Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species

International Journal of Radiation Oncology Biology Physics

Volumn 51, Issue 4, 2001, Pages 1025-1036

  Magda, Darren ^a   Lepp, Cheryl ^a   Gerasimchuk, Nikolay ^a   Lee, Intae ^a   Sessler, Jonathan L ^b   Lin, Alice ^a   Biaglow, John E ^c   Miller, Richard A ^a  

^a PHARMACYCLICS INC   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Ascorbate; Radiation; Sensitizer; Superoxide; Texaphyrin

Indexed keywords

CELL CULTURE; DRUG PRODUCTS; DYES; ENZYMES; HYDROGEN PEROXIDE; OXIDATION; RADIATION;

APOPTOSIS-SENSITIVE-B-CELL LINES;

ONCOLOGY;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ASCORBIC ACID; GADOLINIUM TEXAPHYRIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIZING RADIATION; LUNG CARCINOMA; LYMPHOMA CELL LINE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RADIATION RESPONSE; RADIOSENSITIZATION; TUMOR CELL LINE; UTERUS CANCER;

ANIMALS; ANTINEOPLASTIC AGENTS; ASCORBIC ACID; CHO CELLS; CRICETINAE; FEMALE; HUMANS; HYDROGEN PEROXIDE; METALLOPORPHYRINS; NADP; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED; UTERINE NEOPLASMS;

EID: 0035889348     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(01)01810-7     Document Type: Article

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