milas, L.3
  • 48
    • 10444220480 scopus 로고    scopus 로고
    • Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck: A phase III study of high dose radiation therapy with or without cetuximab
    • J.A. Bonner, J. Giralt, P.M. Harari Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck A phase III study of high dose radiation therapy with or without cetuximab Proc Am Soc Clin Oncol 23 2004 488
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 488
    • Bonner, J.A.1    Giralt, J.2    Harari, P.M.3
  • 49
    • 4444262578 scopus 로고    scopus 로고
    • COX-2 and its inhibition as a molecular target in the prevention and treatment of lung cancer
    • Z. Liao, L. Milas COX-2 and its inhibition as a molecular target in the prevention and treatment of lung cancer Expert Rev Anticancer Ther 4 2004 543 560
    • (2004) Expert Rev Anticancer Ther , vol.4 , pp. 543-560
    • Liao, Z.1    Milas, L.2
  • 50
    • 0141540687 scopus 로고    scopus 로고
    • Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: A rational advance?
    • H. Choy, L. Milas Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors A rational advance? J Natl Cancer Inst 95 2003 1440 1452
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1440-1452
    • Choy, H.1    Milas, L.2
  • 51
    • 0042631411 scopus 로고    scopus 로고
    • Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer
    • N.K. Altorki, R.S. Keresztes, J.L. Port Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer J Clin Oncol 21 2003 2645 2650
    • (2003) J Clin Oncol , vol.21 , pp. 2645-2650
    • Altorki, N.K.1    Keresztes, R.S.2    Port, J.L.3
  • 52
    • 20944447527 scopus 로고    scopus 로고
    • A phase I clinical trial of thoracic radiation and concurrent celecoxib for patients unfavourable performance status inoperable/unresectable non-small cell lung cancer
    • Z. Liao, R. Komaki, L. Milas A phase I clinical trial of thoracic radiation and concurrent celecoxib for patients unfavourable performance status inoperable/unresectable non-small cell lung cancer Clin Cancer Res 11 2005 3342 3348
    • (2005) Clin Cancer Res , vol.11 , pp. 3342-3348
    • Liao, Z.1    Komaki, R.2    Milas, L.3
  • 53
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • J. Folkman Role of angiogenesis in tumor growth and metastasis Semin Oncol 29 Suppl. 16 2002 15 18
    • (2002) Semin Oncol , vol.29 , Issue.16 SUPPL. , pp. 15-18
    • Folkman, J.1
  • 54
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • P. Vaupel, F. Kallinowski, P. Okunieff Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors A review Cancer Res 49 1989 6449 6465
    • (1989) Cancer Res , vol.49 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 55
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • A.L. Harris Hypoxia - a key regulatory factor in tumour growth Nat Rev Cancer 2 2002 38 47
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 56
    • 1842659804 scopus 로고    scopus 로고
    • The oxygen effect and the tumour microenvironment
    • G.G. Steel 3rd ed Edward Arnold London
    • M.R. Horsman, J. Overgaard The oxygen effect and the tumour microenvironment G.G. Steel Basic clinical radiobiology 3rd ed 2002 Edward Arnold London 158 168
    • (2002) Basic Clinical Radiobiology , pp. 158-168
    • Horsman, M.R.1    Overgaard, J.2
  • 57
    • 2242446580 scopus 로고    scopus 로고
    • Overcoming tumour radioresistance resulting from hypoxia
