메뉴 건너뛰기




Volumn 20, Issue 1, 2006, Pages 119-139

Radiation modifiers: Treatment overview and future investigations

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 AMINOPROPYLAMINO)ETHANETHIOL; AMIFOSTINE; ASCORBIC ACID; CAPECITABINE; CARBOPLATIN; CISPLATIN; CYCLOOXYGENASE 2 INHIBITOR; DNA TOPOISOMERASE INHIBITOR; DOCETAXEL; ETANIDAZOLE; FLUOROPYRIMIDINE; FLUOROURACIL; GEMCITABINE; IRINOTECAN; MEVINOLIN; MISONIDAZOLE; NIMORAZOLE; OXALIPLATIN; PACLITAXEL; PENTOXIFYLLINE; PILOCARPINE; SUCRALFATE; TIRAPAZAMINE; TOCOPHEROL;

EID: 33645416090     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hoc.2006.01.012     Document Type: Review
Times cited : (9)

References (224)
  • 3
    • 0023667703 scopus 로고
    • Kinetics and thermodynamics of the interaction of 5-fluoro-2′- deoxyuridylate with thymidylate synthase
    • D.V. Santi, C.S. McHenry, and R.T. Raines Kinetics and thermodynamics of the interaction of 5-fluoro-2′-deoxyuridylate with thymidylate synthase Biochemistry 26 1987 8606 8613
    • (1987) Biochemistry , vol.26 , pp. 8606-8613
    • Santi, D.V.1    McHenry, C.S.2    Raines, R.T.3
  • 4
    • 0344109583 scopus 로고    scopus 로고
    • Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. Meta-analysis Group in Cancer
    • Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. Meta-analysis Group In Cancer J Clin Oncol 16 1998 301 308
    • (1998) J Clin Oncol , vol.16 , pp. 301-308
  • 5
    • 0345596364 scopus 로고    scopus 로고
    • Toxicity of fluorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors. Meta-Analysis Group in Cancer
    • Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors. Meta-Analysis Group In Cancer J Clin Oncol 16 1998 3537 3541
    • (1998) J Clin Oncol , vol.16 , pp. 3537-3541
  • 6
    • 0034798771 scopus 로고    scopus 로고
    • The evolution of fluoropyrimidine therapy: From intravenous to oral
    • P.M. Hoff, J. Cassidy, and H.J. Schmoll The evolution of fluoropyrimidine therapy: from intravenous to oral Oncologist 6 Suppl 4 2001 3 11
    • (2001) Oncologist , vol.6 , Issue.SUPPL. 4 , pp. 3-11
    • Hoff, P.M.1    Cassidy, J.2    Schmoll, H.J.3
  • 7
    • 0031017851 scopus 로고    scopus 로고
    • Patient preferences for oral versus intravenous palliative chemotherapy
    • G. Liu, E. Franssen, and M.I. Fitch Patient preferences for oral versus intravenous palliative chemotherapy J Clin Oncol 15 1997 110 115
    • (1997) J Clin Oncol , vol.15 , pp. 110-115
    • Liu, G.1    Franssen, E.2    Fitch, M.I.3
  • 8
    • 0034791938 scopus 로고    scopus 로고
    • Answering patients' needs: Oral alternatives to intravenous therapy
    • M. Borner, W. Scheithauer, and C. Twelves Answering patients' needs: oral alternatives to intravenous therapy Oncologist 6 Suppl 4 2001 12 16
    • (2001) Oncologist , vol.6 , Issue.SUPPL. 4 , pp. 12-16
    • Borner, M.1    Scheithauer, W.2    Twelves, C.3
  • 9
    • 0036159485 scopus 로고    scopus 로고
    • Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: A randomised crossover trial in advanced colorectal cancer
    • M.M. Borner, P. Schoffski, and R. de Wit Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorin: a randomised crossover trial in advanced colorectal cancer Eur J Cancer 38 2002 349 358
    • (2002) Eur J Cancer , vol.38 , pp. 349-358
    • Borner, M.M.1    Schoffski, P.2    De Wit, R.3
  • 10
    • 0033564283 scopus 로고    scopus 로고
    • Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations
    • S. Marsh, E.S. Collie-Duguid, and T. Li Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations Genomics 58 1999 310 312
    • (1999) Genomics , vol.58 , pp. 310-312
    • Marsh, S.1    Collie-Duguid, E.S.2    Li, T.3
  • 11
    • 0035860142 scopus 로고    scopus 로고
    • A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil
    • B. Iacopetta, F. Grieu, and D. Joseph A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil Br J Cancer 85 2001 827 830
    • (2001) Br J Cancer , vol.85 , pp. 827-830
    • Iacopetta, B.1    Grieu, F.2    Joseph, D.3
  • 12
    • 0023680391 scopus 로고
    • Chemo/radiation with and without surgery in the thoracic esophagus: The Wayne State experience
    • A. Herskovic, L. Leichman, and P. Lattin Chemo/radiation with and without surgery in the thoracic esophagus: the Wayne State experience Int J Radiat Oncol Biol Phys 15 1988 655 662
    • (1988) Int J Radiat Oncol Biol Phys , vol.15 , pp. 655-662
    • Herskovic, A.1    Leichman, L.2    Lattin, P.3
  • 13
    • 0034796490 scopus 로고    scopus 로고
    • Concurrent chemoradiotherapy for squamous cell carcinoma of thoracic esophagus: Feasibility and outcome of large regional field and high-dose external beam boost irradiation
    • T. Toita, K. Ogawa, and G. Adachi Concurrent chemoradiotherapy for squamous cell carcinoma of thoracic esophagus: feasibility and outcome of large regional field and high-dose external beam boost irradiation Jpn J Clin Oncol 31 2001 375 381
    • (2001) Jpn J Clin Oncol , vol.31 , pp. 375-381
    • Toita, T.1    Ogawa, K.2    Adachi, G.3
  • 14
    • 0006642028 scopus 로고    scopus 로고
    • [Concurrent concentrated radio-chemotherapy of epidermoid cancer of the esophagus. Long-term results of a phase II national multicenter trial in 122 non-operable patients (FFCD 8803)]
    • J.F. Seitz, C. Milan, and M. Giovannini [Concurrent concentrated radio-chemotherapy of epidermoid cancer of the esophagus. Long-term results of a phase II national multicenter trial in 122 non-operable patients (FFCD 8803)] Gastroenterol Clin Biol 24 2000 201 210 [in French]
    • (2000) Gastroenterol Clin Biol , vol.24 , pp. 201-210
    • Seitz, J.F.1    Milan, C.2    Giovannini, M.3
  • 15
    • 0018840499 scopus 로고
    • Infusional 5-fluorouracil and X-ray therapy for non-resectable esophageal cancer
    • J.E. Byfield, R. Barone, and J. Mendelsohn Infusional 5-fluorouracil and X-ray therapy for non-resectable esophageal cancer Cancer 45 1980 703 708
    • (1980) Cancer , vol.45 , pp. 703-708
    • Byfield, J.E.1    Barone, R.2    Mendelsohn, J.3
  • 16
    • 0033982015 scopus 로고    scopus 로고
    • Thirty-four patients with carcinoma of the cervical esophagus treated with chemoradiation therapy
    • B.H. Burmeister, G. Dickie, and B.M. Smithers Thirty-four patients with carcinoma of the cervical esophagus treated with chemoradiation therapy Arch Otolaryngol Head Neck Surg 126 2000 205 208
    • (2000) Arch Otolaryngol Head Neck Surg , vol.126 , pp. 205-208
    • Burmeister, B.H.1    Dickie, G.2    Smithers, B.M.3
  • 17
    • 0028240260 scopus 로고
    • Chemoradiation: A superior alternative for the primary management of esophageal carcinoma
    • L.R. Coia Chemoradiation: a superior alternative for the primary management of esophageal carcinoma Semin Radiat Oncol 4 1994 157 164
    • (1994) Semin Radiat Oncol , vol.4 , pp. 157-164
    • Coia, L.R.1
  • 18
    • 0033564802 scopus 로고    scopus 로고
    • The evaluation and treatment of patients receiving radiation therapy for carcinoma of the esophagus: Results of the 1992-1994 Patterns of Care Study
    • L.R. Coia, B.D. Minsky, and M.J. John The evaluation and treatment of patients receiving radiation therapy for carcinoma of the esophagus: results of the 1992-1994 Patterns of Care Study Cancer 85 1999 2499 2505
    • (1999) Cancer , vol.85 , pp. 2499-2505
    • Coia, L.R.1    Minsky, B.D.2    John, M.J.3
  • 19
    • 0026769381 scopus 로고
    • Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus
    • A. Herskovic, K. Martz, and M. al-Sarraf Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus N Engl J Med 326 1992 1593 1598
    • (1992) N Engl J Med , vol.326 , pp. 1593-1598
    • Herskovic, A.1    Martz, K.2    Al-Sarraf, M.3
  • 20
    • 0032170161 scopus 로고    scopus 로고
    • Combined chemoradiotherapy vs. radiotherapy alone for early stage squamous cell carcinoma of the esophagus: A study of the Eastern Cooperative Oncology Group
    • T.J. Smith, L.M. Ryan, and H.O. Douglass Jr Combined chemoradiotherapy vs. radiotherapy alone for early stage squamous cell carcinoma of the esophagus: a study of the Eastern Cooperative Oncology Group Int J Radiat Oncol Biol Phys 42 1998 269 276
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 269-276
    • Smith, T.J.1    Ryan, L.M.2    Douglass Jr., H.O.3
  • 21
    • 0033526355 scopus 로고    scopus 로고
    • Chemoradiotherapy of locally advanced esophageal cancer: Long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group
    • J.S. Cooper, M.D. Guo, and A. Herskovic Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group JAMA 281 1999 1623 1627
    • (1999) JAMA , vol.281 , pp. 1623-1627
    • Cooper, J.S.1    Guo, M.D.2    Herskovic, A.3
  • 22
    • 9544252934 scopus 로고    scopus 로고
    • Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: Results of a phase III randomized intergroup study
    • M. Flam, M. John, and T.F. Pajak Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study J Clin Oncol 14 1996 2527 2539
    • (1996) J Clin Oncol , vol.14 , pp. 2527-2539
    • Flam, M.1    John, M.2    Pajak, T.F.3
  • 23
    • 0030818152 scopus 로고    scopus 로고
    • The role of radiation therapy with 5-fluorouracil in anal cancer
    • B.J. Cummings The role of radiation therapy with 5-fluorouracil in anal cancer Semin Radiat Oncol 7 1997 306 312
    • (1997) Semin Radiat Oncol , vol.7 , pp. 306-312
    • Cummings, B.J.1
  • 24
    • 0037439583 scopus 로고    scopus 로고
    • Response to preoperative chemoradiation increases the use of sphincter-preserving surgery in patients with locally advanced low rectal carcinoma
    • C.H. Crane, J.M. Skibber, and B.W. Feig Response to preoperative chemoradiation increases the use of sphincter-preserving surgery in patients with locally advanced low rectal carcinoma Cancer 97 2003 517 524
    • (2003) Cancer , vol.97 , pp. 517-524
    • Crane, C.H.1    Skibber, J.M.2    Feig, B.W.3
  • 25
    • 0030975222 scopus 로고    scopus 로고
    • Infusional chemoradiation for operable rectal cancer: Post-, pre-, or nonoperative management?
