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Volumn 63, Issue SUPPL. 2, 2002, Pages 19-28

Raising hemoglobin: An opportunity for increasing survival?

Author keywords

Anemia; Angiogenesis; Cancer; Chemotherapy; Epoetin alfa; Hemoglobin; Hypoxia; Prognostic factor; Radiotherapy; Surgery

Indexed keywords

HEMOGLOBIN; OXYGEN;

EID: 0036906874     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000067148     Document Type: Review
Times cited : (31)

References (42)
  • 1
    • 0035514836 scopus 로고    scopus 로고
    • Anemia treatment and the radiation oncologist: Optimizing patient outcomes
    • Shasha D, Harrison LB: Anemia treatment and the radiation oncologist: Optimizing patient outcomes. Oncology (Huntingt) 2001;15:1486-1496.
    • (2001) Oncology (Huntingt) , vol.15 , pp. 1486-1496
    • Shasha, D.1    Harrison, L.B.2
  • 2
    • 0034989312 scopus 로고    scopus 로고
    • The impact of hemoglobin levels on treatment outcomes in patients with cancer
    • Littlewood TJ: The impact of hemoglobin levels on treatment outcomes in patients with cancer. Semin Oncol 2001;26(suppl 8):49-53.
    • (2001) Semin Oncol , vol.26 , Issue.SUPPL. 8 , pp. 49-53
    • Littlewood, T.J.1
  • 3
    • 0023262969 scopus 로고
    • Radiation therapy and the role of red blood cell transfusion
    • Poskitt TR: Radiation therapy and the role of red blood cell transfusion. Cancer Invest 1987; 5:231-236.
    • (1987) Cancer Invest , vol.5 , pp. 231-236
    • Poskitt, T.R.1
  • 6
    • 0033560677 scopus 로고    scopus 로고
    • Improved treatment for cervical cancer - Concurrent chemotherapy and radiotherapy
    • Thomas GM: Improved treatment for cervical cancer - Concurrent chemotherapy and radiotherapy. N Eng J Med 1999;340:1198-1200.
    • (1999) N Eng J Med , vol.340 , pp. 1198-1200
    • Thomas, G.M.1
  • 7
    • 0037083482 scopus 로고    scopus 로고
    • Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix
    • Pearcey RG, Brundage M, Drouin P, Jeffrey J, Johnston D, Lukka H, MacLean G, Souhami L, Stuart G, Tu D: Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix. J Clin Oncology 2002;20:966-972.
    • (2002) J Clin Oncology , vol.20 , pp. 966-972
    • Pearcey, R.G.1    Brundage, M.2    Drouin, P.3    Jeffrey, J.4    Johnston, D.5    Lukka, H.6    MacLean, G.7    Souhami, L.8    Stuart, G.9    Tu, D.10
  • 8
    • 0032895783 scopus 로고    scopus 로고
    • Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: A Gynecologic Oncology Group and Southwest Oncology Group study
    • Whitney CW, Sause W, Bundy BN, Malfetano JH, Hannigan EV, Fowler WC, Clarke-Pearson DL, Liao SY: Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: A Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol 1999;17:1339-1348.
    • (1999) J Clin Oncol , vol.17 , pp. 1339-1348
    • Whitney, C.W.1    Sause, W.2    Bundy, B.N.3    Malfetano, J.H.4    Hannigan, E.V.5    Fowler, W.C.6    Clarke-Pearson, D.L.7    Liao, S.Y.8
  • 11
    • 0033561259 scopus 로고    scopus 로고
    • Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma
    • Keys HM, Bundy BN, Stehman FB, Muderspach LI, Chafe WE, Suggs CL, Walker JL, Gersell D: Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Eng J Med 1999;340:1154-1161.
    • (1999) N Eng J Med , vol.340 , pp. 1154-1161
    • Keys, H.M.1    Bundy, B.N.2    Stehman, F.B.3    Muderspach, L.I.4    Chafe, W.E.5    Suggs, C.L.6    Walker, J.L.7    Gersell, D.8
  • 12
    • 0033993937 scopus 로고    scopus 로고
    • Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix
    • Peters WA, Liu PY, Barrett RJ, Stock RJ, Monk BJ, Souhami L, Grigsby P, Gordon W, Alberts DS: Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol 2000;18:1606-1613.
    • (2000) J Clin Oncol , vol.18 , pp. 1606-1613
