메뉴 건너뛰기




Volumn 19, Issue 4, 2003, Pages 479-489

Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; HISTONE; TRICHOSTATIN A;

EID: 0142188274     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(03)00261-9     Document Type: Article
Times cited : (85)

References (54)
  • 1
    • 0033681250 scopus 로고    scopus 로고
    • Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter
    • Agalioti T., Lomvardas S., Parekh B., Yie J., Maniatis T., Thanos D. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter. Cell. 103:2000;667-678.
    • (2000) Cell , vol.103 , pp. 667-678
    • Agalioti, T.1    Lomvardas, S.2    Parekh, B.3    Yie, J.4    Maniatis, T.5    Thanos, D.6
  • 2
    • 0036850346 scopus 로고    scopus 로고
    • Deciphering the transcriptional histone acetylation code for a human gene
    • Agalioti T., Chen G., Thanos D. Deciphering the transcriptional histone acetylation code for a human gene. Cell. 111:2002;381-392.
    • (2002) Cell , vol.111 , pp. 381-392
    • Agalioti, T.1    Chen, G.2    Thanos, D.3
  • 3
    • 0035871625 scopus 로고    scopus 로고
    • Increased transcription levels induce higher mutation rates in a hypermutating cell line
    • Bachl J., Carlson C., Gray-Schopfer V., Dessing M., Olsson C. Increased transcription levels induce higher mutation rates in a hypermutating cell line. J. Immunol. 166:2001;5051-5057.
    • (2001) J. Immunol. , vol.166 , pp. 5051-5057
    • Bachl, J.1    Carlson, C.2    Gray-Schopfer, V.3    Dessing, M.4    Olsson, C.5
  • 4
    • 0036532026 scopus 로고    scopus 로고
    • Histone modifications in transcriptional regulation
    • Berger S.L. Histone modifications in transcriptional regulation. Curr. Opin. Genet. Dev. 12:2002;142-148.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 142-148
    • Berger, S.L.1
  • 5
    • 0028270307 scopus 로고
    • Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region
    • Betz A.G., Milstein C., Gonzalez-Fernandez A., Pannell R., Larson T., Neuberger M.S. Elements regulating somatic hypermutation of an immunoglobulin κ gene. critical role for the intron enhancer/matrix attachment region Cell. 77:1994;239-248.
    • (1994) Cell , vol.77 , pp. 239-248
    • Betz, A.G.1    Milstein, C.2    Gonzalez-Fernandez, A.3    Pannell, R.4    Larson, T.5    Neuberger, M.S.6
  • 6
    • 0037388165 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
    • Bransteitter R., Pham P., Scharff M.D., Goodman M.F. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc. Natl. Acad. Sci. USA. 100:2003;4102-4107.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4102-4107
    • Bransteitter, R.1    Pham, P.2    Scharff, M.D.3    Goodman, M.F.4
  • 7
    • 0033637358 scopus 로고    scopus 로고
    • DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation
    • Bross L., Fukita Y., McBlane F., Demolliere C., Rajewsky K., Jacobs H. DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation. Immunity. 13:2000;589-597.
    • (2000) Immunity , vol.13 , pp. 589-597
    • Bross, L.1    Fukita, Y.2    McBlane, F.3    Demolliere, C.4    Rajewsky, K.5    Jacobs, H.6
  • 8
    • 0036532118 scopus 로고    scopus 로고
    • ChIPs of the beta-globin locus: Unraveling gene regulation within an active domain
    • Bulger M., Sawado T., Schubeler D., Groudine M. ChIPs of the beta-globin locus. unraveling gene regulation within an active domain Curr. Opin. Genet. Dev. 12:2002;170-177.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 170-177
    • Bulger, M.1    Sawado, T.2    Schubeler, D.3    Groudine, M.4
  • 10
    • 0037452080 scopus 로고    scopus 로고
    • Transcription-targeted DNA deamination by the AID antibody diversification enzyme
    • Chaudhuri J., Tian M., Khuong C., Chua K., Pinaud E., Alt F.W. Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature. 422:2003;726-730.