    • Rich T.A. Infusional chemoradiation for operable rectal cancer: post-, pre-, or nonoperative management? Oncology 1997;11:295-300, 305
    • (1997) Oncology , vol.11 , pp. 295-300
    • Rich, T.A.1
  • 26
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery
    • M.J. O'Connell, J.A. Martenson, and H.S. Wieand Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery N Engl J Med 331 1994 502 507
    • (1994) N Engl J Med , vol.331 , pp. 502-507
    • O'Connell, M.J.1    Martenson, J.A.2    Wieand, H.S.3
  • 27
    • 0021792174 scopus 로고
    • Prolongation of the disease-free interval in surgically treated rectal carcinoma. Gastrointestinal Tumor Study Group
    • Prolongation of the disease-free interval in surgically treated rectal carcinoma. Gastrointestinal Tumor Study Group N Engl J Med 312 1985 1465 1472
    • (1985) N Engl J Med , vol.312 , pp. 1465-1472
  • 28
    • 0026071185 scopus 로고
    • Effective surgical adjuvant therapy for high-risk rectal carcinoma
    • J.E. Krook, C.G. Moertel, and L.L. Gunderson Effective surgical adjuvant therapy for high-risk rectal carcinoma N Engl J Med 324 1991 709 715
    • (1991) N Engl J Med , vol.324 , pp. 709-715
    • Krook, J.E.1    Moertel, C.G.2    Gunderson, L.L.3
  • 29
    • 0029093508 scopus 로고
    • Preoperative infusional chemoradiation therapy for stage T3 rectal cancer
    • T.A. Rich, J.M. Skibber, and J.A. Ajani Preoperative infusional chemoradiation therapy for stage T3 rectal cancer Int J Radiat Oncol Biol Phys 32 1995 1025 1029
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 1025-1029
    • Rich, T.A.1    Skibber, J.M.2    Ajani, J.A.3
  • 30
    • 0017235503 scopus 로고
    • Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oral cavity and oropharynx: A randomized study
    • T.C. Lo, A.L. Wiley Jr, and F.J. Ansfield Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oral cavity and oropharynx: a randomized study AJR Am J Roentgenol 126 1976 229 235
    • (1976) AJR Am J Roentgenol , vol.126 , pp. 229-235
    • Lo, T.C.1    Wiley Jr., A.L.2    Ansfield, F.J.3
  • 31
    • 0028020603 scopus 로고
    • Placebo-controlled randomized trial of infusional fluorouracil during standard radiotherapy in locally advanced head and neck cancer
    • G.P. Browman, C. Cripps, and D.I. Hodson Placebo-controlled randomized trial of infusional fluorouracil during standard radiotherapy in locally advanced head and neck cancer J Clin Oncol 12 1994 2648 2653
    • (1994) J Clin Oncol , vol.12 , pp. 2648-2653
    • Browman, G.P.1    Cripps, C.2    Hodson, D.I.3
  • 32
    • 0029877222 scopus 로고    scopus 로고
    • Concurrent radiotherapy and continuous ambulatory infusion 5-fluorouracil in advanced head and neck cancer
    • I.N. Olver, P.G. Hughes, and J.G. Smith Concurrent radiotherapy and continuous ambulatory infusion 5-fluorouracil in advanced head and neck cancer Eur J Cancer 32A 1996 249 254
    • (1996) Eur J Cancer , vol.32 , pp. 249-254
    • Olver, I.N.1    Hughes, P.G.2    Smith, J.G.3
  • 33
    • 0037208591 scopus 로고    scopus 로고
    • An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer
    • D.J. Adelstein, Y. Li, and G.L. Adams An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer J Clin Oncol 21 2003 92 98
    • (2003) J Clin Oncol , vol.21 , pp. 92-98
    • Adelstein, D.J.1    Li, Y.2    Adams, G.L.3
  • 34
    • 0036498665 scopus 로고    scopus 로고
    • Maximizing local control and organ preservation in stage IV squamous cell head and neck cancer with hyperfractionated radiation and concurrent chemotherapy
    • D.J. Adelstein, J.P. Saxton, and P. Lavertu Maximizing local control and organ preservation in stage IV squamous cell head and neck cancer with hyperfractionated radiation and concurrent chemotherapy J Clin Oncol 20 2002 1405 1410
    • (2002) J Clin Oncol , vol.20 , pp. 1405-1410
    • Adelstein, D.J.1    Saxton, J.P.2    Lavertu, P.3
  • 35
    • 0034651902 scopus 로고    scopus 로고
    • Mature results of a phase III randomized trial comparing concurrent chemoradiotherapy with radiation therapy alone in patients with stage III and IV squamous cell carcinoma of the head and neck
    • D.J. Adelstein, P. Lavertu, and J.P. Saxton Mature results of a phase III randomized trial comparing concurrent chemoradiotherapy with radiation therapy alone in patients with stage III and IV squamous cell carcinoma of the head and neck Cancer 88 2000 876 883
    • (2000) Cancer , vol.88 , pp. 876-883
    • Adelstein, D.J.1    Lavertu, P.2    Saxton, J.P.3
  • 36
    • 0242500947 scopus 로고    scopus 로고
    • Neoadjuvant preoperative chemoradiation in patients with pancreatic cancer
    • V. Magnin, V. Moutardier, and M.H. Giovannini Neoadjuvant preoperative chemoradiation in patients with pancreatic cancer Int J Radiat Oncol Biol Phys 55 2003 1300 1304
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 1300-1304
    • Magnin, V.1    Moutardier, V.2    Giovannini, M.H.3
  • 37
    • 0037321150 scopus 로고    scopus 로고
    • Surgical resection after preoperative chemoradiotherapy benefits selected patients with unresectable pancreatic cancer
    • J. Aristu, R. Canon, and F. Pardo Surgical resection after preoperative chemoradiotherapy benefits selected patients with unresectable pancreatic cancer Am J Clin Oncol 26 2003 30 36
    • (2003) Am J Clin Oncol , vol.26 , pp. 30-36
    • Aristu, J.1    Canon, R.2    Pardo, F.3
  • 38
    • 0036678456 scopus 로고    scopus 로고
    • Locally advanced pancreatic cancer treated with radiation and 5-fluorouracil
    • S. Mawdsley, M. Hall, and R. Glynne-Jones Locally advanced pancreatic cancer treated with radiation and 5-fluorouracil Clin Oncol (R Coll Radiol) 14 2002 308 312
    • (2002) Clin Oncol (R Coll Radiol) , vol.14 , pp. 308-312
    • Mawdsley, S.1    Hall, M.2    Glynne-Jones, R.3
  • 39
    • 0036569654 scopus 로고    scopus 로고
    • Length and quality of survival after external-beam radiotherapy with concurrent continuous 5-fluorouracil infusion for locally unresectable pancreatic cancer
    • H. Shinchi, S. Takao, and H. Noma Length and quality of survival after external-beam radiotherapy with concurrent continuous 5-fluorouracil infusion for locally unresectable pancreatic cancer Int J Radiat Oncol Biol Phys 53 2002 146 150
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 146-150
    • Shinchi, H.1    Takao, S.2    Noma, H.3
  • 40
    • 0036549518 scopus 로고    scopus 로고
    • Preoperative chemoradiation in the management of adenocarcinoma of the body of the pancreas
    • J.P. Arnoletti, J.P. Hoffman, and E.A. Ross Preoperative chemoradiation in the management of adenocarcinoma of the body of the pancreas Am Surg 68 2002 330 335 [discussion: 335-6]
    • (2002) Am Surg , vol.68 , pp. 330-335
    • Arnoletti, J.P.1    Hoffman, J.P.2    Ross, E.A.3
  • 41
    • 0035051095 scopus 로고    scopus 로고
    • Protracted venous infusion 5-fluorouracil with concomitant radiotherapy compared with bolus 5-fluorouracil for unresectable pancreatic cancer
    • V.K. Mehta, J.C. Poen, and J.M. Ford Protracted venous infusion 5-fluorouracil with concomitant radiotherapy compared with bolus 5-fluorouracil for unresectable pancreatic cancer Am J Clin Oncol 24 2001 155 159
    • (2001) Am J Clin Oncol , vol.24 , pp. 155-159
    • Mehta, V.K.1    Poen, J.C.2    Ford, J.M.3
  • 42
    • 0035501222 scopus 로고    scopus 로고
    • Radiotherapy and continuous infusion 5-fluorouracil in patients with nonresectable pancreatic carcinoma
    • G. Boz, A. De Paoli, and R. Innocente Radiotherapy and continuous infusion 5-fluorouracil in patients with nonresectable pancreatic carcinoma Int J Radiat Oncol Biol Phys 51 2001 736 740
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 736-740
    • Boz, G.1    De Paoli, A.2    Innocente, R.3
  • 43
    • 0034566044 scopus 로고    scopus 로고
    • Adjuvant radiotherapy and concomitant 5-fluorouracil by protracted venous infusion for resected pancreatic cancer
    • V.K. Mehta, G.A. Fisher, and J.M. Ford Adjuvant radiotherapy and concomitant 5-fluorouracil by protracted venous infusion for resected pancreatic cancer Int J Radiat Oncol Biol Phys 48 2000 1483 1487
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 1483-1487
    • Mehta, V.K.1    Fisher, G.A.2    Ford, J.M.3
  • 44
    • 0034333248 scopus 로고    scopus 로고
    • Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: Acceptable toxicity and suggestion of improved 1-year disease-free survival
    • A. Chakravarthy, R.A. Abrams, and C.J. Yeo Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival Int J Radiat Oncol Biol Phys 48 2000 1089 1096
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 1089-1096
    • Chakravarthy, A.1    Abrams, R.A.2    Yeo, C.J.3
  • 45
    • 0032784821 scopus 로고    scopus 로고
    • Intensified adjuvant therapy for pancreatic and periampullary adenocarcinoma: Survival results and observations regarding patterns of failure, radiotherapy dose and CA19-9 levels
    • R.A. Abrams, L.B. Grochow, and A. Chakravarthy Intensified adjuvant therapy for pancreatic and periampullary adenocarcinoma: survival results and observations regarding patterns of failure, radiotherapy dose and CA19-9 levels Int J Radiat Oncol Biol Phys 44 1999 1039 1046
    • (1999) Int J Radiat Oncol Biol Phys , vol.44 , pp. 1039-1046
    • Abrams, R.A.1    Grochow, L.B.2    Chakravarthy, A.3
  • 46
    • 0037083482 scopus 로고    scopus 로고
    • Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix
    • R. Pearcey, M. Brundage, and P. Drouin Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix J Clin Oncol 20 2002 966 972
    • (2002) J Clin Oncol , vol.20 , pp. 966-972
    • Pearcey, R.1    Brundage, M.2    Drouin, P.3
  • 47
    • 0033561259 scopus 로고    scopus 로고
    • Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma
    • H.M. Keys, B.N. Bundy, and F.B. Stehman Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma N Engl J Med 340 1999 1154 1161
    • (1999) N Engl J Med , vol.340 , pp. 1154-1161
    • Keys, H.M.1    Bundy, B.N.2    Stehman, F.B.3
  • 48
    • 0033023214 scopus 로고    scopus 로고
    • Chemoradiation and adjuvant chemotherapy in cervical cancer
    • L.C. Wong, H.Y. Ngan, and A.N. Cheung Chemoradiation and adjuvant chemotherapy in cervical cancer J Clin Oncol 17 1999 2055 2060
    • (1999) J Clin Oncol , vol.17 , pp. 2055-2060
    • Wong, L.C.1    Ngan, H.Y.2    Cheung, A.N.3
  • 49
    • 0033993937 scopus 로고    scopus 로고
    • Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix
    • W.A. Peters III, P.Y. Liu, and R.J. Barrett II Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix J Clin Oncol 18 2000 1606 1613
    • (2000) J Clin Oncol , vol.18 , pp. 1606-1613
    • Peters III, W.A.1    Liu, P.Y.2    Barrett II, R.J.3
  • 50
    • 0033561333 scopus 로고    scopus 로고
    • Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer
    • P.G. Rose, B.N. Bundy, and E.B. Watkins Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer N Engl J Med 340 1999 1144 1153
    • (1999) N Engl J Med , vol.340 , pp. 1144-1153
    • Rose, P.G.1    Bundy, B.N.2    Watkins, E.B.3
  • 51
    • 0033561204 scopus 로고    scopus 로고
    • Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer
    • M. Morris, P.J. Eifel, and J. Lu Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer N Engl J Med 340 1999 1137 1143
    • (1999) N Engl J Med , vol.340 , pp. 1137-1143
    • Morris, M.1    Eifel, P.J.2    Lu, J.3
  • 52
    • 0034651755 scopus 로고    scopus 로고
    • The National Cancer Data Base report on poor survival of US gastric carcinoma patients treated with gastrectomy: Fifth Edition American Joint Committee on Cancer Staging, Proximal Disease, and the "different Disease" Hypothesis