    • G.G. Steel 3rd ed Edward Arnold London
    • M.R. Horsman, J. Overgaard Overcoming tumour radioresistance resulting from hypoxia G.G. Steel Basic clinical radiobiology 3rd ed 2002 Edward Arnold London 169 181
    • (2002) Basic Clinical Radiobiology , pp. 169-181
    • Horsman, M.R.1    Overgaard, J.2
  • 58
    • 0028632781 scopus 로고
    • Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors
    • J. Overgaard Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors Oncol Res 6 1994 509 518
    • (1994) Oncol Res , vol.6 , pp. 509-518
    • Overgaard, J.1
  • 59
    • 0034254436 scopus 로고    scopus 로고
    • Radiosensitivity of human pancreatic cancer cells in vitro and in vivo, and the effect of a new hypoxic cell sensitizer, doranidazole
    • Y. Shimaboto, T. Kubota, K. Kishii Radiosensitivity of human pancreatic cancer cells in vitro and in vivo, and the effect of a new hypoxic cell sensitizer, doranidazole Radiother Oncol 56 2000 265 270
    • (2000) Radiother Oncol , vol.56 , pp. 265-270
    • Shimaboto, Y.1    Kubota, T.2    Kishii, K.3
  • 60
    • 0029123236 scopus 로고
    • Nicotinamide and other benzamide analogs as agents for overcoming hypoxic cell radiation resistance in tumours
    • M.R. Horsman Nicotinamide and other benzamide analogs as agents for overcoming hypoxic cell radiation resistance in tumours Acta Oncol 34 1995 571 587
    • (1995) Acta Oncol , vol.34 , pp. 571-587
    • Horsman, M.R.1
  • 62
    • 0038030600 scopus 로고    scopus 로고
    • Radiotherapy with or without mitomycin c in the treatment of locally advanced head and neck cancer: Results of the IAEA multicentre randomised trial
    • C. Grau, J.P. Agarwal, K. Jabeen Radiotherapy with or without mitomycin c in the treatment of locally advanced head and neck cancer Results of the IAEA multicentre randomised trial Radiother Oncol 67 2003 17 26
    • (2003) Radiother Oncol , vol.67 , pp. 17-26
    • Grau, C.1    Agarwal, J.P.2    Jabeen, K.3
  • 63
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumor hypoxia in cancer treatment
    • J.M. Brown, W.R. Wilson Exploiting tumor hypoxia in cancer treatment Nat Rev Cancer 4 2004 437 447
    • (2004) Nat Rev Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 64
    • 16644377045 scopus 로고    scopus 로고
    • Tirapazamine, cisplatin, and radiation versus fluorouracil, cisplatin, and radiation in patients with locally advanced head and neck cancer: A randomized phase II trial of the Trans-Tasman Radiation Oncology group (TROG 98.02)
    • D. Rischin, L. Peters, R. Fisher Tirapazamine, cisplatin, and radiation versus fluorouracil, cisplatin, and radiation in patients with locally advanced head and neck cancer A randomized phase II trial of the Trans-Tasman Radiation Oncology group (TROG 98.02) J Clin Oncol 23 2005 79 87
    • (2005) J Clin Oncol , vol.23 , pp. 79-87
    • Rischin, D.1    Peters, L.2    Fisher, R.3
  • 65
    • 0034029002 scopus 로고    scopus 로고
    • Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent
    • L.H. Patterson, S.R. McKeown, K. Ruparelia Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent Br J Cancer 82 2000 1984 1990
    • (2000) Br J Cancer , vol.82 , pp. 1984-1990
    • Patterson, L.H.1    McKeown, S.R.2    Ruparelia, K.3
  • 66
  • 67
    • 0038176480 scopus 로고    scopus 로고
    • Tumor response to ionizing radiation combined with angiogenesis or vascular targeting agents: Exploiting mechanisms of interaction