    • (2003) Nature , vol.422 , pp. 726-730
    • Chaudhuri, J.1    Tian, M.2    Khuong, C.3    Chua, K.4    Pinaud, E.5    Alt, F.W.6
  • 11
    • 0035890244 scopus 로고    scopus 로고
    • Stepwise activation of the immunoglobulin mu heavy chain gene locus
    • Chowdhury D., Sen R. Stepwise activation of the immunoglobulin mu heavy chain gene locus. EMBO J. 20:2001;6394-6403.
    • (2001) EMBO J. , vol.20 , pp. 6394-6403
    • Chowdhury, D.1    Sen, R.2
  • 13
    • 0037206851 scopus 로고    scopus 로고
    • Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota
    • a
    • Faili A., Aoufouchi S., Flatter E., Gueranger Q., Reynaud C.A., Weill J.C. Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota. Nature. 419:2002;944-947. a.
    • (2002) Nature , vol.419 , pp. 944-947
    • Faili, A.1    Aoufouchi, S.2    Flatter, E.3    Gueranger, Q.4    Reynaud, C.A.5    Weill, J.C.6
  • 15
    • 0032127810 scopus 로고    scopus 로고
    • Somatic hypermutation in the heavy chain locus correlates with transcription
    • Fukita Y., Jacobs H., Rajewsky K. Somatic hypermutation in the heavy chain locus correlates with transcription. Immunity. 9:1998;105-114.
    • (1998) Immunity , vol.9 , pp. 105-114
    • Fukita, Y.1    Jacobs, H.2    Rajewsky, K.3
  • 16
    • 0033517821 scopus 로고    scopus 로고
    • Activation of p53 in MDM2-overexpressing cells through phosphorylation
    • Gao C., Nakajima T., Taya Y., Tsuchida N. Activation of p53 in MDM2-overexpressing cells through phosphorylation. Biochem. Biophys. Res. Commun. 264:1999;860-864.
    • (1999) Biochem. Biophys. Res. Commun. , vol.264 , pp. 860-864
    • Gao, C.1    Nakajima, T.2    Taya, Y.3    Tsuchida, N.4
  • 17
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., Allis C.D. Translating the histone code. Science. 293:2001;1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 18
    • 0037378479 scopus 로고    scopus 로고
    • Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development
    • Johnson K., Angelin-Duclos C., Park S., Calame K.L. Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development. Mol. Cell. Biol. 23:2003;2438-2450.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2438-2450
    • Johnson, K.1    Angelin-Duclos, C.2    Park, S.3    Calame, K.L.4
  • 19
    • 0033526760 scopus 로고    scopus 로고
    • Different mismatch repair deficiencies all have the same effects on somatic hypermutation: Intact primary mechanism accompanied by secondary modifications
    • Kim N., Bozek G., Lo J.C., Storb U. Different mismatch repair deficiencies all have the same effects on somatic hypermutation. intact primary mechanism accompanied by secondary modifications J. Exp. Med. 190:1999;21-30.
    • (1999) J. Exp. Med. , vol.190 , pp. 21-30
    • Kim, N.1    Bozek, G.2    Lo, J.C.3    Storb, U.4
  • 20
    • 0031758348 scopus 로고    scopus 로고
    • Promotion of antigen-specific antibody production in murine B cells by a moderate increase in histone acetylation
    • Kohge T., Gohda E., Okamura T., Yamamoto I. Promotion of antigen-specific antibody production in murine B cells by a moderate increase in histone acetylation. Biochem. Pharmacol. 56:1998;1359-1364.
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 1359-1364
    • Kohge, T.1    Gohda, E.2    Okamura, T.3    Yamamoto, I.4
  • 21
    • 0035003254 scopus 로고    scopus 로고
    • DNA breaks in hypermutating immunoglobulin genes: Evidence for a break and repair pathway of somatic mutation
    • Kong Q., Maizels N. DNA breaks in hypermutating immunoglobulin genes. evidence for a break and repair pathway of somatic mutation Genetics. 158:2001;369-378.
    • (2001) Genetics , vol.158 , pp. 369-378
    • Kong, Q.1    Maizels, N.2
  • 22
    • 0033638506 scopus 로고    scopus 로고
    • Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA
    • Kwon J., Morshead K.B., Guyon J.R., Kingston R.E., Oettinger M.A. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol. Cell. 6:2000;1037-1048.