    • S.A. Hundahl, J.L. Phillips, and H.R. Menck The National Cancer Data Base report on poor survival of US gastric carcinoma patients treated with gastrectomy: Fifth Edition American Joint Committee on Cancer Staging, Proximal Disease, and the "Different Disease" Hypothesis Cancer 88 2000 921 932
    • (2000) Cancer , vol.88 , pp. 921-932
    • Hundahl, S.A.1    Phillips, J.L.2    Menck, H.R.3
  • 53
    • 0022649682 scopus 로고
    • Combined 5-fluorouracil (5-FU) and radiation therapy following resection of locally advanced gastric carcinoma
    • E. Gez, A. Sulkes, and T. Yablonsky-Peretz Combined 5-fluorouracil (5-FU) and radiation therapy following resection of locally advanced gastric carcinoma J Surg Oncol 31 1986 139 142
    • (1986) J Surg Oncol , vol.31 , pp. 139-142
    • Gez, E.1    Sulkes, A.2    Yablonsky-Peretz, T.3
  • 55
    • 0031113702 scopus 로고    scopus 로고
    • Preoperative chemoradiation and adjuvant surgery in locally advanced or recurrent cervical carcinoma
    • R. Martinez Monge, M. Jurado, and I. Azinovic Preoperative chemoradiation and adjuvant surgery in locally advanced or recurrent cervical carcinoma Rev Med Univ Navarra 41 1997 19 26
    • (1997) Rev Med Univ Navarra , vol.41 , pp. 19-26
    • Martinez Monge, R.1    Jurado, M.2    Azinovic, I.3
  • 56
    • 0035818048 scopus 로고    scopus 로고
    • Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction
    • J.S. Macdonald, S.R. Smalley, and J. Benedetti Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction N Engl J Med 345 2001 725 730
    • (2001) N Engl J Med , vol.345 , pp. 725-730
    • MacDonald, J.S.1    Smalley, S.R.2    Benedetti, J.3
  • 57
    • 0035260554 scopus 로고    scopus 로고
    • [Simultaneous chemotherapy/radiotherapy in locally advanced unresectable cancer of the bladder]
    • B. Paule, and F. Saint [Simultaneous chemotherapy/radiotherapy in locally advanced unresectable cancer of the bladder] Prog Urol 11 2001 132 140 [in French]
    • (2001) Prog Urol , vol.11 , pp. 132-140
    • Paule, B.1    Saint, F.2
  • 58
    • 0025314276 scopus 로고
    • Treatment of advanced transitional cell carcinoma of the bladder with irradiation and concomitant 5-fluorouracil infusion
    • M. Rotman, H. Aziz, and M. Porrazzo Treatment of advanced transitional cell carcinoma of the bladder with irradiation and concomitant 5-fluorouracil infusion Int J Radiat Oncol Biol Phys 18 1990 1131 1137
    • (1990) Int J Radiat Oncol Biol Phys , vol.18 , pp. 1131-1137
    • Rotman, M.1    Aziz, H.2    Porrazzo, M.3
  • 59
    • 0025005720 scopus 로고
    • Combined 5-fluorouracil and irradiation for transitional cell carcinoma of the urinary bladder
    • K.J. Russell, M.A. Boileau, and C. Higano Combined 5-fluorouracil and irradiation for transitional cell carcinoma of the urinary bladder Int J Radiat Oncol Biol Phys 19 1990 693 699
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 693-699
    • Russell, K.J.1    Boileau, M.A.2    Higano, C.3
  • 60
    • 0035458537 scopus 로고    scopus 로고
    • Location, not staging, of cholangiocarcinoma determines the role for adjuvant chemoradiation therapy
    • F.M. Serafini, D. Sachs, and M. Bloomston Location, not staging, of cholangiocarcinoma determines the role for adjuvant chemoradiation therapy Am Surg 67 2001 839 843 [discussion: 843-4]
    • (2001) Am Surg , vol.67 , pp. 839-843
    • Serafini, F.M.1    Sachs, D.2    Bloomston, M.3
  • 61
    • 0036776052 scopus 로고    scopus 로고
    • Improved survival in resected biliary malignancies
    • A. Nakeeb, K.Q. Tran, and M.J. Black Improved survival in resected biliary malignancies Surgery 132 2002 555 563 [discussion: 563-4]
    • (2002) Surgery , vol.132 , pp. 555-563
    • Nakeeb, A.1    Tran, K.Q.2    Black, M.J.3
  • 62
    • 0026735637 scopus 로고
    • Radiosensitization of cultured human colon adenocarcinoma cells by 5-fluorouracil: Effects on cell survival, DNA repair, and cell recovery
    • L.L. Hughes, J. Luengas, and T.A. Rich Radiosensitization of cultured human colon adenocarcinoma cells by 5-fluorouracil: effects on cell survival, DNA repair, and cell recovery Int J Radiat Oncol Biol Phys 23 1992 983 991
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , pp. 983-991
    • Hughes, L.L.1    Luengas, J.2    Rich, T.A.3
  • 63
    • 0032695102 scopus 로고    scopus 로고
    • X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts
    • N. Sawada, T. Ishikawa, and F. Sekiguchi X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts Clin Cancer Res 5 1999 2948 2953
    • (1999) Clin Cancer Res , vol.5 , pp. 2948-2953
    • Sawada, N.1    Ishikawa, T.2    Sekiguchi, F.3
  • 64
    • 0032127244 scopus 로고    scopus 로고
    • Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
    • M. Miwa, M. Ura, and M. Nishida Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue Eur J Cancer 34 1998 1274 1281
    • (1998) Eur J Cancer , vol.34 , pp. 1274-1281
    • Miwa, M.1    Ura, M.2    Nishida, M.3
  • 65
    • 0034016415 scopus 로고    scopus 로고
    • Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients
    • J. Schuller, J. Cassidy, and E. Dumont Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients Cancer Chemother Pharmacol 45 2000 291 297
    • (2000) Cancer Chemother Pharmacol , vol.45 , pp. 291-297
    • Schuller, J.1    Cassidy, J.2    Dumont, E.3
  • 66
    • 0024318282 scopus 로고
    • Cellular pharmacology of fluorinated pyrimidines in vivo in man
    • J.S. Kovach, and R.W. Beart Jr Cellular pharmacology of fluorinated pyrimidines in vivo in man Invest New Drugs 7 1989 13 25
    • (1989) Invest New Drugs , vol.7 , pp. 13-25
    • Kovach, J.S.1    Beart Jr., R.W.2
  • 67
    • 0032874395 scopus 로고    scopus 로고
    • The oral fluoropyrimidines in cancer chemotherapy
    • E.B. Lamont, and R.L. Schilsky The oral fluoropyrimidines in cancer chemotherapy Clin Cancer Res 5 1999 2289 2296
    • (1999) Clin Cancer Res , vol.5 , pp. 2289-2296
    • Lamont, E.B.1    Schilsky, R.L.2
  • 68
    • 0034745284 scopus 로고    scopus 로고
    • Capecitabine (Xeloda) improves medical resource use compared with 5-fluorouracil plus leucovorin in a phase III trial conducted in patients with advanced colorectal carcinoma
    • C. Twelves, M. Boyer, and M. Findlay Capecitabine (Xeloda) improves medical resource use compared with 5-fluorouracil plus leucovorin in a phase III trial conducted in patients with advanced colorectal carcinoma Eur J Cancer 37 2001 597 604
    • (2001) Eur J Cancer , vol.37 , pp. 597-604
    • Twelves, C.1    Boyer, M.2    Findlay, M.3
  • 69
    • 9744278998 scopus 로고    scopus 로고
    • Efficacy and safety of single agent capecitabine in pretreated metastatic breast cancer patients from the French compassionate use program
    • J.Y. Pierga, P. Fumoleau, and Y. Brewer Efficacy and safety of single agent capecitabine in pretreated metastatic breast cancer patients from the French compassionate use program Breast Cancer Res Treat 88 2004 117 129
    • (2004) Breast Cancer Res Treat , vol.88 , pp. 117-129
    • Pierga, J.Y.1    Fumoleau, P.2    Brewer, Y.3
  • 70
    • 21144452813 scopus 로고    scopus 로고
    • Capecitabine as first-line treatment for patients older than 70 years with metastatic colorectal cancer: An Oncopaz cooperative group study
    • J. Feliu, P. Escudero, and F. Llosa Capecitabine as first-line treatment for patients older than 70 years with metastatic colorectal cancer: an Oncopaz cooperative group study J Clin Oncol 23 2005 3104 3111
    • (2005) J Clin Oncol , vol.23 , pp. 3104-3111
    • Feliu, J.1    Escudero, P.2    Llosa, F.3
  • 71
    • 14844303761 scopus 로고    scopus 로고
    • Capecitabine: A review
    • C.M. Walko, and C. Lindley Capecitabine: a review Clin Ther 27 2005 23 44
    • (2005) Clin Ther , vol.27 , pp. 23-44
    • Walko, C.M.1    Lindley, C.2
  • 72
    • 0036787579 scopus 로고    scopus 로고
    • Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer
    • J. Dunst, T. Reese, and T. Sutter Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer J Clin Oncol 20 2002 3983 3991
    • (2002) J Clin Oncol , vol.20 , pp. 3983-3991
    • Dunst, J.1    Reese, T.2    Sutter, T.3
  • 73
    • 0041912759 scopus 로고    scopus 로고
    • Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer
    • C. Rodel, G.G. Grabenbauer, and T. Papadopoulos Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer J Clin Oncol 21 2003 3098 3104
    • (2003) J Clin Oncol , vol.21 , pp. 3098-3104
    • Rodel, C.1    Grabenbauer, G.G.2    Papadopoulos, T.3
  • 74
    • 0025273308 scopus 로고
    • Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin
    • C.M. Sorenson, M.A. Barry, and A. Eastman Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin J Natl Cancer Inst 82 1990 749 755
    • (1990) J Natl Cancer Inst , vol.82 , pp. 749-755
    • Sorenson, C.M.1    Barry, M.A.2    Eastman, A.3
  • 75
    • 0021199197 scopus 로고
    • Toxic variability and radiation sensitization by dichlorodiammineplatinum(II) complexes in Salmonella typhimurium cells
    • R.C. Richmond Toxic variability and radiation sensitization by dichlorodiammineplatinum(II) complexes in Salmonella typhimurium cells Radiat Res 99 1984 596 608
    • (1984) Radiat Res , vol.99 , pp. 596-608
    • Richmond, R.C.1
  • 76
    • 0032962339 scopus 로고    scopus 로고
    • Radiopotentiation by the oral platinum agent, JM216: Role of repair inhibition
    • G.P. Amorino, M.L. Freeman, and D.P. Carbone Radiopotentiation by the oral platinum agent, JM216: role of repair inhibition Int J Radiat Oncol Biol Phys 44 1999 399 405
    • (1999) Int J Radiat Oncol Biol Phys , vol.44 , pp. 399-405
    • Amorino, G.P.1    Freeman, M.L.2    Carbone, D.P.3
  • 78
    • 0035050647 scopus 로고    scopus 로고
    • The novel trinuclear platinum complex BBR3464 induces a cellular response different from cisplatin
    • T. Servidei, C. Ferlini, and A. Riccardi The novel trinuclear platinum complex BBR3464 induces a cellular response different from cisplatin Eur J Cancer 37 2001 930 938
    • (2001) Eur J Cancer , vol.37 , pp. 930-938
    • Servidei, T.1    Ferlini, C.2    Riccardi, A.3
  • 79
    • 14844353135 scopus 로고    scopus 로고
    • Radiation sensitizers: A selective review of molecules targeting DNA and non-DNA targets
    • L.K. Kvols Radiation sensitizers: a selective review of molecules targeting DNA and non-DNA targets J Nucl Med 46 Suppl 1 2005 187S 190S
    • (2005) J Nucl Med , vol.46 , Issue.SUPPL. 1
    • Kvols, L.K.1
  • 80
    • 0021435857 scopus 로고
    • Drugs five years later. Cisplatin
    • P.J. Loehrer, and L.H. Einhorn Drugs five years later. Cisplatin Ann Intern Med 100 1984 704 713
    • (1984) Ann Intern Med , vol.100 , pp. 704-713
    • Loehrer, P.J.1    Einhorn, L.H.2
  • 81
    • 0025020085 scopus 로고
    • Phase I study of oxaliplatin in patients with advanced cancer
    • J.M. Extra, M. Espie, and F. Calvo Phase I study of oxaliplatin in patients with advanced cancer Cancer Chemother Pharmacol 25 1990 299 303
    • (1990) Cancer Chemother Pharmacol , vol.25 , pp. 299-303
    • Extra, J.M.1    Espie, M.2    Calvo, F.3
  • 82
    • 0012797224 scopus 로고    scopus 로고
    • Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines
    • D. Machover, E. Diaz-Rubio, and A. de Gramont Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines Ann Oncol 7 1996 95 98
    • (1996) Ann Oncol , vol.7 , pp. 95-98
    • MacHover, D.1    Diaz-Rubio, E.2    De Gramont, A.3
  • 83
    • 0033611522 scopus 로고    scopus 로고
    • Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide
