-
1
-
-
6044230603
-
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells
-
Akbari M., Otterlei M., Pena-Diaz J., Aas P.A., Kavli B., Liabakk N.B., Hagen L., Imai K., Durandy A., Slupphaug G., and Krokan H.E. Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells. Nucleic Acids Res. 32 (2004) 5486-5498
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 5486-5498
-
-
Akbari, M.1
Otterlei, M.2
Pena-Diaz, J.3
Aas, P.A.4
Kavli, B.5
Liabakk, N.B.6
Hagen, L.7
Imai, K.8
Durandy, A.9
Slupphaug, G.10
Krokan, H.E.11
-
2
-
-
0027414691
-
CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome
-
Allen R.C., Armitage R.J., Conley M.E., Rosenblatt H., Jenkins N.A., Copeland N.G., Bedell M.A., Edelhoff S., Disteche C.M., Simoneaux D.K., Fanslow W.C., Belmont J., et al. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science 259 (1993) 990-993
-
(1993)
Science
, vol.259
, pp. 990-993
-
-
Allen, R.C.1
Armitage, R.J.2
Conley, M.E.3
Rosenblatt, H.4
Jenkins, N.A.5
Copeland, N.G.6
Bedell, M.A.7
Edelhoff, S.8
Disteche, C.M.9
Simoneaux, D.K.10
Fanslow, W.C.11
Belmont, J.12
-
3
-
-
0034576553
-
The α/β fold uracil DNA glycosylases: A common origin with diverse fates
-
RESEARCH0007
-
Aravind L., and Koonin E.V. The α/β fold uracil DNA glycosylases: A common origin with diverse fates. Genome Biol. 1 (2000) RESEARCH0007
-
(2000)
Genome Biol.
, vol.1
-
-
Aravind, L.1
Koonin, E.V.2
-
4
-
-
0027394391
-
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome
-
Aruffo A., Farrington M., Hollenbaugh D., Li X., Milatovich A., Nonoyama S., Bajorath J., Grosmaire L.S., Stenkamp R., Neubauer M., Roberts R.L., Noelle R.J., et al. The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. Cell 72 (1993) 291-300
-
(1993)
Cell
, vol.72
, pp. 291-300
-
-
Aruffo, A.1
Farrington, M.2
Hollenbaugh, D.3
Li, X.4
Milatovich, A.5
Nonoyama, S.6
Bajorath, J.7
Grosmaire, L.S.8
Stenkamp, R.9
Neubauer, M.10
Roberts, R.L.11
Noelle, R.J.12
-
5
-
-
0035871625
-
Increased transcription levels induce higher mutation rates in a hypermutating cell line
-
Bachl J., Carlson C., Gray-Schopfer V., Dessing M., and Olsson C. Increased transcription levels induce higher mutation rates in a hypermutating cell line. J. Immunol. 166 (2001) 5051-5057
-
(2001)
J. Immunol.
, vol.166
, pp. 5051-5057
-
-
Bachl, J.1
Carlson, C.2
Gray-Schopfer, V.3
Dessing, M.4
Olsson, C.5
-
6
-
-
0141992113
-
C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion
-
Barreto V., Reina-San-Martin B., Ramiro A.R., McBride K.M., and Nussenzweig M.C. C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. Mol. Cell 12 (2003) 501-508
-
(2003)
Mol. Cell
, vol.12
, pp. 501-508
-
-
Barreto, V.1
Reina-San-Martin, B.2
Ramiro, A.R.3
McBride, K.M.4
Nussenzweig, M.C.5
-
7
-
-
28544438261
-
The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation
-
Basu U., Chaudhuri J., Alpert C., Dutt S., Ranganath S., Li G., Schrum J.P., Manis J.P., and Alt F.W. The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation. Nature 438 (2005) 508-511
-
(2005)
Nature
, vol.438
, pp. 508-511
-
-
Basu, U.1
Chaudhuri, J.2
Alpert, C.3
Dutt, S.4
Ranganath, S.5
Li, G.6
Schrum, J.P.7
Manis, J.P.8
Alt, F.W.9
-
8
-
-
4344560868
-
Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch
-
Begum N.A., Kinoshita K., Kakazu N., Muramatsu M., Nagaoka H., Shinkura R., Biniszkiewicz D., Boyer L.A., Jaenisch R., and Honjo T. Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch. Science 305 (2004) 1160-1163
-
(2004)
Science
, vol.305
, pp. 1160-1163
-
-
Begum, N.A.1
Kinoshita, K.2
Kakazu, N.3
Muramatsu, M.4
Nagaoka, H.5
Shinkura, R.6
Biniszkiewicz, D.7
Boyer, L.A.8
Jaenisch, R.9
Honjo, T.10
-
9
-
-
4444377646
-
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination
-
Begum N.A., Kinoshita K., Muramatsu M., Nagaoka H., Shinkura R., and Honjo T. De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination. Proc. Natl. Acad. Sci. USA 101 (2004) 13003-13007
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 13003-13007
-
-
Begum, N.A.1
Kinoshita, K.2
Muramatsu, M.3
Nagaoka, H.4
Shinkura, R.5
Honjo, T.6
-
10
-
-
33947313809
-
Requirement of non-canonical activity of uracil DNA glycosylase for class switch reccombination
-
Begum N.A., Izumi N., Nishikori M., Nagaoka H., Shinkura R., and Honjo T. Requirement of non-canonical activity of uracil DNA glycosylase for class switch reccombination. J. Biol. Chem. 283 (2006) 732-742
-
(2006)
J. Biol. Chem.
, vol.283
, pp. 732-742
-
-
Begum, N.A.1
Izumi, N.2
Nishikori, M.3
Nagaoka, H.4
Shinkura, R.5
Honjo, T.6
-
11
-
-
0032478787
-
Diversity of HIV-1 Vpr interactions involves usage of the WXXF motif of host cell proteins
-
BouHamdan M., Xue Y., Baudat Y., Hu B., Sire J., Pomerantz R.J., and Duan L.X. Diversity of HIV-1 Vpr interactions involves usage of the WXXF motif of host cell proteins. J. Biol. Chem. 273 (1998) 8009-8016
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8009-8016
-
-
BouHamdan, M.1
Xue, Y.2
Baudat, Y.3
Hu, B.4
Sire, J.5
Pomerantz, R.J.6
Duan, L.X.7
-
12
-
-
0037388165
-
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
-
Bransteitter R., Pham P., Scharff M.D., and Goodman M.F. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc. Natl. Acad. Sci. USA 100 (2003) 4102-4107
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4102-4107
-
-
Bransteitter, R.1
Pham, P.2
Scharff, M.D.3
Goodman, M.F.4
-
13
-
-
10944223445
-
Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase
-
Bransteitter R., Pham P., Calabrese P., and Goodman M.F. Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase. J. Biol. Chem. 279 (2004) 51612-51621
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 51612-51621
-
-
Bransteitter, R.1
Pham, P.2
Calabrese, P.3
Goodman, M.F.4
-
14
-
-
2942722486
-
Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks
-
Brar S.S., Watson M., and Diaz M. Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks. J. Biol. Chem. 279 (2004) 26395-26401
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26395-26401
-
-
Brar, S.S.1
Watson, M.2
Diaz, M.3
-
15
-
-
0037029663
-
DNA double-strand breaks: Prior to but not sufficient in targeting hypermutation
-
Bross L., Muramatsu M., Kinoshita K., Honjo T., and Jacobs H. DNA double-strand breaks: Prior to but not sufficient in targeting hypermutation. J. Exp. Med. 195 (2002) 1187-1192
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1187-1192
-
-
Bross, L.1
Muramatsu, M.2
Kinoshita, K.3
Honjo, T.4
Jacobs, H.5
-
16
-
-
0032522564
-
Ku80 is required for immunoglobulin isotype switching
-
Casellas R., Nussenzweig A., Wuerffel R., Pelanda R., Reichlin A., Suh H., Qin X.F., Besmer E., Kenter A., Rajewsky K., and Nussenzweig M.C. Ku80 is required for immunoglobulin isotype switching. EMBO J. 17 (1998) 2404-2411
-
(1998)
EMBO J.
