Insulin increases the sensitivity of tumors to irradiation: Involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption

Cancer Research

Volumn 62, Issue 12, 2002, Pages 3555-3561

  Jordan, Bénédicte F ^a   Grégoire, Vincent ^a   Demeure, Roger J ^a   Sonveaux, Pierre ^c   Feron, Olivier ^c   O'Hara, Julia ^c   Vanhulle, Valérie P ^c   Delzenne, Nathalie ^c   Gallez, Bernard ^a,c  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; INSULIN; N(G) NITROARGININE METHYL ESTER; NEUTRAL INSULIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME PHOSPHORYLATION; FIBER OPTICS; FIBROSARCOMA; IMMUNOBLOTTING; IN VIVO STUDY; INSULIN INFUSION; INSULIN RELEASE; LASER DOPPLER FLOWMETRY; LIVER TUMOR; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN CONSUMPTION; OXYGENATION; PERFUSION; PRIORITY JOURNAL; RADIATION DOSE; RADIOSENSITIVITY; TUMOR BLOOD FLOW; TUMOR MODEL;

ANIMALS; CYCLIC GMP; ENERGY METABOLISM; FIBROSARCOMA; INSULIN; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C3H; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXYGEN; OXYGEN CONSUMPTION; PARTIAL PRESSURE; PHOSPHORYLATION; RADIATION-SENSITIZING AGENTS;

EID: 0037096740     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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