    • A.T. Turrisi III, K. Kim, and R. Blum Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide N Engl J Med 340 1999 265 271
    • (1999) N Engl J Med , vol.340 , pp. 265-271
    • Turrisi III, A.T.1    Kim, K.2    Blum, R.3
  • 84
    • 0032823488 scopus 로고    scopus 로고
    • Chemoradiation for locally advanced, unresectable NSCLC. New standard of care, emerging strategies
    • G.S. Gordon, and E.E. Vokes Chemoradiation for locally advanced, unresectable NSCLC. New standard of care, emerging strategies Oncology (Williston Park) 13 1999 1075 1088 [discussion: 1088, 1091-4]
    • (1999) Oncology (Williston Park) , vol.13 , pp. 1075-1088
    • Gordon, G.S.1    Vokes, E.E.2
  • 85
    • 0037102282 scopus 로고    scopus 로고
    • Concurrent cisplatin, etoposide, and chest radiotherapy in pathologic stage IIIB non-small-cell lung cancer: A Southwest Oncology Group phase II study, SWOG 9019
    • K.S. Albain, J.J. Crowley, and A.T. Turrisi III Concurrent cisplatin, etoposide, and chest radiotherapy in pathologic stage IIIB non-small-cell lung cancer: a Southwest Oncology Group phase II study, SWOG 9019 J Clin Oncol 20 2002 3454 3460
    • (2002) J Clin Oncol , vol.20 , pp. 3454-3460
    • Albain, K.S.1    Crowley, J.J.2    Turrisi III, A.T.3
  • 86
    • 0034975986 scopus 로고    scopus 로고
    • Choosing a concomitant chemotherapy and radiotherapy regimen for squamous cell head and neck cancer: A systematic review of the published literature with subgroup analysis
    • G.P. Browman, D.I. Hodson, and R.J. Mackenzie Choosing a concomitant chemotherapy and radiotherapy regimen for squamous cell head and neck cancer: a systematic review of the published literature with subgroup analysis Head Neck 23 2001 579 589
    • (2001) Head Neck , vol.23 , pp. 579-589
    • Browman, G.P.1    Hodson, D.I.2    MacKenzie, R.J.3
  • 87
    • 25444503968 scopus 로고    scopus 로고
    • A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer
    • C. Aschele, M.L. Friso, and S. Pucciarelli A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer Ann Oncol 16 2005 1140 1146
    • (2005) Ann Oncol , vol.16 , pp. 1140-1146
    • Aschele, C.1    Friso, M.L.2    Pucciarelli, S.3
  • 88
    • 0035340318 scopus 로고    scopus 로고
    • Addition of oxaliplatin to continuous fluorouracil, l-folinic acid, and concomitant radiotherapy in rectal cancer: The Lyon R 97-03 phase I trial
    • G. Freyer, N. Bossard, and P. Romestaing Addition of oxaliplatin to continuous fluorouracil, l-folinic acid, and concomitant radiotherapy in rectal cancer: the Lyon R 97-03 phase I trial J Clin Oncol 19 2001 2433 2438
    • (2001) J Clin Oncol , vol.19 , pp. 2433-2438
    • Freyer, G.1    Bossard, N.2    Romestaing, P.3
  • 89
    • 0037445116 scopus 로고    scopus 로고
    • Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: The Lyon R0-04 phase II trial
    • J.P. Gerard, O. Chapet, and C. Nemoz Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: the Lyon R0-04 phase II trial J Clin Oncol 21 2003 1119 1124
    • (2003) J Clin Oncol , vol.21 , pp. 1119-1124
    • Gerard, J.P.1    Chapet, O.2    Nemoz, C.3
  • 90
    • 0026324313 scopus 로고
    • Action of 2′,2′-difluorodeoxycytidine on DNA synthesis
    • P. Huang, S. Chubb, and L.W. Hertel Action of 2′,2′- difluorodeoxycytidine on DNA synthesis Cancer Res 51 1991 6110 6117
    • (1991) Cancer Res , vol.51 , pp. 6110-6117
    • Huang, P.1    Chubb, S.2    Hertel, L.W.3
  • 91
    • 0028062981 scopus 로고
    • Molecular effects of 2′,2′-difluorodeoxycytidine (Gemcitabine) on DNA replication in intact HL-60 cells
    • D.D. Ross, and D.P. Cuddy Molecular effects of 2′,2′- difluorodeoxycytidine (Gemcitabine) on DNA replication in intact HL-60 cells Biochem Pharmacol 48 1994 1619 1630
    • (1994) Biochem Pharmacol , vol.48 , pp. 1619-1630
    • Ross, D.D.1    Cuddy, D.P.2
  • 92
    • 0028240063 scopus 로고
    • Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells
    • D.S. Shewach, T.M. Hahn, and E. Chang Metabolism of 2′,2′- difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells Cancer Res 54 1994 3218 3223
    • (1994) Cancer Res , vol.54 , pp. 3218-3223
    • Shewach, D.S.1    Hahn, T.M.2    Chang, E.3
  • 93
    • 0031804603 scopus 로고    scopus 로고
    • Radiosensitizing potential of gemcitabine (2′,2′-difluoro- 2′-deoxycytidine) within the cell cycle in vitro
    • D. Latz, K. Fleckenstein, and M. Eble Radiosensitizing potential of gemcitabine (2′,2′-difluoro-2′-deoxycytidine) within the cell cycle in vitro Int J Radiat Oncol Biol Phys 41 1998 875 882
    • (1998) Int J Radiat Oncol Biol Phys , vol.41 , pp. 875-882
    • Latz, D.1    Fleckenstein, K.2    Eble, M.3
  • 94
    • 0034880820 scopus 로고    scopus 로고
    • Phase I trial of gemcitabine combined with radiation for the treatment of locally advanced pancreatic adenocarcinoma
    • R.A. Wolff, D.B. Evans, and D.M. Gravel Phase I trial of gemcitabine combined with radiation for the treatment of locally advanced pancreatic adenocarcinoma Clin Cancer Res 7 2001 2246 2253
    • (2001) Clin Cancer Res , vol.7 , pp. 2246-2253
    • Wolff, R.A.1    Evans, D.B.2    Gravel, D.M.3
  • 95
    • 0034306137 scopus 로고    scopus 로고
    • Eastern Cooperative Oncology Group Phase I trial of protracted venous infusion fluorouracil plus weekly gemcitabine with concurrent radiation therapy in patients with locally advanced pancreas cancer: A regimen with unexpected early toxicity
    • M.S. Talamonti, P.J. Catalano, and D.J. Vaughn Eastern Cooperative Oncology Group Phase I trial of protracted venous infusion fluorouracil plus weekly gemcitabine with concurrent radiation therapy in patients with locally advanced pancreas cancer: a regimen with unexpected early toxicity J Clin Oncol 18 2000 3384 3389
    • (2000) J Clin Oncol , vol.18 , pp. 3384-3389
    • Talamonti, M.S.1    Catalano, P.J.2    Vaughn, D.J.3
  • 96
    • 0037783798 scopus 로고    scopus 로고
    • Clinical research in pancreatic cancer: The Radiation Therapy Oncology Group trials
    • C.G. Willett, H. Safran, and R.A. Abrams Clinical research in pancreatic cancer: the Radiation Therapy Oncology Group trials Int J Radiat Oncol Biol Phys 56 2003 31 37
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 31-37
    • Willett, C.G.1    Safran, H.2    Abrams, R.A.3
  • 97
    • 8944261362 scopus 로고    scopus 로고
    • A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer
    • M.L. Rothenberg, M.J. Moore, and M.C. Cripps A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer Ann Oncol 7 1996 347 353
    • (1996) Ann Oncol , vol.7 , pp. 347-353
    • Rothenberg, M.L.1    Moore, M.J.2    Cripps, M.C.3
  • 98
    • 27244456183 scopus 로고    scopus 로고
    • Phase I/IIa study of cisplatin and gemcitabine as induction chemotherapy followed by concurrent chemoradiotherapy with gemcitabine and paclitaxel for locally advanced non-small-cell lung cancer
    • S.G. Divers, S.A. Spencer, and D. Carey Phase I/IIa study of cisplatin and gemcitabine as induction chemotherapy followed by concurrent chemoradiotherapy with gemcitabine and paclitaxel for locally advanced non-small-cell lung cancer J Clin Oncol 23 2005 6664 6673
    • (2005) J Clin Oncol , vol.23 , pp. 6664-6673
    • Divers, S.G.1    Spencer, S.A.2    Carey, D.3
  • 99
    • 12844285162 scopus 로고    scopus 로고
    • Phase I study of conformal radiotherapy with concurrent gemcitabine in locally advanced bladder cancer
    • V.K. Sangar, C.A. McBain, and J. Lyons Phase I study of conformal radiotherapy with concurrent gemcitabine in locally advanced bladder cancer Int J Radiat Oncol Biol Phys 61 2005 420 425
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , pp. 420-425
    • Sangar, V.K.1    McBain, C.A.2    Lyons, J.3
  • 100
    • 11144291099 scopus 로고    scopus 로고
    • Current status of radiation therapy and combined-modality treatment for bladder cancer
    • C. Rodel Current status of radiation therapy and combined-modality treatment for bladder cancer Strahlentherapie und Onkologie 180 2004 701 709
    • (2004) Strahlentherapie und Onkologie , vol.180 , pp. 701-709
    • Rodel, C.1
  • 101
    • 0033199927 scopus 로고    scopus 로고
    • Enhancement of tumor response to gamma-radiation by an inhibitor of cyclooxygenase-2 enzyme
    • L. Milas, K. Kishi, and N. Hunter Enhancement of tumor response to gamma-radiation by an inhibitor of cyclooxygenase-2 enzyme J Natl Cancer Inst 91 1999 1501 1504
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1501-1504
    • Milas, L.1    Kishi, K.2    Hunter, N.3
  • 102
    • 23244466695 scopus 로고    scopus 로고
    • Radiation interactions with taxanes, old and new
    • K.A. Mason Radiation interactions with taxanes, old and new Radiat Res 163 2005 705 706
    • (2005) Radiat Res , vol.163 , pp. 705-706
    • Mason, K.A.1
  • 103
    • 0037358299 scopus 로고    scopus 로고
    • Poly(L-glutamic acid)-paclitaxel conjugate is a potent enhancer of tumor radiocurability
    • L. Milas, K.A. Mason, and N. Hunter Poly(L-glutamic acid)-paclitaxel conjugate is a potent enhancer of tumor radiocurability Int J Radiat Oncol Biol Phys 55 2003 707 712
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 707-712
    • Milas, L.1    Mason, K.A.2    Hunter, N.3
  • 104
    • 0035111779 scopus 로고    scopus 로고
    • Taxanes in combined modality therapy for solid tumors
    • H. Choy Taxanes in combined modality therapy for solid tumors Crit Rev Oncol Hematol 37 2001 237 247
    • (2001) Crit Rev Oncol Hematol , vol.37 , pp. 237-247
    • Choy, H.1
  • 105
    • 0031771981 scopus 로고    scopus 로고
    • Camptothecin radiation sensitization: Mechanisms, schedules, and timing
    • T.A. Rich, and A.V. Kirichenko Camptothecin radiation sensitization: mechanisms, schedules, and timing Oncology (Williston Park) 12 1998 114 120
    • (1998) Oncology (Williston Park) , vol.12 , pp. 114-120
    • Rich, T.A.1    Kirichenko, A.V.2
  • 106
    • 0033212103 scopus 로고    scopus 로고
    • DNA topoisomerase I-targeting drugs as radiation sensitizers
    • A.Y. Chen, H. Choy, and M.L. Rothenberg DNA topoisomerase I-targeting drugs as radiation sensitizers Oncology (Williston Park) 13 1999 39 46
    • (1999) Oncology (Williston Park) , vol.13 , pp. 39-46
    • Chen, A.Y.1    Choy, H.2    Rothenberg, M.L.3
  • 107
    • 0030892634 scopus 로고    scopus 로고
    • Enhancement of tumor radio-response by irinotecan in human lung tumor xenografts
    • K. Tamura, M. Takada, and I. Kawase Enhancement of tumor radio-response by irinotecan in human lung tumor xenografts Jpn J Cancer Res 88 1997 218 223
    • (1997) Jpn J Cancer Res , vol.88 , pp. 218-223
    • Tamura, K.1    Takada, M.2    Kawase, I.3
  • 108
    • 0029935610 scopus 로고    scopus 로고
    • Enhancement of the antitumor effect of gamma-ray irradiation in combination with camptothecin against human colorectal adenocarcinoma
    • D.S. Wang, Y. Ueno, and H. Oyamada Enhancement of the antitumor effect of gamma-ray irradiation in combination with camptothecin against human colorectal adenocarcinoma Biol Pharm Bull 19 1996 354 359
    • (1996) Biol Pharm Bull , vol.19 , pp. 354-359
    • Wang, D.S.1    Ueno, Y.2    Oyamada, H.3
  • 109
    • 0028328850 scopus 로고
    • Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells
    • C. Hennequin, N. Giocanti, and J. Balosso Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells Cancer Res 54 1994 1720 1728
    • (1994) Cancer Res , vol.54 , pp. 1720-1728
    • Hennequin, C.1    Giocanti, N.2    Balosso, J.3
  • 110
    • 0027529978 scopus 로고
    • Interaction of topoisomerase I inhibitors with radiation in cis-diamminedichloroplatinum(II)-sensitive and -resistant cells in vitro and in the FSAIIC fibrosarcoma in vivo
