SMUG1 is able to excise uracil from immunoglobulin genes: Insight into mutation versus repair

EMBO Journal

Volumn 25, Issue 3, 2006, Pages 585-595

  Di Noia, Javier M ^a   Rada, Cristina ^a   Neuberger, Michael S ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Antibody diversification; DNA deamination; SMUG1; UNG; Uracil DNA glycosylase

Indexed keywords

DEOXYRIBONUCLEOPROTEIN; SINGLE STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE PROTEIN; UNCLASSIFIED DRUG; URACIL; URACIL DNA GLYCOSYLTRANSFERASE;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; GENE MUTATION; GENE OVEREXPRESSION; IMMUNOGLOBULIN GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ANIMALS; ANTIBODY DIVERSITY; B-LYMPHOCYTES; CELL LINE; CHICKENS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN ISOTYPES; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; MUTATION; URACIL; URACIL-DNA GLYCOSIDASE;

ANIMALIA; MAMMALIA; MUS MUSCULUS;

EID: 32544439248     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600939     Document Type: Article

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