    • Peters, W.A.1    Liu, P.Y.2    Barrett, R.J.3    Stock, R.J.4    Monk, B.J.5    Souhami, L.6    Grigsby, P.7    Gordon, W.8    Alberts, D.S.9
  • 13
    • 0034046859 scopus 로고    scopus 로고
    • Impact of anemia in patients with head and neck cancer
    • Kumar P: Impact of anemia in patients with head and neck cancer. Oncologist 2000;5(suppl 2):13-18.
    • (2000) Oncologist , vol.5 , Issue.SUPPL. 2 , pp. 13-18
    • Kumar, P.1
  • 14
    • 0026608117 scopus 로고
    • The prognostic value of hemoglobin and a decrease in hemoglobin during radiotherapy in laryngeal carcinoma
    • van Acht MJ, Hermans J, Boks DE, Leer JW: The prognostic value of hemoglobin and a decrease in hemoglobin during radiotherapy in laryngeal carcinoma. Radiother Oncol 1992;23:229-235.
    • (1992) Radiother Oncol , vol.23 , pp. 229-235
    • Van Acht, M.J.1    Hermans, J.2    Boks, D.E.3    Leer, J.W.4
  • 15
    • 0034743861 scopus 로고    scopus 로고
    • Oxygenation status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
    • Vaupel P, Kelleher DK, Höckel M: Oxygenation status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 2001;2(suppl 8):29-35.
    • (2001) Semin Oncol , vol.2 , Issue.SUPPL. 8 , pp. 29-35
    • Vaupel, P.1    Kelleher, D.K.2    Höckel, M.3
  • 17
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Höckel M, Schlenger K, Aral B, Mitze M, Schäffer U, Vaupel P: Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996;56:4509-4515.
    • (1996) Cancer Res , vol.56 , pp. 4509-4515
    • Höckel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schäffer, U.5    Vaupel, P.6
  • 18
    • 0014389382 scopus 로고
    • Intercapillary distance, oxygen tension and local recurrence in cervix cancer
    • Kolstad P: Intercapillary distance, oxygen tension and local recurrence in cervix cancer. Scand J Clin Lab Invest 1968;106(suppl):145-157.
    • (1968) Scand J Clin Lab Invest , vol.106 , Issue.SUPPL. , pp. 145-157
    • Kolstad, P.1
  • 21
    • 0029955072 scopus 로고    scopus 로고
    • Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
    • Nordsmark M, Overgaard M, Overgaard J: Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 1996;41:31-39.
    • (1996) Radiother Oncol , vol.41 , pp. 31-39
    • Nordsmark, M.1    Overgaard, M.2    Overgaard, J.3
  • 22
    • 0034989311 scopus 로고    scopus 로고
    • Biological consequences of tumor hypoxia
    • Höckel M, Vaupel P: Biological consequences of tumor hypoxia. Semin Oncol 2001;28(suppl 8):36-41.
    • (2001) Semin Oncol , vol.28 , Issue.SUPPL. 8 , pp. 36-41
    • Höckel, M.1    Vaupel, P.2
  • 23
    • 0027960791 scopus 로고
    • Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression
    • Hlatky L, Tsionou C, Hahnfeldt P, Coleman CN: Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression. Cancer Res 1994;54:6083-6086.
    • (1994) Cancer Res , vol.54 , pp. 6083-6086
    • Hlatky, L.1    Tsionou, C.2    Hahnfeldt, P.3    Coleman, C.N.4
  • 24
    • 0027768808 scopus 로고
    • Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas
    • Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Dvorak HF, Senger DR: Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas. Am J Pathol 1993;143:1255-1262.
    • (1993) Am J Pathol , vol.143 , pp. 1255-1262
    • Brown, L.F.1    Berse, B.2    Jackman, R.W.3    Tognazzi, K.4    Manseau, E.J.5    Dvorak, H.F.6    Senger, D.R.7
  • 25
    • 0031823016 scopus 로고    scopus 로고
    • The molecular basis of the hypoxia response pathway: Tumour hypoxia as a therapy target
    • Blancher C, Harris AL: The molecular basis of the hypoxia response pathway: Tumour hypoxia as a therapy target. Cancer Metastasis Rev 1998;17(2):187-194.
    • (1998) Cancer Metastasis Rev , vol.17 , Issue.2 , pp. 187-194
