Separate domains of AID are required for somatic hypermutation and class-switch recombination

Nature Immunology

Volumn 5, Issue 7, 2004, Pages 707-712

  Shinkura, Reiko ^a   Ito, Satomi ^a   Begum, Nasim A ^a   Nagaoka, Hitoshi ^a   Muramatsu, Masamichi ^a   Kinoshita, Kazuo ^a   Sakakibara, Yishimasa ^a   Hijikata, Hiroko ^a   Honjo, Tasuku ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; MUTANT PROTEIN; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE);

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; GENE MUTATION; GENETIC REGULATION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SOMATIC HYPERMUTATION; ACTIVE TRANSPORT; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CELL STRAIN 3T3; CHEMISTRY; CYTOLOGY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEAR LOCALIZATION SIGNAL; SPLEEN;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; B-LYMPHOCYTES; CELLS, CULTURED; CYTIDINE DEAMINASE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NIH 3T3 CELLS; NUCLEAR LOCALIZATION SIGNALS; RECOMBINATION, GENETIC; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; SPLEEN;

EID: 3242795967     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1086     Document Type: Article

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