    • P. Wachsberger, R. Burd, A.P. Dicker Tumor response to ionizing radiation combined with angiogenesis or vascular targeting agents Exploiting mechanisms of interaction Clin Cancer Res 9 2003 1957 1971
    • (2003) Clin Cancer Res , vol.9 , pp. 1957-1971
    • Wachsberger, P.1    Burd, R.2    Dicker, A.P.3
  • 68
    • 0030971274 scopus 로고    scopus 로고
    • An antiangiogenic agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma
    • R. Murata, Y. Nishimura, M. Hiraoka An antiangiogenic agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma Int J Radiat Oncol Biol Phys 37 1997 1107 1113
    • (1997) Int J Radiat Oncol Biol Phys , vol.37 , pp. 1107-1113
    • Murata, R.1    Nishimura, Y.2    Hiraoka, M.3
  • 69
    • 0043025225 scopus 로고    scopus 로고
    • Arginine deiminase and other antiangiogenic agents inhibit unfavourable neuroblastoma growth: Potentiation by irradiation
    • H. Gong, C. Pottgen, G. Stuben Arginine deiminase and other antiangiogenic agents inhibit unfavourable neuroblastoma growth Potentiation by irradiation Int J Cancer 106 2003 723 728
    • (2003) Int J Cancer , vol.106 , pp. 723-728
    • Gong, H.1    Pottgen, C.2    Stuben, G.3
  • 70
    • 0036891440 scopus 로고    scopus 로고
    • Combination of vascular targeting agents with thermal and radiation therapy
    • M.R. Horsman, R. Murata Combination of vascular targeting agents with thermal and radiation therapy Int J Radiat Oncol Biol Phys 54 2002 1518 1523
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 1518-1523
    • Horsman, M.R.1    Murata, R.2
  • 71
    • 2642571660 scopus 로고    scopus 로고
    • Vascular targeting therapies for treatment of malignant disease
    • D.W. Siemann, D.J. Chaplin, M.R. Horsman Vascular targeting therapies for treatment of malignant disease Cancer 100 2004 2491 2499
    • (2004) Cancer , vol.100 , pp. 2491-2499
    • Siemann, D.W.1    Chaplin, D.J.2    Horsman, M.R.3
  • 72
    • 0035992688 scopus 로고    scopus 로고
    • Oblimersen Bcl-2 antisense: Facilitating apoptosis in anticancer treatment
    • R.J. Klasa, A.M. Gillum, R.E. Klem Oblimersen Bcl-2 antisense Facilitating apoptosis in anticancer treatment Antisense Nucleic Acid Drug Dev 12 2002 193 213
    • (2002) Antisense Nucleic Acid Drug Dev , vol.12 , pp. 193-213
    • Klasa, R.J.1    Gillum, A.M.2    Klem, R.E.3
  • 73
    • 0036846993 scopus 로고    scopus 로고
    • Antisense therapy for cancer - The time of truth
    • B. Jansen, U. Zangmeister Antisense therapy for cancer - The time of truth Lancet Oncol 3 2002 672 683
    • (2002) Lancet Oncol , vol.3 , pp. 672-683
    • Jansen, B.1    Zangmeister, U.2
  • 74
    • 0031045967 scopus 로고    scopus 로고
    • Bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells
    • N. Kyprianou, E.D. King, D. Bradbury Bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells Int J Cancer 70 1997 341 348
    • (1997) Int J Cancer , vol.70 , pp. 341-348
    • Kyprianou, N.1    King, E.D.2    Bradbury, D.3
  • 75
    • 0031762429 scopus 로고    scopus 로고
    • Bcl-2 expression correlates with apoptosis induction but not loss of clonogenic survival in small cell lung cancer cell lines treated with etoposide
    • C. Breton, M.D. Story, R.E. Meyn Bcl-2 expression correlates with apoptosis induction but not loss of clonogenic survival in small cell lung cancer cell lines treated with etoposide Anticancer Drugs 9 1998 751 757
