The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process

Journal of Experimental Medicine

Volumn 195, Issue 9, 2002, Pages 1193-1198

  Nina Papavasiliou, F ^a   Schatz, David G ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AID; B lymphocyte; DNA double strand breaks; Ig gene; Somatic hypermutation

Indexed keywords

CYTIDINE DEAMINASE; DOUBLE STRANDED DNA; IMMUNOGLOBULIN HEAVY CHAIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; DNA CLEAVAGE; DNA DAMAGE; DNA MODIFICATION; ENZYME ACTIVATION; ENZYME STRUCTURE; GENE SWITCHING; GENETIC RECOMBINATION; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SOMATIC MUTATION;

AMINO ACID SEQUENCE; ANIMALS; B-LYMPHOCYTES; CYTIDINE DEAMINASE; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN MU-CHAINS; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POINT MUTATION; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0037029606     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20011858     Document Type: Article

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