Molecular cloning of apobec-1 complementation factor, a novel RNA- binding protein involved in the editing of apolipoprotein B mRNA

Molecular and Cellular Biology

Volumn 20, Issue 5, 2000, Pages 1846-1854

  Mehta, Anuradha ^a   Kinter, Michael T ^a,b   Sherman, Nicholas E ^b   Driscoll, Donna M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOBEC 1 COMPLEMENTATION FACTOR; APOLIPOPROTEIN B; COMPLEMENTARY DNA; MESSENGER RNA; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME PURIFICATION; ENZYME SUBUNIT; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN RNA BINDING; RNA EDITING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; APOLIPOPROTEINS B; CLONING, MOLECULAR; CYTIDINE DEAMINASE; DNA, COMPLEMENTARY; HUMANS; MOLECULAR SEQUENCE DATA; RATS; RNA EDITING; RNA, MESSENGER; RNA-BINDING PROTEINS;

EID: 0033970066     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.5.1846-1854.2000     Document Type: Article

References (45)

1. Anant, S., F. Giannoni, D. Antic, C. T. DeMaria, J. D. Keene, G. Brewer, and N. O. Davidson. 1997. AU-rich RNA binding proteins Hel-N1 and AUF1 bind apolipoprotein B mRNA and inhibit posttranscriptional C to U editing. Nucleic Acids Symp. Ser. 36:115-118.
2. Anant, S., A. J. MacGinnitie, and N. O. Davidson. 1995. apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, is a novel RNA-binding protein. J. Biol. Them. 270:14762-14767.
3. Bass, B. L. 1997. RNA editing and hypermutation by adenosine deamination. Trends Biochem. Sci. 22:157-162. (Erratum, 22:278.)
4. Burd, C. G., and G. Dreyfuss. 1994. Conserved structures and diversity of functions of RNA-binding proteins. Science 265:615-621.
5. Burd, C. G., and G. Dreyfuss. 1994. RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing. EMBO J. 13:1197-1204.
6. ft. Burd, C. G., E. L. Matunis, and G. Dreyfuss. 1991. The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities. Mol. Cell. Biol. 11:3419-3424.
7. Chan, L. 1992. Apolipoprotein B, the major protein component of triglyceride-rich and low density lipoproteins. J. Biol. Chem. 267:25621-25624.
8. Chan, L., B. H. Chang, M. Nakamuta, W. H. Li, and L. C. Smith. 1997. Apobec-1 and apolipoprotein B mRNA editing. Biochim. Biophys. Acta 1345:11-26.
9. Chen, S. H., G. Habib, C. Y. Yang, Z. W. Gu, B. R. Lee, S. A. Weng, S. R. Silberman, S. J. Cai, J. P. Deslypere, M. Rosseneu, et al. 1987 Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon. Science 238:363-366.
10. Driscoll, D. M., and E. Casanova. 1990. Characterization of the apolipoprotein B mRNA editing activity in enterocyte extracts. J. Biol. Chem. 265: 21401-21403.
11. Driscoll, D. M., S. Lakhe-Reddy, L. M. Oleksa, and D. Martinez. 1993. Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA. Mol. Cell. Biol. 13:7288-7294.
12. Driscoll, D. M., J. K. Wynne, S. C. Wallis, and J. Scott. 1989. An in vitro system for the editing of apolipoprotein B mRNA. Cell 58:519-525.
13. Driscoll, D. M., and Q. Zhang. 1994. Expression and characterization of p27, the catalytic subunit of the apolipoprotein B mRNA editing enzyme. J. Biol. Chem. 269:19843-19847.
14. Garcia, Z. C., K. S. Poksay, K. Bostrom, D. F. Johnson, M. E. Balestra, I. Shechter, and T. L. Innerarity. 1992. Characterization of apolipoprotein B mRNA editing from rabbit intestine. Arterioscler. Thromb. 12:172-179.
15. Giannoni, F., D. K. Bonen, T. Funahashi, C. Hadjiagapiou, C. F. Burant, and N. O. Davidson. 1994. Complementation of apolipoprotein B mRNA editing by human liver accompanied by secretion of apolipoprotein B48. J. Biol. Chem. 269:5932-5936.
16. Greeve, J., I. Altkemper, J. H. Dieterich, H. Greten, and E. Windler. 1993. Apolipoprotein B mRNA editing in 12 different mammalian species: hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins. J Lipid Res. 34:1367-1383.
17. Greeve, J., H. Lellek, P. Rautenberg, and H. Greten. 1998. Inhibition of the apolipoprotein B mRNA editing enzyme-complex by hnRNP C1 protein and 40S hnRNP complexes. Biol. Chem. 379:1063-1073.
18. Greeve, J., N. Navaratnam, and J. Scott. 1991. Characterization of the apolipoprotein B mRNA editing enzyme: no similarity to the proposed mechanism of RNA editing in kinetoplastid protozoa. Nucleic Acids Res. 19:3569-3576.
19. Hadjiagapiou, C., F. Giannoni, T. Funahashi, S. F. Skarosi, and N. O. Davidson. 1994. Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein. Nucleic Acids Res. 22:1874-1879.
20. Harris, S. G., I. Sabio, E. Mayer, M. F. Steinberg, J. W. Backus, J. D. Sparks, C. E, Sparks, and H. C. Smith. 1993. Extract-specific heterogeneity in high-order complexes containing apolipoprotein B mRNA editing activity and RNA-binding proteins. J. Biol, Chem. 268:7382-7392.