    • (1998) Anticancer Drugs , vol.9 , pp. 751-757
    • Breton, C.1    Story, M.D.2    Meyn, R.E.3
  • 76
    • 0000607643 scopus 로고    scopus 로고
    • Radiation-induced apoptosis and its relationship to loss of clonogenic survival
    • K.D. Held Radiation-induced apoptosis and its relationship to loss of clonogenic survival Apoptosis 2 1997 265 282
    • (1997) Apoptosis , vol.2 , pp. 265-282
    • Held, K.D.1
  • 77
    • 0242329764 scopus 로고    scopus 로고
    • Bcl-x(L) antisense oligonucleotides radiosensitise colon cancer cells
    • V. Wacheck, E. Selzer, P. Gunsberg Bcl-x(L) antisense oligonucleotides radiosensitise colon cancer cells Br J Cancer 89 2003 1352 1357
    • (2003) Br J Cancer , vol.89 , pp. 1352-1357
    • Wacheck, V.1    Selzer, E.2    Gunsberg, P.3
  • 78
    • 22944436158 scopus 로고    scopus 로고
    • Mcl-1 blocks radiation-induced apoptosis and clonogenic cell death
    • H. Skvara, C. Thallinger, V. Wacheck Mcl-1 blocks radiation-induced apoptosis and clonogenic cell death Anticancer Res 25 2005 2697 2703
    • (2005) Anticancer Res , vol.25 , pp. 2697-2703
    • Skvara, H.1    Thallinger, C.2    Wacheck, V.3
  • 79
    • 3042570258 scopus 로고    scopus 로고
    • Mcl-1 is a novel therapeutic target for human sarcoma: Synergistic inhibition of human sarcoma xerotransplants by a combination of mcl-1 antisense oligonucleotides with low dose cyclophosphamide
    • C. Thallinger, M.F. Wolschek, H. Maierhofer Mcl-1 is a novel therapeutic target for human sarcoma Synergistic inhibition of human sarcoma xerotransplants by a combination of mcl-1 antisense oligonucleotides with low dose cyclophosphamide Clin Cancer Res 10 2004 4185 4191
    • (2004) Clin Cancer Res , vol.10 , pp. 4185-4191
    • Thallinger, C.1    Wolschek, M.F.2    Maierhofer, H.3
  • 80
    • 0034684471 scopus 로고    scopus 로고
    • Chemosensitization of malignant melanoma by bcl2 antisense therapy
    • B. Jansen, V. Wacheck, E. Heere-Ress Chemosensitization of malignant melanoma by bcl2 antisense therapy Lancet 356 2000 1728 1733
    • (2000) Lancet , vol.356 , pp. 1728-1733
    • Jansen, B.1    Wacheck, V.2    Heere-Ress, E.3
  • 81
    • 0031907428 scopus 로고    scopus 로고
    • Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
    • B. Jansen, H. Schlagbayer-Wadl, B.D. Brown Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice Nat Med 1998 4232 4234
    • (1998) Nat Med , pp. 4232-4234
    • Jansen, B.1    Schlagbayer-Wadl, H.2    Brown, B.D.3
  • 82
    • 0032580348 scopus 로고    scopus 로고
    • Human gene therapy
    • W.F. Anderson Human gene therapy Nature 392 1998 25 30
    • (1998) Nature , vol.392 , pp. 25-30
    • Anderson, W.F.1
  • 83
    • 0030631615 scopus 로고    scopus 로고
    • Gene therapy approaches to enhance antitumor immunity
    • D.L. Shawler, H. Fakhrai, C. Van Beveren Gene therapy approaches to enhance antitumor immunity Adv Pharmacol 40 1997 309 337
    • (1997) Adv Pharmacol , vol.40 , pp. 309-337
    • Shawler, D.L.1    Fakhrai, H.2    Van Beveren, C.3
  • 84
    • 85047696411 scopus 로고    scopus 로고
    • Local tumor irradiation augments the anti-tumor effect of cytokine producing autologous cancer cell vaccines in a murine glioma model
    • K. Lumniczky, S.Z. Désaknai, L. Mangel Local tumor irradiation augments the anti-tumor effect of cytokine producing autologous cancer cell vaccines in a murine glioma model Cancer Gene Ther 9 2002 44 52
