RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

Molecular Cell

Volumn 10, Issue 5, 2002, Pages 1247-1253

  Harris, Reuben S ^a   Petersen Mahrt, Svend K ^a   Neuberger, Michael S ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; CYTIDINE DEAMINASE; DNA; ENZYME; PROTEIN APOBEC3C; RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CANCER; CONTROLLED STUDY; DEAMINATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; GENE MUTATION; NONHUMAN; RNA EDITING;

ESCHERICHIA COLI;

EID: 0036863733     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00742-6     Document Type: Article

References (31)

1. Anant S., Mukhopadhyay D., Sankaranand V., Kennedy S., Henderson J.O., Davidson N.O. ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing. Am. J. Physiol. Cell Physiol. 281:2001;C1904-C1916.
2. Arakawa H., Hauschild J., Buerstedde J.M. Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion. Science. 295:2002;1301-1306.
3. Bass B.L. RNA editing by adenosine deaminases that act on RNA. Annu. Rev. Biochem. 71:2002;817-846.
4. Bemark M., Neuberger M.S. The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line. Oncogene. 19:2000;3404-3410.
5. Di Noia J., Neuberger M.S. Altering the pathway of immunoglobin hypermutation by inhibiting uracil-DNA glycosylase. Nature. 419:2002;43-48.
6. Harris R.S., Sale J.E., Petersen-Mahrt S.K., Neuberger M.S. AID is essential for immunoglobulin V gene conversion in a cultured B cell line. Curr. Biol. 12:2002;435-438.
7. Jarmuz A., Chester A., Bayliss J., Gisbourne J., Dunham I., Scott J., Navaratnam N. An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics. 79:2002;285-296.
8. Krogan N.J., Zaharik M.L., Neuhard J., Kelln R.A. A combination of three mutations, dcd, pyrH, and cdd, establishes thymidine (Deoxyuridine) auxotrophy in thyA+ strains of Salmonella typhimurium. J. Bacteriol. 180:1998;5891-5895.
9. Lellek H., Kirsten R., Diehl I., Apostel F., Buck F., Greeve J. Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex. J. Biol. Chem. 275:2000;19848-19856.
10. Lindahl T. Instability and decay of the primary structure of DNA. Nature. 362:1993;709-715.
11. Lindahl T. Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair. Mutat. Res. 462:2000;129-135.
12. Loeb L.A. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51:1991;3075-3079.
13. Madsen P., Anant S., Rasmussen H.H., Gromov P., Vorum H., Dumanski J.P., Tommerup N., Collins J.E., Wright C.L., Dunham I.et al. Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1. J. Invest. Dermatol. 113:1999;162-169.
14. Mehta A., Kinter M.T., Sherman N.E., Driscoll D.M. Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA. Mol. Cell. Biol. 20:2000;1846-1854.
15. Migliazza A., Martinotti S., Chen W., Fusco C., Ye B.H., Knowles D.M., Offit K., Chaganti R.S., Dalla-Favera R. Frequent somatic hypermutation of the 5′ noncoding region of the BCL6 gene in B-cell lymphoma. Proc. Natl. Acad. Sci. USA. 92:1995;12520-12524.
16. Muramatsu M., Sankaranand V.S., Anant S., Sugai M., Kinoshita K., Davidson N.O., Honjo T. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J. Biol. Chem. 274:1999;18470-18476.
17. Muramatsu M., Kinoshita K., Fagarasan S., Yamada S., Shinkai Y., Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 102:2000;553-563.
18. Navaratnam N., Fujino T., Bayliss J., Jarmuz A., How A., Richardson N., Somasekaram A., Bhattacharya S., Carter C., Scott J. Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition. J. Mol. Biol. 275:1998;695-714.
19. Olivier M., Eeles R., Hollstein M., Khan M.A., Harris C.C., Hainaut P. The IARC TP53 database. New online mutation analysis and recommendations to users Hum. Mutat. 19:2002;607-614.
20. Pasqualucci L., Neumeister P., Goossens T., Nanjangud G., Chaganti R.S., Kuppers R., Dalla-Favera R. Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas. Nature. 412:2001;341-346.
21. Petersen-Mahrt S.K., Harris R.S., Neuberger M.S. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature. 418:2002;99-104.
22. Powell L.M., Wallis S.C., Pease R.J., Edwards Y.H., Knott T.J., Scott J. A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine. Cell. 50:1987;831-840.
23. Rabbitts T.H., Hamlyn P.H., Baer R. Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma. Nature. 306:1983;760-765.
24. Revy P., Muto T., Levy Y., Geissmann F., Plebani A., Sanal O., Catalan N., Forveille M., Dufourcq-Labelouse R., Gennery A.et al. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell. 102:2000;565-575.
25. Schaaper R.M. Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli. J. Biol. Chem. 268:1993;23762-23765.
26. Sheehy A.M., Gaddis N.C., Choi J.D., Malim M.H. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature. 418:2002;646-658.
27. Shen H.M., Peters A., Baron B., Zhu X., Storb U. Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes. Science. 280:1998;1750-1752.
28. Teng B., Burant C.F., Davidson N.O. Molecular cloning of an apolipoprotein B messenger RNA editing protein. Science. 260:1993;1816-1819.
29. Watanabe N., Okochi E., Mochizuki M., Sugimura T., Ushijima T. The presence of single nucleotide instability in human breast cancer cell lines. Cancer Res. 61:2001;7739-7742.
30. Yamanaka S., Balestra M.E., Ferrell L.D., Fan J., Arnold K.S., Taylor S., Taylor J.M., Innerarity T.L. Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. Proc. Natl. Acad. Sci. USA. 92:1995;8483-8487.
31. Yamanaka S., Poksay K.S., Arnold K.S., Innerarity T.L. A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme. Genes Dev. 11:1997;321-333.