Ca2+-Zn2+ permeable AMPA or kainate receptors: Possible key factors in selective neurodegeneration

Trends in Neurosciences

Volumn 23, Issue 8, 2000, Pages 365-371

  Weiss, John H ^a,b   Sensi, Stefano L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CALCIUM; KAINIC ACID RECEPTOR; ZINC; AMPA RECEPTOR;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; BRAIN ISCHEMIA; ENVIRONMENTAL FACTOR; MEDIATOR RELEASE; MOTONEURON; NERVE DEGENERATION; NEUROLOGIC DISEASE; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; REVIEW; TISSUE DISTRIBUTION; ANIMAL; BRAIN LEVEL; DEGENERATIVE DISEASE; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; BRAIN CHEMISTRY; CALCIUM; HUMANS; NERVE DEGENERATION; NEURODEGENERATIVE DISEASES; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; ZINC;

EID: 0034238089     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(00)01610-6     Document Type: Review

References (85)

1. Olney J.W. Brain lesion, obesity and other disturbances in mice treated with monosodium glutamate. Science. 164:1969;719-721.
2. Choi D.W.et al. Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:1987;357-368.
3. Spencer P.S.et al. Lathyrism: evidence for role of the neuroexcitatory amino acid BOAA. Lancet. 2:1986;1066-1067.
4. Spencer P.S.et al. Guam amyotrophic lateral sclerosis-Parkinsonism-dementia linked to a plant excitant neurotoxin. Science. 237:1987;517-522.
5. Teitelbaum J.S.et al. Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels. New Engl. J. Med. 322:1990;1781-1787.
6. Koh J.Y.et al. Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res. 533:1990;315-320.
7. Mattson M.P.et al. beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12:1992;376-389.
8. Rothstein J.D.et al. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. New Engl. J. Med. 326:1992;1464-1468.
9. Gill R., Lodge D. Pharmacology of AMPA antagonists and their role in neuroprotection. Int. Rev. Neurobiol. 40:1997;197-232.
10. Debonnel G.et al. Domoic acid, the alleged 'mussel toxin,' might produce its neurotoxic effect through kainate receptor activation: an electrophysiological study in the dorsal hippocampus. Can. J. Physiol. Pharmacol. 67:1989;29-33.
11. Weiss J.H.et al. Neurotoxicity of beta-N-methylamino-L-alanine (BMAA) and beta-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons. Brain Res. 497:1989;64-71.
12. Bridges R.J.et al. Structure-function studies on N-oxalyl-diamino-dicarboxylic acids and excitatory amino acid receptors: evidence that beta-L-ODAP is a selective non-NMDA agonist. J. Neurosci. 9:1989;2073-2079.
13. Hugon J.et al. Kainic acid induces early and delayed degenerative neuronal changes in rat spinal cord. Neurosci. Lett. 104:1989;258-262.
14. Rothstein J.D.et al. Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. 90:1993;6591-6595.
15. Carriedo S.G.et al. Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro. J. Neurosci. 16:1996;4069-4079.
16. Page K.J.et al. Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: differential dependence on cholinergic neuronal loss. Neuroscience. 43:1991;457-472.
17. Weiss J.H.et al. Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity. Neuroscience. 60:1994;659-664.
18. Iino M.et al. Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones. J. Physiol. 424:1990;151-165.
19. 2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition. Science. 252:1991;851-853.
20. Verdoorn T.A.et al. Structural determinants of ion flow through recombinant glutamate receptor channels. Science. 252:1991;1715-1718.
21. +1-permeability in both TM1 and TM2 of high affinity kainate receptor channels: diversity by RNA editing. Neuron. 10:1993;491-500.
22. Sommer B.et al. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell. 67:1991;11-19.
23. Bochet P.et al. Subunit composition at the single-cell level explains functional properties of a glutamate-gated channel. Neuron. 12:1994;383-388.
