Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages

Journal of Biological Chemistry

Volumn 279, Issue 27, 2004, Pages 28419-28425

  Chen, Renxiang ^b   Le Rouzic, Erwann ^c   Kearney, Jessica A ^a   Mansky, Louis M ^a,b   Benichou, Serge ^c  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c INSTITUT COCHIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENZYMES; IMMUNOLOGY; MUTAGENESIS; VIRUSES;

MACROPHAGES; VIRIONS;

CELLS;

POLYDEOXYRIBONUCLEOTIDE SYNTHASE; URACIL DNA GLYCOSYLTRANSFERASE; VPR PROTEIN;

ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS 1; LIFE CYCLE; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; VIRION; VIRUS MUTATION; VIRUS PARTICLE; VIRUS REPLICATION;

BLOTTING, WESTERN; CATALYSIS; CELL LINE; DNA GLYCOSYLASES; DNA REPAIR; DNA REPLICATION; GENES, VPR; GLUTATHIONE TRANSFERASE; HELA CELLS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MONOCYTES; MUTATION; PLASMIDS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; RETROVIRIDAE; TIME FACTORS; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES; URACIL-DNA GLYCOSIDASE; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 3142651460     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403875200     Document Type: Article

References (49)

1. Cohen, E. A., Dehni, G., Sodroski, J. G., and Haseltine, W. A. (1990) J. Virol. 64, 3097-3099
2. Lu, Y. L., Spearman, P., and Ratner, L. (1993) J. Virol. 67, 6542-6550
3. Paxton, W., Connor, R. I., and Landau, N. R. (1993) J. Virol. 67, 7229-7237
4. Le Rouzic, E., Mousnier, A., Rustum, C., Stutz, F., Hallberg, E., Dargemont, C., and Benichou, S. (2002) J. Biol. Chem. 277, 45091-45098
5. Selig, L., Pages, J. C., Tanehou, V., Preveral, S., Berlioz-Torrent, C., Liu, L. X., Erdtmann, L., Darlix, J., Benarous, R., and Benichou, S. (1999) J. Virol. 73, 592-600
6. Bachand, F., Yao, X. J., Hrimech, M., Rougeau, N., and Cohen, E. A. (1999) J. Biol. Chem. 274, 9083-9091
7. He, J., Choe, S., Walker, R., Di Marzio, P., Morgan, D. O., and Landau, N. R. (1995) J. Virol. 69, 6705-6711
8. Heinzinger, N. K., Bukinsky, M. I., Haggerty, S. A., Ragland, A. M., Kewalramani, V., Lee, M. A., Gendelman, H. E., Ratner, L., Stevenson, M., and Emerman, M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7311-7315
9. Jowett, J. B., Planelles, V., Poon, B., Shah, N. P., Chen, M. L., and Chen, I. S. (1995) J. Virol. 69, 6304-6313
10. Rogel, M. E., Wu, L. I., and Emerman, M. (1995) J. Virol. 69, 882-888
11. Mansky, L. M., Preveral, S., Selig, L., Benarous, R., and Benichou, S. (2000) J. Virol. 74, 7039-7047
12. Mansky, L. M., Le Rouzic, E., Benichou, S., and Gajary, L. C. (2003) J. Virol. 77, 2071-2080
13. Popov, S., Rexach, M., Ratner, L., Blobel, G., and Bukrinsky, M. (1998) J. Biol. Chem. 273, 13347-13352
14. Bukrinsky, M. I., Sharova, N., Dempsey, M. P., Stanwick, T. L., Bukrinskaya, A. G., Haggerty, S., and Stevenson, M. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 6580-6584
15. Fouchier, R. A., Meyer, B. E., Simon, J. H., Fischer, U., Albright, A. V., Gonzalez-Scarano, F., and Malim, M. H. (1998) J. Virol. 72, 6004-6013
16. Vodicka, M. A., Koepp, D. M., Silver, P. A., and Emerman, M. (1998) Genes Dev. 12, 175-185
17. Cohen, O. J., and Fauci, A. S. (2001) Adv. Intern. Med. 46, 207-246
18. Bouhamdan, M., Benichou, S., Rey, F., Navarro, J. M., Agostini, I., Spire, B., Camonis, J., Slupphaug, G., Vigne, R., Benarous, R., and Sire, J. (1996) J. Virol. 70, 697-704
19. Chen, R., Wang, H., and Mansky, L. M. (2002) J. Gen. Virol. 83, 2339-2345