    • Blancher, C.1    Harris, A.L.2
  • 27
    • 0034282518 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
    • Birner P, Schindl M, Obermair A, Plank C, Breitenecker G, Oberhuber G: Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res 2000;60:4693-4696.
    • (2000) Cancer Res , vol.60 , pp. 4693-4696
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Plank, C.4    Breitenecker, G.5    Oberhuber, G.6
  • 28
    • 0012146302 scopus 로고    scopus 로고
    • Hypoxia and hemoglobin as prognostic markers of survival in head & neck carcinoma after primary radiation therapy. An international multi-center study
    • abstract 125
    • Nordsmark M, Rudat V, Lartigau E, Stadler P, Becker A, Adam M, Molls M, Dunst J, Terris D, Overgaard J: Hypoxia and hemoglobin as prognostic markers of survival in head & neck carcinoma after primary radiation therapy. An international multi-center study (abstract 125). Eur J Cancer 2001;37(suppl 6):37.
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 6 , pp. 37
    • Nordsmark, M.1    Rudat, V.2    Lartigau, E.3    Stadler, P.4    Becker, A.5    Adam, M.6    Molls, M.7    Dunst, J.8    Terris, D.9    Overgaard, J.10
  • 29
    • 0032708195 scopus 로고    scopus 로고
    • Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
    • Brizel DM, Dodge RK, Clough RW, Dewhirst MW: Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome. Radiother Oncol 1999;53:113-117.
    • (1999) Radiother Oncol , vol.53 , pp. 113-117
    • Brizel, D.M.1    Dodge, R.K.2    Clough, R.W.3    Dewhirst, M.W.4
  • 30
    • 0032977983 scopus 로고    scopus 로고
    • Low hemoglobin is associated with increased serum levels of vascular endothelial growth factor (VEGF) in cancer patients. Does anemia stimulate angiogenesis?
    • Dunst J, Pigorsch S, Hansgen G, Hintner I, Lautenschlager C, Becker A: Low hemoglobin is associated with increased serum levels of vascular endothelial growth factor (VEGF) in cancer patients. Does anemia stimulate angiogenesis? Strahlenther Onkol 1999;175:93-96.
    • (1999) Strahlenther Onkol , vol.175 , pp. 93-96
    • Dunst, J.1    Pigorsch, S.2    Hansgen, G.3    Hintner, I.4    Lautenschlager, C.5    Becker, A.6
  • 31
    • 0035367087 scopus 로고    scopus 로고
    • Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: Results of a randomized, double-blind, placebo-controlled trial
    • Littlewood TJ, Bajetta E, Nortier JWR, Vercammen E, Rapoport B: Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: Results of a randomized, double-blind, placebo-controlled trial. J Clin Oncol 2001;19:2865-2874.
    • (2001) J Clin Oncol , vol.19 , pp. 2865-2874
    • Littlewood, T.J.1    Bajetta, E.2    Nortier, J.W.R.3    Vercammen, E.4    Rapoport, B.5
  • 33
    • 0028803524 scopus 로고
    • Epoetin alfa for the treatment of the anemia of multiple myeloma. A prospective, randomized, placebo-controlled, double-blind trial
    • Garton JP, Gertz MA, Witzig TE, Greipp PR, Lust JA, Schroeder G, Kyle RA: Epoetin alfa for the treatment of the anemia of multiple myeloma. A prospective, randomized, placebo-controlled, double-blind trial. Arch Intern Med 1995;155:2069-2074.
    • (1995) Arch Intern Med , vol.155 , pp. 2069-2074
    • Garton, J.P.1    Gertz, M.A.2    Witzig, T.E.3    Greipp, P.R.4    Lust, J.A.5    Schroeder, G.6    Kyle, R.A.7
  • 34
    • 0031785826 scopus 로고    scopus 로고
    • Quality-of-life benefit in chemotherapy patients treated with epoetin alfa is independent of disease response or tumor type: Results from a prospective community oncology study
    • Demetri GD, Kris J, Wade J, Degas L, Celia D: Quality-of-life benefit in chemotherapy patients treated with epoetin alfa is independent of disease response or tumor type: Results from a prospective community oncology study. J Clin Oncol 1998;16:3412-3425.