, vol.17
, pp. 2404-2411
-
-
Casellas, R.1
Nussenzweig, A.2
Wuerffel, R.3
Pelanda, R.4
Reichlin, A.5
Suh, H.6
Qin, X.F.7
Besmer, E.8
Kenter, A.9
Rajewsky, K.10
Nussenzweig, M.C.11
-
17
-
-
0042931069
-
The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch μ region
-
Catalan N., Selz F., Imai K., Revy P., Fischer A., and Durandy A. The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch μ region. J. Immunol. 171 (2003) 2504-2509
-
(2003)
J. Immunol.
, vol.171
, pp. 2504-2509
-
-
Catalan, N.1
Selz, F.2
Imai, K.3
Revy, P.4
Fischer, A.5
Durandy, A.6
-
18
-
-
0037452080
-
Transcription-targeted DNA deamination by the AID antibody diversification enzyme
-
Chaudhuri J., Tian M., Khuong C., Chua K., Pinaud E., and Alt F.W. Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature 422 (2003) 726-730
-
(2003)
Nature
, vol.422
, pp. 726-730
-
-
Chaudhuri, J.1
Tian, M.2
Khuong, C.3
Chua, K.4
Pinaud, E.5
Alt, F.W.6
-
19
-
-
4344700569
-
Replication protein A interacts with AID to promote deamination of somatic hypermutation targets
-
Chaudhuri J., Khuong C., and Alt F.W. Replication protein A interacts with AID to promote deamination of somatic hypermutation targets. Nature 430 (2004) 992-998
-
(2004)
Nature
, vol.430
, pp. 992-998
-
-
Chaudhuri, J.1
Khuong, C.2
Alt, F.W.3
-
20
-
-
20644438238
-
Mutations at arginine 276 transform human uracil-DNA glycosylase into a single-stranded DNA-specific uracil-DNA glycosylase
-
Chen C.Y., Mosbaugh D.W., and Bennett S.E. Mutations at arginine 276 transform human uracil-DNA glycosylase into a single-stranded DNA-specific uracil-DNA glycosylase. DNA Repair (Amst.) 4 (2005) 793-805
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 793-805
-
-
Chen, C.Y.1
Mosbaugh, D.W.2
Bennett, S.E.3
-
21
-
-
3142651460
-
Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages
-
Chen R., Le Rouzic E., Kearney J.A., Mansky L.M., and Benichou S. Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages. J. Biol. Chem. 279 (2004) 28419-28425
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28419-28425
-
-
Chen, R.1
Le Rouzic, E.2
Kearney, J.A.3
Mansky, L.M.4
Benichou, S.5
-
22
-
-
0041524056
-
The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay
-
Chester A., Somasekaram A., Tzimina M., Jarmuz A., Gisbourne J., O'Keefe R., Scott J., and Navaratnam N. The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay. EMBO J. 22 (2003) 3971-3982
-
(2003)
EMBO J.
, vol.22
, pp. 3971-3982
-
-
Chester, A.1
Somasekaram, A.2
Tzimina, M.3
Jarmuz, A.4
Gisbourne, J.5
O'Keefe, R.6
Scott, J.7
Navaratnam, N.8
-
24
-
-
0037026482
-
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
-
Di Noia J., and Neuberger M.S. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature 419 (2002) 43-48
-
(2002)
Nature
, vol.419
, pp. 43-48
-
-
Di Noia, J.1
Neuberger, M.S.2
-
25
-
-
1642345456
-
Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID-mediated deoxycytidine deamination
-
Di Noia J.M., and Neuberger M.S. Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID-mediated deoxycytidine deamination. Eur. J. Immunol. 34 (2004) 504-508
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 504-508
-
-
Di Noia, J.M.1
Neuberger, M.S.2
-
26
-
-
32544439248
-
SMUG1 is able to excise uracil from immunoglobulin genes: Insight into mutation versus repair
-
Di Noia J.M., Rada C., and Neuberger M.S. SMUG1 is able to excise uracil from immunoglobulin genes: Insight into mutation versus repair. EMBO J. 25 (2006) 585-595
-
(2006)
EMBO J.