24. 2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression. Neuron. 12:1994;1281-1289.
25. 2+ permeable AMPA/kainate channels display distinct receptor immunoreactivity are GABAergic. Neurobiol. Dis. 1:1994;43-49.
26. Pruss R.M.et al. Agonist-activated cobalt uptake identifies divalent cation-permeable kainate receptors on neurons and glial cells. Neuron. 7:1991;509-518.
27. Brorson J.R.et al. Calcium directly permeates kainate/alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured cerebellar Purkinje neurons. Mol. Pharmacol. 41:1992;603-608.
28. 2+ uptake are selectively vulnerable to AMPA/ kainate receptor-mediated toxicity. Neurobiol. Dis. 1:1994;101-110.
29. 2+-permeable AMPA/kainate receptors. Brain Res. 809:1998;319-324.
30. Bar-Peled O.et al. Cultured motor neurons possess calcium-permeable AMPA/kainate receptors. NeuroReport. 10:1999;855-859.
31. 2+dependent. NeuroReport. 5:1994;1477-1480.
32. Williams T.L.et al. Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors: a molecular determinant of selective vulnerability in amyotrophic lateral sclerosis. Ann. Neurol. 42:1997;200-207.
33. Page K.J., Everitt B.J. The distribution of neurons coexpressing immunoreactivity to AMPA-sensitive glutamate receptor subtypes (GluR1-4) and nerve growth factor receptor in the rat basal forebrain. Eur. J. Neurosci. 7:1995;1022-1033.
34. 2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS. Neuron. 15:1995;193-204.
35. Spruston N.et al. Activity-dependent action potential invasion and calcium influx into hippocampal CA1 dendrites. Science. 268:1995;297-300.
36. 2+ currents through somatic and dendritic glutamate receptor channels of rat hippocampal CA1 pyramidal neurones. J. Physiol. 491:1996;757-772.
37. 2+ permeability of glutamate receptor channels in hippocampal cells. Eur. J. Neurosci. 6:1994;1080-1088.
38. Schneggenburger R.et al. Fractional contribution of calcium to the cation current through glutamate receptor channels. Neuron. 11:1993;133-143.
39. 2+-permeable non-NMDA glutamate receptors in rat magnocellular basal forebrain neurones. J. Physiol. 508:1998;453-469.
40. Vandenberghe W.et al. AMPA receptor calcium permeability, GluR2 expression, and selective motoneuron vulnerability. J. Neurosci. 20:2000;123-132.
41. Greig A.et al. Characterization of the AMPA-activated receptors present on motoneurons. J. Neurochem. 74:2000;179-191.
42. 2+-permeable AMPA/kainate channels in hippocampal pyramidal neurons. J. Comp. Neurol. 409:1999;250-260.
43. Nicholls D.G., Budd S.L. Mitochondria and neuronal survival. Physiol. Rev. 80:2000;315-360.
44. Dugan L.L.et al. Carboxyfullerenes as neuroprotective agents. Proc. Natl. Acad. Sci. U. S. A. 94:1997;9434-9439.
45. 2+ overload induced by endogenous excitatory amino acids following a glutamate pulse. FEBS Lett. 393:1996;135-138.
46. Budd S.L., Nicholls D.G. Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurochem. 67:1996;2282-2291.
47. Stout A.K.et al. Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat. Neurosci. 1:1998;366-373.
48. Burnashev N.et al. Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes. J. Physiol. 485:1995;403-418.
49. 2+ influx underlies potent induction of injury. J. Neurosci. 16:1996;5457-5465.
50. 2+ rises and consequent oxygen radical production. J. Neurosci. 18:1998;7727-7738.
51. 2+ overload and ROS generation in spinal motor neurons in vitro. J. Neurosci. 20:2000;240-250.
52. Pellegrini-Giampietro D.E.et al. Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats. Proc. Natl. Acad. Sci. U. S. A. 89:1992;10 499-10 503.
53. Pollard H.et al. Alterations of the GluR-B AMPA receptor subunit flip/flop expression in kainate-induced epilepsy and ischemia. Neuroscience. 57:1993;545-554.
54. A receptor gene expression in adult rat hippocampus: an in situ hybridization study. J. Neurosci. 14:1994;2697-2707.