    • (2000) Mol. Cell , vol.6 , pp. 1037-1048
    • Kwon, J.1    Morshead, K.B.2    Guyon, J.R.3    Kingston, R.E.4    Oettinger, M.A.5
  • 23
    • 0025630537 scopus 로고
    • Boundaries of somatic mutation in rearranged immunoglobulin genes: 5′ boundary is near the promoter, and 3′ boundary is approximately 1 kb from V(D)J gene
    • Lebecque S.G., Gearhart P.J. Boundaries of somatic mutation in rearranged immunoglobulin genes. 5′ boundary is near the promoter, and 3′ boundary is approximately 1 kb from V(D)J gene J. Exp. Med. 172:1990;1717-1727.
    • (1990) J. Exp. Med. , vol.172 , pp. 1717-1727
    • Lebecque, S.G.1    Gearhart, P.J.2
  • 24
    • 0342445442 scopus 로고    scopus 로고
    • Dynamic analysis of proviral induction and de novo methylation: Implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression
    • Lorincz M.C., Schubeler D., Goeke S.C., Walters M., Groudine M., Martin D.I. Dynamic analysis of proviral induction and de novo methylation. implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression Mol. Cell. Biol. 20:2000;842-850.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 842-850
    • Lorincz, M.C.1    Schubeler, D.2    Goeke, S.C.3    Walters, M.4    Groudine, M.5    Martin, D.I.6
  • 26
    • 0028818503 scopus 로고
    • Somatic hypermutation: How many mechanisms diversify V region sequences?
    • Maizels N. Somatic hypermutation. how many mechanisms diversify V region sequences? Cell. 83:1995;9-12.
    • (1995) Cell , vol.83 , pp. 9-12
    • Maizels, N.1
  • 27
    • 0037126038 scopus 로고    scopus 로고
    • Somatic hypermutation of the AID transgene in B and non-B cells
    • Martin A., Scharff M.D. Somatic hypermutation of the AID transgene in B and non-B cells. Proc. Natl. Acad. Sci. USA. 99:2002;12304-12308.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12304-12308
    • Martin, A.1    Scharff, M.D.2
  • 28
    • 0037074975 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas
    • Martin A., Bardwell P.D., Woo C.J., Fan M., Shulman M.J., Scharff M.D. Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas. Nature. 415:2002;802-806.
    • (2002) Nature , vol.415 , pp. 802-806
    • Martin, A.1    Bardwell, P.D.2    Woo, C.J.3    Fan, M.4    Shulman, M.J.5    Scharff, M.D.6
  • 29
    • 0034695501 scopus 로고    scopus 로고
    • A role for histone acetylation in the developmental regulation of V(D)J recombination
    • McMurry M.T., Krangel M.S. A role for histone acetylation in the developmental regulation of V(D)J recombination. Science. 287:2000;495-498.
    • (2000) Science , vol.287 , pp. 495-498
    • McMurry, M.T.1    Krangel, M.S.2
  • 31
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M., Kinoshita K., Fagarasan S., Yamada S., Shinkai Y., Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 102:2000;553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 32
    • 0034626802 scopus 로고    scopus 로고
    • Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes
    • Papavasiliou F.N., Schatz D.G. Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes. Nature. 408:2000;216-221.
    • (2000) Nature , vol.408 , pp. 216-221
    • Papavasiliou, F.N.1    Schatz, D.G.2
  • 33
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • Paull T.T., Rogakou E.P., Yamazaki V., Kirchgessner C.U., Gellert M., Bonner W.M. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10:2000;886-895.
    • (2000) Curr. Biol. , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 34
    • 0030063726 scopus 로고    scopus 로고
    • Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
    • Peters A., Storb U. Somatic hypermutation of immunoglobulin genes is linked to transcription initiation. Immunity. 4:1996;57-65.
    • (1996) Immunity , vol.4 , pp. 57-65
    • Peters, A.1    Storb, U.2
  • 37
    • 2642652230 scopus 로고    scopus 로고
    • The 5′ hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription
    • Rada C., Yelamos J., Dean W., Milstein C. The 5′ hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription. Eur. J. Immunol. 27:1997;3115-3120.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3115-3120
    • Rada, C.1    Yelamos, J.2    Dean, W.3    Milstein, C.4
  • 38
    • 0038293484 scopus 로고    scopus 로고
    • Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
    • Ramiro A.R., Stavropoulos P., Jankovic M., Nussenzweig M.C. Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand. Nat. Immunol. 4:2003;452-456.
