Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively

Nucleic Acids Research

Volumn 26, Issue 20, 1998, Pages 4611-4617

  Otterlei, Marit ^a   Haug, Terje ^a   Nagelhus, Toril A ^a   Slupphaug, Geir ^a   Lindmo, Tore ^a   Krokan, Hans E ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; URACIL DNA GLYCOSYLTRANSFERASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL NUCLEUS; ENZYME LOCALIZATION; HUMAN; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN TARGETING;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; DNA GLYCOSYLASES; HELA CELLS; HUMANS; ISOENZYMES; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; N-GLYCOSYL HYDROLASES; NUCLEAR LOCALIZATION SIGNALS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; TRANSFECTION; URACIL-DNA GLYCOSIDASE;

EID: 0032531934     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/26.20.4611     Document Type: Article

References (36)

1. Kubota, Y., Nash, R.A., Klungland, A., Schar, P., Barnes, D.E. and Lindahl, T. (1996) EMBO J., 15, 6662-6670.
2. Nicholl, I.D., Nealon, K. and Kenny, M.K. (1997) Biochemistry, 36, 7557-7566.
3. Krokan, H.E., Standal, R. and Slupphaug, G. (1997) Biochem. J., 325, 1-16.
4. Impellizzeri, K.J., Anderson, B. and Burgers, P.M.J. (1991). J. Bacteriol., 173, 6807-6810.
5. Haug, T., Skorpen, F., Kvaløy, K., Eftedal, I., Lund, H. and Krokan, H.E. (1996) Genomics, 36, 408-416.
6. Nilsen, H., Otterlei, M., Haug, T., Solum, K., Nagelhus, T.A., Skorpen, F. and Krokan, H.E. (1997) Nucleic Acids Res., 25, 750-755.
7. Haug, T., Skorpen, F., Aas, P.A., Malm, V., Skjelbred, C. and Krokan, H.E. (1998) Nucleic Acids Res., 26, 1449-1457.
8. Mol, C.D., Arvai, A.S., Slupphaug, G., Kavli, B., Alseth, I., Krokan, H.E. and Tainer, J.A. (1995) Cell, 80, 869-878.
9. Slupphaug, G., Mol, C.D., Kavli, B., Arvai, A.S., Krokan, H.E. and Tainer, J.A. (1996) Nature, 384, 87-92.
10. Nagelhus, T.A, Haug, T., Singh, K.K., Keshav, K.F., Skorpen, F., Otterlei, M., Bharati, S., Lindmo, T., Benichou, S., Benarous, R. and Krokan, H.E. (1997) J. Biol. Chem., 272, 6561-6566.
11. Slupphaug, G., Eftedal, I., Kavlie, B., Bharati, S., Helle, N.M., Haug, T., Levine, D.W. and Krokan, H.E. (1995) Biochemistry, 34, 128-138.
12. Nagelhus, T.A., Slupphaug, G., Lindmo, T. and Krokan, H.E. (1995) Exp. Cell Res., 220, 292-297.
13. Dang, C.V. and Lee, W.M. (1989) J. Biol. Chem., 264, 18019-18023.
14. Nix, D.A., and Beckerle, M.C. (1997) J. Cell Biol. 138, 1139-1147.
15. Ladner, R.D. and Caradonna, S.J. (1997) J. Biol. Chem., 272, 19072-19080.
16. Aburatani, H., Hippo, Y., Ishida, T., Takashima, R., Matsuba, C. Kodama, T. Takao, M., Yasui, A., Yamamoto, K. and Asano, M. (1997) Cancer Res., 57, 2151-2156.
17. Pendlebury, A., Frayling, I.M., Santibanez Koref, M.F., Margison, G.P. and Rafferty, J.A. (1994) Carcinogenesis, 15, 2957-2960.
18. Bjørås, M., Luna, L., Johnsen, B., Hoff, E., Haug, T., Rognes, T. and Seeberg, E. (1997) EMBO J., 16, 6314-6322.
19. Croteau, D.L., ap Rhys, C.M., Hudson, E.K., Dianov, G.L., Hansford, R.G. and Bohr, V.A. (1997) J. Biol. Chem., 272, 27338-27344.
20. Takao, M., Aburatani, H., Kobayashi, K. and Yasui, A. (1998) Nucleic Acids Res., 26, 2917-2922.
21. LeDoux, S.P., Wilson, G.L., Beecham, E.J., Stevnsner, T., Wassermann, K. and Bohr, V.A. (1992) Carcinogenesis, 13, 1967-1973.
22. Bohr, V.A. (1995) Carcinogenesis, 16, 2885-2892.
23. Pinz, K.G. and Bogenhagen, D.F. (1998) Mol. Cell. Biol., 18, 1257-1265.
24. Larsson, N.G., Garman, J.D., Oldfors, A., Barsh, G.S. and Clayton, D.A. (1996) Nature Genet., 13, 296-302.
25. Li, J.M., Hopper, A.K. and Martin, N.C, (1989) J. Cell. Biol., 109, 1411-1419.
26. Dingwall, C. and Laskey, R.A. (1991) Trends Biochem. Sci., 16, 478-481.
27. Hicks, G.R. and Raikhel, N.V. (1995) Annu. Rev. Cell Dev. Biol., 11, 155-188.
28. Görlich, D. and Mattaj, I.W. (1996) Science, 271, 1513-1518.
29. Jans, D.A. and Hübner, S. (1996) Physiol. Rev., 76, 651-685.
30. Makkerh, J.P.S., Dingwall, C. and Laskey, R.A. (1996) Curr. Biol., 6, 1025-1027.
31. von Heijne, G. (1986) EMBO J., 5, 1335-1342.
32. Roise, D., Theiler, F., Horvath, S.J., Tomich, J.M., Richards, J.H., Allison, D.S. and Schatz, G. (1988) EMBO J., 7, 649-653.
33. Schatz, G. (1996) J. Biol. Chem., 271, 31763-31766.
34. Neupert, W. (1997) Annu. Rev. Biochem., 66, 863-917.
35. Landry, S.J. and Gierasch, L.M. (1991) Biochemistry, 30, 7359-7362.
36. Hammen, P.K., Gorenstein, D.G. and Weiner, H. (1996) Biochemistry, 35, 3772-3781.