    • R.E. Boscia, T. Korbut, and S.A. Holden Interaction of topoisomerase I inhibitors with radiation in cis-diamminedichloroplatinum(II)-sensitive and -resistant cells in vitro and in the FSAIIC fibrosarcoma in vivo Int J Cancer 53 1993 118 123
    • (1993) Int J Cancer , vol.53 , pp. 118-123
    • Boscia, R.E.1    Korbut, T.2    Holden, S.A.3
  • 111
    • 0242578674 scopus 로고    scopus 로고
    • Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer
    • A.X. Zhu, and C.G. Willett Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer Semin Radiat Oncol 13 2003 454 468
    • (2003) Semin Radiat Oncol , vol.13 , pp. 454-468
    • Zhu, A.X.1    Willett, C.G.2
  • 112
    • 20144375332 scopus 로고    scopus 로고
    • Phase I trial of capecitabine and weekly irinotecan in combination with radiotherapy for neoadjuvant therapy of rectal cancer
    • R.D. Hofheinz, B. von Gerstenberg-Helldorf, and F. Wenz Phase I trial of capecitabine and weekly irinotecan in combination with radiotherapy for neoadjuvant therapy of rectal cancer J Clin Oncol 23 2005 1350 1357
    • (2005) J Clin Oncol , vol.23 , pp. 1350-1357
    • Hofheinz, R.D.1    Von Gerstenberg-Helldorf, B.2    Wenz, F.3
  • 113
    • 0042887575 scopus 로고    scopus 로고
    • Phase I trial of escalating-dose irinotecan given weekly with cisplatin and concurrent radiotherapy in locally advanced esophageal cancer
    • D.H. Ilson, M. Bains, and D.P. Kelsen Phase I trial of escalating-dose irinotecan given weekly with cisplatin and concurrent radiotherapy in locally advanced esophageal cancer J Clin Oncol 21 2003 2926 2932
    • (2003) J Clin Oncol , vol.21 , pp. 2926-2932
    • Ilson, D.H.1    Bains, M.2    Kelsen, D.P.3
  • 114
    • 0034162780 scopus 로고    scopus 로고
    • Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor
    • K. Kishi, S. Petersen, and C. Petersen Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor Cancer Res 60 2000 1326 1331
    • (2000) Cancer Res , vol.60 , pp. 1326-1331
    • Kishi, K.1    Petersen, S.2    Petersen, C.3
  • 115
    • 17444376781 scopus 로고    scopus 로고
    • Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin
    • D.H. Gorski, H.J. Mauceri, and R.M. Salloum Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin Cancer Res 58 1998 5686 5689
    • (1998) Cancer Res , vol.58 , pp. 5686-5689
    • Gorski, D.H.1    Mauceri, H.J.2    Salloum, R.M.3
  • 116
    • 18244419396 scopus 로고    scopus 로고
    • Combined effects of angiostatin and ionizing radiation in antitumour therapy
    • H.J. Mauceri, N.N. Hanna, and M.A. Beckett Combined effects of angiostatin and ionizing radiation in antitumour therapy Nature 394 1998 287 291
    • (1998) Nature , vol.394 , pp. 287-291
    • Mauceri, H.J.1    Hanna, N.N.2    Beckett, M.A.3
  • 117
    • 33645400454 scopus 로고    scopus 로고
    • US Food and Drug Administration
    • US Food and Drug Administration Available at: http://www.fda.gov/cder/ drug/infopage/cox2/default.htm
  • 118
    • 0000532787 scopus 로고
    • The oxygen effect and reoxygenation
    • 4th edition Lippincott, Williams & Wilkins
    • E.J. Hall The oxygen effect and reoxygenation Radiobiology for the radiologist 4th edition 1994 Lippincott, Williams & Wilkins 133 152
    • (1994) Radiobiology for the Radiologist , pp. 133-152
    • Hall, E.J.1
  • 119
    • 26444467146 scopus 로고    scopus 로고
    • Plasma osteopontin, hypoxia and response to hypoxic sensitiser nimorazole in radiotherapy of head and neck cancer: Results of DAHANCA 5 randomized double-blind placebo-controlled trial
    • The Danish Head and Neck Cancer Study Group M.
    • J. Overgaard, J.G. Erikson, M. Nordsmark The Danish Head and Neck Cancer Study Group Plasma osteopontin, hypoxia and response to hypoxic sensitiser nimorazole in radiotherapy of head and neck cancer: Results of DAHANCA 5 randomized double-blind placebo-controlled trial Lancet Oncol 6 10 2005 757 764 [Epub 2005 Aug 27]
    • (2005) Lancet Oncol , vol.6 , Issue.10 , pp. 757-764
    • Overgaard, J.1    Erikson, J.G.2    Nordsmark3
  • 120
    • 0030069889 scopus 로고    scopus 로고
    • Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers
    • J. Overgaard, and M.R. Horsman Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers Semin Radiat Oncol 6 1996 10 21
    • (1996) Semin Radiat Oncol , vol.6 , pp. 10-21
    • Overgaard, J.1    Horsman, M.R.2
  • 121
    • 0028632781 scopus 로고
    • Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors
    • J. Overgaard Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors Oncol Res 6 1994 509 518
    • (1994) Oncol Res , vol.6 , pp. 509-518
    • Overgaard, J.1
  • 122
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • J.M. Brown, and W.R. Wilson Exploiting tumour hypoxia in cancer treatment Nat Rev Cancer 4 2004 437 447
    • (2004) Nat Rev Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 124
    • 0031696089 scopus 로고    scopus 로고
    • Changes in tumor oxygenation during combined treatment with split-course radiotherapy and chemotherapy in patients with head and neck cancer
    • P. Stadler, H.J. Feldmann, and C. Creighton Changes in tumor oxygenation during combined treatment with split-course radiotherapy and chemotherapy in patients with head and neck cancer Radiother Oncol 48 1998 157 164
    • (1998) Radiother Oncol , vol.48 , pp. 157-164
    • Stadler, P.1    Feldmann, H.J.2    Creighton, C.3
  • 125
    • 0031297958 scopus 로고    scopus 로고
    • Bioreductive agents: A clinical update
    • M.J. Boyer Bioreductive agents: a clinical update Oncol Res 9 1997 391 395
    • (1997) Oncol Res , vol.9 , pp. 391-395
    • Boyer, M.J.1
  • 126
    • 1242271216 scopus 로고    scopus 로고
    • Hypoxia targeted gene therapy to increase the efficacy of tirapazamine as an adjuvant to radiotherapy: Reversing tumor radioresistance and effecting cure
    • R.L. Cowen, K.J. Williams, and E.C. Chinje Hypoxia targeted gene therapy to increase the efficacy of tirapazamine as an adjuvant to radiotherapy: reversing tumor radioresistance and effecting cure Cancer Res 64 2004 1396 1402
    • (2004) Cancer Res , vol.64 , pp. 1396-1402
    • Cowen, R.L.1    Williams, K.J.2    Chinje, E.C.3
  • 127
    • 1642475109 scopus 로고    scopus 로고
    • Selective potentiation of the hypoxic cytotoxicity of tirapazamine by its 1-N-oxide metabolite SR 4317
    • B.G. Siim, F.B. Pruijn, and J.R. Sturman Selective potentiation of the hypoxic cytotoxicity of tirapazamine by its 1-N-oxide metabolite SR 4317 Cancer Res 64 2004 736 742
    • (2004) Cancer Res , vol.64 , pp. 736-742
    • Siim, B.G.1    Pruijn, F.B.2    Sturman, J.R.3
  • 128
    • 0035132923 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts
    • S.V. Kozin, Y. Boucher, and D.J. Hicklin Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts Cancer Res 61 2001 39 44
    • (2001) Cancer Res , vol.61 , pp. 39-44
    • Kozin, S.V.1    Boucher, Y.2    Hicklin, D.J.3
  • 129
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • K.J. Kim, B. Li, and J. Winer Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo Nature 362 1993 841 844
    • (1993) Nature , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3
  • 130
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • D. Shweiki, A. Itin, and D. Soffer Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis Nature 359 1992 843 845
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3
  • 131
    • 22144495334 scopus 로고    scopus 로고
    • Angiogenesis and radiation response modulation after vascular endothelial growth factor receptor-2 (VEGFR2) blockade
    • J. Li, S. Huang, and E.A. Armstrong Angiogenesis and radiation response modulation after vascular endothelial growth factor receptor-2 (VEGFR2) blockade Int J Radiat Oncol Biol Phys 62 2005 1477 1485
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , pp. 1477-1485
    • Li, J.1    Huang, S.2    Armstrong, E.A.3
  • 132
    • 11144354392 scopus 로고    scopus 로고
    • Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
    • C.G. Willett, Y. Boucher, and E. di Tomaso Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer Nat Med 10 2004 145 147
    • (2004) Nat Med , vol.10 , pp. 145-147
    • Willett, C.G.1    Boucher, Y.2    Di Tomaso, E.3
  • 133
    • 0022387970 scopus 로고
    • Activated human N-ras oncogene enhances x-irradiation repair of mammalian cells in vitro less effectively at low dose rate. Implications for increased therapeutic ratio of low dose rate irradiation
    • T.J. FitzGerald, C. Daugherty, and K. Kase Activated human N-ras oncogene enhances x-irradiation repair of mammalian cells in vitro less effectively at low dose rate. Implications for increased therapeutic ratio of low dose rate irradiation Am J Clin Oncol 8 1985 517 522
    • (1985) Am J Clin Oncol , vol.8 , pp. 517-522
    • Fitzgerald, T.J.1    Daugherty, C.2    Kase, K.3
  • 134
    • 0023835721 scopus 로고
    • The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation
    • M.D. Sklar The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation Science 239 1988 645 647
    • (1988) Science , vol.239 , pp. 645-647
    • Sklar, M.D.1
  • 135
    • 0024363796 scopus 로고
    • Radioresistance induced by oncogenic transformation
    • C.C. Ling, and B. Endlich Radioresistance induced by oncogenic transformation Radiat Res 120 1989 267 279
    • (1989) Radiat Res , vol.120 , pp. 267-279
    • Ling, C.C.1    Endlich, B.2
  • 137
    • 0025191121 scopus 로고
    • Synergistic effect of the v-myc oncogene with H-ras on radioresistance
    • W.G. McKenna, M.C. Weiss, and B. Endlich Synergistic effect of the v-myc oncogene with H-ras on radioresistance Cancer Res 50 1990 97 102
    • (1990) Cancer Res , vol.50 , pp. 97-102
    • McKenna, W.G.1    Weiss, M.C.2    Endlich, B.3
  • 138
    • 0030966841 scopus 로고    scopus 로고
    • Functional aspects of apoptosis in hematopoiesis and consequences of failure
    • S.L. McKenna, and T.G. Cotter Functional aspects of apoptosis in hematopoiesis and consequences of failure Adv Cancer Res 71 1997 121 164
    • (1997) Adv Cancer Res , vol.71 , pp. 121-164
    • McKenna, S.L.1    Cotter, T.G.2
  • 139
    • 0029921232 scopus 로고    scopus 로고
    • The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts
    • E.J. Bernhard, G. Kao, and A.D. Cox The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts Cancer Res 56 1996 1727 1730
    • (1996) Cancer Res , vol.56 , pp. 1727-1730
    • Bernhard, E.J.1    Kao, G.2    Cox, A.D.3
  • 140
    • 0027473872 scopus 로고
    • Increased radioresistance of EJras-transformed human osteosarcoma cells and its modulation by lovastatin, an inhibitor of p21ras isoprenylation
    • A.C. Miller, K. Kariko, and C.E. Myers Increased radioresistance of EJras-transformed human osteosarcoma cells and its modulation by lovastatin, an inhibitor of p21ras isoprenylation Int J Cancer 53 1993 302 307
    • (1993) Int J Cancer , vol.53 , pp. 302-307
    • Miller, A.C.1    Kariko, K.2    Myers, C.E.3
  • 142
    • 0032695801 scopus 로고    scopus 로고
    • Radiosensitization of human tumor cell lines induced by the adenovirus-mediated expression of an anti-Ras single-chain antibody fragment
    • J.S. Russell, F.F. Lang, and T. Huet Radiosensitization of human tumor cell lines induced by the adenovirus-mediated expression of an anti-Ras single-chain antibody fragment Cancer Res 59 1999 5239 5244
    • (1999) Cancer Res , vol.59 , pp. 5239-5244
    • Russell, J.S.1    Lang, F.F.2    Huet, T.3
  • 143
    • 0030803735 scopus 로고    scopus 로고
    • Potential indicators of radiosensitivity in squamous cell carcinoma of the head and neck