, vol.25
, pp. 585-595
-
-
Di Noia, J.M.1
Rada, C.2
Neuberger, M.S.3
-
28
-
-
0027398544
-
CD40 ligand mutations in x-linked immunodeficiency with hyper-IgM
-
DiSanto J.P., Bonnefoy J.Y., Gauchat J.F., Fischer A., and de Saint Basile G. CD40 ligand mutations in x-linked immunodeficiency with hyper-IgM. Nature 361 (1993) 541-543
-
(1993)
Nature
, vol.361
, pp. 541-543
-
-
DiSanto, J.P.1
Bonnefoy, J.Y.2
Gauchat, J.F.3
Fischer, A.4
de Saint Basile, G.5
-
29
-
-
0037418279
-
De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
-
Doi T., Kinoshita K., Ikegawa M., Muramatsu M., and Honjo T. De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination. Proc. Natl. Acad. Sci. USA 100 (2003) 2634-2638
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2634-2638
-
-
Doi, T.1
Kinoshita, K.2
Ikegawa, M.3
Muramatsu, M.4
Honjo, T.5
-
30
-
-
0037162518
-
Internal IgH class switch region deletions are position-independent and enhanced by AID expression
-
Dudley D.D., Manis J.P., Zarrin A.A., Kaylor L., Tian M., and Alt F.W. Internal IgH class switch region deletions are position-independent and enhanced by AID expression. Proc. Natl. Acad. Sci. USA 99 (2002) 9984-9989
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9984-9989
-
-
Dudley, D.D.1
Manis, J.P.2
Zarrin, A.A.3
Kaylor, L.4
Tian, M.5
Alt, F.W.6
-
31
-
-
0027303118
-
Induction by anti-CD40 antibody or soluble CD40 ligand and cytokines of IgG, IgA and IgE production by B cells from patients with X-linked hyper IgM syndrome
-
Durandy A., Schiff C., Bonnefoy J.Y., Forveille M., Rousset F., Mazzei G., Milili M., and Fischer A. Induction by anti-CD40 antibody or soluble CD40 ligand and cytokines of IgG, IgA and IgE production by B cells from patients with X-linked hyper IgM syndrome. Eur. J. Immunol. 23 (1993) 2294-2299
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 2294-2299
-
-
Durandy, A.1
Schiff, C.2
Bonnefoy, J.Y.3
Forveille, M.4
Rousset, F.5
Mazzei, G.6
Milili, M.7
Fischer, A.8
-
32
-
-
0242331621
-
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
-
Eto T., Kinoshita K., Yoshikawa K., Muramatsu M., and Honjo T. RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells. Proc. Natl. Acad. Sci. USA 100 (2003) 12895-12898
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12895-12898
-
-
Eto, T.1
Kinoshita, K.2
Yoshikawa, K.3
Muramatsu, M.4
Honjo, T.5
-
33
-
-
0029001413
-
Immunohistologic analysis of ineffective CD40-CD40 ligand interaction in lymphoid tissues from patients with X-linked immunodeficiency with hyper-IgM. Abortive germinal center cell reaction and severe depletion of follicular dendritic cells
-
Facchetti F., Appiani C., Salvi L., Levy J., and Notarangelo L.D. Immunohistologic analysis of ineffective CD40-CD40 ligand interaction in lymphoid tissues from patients with X-linked immunodeficiency with hyper-IgM. Abortive germinal center cell reaction and severe depletion of follicular dendritic cells. J. Immunol. 154 (1995) 6624-6633
-
(1995)
J. Immunol.
, vol.154
, pp. 6624-6633
-
-
Facchetti, F.1
Appiani, C.2
Salvi, L.3
Levy, J.4
Notarangelo, L.D.5
-
34
-
-
0037112050
-
Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora
-
Fagarasan S., Muramatsu M., Suzuki K., Nagaoka H., Hiai H., and Honjo T. Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science 298 (2002) 1424-1427
-
(2002)
Science
, vol.298
, pp. 1424-1427
-
-
Fagarasan, S.1
Muramatsu, M.2
Suzuki, K.3
Nagaoka, H.4
Hiai, H.5
Honjo, T.6
-
35
-
-
0036732772
-
AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line
-
Faili A., Aoufouchi S., Gueranger Q., Zober C., Leon A., Bertocci B., Weill J.C., and Reynaud C.A. AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line. Nat. Immunol. 3 (2002) 815-821
-
(2002)
Nat. Immunol.
, vol.3
, pp. 815-821
-
-
Faili, A.1
Aoufouchi, S.2
Gueranger, Q.3
Zober, C.4
Leon, A.5
Bertocci, B.6
Weill, J.C.7
Reynaud, C.A.8
-
36
-
-
0032489920
-
B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin α-dependent fashion
-
Fu Y.X., Huang G., Wang Y., and Chaplin D.D. B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin α-dependent fashion. J. Exp. Med. 187 (1998) 1009-1018
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1009-1018
-
-
Fu, Y.X.1
Huang, G.2
Wang, Y.3
Chaplin, D.D.4
-
37
-
-
1642370059
-
Non-redundancy of cytidine deaminases in class switch recombination
-
Fugmann S.D., Rush J.S., and Schatz D.G. Non-redundancy of cytidine deaminases in class switch recombination. Eur. J. Immunol. 34 (2004) 844-849
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 844-849
-
-
Fugmann, S.D.1
Rush, J.S.2
Schatz, D.G.3
-
38
-
-
0032127810
-
Somatic hypermutation in the heavy chain locus correlates with transcription
-
Fukita Y., Jacobs H., and Rajewsky K. Somatic hypermutation in the heavy chain locus correlates with transcription. Immunity 9 (1998) 105-114
-
(1998)
Immunity
, vol.9
, pp. 105-114
-
-
Fukita, Y.1
Jacobs, H.2
Rajewsky, K.3
-
39
-
-
0027379443
-
Role of CD40-CD40-ligand interaction in Ig-isotype switching
-
Fuleihan R., Ramesh N., and Geha R.S. Role of CD40-CD40-ligand interaction in Ig-isotype switching. Curr. Opin. Immunol. 5 (1993) 963-967
-
(1993)
Curr. Opin. Immunol.
, vol.5
, pp. 963-967
-
-
Fuleihan, R.1
Ramesh, N.2
Geha, R.S.3
-
40
-
-
0036136321
-
Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine
-
Hamada H., Hiroi T., Nishiyama Y., Takahashi H., Masunaga Y., Hachimura S., Kaminogawa S., Takahashi-Iwanaga H., Iwanaga T., Kiyono H., Yamamoto H., and Ishikawa H. Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine. J. Immunol. 168 (2002) 57-64
-
(2002)
J. Immunol.
, vol.168
, pp. 57-64
-
-
Hamada, H.1
Hiroi, T.2
Nishiyama, Y.3
Takahashi, H.4
Masunaga, Y.5
Hachimura, S.6
Kaminogawa, S.7
Takahashi-Iwanaga, H.8
Iwanaga, T.9
Kiyono, H.10
Yamamoto, H.11
Ishikawa, H.12
-
41
-
-
0036863733
-
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators
-
Harris R.S., Petersen-Mahrt S.K., and Neuberger M.S. RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators. Mol. Cell 10 (2002) 1247-1253
-
(2002)
Mol. Cell
, vol.10
, pp. 1247-1253
-
-
Harris, R.S.1
Petersen-Mahrt, S.K.2
Neuberger, M.S.3
-
42
-
-
0036212917
-
Molecular mechanism of class switch recombination: Linkage with somatic hypermutation
-
Honjo T., Kinoshita K., and Muramatsu M. Molecular mechanism of class switch recombination: Linkage with somatic hypermutation. Annu. Rev. Immunol. 20 (2002) 165-196
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 165-196
-
-
Honjo, T.1
Kinoshita, K.2
Muramatsu, M.3
-
44
-
-
85047693702
-
Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination
-
Imai K., Catalan N., Plebani A., Marodi L., Sanal O., Kumaki S., Nagendran V., Wood P., Glastre C., Sarrot-Reynauld F., Hermine O., Forveille M., et al. Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination. J. Clin. Invest. 112 (2003) 136-142
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 136-142
-
-
Imai, K.1
Catalan, N.2
Plebani, A.3
Marodi, L.4
Sanal, O.5
Kumaki, S.6
Nagendran, V.7
Wood, P.8
Glastre, C.9
Sarrot-Reynauld, F.10
Hermine, O.11
Forveille, M.12
-
45
-
-
1242341972
-
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
-
Ito S., Nagaoka H., Shinkura R., Begum N., Muramatsu M., Nakata M., and Honjo T. Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1. Proc. Natl. Acad. Sci. USA 101 (2004) 1975-1980
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1975-1980
-
-
Ito, S.1
Nagaoka, H.2
Shinkura, R.3
Begum, N.4
Muramatsu, M.5
Nakata, M.6
Honjo, T.7
-
46
-
-
0030035663
-
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase
-
Kavli B., Slupphaug G., Mol C.D., Arvai A.S., Peterson S.B., Tainer J.A., and Krokan H.E. Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase. EMBO J. 15 (1996) 3442-3447
-
(1996)
EMBO J.