21. Innerarity, T. L., J. Boren, S. Yamanaka, and S. O. Olofsson. 1996. Biosynthesis of apolipoprotein B48-containing lipoproteins. Regulation by novel post-transcriptional mechanisms. J. Biol. Chem. 271:2353-2356.
22. Lau, P. P., S. H. Chen, J. C. Wang, and L. Chan. 1990. A 40 kilodalton rat liver nuclear protein binds specifically to apolipoprotein B mRNA around the RNA editing site. Nucleic Acids Res. 18:5817-5821.
23. Lau, P. P., W. J. Xiong, H. J. Zhu, S. H. Chen, and L. Chan. 1991. Apolipoprotein B mRNA editing is an intranuclear event that occurs posttranscriptionally coincident with splicing and polyadenylation. J. Biol. Chem. 266:20550-20554.
24. Lau, P. P., H. J. Zhu, A. Baldini, C. Charnsangavej, and L. Chan. 1994. Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene. Proc. Natl. Acad. Sci. USA 91:8522-8526.
25. Lau, P. P., H. J. Zhu, M. Nakamuta, and L. Chan. 1997. Cloning of an Aponec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing. J. Biol. Chem. 272:1452-1455.
26. Lutz, C. S., and J. C. Alwine. 1994. Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal. Genes Dev. 8:575-586.
27. Mehta, A., S. Banerjee, and D. M. Driscoll. 1996. Apobec-1 interacts with a 65-kDa complementing protein to edit apolipoprotein-B mRNA in vitro. J. Biol. Chem. 271:28294-28299.
28. Mehta, A., and D. M. Driscoll. 1998. A sequence-specific RNA-binding protein complements apobec-1 to edit apolipoprotein B mRNA. Mol. Cell. Biol. 18:4426-4432.
29. Navaratnam, N., S. Bhattacharya, T. Fujino, D. Patel, A. L. Jarmuz, and J. Scott. 1995. Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site. Cell 81:187-195.
30. Navaratnam, N., T. Fujino, J. Bayliss, A. Jarmuz, A. How, N. Richardson, A. Somasekaram, S. Bhattacharya, C. Carter, and J. Scott. 1998. Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition. J. Mol. Biol. 275:695-714.
31. Navaratnam, N., J. R. Morrison, S. Bhattacharya, D. Patel, T. Funahashi, F. Giannoni, B. B. Teng, N. O. Davidson, and J. Scott. 1993. The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase. J. Biol. Chem. 268:20709-20712.
32. Navaratnam, N., R. Shah, D. Patel, V. Fay, and J. Scott. 1993 Apolipoprotein B mRNA editing is associated with UV crosslinking of proteins to the editing site. Proc. Natl. Acad. Sci. USA 90:222-226.
33. O'Connell, M. A., S. Krause, M. Higuchi, J. J. Hsuan, N. F. Totty, A. Jenny, and W. Keller. 1995. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. Mol. Cell. Biol. 15:1389-1397.
34. Powell, L. M., S. C. Wallis, R. J. Pease, Y. H. Edwards, T. J. Knott, and J. Scott. 1987. A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine. Cell 50:831-840.
35. Schock, D., S. R. Kuo, M. F. Steinburg, M. Bolognino, J. D. Sparks, C. E. Sparks, and H. C, Smith. 1996. An auxiliary factor containing a 240-kDa protein complex is involved in apolipoprotein B RNA editing. Proc. Natl. Acad. Sci. USA 93:1097-1102.
36. Shah, R. R., T. J. Knott, J. E. Legros, N. Navaratnam, J. C. Greeve, and J. Scott. 1991. Sequence requirements for the editing of apolipoprotein B mRNA. J. Biol. Chem. 266:16301-16304.
37. Shevchenko, A., M. Wilm, O. Vorm, and M. Mann. 1996. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68: 850-858.
38. Simpson, L., and R. B. Emeson. 1996. RNA editing. Annu. Rev. Neurosci. 19:27-52.
39. Smith, H. C., J. M. Gott, and M. R. Hanson. 1997. A guide to RNA editing. RNA 3:1105-1123.
40. Smith, H. C., S. R. Kuo, J. W. Backus, S. G. Harris, C. E. Sparks, and J. D. Sparks. 1991. In vitro apolipoprotein B mRNA editing: identification of a 27S editing complex. Proe. Natl. Acad. Sci. USA 88:1489-1493.
41. Smith, H. C., and M. P. Sowden. 1996. Base-modification mRNA editing through deamination - the good, the bad and the unregulated. Trends Genet. 12:418-424.
42. Teng, B., C. F. Burant. and N. O. Davidson. 1993. Molecular cloning of an apolipoprotein B messenger RNA editing protein. Science 260:1816-1819.
43. Teng, B., and N. O. Davidson. 1992. Evolution of intestinal apolipoprotein B mRNA editing. Chicken apolipoprotein B mRNA is not edited, but chicken enterocytes contain in vitro editing enhancement factor(s). J. Biol. Chem. 267:21265-21272.
44. Yamanaka, S., K. S. Poksay, M. E. Balestra, G. Q. Zeng, and T. L. Innerarily. 1994. Cloning and mutagenesis of the rabbit ApoB mRNA editing protein. A zinc motif is essential for catalytic activity, and noncatalytic auxiliary factor(s) of the editing complex are widely distributed. J. Biol. Chem. 269:21725-21734.
45. Yang, Y., K. Kovalski, and H. C. Smith. 1997. Partial characterization of the auxiliary factors involved in apolipoprotein B mRNA editing through APOBEC-1 affinity chromatography. J. Biol. Chem. 272:27700-277116.