55. Grooms S.Y.et al. Status epilepticus decreases glutamate receptor 2 mRNA and protein expression in hippocampal pyramidal cells before neuronal death. Proc. Natl. Acad. Sci. U. S. A. 97:2000;3631-3636.
56. 2+-permeable AMPA receptors in neurological disorders. Trends Neurosci. 20:1997;464-470.
57. Tsubokawa H.et al. Effects of a spider toxin and its analogue on glutamate-activated currents in the hippocampal CA1 neuron after ischemia. J. Neurophysiol. 74:1995;218-225.
58. 2+ influx in hippocampal CA1 neurons of gerbil. J. Neurosci. 17:1997;6179-6188.
59. Dingledine R.et al. The glutamate receptor ion channels. Pharmacol. Rev. 51:1999;7-61.
60. Pagliusi S.R.et al. Age-related changes in expression of AMPA-selective glutamate receptor subunits: is calcium-permeability altered in hippocampal neurons? Neuroscience. 61:1994;429-433.
61. Ikonomovic M.D.et al. The loss of GluR2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of Alzheimer brains. J. Neuropathol. Exp. Neurol. 56:1997;1018-1027.
62. Sommer B.et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 249:1990;1580-1585.
63. Baimbridge K.G.et al. Calcium-binding proteins in the nervous system. Trends Neurosci. 15:1992;303-308.
64. Iihara K.et al. Independence of AMPA receptor-mediated excitotoxicity on calcium influx through GluR2-deficient AMPA receptor. Soc. Neurosci. Abstr. 25:1999;841.
65. Jia Z.et al. Enhanced LTP in mice deficient in the AMPA receptor GluR2. Neuron. 17:1996;945-956.
66. Feldmeyer D.et al. Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B. Nat. Neurosci. 2:1999;57-64.
67. Frederickson C.J. Neurobiology of zinc and zinc-containing neurons. Int. Rev. Neurobiol. 31:1989;145-238.
68. Sloviter R.S. A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation. Brain Res. 330:1985;150-153.
69. Frederickson C.J.et al. Translocation of zinc may contribute to seizure-induced death of neurons. Brain Res. 480:1989;317-321.
70. Koh J.Y.et al. The role of zinc in selective neuronal death after transient global cerebral ischemia. Science. 272:1996;1013-1016.
71. Weiss J.H.et al. AMPA receptor activation potentiates zinc neurotoxicity. Neuron. 10:1993;43-49.
72. Koh J.Y., Choi D.W. Zinc toxicity on cultured cortical neurons: involvement of N-methyl-D-aspartate receptors. Neuroscience. 60:1994;1049-1057.
73. 2+ permeable AMPA/kainate channels and triggers selective neural injury. NeuroReport. 6:1995;2553-2556.
74. 2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production. Proc. Natl. Acad. Sci. U. S. A. 96:1999;2414-2419.
75. 2+ permeable AMPA channels and consequent ROS production. NeuroReport. 10:1999;1723-1727.
76. Manev H.et al. Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells. Exp. Neurol. 146:1997;171-178.
77. Link T.A., von Jagow G. Zinc ions inhibit the QP center of bovine heart mitochondrial bc1 complex by blocking a protonatable group. J. Biol. Chem. 270:1995;25 001-25 006.
78. Wudarczyk J.et al. Zinc as an inducer of the membrane permeability transition in rat liver mitochondria. Arch. Biochem. Biophys. 363:1999;1-8.
79. 2+ entry produces oxidative neuronal necrosis in cortical cell cultures. Eur. J. Neurosci. 11:1999;327-334.
80. Noh K.M.et al. Mediation by membrane protein kinase C of zinc-induced oxidative neuronal injury in mouse cortical cultures. J. Neurochem. 72:1999;1609-1616.
81. Bush A.I.et al. Rapid induction of Alzheimer A beta amyloid formation by zinc. Science. 265:1994;1464-1467.
82. Miller R.J. The revenge of the kainate receptor. Trends Neurosci. 14:1991;477-479.
83. Siesjo B.K.et al. Free radicals and brain damage. Cerebrovasc. Brain Metab. Rev. 1:1989;165-211.
84. Beal M.F. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann. Neurol. 38:1995;357-366.
85. Nicotera P., Lipton S.A. Excitotoxins in neuronal apoptosis and necrosis. J. Cereb. Blood Flow Metab. 19:1999;583-591.