, vol.15
, pp. 3442-3447
-
-
Kavli, B.1
Slupphaug, G.2
Mol, C.D.3
Arvai, A.S.4
Peterson, S.B.5
Tainer, J.A.6
Krokan, H.E.7
-
47
-
-
22344453737
-
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil
-
Kavli B., Andersen S., Otterlei M., Liabakk N.B., Imai K., Fischer A., Durandy A., Krokan H.E., and Slupphaug G. B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil. J. Exp. Med. 201 (2005) 2011-2021
-
(2005)
J. Exp. Med.
, vol.201
, pp. 2011-2021
-
-
Kavli, B.1
Andersen, S.2
Otterlei, M.3
Liabakk, N.B.4
Imai, K.5
Fischer, A.6
Durandy, A.7
Krokan, H.E.8
Slupphaug, G.9
-
48
-
-
0032428658
-
Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions
-
Kinoshita K., Tashiro J., Tomita S., Lee C.G., and Honjo T. Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions. Immunity 9 (1998) 849-858
-
(1998)
Immunity
, vol.9
, pp. 849-858
-
-
Kinoshita, K.1
Tashiro, J.2
Tomita, S.3
Lee, C.G.4
Honjo, T.5
-
49
-
-
27844555425
-
Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen
-
Ko R., and Bennett S.E. Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen. DNA Repair (Amst.) 4 (2005) 1421-1431
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 1421-1431
-
-
Ko, R.1
Bennett, S.E.2
-
50
-
-
0035003254
-
DNA breaks in hypermutating immunoglobulin genes: Evidence for a break-and-repair pathway of somatic hypermutation
-
Kong Q., and Maizels N. DNA breaks in hypermutating immunoglobulin genes: Evidence for a break-and-repair pathway of somatic hypermutation. Genetics 158 (2001) 369-378
-
(2001)
Genetics
, vol.158
, pp. 369-378
-
-
Kong, Q.1
Maizels, N.2
-
51
-
-
0027533185
-
Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM
-
Korthauer U., Graf D., Mages H.W., Briere F., Padayachee M., Malcolm S., Ugazio A.G., Notarangelo L.D., Levinsky R.J., and Kroczek R.A. Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM. Nature 361 (1993) 539-541
-
(1993)
Nature
, vol.361
, pp. 539-541
-
-
Korthauer, U.1
Graf, D.2
Mages, H.W.3
Briere, F.4
Padayachee, M.5
Malcolm, S.6
Ugazio, A.G.7
Notarangelo, L.D.8
Levinsky, R.J.9
Kroczek, R.A.10
-
52
-
-
15444366646
-
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
-
Kotani A., Okazaki I.M., Muramatsu M., Kinoshita K., Begum N.A., Nakajima T., Saito H., and Honjo T. A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression. Proc. Natl. Acad. Sci. USA 102 (2005) 4506-4511
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4506-4511
-
-
Kotani, A.1
Okazaki, I.M.2
Muramatsu, M.3
Kinoshita, K.4
Begum, N.A.5
Nakajima, T.6
Saito, H.7
Honjo, T.8
-
53
-
-
0029548868
-
Tumor necrosis factor receptor-1 signaling is required for differentiation of follicular dendritic cells, germinal center formation, and full antibody responses
-
Le Hir M., Bluethmann H., Kosco-Vilbois M.H., Muller M., di Padova F., Moore M., Ryffel B., and Eugster H.P. Tumor necrosis factor receptor-1 signaling is required for differentiation of follicular dendritic cells, germinal center formation, and full antibody responses. J. Inflamm. 47 (1995) 76-80
-
(1995)
J. Inflamm.
, vol.47
, pp. 76-80
-
-
Le Hir, M.1
Bluethmann, H.2
Kosco-Vilbois, M.H.3
Muller, M.4
di Padova, F.5
Moore, M.6
Ryffel, B.7
Eugster, H.P.8
-
54
-
-
30344472683
-
MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells
-
MacDuff D.A., Neuberger M.S., and Harris R.S. MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells. Mol. Immunol. 43 (2006) 1099-1108
-
(2006)
Mol. Immunol.
, vol.43
, pp. 1099-1108
-
-
MacDuff, D.A.1
Neuberger, M.S.2
Harris, R.S.3
-
55
-
-
0030806321
-
Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice
-
Mackay F., Majeau G.R., Lawton P., Hochman P.S., and Browning J.L. Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice. Eur. J. Immunol. 27 (1997) 2033-2042
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 2033-2042
-
-
Mackay, F.1
Majeau, G.R.2
Lawton, P.3
Hochman, P.S.4
Browning, J.L.5
-
56
-
-
0032526290
-
Ku70 is required for late B cell development and immunoglobulin heavy chain class switching
-
Manis J.P., Gu Y., Lansford R., Sonoda E., Ferrini R., Davidson L., Rajewsky K., and Alt F.W. Ku70 is required for late B cell development and immunoglobulin heavy chain class switching. J. Exp. Med. 187 (1998) 2081-2089
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2081-2089
-
-
Manis, J.P.1
Gu, Y.2
Lansford, R.3
Sonoda, E.4
Ferrini, R.5
Davidson, L.6
Rajewsky, K.7
Alt, F.W.8
-
57
-
-
0036224604
-
IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells
-
Manis J.P., Dudley D., Kaylor L., and Alt F.W. IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells. Immunity 16 (2002) 607-617
-
(2002)
Immunity
, vol.16
, pp. 607-617
-
-
Manis, J.P.1
Dudley, D.2
Kaylor, L.3
Alt, F.W.4
-
58
-
-
0033925801
-
The interaction of vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 in vivo mutation rate
-
Mansky L.M., Preveral S., Selig L., Benarous R., and Benichou S. The interaction of vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 in vivo mutation rate. J. Virol. 74 (2000) 7039-7047
-
(2000)
