Solid-phase synthesis of polyamine toxin analogues: Potent and selective antagonists of Ca2+-permeable AMPA receptors

Journal of Medicinal Chemistry

Volumn 45, Issue 26, 2002, Pages 5745-5754

  Kromann, Hasse ^a   Krikstolaityte, Sonata ^a   Andersen, Anne J ^b   Andersen, Kim ^c   Krogsgaard Larsen, Povl ^a   Jaroszewski, Jerzy W ^a   Egebjerg, Jan ^b,c   Strømgaard, Kristian ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c H LUNDBECK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; ION CHANNEL; IONOTROPIC RECEPTOR; KAINIC ACID RECEPTOR; NICOTINIC RECEPTOR; PHILANTHOTOXIN; PHILANTHOTOXIN 83; POLYAMINE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HYDROPHOBICITY; LIPOPHILICITY; NONHUMAN; OVARY; PEPTIDE SYNTHESIS; PROTEIN CONFORMATION; RNA SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; CALCIUM; EXCITATORY AMINO ACID ANTAGONISTS; OOCYTES; PATCH-CLAMP TECHNIQUES; POLYAMINES; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; WASP VENOMS; XENOPUS LAEVIS;

EID: 0037137655     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020314s     Document Type: Article

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