AMPA receptor ligands: Synthetic and pharmacological studies of polyamines and polyamine toxins

Medicinal Research Reviews

Volumn 24, Issue 5, 2004, Pages 589-620

  Strømgaard, Kristian ^a   Mellor, Ian ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

AMPA receptors; Channel block; Inward rectification; Medicinal chemistry; Pharmacology; Polyamine; Polyamine toxins; Solid phase synthesis

Indexed keywords

1 (1 ADAMANTYLMETHYLAMMONIO) 5 TRIMETHYLAMMONIOPENTANE DIBROMIDE; 1 (4 AMINOPHENYL) 3,4 DIHYDRO 4 METHYL 3 METHYLCARBAMOYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 4 AMINOBUTYRIC ACID A RECEPTOR; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; 6,7 DINITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; AMPA RECEPTOR AGONIST; AMPA RECEPTOR ANTAGONIST; CALCIUM ION; DECAHYDRO 6 [2 (1H TETRAZOL 5 YL)ETHYL] 3 ISOQUINOLINECARBOXYLIC ACID; GLUTAMIC ACID; GLYCINE RECEPTOR; IONOTROPIC RECEPTOR; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINIC RECEPTOR; PHILANTHOTOXIN; PHILANTHOTOXIN 343; POLYAMINE DERIVATIVE; POTASSIUM CHANNEL; QUISQUALIC ACID; SEROTONIN 3 RECEPTOR; SODIUM ION; SPERMIDINE; SPERMINE; SQUARIC ACID; TOXIN; UNINDEXED DRUG;

CHANNEL GATING; DRUG MECHANISM; DRUG RECEPTOR BINDING; HUMAN; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; REVIEW; SYNTHESIS;

ANIMALS; DRUG INDUSTRY; HUMANS; ION CHANNELS; LIGANDS; POLYAMINES; RECEPTORS, AMPA; RECEPTORS, GLUTAMATE; STRUCTURE-ACTIVITY RELATIONSHIP; TOXINS, BIOLOGICAL;

EID: 1942495754     PISSN: 01986325     EISSN: None     Source Type: Journal    
DOI: 10.1002/med.20004     Document Type: Review

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