J. Virol.
, vol.74
, pp. 7039-7047
-
-
Mansky, L.M.1
Preveral, S.2
Selig, L.3
Benarous, R.4
Benichou, S.5
-
59
-
-
0037126038
-
Somatic hypermutation of the AID transgene in B and non-B cells
-
Martin A., and Scharff M.D. Somatic hypermutation of the AID transgene in B and non-B cells. Proc. Natl. Acad. Sci. USA 99 (2002) 12304-12308
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12304-12308
-
-
Martin, A.1
Scharff, M.D.2
-
60
-
-
0037074975
-
Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas
-
Martin A., Bardwell P.D., Woo C.J., Fan M., Shulman M.J., and Scharff M.D. Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas. Nature 415 (2002) 802-806
-
(2002)
Nature
, vol.415
, pp. 802-806
-
-
Martin, A.1
Bardwell, P.D.2
Woo, C.J.3
Fan, M.4
Shulman, M.J.5
Scharff, M.D.6
-
61
-
-
0006379753
-
Affinity maturation without germinal centres in lymphotoxin-α-deficient mice
-
Matsumoto M., Lo S.F., Carruthers C.J., Min J., Mariathasan S., Huang G., Plas D.R., Martin S.M., Geha R.S., Nahm M.H., and Chaplin D.D. Affinity maturation without germinal centres in lymphotoxin-α-deficient mice. Nature 382 (1996) 426-462
-
(1996)
Nature
, vol.382
, pp. 426-462
-
-
Matsumoto, M.1
Lo, S.F.2
Carruthers, C.J.3
Min, J.4
Mariathasan, S.5
Huang, G.6
Plas, D.R.7
Martin, S.M.8
Geha, R.S.9
Nahm, M.H.10
Chaplin, D.D.11
-
62
-
-
2442474264
-
Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase
-
McBride K.M., Barreto V., Ramiro A.R., Stavropoulos P., and Nussenzweig M.C. Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase. J. Exp. Med. 199 (2004) 1235-1244
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1235-1244
-
-
McBride, K.M.1
Barreto, V.2
Ramiro, A.R.3
Stavropoulos, P.4
Nussenzweig, M.C.5
-
63
-
-
0033970066
-
Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA
-
Mehta A., Kinter M.T., Sherman N.E., and Driscoll D.M. Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA. Mol. Cell. Biol. 20 (2000) 1846-1854
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1846-1854
-
-
Mehta, A.1
Kinter, M.T.2
Sherman, N.E.3
Driscoll, D.M.4
-
64
-
-
0034200558
-
1H, 15N and 13C resonance assignments for the C-terminal protein interaction region of the 32 kDa subunit of human replication protein A
-
Mer G., Edwards A.M., and Chazin W.J. 1H, 15N and 13C resonance assignments for the C-terminal protein interaction region of the 32 kDa subunit of human replication protein A. J. Biomol. NMR 17 (2000) 179-180
-
(2000)
J. Biomol. NMR
, vol.17
, pp. 179-180
-
-
Mer, G.1
Edwards, A.M.2
Chazin, W.J.3
-
65
-
-
0028934537
-
Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis
-
Mol C.D., Arvai A.S., Slupphaug G., Kavli B., Alseth I., Krokan H.E., and Tainer J.A. Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis. Cell 80 (1995) 869-878
-
(1995)
Cell
, vol.80
, pp. 869-878
-
-
Mol, C.D.1
Arvai, A.S.2
Slupphaug, G.3
Kavli, B.4
Alseth, I.5
Krokan, H.E.6
Tainer, J.A.7
-
66
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
-
Morgan H.D., Dean W., Coker H.A., Reik W., and Petersen-Mahrt S.K. Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming. J. Biol. Chem. 279 (2004) 52353-52360
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52353-52360
-
-
Morgan, H.D.1
Dean, W.2
Coker, H.A.3
Reik, W.4
Petersen-Mahrt, S.K.5
-
67
-
-
0033603340
-
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
-
Muramatsu M., Sankaranand V.S., Anant S., Sugai M., Kinoshita K., Davidson N.O., and Honjo T. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J. Biol. Chem. 274 (1999) 18470-18476
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18470-18476
-
-
Muramatsu, M.1
Sankaranand, V.S.2
Anant, S.3
Sugai, M.4
Kinoshita, K.5
Davidson, N.O.6
Honjo, T.7
-
68
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M., Kinoshita K., Fagarasan S., Yamada S., Shinkai Y., and Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102 (2000) 553-563
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
69
-
-
2942537762
-
The transcriptional programme of antibody class switching involves the repressor Bach2
-
Muto A., Tashiro S., Nakajima O., Hoshino H., Takahashi S., Sakoda E., Ikebe D., Yamamoto M., and Igarashi K. The transcriptional programme of antibody class switching involves the repressor Bach2. Nature 429 (2004) 566-571
-
(2004)
Nature
, vol.429
, pp. 566-571
-
-
Muto, A.1
Tashiro, S.2
Nakajima, O.3
Hoshino, H.4
Takahashi, S.5
Sakoda, E.6
Ikebe, D.7
Yamamoto, M.8
Igarashi, K.9
-
70
-
-
0034662773
-
Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene
-
Muto T., Muramatsu M., Taniwaki M., Kinoshita K., and Honjo T. Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene. Genomics 68 (2000) 85-88
-
(2000)
Genomics
, vol.68
, pp. 85-88
-
-
Muto, T.1
Muramatsu, M.2
Taniwaki, M.3
Kinoshita, K.4
Honjo, T.5
-
71
-
-
0037128169
-
Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Sμ region: Implication of AID involvement in a common step of class switch recombination and somatic hypermutation
-
Nagaoka H., Muramatsu M., Yamamura N., Kinoshita K., and Honjo T. Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Sμ region: Implication of AID involvement in a common step of class switch recombination and somatic hypermutation. J. Exp. Med. 195 (2002) 529-534
-
(2002)
J. Exp. Med.
, vol.195
, pp. 529-534
-
-
Nagaoka, H.1
Muramatsu, M.2
Yamamura, N.3
Kinoshita, K.4
Honjo, T.5
-
72
-
-
13844315325
-
DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase
-
Nagaoka H., Ito S., Muramatsu M., Nakata M., and Honjo T. DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase. Proc. Natl. Acad. Sci. USA 102 (2005) 2022-2027
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2022-2027
-
-
Nagaoka, H.1
Ito, S.2
Muramatsu, M.3
Nakata, M.4
Honjo, T.5
-
73
-
-
0030996226
-
A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A
-
Nagelhus T.A., Haug T., Singh K.K., Keshav K.F., Skorpen F., Otterlei M., Bharati S., Lindmo T., Benichou S., Benarous R., and Krokan H.E. A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A. J. Biol. Chem. 272 (1997) 6561-6566
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6561-6566
-
-
Nagelhus, T.A.1
Haug, T.2
Singh, K.K.3
Keshav, K.F.4
Skorpen, F.5
Otterlei, M.6
Bharati, S.7
Lindmo, T.8
Benichou, S.9
Benarous, R.10
Krokan, H.E.11
-
75
-
-
0346362489
-
Transcription-coupled events associating with immunoglobulin switch region chromatin
-
Nambu Y., Sugai M., Gonda H., Lee C.G., Katakai T., Agata Y., Yokota Y., and Shimizu A. Transcription-coupled events associating with immunoglobulin switch region chromatin. Science 302 (2003) 2137-2140
-
(2003)
Science
, vol.302
, pp. 2137-2140
-
-
Nambu, Y.1
Sugai, M.2
Gonda, H.3
Lee, C.G.4
Katakai, T.5
Agata, Y.6
Yokota, Y.7
Shimizu, A.8
-
76
-
-
13144259628
-
Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition
-
Navaratnam N., Fujino T., Bayliss J., Jarmuz A., How A., Richardson N., Somasekaram A., Bhattacharya S., Carter C., and Scott J. Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition. J. Mol. Biol. 275 (1998) 695-714
-
(1998)
