Dual targeting of cytochrome P4502B1 to endoplasmic reticulum and mitochondria involves a novel signal activation by cyclic AMP-dependent phosphorylation at Ser128

EMBO Journal

Volumn 18, Issue 20, 1999, Pages 5494-5504

  Anandatheerthavarada, Hindupur K ^a   Biswas, Gopa ^a   Mullick, Jayati ^a   Sepuri, Naresh Babu V ^b   Otvos, Laszlo ^c   Pain, Debkumar ^b   Avadhani, Narayan G ^a  

^a UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WISTAR INSTITUTE   (United States)

Author keywords

cAMP; Chimeric signal; Mitochondrial targeting; P4502B1; Protein phosphorylation

Indexed keywords

CARRIER PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHROME P450 ISOENZYME; DIHYDROFOLATE REDUCTASE; HYBRID PROTEIN; SERINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CROSS REACTION; ENDOPLASMIC RETICULUM; LIVER MITOCHONDRION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; RAT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; COS CELLS; CYCLIC AMP; CYTOCHROME P-450 CYP2B1; ENDOPLASMIC RETICULUM; MITOCHONDRIA; MITOCHONDRIA, LIVER; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHENOBARBITAL; PHOSPHORYLATION; PROTEIN SORTING SIGNALS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS;

EID: 0033570145     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.20.5494     Document Type: Article

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