Measurement of delivery and metabolism of tirapazamine to tumour tissue using the multilayered cell culture model

Cancer Chemotherapy and Pharmacology

Volumn 43, Issue 3, 1999, Pages 213-220

  Kyle, Alastair H ^a   Minchinton, Andrew I ^a  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

Author keywords

Drug delivery; Drug diffusion penetration; Multilayered cell culture; Tirapazamine; Tumour modelling

Indexed keywords

CYTOTOXIN; SR 259075; TIRAPAZAMINE; TRIAZONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; CELL KILLING; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG METABOLISM; DRUG PENETRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOXIC CELL; MATHEMATICAL MODEL; NONHUMAN; OXYGEN TENSION; PRIORITY JOURNAL; TUMOR CELL CULTURE;

ALGORITHMS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFUSION; FEMALE; HUMANS; MEMBRANES, ARTIFICIAL; MODELS, BIOLOGICAL; POLYTETRAFLUOROETHYLENE; TISSUE DISTRIBUTION; TRIAZINES; TUMOR CELLS, CULTURED; UTERINE CERVICAL NEOPLASMS;

EID: 0032917763     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050886     Document Type: Article

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