J. Mol. Biol.
, vol.275
, pp. 695-714
-
-
Navaratnam, N.1
Fujino, T.2
Bayliss, J.3
Jarmuz, A.4
How, A.5
Richardson, N.6
Somasekaram, A.7
Bhattacharya, S.8
Carter, C.9
Scott, J.10
-
79
-
-
22544443073
-
Histone modifications associated with somatic hypermutation
-
Odegard V.H., Kim S.T., Anderson S.M., Shlomchik M.J., and Schatz D.G. Histone modifications associated with somatic hypermutation. Immunity 23 (2005) 101-110
-
(2005)
Immunity
, vol.23
, pp. 101-110
-
-
Odegard, V.H.1
Kim, S.T.2
Anderson, S.M.3
Shlomchik, M.J.4
Schatz, D.G.5
-
80
-
-
0037149473
-
The AID enzyme induces class switch recombination in fibroblasts
-
Okazaki I.M., Kinoshita K., Muramatsu M., Yoshikawa K., and Honjo T. The AID enzyme induces class switch recombination in fibroblasts. Nature 416 (2002) 340-345
-
(2002)
Nature
, vol.416
, pp. 340-345
-
-
Okazaki, I.M.1
Kinoshita, K.2
Muramatsu, M.3
Yoshikawa, K.4
Honjo, T.5
-
81
-
-
0037881911
-
Constitutive expression of AID leads to tumorigenesis
-
Okazaki I.M., Hiai H., Kakazu N., Yamada S., Muramatsu M., Kinoshita K., and Honjo T. Constitutive expression of AID leads to tumorigenesis. J. Exp. Med. 197 (2003) 1173-1181
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1173-1181
-
-
Okazaki, I.M.1
Hiai, H.2
Kakazu, N.3
Yamada, S.4
Muramatsu, M.5
Kinoshita, K.6
Honjo, T.7
-
82
-
-
0032531934
-
Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively
-
Otterlei M., Haug T., Nagelhus T.A., Slupphaug G., Lindmo T., and Krokan H.E. Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively. Nucleic Acids Res. 26 (1998) 4611-4617
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 4611-4617
-
-
Otterlei, M.1
Haug, T.2
Nagelhus, T.A.3
Slupphaug, G.4
Lindmo, T.5
Krokan, H.E.6
-
83
-
-
0033168183
-
Post-replicative base excision repair in replication foci
-
Otterlei M., Warbrick E., Nagelhus T.A., Haug T., Slupphaug G., Akbari M., Aas P.A., Steinsbekk K., Bakke O., and Krokan H.E. Post-replicative base excision repair in replication foci. EMBO J. 18 (1999) 3834-3844
-
(1999)
EMBO J.
, vol.18
, pp. 3834-3844
-
-
Otterlei, M.1
Warbrick, E.2
Nagelhus, T.A.3
Haug, T.4
Slupphaug, G.5
Akbari, M.6
Aas, P.A.7
Steinsbekk, K.8
Bakke, O.9
Krokan, H.E.10
-
84
-
-
13244268505
-
Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells
-
Pan-Hammarstrom Q., Jones A.M., Lahdesmaki A., Zhou W., Gatti R.A., Hammarstrom L., Gennery A.R., and Ehrenstein M.R. Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells. J. Exp. Med. 201 (2005) 189-194
-
(2005)
J. Exp. Med.
, vol.201
, pp. 189-194
-
-
Pan-Hammarstrom, Q.1
Jones, A.M.2
Lahdesmaki, A.3
Zhou, W.4
Gatti, R.A.5
Hammarstrom, L.6
Gennery, A.R.7
Ehrenstein, M.R.8
-
85
-
-
0037029606
-
The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process
-
Papavasiliou F.N., and Schatz D.G. The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process. J. Exp. Med. 195 (2002) 1193-1198
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1193-1198
-
-
Papavasiliou, F.N.1
Schatz, D.G.2
-
86
-
-
0032167424
-
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA
-
Parikh S.S., Mol C.D., Slupphaug G., Bharati S., Krokan H.E., and Tainer J.A. Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. EMBO J. 17 (1998) 5214-5226
-
(1998)
EMBO J.
, vol.17
, pp. 5214-5226
-
-
Parikh, S.S.1
Mol, C.D.2
Slupphaug, G.3
Bharati, S.4
Krokan, H.E.5
Tainer, J.A.6
-
87
-
-
0034734383
-
Structure and function in the uracil-DNA glycosylase superfamily
-
Pearl L.H. Structure and function in the uracil-DNA glycosylase superfamily. Mutat. Res. 460 (2000) 165-181
-
(2000)
Mutat. Res.
, vol.460
, pp. 165-181
-
-
Pearl, L.H.1
-
88
-
-
0030063726
-
Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
-
Peters A., and Storb U. Somatic hypermutation of immunoglobulin genes is linked to transcription initiation. Immunity 4 (1996) 57-65
-
(1996)
Immunity
, vol.4
, pp. 57-65
-
-
Peters, A.1
Storb, U.2
-
89
-
-
0035818990
-
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
-
Petersen S., Casellas R., Reina-San-Martin B., Chen H.T., Difilippantonio M.J., Wilson P.C., Hanitsch L., Celeste A., Muramatsu M., Pilch D.R., Redon C., Ried T., et al. AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching. Nature 414 (2001) 660-665
-
(2001)
Nature
, vol.414
, pp. 660-665
-
-
Petersen, S.1
Casellas, R.2
Reina-San-Martin, B.3
Chen, H.T.4
Difilippantonio, M.J.5
Wilson, P.C.6
Hanitsch, L.7
Celeste, A.8
Muramatsu, M.9
Pilch, D.R.10
Redon, C.11
Ried, T.12
-
90
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt S.K., Harris R.S., and Neuberger M.S. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 418 (2002) 99-103
-
(2002)
Nature
, vol.418
, pp. 99-103
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
91
-
-
0037926476
-
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation
-
Pham P., Bransteitter R., Petruska J., and Goodman M.F. Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation. Nature 424 (2003) 103-107
-
(2003)
Nature
, vol.424
, pp. 103-107
-
-
Pham, P.1
Bransteitter, R.2
Petruska, J.3
Goodman, M.F.4
-
92
-
-
13944277344
-
HIV-1-associated uracil DNA glycosylase activity controls dUTP misincorporation in viral DNA and is essential to the HIV-1 life cycle
-
Priet S., Gros N., Navarro J.M., Boretto J., Canard B., Querat G., and Sire J. HIV-1-associated uracil DNA glycosylase activity controls dUTP misincorporation in viral DNA and is essential to the HIV-1 life cycle. Mol. Cell 17 (2005) 479-490
-
(2005)
Mol. Cell
, vol.17
, pp. 479-490
-
-
Priet, S.1
Gros, N.2
Navarro, J.M.3
Boretto, J.4
Canard, B.5
Querat, G.6
Sire, J.7
-
93
-
-
0037108463
-
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
-
Rada C., Williams G.T., Nilsen H., Barnes D.E., Lindahl T., and Neuberger M.S. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 12 (2002) 1748-1755
-
(2002)
Curr. Biol.
