DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 6, 2005, Pages 2022-2027

  Nagaoka, Hitoshi ^a   Ito, Satomi ^a   Muramatsu, Masamichi ^a   Nakata, Mikiyo ^a   Honjo, Tasuku ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; CYTIDINE DEAMINASE; CYTOSINE; ENDONUCLEASE; HISTONE; HISTONE H2AX; IMMUNOGLOBULIN; MESSENGER RNA; PROTEIN SYNTHESIS INHIBITOR; UNCLASSIFIED DRUG; URACIL; URACIL DNA GLYCOSYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEAMINATION; DNA CLEAVAGE; ENZYME ACTIVATION; MARKER GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RNA EDITING; SOMATIC HYPERMUTATION;

ANIMALS; CELL LINE; CYCLOHEXIMIDE; CYTIDINE DEAMINASE; CYTOSINE DEAMINASE; DNA; DNA GLYCOSYLASES; FIBROBLASTS; HISTONES; HUMANS; MICE; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; RECOMBINANT FUSION PROTEINS; RNA EDITING; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; URACIL-DNA GLYCOSIDASE;

ANIMALIA;

EID: 13844315325     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0409491102     Document Type: Article

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