    • M.T. Sheridan, T. O'Dwyer, and C.B. Seymour Potential indicators of radiosensitivity in squamous cell carcinoma of the head and neck Radiat Oncol Investig 5 1997 180 186
    • (1997) Radiat Oncol Investig , vol.5 , pp. 180-186
    • Sheridan, M.T.1    O'Dwyer, T.2    Seymour, C.B.3
  • 144
    • 0036638837 scopus 로고    scopus 로고
    • Epidermal growth factor receptor modulation of radiation response: Preclinical and clinical development
    • P.M. Harari, and S.M. Huang Epidermal growth factor receptor modulation of radiation response: preclinical and clinical development Semin Radiat Oncol 12 2002 21 26
    • (2002) Semin Radiat Oncol , vol.12 , pp. 21-26
    • Harari, P.M.1    Huang, S.M.2
  • 145
    • 0347928791 scopus 로고    scopus 로고
    • EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor
    • B. Solomon, J. Hagekyriakou, and M.K. Trivett EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor Int J Radiat Oncol Biol Phys 55 2003 713 723
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 713-723
    • Solomon, B.1    Hagekyriakou, J.2    Trivett, M.K.3
  • 146
    • 0037270588 scopus 로고    scopus 로고
    • Epidermal growth factor family receptors and inhibitors: Radiation response modulators
    • L. Sartor Epidermal growth factor family receptors and inhibitors: radiation response modulators Semin Radiat Oncol 1 2003 22 30
    • (2003) Semin Radiat Oncol , vol.1 , pp. 22-30
    • Sartor, L.1
  • 147
    • 0033966576 scopus 로고    scopus 로고
    • In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody
    • L. Milas, K. Mason, and N. Hunter In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody Clin Cancer Res 6 2000 701 708
    • (2000) Clin Cancer Res , vol.6 , pp. 701-708
    • Milas, L.1    Mason, K.2    Hunter, N.3
  • 148
    • 16244400108 scopus 로고    scopus 로고
    • Cetuximab: An epidermal growth factor receptor chimeric human-murine monoclonal antibody
    • J. Harding, and B. Burtness Cetuximab: an epidermal growth factor receptor chimeric human-murine monoclonal antibody Drugs Today (Barc) 41 2005 107 127
    • (2005) Drugs Today (Barc) , vol.41 , pp. 107-127
    • Harding, J.1    Burtness, B.2
  • 150
    • 8644219632 scopus 로고    scopus 로고
    • Clinical activity of farnesyl transferase inhibitors in hematologic malignancies: Possible mechanisms of action
    • E. Jabbour, H. Kantarjian, and J. Cortes Clinical activity of farnesyl transferase inhibitors in hematologic malignancies: possible mechanisms of action Leuk Lymphoma 45 2004 2187 2195
    • (2004) Leuk Lymphoma , vol.45 , pp. 2187-2195
    • Jabbour, E.1    Kantarjian, H.2    Cortes, J.3
  • 151
    • 0035283895 scopus 로고    scopus 로고
    • Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228
    • G.P. Prevost, A. Pradines, and M.C. Brezak Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228 Int J Cancer 91 2001 718 722
    • (2001) Int J Cancer , vol.91 , pp. 718-722
    • Prevost, G.P.1    Pradines, A.2    Brezak, M.C.3
  • 152
    • 0026452858 scopus 로고
    • Ionizing radiation activates transcription of the EGR1 gene via CArG elements
    • R. Datta, E. Rubin, and V. Sukhatme Ionizing radiation activates transcription of the EGR1 gene via CArG elements Proc Natl Acad Sci USA 89 1992 10149 10153
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10149-10153
    • Datta, R.1    Rubin, E.2    Sukhatme, V.3
  • 153
    • 0029159918 scopus 로고
    • Spatial and temporal control of gene therapy using ionizing radiation
    • D.E. Hallahan, H.J. Mauceri, and L.P. Seung Spatial and temporal control of gene therapy using ionizing radiation Nat Med 1 1995 786 791
    • (1995) Nat Med , vol.1 , pp. 786-791
    • Hallahan, D.E.1    Mauceri, H.J.2    Seung, L.P.3
  • 154
    • 0028809584 scopus 로고
    • Genetic radiotherapy overcomes tumor resistance to cytotoxic agents
    • L.P. Seung, H.J. Mauceri, and M.A. Beckett Genetic radiotherapy overcomes tumor resistance to cytotoxic agents Cancer Res 55 1995 5561 5565
    • (1995) Cancer Res , vol.55 , pp. 5561-5565
    • Seung, L.P.1    Mauceri, H.J.2    Beckett, M.A.3
  • 155
    • 0036845222 scopus 로고    scopus 로고
    • Radiation-induced tumour necrosis factor-alpha expression: Clinical application of transcriptional and physical targeting of gene therapy
    • R.R. Weichselbaum, D.W. Kufe, and S. Hellman Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy Lancet Oncol 3 2002 665 671
    • (2002) Lancet Oncol , vol.3 , pp. 665-671
    • Weichselbaum, R.R.1    Kufe, D.W.2    Hellman, S.3
  • 156
    • 0023280093 scopus 로고
    • Therapeutic potential of tumor necrosis factor-alpha and gamma-interferon in experimental human ovarian cancer
    • F.R. Balkwill, B.G. Ward, and E. Moodie Therapeutic potential of tumor necrosis factor-alpha and gamma-interferon in experimental human ovarian cancer Cancer Res 47 1987 4755 4758
    • (1987) Cancer Res , vol.47 , pp. 4755-4758
    • Balkwill, F.R.1    Ward, B.G.2    Moodie, E.3
  • 157
    • 0023130601 scopus 로고
    • Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo
    • A. Asher, J.J. Mule, and C.M. Reichert Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo J Immunol 138 1987 963 974
    • (1987) J Immunol , vol.138 , pp. 963-974
    • Asher, A.1    Mule, J.J.2    Reichert, C.M.3
  • 158
    • 0023038367 scopus 로고
    • Cures and partial regression of murine and human tumors by recombinant human tumor necrosis factor
    • A.A. Creasey, M.T. Reynolds, and W. Laird Cures and partial regression of murine and human tumors by recombinant human tumor necrosis factor Cancer Res 46 1986 5687 5690
    • (1986) Cancer Res , vol.46 , pp. 5687-5690
    • Creasey, A.A.1    Reynolds, M.T.2    Laird, W.3
  • 159
    • 0028840528 scopus 로고
    • Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: Effect of tumor type, transplantation site, and host strain
    • D. Fukumura, H.A. Salehi, and B. Witwer Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain Cancer Res 55 1995 4824 4829
    • (1995) Cancer Res , vol.55 , pp. 4824-4829
    • Fukumura, D.1    Salehi, H.A.2    Witwer, B.3
  • 160
    • 0029777311 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature
    • H.J. Mauceri, N.N. Hanna, and J.D. Wayne Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature Cancer Res 56 1996 4311 4314
    • (1996) Cancer Res , vol.56 , pp. 4311-4314
    • Mauceri, H.J.1    Hanna, N.N.2    Wayne, J.D.3
  • 161
    • 0032199393 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer
    • T.D. Chung, H.J. Mauceri, and D.E. Hallahan Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer Cancer Gene Ther 5 1998 344 349
    • (1998) Cancer Gene Ther , vol.5 , pp. 344-349
    • Chung, T.D.1    Mauceri, H.J.2    Hallahan, D.E.3
  • 162
    • 0031951530 scopus 로고    scopus 로고
    • Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft
    • M.J. Staba, H.J. Mauceri, and D.W. Kufe Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft Gene Ther 5 1998 293 300
    • (1998) Gene Ther , vol.5 , pp. 293-300
    • Staba, M.J.1    Mauceri, H.J.2    Kufe, D.W.3
  • 163
    • 0036279829 scopus 로고    scopus 로고
    • Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma
    • V.K. Gupta, J.O. Park, and N.T. Jaskowiak Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma Ann Surg Oncol 9 2002 500 504
    • (2002) Ann Surg Oncol , vol.9 , pp. 500-504
    • Gupta, V.K.1    Park, J.O.2    Jaskowiak, N.T.3
  • 164
    • 0000546442 scopus 로고
    • Phase I dose-escalation study of tumor necrosis factor-alpha and concomitant radiation therapy
    • D.E. Hallahan, E.E. Vokes, and S.J. Rubin Phase I dose-escalation study of tumor necrosis factor-alpha and concomitant radiation therapy Cancer J Sci Am 1 1995 204
    • (1995) Cancer J Sci Am , vol.1 , pp. 204
    • Hallahan, D.E.1    Vokes, E.E.2    Rubin, S.J.3
  • 165
    • 0033190968 scopus 로고    scopus 로고
    • A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor alpha expressed from an adenovirus vector induces an antitumor response with reduced toxicity
    • R.A. Marr, M. Hitt, and J. Gauldie A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor alpha expressed from an adenovirus vector induces an antitumor response with reduced toxicity Cancer Gene Ther 6 1999 465 4674
    • (1999) Cancer Gene Ther , vol.6 , pp. 465-4674
    • Marr, R.A.1    Hitt, M.2    Gauldie, J.3
  • 166
    • 0031908236 scopus 로고    scopus 로고
    • Tumour therapy in mice using adenovirus vectors expressing human TNFa
    • R.A. Marr, M. Hitt, and W.J. Muller Tumour therapy in mice using adenovirus vectors expressing human TNFa Int J Oncol 12 1998 509 515
    • (1998) Int J Oncol , vol.12 , pp. 509-515
    • Marr, R.A.1    Hitt, M.2    Muller, W.J.3
  • 167
    • 4444295881 scopus 로고    scopus 로고
    • A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities
    • A.J. Mundt, S. Vijayakumar, and J. Nemunaitis A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities Clin Cancer Res 10 2004 5747 5753
    • (2004) Clin Cancer Res , vol.10 , pp. 5747-5753
    • Mundt, A.J.1    Vijayakumar, S.2    Nemunaitis, J.3
  • 168
    • 0025799563 scopus 로고
    • Phase I trial of recombinant human tumour necrosis factor alpha in patients with advanced malignancy
    • H. Gamm, A. Lindemann, and R. Mertelsmann Phase I trial of recombinant human tumour necrosis factor alpha in patients with advanced malignancy Eur J Cancer 27 1991 856 863
    • (1991) Eur J Cancer , vol.27 , pp. 856-863
    • Gamm, H.1    Lindemann, A.2    Mertelsmann, R.3
  • 169
    • 1442332187 scopus 로고    scopus 로고
    • TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: A phase I study in patients with solid tumors
    • N. Senzer, S. Mani, and A. Rosemurgy TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors J Clin Oncol 22 2004 592 601
    • (2004) J Clin Oncol , vol.22 , pp. 592-601
    • Senzer, N.1    Mani, S.2    Rosemurgy, A.3
  • 170
    • 25144471132 scopus 로고    scopus 로고
    • TNFerade, an adenovector carrying the transgene for human tumor necrosis factor alpha, for patients with advanced solid tumors: Surgical experience and long-term follow-up
    • J.M. McLoughlin, T.M. McCarty, and C. Cunningham TNFerade, an adenovector carrying the transgene for human tumor necrosis factor alpha, for patients with advanced solid tumors: surgical experience and long-term follow-up Ann Surg Oncol 12 2005 825 830
    • (2005) Ann Surg Oncol , vol.12 , pp. 825-830
    • McLoughlin, J.M.1    McCarty, T.M.2    Cunningham, C.3
  • 171
    • 0002487481 scopus 로고
    • Hyperthermia
    • 4th edition Lippincott, Williams & Wilkins
    • E.J. Hall Hyperthermia Radiobiology for the radiologist 4th edition 1994 Lippincott, Williams & Wilkins 257 288
    • (1994) Radiobiology for the Radiologist , pp. 257-288
    • Hall, E.J.1
  • 172
    • 0038376295 scopus 로고    scopus 로고
    • Cellular effects of hyperthermia: Relevance to the minimum dose for thermal damage
    • J.R. Lepock Cellular effects of hyperthermia: relevance to the minimum dose for thermal damage Int J Hyperthermia 19 2003 252 266
    • (2003) Int J Hyperthermia , vol.19 , pp. 252-266
    • Lepock, J.R.1
  • 173
    • 0025297191 scopus 로고
    • Relationship of changes in pH and energy status to hypoxic cell fraction and hyperthermia sensitivity
    • J.A. Koutcher, D. Barnett, and A.B. Kornblith Relationship of changes in pH and energy status to hypoxic cell fraction and hyperthermia sensitivity Int J Radiat Oncol Biol Phys 18 1990 1429 1435
    • (1990) Int J Radiat Oncol Biol Phys , vol.18 , pp. 1429-1435
    • Koutcher, J.A.1    Barnett, D.2    Kornblith, A.B.3
  • 175
    • 0026131592 scopus 로고
    • Combining hyperthermia and radiation: How beneficial?