, vol.12
, pp. 1748-1755
-
-
Rada, C.1
Williams, G.T.2
Nilsen, H.3
Barnes, D.E.4
Lindahl, T.5
Neuberger, M.S.6
-
94
-
-
6344256944
-
Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation
-
Rada C., Di Noia J.M., and Neuberger M.S. Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation. Mol. Cell 16 (2004) 163-171
-
(2004)
Mol. Cell
, vol.16
, pp. 163-171
-
-
Rada, C.1
Di Noia, J.M.2
Neuberger, M.S.3
-
95
-
-
4644257592
-
AID is required for c-myc/IgH chromosome translocations in vivo
-
Ramiro A.R., Jankovic M., Eisenreich T., Difilippantonio S., Chen-Kiang S., Muramatsu M., Honjo T., Nussenzweig A., and Nussenzweig M.C. AID is required for c-myc/IgH chromosome translocations in vivo. Cell 118 (2004) 431-438
-
(2004)
Cell
, vol.118
, pp. 431-438
-
-
Ramiro, A.R.1
Jankovic, M.2
Eisenreich, T.3
Difilippantonio, S.4
Chen-Kiang, S.5
Muramatsu, M.6
Honjo, T.7
Nussenzweig, A.8
Nussenzweig, M.C.9
-
96
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
-
Revy P., Muto T., Levy Y., Geissmann F., Plebani A., Sanal O., Catalan N., Forveille M., Dufourcq-Labelouse R., Gennery A., Tezcan I., Ersoy F., et al. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell 102 (2000) 565-575
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
Muto, T.2
Levy, Y.3
Geissmann, F.4
Plebani, A.5
Sanal, O.6
Catalan, N.7
Forveille, M.8
Dufourcq-Labelouse, R.9
Gennery, A.10
Tezcan, I.11
Ersoy, F.12
-
97
-
-
0021255686
-
Demonstration of M cells in the specialized follicle-associated epithelium overlying isolated lymphoid follicles in the gut
-
Rosner A.J., and Keren D.F. Demonstration of M cells in the specialized follicle-associated epithelium overlying isolated lymphoid follicles in the gut. J. Leukoc. Biol. 35 (1984) 397-404
-
(1984)
J. Leukoc. Biol.
, vol.35
, pp. 397-404
-
-
Rosner, A.J.1
Keren, D.F.2
-
98
-
-
1842865725
-
Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to Sμ in Ig class switch recombination
-
Rush J.S., Fugmann S.D., and Schatz D.G. Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to Sμ in Ig class switch recombination. Int. Immunol. 16 (2004) 549-557
-
(2004)
Int. Immunol.
, vol.16
, pp. 549-557
-
-
Rush, J.S.1
Fugmann, S.D.2
Schatz, D.G.3
-
99
-
-
0031091733
-
Lack of type 2 T cell-independent B cell responses and defect in isotype switching in TNF-lymphotoxin α-deficient mice
-
Ryffel B., Di Padova F., Schreier M.H., Le Hir M., Eugster H.P., and Quesniaux V.F. Lack of type 2 T cell-independent B cell responses and defect in isotype switching in TNF-lymphotoxin α-deficient mice. J. Immunol. 158 (1997) 2126-2133
-
(1997)
J. Immunol.
, vol.158
, pp. 2126-2133
-
-
Ryffel, B.1
Di Padova, F.2
Schreier, M.H.3
Le Hir, M.4
Eugster, H.P.5
Quesniaux, V.F.6
-
100
-
-
0029115366
-
Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil glycosylase inhibitor protein complex
-
Savva R., and Pearl L.H. Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil glycosylase inhibitor protein complex. Nat. Struct. Biol. 2 (1995) 752-757
-
(1995)
Nat. Struct. Biol.
, vol.2
, pp. 752-757
-
-
Savva, R.1
Pearl, L.H.2
-
101
-
-
23944431983
-
Inducible DNA breaks in Ig S regions are dependent on AID and UNG
-
Schrader C.E., Linehan E.K., Mochegova S.N., Woodland R.T., and Stavnezer J. Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J. Exp. Med. 202 (2005) 561-568
-
(2005)
J. Exp. Med.
, vol.202
, pp. 561-568
-
-
Schrader, C.E.1
Linehan, E.K.2
Mochegova, S.N.3
Woodland, R.T.4
Stavnezer, J.5
-
102
-
-
0030958826
-
Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest
-
Selig L., Benichou S., Rogel M.E., Wu L.I., Vodicka M.A., Sire J., Benarous R., and Emerman M. Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest. J. Virol. 71 (1997) 4842-4846
-
(1997)
J. Virol.
, vol.71
, pp. 4842-4846
-
-
Selig, L.1
Benichou, S.2
Rogel, M.E.3
Wu, L.I.4
Vodicka, M.A.5
Sire, J.6
Benarous, R.7
Emerman, M.8
-
103
-
-
3242795967
-
Separate domains of AID are required for somatic hypermutation and class-switch recombination
-
Shinkura R., Ito S., Begum N.A., Nagaoka H., Muramatsu M., Kinoshita K., Sakakibara Y., Hijikata H., and Honjo T. Separate domains of AID are required for somatic hypermutation and class-switch recombination. Nat. Immunol. 5 (2004) 707-712
-
(2004)
Nat. Immunol.
