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Volumn 49, Issue 2, 2001, Pages 319-326

Therapeutic targets in radiotherapy

Author keywords

C 225; Cisplatin; Epidermal growth factor receptors; Farnesyltransferase inhibitors; Ras; Tirapazamine; Tumor hypoxia

Indexed keywords

2 [[2 [[2 [(2 AMINO 3 MERCAPTOPROPYL)AMINO] 3 METHYLPENTYL]OXY] 1 OXO 3 PHENYLPROPYL]AMINO] 4 (METHYLSULFONYL)BUTANOIC ACID ISOPROPYL ESTER; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GGTI 298; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PROTEIN FARNESYLTRANSFERASE INHIBITOR; TIRAPAZAMINE;

EID: 0035254642     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(00)01482-6     Document Type: Conference Paper
Times cited : (70)

References (50)
  • 2
    • 0027473872 scopus 로고
    • Increased radioresistance of EJras-transformed human osteosarcoma cells and its modulation by lovastatin, an inhibitor of p21ras isoprenylation
    • (1993) Int J Cancer , vol.53 , pp. 302-307
    • Miller, A.C.1    Kariko, K.2    Myers, C.E.3
  • 4
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer; A review
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 17
    • 0027428571 scopus 로고
    • Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts
    • (1993) Cancer Res , vol.53 , pp. 4637-4642
    • Fan, Z.1    Baselga, J.2    Masui, H.3
  • 21
    • 0032815618 scopus 로고    scopus 로고
    • Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
    • (1999) Mol Biol Cell , vol.10 , pp. 2493-2506
    • Dent, P.1    Reardon, D.B.2    Park, J.S.3
  • 22
    • 0021254542 scopus 로고
    • Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity
    • (1984) J Biol Chem , vol.259 , pp. 7755-7760
    • Gill, G.N.1    Kawamoto, T.2    Cochet, C.3
  • 23
    • 0031409362 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy
    • (1997) Clin Cancer Res , vol.3 , pp. 2703-2707
    • Mendelsohn, J.1
  • 25
    • 0033561522 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
    • (1999) Cancer Res , vol.59 , pp. 1935-1940
    • Huang, S.M.1    Bock, J.M.2    Harari, P.M.3
  • 26
  • 27
    • 0030757686 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor gene expression and function decreases proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells
    • (1997) Oncogene , vol.15 , pp. 409-416
    • Rubin Grandis, J.1    Chakraborty, A.2    Melhem, M.F.3
  • 29
    • 0025807618 scopus 로고
    • Oxygenation of human tumors; evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements
    • (1991) Cancer Res , vol.51 , pp. 3316-3322
    • Vaupel, P.1    Schlenger, K.2    Knoop, C.3
  • 32
    • 0030926491 scopus 로고    scopus 로고
    • Cells at intermediate oxygen levels can be more important than the 'hypoxic fraction' in determining tumor response to fractionated radiotherapy
    • (1997) Radiat Res , vol.147 , pp. 541-550
    • Wouters, B.G.1    Brown, J.M.2
  • 44
    • 0025646401 scopus 로고
    • Potentiation by the hypoxic cytotoxin SR 4233 of cell killing produced by fractionated irradiation of mouse tumors
    • (1990) Cancer Res , vol.50 , pp. 7745-7749
    • Brown, J.M.1    Lemmon, M.J.2
  • 45
    • 84965808588 scopus 로고
    • Tumor-specific, schedule-dependent interaction between tirapazamine (SR 4233) and cisplatin
    • (1993) Cancer Res , vol.53 , pp. 4633-4636
    • Dorie, M.J.1    Brown, J.M.2
  • 47
    • 0027220811 scopus 로고
    • Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents; A new class of bioreductive agent
    • (1993) Cancer Metastasis Rev , vol.12 , pp. 119-134
    • Patterson, L.H.1
  • 50
    • 0034084314 scopus 로고    scopus 로고
    • Modulation of radiation response following epidermal growth factor receptor blockade in squamous cell carcinomas; Inhibition of damage repair, cell cycle kinetics and tumor angiogenesis
    • (2000) Clin Cancer Res , vol.6 , pp. 2166-2174
    • Huang, S.M.1    Harari, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.