    • P.K. Sneed, and T.L. Phillips Combining hyperthermia and radiation: how beneficial? Oncology (Williston Park) 5 1991 99 108 [discussion: 109-10, 112]
    • (1991) Oncology (Williston Park) , vol.5 , pp. 99-108
    • Sneed, P.K.1    Phillips, T.L.2
  • 176
    • 0030200474 scopus 로고    scopus 로고
    • Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: Results from five randomized controlled trials. International Collaborative Hyperthermia Group
    • C.C. Vernon, J.W. Hand, and S.B. Field Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. International Collaborative Hyperthermia Group Int J Radiat Oncol Biol Phys 35 1996 731 744
    • (1996) Int J Radiat Oncol Biol Phys , vol.35 , pp. 731-744
    • Vernon, C.C.1    Hand, J.W.2    Field, S.B.3
  • 177
    • 0028934336 scopus 로고
    • Randomised trial of hyperthermia as adjuvant to radiotherapy for recurrent or metastatic malignant melanoma. European Society for Hyperthermic Oncology
    • J. Overgaard, D. Gonzalez Gonzalez, and M.C. Hulshof Randomised trial of hyperthermia as adjuvant to radiotherapy for recurrent or metastatic malignant melanoma. European Society for Hyperthermic Oncology Lancet 345 1995 540 543
    • (1995) Lancet , vol.345 , pp. 540-543
    • Overgaard, J.1    Gonzalez Gonzalez, D.2    Hulshof, M.C.3
  • 178
    • 0028054799 scopus 로고
    • Report of long-term follow-up in a randomized trial comparing radiation therapy and radiation therapy plus hyperthermia to metastatic lymph nodes in stage IV head and neck patients
    • R. Valdagni, and M. Amichetti Report of long-term follow-up in a randomized trial comparing radiation therapy and radiation therapy plus hyperthermia to metastatic lymph nodes in stage IV head and neck patients Int J Radiat Oncol Biol Phys 28 1994 163 169
    • (1994) Int J Radiat Oncol Biol Phys , vol.28 , pp. 163-169
    • Valdagni, R.1    Amichetti, M.2
  • 179
    • 0025358746 scopus 로고
    • Head and neck cancers: Results of thermoradiotherapy versus radiotherapy
    • N.R. Datta, A.K. Bose, and H.K. Kapoor Head and neck cancers: results of thermoradiotherapy versus radiotherapy Int J Hyperthermia 6 1990 479 486
    • (1990) Int J Hyperthermia , vol.6 , pp. 479-486
    • Datta, N.R.1    Bose, A.K.2    Kapoor, H.K.3
  • 180
    • 0342545492 scopus 로고    scopus 로고
    • Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: A prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group
    • J. van der Zee, D. Gonzalez Gonzalez, and G.C. van Rhoon Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group Lancet 355 2000 1119 1125
    • (2000) Lancet , vol.355 , pp. 1119-1125
    • Van Der Zee, J.1    Gonzalez Gonzalez, D.2    Van Rhoon, G.C.3
  • 181
    • 0035113848 scopus 로고    scopus 로고
    • A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma
    • Y. Harima, K. Nagata, and K. Harima A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma Int J Hyperthermia 17 2001 97 105
    • (2001) Int J Hyperthermia , vol.17 , pp. 97-105
    • Harima, Y.1    Nagata, K.2    Harima, K.3
  • 182
    • 0025216470 scopus 로고
    • Side-effects of local hyperthermia: Results of a prospectively randomized clinical study
    • S. Sharma, A.P. Sandhu, and F.D. Patel Side-effects of local hyperthermia: results of a prospectively randomized clinical study Int J Hyperthermia 6 1990 279 285
    • (1990) Int J Hyperthermia , vol.6 , pp. 279-285
    • Sharma, S.1    Sandhu, A.P.2    Patel, F.D.3
  • 183
    • 0004098764 scopus 로고    scopus 로고
    • Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost ±hyperthermia for glioblastoma multiforme
    • P.K. Sneed, P.R. Stauffer, and M.W. McDermott Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost ±hyperthermia for glioblastoma multiforme Int J Radiat Oncol Biol Phys 40 1998 287 295
    • (1998) Int J Radiat Oncol Biol Phys , vol.40 , pp. 287-295
    • Sneed, P.K.1    Stauffer, P.R.2    McDermott, M.W.3
  • 184
    • 19644369686 scopus 로고    scopus 로고
    • Randomized trial of hyperthermia and radiation for superficial tumors
    • E.L. Jones, J.R. Oleson, and L.R. Prosnitz Randomized trial of hyperthermia and radiation for superficial tumors J Clin Oncol 23 2005 3079 3085
    • (2005) J Clin Oncol , vol.23 , pp. 3079-3085
    • Jones, E.L.1    Oleson, J.R.2    Prosnitz, L.R.3
  • 185
    • 0022633947 scopus 로고
    • Kinetics of thermotolerance in normal and tumor tissues: A review
    • M. Urano Kinetics of thermotolerance in normal and tumor tissues: a review Cancer Res 46 1986 474 482
    • (1986) Cancer Res , vol.46 , pp. 474-482
    • Urano, M.1
  • 186
    • 0034305965 scopus 로고    scopus 로고
    • Phase III randomized trial of amifostine as a radioprotector in head and neck cancer
    • D.M. Brizel, T.H. Wasserman, and M. Henke Phase III randomized trial of amifostine as a radioprotector in head and neck cancer J Clin Oncol 18 2000 3339 3345
    • (2000) J Clin Oncol , vol.18 , pp. 3339-3345
    • Brizel, D.M.1    Wasserman, T.H.2    Henke, M.3
  • 187
    • 1642558247 scopus 로고    scopus 로고
    • Amifostine: Is there evidence of tumor protection?
    • M.I. Koukourakis Amifostine: is there evidence of tumor protection? Semin Oncol 30 2003 18 30
    • (2003) Semin Oncol , vol.30 , pp. 18-30
    • Koukourakis, M.I.1
  • 188
    • 0028069933 scopus 로고
    • Preliminary results of a pilot study using WR-2721 before fractionated irradiation of the head and neck to reduce salivary gland dysfunction
    • S. McDonald, C. Meyerowitz, and T. Smudzin Preliminary results of a pilot study using WR-2721 before fractionated irradiation of the head and neck to reduce salivary gland dysfunction Int J Radiat Oncol Biol Phys 29 1994 747 754
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , pp. 747-754
    • McDonald, S.1    Meyerowitz, C.2    Smudzin, T.3
  • 189
    • 0345148941 scopus 로고    scopus 로고
    • Amifostine-a radioprotector in locally advanced head and neck tumors
    • K.G. Schonekas, W. Wagner, and F.J. Prott Amifostine-a radioprotector in locally advanced head and neck tumors Strahlentherapie und Onkologie 175 Suppl 4 1999 27 29
    • (1999) Strahlentherapie und Onkologie , vol.175 , Issue.SUPPL. 4 , pp. 27-29
    • Schonekas, K.G.1    Wagner, W.2    Prott, F.J.3
  • 190
    • 0036498533 scopus 로고    scopus 로고
    • Prophylactic use of amifostine to prevent radiochemotherapy-induced mucositis and xerostomia in head-and-neck cancer
    • D. Antonadou, M. Pepelassi, and M. Synodinou Prophylactic use of amifostine to prevent radiochemotherapy-induced mucositis and xerostomia in head-and-neck cancer Int J Radiat Oncol Biol Phys 52 2002 739 747
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , pp. 739-747
    • Antonadou, D.1    Pepelassi, M.2    Synodinou, M.3
  • 191
    • 16344389534 scopus 로고    scopus 로고
    • Chemotherapy- and radiotherapy-induced oral mucositis: Review of preventive strategies and treatment
    • C.E. Saadeh Chemotherapy- and radiotherapy-induced oral mucositis: review of preventive strategies and treatment Pharmacotherapy 25 2005 540 554
    • (2005) Pharmacotherapy , vol.25 , pp. 540-554
    • Saadeh, C.E.1
  • 192
    • 0037456708 scopus 로고    scopus 로고
    • Oral administration is as effective as intraperitoneal administration of amifostine in decreasing nitroxide EPR signal decay in vivo
    • M. Elas, A. Parasca, and D.J. Grdina Oral administration is as effective as intraperitoneal administration of amifostine in decreasing nitroxide EPR signal decay in vivo Biochim Biophys Acta 1637 2003 151 155
    • (2003) Biochim Biophys Acta , vol.1637 , pp. 151-155
    • Elas, M.1    Parasca, A.2    Grdina, D.J.3
  • 193
    • 0036984990 scopus 로고    scopus 로고
    • Preliminary data of the GORTEC 2000-02 phase III trial comparing intravenous and subcutaneous administration of amifostine for head and neck tumors treated by external radiotherapy
    • E. Bardet, L. Martin, and G. Calais Preliminary data of the GORTEC 2000-02 phase III trial comparing intravenous and subcutaneous administration of amifostine for head and neck tumors treated by external radiotherapy Semin Oncol 29 2002 57 60
    • (2002) Semin Oncol , vol.29 , pp. 57-60
    • Bardet, E.1    Martin, L.2    Calais, G.3
  • 194
    • 0036985748 scopus 로고    scopus 로고
    • Phase II trial of subcutaneous amifostine in patients undergoing radiation therapy for head and neck cancer
    • P.R. Anne Phase II trial of subcutaneous amifostine in patients undergoing radiation therapy for head and neck cancer Semin Oncol 29 2002 80 83
    • (2002) Semin Oncol , vol.29 , pp. 80-83
    • Anne, P.R.1
  • 195
    • 21044438035 scopus 로고    scopus 로고
    • Phase II multicenter randomized study of amifostine for prevention of acute radiation rectal toxicity: Topical intrarectal versus subcutaneous application
    • V.E. Kouloulias, J.R. Kouvaris, and G. Pissakas Phase II multicenter randomized study of amifostine for prevention of acute radiation rectal toxicity: topical intrarectal versus subcutaneous application Int J Radiat Oncol Biol Phys 62 2005 486 493
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , pp. 486-493
    • Kouloulias, V.E.1    Kouvaris, J.R.2    Pissakas, G.3
  • 196
    • 0036680335 scopus 로고    scopus 로고
    • A pilot study of topical intrarectal application of amifostine for prevention of late radiation rectal injury
    • E. Ben-Josef, S. Han, and M. Tobi A pilot study of topical intrarectal application of amifostine for prevention of late radiation rectal injury Int J Radiat Oncol Biol Phys 53 2002 1160 1164
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 1160-1164
    • Ben-Josef, E.1    Han, S.2    Tobi, M.3
  • 197
    • 4544342406 scopus 로고    scopus 로고
    • A phase II randomized study of topical intrarectal administration of amifostine for the prevention of acute radiation-induced rectal toxicity
    • V.E. Kouloulias, J.R. Kouvaris, and G. Pissakas A phase II randomized study of topical intrarectal administration of amifostine for the prevention of acute radiation-induced rectal toxicity Strahlentherapie und Onkologie 180 2004 557 562
    • (2004) Strahlentherapie und Onkologie , vol.180 , pp. 557-562
    • Kouloulias, V.E.1    Kouvaris, J.R.2    Pissakas, G.3
  • 198
    • 1642517270 scopus 로고    scopus 로고
    • Clinical trial of endorectal amifostine for radioprotection in patients with prostate cancer: Rationale and early results
    • C. Menard, K. Camphausen, and T. Muanza Clinical trial of endorectal amifostine for radioprotection in patients with prostate cancer: rationale and early results Semin Oncol 30 2003 63 67
    • (2003) Semin Oncol , vol.30 , pp. 63-67
    • Menard, C.1    Camphausen, K.2    Muanza, T.3
  • 199
    • 3042651070 scopus 로고    scopus 로고
    • Impact on cytoprotective efficacy of intermediate interval between amifostine administration and radiotherapy: A retrospective analysis
    • V.E. Kouloulias, J.R. Kouvaris, and J.D. Kokakis Impact on cytoprotective efficacy of intermediate interval between amifostine administration and radiotherapy: a retrospective analysis Int J Radiat Oncol Biol Phys 59 2004 1148 1156
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 1148-1156
    • Kouloulias, V.E.1    Kouvaris, J.R.2    Kokakis, J.D.3
  • 200
    • 15544368334 scopus 로고    scopus 로고