, vol.5
, pp. 707-712
-
-
Shinkura, R.1
Ito, S.2
Begum, N.A.3
Nagaoka, H.4
Muramatsu, M.5
Kinoshita, K.6
Sakakibara, Y.7
Hijikata, H.8
Honjo, T.9
-
104
-
-
0029904839
-
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA
-
Slupphaug G., Mol C.D., Kavli B., Arvai A.S., Krokan H.E., and Tainer J.A. A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature 384 (1996) 82-92
-
(1996)
Nature
, vol.384
, pp. 82-92
-
-
Slupphaug, G.1
Mol, C.D.2
Kavli, B.3
Arvai, A.S.4
Krokan, H.E.5
Tainer, J.A.6
-
105
-
-
0029931447
-
Immunoglobulin class switching
-
Stavnezer J. Immunoglobulin class switching. Curr. Opin. Immunol. 8 (1996) 199-205
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 199-205
-
-
Stavnezer, J.1
-
106
-
-
22144494153
-
Depletion of uracil-DNA glycosylase activity is associated with decreased cell proliferation
-
Studebaker A.W., Ariza M.E., and Williams M.V. Depletion of uracil-DNA glycosylase activity is associated with decreased cell proliferation. Biochem. Biophys. Res. Commun. 334 (2005) 509-515
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.334
, pp. 509-515
-
-
Studebaker, A.W.1
Ariza, M.E.2
Williams, M.V.3
-
107
-
-
0041381361
-
AID mutant analyses indicate requirement for class-switch-specific cofactors
-
Ta V.T., Nagaoka H., Catalan N., Durandy A., Fischer A., Imai K., Nonoyama S., Tashiro J., Ikegawa M., Ito S., Kinoshita K., Muramatsu M., et al. AID mutant analyses indicate requirement for class-switch-specific cofactors. Nat. Immunol. 4 (2003) 843-848
-
(2003)
Nat. Immunol.
, vol.4
, pp. 843-848
-
-
Ta, V.T.1
Nagaoka, H.2
Catalan, N.3
Durandy, A.4
Fischer, A.5
Imai, K.6
Nonoyama, S.7
Tashiro, J.8
Ikegawa, M.9
Ito, S.10
Kinoshita, K.11
Muramatsu, M.12
-
108
-
-
0027200620
-
Molecular cloning of an apolipoprotein B messenger RNA editing protein
-
Teng B., Burant C.F., and Davidson N.O. Molecular cloning of an apolipoprotein B messenger RNA editing protein. Science 260 (1993) 1816-1819
-
(1993)
Science
, vol.260
, pp. 1816-1819
-
-
Teng, B.1
Burant, C.F.2
Davidson, N.O.3
-
109
-
-
0032958220
-
Mutational analysis of apolipoprotein B mRNA editing enzyme (APOBEC1). structure-function relationships of RNA editing and dimerization
-
Teng B.B., Ochsner S., Zhang Q., Soman K.V., Lau P.P., and Chan L. Mutational analysis of apolipoprotein B mRNA editing enzyme (APOBEC1). structure-function relationships of RNA editing and dimerization. J. Lipid Res. 40 (1999) 623-635
-
(1999)
J. Lipid Res.
, vol.40
, pp. 623-635
-
-
Teng, B.B.1
Ochsner, S.2
Zhang, Q.3
Soman, K.V.4
Lau, P.P.5
Chan, L.6
-
110
-
-
0020534965
-
Somatic generation of antibody diversity
-
Tonegawa S. Somatic generation of antibody diversity. Nature 302 (1983) 575-581
-
(1983)
Nature
, vol.302
, pp. 575-581
-
-
Tonegawa, S.1
-
111
-
-
33745853463
-
Identification of a specific domain required for dimerization of activation-induced cytidine deaminase
-
Wang J., Shinkura R., Muramatsu M., Nagaoka H., Kinoshita K., and Honjo T. Identification of a specific domain required for dimerization of activation-induced cytidine deaminase. J. Biol. Chem. 281 (2006) 19115-19123
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 19115-19123
-
-
Wang, J.1
Shinkura, R.2
Muramatsu, M.3
Nagaoka, H.4
Kinoshita, K.5
Honjo, T.6
-
112
-
-
0024587232
-
Uracil-DNA glycosylase inhibitor gene of bacteriophage PBS2 encodes a binding protein specific for uracil-DNA glycosylase
-
Wang Z., and Mosbaugh D.W. Uracil-DNA glycosylase inhibitor gene of bacteriophage PBS2 encodes a binding protein specific for uracil-DNA glycosylase. J. Biol. Chem. 264 (1989) 1163-1171
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 1163-1171
-
-
Wang, Z.1
Mosbaugh, D.W.2
-
113
-
-
0142188274
-
Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin
-
Woo C.J., Martin A., and Scharff M.D. Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin. Immunity 19 (2003) 479-489
-
(2003)
Immunity
, vol.19
, pp. 479-489
-
-
Woo, C.J.1
Martin, A.2
Scharff, M.D.3
-
114
-
-
11844264903
-
The double-edged sword of activation-induced cytidine deaminase
-
Wu X., Geraldes P., Platt J.L., and Cascalho M. The double-edged sword of activation-induced cytidine deaminase. J. Immunol. 174 (2005) 934-941
-
(2005)
J. Immunol.
, vol.174
, pp. 934-941
-
-
Wu, X.1
Geraldes, P.2
Platt, J.L.3
Cascalho, M.4
-
115
-
-
0033120232
-
Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: Structure and glycosylase mechanism revisited
-
Xiao G., Tordova M., Jagadeesh J., Drohat A.C., Stivers J.T., and Gilliland G.L. Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: Structure and glycosylase mechanism revisited. Proteins 35 (1999) 13-24
-
(1999)
Proteins
, vol.35
, pp. 13-24
-
-
Xiao, G.1
Tordova, M.2
Jagadeesh, J.3
Drohat, A.C.4
Stivers, J.T.5
Gilliland, G.L.6
-
116
-
-
0037076967
-
AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts
-
Yoshikawa K., Okazaki I.M., Eto T., Kinoshita K., Muramatsu M., Nagaoka H., and Honjo T. AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts. Science 296 (2002) 2033-2036
-
(2002)
Science
, vol.296
, pp. 2033-2036
-
-
Yoshikawa, K.1
Okazaki, I.M.2
Eto, T.3
Kinoshita, K.4
Muramatsu, M.5
Nagaoka, H.6
Honjo, T.7
-
117
-
-
1342282983
-
DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine
-
Yu K., Huang F.T., and Lieber M.R. DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine. J. Biol. Chem. 279 (2004) 6496-6500
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 6496-6500
-
-
Yu, K.1
Huang, F.T.2
Lieber, M.R.3
-
118
-
-
0037872240
-
Type two hyper-IgM syndrome caused by mutation in activation-induced cytidine deaminase
-
Zhu Y., Nonoyama S., Morio T., Muramatsu M., Honjo T., and Mizutani S. Type two hyper-IgM syndrome caused by mutation in activation-induced cytidine deaminase. J. Med. Dent. Sci. 50 (2003) 41-46
-
(2003)
J. Med. Dent. Sci.
, vol.50
, pp. 41-46
-
-
Zhu, Y.1
Nonoyama, S.2
Morio, T.3
Muramatsu, M.4
Honjo, T.5
Mizutani, S.6
|