    • (1998) J Clin Oncol , vol.16 , pp. 3412-3425
    • Demetri, G.D.1    Kris, J.2    Wade, J.3    Degas, L.4    Celia, D.5
  • 35
    • 0031044609 scopus 로고    scopus 로고
    • Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice
    • Glaspy J, Bukowski R, Steinberg D, Taylor C, Tchekmedyian S, Vadhan-Raj S: Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice. J Clin Oncol 1997;15:1218-1234.
    • (1997) J Clin Oncol , vol.15 , pp. 1218-1234
    • Glaspy, J.1    Bukowski, R.2    Steinberg, D.3    Taylor, C.4    Tchekmedyian, S.5    Vadhan-Raj, S.6
  • 36
    • 0031729893 scopus 로고    scopus 로고
    • Clinical trial experience using erythropoietin during radiation therapy
    • Lavey RS: Clinical trial experience using erythropoietin during radiation therapy. Strahlenther Onkol 1998;174(suppl 4):24-30.
    • (1998) Strahlenther Onkol , vol.174 , Issue.SUPPL. 4 , pp. 24-30
    • Lavey, R.S.1
  • 37
    • 0028025601 scopus 로고
    • Erythropoietin increases hemoglobin during radiation therapy for cervical cancer
    • Dusenbery KE, McGuire WA, Holt PJ, et al: Erythropoietin increases hemoglobin during radiation therapy for cervical cancer. Int J Radiat Oncol Biol Phys 1994;29:1079-1084.
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , pp. 1079-1084
    • Dusenbery, K.E.1    McGuire, W.A.2    Holt, P.J.3
  • 38
    • 0001053367 scopus 로고    scopus 로고
    • Effect of the administration of recombinant human erythropoietin in patients with pelvic malignancies during radiotherapy
    • Antonadou D, Cardamakis E, Sarris G, et al: Effect of the administration of recombinant human erythropoietin in patients with pelvic malignancies during radiotherapy. Radiother Onol 1998;48:S122.
    • (1998) Radiother Onol , vol.48
    • Antonadou, D.1    Cardamakis, E.2    Sarris, G.3
  • 39
    • 0035400246 scopus 로고    scopus 로고
    • Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx
    • Glaser CM, Millesi W, Kornek GV, Lang S, Schull B, Watzinger F, Selzer E, Lavey RS: Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx. Int J Radiat Oncol Biol Phys 2001;50(3):705-715.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , Issue.3 , pp. 705-715
    • Glaser, C.M.1    Millesi, W.2    Kornek, G.V.3    Lang, S.4    Schull, B.5    Watzinger, F.6    Selzer, E.7    Lavey, R.S.8
  • 40
    • 26144447382 scopus 로고    scopus 로고
    • The effect of systematic rHu-erythropoietin (Epoietin alpha [sic]) treatment before and during radiotherapy (radio-chemotherapy) in unselected anemic cancer patients: Results of an Austrian multi-center observation study
    • abstract 1465
    • Hawliczek R, Oismüller R: The effect of systematic rHu-erythropoietin (Epoietin alpha [sic]) treatment before and during radiotherapy (radio-chemotherapy) in unselected anemic cancer patients: Results of an Austrian multi-center observation study (abstract 1465). Eur J Cancer Clin Oncol 1999;35(suppl 4):S361.
    • (1999) Eur J Cancer Clin Oncol , vol.35 , Issue.SUPPL. 4
    • Hawliczek, R.1    Oismüller, R.2
  • 41
    • 0035366382 scopus 로고    scopus 로고
    • Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: Improvements in hemoglobin and quality of life are similar to three-times-weekly dosing
    • Gabrilove JL, Cleeland CS, Livingston RB, Sarokhan B, Winer E, Einhorn LH: Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: Improvements in hemoglobin and quality of life are similar to three-times-weekly dosing. J Clin Oncol 2001;19:2875-2882.
    • (2001) J Clin Oncol , vol.19 , pp. 2875-2882
    • Gabrilove, J.L.1    Cleeland, C.S.2    Livingston, R.B.3    Sarokhan, B.4    Winer, E.5    Einhorn, L.H.6


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