Cytochrome P-450 3A4: Regulation and role in drug metabolism

Annual Review of Pharmacology and Toxicology

Volumn 39, Issue , 1999, Pages 1-17

  Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cooperativity; Genetic polymorphism; Heterologous expression; Nifedipine oxidation; P 170 glycoprotein

Indexed keywords

ALFENTANIL; ALPIDEM; ALPRAZOLAM; AMIODARONE; AMITRIPTYLINE; ARTELINIC ACID; ASTEMIZOLE; ATORVASTATIN; BUDESONIDE; CLOPIDOGREL; CLOZAPINE; CODEINE; CYTOCHROME P450; DAPSONE; DIGITOXIN; DILTIAZEM; ETOPOSIDE; FLUTAMIDE; GESTODENE; HYDROCORTISONE; INDINAVIR; IRINOTECAN; LIDOCAINE; MEVINOLIN; PARACETAMOL; RITONAVIR; SUFENTANIL; TENIPOSIDE; TERGURIDE; UNINDEXED DRUG;

CATALYSIS; DNA FLANKING REGION; DRUG BIOAVAILABILITY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; GENE INDUCTION; HORMONE RESPONSIVE ELEMENT; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MIXED FUNCTION OXYGENASES; PHARMACEUTICAL PREPARATIONS;

EID: 0032924934     PISSN: 03621642     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.39.1.1     Document Type: Review

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