    • A randomized phase II study of paclitaxel with carboplatin ±amifostine as first line treatment in advanced ovarian carcinoma
    • F.Y. De Vos, A.M. Bos, and M. Schaapveld A randomized phase II study of paclitaxel with carboplatin ±amifostine as first line treatment in advanced ovarian carcinoma Gynecol Oncol 97 2005 60 67
    • (2005) Gynecol Oncol , vol.97 , pp. 60-67
    • De Vos, F.Y.1    Bos, A.M.2    Schaapveld, M.3
  • 201
    • 0024949320 scopus 로고
    • Nature of the enhancement of the protective qualities of gastric mucus by sucralfate
    • B.L. Slomiany, J. Piotrowski, and K. Okazaki Nature of the enhancement of the protective qualities of gastric mucus by sucralfate Digestion 44 1989 222 231
    • (1989) Digestion , vol.44 , pp. 222-231
    • Slomiany, B.L.1    Piotrowski, J.2    Okazaki, K.3
  • 202
    • 13644273530 scopus 로고
    • Mechanisms of gastroduodenal protection by sucralfate
    • W.D. Rees Mechanisms of gastroduodenal protection by sucralfate Am J Med 91 1991 58S 63S
    • (1991) Am J Med , vol.91
    • Rees, W.D.1
  • 203
    • 0026048523 scopus 로고
    • Comparison of sucralfate and ranitidine in the treatment of duodenal ulcers
    • J. Garcia-Paredes, M. Diaz Rubio, and F. Llenas Comparison of sucralfate and ranitidine in the treatment of duodenal ulcers Am J Med 91 1991 64S 67S
    • (1991) Am J Med , vol.91
    • Garcia-Paredes, J.1    Diaz Rubio, M.2    Llenas, F.3
  • 204
    • 0036805256 scopus 로고    scopus 로고
    • Comparison of granulocyte-macrophage colony-stimulating factor and sucralfate mouthwashes in the prevention of radiation-induced mucositis: A double-blind prospective randomized phase III study
    • K. Saarilahti, M. Kajanti, and T. Joensuu Comparison of granulocyte-macrophage colony-stimulating factor and sucralfate mouthwashes in the prevention of radiation-induced mucositis: a double-blind prospective randomized phase III study Int J Radiat Oncol Biol Phys 54 2002 479 485
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 479-485
    • Saarilahti, K.1    Kajanti, M.2    Joensuu, T.3
  • 205
    • 0026766751 scopus 로고
    • Effects of sucralfate on acute and late bowel discomfort following radiotherapy of pelvic cancer
    • R. Henriksson, L. Franzen, and B. Littbrand Effects of sucralfate on acute and late bowel discomfort following radiotherapy of pelvic cancer J Clin Oncol 10 1992 969 975
    • (1992) J Clin Oncol , vol.10 , pp. 969-975
    • Henriksson, R.1    Franzen, L.2    Littbrand, B.3
  • 207
    • 0036804604 scopus 로고    scopus 로고
    • Acute symptoms, not rectally administered sucralfate, predict for late radiation proctitis: Longer term follow-up of a phase III trial-Trans-Tasman Radiation Oncology Group
    • P.C. O'Brien, C.I. Franklin, and M.G. Poulsen Acute symptoms, not rectally administered sucralfate, predict for late radiation proctitis: longer term follow-up of a phase III trial-Trans-Tasman Radiation Oncology Group Int J Radiat Oncol Biol Phys 54 2002 442 449
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 442-449
    • O'Brien, P.C.1    Franklin, C.I.2    Poulsen, M.G.3
  • 208
    • 0034021855 scopus 로고    scopus 로고
    • Sucralfate in the prevention of treatment-induced diarrhea in patients receiving pelvic radiation therapy: A North Central Cancer Treatment Group phase III double-blind placebo-controlled trial
    • J.A. Martenson, J.W. Bollinger, and J.A. Sloan Sucralfate in the prevention of treatment-induced diarrhea in patients receiving pelvic radiation therapy: a North Central Cancer Treatment Group phase III double-blind placebo-controlled trial J Clin Oncol 18 2000 1239 1245
    • (2000) J Clin Oncol , vol.18 , pp. 1239-1245
    • Martenson, J.A.1    Bollinger, J.W.2    Sloan, J.A.3
  • 209
    • 3242688111 scopus 로고    scopus 로고
    • Augmentation of wound healing by ascorbic acid treatment in mice exposed to gamma-radiation
    • G.C. Jagetia, G.K. Rajanikant, and M.S. Baliga Augmentation of wound healing by ascorbic acid treatment in mice exposed to gamma-radiation Int J Radiat Biol 80 2004 347 354
    • (2004) Int J Radiat Biol , vol.80 , pp. 347-354
    • Jagetia, G.C.1    Rajanikant, G.K.2    Baliga, M.S.3
  • 210
    • 22444451354 scopus 로고    scopus 로고
    • Phase II study of vitamin e and pentoxifylline in patients with late side effects of pelvic radiotherapy
    • L. Gothard, P. Cornes, and S. Brooker Phase II study of vitamin E and pentoxifylline in patients with late side effects of pelvic radiotherapy Radiother Oncol 75 2005 334 341
    • (2005) Radiother Oncol , vol.75 , pp. 334-341
    • Gothard, L.1    Cornes, P.2    Brooker, S.3
  • 211
    • 0027512264 scopus 로고
    • Vitamin C as a radioprotector against iodine-131 in vivo
    • V.R. Narra, R.W. Howell, and K.S. Sastry Vitamin C as a radioprotector against iodine-131 in vivo J Nucl Med 34 1993 637 640
    • (1993) J Nucl Med , vol.34 , pp. 637-640
    • Narra, V.R.1    Howell, R.W.2    Sastry, K.S.3
  • 212
    • 0035140395 scopus 로고    scopus 로고
    • Thyroid carcinoma usually occurs in patients with familial adenomatous polyposis in the absence of biallelic inactivation of the adenomatous polyposis coli gene
    • F. Cetta, M.C. Curia, and G. Montalto Thyroid carcinoma usually occurs in patients with familial adenomatous polyposis in the absence of biallelic inactivation of the adenomatous polyposis coli gene J Clin Endocrinol Metab 86 2001 427 432
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 427-432
    • Cetta, F.1    Curia, M.C.2    Montalto, G.3
  • 213
    • 18044390672 scopus 로고    scopus 로고
    • Effect of tocopherol-monoglucoside (TMG), a water-soluble glycosylated derivate of vitamin E, on hematopoietic recovery in irradiated mice
    • N. Cherdyntseva, A. Shishkina, and I. Butorin Effect of tocopherol-monoglucoside (TMG), a water-soluble glycosylated derivate of vitamin E, on hematopoietic recovery in irradiated mice J Radiat Res (Tokyo) 46 2005 37 41
    • (2005) J Radiat Res (Tokyo) , vol.46 , pp. 37-41
    • Cherdyntseva, N.1    Shishkina, A.2    Butorin, I.3
  • 214
    • 0036286713 scopus 로고    scopus 로고
    • Uterine restoration by radiation sequelae regression with combined pentoxifylline-tocopherol: A phase II study
    • H. Letur-Konirsch, F. Guis, and S. Delanian Uterine restoration by radiation sequelae regression with combined pentoxifylline-tocopherol: a phase II study Fertil Steril 77 2002 1219 1226
    • (2002) Fertil Steril , vol.77 , pp. 1219-1226
    • Letur-Konirsch, H.1    Guis, F.2    Delanian, S.3
  • 215
    • 0038352140 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis
    • S. Delanian, R. Porcher, and S. Balla-Mekias Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis J Clin Oncol 21 2003 2545 2550
    • (2003) J Clin Oncol , vol.21 , pp. 2545-2550
    • Delanian, S.1    Porcher, R.2    Balla-Mekias, S.3
  • 216
    • 24944500925 scopus 로고    scopus 로고
    • Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients
    • I. Bairati, F. Meyer, and M. Gelinas Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients J Clin Oncol 23 2005 5805 5813
    • (2005) J Clin Oncol , vol.23 , pp. 5805-5813
    • Bairati, I.1    Meyer, F.2    Gelinas, M.3
  • 217
    • 21844435999 scopus 로고    scopus 로고
    • Effects of various vitamins and coenzymes Q on reactions involving alpha-hydroxyl-containing radicals
    • O.I. Shadyro, A.A. Sosnovskaya, and I.P. Edimecheva Effects of various vitamins and coenzymes Q on reactions involving alpha-hydroxyl-containing radicals Free Radic Res 39 2005 713 718
    • (2005) Free Radic Res , vol.39 , pp. 713-718
    • Shadyro, O.I.1    Sosnovskaya, A.A.2    Edimecheva, I.P.3
  • 218
    • 0024804118 scopus 로고
    • Treatment of radiation side effects with oral pilocarpine
    • D.E. Schuller, P. Stevens, and K.P. Clausen Treatment of radiation side effects with oral pilocarpine J Surg Oncol 42 1989 272 276
    • (1989) J Surg Oncol , vol.42 , pp. 272-276
    • Schuller, D.E.1    Stevens, P.2    Clausen, K.P.3
  • 219
    • 0027273213 scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled, dose-titration study of oral pilocarpine for treatment of radiation-induced xerostomia in head and neck cancer patients
    • F.G. LeVeque, M. Montgomery, and D. Potter A multicenter, randomized, double-blind, placebo-controlled, dose-titration study of oral pilocarpine for treatment of radiation-induced xerostomia in head and neck cancer patients J Clin Oncol 11 1993 1124 1131
    • (1993) J Clin Oncol , vol.11 , pp. 1124-1131
    • Leveque, F.G.1    Montgomery, M.2    Potter, D.3
  • 220
    • 0036661290 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of concomitant pilocarpine with head and neck irradiation for prevention of radiation-induced xerostomia
    • P. Haddad, and M. Karimi A randomized, double-blind, placebo-controlled trial of concomitant pilocarpine with head and neck irradiation for prevention of radiation-induced xerostomia Radiother Oncol 64 2002 29 32
    • (2002) Radiother Oncol , vol.64 , pp. 29-32
    • Haddad, P.1    Karimi, M.2
  • 221
    • 0028857470 scopus 로고
    • Oral pilocarpine for radiation-induced xerostomia: Integrated efficacy and safety results from two prospective randomized clinical trials
    • J.W. Rieke, M.D. Hafermann, and J.T. Johnson Oral pilocarpine for radiation-induced xerostomia: integrated efficacy and safety results from two prospective randomized clinical trials Int J Radiat Oncol Biol Phys 31 1995 661 669
    • (1995) Int J Radiat Oncol Biol Phys , vol.31 , pp. 661-669
    • Rieke, J.W.1    Hafermann, M.D.2    Johnson, J.T.3
  • 222
    • 0036719973 scopus 로고    scopus 로고
    • A Phase III placebo-controlled trial of oral pilocarpine in patients undergoing radiotherapy for head-and-neck cancer
    • P. Warde, B. O'Sullivan, and J. Aslanidis A Phase III placebo-controlled trial of oral pilocarpine in patients undergoing radiotherapy for head-and-neck cancer Int J Radiat Oncol Biol Phys 54 2002 9 13
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 9-13
    • Warde, P.1    O'Sullivan, B.2    Aslanidis, J.3
  • 223
    • 3242715690 scopus 로고    scopus 로고
    • Double-blind randomized, placebo-controlled study of pilocarpine to salvage salivary gland function during radiotherapy of patients with head and neck cancer
    • M. Gornitsky, G. Shenouda, and K. Sultanem Double-blind randomized, placebo-controlled study of pilocarpine to salvage salivary gland function during radiotherapy of patients with head and neck cancer Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98 2004 45 52
    • (2004) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.98 , pp. 45-52
    • Gornitsky, M.1    Shenouda, G.2    Sultanem, K.3
  • 224
    • 0037605893 scopus 로고    scopus 로고
    • Phase III quality-of-life study results: Impact on patients' quality of life to reducing xerostomia after radiotherapy for head-and-neck cancer-RTOG 97-09
    • J. Fisher, C. Scott, and C.W. Scarantino Phase III quality-of-life study results: impact on patients' quality of life to reducing xerostomia after radiotherapy for head-and-neck cancer-RTOG 97-09 Int J Radiat Oncol Biol Phys 56 2003 832 836
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 832-836
    • Fisher, J.1    Scott, C.2    Scarantino, C.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.