    • (2003) Nat. Immunol. , vol.4 , pp. 452-456
    • Ramiro, A.R.1    Stavropoulos, P.2    Jankovic, M.3    Nussenzweig, M.C.4
  • 40
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273:1998;5858-5868.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 41
    • 0026443954 scopus 로고
    • Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis
    • Rogozin I.B., Kolchanov N.A. Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis. Biochim. Biophys. Acta. 1171:1992;11-18.
    • (1992) Biochim. Biophys. Acta , vol.1171 , pp. 11-18
    • Rogozin, I.B.1    Kolchanov, N.A.2
  • 42
    • 0032435650 scopus 로고    scopus 로고
    • TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line
    • Sale J.E., Neuberger M.S. TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line. Immunity. 9:1998;859-869.
    • (1998) Immunity , vol.9 , pp. 859-869
    • Sale, J.E.1    Neuberger, M.S.2
  • 45
    • 0013801328 scopus 로고
    • Effect of variation in antibody-hapten association constant upon the biologic activity of the antibody
    • Siskind G.W., Eisen H.N. Effect of variation in antibody-hapten association constant upon the biologic activity of the antibody. J. Immunol. 95:1965;436-441.
    • (1965) J. Immunol. , vol.95 , pp. 436-441
    • Siskind, G.W.1    Eisen, H.N.2
  • 46
    • 0029983727 scopus 로고    scopus 로고
    • Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements
    • Sleckman B.P., Gorman J.R., Alt F.W. Accessibility control of antigen-receptor variable-region gene assembly. role of cis-acting elements Annu. Rev. Immunol. 14:1996;459-481.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 459-481
    • Sleckman, B.P.1    Gorman, J.R.2    Alt, F.W.3
  • 49
    • 0034175616 scopus 로고    scopus 로고
    • Analysis of promoter binding by the E2F and pRB families in vivo: Distinct E2F proteins mediate activation and repression
    • Takahashi Y., Rayman J.B., Dynlacht B.D. Analysis of promoter binding by the E2F and pRB families in vivo. distinct E2F proteins mediate activation and repression Genes Dev. 14:2000;804-816.
    • (2000) Genes Dev. , vol.14 , pp. 804-816
    • Takahashi, Y.1    Rayman, J.B.2    Dynlacht, B.D.3
  • 50
    • 0031041632 scopus 로고    scopus 로고
    • The transcriptional promoter regulates hypermutation of the antibody heavy chain locus
    • Tumas-Brundage K., Manser T. The transcriptional promoter regulates hypermutation of the antibody heavy chain locus. J. Exp. Med. 185:1997;239-250.
    • (1997) J. Exp. Med. , vol.185 , pp. 239-250
    • Tumas-Brundage, K.1    Manser, T.2
  • 51
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative PCR data by geometric averaging of multiple internal control genes
    • Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. Accurate normalization of real-time quantitative PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3:2002;1-12.
    • (2002) Genome Biol. , vol.3 , pp. 1-12
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 52
    • 0014943022 scopus 로고
    • Variability in the lambda light chain sequences of mouse antibody
    • Weigert M.G., Cesari I.M., Yonkovich S.J., Cohn M. Variability in the lambda light chain sequences of mouse antibody. Nature. 228:1970;1045-1047.
    • (1970) Nature , vol.228 , pp. 1045-1047
    • Weigert, M.G.1    Cesari, I.M.2    Yonkovich, S.J.3    Cohn, M.4
  • 54
    • 0033559138 scopus 로고    scopus 로고
    • Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: Definition of the requirements and modalities of hypermutation
    • Zan H., Cerutti A., Dramitinos P., Schaffer A., Li Z., Casali P. Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro. definition of the requirements and modalities of hypermutation J. Immunol. 162:1999;3437-3447.
    • (1999) J. Immunol. , vol.162 , pp. 3437-3447
    • Zan, H.1    Cerutti, A.2    Dramitinos, P.3    Schaffer, A.4    Li, Z.5    Casali, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.