20. BouHamdan, M., Xue, Y., Baudat, Y., Hu, B., Sire, J., Pomerantz, R. J., and Duan, L. X. (1998) J. Biol. Chem. 273, 8009-8016
21. Yao, X. J., Lemay, J., Rougeau, N., Clement, M., Kurtz, S., Belhumeur, P., and Cohen, E. A. (2002) J. Biol. Chem. 277, 48816-48826
22. Willetts, K. E., Rey, F., Agostinf, I., Navarro, J. M., Baudat, Y., Vigne, R., and Sire, J. (1999) J. Virol. 73, 1682-1688
23. Priet, S., Navarro, J. M., Gros, N., Querat, G., and Sire, J. (2003) J. Biol. Chem. 278, 4566-4571
24. Mansky, L. M. (1996) Virology 222, 391-400
25. Haug, T., Skorpen, F., Lund, H., and Krokan, H. E. (1994) FEBS Lett. 353, 180-184
26. Kumar, N. V., and Varshney, U. (1994) Nucleic Acids Res. 22, 3737-3741
27. Waters, T. R., Gallinari, P., Jiricny, J., and Swann, P. F. (1999) J. Biol. Chem. 274, 67-74
28. Mansky, L. M. (2003) Virology 307, 116-121
29. Mansky, L. M., and Temin, H. M. (1994) J. Virol. 68, 494-499
30. Mansky, L. M., and Temin, H. M. (1995) J. Virol. 69, 5087-5094
31. Mol, C. D., Arvai, A. S., Sanderson, R. J., Slupphaug, G., Kavli, B., Krokan, H. E., Mosbaugh, D. W., and Tainer, J. A. (1995) Cell 82, 701-708
32. Selig, L., Benichou, S., Rogel, M. E., Wu, L. I., Vodicka, M. A., Sire, J., Benarous, R., and Emerman, M. (1997) J. Virol. 71, 4842-4846
33. Sherman, M. P., and Greene, W. C. (2002) Microbes Infect. 4, 67-73
34. Agostini, I., Navarro, J. M., Bouhamdan, M., Willetts, K., Rey, F., Spire, B., Vigne, R., Pomerantz, R., and Sire, J. (1999) FEBS Lett. 450, 235-239
35. Jacotot, E., Ferri, K. F., El Hamel, C., Brenner, C., Druillennec, S., Hoebeke, J., Rustin, P., Metivier, D., Lenoir, C., Geuskens, M., Vieira, H. L., Loeffler, M., Belzacq, A. S., Briand, J. P., Zamzami, N., Edelman, L., Xie, Z. H., Reed, J. C., Roques, B. P., and Kroemer, G. (2001) J. Exp. Med. 193, 509-519
36. Morellet, N., Bouaziz, S., Petitjean, P., and Roques, B. P. (2003) J. Mol. Biol. 327, 215-227
37. Yao, X. J., Kobinger, G., Dandache, S., Rougeau, N., and Cohen, E. (1999) Gene Ther. 6, 1590-1599
38. Wu, X., Liu, H., Xiao, H., Conway, J. A., Hunter, E., and Kappes, J. C. (1997) EMBO J. 16, 5113-5122
39. Wu, X., Liu, H., Xiao, H., Kim, J., Seshaiah, P., Natsoulis, G., Boeke, J. D., Hahn, B. H., and Kappes, J. C. (1995) J. Virol. 69, 3389-3398
40. Klarmann, G. J., Chen, X., North, T. W., and Preston, B. D. (2003) J. Biol. Chem. 278, 7902-7909
41. Miller, R. J., Cairns, J. S., Bridges, S., and Sarver, N. (2000) J. Virol. 74, 7187-7195
42. Turelli, P., Guiguen, F., Mornex, J. F., Vigne, R., and Querat, G. (1997) J. Virol. 71, 4522-4530
43. Lerner, D. L., Wagaman, P. C., Phillips, T. R., Prospero-Garcia, O., Henriksen, S. J., Fox, H. S., Bloom, F. E., and Elder, J. H. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7480-7484
44. Lichtenstein, D. L., Rushlow, K. E., Cook, R. F., Raabe, M. L., Swardson, C. J., Kociba, G. J., Issel, C. J., and Montelaro, R. C. (1995) J. Virol. 69, 2881-2888
45. Sheehy, A. M., Gaddis, N. C., and Malim, M. H. (2003) Nat. Med. 9, 1404-1467
46. Mangeat, B., Turelli, P., Caron, G., Friedli, M., Perrin, L., and Trono, D. (2003) Nature 424, 99-103
47. Zhang, H., Yang, B., Pomerantz, R. J., Zhang, C., Arunachalam, S. C., and Gao, L. (2003) Nature 424, 94-98
48. Lecossier, D., Bouchonnet, F., Clavel, F., and Hance, A. J. (2003) Science 300, 1112
49. Mariani, R., Chen, D., Schrofelbauer, B., Navarro, F., Konig, R., Bollman, B., Munk, C., Nymark-McMahon, H., and Landau, N. R. (2003) Cell 114, 21-31