    • (2002) Cancer Gene Ther , vol.9 , pp. 44-52
    • Lumniczky, K.1    Désaknai, S.Z.2    Mangel, L.3
  • 85
    • 1542781699 scopus 로고    scopus 로고
    • Local tumor irradiation enhances the anti-tumor effect of a double-suicide gene therapy system in a murine glioma model
    • S.Z. Desaknai, K. Lumniczky, O. Esik Local tumor irradiation enhances the anti-tumor effect of a double-suicide gene therapy system in a murine glioma model J Gene Med 5 2003 377 385
    • (2003) J Gene Med , vol.5 , pp. 377-385
    • Desaknai, S.Z.1    Lumniczky, K.2    Esik, O.3
  • 86
    • 0036023450 scopus 로고    scopus 로고
    • Role of deoxycytidine kinase (dCK) activity in gemcitabine's radioenhancement in mice and human cell lines in vitro
    • V. Gregoire, J.F. Rosier, M. De Bast Role of deoxycytidine kinase (dCK) activity in gemcitabine's radioenhancement in mice and human cell lines in vitro Radiother Oncol 63 2002 329 338
    • (2002) Radiother Oncol , vol.63 , pp. 329-338
    • Gregoire, V.1    Rosier, J.F.2    De Bast, M.3
  • 87
    • 0028141973 scopus 로고
    • Radiation induction of immediate early genes: Effectors of the radiation stress response
    • R.R. Weichselbaum, D.E. Hallahan, Z. Fuks Radiation induction of immediate early genes Effectors of the radiation stress response Int J Radiat Oncol Biol Phys 30 1994 229 234
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , pp. 229-234
    • Weichselbaum, R.R.1    Hallahan, D.E.2    Fuks, Z.3
  • 88
    • 0027963649 scopus 로고
    • Gene therapy targeted by radiation preferentially radiosensitizes tumor cells
    • R.R. Weichselbaum, D.E. Hallahan, M.A. Beckett Gene therapy targeted by radiation preferentially radiosensitizes tumor cells Cancer Res 54 1994 4266 4269
    • (1994) Cancer Res , vol.54 , pp. 4266-4269
    • Weichselbaum, R.R.1    Hallahan, D.E.2    Beckett, M.A.3
  • 90
    • 0029159918 scopus 로고
    • Spatial and temporal control of gene therapy using ionizing radiation
    • D.E. Hallahan, H.J. Mauceri, L.P. Seung Spatial and temporal control of gene therapy using ionizing radiation Nat Med 1 1995 786 791
    • (1995) Nat Med , vol.1 , pp. 786-791
    • Hallahan, D.E.1    Mauceri, H.J.2    Seung, L.P.3
  • 91
    • 0029559345 scopus 로고
    • Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to gancyclovir
    • T. Joki, M. Nakamura, T. Ohno Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to gancyclovir Hum Gene Ther 6 1995 1507 1513
    • (1995) Hum Gene Ther , vol.6 , pp. 1507-1513
    • Joki, T.1    Nakamura, M.2    Ohno, T.3
  • 92
    • 0030919225 scopus 로고    scopus 로고
    • Induction of the suicide HSV TK gene by activation of the EGR 1 promoter with radioisotopes
    • T. Takahashi, Y. Namiki, T. Ohno Induction of the suicide HSV TK gene by activation of the EGR 1 promoter with radioisotopes Hum Gene Ther 8 1997 827 833
    • (1997) Hum Gene Ther , vol.8 , pp. 827-833
    • Takahashi, T.1    Namiki, Y.2    Ohno, T.3
  • 93
    • 0026452858 scopus 로고
    • Ionizing radiation activates transcription of the EGR1 gene via CArG elements
    • R. Datta, E. Rubin, V. Sukhatme Ionizing radiation activates transcription of the EGR1 gene via CArG elements Proc Natl Acad Sci USA 89 1992 10149 10153
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10149-10153
    • Datta, R.1    Rubin, E.2    Sukhatme, V.3
  • 94
    • 0027512020 scopus 로고
    • 6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation
    • 6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation Proc Natl Acad Sci USA 90 1993 2419 2422
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2419-2422
    • Datta, R.1    Taneja, N.2    Sukhatme, V.P.3
  • 95
    • 0032126019 scopus 로고    scopus 로고
    • Transgene expression in malignant glioma using a replication-defective adenoviral vector containing the EGR-1 promoter: Activation by ionizing radiation or uptake of radioactive iodo-deoxyuridine
    • Y. Manome, T. Kunieda, P.Y. Wen Transgene expression in malignant glioma using a replication-defective adenoviral vector containing the EGR-1 promoter Activation by ionizing radiation or uptake of radioactive iodo-deoxyuridine Hum Gene Ther 9 1998 1409 1417
    • (1998) Hum Gene Ther , vol.9 , pp. 1409-1417
    • Manome, Y.1    Kunieda, T.2    Wen, P.Y.3
  • 96
    • 0036845222 scopus 로고    scopus 로고
    • Radiation-induced tumour necrosis factor-α expression: Clinical application of transcriptional and physical targeting of gene therapy
    • R.R. Weichselbaum, D.W. Kufe, S. Hellman Radiation-induced tumour necrosis factor-α expression Clinical application of transcriptional and physical targeting of gene therapy Lancet Oncol 3 2002 665 671
    • (2002) Lancet Oncol , vol.3 , pp. 665-671
    • Weichselbaum, R.R.1    Kufe, D.W.2    Hellman, S.3
  • 97
    • 0034062266 scopus 로고    scopus 로고
    • Development of synthetic promoters for radiation-mediated gene therapy
    • B. Marples, S.D. Scott, J.H. Hendry Development of synthetic promoters for radiation-mediated gene therapy Gene Ther 7 2000 511 517
    • (2000) Gene Ther , vol.7 , pp. 511-517
    • Marples, B.1    Scott, S.D.2    Hendry, J.H.3
  • 98
    • 0033925131 scopus 로고    scopus 로고
    • A radiation-controlled molecular switch for use in gene therapy of cancer
    • S.D. Scott, B. Marples, J.H. Hendry A radiation-controlled molecular switch for use in gene therapy of cancer Gene Ther 7 2000 1121 1125
    • (2000) Gene Ther , vol.7 , pp. 1121-1125
    • Scott, S.D.1    Marples, B.2    Hendry, J.H.3
  • 99
    • 0029986585 scopus 로고    scopus 로고
    • Tissue specific promoters in targeting systemically delivered gene therapy
    • I.R. Hart Tissue specific promoters in targeting systemically delivered gene therapy Semin Oncol 23 1996 154 158
    • (1996) Semin Oncol , vol.23 , pp. 154-158
    • Hart, I.R.1
  • 100
    • 0035312501 scopus 로고    scopus 로고
    • Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells
    • S.J. Collis, A. Tighe, S.D. Scott Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells Nucleic Acids Res 29 2001 1534 1538
    • (2001) Nucleic Acids Res , vol.29 , pp. 1534-1538
    • Collis, S.J.1    Tighe, A.2    Scott, S.D.3
  • 101
    • 0038347805 scopus 로고    scopus 로고
    • Transcriptional targeting in cancer gene therapy
    • T. Robson, D.G. Hirst Transcriptional targeting in cancer gene therapy J Biomed Biotechnol 2003 2003 110 137
    • (2003) J Biomed Biotechnol , vol.2003 , pp. 110-137
    • Robson, T.1    Hirst, D.G.2
  • 102
    • 0036328116 scopus 로고    scopus 로고
    • Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours
    • A.V. Patterson, K.J. Williams, R.L. Cowen Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours Gene Ther 9 2002 946 954
    • (2002) Gene Ther , vol.9 , pp. 946-954
    • Patterson, A.V.1    Williams, K.J.2    Cowen, R.L.3


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